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hydroxyindoleacetic acid and Seizures

hydroxyindoleacetic acid has been researched along with Seizures in 74 studies

(5-hydroxyindol-3-yl)acetic acid : A member of the class of indole-3-acetic acids that is indole-3-acetic acid substituted by a hydroxy group at C-5.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"Systemic injection of pilocarpine has been shown to induce recurrent seizures and epileptic discharges demonstrated by EEG monitoring."7.76Lipoic acid effects on monoaminergic system after pilocarpine-induced seizures. ( Feng, D; Freitas, RM; Jordán, J, 2010)
" In the present study we performed parallel measurements of BDNF mRNA and protein expression in the frontal cortex and hippocampus of the rat after chronic treatment with electroconvulsive seizures (ECS), lithium, desipramine or escitalopram."7.72The effect of escitalopram, desipramine, electroconvulsive seizures and lithium on brain-derived neurotrophic factor mRNA and protein expression in the rat brain and the correlation to 5-HT and 5-HIAA levels. ( Jacobsen, JP; Mørk, A, 2004)
"The effects of fluoxetine [an inhibitor of 5-hydroxytryptamine (5-HT) reuptake] on electrically-induced spinal cord seizures were determined by monitoring alterations in the total duration of seizure, as well as the durations of tonic flexion and extension."7.66Effects of fluoxetine on electrically-induced spinal cord seizures in rats. ( Jobe, PC; Ray, TB; Woods, TW, 1980)
"The relationships between behavioral responses and levels of serotonin (5-HT) and 5-hydroxyindoleacetic acid (5-HIAA) in brain of mice were investigated after intravenous injection of fumitremorgin A (FTA)."7.66Biochemical investigation on the abnormal behaviors induced by fumitremorgin A, a tremorgenic mycotoxin to mice. ( Ozaki, N; Suzuki, S; Yamazaki, M, 1983)
"Little is known about 5-hydroxyindolacetic acid (5-HIAA) and homovanillic acid (HVA) levels in cerebrospinal fluid of patients with Delirium Tremens revealed at onset by seizures."5.105-Hydroxyindolacetic acid and homovanillic acid are not involved in the cerebrospinal fluid after a seizure in patients with Delirium Tremens. ( Beley, P; Couvreur, G; Demougeot, C; Giroud, M; Marie, C; Maugras, C, 2002)
"The experimental model of seizures which depends upon methionine sulfoximine (MSO) simulates the most striking form of human epilepsy."3.79Monoamines and glycogen levels in cerebral cortices of fast and slow methionine sulfoximine-inbred mice. ( Boissonnet, A; Cloix, JF; Hévor, T; Landemarre, L, 2013)
"The aim of this work was to analyze the effect of oxcarbazepine (OXC) on sleep patterns, "head and body shakes" and monoamine neurotransmitters level in a model of kainic-induced seizures."3.77Effects of oxcarbazepine on monoamines content in hippocampus and head and body shakes and sleep patterns in kainic acid-treated rats. ( Alfaro-Rodríguez, A; Arch-Tirado, E; Ávila-Luna, A; Bueno-Nava, A; González-Piña, R; Uribe-Escamilla, R; Vargas-Sánchez, J, 2011)
"Systemic injection of pilocarpine has been shown to induce recurrent seizures and epileptic discharges demonstrated by EEG monitoring."3.76Lipoic acid effects on monoaminergic system after pilocarpine-induced seizures. ( Feng, D; Freitas, RM; Jordán, J, 2010)
" In the present study we performed parallel measurements of BDNF mRNA and protein expression in the frontal cortex and hippocampus of the rat after chronic treatment with electroconvulsive seizures (ECS), lithium, desipramine or escitalopram."3.72The effect of escitalopram, desipramine, electroconvulsive seizures and lithium on brain-derived neurotrophic factor mRNA and protein expression in the rat brain and the correlation to 5-HT and 5-HIAA levels. ( Jacobsen, JP; Mørk, A, 2004)
"The effects of valproate on CNS concentrations of gamma-aminobutyric acid (GABA), glulamate (GLU), glutamine (GLN); dopamine (DA), serotonin (5-HT), and metabolites were examined in tissue extracts of caudate nucleus of genetic substrains of Balb/c mice susceptible (EP) or resistant (ER) to audiogenic seizures."3.69Effects of valproate on amino acid and monoamine concentrations in striatum of audiogenic seizure-prone Balb/c mice. ( Alexiuk, NA; Vriend, JP, 1996)
" The effects of ECS on 5-HT, 5-HIAA, and HVA were compared to the effects of seizures induced by the convulsant agent flurothyl."3.68Neurochemical effects of electrically and chemically induced seizures: an in vivo microdialysis study in the rat hippocampus. ( Brown, EE; Damsma, G; Fibiger, HC; Nomikos, GG; Zis, AP, 1992)
"Concentrations of plasma amino acids and brain monoamines as well as pentylenetetrazol-induced seizures were monitored in CD-1 mice treated with aspartame in acute oral doses from 0 to 2500 mg/kg."3.67Aspartame fails to facilitate pentylenetetrazol-induced convulsions in CD-1 mice. ( Bettendorf, AF; Burger, RL; Dailey, JW; Jobe, PC; Lasley, SM; Mishra, PK, 1989)
"The intracerebral microdialysis technique has been used to monitor extracellular levels of noradrenaline, 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in the rat hippocampus in vivo in response to focal and generalized seizures induced by hippocampal kindling stimulation."3.67Noradrenaline and 5-hydroxytryptamine release in the hippocampus during seizures induced by hippocampal kindling stimulation: an in vivo microdialysis study. ( Bengzon, J; Kalén, P; Kokaia, M; Lindvall, O, 1989)
