diacetyl has been researched along with Seizures in 3 studies
butane-2,3-dione : An alpha-diketone that is butane substituted by oxo groups at positions 2 and 3. It is a metabolite produced during the malolactic fermentation.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "While adult mice receiving picrotoxin (PTX) alone responded with clonic and tonic-clonic seizures, this response was greatly suppressed for mice simultaneously injected with 2,3-butanedione monoxime (BDM)." | 3.69 | 2,3-Butanedione monoxime protects mice against the convulsant effect of picrotoxin by facilitating GABA-activated currents. ( Brightman, T; Flynn, EJ; McArdle, JJ; Ortiz-Jimenez, E; Wu, WH; Ye, JH, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shih, TM | 1 |
| Skovira, JW | 1 |
| O'Donnell, JC | 1 |
| McDonough, JH | 1 |
| Brightman, T | 1 |
| Ye, JH | 1 |
| Ortiz-Jimenez, E | 1 |
| Flynn, EJ | 1 |
| Wu, WH | 1 |
| McArdle, JJ | 1 |
| Stone, WE | 1 |
3 other studies available for diacetyl and Seizures
| Article | Year |
|---|---|
Treatment with tertiary oximes prevents seizures and improves survival following sarin intoxication.
Topics: Acetylcholinesterase; Animals; Atropine; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivato | 2010 |
2,3-Butanedione monoxime protects mice against the convulsant effect of picrotoxin by facilitating GABA-activated currents.
Topics: Animals; Anticonvulsants; Cholinesterase Reactivators; Diacetyl; Dose-Response Relationship, Drug; H | 1995 |
Effects of alterations in the metabolism of gamma-aminobutyrate on convulsant potencies.
Topics: 3-Mercaptopropionic Acid; Aminobutyrates; Aminooxyacetic Acid; Animals; Bicuculline; Diacetyl; Drug | 1977 |