Page last updated: 2024-10-31

mirtazapine and Seizures

mirtazapine has been researched along with Seizures in 6 studies

Mirtazapine: A piperazinoazepine tetracyclic compound that enhances the release of NOREPINEPHRINE and SEROTONIN through blockage of presynaptic ALPHA-2 ADRENERGIC RECEPTORS. It also blocks both 5-HT2 and 5-HT3 serotonin receptors and is a potent HISTAMINE H1 RECEPTOR antagonist. It is used for the treatment of depression, and may also be useful for the treatment of anxiety disorders.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"We present a case of a patient who developed seizures shortly after initiating treatment with levofloxacin and to discuss the potential drug-drug interactions related to the inhibition of cytochrome P450 (CYP) 1A2 in this case, as well as in other cases, of levofloxacin-induced seizures."8.85Seizures associated with levofloxacin: case presentation and literature review. ( Bellon, A; Chacko, RC; Coverdale, JH; Perez-Garcia, G, 2009)
" We have investigated the effects of mirtazapine on pentylenetetrazole (PTZ)- and maximal electroconvulsive shock (MES)-induced seizures in mice."7.74Mirtazapine does not affect pentylenetetrazole- and maximal electroconvulsive shock-induced seizures in mice. ( Kayir, H; Sezer, Z; Uzbay, TI; Yilmaz, I, 2007)
"Mirtazapine was more effective than desipramine in restoring somatosensory cortex thickness by fully rescuing pyramidal neurons dendritic arborization and spine density."5.43Pharmacological treatment with mirtazapine rescues cortical atrophy and respiratory deficits in MeCP2 null mice. ( Baj, G; Bernareggi, A; Bittolo, T; Deiana, C; Ferrazzo, S; Raminelli, CA; Tongiorgi, E; Vaghi, V, 2016)
"We present a case of a patient who developed seizures shortly after initiating treatment with levofloxacin and to discuss the potential drug-drug interactions related to the inhibition of cytochrome P450 (CYP) 1A2 in this case, as well as in other cases, of levofloxacin-induced seizures."4.85Seizures associated with levofloxacin: case presentation and literature review. ( Bellon, A; Chacko, RC; Coverdale, JH; Perez-Garcia, G, 2009)
" We have investigated the effects of mirtazapine on pentylenetetrazole (PTZ)- and maximal electroconvulsive shock (MES)-induced seizures in mice."3.74Mirtazapine does not affect pentylenetetrazole- and maximal electroconvulsive shock-induced seizures in mice. ( Kayir, H; Sezer, Z; Uzbay, TI; Yilmaz, I, 2007)
"Mirtazapine was more effective than desipramine in restoring somatosensory cortex thickness by fully rescuing pyramidal neurons dendritic arborization and spine density."1.43Pharmacological treatment with mirtazapine rescues cortical atrophy and respiratory deficits in MeCP2 null mice. ( Baj, G; Bernareggi, A; Bittolo, T; Deiana, C; Ferrazzo, S; Raminelli, CA; Tongiorgi, E; Vaghi, V, 2016)
"Mirtazapine is a commonly prescribed antidepressant drug, which is also metabolized through and may modulate the CYP4502D6 pathway leading to altered metabolism of propafenone and possible adverse effects."1.40Propafenone associated severe central nervous system and cardiovascular toxicity due to mirtazapine: a case of severe drug interaction. ( Aryal, SR; Khan, MA; Rajpurohit, N; Stys, AT; Stys, TP, 2014)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rajpurohit, N1
Aryal, SR1
Khan, MA1
Stys, AT1
Stys, TP1
Bittolo, T1
Raminelli, CA1
Deiana, C1
Baj, G1
Vaghi, V1
Ferrazzo, S1
Bernareggi, A1
Tongiorgi, E1
Bellon, A1
Perez-Garcia, G1
Coverdale, JH1
Chacko, RC1
Brissos, S1
Palhavã, F1
Dias, VV1
Paiva, T1
Yilmaz, I1
Sezer, Z1
Kayir, H1
Uzbay, TI1
Zia Ul Haq, M1
Prakash, R1
Akhtar, S1

Reviews

1 review available for mirtazapine and Seizures

ArticleYear
Seizures associated with levofloxacin: case presentation and literature review.
    European journal of clinical pharmacology, 2009, Volume: 65, Issue:10

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Cytochrome

2009

Other Studies

5 other studies available for mirtazapine and Seizures

ArticleYear
Propafenone associated severe central nervous system and cardiovascular toxicity due to mirtazapine: a case of severe drug interaction.
    South Dakota medicine : the journal of the South Dakota State Medical Association, 2014, Volume: 67, Issue:4

    Topics: Aged; Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Atrial Fibrillation; Bradycardia; Di

2014
Pharmacological treatment with mirtazapine rescues cortical atrophy and respiratory deficits in MeCP2 null mice.
    Scientific reports, 2016, Jan-25, Volume: 6

    Topics: Animals; Antidepressive Agents; Atrophy; Breath Tests; Cerebral Cortex; Desipramine; GABAergic Neuro

2016
A case of crying seizures.
    The Journal of neuropsychiatry and clinical neurosciences, 2011,Winter, Volume: 23, Issue:1

    Topics: Adult; Crying; Female; Humans; Mianserin; Mirtazapine; Seizures

2011
Mirtazapine does not affect pentylenetetrazole- and maximal electroconvulsive shock-induced seizures in mice.
    Epilepsy & behavior : E&B, 2007, Volume: 11, Issue:1

    Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Chi-Square Distribution; Depressive

2007
Mirtazapine precipitated seizures: a case report.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, May-15, Volume: 32, Issue:4

    Topics: Anticonvulsants; Antidepressive Agents; Drug Interactions; Electroencephalography; Epilepsies, Parti

2008