"The effects of fluoxetine [an inhibitor of 5-hydroxytryptamine (5-HT) reuptake] on electrically-induced spinal cord seizures were determined by monitoring alterations in the total duration of seizure, as well as the durations of tonic flexion and extension."3.66Effects of fluoxetine on electrically-induced spinal cord seizures in rats. ( Jobe, PC; Ray, TB; Woods, TW, 1980)
" The administration of 5-hydroxytryptophan with MK486 markedly depressed the incidence of seizures in the E1 mouse."3.66Brain monoamine levels and E1 mouse convulsions. ( Hiramatsu, M, 1981)
"The relationships between behavioral responses and levels of serotonin (5-HT) and 5-hydroxyindoleacetic acid (5-HIAA) in brain of mice were investigated after intravenous injection of fumitremorgin A (FTA)."3.66Biochemical investigation on the abnormal behaviors induced by fumitremorgin A, a tremorgenic mycotoxin to mice. ( Ozaki, N; Suzuki, S; Yamazaki, M, 1983)
"Chronic administration of the same dose of cocaine to rhesus monkeys for up to 6 months was associated with progressive alterations in pathological behavior and increased susceptibility to seizures."3.65Progressive effects of cocaine on behavior and central amine metabolism in rhesus monkeys: relationship to kindling and psychosis. ( Black, KE; Kopanda, RT; Post, RM, 1976)
"Six of them showed initial decrease of seizure frequency and severity and maintained improvement in some neurodevelopmental skills."1.72Monoamine neurotransmitters in early epileptic encephalopathies: New insights into pathophysiology and therapy. ( Aparicio, J; Artuch, R; Cortès-Saladelafont, E; Cuadras, D; Fons, C; García-Cazorla, À; Horvath, G; Juliá-Palacios, N; Molina-Anguita, C; Sigatulina Bondarenko, M, 2022)
" Rats that did not become hyperthermic when dosed with 15 mg/kg AMPH in a cold environment (10 degrees C) exhibited some hyperactivity and stereotypic behavior, but not overt convulsive behavior."1.31Seizure activity and hyperthermia potentiate the increases in dopamine and serotonin extracellular levels in the amygdala during exposure to d-amphetamine. ( Bowyer, JF; Tor-Agbidye, J; Yamamoto, B, 2001)
"In the seizure animals, neurotransmitter metabolites remained at low levels, as if the hypoxia had continued after the period of ischemia, inhibiting monoamine oxidase activity and, perhaps, neurotransmitter recapture."1.29Temporal profile of aminergic neurotransmitter release in striatal dialysates in rats with post-ischemic seizures. ( Allain, H; Bellissant, E; Bentué-Ferrer, D; Decombe, R, 1994)
"El mouse convulsions were inhibited by oral administration of citalopram for 2 weeks."1.29The anticonvulsant effect of citalopram on El mice, and the levels of tryptophan and tyrosine and their metabolites in the brain. ( Kabuto, H; Kurimoto, T; Mori, A; Takei, M; Yokoi, I, 1994)
"The data suggest that seizure-prone BALB/c mice have a deficiency in intracellular content of both excitatory and inhibitory amino acids."1.29Determination of amino acids and monoamine neurotransmitters in caudate nucleus of seizure-resistant and seizure-prone BALB/c mice. ( Alexiuk, NA; Green-Johnson, J; Ryan, E; Vriend, J, 1993)
"During tonic convulsions, the amplitude of the DOPAC oxidation peak significantly decreased to 75% of the peak height recorded prior to the injection of PTZ, and the minimum lasted for about 30 min; then the mean curve slowly recovered to the control level within 60 min."1.27Determination of neurotransmitter release into the caudate nucleus during convulsions induced by pentylenetetrazole using in vivo differential pulse voltammetry. ( Fujikawa, N; Mori, A; Shirasu, A; Yamamoto, M; Yokoi, I, 1986)
"Harmalan induced clonic convulsions which were antagonized by diazepam."1.27Pharmacology of harmalan (1-methyl-3,4-dihydro-beta-carboline). ( Brüning, G; Hill, R; Nick, M; Rommelspacher, H; Susilo, R, 1985)
" The controls were comprised of naive rats (G-VI) and naive rats dosed in the same manner as the dependent rats."1.26Participant of serotonin turnover rate in the brain on barbital withdrawal convulsion. ( Hiramori, T; Nakao, K; Tagashira, E; Urano, T; Yanaura, S, 1982)
"The pattern of maximal electroshock seizure was not affected by LC lesion, although the recovery time was slightly prolonged."1.26The role of the locus coeruleus in regulation of seizure susceptibility in rats. ( Oishi, R; Suenaga, N, 1982)
"It is postulated that the seizures and neurological deterioration of the patient were related to a deficiency in the synthesis of biogenic amine neurotransmitters."1.26Biogenic amine synthesis defect in dihydropteridine reductase deficiency. ( Butler, IJ; Koslow, SH, 1977)
"Taurine was effective in reducing the hypnotic effect of ethanol but did not antagonize the effect of ethanol on seizure susceptibility, body temperature, or brain 5-HIAA concentration."1.26Effect of taurine on some pharmacological properties of ethanol. ( Boggan, WO; Hopkins, DH; Medberry, C, 1978)

