Page last updated: 2024-08-21

quinazolines and Seizures

quinazolines has been researched along with Seizures in 43 studies

Research

Studies (43)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (30.23)	18.7374
1990's	3 (6.98)	18.2507
2000's	10 (23.26)	29.6817
2010's	16 (37.21)	24.3611
2020's	1 (2.33)	2.80

Authors

Authors	Studies
Danzer, SC; Gross, C; MacLeod, MC; Tiwari, D; White, AR	1
Amini, E; Faraj, FL; Gholami, K; Golpich, M; Rothan, HA; Teoh, TC; Yusof, R	1
A Maklad, Y; Abuelizz, HA; Al-Salahi, R; Anouar, EH; Dib, RE; Marzouk, M; N Attia, H	1
Ahn, JO; Chung, JY; Jaung, WJ; Jeon, KO; Ryu, MO; Song, WJ; Won, SH; Youn, HY	1
Fujita, K; Kitami, Y; Miyama, S; Nagai, Y; Takei, H	1
Madaiah, M; Prashanth, MK; Revanasiddappa, HD; Veeresh, B	1
Abbas, Sel-S; Awadallah, FM; Ibrahim, NA; Kamel, G; Said, EG	1
Bahare, RS; Khan, SA; Malik, S	1
Deepakumari, HN; Jayanna, BK; Prashanth, MK; Revanasiddappa, HD; Veeresh, B	1
Bari, SB; Ugale, VG	1
Catarzi, D; Colotta, V; Filacchioni, G; Lenzi, O; Lingenhöhl, K; Ofner, S; Poli, D; Varano, F	1
El-Azab, AS; Eltahir, KE	2
Akazawa, Y; Imamura, F; Kumagai, T; Nishino, K; Okyuama, T; Uchida, J	1
Bari, SB; Patel, HM; Shirkhedkar, AA; Surana, SJ; Ugale, VG; Wadodkar, SG	1
Bian, M; Deng, XQ; Quan, ZS; Wang, SB; Zheng, Y	1
Ali, I; Amir, M; Hassan, MZ	1
Kumar, A; Srivastava, VK	2
Buchan, AM; Chenard, BL; Critchett, DJ; Ganong, AH; Guanowsky, V; Menniti, FS; Seymour, PA; Welch, WM	1
De Micheli, C; De Sarro, G; Ferreri, G; Grasso, S; Menniti, FS; Micale, N; Zappalà, M; Zuccalà, G	1
Kingston, AE; Peters, SC; Shannon, HE	1
De Sarro, G; Ferreri, G; Grasso, S; Micale, N; Postorino, G; Zappalà, M; Zuccalà, G	1
Gabizon, A; Gipps, M; Grenader, T; Shavit, L	1
Blanton, CD; Fatmi, AA; Iturrian, WB; Vaidya, NA	1
Blanton, CD; Iturrian, WB; Kite, A; Panos, CH; Vaidya, NA	1
Mohan Rao, VK; Prasad, CR; Sethi, U	1
Chaudhari, A; Dwivedi, C; Misra, RS; Parmar, SS	1
el-Feky, SA	1
Hansen, HC; Jackson, HC; Judge, ME; Klitgaard, H; Kristiansen, M; Suzdak, PD; Swedberg, MD	1
Ebert, U; Hönack, D; Löscher, W; Rundfeldt, C	1
Scriba, GK; Usifoh, CO	1
Chenard, BL; Critchett, D; DeVries, KM; Ewing, FE; Ganong, AH; Guanowsky, V; Guhan, S; Guinn, MR; Huang, J; Kelly, K; Lazzaro, J; Menniti, FS; Pagnozzi, MJ; Seymour, PA; Staigers, TL; Welch, WM	1
Kardos, J; Kovács, R; Lasztóczi, B; Nyikos, L	1
Baumann, N; Chermat, R; Lachapelle, F; Simon, P	1
Brumleve, SJ; Chaturvedi, AK; Chaudhary, A; Parmar, SS	1
Malhotra, CL; Mehta, VL	1
Fryer, RI; Walser, A	1
Ali, B; Gupta, TK; Kumar, R; Parmar, SS	1
Combs, G; Diamond, L; Glasser, AC	1
Chatterjee, BK; Dey, PK	1
Bhaduri, AP; Gupta, CM; Khanna, NM	1
Kobayashi, K; Mizuno, A; Mori, A; Mukawa, J; Okusu, H	1

Other Studies

43 other study(ies) available for quinazolines and Seizures

Article	Year
PI3K isoform-selective inhibition in neuron-specific PTEN-deficient mice rescues molecular defects and reduces epilepsy-associated phenotypes. Neurobiology of disease, 2020, Volume: 144 Topics: Adenine; Animals; Cerebral Cortex; Class I Phosphatidylinositol 3-Kinases; Epilepsy; Female; Hippocampus; Male; Megalencephaly; Mice; Neurons; Phosphoinositide-3 Kinase Inhibitors; PTEN Phosphohydrolase; Quinazolines; Seizures; Thiazoles	2020
