hexamethonium has been researched along with Seizures in 4 studies
Hexamethonium: A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The tremorogenic effect of nicotine was studied in control rats and in rats withdrawn for 16-48 h from six to nine days' ethanol administration." | 7.67 | Ethanol withdrawal tremor potentiates the tremorogenic action of nicotine. ( Gothóni, P; Ikola, W, 1985) |
| "The tremorogenic effect of nicotine was studied in control rats and in rats withdrawn for 16-48 h from six to nine days' ethanol administration." | 3.67 | Ethanol withdrawal tremor potentiates the tremorogenic action of nicotine. ( Gothóni, P; Ikola, W, 1985) |
| "Seizures were produced by bicuculline or pentylenetetrazole." | 1.27 | Activation of a cranial vasodilator pathway during seizures in rats. ( Faraci, FM; Heistad, DD; Motley, MG, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| LAURENCE, DR | 1 |
| STACEY, RS | 1 |
| SHARLAI, RI | 1 |
| POCHEPTSOV, VG | 1 |
| GRANOVSKAIA, SE | 1 |
| KOZLOVA, OM | 1 |
| Gothóni, P | 1 |
| Ikola, W | 1 |
| Faraci, FM | 1 |
| Motley, MG | 1 |
| Heistad, DD | 1 |
4 other studies available for hexamethonium and Seizures
| Article | Year |
|---|---|
Mechanism of the prevention of nicotine convulsions by hexamethonium and by adrenaline blocking agents.
Topics: Adrenal Glands; Biomedical Research; Colorimetry; Epinephrine; Hexamethonium; Humans; Muscle Relaxan | 1953 |
[On the effect of hexonium in seizures of renal colic].
Topics: Hexamethonium; Humans; Renal Colic; Seizures; Urinary Calculi | 1959 |
Ethanol withdrawal tremor potentiates the tremorogenic action of nicotine.
Topics: Animals; Ethanol; Hexamethonium; Hexamethonium Compounds; Male; Nicotine; Propranolol; Rats; Rats, I | 1985 |
Activation of a cranial vasodilator pathway during seizures in rats.
Topics: Animals; Atropine; Bicuculline; Cerebrovascular Circulation; Hexamethonium; Hexamethonium Compounds; | 1986 |