Page last updated: 2024-11-06

palmitone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

palmitone: from leaves of Annona diversifolia; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

hentriacontan-16-one : A dialkyl ketone that is hentriacontane in which the hydrogens at position 16 are replaced by an oxo group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

FloraRankFlora DefinitionFamilyFamily Definition
AnnonagenusA plant genus of the family ANNONACEAE. It has edible fruit and seeds which contain acetogenins and benzoquinazoline and other alkaloids.[MeSH]AnnonaceaeThe custard-apple plant family of the order Magnoliales, subclass Magnoliidae, class Magnoliopsida. Some members provide large pulpy fruits and commercial timber. Leaves and wood are often fragrant. Leaves are simple, with smooth margins, and alternately arranged in two rows along the stems.[MeSH]

Cross-References

ID SourceID
PubMed CID94741
CHEBI ID5658
SCHEMBL ID352951
MeSH IDM0384354

Synonyms (31)

Synonym
CHEBI:5658
502-73-8
16-hentriacontanone
C08379
palmitone
nsc-953
nsc953 ,
hentriacontan-16-one
dipentadecyl ketone
pentadecyl ketone
H0423
LMFA12000005
hentricontan-16-one
hebtriacontanone
ai3-22025
nsc 953
unii-gr7i8ic3no
16-hentriacontane
16-hebtriacontanone
gr7i8ic3no ,
einecs 207-952-8
SCHEMBL352951
AKOS024390969
DTXSID00198239
mfcd00059222
FT-0736780
CS-0203837
Q27106854
D90862
AS-57185
A852531

Research Excerpts

Overview

Palmitone is a secondary metabolite of polyketide origin extracted from leaves of Annona diversifolia Saff.

ExcerptReferenceRelevance
"Palmitone is a secondary metabolite of polyketide origin extracted from leaves of Annona diversifolia Saff. "( Palmitone prevents pentylenetetrazole-caused neuronal damage in the CA3 hippocampal region of prepubertal rats.
Blas-Valdivia, V; Cano-Europa, E; González-Trujano, ME; Hernández-García, A; Ortiz-Butrón, R; Reyes-Ramírez, A, 2010
)
3.25

Actions

ExcerptReferenceRelevance
"Palmitone did not produce motor incoordination and loss of righting reflex which are used as signs of neurological impairment."( Anticonvulsant properties and bio-guided isolation of palmitone from leaves of Annona diversifolia.
Cedillo-Portugal, E; González-Trujano, ME; Hong, E; Navarrete, A; Reyes, B, 2001
)
1.28
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (2)

RoleDescription
metaboliteAny intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
anticonvulsantA drug used to prevent seizures or reduce their severity.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (1)

ClassDescription
dialkyl ketone
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (50.00)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 27.81

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index27.81 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index4.32 (4.65)
Search Engine Demand Index31.58 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (27.81)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]