NMDA receptor antagonism with novel indolyl, 2-(1,1-Dimethyl-1,3-dihydro-benzo[e]indol-2-ylidene)-malonaldehyde, reduces seizures duration in a rat model of epilepsy. Scientific reports, 2017, 03-30, Volume: 7 Topics: Animals; Anticonvulsants; Disease Models, Animal; Epilepsy; Hippocampus; Indoles; Male; Malondialdehyde; Molecular Docking Simulation; Protein Binding; Quinazolines; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures	2017
Molecular Docking and Anticonvulsant Activity of Newly Synthesized Quinazoline Derivatives. Molecules (Basel, Switzerland), 2017, Jun-30, Volume: 22, Issue:7 Topics: Animals; Anticonvulsants; Disease Models, Animal; Humans; Male; Mice; Molecular Docking Simulation; Molecular Dynamics Simulation; Quinazolines; Seizures; Structure-Activity Relationship	2017
Accidental afloqualone intoxication in two dogs. The Journal of veterinary medical science, 2018, Feb-02, Volume: 80, Issue:1 Topics: Animals; Ataxia; Bradycardia; Dog Diseases; Dogs; Flumazenil; Male; Quinazolines; Respiratory Insufficiency; Seizures; Vomiting	2018
Coma and seizure caused by an afloqualone overdose. Pediatrics international : official journal of the Japan Pediatric Society, 2019, Volume: 61, Issue:2 Topics: Child, Preschool; Coma; Drug Overdose; Female; Humans; Muscle Relaxants, Central; Quinazolines; Seizures	2019
Synthesis, anticonvulsant, antioxidant and binding interaction of novel N-substituted methylquinazoline-2,4(1H,3H)-dione derivatives to bovine serum albumin: a structure-activity relationship study. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2013, Volume: 110 Topics: Animals; Anticonvulsants; Antioxidants; Binding Sites; Biphenyl Compounds; Cattle; Mice; Picrates; Protein Binding; Quinazolines; Seizures; Serum Albumin, Bovine; Spectrometry, Fluorescence; Structure-Activity Relationship; Superoxides	2013
Design and synthesis of some 3-substituted-2-[(2,4-dichlorophenoxy)-methyl]quinazolin-4(3H)-one derivatives as potential anticonvulsant agents. Chemical & pharmaceutical bulletin, 2013, Volume: 61, Issue:7 Topics: Animals; Anticonvulsants; Disease Models, Animal; Drug Design; Female; Hydrazines; Lethal Dose 50; Male; Mice; Neurons; Pentylenetetrazole; Quinazolines; Quinazolinones; Seizures; Triazines	2013
Design, synthesis and anticonvulsant evaluation of N-(benzo[d]thiazol-2-ylcarbamoyl)-2-methyl-4-oxoquinazoline-3(4H)-carbothioamide derivatives: a hybrid pharmacophore approach. European journal of medicinal chemistry, 2013, Volume: 67 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Disease Models, Animal; Drug Design; Electroshock; Injections, Intraperitoneal; Mice; Molecular Structure; Quinazolines; Rats; Rats, Wistar; Seizures; Thiazoles; Thioamides	2013
Synthesis and Anticonvulsant Activity of N-(Substituted)-1-methyl-2,4-dioxo-1,2-dihydroquinazoline-3(4H)-carboxamides. Archiv der Pharmazie, 2016, Volume: 349, Issue:7 Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Methaqualone; Mice; Pentylenetetrazole; Picrotoxin; Quinazolines; Seizures; Structure-Activity Relationship; Valproic Acid	2016
