imidazole has been researched along with Seizures in 6 studies
imidazole: RN given refers to parent cpd
1H-imidazole : An imidazole tautomer which has the migrating hydrogen at position 1.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effects of systemic injection of H3R ligands 1-13 on MES-induced and PTZ-kindled seizures were screened and evaluated against the reference antiepileptic drug (AED) Phenytoin (PHT) and the standard histamine H3R inverse agonist/antagonist Thioperamide (THP) to determine their potential as new antiepileptic drugs." | 3.79 | Anticonvulsant properties of histamine H3 receptor ligands belonging to N-substituted carbamates of imidazopropanol. ( Adem, A; Kieć-Kononowicz, K; Sadek, B; Shafiullah, M; Shehab, S; Subramanian, D; Więcek, M, 2013) |
| "The effects of new and potent NOS inhibitors, S-methyl-L-thiocitrulline (S-Me-TC), 3-bromo 7-nitro indazole (3-Br-7-NI), and 1-(2-trifluoromethylphenyl) imidazole (TRIM), were examined on the pilocarpine-induced seizures in mice." | 3.69 | Anticonvulsant activity of new and potent inhibitors of nitric oxide synthase. ( De Vries, R; Dzoljic, E; Dzoljic, MR, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sadek, B | 1 |
| Shehab, S | 1 |
| Więcek, M | 1 |
| Subramanian, D | 1 |
| Shafiullah, M | 1 |
| Kieć-Kononowicz, K | 1 |
| Adem, A | 1 |
| Szacoń, E | 1 |
| Rządkowska, M | 1 |
| Kaczor, AA | 1 |
| Kędzierska, E | 1 |
| Fidecka, S | 1 |
| Matosiuk, D | 1 |
| Karakurt, A | 1 |
| Ozalp, M | 1 |
| Işik, S | 1 |
| Stables, JP | 1 |
| Dalkara, S | 1 |
| ORDWAY, GL | 1 |
| PURO, HE | 1 |
| MARSH, C | 1 |
| MILLER, VJ | 1 |
| Dzoljic, E | 1 |
| De Vries, R | 1 |
| Dzoljic, MR | 1 |
6 other studies available for imidazole and Seizures
| Article | Year |
|---|---|
Anticonvulsant properties of histamine H3 receptor ligands belonging to N-substituted carbamates of imidazopropanol.
Topics: 1-Propanol; Animals; Anticonvulsants; Carbamates; Electroshock; Histamine Agonists; Histamine Antago | 2013 |
Synthesis, central nervous system activity and structure-activity relationships of novel 1-(1-Alkyl-4-aryl-4,5-dihydro-1H-imidazo)-3-substituted urea derivatives.
Topics: Animals; Behavior, Animal; Blood-Brain Barrier; Central Nervous System; Imidazoles; Locomotion; Male | 2015 |
Synthesis, anticonvulsant and antimicrobial activities of some new 2-acetylnaphthalene derivatives.
Topics: Animals; Anti-Infective Agents; Anticonvulsants; Crystallography, X-Ray; Imidazoles; Molecular Confo | 2010 |
Ketogenic and other derivatives of hydantoin as anticonvulsants; further results.
Topics: Anticonvulsants; Humans; Hydantoins; Imidazoles; Ketone Bodies; Seizures | 1949 |
Methyl-phenyl-ethyl hydantoin in the treatment of convulsive disorders.
Topics: Anticonvulsants; Hydantoins; Imidazoles; Seizures | 1949 |
Anticonvulsant activity of new and potent inhibitors of nitric oxide synthase.
Topics: Animals; Anticonvulsants; Citrulline; Disease Models, Animal; Enzyme Inhibitors; Imidazoles; Male; M | 1997 |