Research

Studies (74)

TimeframeStudies, this research(%)All Research%
pre-199052 (70.27)18.7374
1990's9 (12.16)18.2507
2000's6 (8.11)29.6817
2010's6 (8.11)24.3611
2020's1 (1.35)2.80

Authors

AuthorsStudies
Juliá-Palacios, N1
Molina-Anguita, C1
Sigatulina Bondarenko, M1
Cortès-Saladelafont, E1
Aparicio, J1
Cuadras, D1
Horvath, G1
Fons, C1
Artuch, R2
García-Cazorla, À1
Kuśmierska, K1
Szymańska, K1
Rokicki, D1
Kotulska, K1
Jóźwiak, S1
Sykut-Cegielska, J1
Mierzewska, H1
Szczepanik, E1
Pronicka, E1
Demkow, U1
Horvath, GA1
Demos, M1
Shyr, C1
Matthews, A1
Zhang, L1
Race, S1
Stockler-Ipsiroglu, S1
Van Allen, MI1
Mancarci, O1
Toker, L1
Pavlidis, P1
Ross, CJ1
Wasserman, WW1
Trump, N1
Heales, S1
Pope, S1
Cross, JH1
van Karnebeek, CD1
Guan, LP1
Liu, BY1
Quan, YC1
Yang, LY1
Zhen, XH1
Wang, SH1
Temudo, T1
Rios, M1
Prior, C1
Carrilho, I1
Santos, M1
Maciel, P1
Sequeiros, J1
Fonseca, M1
Monteiro, J1
Cabral, P1
Vieira, JP1
Ormazabal, A1
Freitas, RM1
Jordán, J1
Feng, D1
Alfaro-Rodríguez, A1
González-Piña, R1
Bueno-Nava, A1
Arch-Tirado, E1
Ávila-Luna, A1
Uribe-Escamilla, R1
Vargas-Sánchez, J1
Boissonnet, A1
Hévor, T1
Landemarre, L1
Cloix, JF1
Couvreur, G1
Demougeot, C1
Maugras, C1
Marie, C1
Beley, P1
Giroud, M1
SERRA, U1
SACCHETTI, G1
Jacobsen, JP1
Mørk, A1
Loke, WK1
Sim, MK1
Go, ML1
McNamara, R1
Kerans, A1
O'Neill, B1
Harkin, A1
Georgiev, VP1
Klousha, VE1
Petkov, VD1
Markovska, VL1
Svirskis, SV1
Mountsinietse, RK1
Anouans, ZE1
Jobe, PC2
Woods, TW1
Ray, TB1
Lebrecht, U1
Nowak, JZ1
Habel, A1
Yates, CM1
McQueen, JK1
Blackwood, D1
Elton, RA1
Hiramatsu, M2
Bobkova, NV1
Kalmykov, VL1
Katkov, IuA1
Tagashira, E1
Hiramori, T1
Urano, T1
Nakao, K1
Yanaura, S1
Munkenbeck, KE1
Schwark, WS1
Homeida, AM1
Cooke, RG1
Bakhit, C1
Shenoy, AK1
Swinyard, EA1
Gibb, JW1
Oishi, R1
Suenaga, N1
Mikhaĭlov, IB1
Gusel', VA1
Trottier, S1
Claustre, Y1
Caboche, J1
Dedek, J1
Chauvel, P1
Nassif, S1
Scatton, B1
Yamazaki, M1
Suzuki, S1
Ozaki, N1
Snape, MF1
Colado, MI1
Green, AR1
Bentué-Ferrer, D1
Bellissant, E1
Decombe, R1
Allain, H1
Kabuto, H2
Yokoi, I2
Takei, M1
Kurimoto, T1
Mori, A4
Vriend, J1
Alexiuk, NA2
Green-Johnson, J1
Ryan, E1
el-Etri, MM1
Ennis, M1
Jiang, M1
Shipley, MT1
Vriend, JP1
Tor-Agbidye, J1
Yamamoto, B1
Bowyer, JF1
Lewis, D1
Isaac, L1
Koslow, SH1
Butler, IJ1
Ohshimo, T1
Philo, R1
Reiter, RJ1
McGill, JR1
Fukuyama, Y1
Ochiai, Y1
Hayakawa, T1
Miyagawa, F1
Calderini, G1
Carlsson, A1
Nordström, CH1
Kobayashi, K1
Boggan, WO3
Meyer, JS1
Middaugh, LD1
Sparks, DL1
Medberry, C1
Hopkins, DH1
Post, RM1
Kopanda, RT1
Black, KE1
Blum, K1
Wallace, JE1
Schwertner, HA1
Meyer, E1
Morgan, WW1
Przegaliński, E1
Makarov, AIu1
Kiselev, VN1
Loboda, EB1
Zis, AP2
Nomikos, GG2
Brown, EE1
Damsma, G2
Fibiger, HC2
Nagatani, T1
Yamamoto, T1
Takao, K1
Hashimoto, S1
Kasahara, K1
Sugihara, T1
Ueki, S1
Pagliusi, SR1
Löscher, W1
Marescau, B1
Yamamoto, M1
Fujikawa, N1
Shirasu, A1
Hara, S1
Satoh, T1
Kitagawa, H1
Suñol, C1
Tusell, JM1
Gelpí, E1
Rodríguez-Farré, E1
Dailey, JW1
Lasley, SM1
Mishra, PK1
Bettendorf, AF1
Burger, RL1
Kokaia, M1
Kalén, P1
Bengzon, J1
Lindvall, O1
Rommelspacher, H1
Brüning, G1
Susilo, R1
Nick, M1
Hill, R1
Paulson, GW2
Nance, W1
Son, C1
Son, CD1
Nance, WE1
Talarmain, Y1
Valzelli, L1
Lehmann, A1
Peters, DA2
Hrdina, PD2
Singhal, RL2
Ling, GM1
Diaz, PM1
Kellogg, C2
LaMantia, J1
Jacobson, J1
Tabakoff, B1
Stern, WC1
Forbes, WB1
Resnick, O1
Morgane, PJ1
Colasanti, BK1
Craig, CR1
Kilian, M1
Frey, HH1
Vogel, JR1
Haubrich, DR1
Okada, F1
Feldstein, A1
Sidel, CM1
Aschkenasy-Lelu, P1
Spach, C1

Reviews

1 review available for hydroxyindoleacetic acid and Seizures

ArticleYear
Brain monoamines in seizure mechanism (review).
    Folia psychiatrica et neurologica japonica, 1977, Volume: 31, Issue:3

    Topics: Animals; Brain; Carbonic Anhydrase Inhibitors; Catecholamines; Child; Dextroamphetamine; Dopamine; E

1977

Trials

2 trials available for hydroxyindoleacetic acid and Seizures

ArticleYear
Evaluation of CSF neurotransmitters and folate in 25 patients with Rett disorder and effects of treatment.
    Brain & development, 2009, Volume: 31, Issue:1

    Topics: Administration, Oral; Child; Child, Preschool; DNA Mutational Analysis; Female; Fluoxetine; Folic Ac

2009
5-Hydroxyindolacetic acid and homovanillic acid are not involved in the cerebrospinal fluid after a seizure in patients with Delirium Tremens.
    Neurological research, 2002, Volume: 24, Issue:6

    Topics: Adult; Aged; Alcohol Withdrawal Delirium; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male;