Structural Exploration of Quinazolin-4(3H)-ones as Anticonvulsants: Rational Design, Synthesis, Pharmacological Evaluation, and Molecular Docking Studies. Archiv der Pharmazie, 2016, Volume: 349, Issue:11 Topics: Acetamides; Animals; Anticonvulsants; Computer Simulation; Dose-Response Relationship, Drug; Drug Design; Electroshock; Mice; Molecular Docking Simulation; Molecular Structure; Pentylenetetrazole; Quinazolines; Seizures; Structure-Activity Relationship	2016
Pharmacological characterization of some selected 4,5-dihydro-4-oxo-1,2,4-triazolo[1,5-a]quinoxaline-2-carboxylates and 3-hydroxyquinazoline-2,4-diones as (S)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)-propionic acid receptor antagonists. Chemical & pharmaceutical bulletin, 2010, Volume: 58, Issue:7 Topics: Animals; Anticonvulsants; Mice; Oocytes; Quinazolines; Quinoxalines; Rats; Receptors, AMPA; Seizures	2010
Synthesis and anticonvulsant evaluation of some new 2,3,8-trisubstituted-4(3H)-quinazoline derivatives. Bioorganic & medicinal chemistry letters, 2012, Jan-01, Volume: 22, Issue:1 Topics: Animals; Anticonvulsants; Chemistry, Pharmaceutical; Drug Design; Humans; Male; Methaqualone; Mice; Models, Chemical; Nervous System; Quinazolines; Seizures; Valproic Acid	2012
Design and synthesis of novel 7-aminoquinazoline derivatives: antitumor and anticonvulsant activities. Bioorganic & medicinal chemistry letters, 2012, Mar-01, Volume: 22, Issue:5 Topics: Amines; Animals; Anticonvulsants; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Humans; Mice; Neoplasms; Quinazolines; Seizures	2012
Subacute transient encephalopathy induced by erlotinib. Oncology research, 2011, Volume: 19, Issue:8-9 Topics: Aged; Carcinoma, Non-Small-Cell Lung; Central Nervous System Diseases; Confusion; Erlotinib Hydrochloride; Female; Humans; Irritable Mood; Lethargy; Lung Neoplasms; Protein Kinase Inhibitors; Quinazolines; Seizures; Unconsciousness; Urinary Incontinence	2011
Quinazolino-benzothiazoles: fused pharmacophores as anticonvulsant agents. European journal of medicinal chemistry, 2012, Volume: 53 Topics: Animals; Anticonvulsants; Benzothiazoles; Drug Design; Electroshock; Male; Mice; Pentylenetetrazole; Quinazolines; Seizures	2012
Synthesis and anticonvulsant activity evaluation of 5-phenyl-[1,2,4]triazolo[4,3-c]quinazolin-3-amines. Archiv der Pharmazie, 2013, Volume: 346, Issue:2 Topics: Amines; Animals; Anticonvulsants; Drug Design; Electroshock; Mice; Mice, Inbred Strains; Molecular Structure; Neurotoxicity Syndromes; Quinazolines; Rotarod Performance Test; Seizures; Triazoles	2013
Design and synthesis of some new quinazolin-4-(3H)-ones as anticonvulsant and antidepressant agents. Archives of pharmacal research, 2013, Volume: 36, Issue:1 Topics: Animals; Anticonvulsants; Antidepressive Agents; Brain; Disease Models, Animal; Drug Design; gamma-Aminobutyric Acid; Mice; Molecular Structure; Quinazolines; Seizures; Structure-Activity Relationship; Swimming	2013
Synthesis of newer thiadiazolyl and thiazolidinonyl quinazolin-4 3H-ones as potential anticonvulsant agents. European journal of medicinal chemistry, 2002, Volume: 37, Issue:11 Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Pentobarbital; Quinazolines; Rats; Rats, Inbred Strains; Seizures; Sleep; Structure-Activity Relationship; Thiadiazoles	2002
