| Assay ID | Title | Year | Journal | Article |
|---|
| AID113017 | In vivo anticonvulsant activity in male albino mice using the maximal electroshock seizure(MES) test upon intraperitoneal administration; value ranges from 9.1 to 11.6 | 2002 | Journal of medicinal chemistry, Jun-20, Volume: 45, Issue:13
| Quantitative structure-activity relationship analysis of functionalized amino acid anticonvulsant agents using k nearest neighbor and simulated annealing PLS methods. |
| AID132226 | Effective dose required for maximal electroshock (MES)-induced seizures in mice. | 1993 | Journal of medicinal chemistry, Oct-29, Volume: 36, Issue:22
| Synthesis and anticonvulsant activities of alpha-heterocyclic alpha-acetamido-N-benzylacetamide derivatives. |
| AID124082 | In vivo anticonvulsant activity in male albino mice using the maximal electroshock seizure(MES) test upon intraperitoneal administration, expressed as logarithm of effective dose | 2002 | Journal of medicinal chemistry, Jun-20, Volume: 45, Issue:13
| Quantitative structure-activity relationship analysis of functionalized amino acid anticonvulsant agents using k nearest neighbor and simulated annealing PLS methods. |
| AID480288 | Protective index, ratio of TD50 for albino mouse to anticonvulsant ED50 for albino mouse | 2010 | Journal of medicinal chemistry, May-13, Volume: 53, Issue:9
| Merging the structural motifs of functionalized amino acids and alpha-aminoamides: compounds with significant anticonvulsant activities. |
| AID131201 | Concentration required to inhibit seizures was determined in MES test after (ip) administration in mice | 1990 | Journal of medicinal chemistry, Mar, Volume: 33, Issue:3
| Preparation and anticonvulsant activity of a series of functionalized alpha-aromatic and alpha-heteroaromatic amino acids. |
| AID29306 | Neurotoxic dose (TD50) from horizontal screen in mice | 1991 | Journal of medicinal chemistry, Aug, Volume: 34, Issue:8
| Preparation and anticonvulsant activity of a series of functionalized alpha-heteroatom-substituted amino acids. |
| AID112157 | Effective dose required to prevent tonic extension of the hind limbs in mice in the maximal electroshock seizures (MES) test when administered intraperitoneally | 1994 | Journal of medicinal chemistry, Dec-23, Volume: 37, Issue:26
| Synthesis and anticonvulsant activities of alpha-acetamido-N-benzylacetamide derivatives containing an electron-deficient alpha-heteroaromatic substituent. |
| AID665966 | Neurotoxicity in ip dosed albino CF-1 mouse after 30 mins by rotorod test | 2012 | Bioorganic & medicinal chemistry, Jun-01, Volume: 20, Issue:11
| Synthesis, anticonvulsant activity, and neuropathic pain-attenuating activity of N-benzyl 2-amino-2-(hetero)aromatic acetamides. |
| AID480281 | Anticonvulsant activity in ip dosed albino mouse assessed as inhibition of maximal electroshock-induced seizures | 2010 | Journal of medicinal chemistry, May-13, Volume: 53, Issue:9
| Merging the structural motifs of functionalized amino acids and alpha-aminoamides: compounds with significant anticonvulsant activities. |
| AID665965 | Anticonvulsant activity in ip dosed albino CF-1 mouse assessed as protection against maximal electroshock-induced seizure after 0.5 hrs | 2012 | Bioorganic & medicinal chemistry, Jun-01, Volume: 20, Issue:11
| Synthesis, anticonvulsant activity, and neuropathic pain-attenuating activity of N-benzyl 2-amino-2-(hetero)aromatic acetamides. |
| AID136254 | Neurologic toxicity determined using horizontal screen test in mice | 1993 | Journal of medicinal chemistry, Oct-29, Volume: 36, Issue:22
| Synthesis and anticonvulsant activities of alpha-heterocyclic alpha-acetamido-N-benzylacetamide derivatives. |
| AID136259 | Neurological toxicity was determined using horizontal screen test in mice after intraperitoneal administration | 1990 | Journal of medicinal chemistry, Mar, Volume: 33, Issue:3
| Preparation and anticonvulsant activity of a series of functionalized alpha-aromatic and alpha-heteroaromatic amino acids. |
| AID226513 | Protective Index was determined using the ratio of TD50/ED50 value | 1994 | Journal of medicinal chemistry, Dec-23, Volume: 37, Issue:26
| Synthesis and anticonvulsant activities of alpha-acetamido-N-benzylacetamide derivatives containing an electron-deficient alpha-heteroaromatic substituent. |
| AID121859 | Median neurologically impairing dose was determined in mice using the rotarod test | 1994 | Journal of medicinal chemistry, Dec-23, Volume: 37, Issue:26
| Synthesis and anticonvulsant activities of alpha-acetamido-N-benzylacetamide derivatives containing an electron-deficient alpha-heteroaromatic substituent. |
| AID226521 | Protective index (TD50/ED50) | 1993 | Journal of medicinal chemistry, Oct-29, Volume: 36, Issue:22
| Synthesis and anticonvulsant activities of alpha-heterocyclic alpha-acetamido-N-benzylacetamide derivatives. |
| AID480287 | Toxicity in ip dosed albino mouse by rotarod test | 2010 | Journal of medicinal chemistry, May-13, Volume: 53, Issue:9
| Merging the structural motifs of functionalized amino acids and alpha-aminoamides: compounds with significant anticonvulsant activities. |
| AID113153 | Concentration required to prevent seizures upon intraperitoneal administration in mice in MES (maximal electroshock seizure) test. | 1991 | Journal of medicinal chemistry, Aug, Volume: 34, Issue:8
| Preparation and anticonvulsant activity of a series of functionalized alpha-heteroatom-substituted amino acids. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |