tolbutamide has been researched along with Seizures in 13 studies
Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glipizide is a new hypoglycaemic sulphonylurea." | 1.25 | [Experimental study of glipizide. A comparison with other hypoglycemic sulfonamides (author's transl)]. ( Alric, R; Loubatières, AL; Loubatieres-Mariani, MM; Ribes, G; Sorial, G; Tarasco, A, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (84.62) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, J | 1 |
| O'Leary, EI | 1 |
| Tanner, GR | 1 |
| Stone, B | 1 |
| Evans, L | 1 |
| Coleman, J | 1 |
| Kuebler, D | 1 |
| LEHOTZKY, K | 1 |
| MESZAROS, I | 1 |
| TARDOS, L | 1 |
| COLES, HM | 1 |
| SOYKA, LF | 1 |
| MOLLIVER, M | 1 |
| CRAWFORD, JD | 1 |
| Loubatières, AL | 1 |
| Loubatieres-Mariani, MM | 1 |
| Alric, R | 1 |
| Ribes, G | 1 |
| Sorial, G | 1 |
| Tarasco, A | 1 |
| Etheridge, JE | 1 |
| Power, L | 1 |
| Yoshinaga, T | 1 |
| Isshiki, G | 1 |
| Okuno, G | 1 |
| Ueda, T | 1 |
| Ogawa, S | 1 |
| von Hattingberg, HM | 1 |
| Gladtke, E | 1 |
| Dost, FH | 1 |
| Hempel, HC | 1 |
| Hupfer, H | 1 |
| Grimm, J | 1 |
| Ambs, E | 1 |
| Brunnberg, J | 1 |
| Gekle, D | 1 |
| Giammanco, S | 1 |
| La Grutta, V | 1 |
| Cajola, G | 1 |
2 reviews available for tolbutamide and Seizures
| Article | Year |
|---|---|
Hypoglycemia and the central nervous system.
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Brain; Child, Preschool; Diazoxide; Diet Therapy; Epin | 1967 |
[The differential diagnosis of pathological carbohydrate tolerance].
Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus; Diagnosis, Differential; Fast | 1970 |
11 other studies available for tolbutamide and Seizures
| Article | Year |
|---|---|
The ketogenic diet metabolite beta-hydroxybutyrate (β-HB) reduces incidence of seizure-like activity (SLA) in a K
Topics: 3-Hydroxybutyric Acid; Animals; Animals, Genetically Modified; Anticonvulsants; Disease Models, Anim | 2017 |
Genetic and pharmacological manipulations that alter metabolism suppress seizure-like activity in Drosophila.
Topics: Animals; Animals, Genetically Modified; Carbon Dioxide; Disease Models, Animal; Disease Susceptibili | 2013 |
Central nervous effect of antidiabetic sulphonylurea compounds.
Topics: Central Nervous System; Humans; Hypoglycemic Agents; Nerve Tissue; Seizures; Sulfonylurea Compounds; | 1963 |
LEUCINE-SENSITIVE HYPOGLYCEMIA.
Topics: Glucose Tolerance Test; Humans; Hypoglycemia; Infant; Leucine; Metabolism; Methylprednisolone; Seizu | 1964 |
IDIOPATHIC HYPOGLYCAEMIA OF INFANCY TREATED WITH HUMAN GROWTH HORMONE.
Topics: Adrenocorticotropic Hormone; Genetics, Medical; Glucose Tolerance Test; Growth Hormone; Human Growth | 1964 |
[Experimental study of glipizide. A comparison with other hypoglycemic sulfonamides (author's transl)].
Topics: Administration, Oral; Ammonia; Animals; Dogs; Dose-Response Relationship, Drug; Female; Glipizide; G | 1975 |
A glucose-responsive insulinoma.
Topics: Adenoma, Islet Cell; Blood Glucose; Dietary Carbohydrates; Fasting; Glucose; Glucose Tolerance Test; | 1969 |
A-cell deficiency and B-cell hyperplasia of Langerhans' islet as a cause of leucine sensitive hypoglycemia.
Topics: Blood Glucose; Diazoxide; Epinephrine; Glucose Tolerance Test; Humans; Hyperplasia; Hypoglycemia; In | 1968 |
[Differential diagnosis and therapy of hypoglycemic seizures in childhood. A case of pancreas beta cell hyperplasia].
Topics: Child, Preschool; Diagnosis, Differential; Electroencephalography; Humans; Hypoglycemia; Infant; Inf | 1969 |
[Cerebral convulsion as symptom in spontaneous hypoglycemia in childhood].
Topics: Acetone; Adrenal Cortex Hormones; Blood Glucose; Child, Preschool; Diagnosis, Differential; Diet The | 1971 |
[Analysis of the spontaneous bioelectrical activity and of the excitability of the dorsal hippocampus in the rabbit with permanent electrodes, during hypoglycemia].
Topics: Animals; Electrophysiology; Hippocampus; Humans; Hypoglycemia; Insulin; Rabbits; Seizures; Tolbutami | 1967 |