2002

Other Studies

71 other studies available for hydroxyindoleacetic acid and Seizures

ArticleYear
Monoamine neurotransmitters in early epileptic encephalopathies: New insights into pathophysiology and therapy.
    Developmental medicine and child neurology, 2022, Volume: 64, Issue:7

    Topics: Child, Preschool; Electroencephalography; Epilepsies, Myoclonic; Epilepsy; Female; Humans; Hydroxyin

2022
Age and Gender-Related Changes in Biogenic Amine Metabolites in Cerebrospinal Fluid in Children.
    Advances in experimental medicine and biology, 2016, Volume: 878

    Topics: Adolescent; Age Factors; Case-Control Studies; Child; Child, Preschool; Dopamine; Female; Homovanill

2016
Secondary neurotransmitter deficiencies in epilepsy caused by voltage-gated sodium channelopathies: A potential treatment target?
    Molecular genetics and metabolism, 2016, Volume: 117, Issue:1

    Topics: Autistic Disorder; Channelopathies; Child; Drug Resistant Epilepsy; Epilepsy; Exome; Female; Homovan

2016
Synthesis and Evaluation of Phenyliminoindolin-Containing Phenylacetamide Derivatives with the Antidepressant and Anticonvulsant Effects.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2016, Volume: 12, Issue:8

    Topics: Acetanilides; Animals; Anticonvulsants; Antidepressive Agents; Dopamine; Electroshock; Fluoxetine; H

2016
Lipoic acid effects on monoaminergic system after pilocarpine-induced seizures.
    Neuroscience letters, 2010, Jun-25, Volume: 477, Issue:3

    Topics: Animals; Antioxidants; Biogenic Monoamines; Dopamine; Hippocampus; Hydroxyindoleacetic Acid; Male; N

2010
Effects of oxcarbazepine on monoamines content in hippocampus and head and body shakes and sleep patterns in kainic acid-treated rats.
    Metabolic brain disease, 2011, Volume: 26, Issue:3

    Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Dopamine; Hippocampus; Homovanillic

2011
Monoamines and glycogen levels in cerebral cortices of fast and slow methionine sulfoximine-inbred mice.
    Epilepsy research, 2013, Volume: 104, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Brain; Disease Models, Animal; Glycoge

2013
[Urinary elimination of 5-hydroxyindolacetic acid in rabbits after cardiazol convulsions].
    Il Farmaco; edizione scientifica, 1961, Volume: 16

    Topics: Animals; Body Fluids; Hydroxyindoleacetic Acid; Indoleacetic Acids; Pentylenetetrazole; Rabbits; Sei

1961
The effect of escitalopram, desipramine, electroconvulsive seizures and lithium on brain-derived neurotrophic factor mRNA and protein expression in the rat brain and the correlation to 5-HT and 5-HIAA levels.
    Brain research, 2004, Oct-22, Volume: 1024, Issue:1-2

    Topics: Animals; Brain; Brain-Derived Neurotrophic Factor; Citalopram; Desipramine; Electroshock; Gene Expre

2004
Novel neuroprotective effects with O-benzyl derivative of pralidoxime in soman-intoxicated rodents.
    European journal of pharmacology, 2005, Oct-03, Volume: 521, Issue:1-3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Analysis of Variance; Animals; Anticonvulsants; Atrop

2005
Caffeine promotes hyperthermia and serotonergic loss following co-administration of the substituted amphetamines, MDMA ("Ecstasy") and MDA ("Love").
    Neuropharmacology, 2006, Volume: 50, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Area Under Curve; Behavior, Animal; Body Temperature; Brain

2006
Central effects of angiotensin II, its fragment and analogues.
    Acta physiologica et pharmacologica Bulgarica, 1984, Volume: 10, Issue:4

    Topics: Angiotensin II; Animals; Apomorphine; Behavior, Animal; Brain; Catalepsy; Catecholamines; Haloperido

1984
Effects of fluoxetine on electrically-induced spinal cord seizures in rats.
    Research communications in chemical pathology and pharmacology, 1980, Volume: 30, Issue:1

    Topics: Animals; Electric Stimulation; Female; Fluoxetine; Hydroxyindoleacetic Acid; Propylamines; Rats; Sei

1980
Effect of single and repeated electroconvulsive shock on serotonergic system in rat brain--I. Metabolic studies.
    Neuropharmacology, 1980, Volume: 19, Issue:11

    Topics: Animals; Brain; Electroshock; Hydroxyindoleacetic Acid; Hypothalamus; Male; Probenecid; Rats; Seizur

1980
Homovanillic acid and 5-hydroxyindoleacetic acid in lumbar cerebrospinal fluid in children with afebrile and febrile convulsions.
    Neurology, 1981, Volume: 31, Issue:4

