proline and Seizures

proline has been researched along with Seizures in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199012 (38.71)18.7374
1990's5 (16.13)18.2507
2000's9 (29.03)29.6817
2010's5 (16.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Feng, YB; Han, YX; Lin, YT; Pang, YJ; Xu, JJ; Xue, Y; Yao, H1
Antinori, S; Cattaneo, D; Falvella, FS; Gervasoni, C; Magni, C; Milazzo, L; Peri, AM; Vidale, S1
Anderson, G; Benatti, M; Brown, R; Chong, K; Clayton, PT; Footitt, E; Gissen, P; Hemingway, C; Holden, S; James, C; Little, D; Mills, PB; Ocaka, L; Parker, A; Rahman, S; Reid, ES; Williams, H1
Bahlo, M; Cain, SM; David, LS; Foote, SJ; Garcia, E; Kyi, M; Ng, C; O'Brien, TJ; Powell, KL; Reid, CA; Sirdesai, S; Snutch, TP; Tyson, JR1
Druga, R; Folbergrová, J; Otáhal, J1
Chen, T; Corcoran, NM; Grundy, R; Hovens, CM; Jones, NC; Nguyen, T; O'Brien, TJ; Velakoulis, D1
Druga, R; Folbergrová, J; Haugvicová, R; Kubová, H; Mares, P; Otáhal, J1
Baumgartner, M; Baxter, P; Clayton, PT; Jakobs, C; Mills, PB; Omran, H; Plecko, B; Struys, E; Tacke, U; Uhlenberg, B; Weschke, B; Willemsen, MA1
Horton, RW; Prestwich, SA; Spyrou, NA1
Khudierkov, RM1
Cherkin, A; Davis, JL; Van Harreveld, A1
Bitner, RS; Isom, GE; Kanthasamy, A; Yim, GK1
Bond, A; Campbell, JB; Griffey, K; Howe, T; Johnson, BG; Lodge, D; Monn, JA; Paschal, JW; Salhoff, CR; Schoepp, DD; Spangle, LA; Tizzano, JP; Valli, MJ; Wright, RA1
Andersen, PH; Burns, CM; Chang, H; Crider, AM; el-Assadi, AA; Hinko, CN; Ho, B; Kliem, MA; Klitgaard, H; Seo, TH; Steinmiller, CL; Tietz, EI; Venkatarangan, P1
Bitner, RS; Isom, GE; Yim, GK1
Merton, WL; Mills, GA; Peters, SA; Walker, V1
Vivekanandan, S1
Matsumura, R1
Farrant, RD; Langley, GJ; Mellor, JM; Mills, GA; Walker, V1
Folbergrová, J; Haugvicová, R; Mares, P1
Kohn, H; LeTiran, A; Stables, JP1
Cherkin, A; Davis, JL; Eckardt, MJ; Gerbrandt, LK1
Cherkin, A; Davis, JL; Gerbrandt, LK1
Purkiss, P; Wajner, M; Wannmacher, CM1
Fleming, GA; Flynn, MP; Martin, MC; Moore, PT; Phang, JM; Stafford, JA1
Colton, CA; Colton, JS1
Beitz, AJ; Larson, AA1
Crider, AM; Hinko, CN; Wood, JD1
Alimov, IIu; Iur'eva, EA; Marchenko, ZM1
Blehová, B; Hyánek, J; Jirásek, J; Păzoutová, N1
Cann, HM; Fukanaga, K; Goldstein, AS; Hoogenraad, NJ; Johnson, JD; Sunshine, P; Swierczewski, E1

Reviews

1 review(s) available for proline and Seizures

ArticleYear
[Hyperprolinemia].
    Ryoikibetsu shokogun shirizu, 2000, Issue:29 Pt 4

    Topics: Amino Acid Metabolism, Inborn Errors; Biomarkers; delta-1-Pyrroline-5-Carboxylate Reductase; Diagnosis, Differential; Humans; Intellectual Disability; Proline; Pyrroline Carboxylate Reductases; Seizures

2000

Other Studies

30 other study(ies) available for proline and Seizures

ArticleYear
2R,4R-APDC, a Metabotropic Glutamate Receptor Agonist, Reduced Neuronal Apoptosis by Upregulating MicroRNA-128 in a Rat Model After Seizures.
    Neurochemical research, 2018, Volume: 43, Issue:3

    Topics: Animals; Animals, Newborn; Disease Models, Animal; Excitatory Amino Acid Agonists; Hippocampus; Male; Memory; MicroRNAs; Proline; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Seizures; Up-Regulation