CP-465,022, a selective noncompetitive AMPA receptor antagonist, blocks AMPA receptors but is not neuroprotective in vivo. Stroke, 2003, Volume: 34, Issue:1 Topics: Animals; Brain Ischemia; Hippocampus; Male; Motor Activity; Neuroprotective Agents; Pentylenetetrazole; Quinazolines; Rats; Receptors, AMPA; Seizures; Synaptic Transmission	2003
1-aryl-6,7-methylenedioxy-3H-quinazolin-4-ones as anticonvulsant agents. Bioorganic & medicinal chemistry letters, 2003, Dec-15, Volume: 13, Issue:24 Topics: Acoustic Stimulation; Animals; Anticonvulsants; Benzodiazepines; Drug Design; Mice; Models, Molecular; Quinazolines; Seizures; Structure-Activity Relationship	2003
Synthesis of some newer derivatives of substituted quinazolinonyl-2-oxo/thiobarbituric acid as potent anticonvulsant agents. Bioorganic & medicinal chemistry, 2004, Mar-01, Volume: 12, Issue:5 Topics: Animals; Anticonvulsants; Conscious Sedation; Exploratory Behavior; Hypnosis; Motor Activity; Quinazolines; Rats; Seizures; Sleep; Thiobarbiturates	2004
Anticonvulsant effects of LY456236, a selective mGlu1 receptor antagonist. Neuropharmacology, 2005, Volume: 49 Suppl 1 Topics: Acoustic Stimulation; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Excitatory Amino Acid Antagonists; Male; Mice; Mice, Inbred DBA; Pentylenetetrazole; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Seizures; Sensory Thresholds; Time Factors	2005
Synthesis of novel 3-(alkylcarbamoyl)-2-aryl-1,2-dihydro-6,7-(methylenedioxy)-3H-quinazolin-4-ones as anticonvulsant agents. Chemistry & biodiversity, 2006, Volume: 3, Issue:3 Topics: Animals; Anticonvulsants; Drugs, Investigational; Mice; Mice, Inbred DBA; Protein Binding; Quinazolines; Rats; Seizures	2006
Significant drug interaction: phenytoin toxicity due to erlotinib. Lung cancer (Amsterdam, Netherlands), 2007, Volume: 57, Issue:3 Topics: Anticonvulsants; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Drug Interactions; Erlotinib Hydrochloride; Fatal Outcome; Female; Humans; Lung Neoplasms; Middle Aged; Phenytoin; Protein Kinase Inhibitors; Quinazolines; Seizures	2007
Synthesis of previously inaccessible quinazolines and 1,4-benzodiazepines as potential anticonvulsants. Journal of medicinal chemistry, 1984, Volume: 27, Issue:6 Topics: Animals; Anticonvulsants; Benzodiazepines; Mice; Pentylenetetrazole; Quinazolines; Receptors, Cell Surface; Receptors, GABA-A; Seizures	1984
Synthesis of 3,4-dihydro-4-oxoquinazoline derivatives as potential anticonvulsants. Journal of medicinal chemistry, 1983, Volume: 26, Issue:10 Topics: Animals; Anticonvulsants; Drug Evaluation, Preclinical; Electroshock; Magnetic Resonance Spectroscopy; Male; Mice; Pentylenetetrazole; Quinazolines; Seizures; Spectrophotometry, Infrared; Structure-Activity Relationship	1983
Drug interactions between centazolone & some centrally acting agents. Indian journal of experimental biology, 1981, Volume: 19, Issue:3 Topics: Amphetamine; Animals; Drug Interactions; Pentylenetetrazole; Quinazolines; Rats; Seizures; Strychnine; Tranquilizing Agents	1981
Correlation between monoamine oxidase inhibitors and anticonvulsants. Journal of the National Medical Association, 1980, Volume: 72, Issue:10 Topics: Animals; Anticonvulsants; Male; Mice; Monoamine Oxidase Inhibitors; Quinazolines; Seizures; Structure-Activity Relationship	1980
Synthesis and anticonvulsant properties of some novel quinazolinone thiazolidine and 4-thiazolidone derivatives. Die Pharmazie, 1993, Volume: 48, Issue:12 Topics: Animals; Anticonvulsants; Female; Male; Mice; Pentylenetetrazole; Quinazolines; Seizures; Spectrophotometry, Infrared; Thiazoles	1993
Anticonvulsant profile of the imidazoquinazolines NNC 14-0185 and NNC 14-0189 in rats and mice. European journal of pharmacology, 1996, Jul-11, Volume: 308, Issue:1 Topics: Acoustic Stimulation; Amygdala; Animals; Anticonvulsants; Bicuculline; Carbolines; Clonazepam; Diazepam; Electroshock; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; Kindling, Neurologic; Male; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Pentylenetetrazole; Quinazolines; Rats; Rats, Wistar; Seizures	1996
Long-term studies on anticonvulsant tolerance and withdrawal characteristics of benzodiazepine receptor ligands in different seizure models in mice. II. The novel imidazoquinazolines NNC 14-0185 and NNC 14-0189. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:2 Topics: Animals; Anticonvulsants; Body Temperature; Drug Tolerance; GABA-A Receptor Agonists; Male; Mice; Motor Activity; Quinazolines; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders	1996
Synthesis and anticonvulsant activity of acetylenic quinazolinone derivatives. Archiv der Pharmazie, 2000, Volume: 333, Issue:8 Topics: Acetylene; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Ketones; Male; Mice; Quinazolines; Seizures	2000
Atropisomeric quinazolin-4-one derivatives are potent noncompetitive alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonists. Bioorganic & medicinal chemistry letters, 2001, Jan-22, Volume: 11, Issue:2 Topics: Animals; Anticonvulsants; Binding, Competitive; Brain; Calcium; Disease Models, Animal; Inhibitory Concentration 50; Isomerism; Neuromuscular Blocking Agents; Protein Binding; Pyridines; Quinazolines; Quinazolinones; Rats; Receptors, AMPA; Seizures; Solubility; Structure-Activity Relationship; Synaptic Transmission	2001
A glutamate receptor subtype antagonist inhibits seizures in rat hippocampal slices. Neuroreport, 2002, Mar-04, Volume: 13, Issue:3 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Anticonvulsants; Electrophysiology; Excitatory Amino Acid Antagonists; In Vitro Techniques; Magnesium; Male; Membrane Potentials; Piperidines; Quinazolines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Seizures	2002
Anticonvulsant effect of yohimbine in quaking mice: antagonism by clonidine and prazosine. Life sciences, 1979, Oct-22, Volume: 25, Issue:17 Topics: Animals; Anticonvulsants; Clonidine; Male; Mice; Mice, Quaking; Phentolamine; Prazosin; Quinazolines; Seizures; Yohimbine	1979