    Topics: Child; Child, Preschool; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Lumbos

1981
Brain monoamine levels and E1 mouse convulsions.
    Folia psychiatrica et neurologica japonica, 1981, Volume: 35, Issue:3

    Topics: 5-Hydroxytryptophan; alpha-Methyltyrosine; Animals; Brain; Dioxoles; Dopamine; Evoked Potentials; Fu

1981
[Levels of biogenic amines in the brains of rats with different susceptibilities to audiogenic seizures].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1981, Volume: 67, Issue:12

    Topics: Acoustic Stimulation; Animals; Biogenic Amines; Brain Chemistry; Disease Susceptibility; Hydroxyindo

1981
Participant of serotonin turnover rate in the brain on barbital withdrawal convulsion.
    Japanese journal of pharmacology, 1982, Volume: 32, Issue:1

    Topics: Animals; Barbital; Barbiturates; Brain; Chlorpromazine; Humans; Hydroxyindoleacetic Acid; Male; Nitr

1982
Serotonergic mechanisms in amygdaloid-kindled seizures in the rat.
    Experimental neurology, 1982, Volume: 76, Issue:2

    Topics: 5-Hydroxytryptophan; Amygdala; Animals; Brain; Female; Fenclonine; Hydroxyindoleacetic Acid; Kindlin

1982
Pharmacological aspects of metaldehyde poisoning in mice.
    Journal of veterinary pharmacology and therapeutics, 1982, Volume: 5, Issue:1

    Topics: Acetaldehyde; Animals; Brain; Clonidine; Diazepam; Female; Hydroxyindoleacetic Acid; Male; Mice; Mic

1982
Altered neurochemical parameters in the brains of mice (Frings) susceptible to audiogenic seizures.
    Brain research, 1982, Jul-22, Volume: 244, Issue:1

    Topics: Acoustic Stimulation; Animals; Anticonvulsants; Brain; Dopamine; Electroshock; Female; Hydroxyindole

1982
The role of the locus coeruleus in regulation of seizure susceptibility in rats.
    Japanese journal of pharmacology, 1982, Volume: 32, Issue:6

    Topics: Animals; Brain Chemistry; Electroshock; Hydroxyindoleacetic Acid; Locus Coeruleus; Male; Norepinephr

1982
[Pharmaco-dynamic mechanisms for reducing the activity of an epileptogenic focus with allopurinol].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1983, Volume: 83, Issue:6

    Topics: Allopurinol; Animals; Hippocampus; Hydroxyindoleacetic Acid; Male; Penicillins; Rats; Seizures; Sero

1983
Alterations of noradrenaline and serotonin uptake and metabolism in chronic cobalt-induced epilepsy in the rat.
    Brain research, 1983, Aug-08, Volume: 272, Issue:2

    Topics: Animals; Cerebral Cortex; Cobalt; Hydroxyindoleacetic Acid; Kinetics; Male; Methoxyhydroxyphenylglyc

1983
Biochemical investigation on the abnormal behaviors induced by fumitremorgin A, a tremorgenic mycotoxin to mice.
    Journal of pharmacobio-dynamics, 1983, Volume: 6, Issue:10

    Topics: Animals; Behavior, Animal; Brain; Brain Chemistry; Hydroxyindoleacetic Acid; Indenes; Male; Mice; Se

1983
Chlormethiazole and dizocilpine block the behavioural, but not the neurotoxic effects of 5,7-dihydroxytryptamine in mice.
    Pharmacology & toxicology, 1994, Volume: 74, Issue:1

    Topics: 5,7-Dihydroxytryptamine; Animals; Behavior, Animal; Brain; Chlormethiazole; Dizocilpine Maleate; Hyd

1994
Temporal profile of aminergic neurotransmitter release in striatal dialysates in rats with post-ischemic seizures.
    Experimental brain research, 1994, Volume: 97, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Dopamine; Homovanillic Acid; Hydroxyin

1994
The anticonvulsant effect of citalopram on El mice, and the levels of tryptophan and tyrosine and their metabolites in the brain.
    Neurochemical research, 1994, Volume: 19, Issue:4

    Topics: Animals; Anticonvulsants; Brain; Cerebral Cortex; Citalopram; Corpus Striatum; Hippocampus; Homovani

1994
Determination of amino acids and monoamine neurotransmitters in caudate nucleus of seizure-resistant and seizure-prone BALB/c mice.
    Journal of neurochemistry, 1993, Volume: 60, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids; Animals; Biogenic Monoamines; Caudate Nucleus; Dopamine

