pyruvaldehyde has been researched along with Seizures in 4 studies
Pyruvaldehyde: An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals.
methylglyoxal : A 2-oxo aldehyde derived from propanal.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We pretreated mice with MG before seizure induction with picrotoxin or pilocarpine and then assessed seizures behaviorally or by electroencephalography (EEG)." | 3.79 | Glyoxalase 1 and its substrate methylglyoxal are novel regulators of seizure susceptibility. ( Distler, MG; Escayg, A; Gorfinkle, N; Palmer, AA; Papale, LA; Termini, J; Winawer, MR; Wuenschell, GE, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Distler, MG | 2 |
| Gorfinkle, N | 1 |
| Papale, LA | 1 |
| Wuenschell, GE | 1 |
| Termini, J | 1 |
| Escayg, A | 1 |
| Winawer, MR | 1 |
| Palmer, AA | 2 |
| McMurray, KM | 1 |
| Sidhu, PS | 1 |
| Cook, JM | 1 |
| Arnold, LA | 1 |
| Plant, LD | 1 |
| Gasior, M | 2 |
| French, A | 1 |
| Joy, MT | 1 |
| Tang, RS | 1 |
| Hartman, AL | 2 |
| Rogawski, MA | 2 |
1 review available for pyruvaldehyde and Seizures
| Article | Year |
|---|---|
Glo1 inhibitors for neuropsychiatric and anti-epileptic drug development.
Topics: Animals; Anticonvulsants; Humans; Lactoylglutathione Lyase; Pyruvaldehyde; Seizures | 2014 |
3 other studies available for pyruvaldehyde and Seizures
| Article | Year |
|---|---|
Glyoxalase 1 and its substrate methylglyoxal are novel regulators of seizure susceptibility.
Topics: Animals; Anticonvulsants; Behavior, Animal; Databases, Genetic; Electroencephalography; Enzyme Inhib | 2013 |
The anticonvulsant activity of acetone, the major ketone body in the ketogenic diet, is not dependent on its metabolites acetol, 1,2-propanediol, methylglyoxal, or pyruvic acid.
Topics: Acetone; Animals; Anticonvulsants; Diet Therapy; Disease Models, Animal; Epilepsy; Ketone Bodies; Ma | 2007 |
The anticonvulsant activity of acetone does not depend upon its metabolites.
Topics: Acetone; Animals; Anticonvulsants; Blood-Brain Barrier; Disease Models, Animal; Humans; Injections, | 2008 |