Substituted piperazinoquinazolones: relationship between selective inhibition of nicotinamide adenine dinucleotide-dependent oxidations and anticonvulsant activity. Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:3 Topics: Animals; Anticonvulsants; Brain; Citrates; Hydroxybutyrates; In Vitro Techniques; Isocitrates; Ketoglutaric Acids; Male; NAD; ortho-Aminobenzoates; Oxidation-Reduction; Pentylenetetrazole; Piperazines; Pyruvates; Quinazolines; Rats; Seizures; Structure-Activity Relationship	1974
Anticonvulsant and some neuropharmacological properties of 2-methyl-3-omicron-tolyl-6-chloro-4(3h)-quinazolone and related compounds. The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:8 Topics: Analgesics; Animals; Anticonvulsants; Behavior, Animal; Body Temperature; Central Nervous System; Drug Synergism; Electric Stimulation; Electrophysiology; Hypnotics and Sedatives; Mice; Pentylenetetrazole; Quinazolines; Rats; Seizures; Sleep	1966
Quinazolines and 1,4-benzodiazepines. 69. 1-Vinyl-1,4-benzodiazepin-2-ones and 1-vinylquinazolin-2(1H)-ones. Journal of medicinal chemistry, 1974, Volume: 17, Issue:11 Topics: Animals; Benzodiazepinones; Central Nervous System; Chlordiazepoxide; Depression, Chemical; Diazepam; Flurazepam; Lethal Dose 50; Mice; Pentylenetetrazole; Quinazolines; Seizures; Vinyl Compounds	1974
Relationship between CNS depressant activity and selective enzyme inhibition by quinazolone salicylhydrazide derivatives. Japanese journal of pharmacology, 1973, Volume: 23, Issue:1 Topics: Animals; Anticonvulsants; Brain; Drug Synergism; Electroconvulsive Therapy; Hydrazines; Hypnotics and Sedatives; In Vitro Techniques; Mice; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Pentobarbital; Pentylenetetrazole; Pyruvates; Quinazolines; Salicylates; Seizures; Structure-Activity Relationship; Succinates	1973
Synthesis and anticonvulsant activity of substituted 2-thioquinazolin-4-ones. I. Preliminary studies. Journal of pharmaceutical sciences, 1971, Volume: 60, Issue:1 Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry; Electroshock; Male; Mice; Pentylenetetrazole; Phenobarbital; Phenytoin; Quinazolines; Seizures	1971
Effect of glycosine on the higher nervous activity. Die Naturwissenschaften, 1967, Volume: 54, Issue:1 Topics: Animals; Anticonvulsants; Blood Pressure; Cocaine; Depression, Chemical; Heart; Higher Nervous Activity; Mescaline; Mice; Muscle Contraction; Pentylenetetrazole; Quinazolines; Seizures; Strychnine; Thiopental	1967
Drugs acting on the central nervous system. Syntheses of substituted quinazolones and quinazolines and triazepino- and triazocinoquinazolones. Journal of medicinal chemistry, 1968, Volume: 11, Issue:2 Topics: Animals; Azepines; Central Nervous System; Chemical Phenomena; Chemistry, Physical; Depression, Chemical; Electroshock; Ketones; Mice; Quinazolines; Seizures; Stimulation, Chemical	1968
[Metabolism and anti-convulsive action of 2-[beta-pyridyl-(2")-ethenyl]-3-(2'-methylphenyl)-quinazolinone-(4) (B169)]. No to shinkei = Brain and nerve, 1969, Volume: 21, Issue:3 Topics: Animals; Anticonvulsants; Brain; Cats; Cerebral Cortex; Electroencephalography; Feces; Female; Hippocampus; Injections, Intraperitoneal; Injections, Intravenous; Kidney; Liver; Lung; Mice; Myocardium; Quinazolines; Rabbits; Seizures; Spleen; Tritium	1969