1993
Pilocarpine-induced convulsions in rats: evidence for muscarinic receptor-mediated activation of locus coeruleus and norepinephrine release in cholinolytic seizure development.
    Experimental neurology, 1993, Volume: 121, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Locu

1993
Effects of valproate on amino acid and monoamine concentrations in striatum of audiogenic seizure-prone Balb/c mice.
    Molecular and chemical neuropathology, 1996, Volume: 27, Issue:3

    Topics: Acoustic Stimulation; Amino Acids; Animals; Anticonvulsants; Biogenic Monoamines; Corpus Striatum; D

1996
Seizure activity and hyperthermia potentiate the increases in dopamine and serotonin extracellular levels in the amygdala during exposure to d-amphetamine.
    Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 60, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Amygdala; Animals; Behavior, Animal; Chromatography, Hi

2001
Effects of antihistaminic drugs on feline brain monoamine metabolism.
    Biochemical pharmacology, 1977, Jan-15, Volume: 26, Issue:2

    Topics: Animals; Body Temperature; Cats; Diphenhydramine; Dopamine; Electroencephalography; Histamine H1 Ant

1977
Biogenic amine synthesis defect in dihydropteridine reductase deficiency.
    Science (New York, N.Y.), 1977, Nov-04, Volume: 198, Issue:4316

    Topics: 5-Hydroxytryptophan; Biogenic Amines; Carbidopa; Dopamine; Homovanillic Acid; Humans; Hydroxyindolea

1977
[Relationship of seizure susceptibility and generalized convulsion to brain monoamine concentration in the kindled cat brain (author's transl)].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1978, Volume: 80, Issue:9

    Topics: Adolescent; Animals; Biogenic Amines; Brain Chemistry; Electric Stimulation; Homovanillic Acid; Huma

1978
Changes in brain dopamine, norepinephrine and serotonin associated with convulsions induced by pinealectomy in the gerbil.
    Journal of neural transmission, 1979, Volume: 46, Issue:3

    Topics: Animals; Body Temperature; Dopamine; Gerbillinae; Hydroxyindoleacetic Acid; Male; Norepinephrine; Pi

1979
Overnight sleep EEG and cerebrospinal fluid monoamines in seizures induced by movement.
    Neuropadiatrie, 1979, Volume: 10, Issue:2

    Topics: Child; Electroencephalography; Haloperidol; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Lev

1979
Monoamine metabolism during bicuculline-induced epileptic seizures in the rat.
    Brain research, 1978, Nov-24, Volume: 157, Issue:2

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Bicuculline; Brain; Catecholamines; Cerebellum; Corpus St

1978
Ethanol, calcium, and naloxone in mice.
    Alcoholism, clinical and experimental research, 1979, Volume: 3, Issue:2

    Topics: Animals; Brain; Calcium; Corticosterone; Dose-Response Relationship, Drug; Drug Interactions; Ethano

1979
Effect of taurine on some pharmacological properties of ethanol.
    Pharmacology, biochemistry, and behavior, 1978, Volume: 9, Issue:4

    Topics: Animals; Body Temperature; Brain Chemistry; Drug Interactions; Ethanol; Hydroxyindoleacetic Acid; Ma

1978
Progressive effects of cocaine on behavior and central amine metabolism in rhesus monkeys: relationship to kindling and psychosis.
    Biological psychiatry, 1976, Volume: 11, Issue:4

    Topics: Animals; Behavior, Animal; Catalepsy; Cocaine; Female; Haplorhini; Homovanillic Acid; Humans; Hydrox

1976
Central supersensitivity to norepinephrine and amphetamine following brain chemical sympathectomy by 6-hydroxydopamine.
    Life sciences, 1977, May-15, Volume: 20, Issue:10

    Topics: Animals; Brain; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Hydro

1977
Convulsive thresholds and the activity of anticonvulsants in electroseizure test. The role of serotoninergic system.
    Polish journal of pharmacology and pharmacy, 1976, Volume: 28, Issue:2

    Topics: Animals; Anticonvulsants; Brain Chemistry; Dopamine; Electroshock; Hydroxyindoleacetic Acid; Male; M

1976
[The role of serotonin in the pathogenesis of epilepsy].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1975, Volume: 75, Issue:3

    Topics: Adolescent; Adult; Arachnoiditis; Epilepsy; Female; Humans; Hydroxyindoleacetic Acid; Male; Seizures

1975
Neurochemical effects of electrically and chemically induced seizures: an in vivo microdialysis study in the rat hippocampus.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1992, Volume: 7, Issue:3

    Topics: Acetylcholine; Analysis of Variance; Animals; Dialysis; Electroshock; Flurothyl; Hippocampus; Homova