2018
Seizures in patients with chronic hepatitis C treated with NS3/4A protease inhibitors: does pharmacological interaction play a role?
    Pharmacology, 2013, Volume: 92, Issue:5-6

    Topics: Adult; Antiviral Agents; Carrier Proteins; Drug Interactions; Follow-Up Studies; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Intracellular Signaling Peptides and Proteins; Male; Middle Aged; Oligopeptides; Polyethylene Glycols; Proline; Protease Inhibitors; Recombinant Proteins; Ribavirin; Seizures; Viral Nonstructural Proteins

2013
Mutations in SLC25A22: hyperprolinaemia, vacuolated fibroblasts and presentation with developmental delay.
    Journal of inherited metabolic disease, 2017, Volume: 40, Issue:3

    Topics: Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Developmental Disabilities; Female; Fibroblasts; Glutamic Acid; Humans; Infant; Infant, Newborn; Male; Mitochondria; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Muscle Hypotonia; Mutation; Proline; Seizures

2017
A Cav3.2 T-type calcium channel point mutation has splice-variant-specific effects on function and segregates with seizure expression in a polygenic rat model of absence epilepsy.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, Jan-14, Volume: 29, Issue:2

    Topics: Animals; Animals, Newborn; Arginine; Biophysics; Calcium Channels, T-Type; Cell Line, Transformed; Disease Models, Animal; Electric Stimulation; Electroencephalography; Epilepsy, Absence; Exons; Humans; In Vitro Techniques; Membrane Potentials; Models, Molecular; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Point Mutation; Proline; Protein Isoforms; Protein Structure, Tertiary; Rats; Rats, Transgenic; Seizures; Transfection

2009
Brain superoxide anion formation in immature rats during seizures: protection by selected compounds.
    Experimental neurology, 2012, Volume: 233, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Anticonvulsants; Brain; Disease Models, Animal; Homocysteine; Infusions, Intraventricular; Male; Metalloporphyrins; Proline; Rats; Rats, Wistar; Seizures; Statistics, Nonparametric; Superoxides; Time Factors

2012
Targeting hyperphosphorylated tau with sodium selenate suppresses seizures in rodent models.
    Neurobiology of disease, 2012, Volume: 45, Issue:3

    Topics: Amygdala; Analysis of Variance; Animals; Antioxidants; Cell Line, Tumor; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Gene Expression Regulation; Humans; Leucine; Male; Mutation; Neuroblastoma; Okadaic Acid; Pentylenetetrazole; Phosphorylation; Proline; Rats; Rats, Sprague-Dawley; Rats, Wistar; Seizures; Selenic Acid; Selenium Compounds; tau Proteins; Time Factors; Transfection

2012
Seizures induced in immature rats by homocysteic acid and the associated brain damage are prevented by group II metabotropic glutamate receptor agonist (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate.
    Experimental neurology, 2005, Volume: 192, Issue:2

    Topics: Amino Acids; Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Brain; Brain Chemistry; Brain Injuries; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Excitatory Amino Acid Antagonists; Fluoresceins; Fluorescent Dyes; Functional Laterality; Glucose; Glycogen; Homocysteine; Lactic Acid; Male; Nerve Degeneration; Organic Chemicals; Proline; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Seizures; Time Factors; Xanthenes

2005
Mutations in antiquitin in individuals with pyridoxine-dependent seizures.
    Nature medicine, 2006, Volume: 12, Issue:3

    Topics: Aldehyde Dehydrogenase; Animals; Bacterial Proteins; Child; Child, Preschool; CHO Cells; Cricetinae; Cricetulus; Exons; Heterozygote; Homozygote; Humans; Mutation; Oxidoreductases Acting on CH-NH Group Donors; Pipecolic Acids; Proline; Pyridoxal Phosphate; Pyridoxine; Seizures

2006
Synaptosomal [3H]GABA uptake and [3H]nipecotic acid binding in audiogenic seizure susceptible (DBA/2) and resistant (C57 B1/6) mice.
    European journal of pharmacology, 1984, Apr-20, Volume: 100, Issue:2

    Topics: Acoustic Stimulation; Age Factors; Animals; Cerebellum; Cerebral Cortex; gamma-Aminobutyric Acid; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nipecotic Acids; Pons; Proline; Seizures; Synaptosomes

1984
[Radioautographic study of protein synthesis in the neurons of the epileptogenic mirror focus in the rat brain. I. The stage of the occurrence of steady convulsive activity and the anterior parietal area of the cortex].
    Tsitologiia, 1982, Volume: 24, Issue:3

