Page last updated: 2024-11-05

tolbutamide and Seizures

tolbutamide has been researched along with Seizures in 13 studies

Tolbutamide: A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
tolbutamide : An N-sulfonylurea that consists of 1-butylurea having a tosyl group attached at the 3-position.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"Glipizide is a new hypoglycaemic sulphonylurea."1.25[Experimental study of glipizide. A comparison with other hypoglycemic sulfonamides (author's transl)]. ( Alric, R; Loubatières, AL; Loubatieres-Mariani, MM; Ribes, G; Sorial, G; Tarasco, A, 1975)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199011 (84.62)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, J1
O'Leary, EI1
Tanner, GR1
Stone, B1
Evans, L1
Coleman, J1
Kuebler, D1
LEHOTZKY, K1
MESZAROS, I1
TARDOS, L1
COLES, HM1
SOYKA, LF1
MOLLIVER, M1
CRAWFORD, JD1
Loubatières, AL1
Loubatieres-Mariani, MM1
Alric, R1
Ribes, G1
Sorial, G1
Tarasco, A1
Etheridge, JE1
Power, L1
Yoshinaga, T1
Isshiki, G1
Okuno, G1
Ueda, T1
Ogawa, S1
von Hattingberg, HM1
Gladtke, E1
Dost, FH1
Hempel, HC1
Hupfer, H1
Grimm, J1
Ambs, E1
Brunnberg, J1
Gekle, D1
Giammanco, S1
La Grutta, V1
Cajola, G1

Reviews

2 reviews available for tolbutamide and Seizures

ArticleYear
Hypoglycemia and the central nervous system.
    Pediatric clinics of North America, 1967, Volume: 14, Issue:4

    Topics: Adrenocorticotropic Hormone; Anticonvulsants; Brain; Child, Preschool; Diazoxide; Diet Therapy; Epin

1967
[The differential diagnosis of pathological carbohydrate tolerance].
    Deutsche medizinische Wochenschrift (1946), 1970, Feb-13, Volume: 95, Issue:7

    Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus; Diagnosis, Differential; Fast

1970

Other Studies

11 other studies available for tolbutamide and Seizures

ArticleYear
The ketogenic diet metabolite beta-hydroxybutyrate (β-HB) reduces incidence of seizure-like activity (SLA) in a K
    Epilepsy research, 2017, Volume: 133

    Topics: 3-Hydroxybutyric Acid; Animals; Animals, Genetically Modified; Anticonvulsants; Disease Models, Anim

2017
Genetic and pharmacological manipulations that alter metabolism suppress seizure-like activity in Drosophila.
    Brain research, 2013, Feb-16, Volume: 1496

    Topics: Animals; Animals, Genetically Modified; Carbon Dioxide; Disease Models, Animal; Disease Susceptibili

2013
Central nervous effect of antidiabetic sulphonylurea compounds.
    Acta physiologica Academiae Scientiarum Hungaricae, 1963, Volume: 23

    Topics: Central Nervous System; Humans; Hypoglycemic Agents; Nerve Tissue; Seizures; Sulfonylurea Compounds;

1963
LEUCINE-SENSITIVE HYPOGLYCEMIA.
    Proceedings of the Royal Society of Medicine, 1964, Volume: 57

    Topics: Glucose Tolerance Test; Humans; Hypoglycemia; Infant; Leucine; Metabolism; Methylprednisolone; Seizu

1964
IDIOPATHIC HYPOGLYCAEMIA OF INFANCY TREATED WITH HUMAN GROWTH HORMONE.
    Lancet (London, England), 1964, May-09, Volume: 1, Issue:7341

    Topics: Adrenocorticotropic Hormone; Genetics, Medical; Glucose Tolerance Test; Growth Hormone; Human Growth

1964
[Experimental study of glipizide. A comparison with other hypoglycemic sulfonamides (author's transl)].
    Diabete & metabolisme, 1975, Volume: 1

    Topics: Administration, Oral; Ammonia; Animals; Dogs; Dose-Response Relationship, Drug; Female; Glipizide; G

1975
A glucose-responsive insulinoma.
    JAMA, 1969, Feb-03, Volume: 207, Issue:5

    Topics: Adenoma, Islet Cell; Blood Glucose; Dietary Carbohydrates; Fasting; Glucose; Glucose Tolerance Test;

1969
A-cell deficiency and B-cell hyperplasia of Langerhans' islet as a cause of leucine sensitive hypoglycemia.
    Endokrinologie, 1968, Volume: 53, Issue:3

    Topics: Blood Glucose; Diazoxide; Epinephrine; Glucose Tolerance Test; Humans; Hyperplasia; Hypoglycemia; In

1968
[Differential diagnosis and therapy of hypoglycemic seizures in childhood. A case of pancreas beta cell hyperplasia].
    Monatsschrift fur Kinderheilkunde, 1969, Volume: 117, Issue:3

    Topics: Child, Preschool; Diagnosis, Differential; Electroencephalography; Humans; Hypoglycemia; Infant; Inf

1969
[Cerebral convulsion as symptom in spontaneous hypoglycemia in childhood].
    Medizinische Klinik, 1971, Jun-23, Volume: 66, Issue:30

    Topics: Acetone; Adrenal Cortex Hormones; Blood Glucose; Child, Preschool; Diagnosis, Differential; Diet The

1971
[Analysis of the spontaneous bioelectrical activity and of the excitability of the dorsal hippocampus in the rabbit with permanent electrodes, during hypoglycemia].
    Bollettino della Societa italiana di biologia sperimentale, 1967, Dec-15, Volume: 43, Issue:23

    Topics: Animals; Electrophysiology; Hippocampus; Humans; Hypoglycemia; Insulin; Rabbits; Seizures; Tolbutami

1967