nortriptyline has been researched along with Seizures in 8 studies
Nortriptyline: A metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, and atypical depressions.
nortriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(methylamino)propylidene group at position 5. It is an active metabolite of amitriptyline.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The investigators studied a patient with a nortriptyline HCI level of 1,205 ng/mL who had four generalized grand mal seizures, each lasting between 60 and 90 seconds that were immediately followed by hypotension requiring norepinephrine support." | 7.69 | Recurrent hypotension immediately after seizures in nortriptyline overdose. ( Bell, A; Gaynor, B; Lipper, B, 1994) |
| " The investigators studied a patient with a nortriptyline HCI level of 1,205 ng/mL who had four generalized grand mal seizures, each lasting between 60 and 90 seconds that were immediately followed by hypotension requiring norepinephrine support." | 3.69 | Recurrent hypotension immediately after seizures in nortriptyline overdose. ( Bell, A; Gaynor, B; Lipper, B, 1994) |
| "Bupropion and tramadol were discontinued, and seizures did not recur." | 1.36 | Which xenobiotic(s) could be responsible for the radiologic findings below? Answer: any proconvulsant xenobiotic, in this case tramadol, bupropion, and nortriptyline. ( Roberts, DJ; Stellpflug, SJ, 2010) |
| " The actual dosing levels at the second treatment were compared with estimates based on HA." | 1.35 | Seizure threshold in a large sample: implications for stimulus dosing strategies in bilateral electroconvulsive therapy: a report from CORE. ( Bailine, S; Braga, RJ; Fink, M; Husain, M; Kellner, C; Knapp, R; Malur, C; Mueller, M; O'Connor, K; Petrides, G; Rummans, T, 2009) |
| " Increasing doses of nortriptyline produced a parallel shift of the hypothermic log dose-response curve for intraventricular injections of noradnamine to the right." | 1.25 | The interactions of noradnamine and imipramine-like antidepressant drugs. ( Cowell, P, 1969) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Özütemiz, C | 1 |
| Roshan, SK | 1 |
| Kroll, NJ | 1 |
| Rykken, JB | 1 |
| Ott, F | 1 |
| McKinney, AM | 1 |
| Petrides, G | 1 |
| Braga, RJ | 1 |
| Fink, M | 1 |
| Mueller, M | 1 |
| Knapp, R | 1 |
| Husain, M | 1 |
| Rummans, T | 1 |
| Bailine, S | 1 |
| Malur, C | 1 |
| O'Connor, K | 1 |
| Kellner, C | 1 |
| Stellpflug, SJ | 1 |
| Roberts, DJ | 1 |
| Lipper, B | 1 |
| Bell, A | 1 |
| Gaynor, B | 1 |
| Parkin, JM | 1 |
| Fraser, MS | 1 |
| Sedal, L | 1 |
| Korman, MG | 1 |
| Williams, PO | 1 |
| Mushin, G | 1 |
| Schuckit, M | 1 |
| Robins, E | 1 |
| Feighner, J | 1 |
| Cowell, P | 1 |
8 other studies available for nortriptyline and Seizures
| Article | Year |
|---|---|
Concomitant Acute Toxic Leukoencephalopathy and Posterior Reversible Encephalopathy Syndrome.
Topics: Adolescent; Adult; Aged; Drug Overdose; Female; Humans; Leukoencephalopathies; Magnetic Resonance Im | 2018 |
Seizure threshold in a large sample: implications for stimulus dosing strategies in bilateral electroconvulsive therapy: a report from CORE.
Topics: Aged; Aging; Antidepressive Agents, Tricyclic; Calibration; Depressive Disorder, Major; Dose-Respons | 2009 |
Which xenobiotic(s) could be responsible for the radiologic findings below? Answer: any proconvulsant xenobiotic, in this case tramadol, bupropion, and nortriptyline.
Topics: Adult; Analgesics, Opioid; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricycli | 2010 |
Recurrent hypotension immediately after seizures in nortriptyline overdose.
Topics: Biological Availability; Blood Pressure; Drug Overdose; Female; Heart; Humans; Hypotension; Midazola | 1994 |
Poisoning as a complication of enuresis.
Topics: Amitriptyline; Antidepressive Agents; Child, Preschool; Enuresis; Humans; Imipramine; Ipecac; Nortri | 1972 |
Overdosage of tricyclic antidepressants. A report of two deaths and a prospective study of 24 patients.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents; Arrhythmias, Cardiac; Bundle-Branch Block; | 1972 |
Tricyclic antidepressants and monoamine oxidase inhibitors.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amitriptyline; Animals; Depression; Desipramine; Drug | 1971 |
The interactions of noradnamine and imipramine-like antidepressant drugs.
Topics: Animals; Antidepressive Agents; Brain Chemistry; Cerebral Ventricles; Dibenzocycloheptenes; Hypother | 1969 |