    Topics: Animals; Autoradiography; Epilepsies, Partial; Male; Nerve Tissue Proteins; Neurons; Parietal Lobe; Proline; Rats; Rats, Inbred Strains; Seizures; Thalamic Nuclei; Time Factors

1982
Amnestic potency of proline analogs correlates with anti-spreading depression potency.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 12, Issue:4

    Topics: Amnesia; Animals; Chickens; Cortical Spreading Depression; Glutamates; Glutamine; Humans; Hydroxyproline; Isoleucine; Pipecolic Acids; Proline; Retina; Seizures; Stereoisomerism

1980
Seizures and selective CA-1 hippocampal lesions induced by an excitotoxic cyanide metabolite, 2-iminothiazolidine-4-carboxylic acid.
    Neurotoxicology, 1995,Spring, Volume: 16, Issue:1

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Carboxylic Acids; Cyanides; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; Proline; Rats; Rats, Sprague-Dawley; Seizures

1995
Synthesis of the four isomers of 4-aminopyrrolidine-2,4-dicarboxylate: identification of a potent, highly selective, and systemically-active agonist for metabotropic glutamate receptors negatively coupled to adenylate cyclase.
    Journal of medicinal chemistry, 1996, Jul-19, Volume: 39, Issue:15

    Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Anticonvulsants; Cerebral Cortex; Colforsin; Cyclic AMP; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; Hydrogen Bonding; Limbic System; Mice; Models, Molecular; Molecular Structure; Proline; Rats; Receptors, Metabotropic Glutamate; Seizures; Spinal Cord; Stereoisomerism

1996
Anticonvulsant activity of novel derivatives of 2- and 3-piperidinecarboxylic acid in mice and rats.
    Neuropharmacology, 1996, Volume: 35, Issue:12

    Topics: 4-Aminopyridine; Amygdala; Animals; Anticonvulsants; Brain; Convulsants; Kindling, Neurologic; Male; Mice; Mice, Inbred Strains; Molecular Structure; N-Methylaspartate; Neurotoxins; Nipecotic Acids; Pentylenetetrazole; Pipecolic Acids; Proline; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Phencyclidine; Seizures; Structure-Activity Relationship; Valproic Acid

1996
2-Iminothiazolidine-4-carboxylic acid produces hippocampal CA1 lesions independent of seizure excitation and glutamate receptor activation.
    Neurotoxicology, 1997, Volume: 18, Issue:1

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain Ischemia; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Injections, Intraventricular; Male; Neuroprotective Agents; Neurotoxins; Proline; Rats; Rats, Sprague-Dawley; Seizures

1997
Fits, pyridoxine, and hyperprolinaemia type II.
    Archives of disease in childhood, 2000, Volume: 82, Issue:3

    Topics: Female; Genes, Recessive; Humans; Infant; Metabolic Diseases; Proline; Pyrroline Carboxylate Reductases; Seizures; Vitamin B 6 Deficiency

2000
Fits, pyridoxine, and hyperprolinaemia type II.
    Archives of disease in childhood, 2000, Volume: 83, Issue:1

    Topics: Cost-Benefit Analysis; Humans; Proline; Seizures; Transaminases; Vitamin B 6 Deficiency; Vitamin B Deficiency

2000
Pyridoxal phosphate de-activation by pyrroline-5-carboxylic acid. Increased risk of vitamin B6 deficiency and seizures in hyperprolinemia type II.
    The Journal of biological chemistry, 2001, May-04, Volume: 276, Issue:18

    Topics: Aldehydes; Avitaminosis; Chromatography, High Pressure Liquid; Humans; Ketones; Magnetic Resonance Spectroscopy; Mass Spectrometry; Proline; Pyridoxal Phosphate; Pyridoxine; Pyrroles; Seizures

2001
Attenuation of seizures induced by homocysteic acid in immature rats by metabotropic glutamate group II and group III receptor agonists.
    Brain research, 2001, Jul-27, Volume: 908, Issue:2

    Topics: Animals; Animals, Newborn; Anticonvulsants; Brain; Cyclobutanes; Cyclopropanes; Dose-Response Relationship, Drug; Epilepsy; Excitatory Amino Acid Agonists; Glycine; Homocysteine; Male; Neuroprotective Agents; Organophosphorus Compounds; Proline; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Seizures

2001
Functionalized amino acid anticonvulsants: synthesis and pharmacological evaluation of conformationally restricted analogues.
    Bioorganic & medicinal chemistry, 2001, Volume: 9, Issue:10

    Topics: Amino Acids; Animals; Anticonvulsants; Catalysis; Crystallography, X-Ray; Cyclization; Drug Design; Hydantoins; Lactams; Magnetic Resonance Spectroscopy; Male; Mice; Molecular Conformation; Molecular Structure; Neuroblastoma; Pentylenetetrazole; Phenobarbital; Phenytoin; Proline; Rats; Seizures; Sodium Channels; Stereoisomerism; Structure-Activity Relationship; Tetrazoles; Tumor Cells, Cultured

2001
Retrograde amnesia in neonatal chicks: induction by L-proline is not accompanied by occult seizures.
    Physiology & behavior, 1977, Volume: 19, Issue:6

    Topics: Amnesia; Amnesia, Retrograde; Animals; Animals, Newborn; Brain; Chickens; Convulsants; Electroencephalography; Humans; Injections, Intraventricular; Isoleucine; Male; Proline; Seizures

1977
Retroactive amnesia induced in chicks by the proline analog L-baikiain, without EEG seizures or depression.
    Physiology & behavior, 1978, Volume: 21, Issue:4

    Topics: Amnesia, Retrograde; Animals; Animals, Newborn; Chickens; Cortical Spreading Depression; Electroencephalography; Humans; Male; Memory; Proline; Seizures; Time Factors

1978
High urinary excretion of N-(pyrrole-2-carboxyl) glycine in type II hyperprolinemia.
    Clinical genetics, 1990, Volume: 37, Issue:6

    Topics: Amino Acid Metabolism, Inborn Errors; Consanguinity; Electroencephalography; Glycine; Growth Disorders; Humans; Infant; Male; Proline; Pyrroles; Recurrence; Seizures

1990
Type II hyperprolinaemia in a pedigree of Irish travellers (nomads).
    Archives of disease in childhood, 1989, Volume: 64, Issue:12

    Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Consanguinity; Female; Humans; Intellectual Disability; Ireland; Male; Oxidoreductases Acting on CH-NH Group Donors; Pedigree; Proline; Seizures; Transients and Migrants

1989
Blockade of hyperbaric oxygen induced seizures by excitatory amino acid antagonists.
    Canadian journal of physiology and pharmacology, 1985, Volume: 63, Issue:5

    Topics: 2-Amino-5-phosphonovalerate; 2-Aminoadipic Acid; Amino Acids; Animals; Anticonvulsants; Glutamates; Hyperbaric Oxygenation; Mice; Proline; Seizures; Valine

1985
Inhibition of intrathecally administered picrotoxin- and bicuculline-induced convulsions in mice by pipecolic acid or GABA.
    European journal of pharmacology, 1985, Aug-15, Volume: 114, Issue:2

    Topics: Animals; Bicuculline; gamma-Aminobutyric Acid; Injections, Spinal; Male; Mice; Nipecotic Acids; Picrotoxin; Pipecolic Acids; Proline; Receptors, GABA-A; Seizures; Strychnine

1985
A comparison of prodrug esters of nipecotic acid.
    Neuropharmacology, 1988, Volume: 27, Issue:5

    Topics: Animals; Anticonvulsants; Bicuculline; Esters; GABA Antagonists; Male; Mice; Nipecotic Acids; Parasympathomimetics; Pentylenetetrazole; Pharmaceutical Preparations; Prodrugs; Proline; Seizures; Strychnine

1988
[Amino acid metabolism pathology in the convulsive syndrome in young children].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1972, Volume: 72, Issue:10

    Topics: Alanine; Amino Acids; Arginine; Asparagine; Child, Preschool; Cystine; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Infant; Infant, Newborn; Leucine; Lysine; Male; Methionine; Proline; Seizures; Serine; Tryptophan; Tyrosine; Valine

1972
Iminoglycinuria in a child in Czechoslovakia.
    Humangenetik, 1973, Jul-20, Volume: 19, Issue:2

    Topics: Amino Acid Metabolism, Inborn Errors; Cerebrospinal Fluid Proteins; Deafness; Female; Glycine; Humans; Hydroxyproline; Infant; Intelligence; Intestinal Absorption; Male; Pedigree; Proline; Seizures; Time Factors

1973
Metabolic and genetic studies of a family with ornithine transcarbamylase deficiency.
    Pediatric research, 1974, Volume: 8, Issue:1

    Topics: Ammonia; Ammonium Chloride; Brain; Citrates; Dietary Proteins; Estradiol; Glucose; Heterozygote; Humans; Infant, Newborn; Intestines; Liver; Male; Metabolism, Inborn Errors; Ornithine Carbamoyltransferase; Orotic Acid; Pedigree; Peritoneal Dialysis; Phenobarbital; Proline; Seizures; Sex Factors

1974