1992
In vivo neurochemical effects of electroconvulsive shock studied by microdialysis in the rat striatum.
    Psychopharmacology, 1991, Volume: 103, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Animals; Brain Chemistry; Choline; Convulsants; Corpu

1991
Pharmacological profile of a potential anxiolytic: AP159, a new benzothieno-pyridine derivative.
    Psychopharmacology, 1991, Volume: 104, Issue:4

    Topics: Aggression; Animals; Anti-Anxiety Agents; Avoidance Learning; Conflict, Psychological; Drinking Beha

1991
Development of tolerance to the wet-dog shake behaviour but not the increase in seizure threshold induced by L-5-hydroxytryptophan during continued treatment in rats.
    Psychopharmacology, 1985, Volume: 86, Issue:1-2

    Topics: 5-Hydroxytryptophan; Animals; Body Temperature; Body Weight; Brain Chemistry; Carbidopa; Drug Intera

1985
Effects of emotional stress on E1-mouse convulsions, and their biochemical background.
    Neurochemical research, 1986, Volume: 11, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Dopamine; Homovanillic Acid; Hydroxyindole

1986
Determination of neurotransmitter release into the caudate nucleus during convulsions induced by pentylenetetrazole using in vivo differential pulse voltammetry.
    Brain research, 1986, Oct-22, Volume: 385, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Dopamine; Electroencephalography; Hydroxyi

1986
Suppression of pentylenetetrazol-induced seizures by hydralazine associated with 5-hydroxytryptaminergic system in rat brain.
    Japanese journal of pharmacology, 1987, Volume: 43, Issue:4

    Topics: alpha-Methyltyrosine; Animals; Brain; Fenclonine; Hydralazine; Hydroxyindoleacetic Acid; Male; Methy

1987
Regional concentrations of GABA, serotonin and noradrenaline in brain at onset of seizures induced by lindane (gamma-hexachlorocyclohexane).
    Neuropharmacology, 1988, Volume: 27, Issue:7

    Topics: Animals; Brain Chemistry; Chromatography, Gas; Chromatography, High Pressure Liquid; gamma-Aminobuty

1988
Aspartame fails to facilitate pentylenetetrazol-induced convulsions in CD-1 mice.
    Toxicology and applied pharmacology, 1989, Volume: 98, Issue:3

    Topics: Amino Acids; Animals; Aspartame; Brain Chemistry; Dipeptides; Hydroxyindoleacetic Acid; Male; Mice;

1989
Noradrenaline and 5-hydroxytryptamine release in the hippocampus during seizures induced by hippocampal kindling stimulation: an in vivo microdialysis study.
    Neuroscience, 1989, Volume: 32, Issue:3

    Topics: Animals; Desipramine; Hippocampus; Hydroxydopamines; Hydroxyindoleacetic Acid; Kindling, Neurologic;

1989
Pharmacology of harmalan (1-methyl-3,4-dihydro-beta-carboline).
    European journal of pharmacology, 1985, Mar-12, Volume: 109, Issue:3

    Topics: Animals; Behavior, Animal; Binding Sites; Carbolines; Cerebral Cortex; Convulsants; Female; Hydroxyi

1985
Neurologic aspects of typical and atypical Down's syndrome.
    Neurology, 1968, Volume: 18, Issue:3

    Topics: Child; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Down Syndrome; Electroencepha

1968
Neurologic aspects of typical and atypical Down's syndrome.
    Diseases of the nervous system, 1969, Volume: 30, Issue:9

    Topics: Cataract; Chromosome Aberrations; Down Syndrome; Gait; Humans; Hydroxyindoleacetic Acid; Intelligenc

1969
[Turnover of serotonin. Its relations with audiogenic seizures in mice].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1970, Volume: 164, Issue:1

    Topics: Animals; Brain; Hydroxyindoleacetic Acid; Mice; Seizures; Serotonin

1970
The role of brain serotonin in DDT-induced hyperpyrexia.
    Journal of neurochemistry, 1972, Volume: 19, Issue:4

    Topics: Animals; Brain; Brain Stem; DDT; Fenclonine; Fever; Fluorine; Hydroxyindoleacetic Acid; Male; Pargyl

1972
Interaction of pentylenetetrazol and trimethadione on the metabolism of serotonin in brain and its relation to the anticonvulsant action of trimethadione.
    Neuropharmacology, 1974, Volume: 13, Issue:7

    Topics: 5-Hydroxytryptophan; Animals; Anticonvulsants; Brain; Brain Chemistry; Dose-Response Relationship, D

1974
Analysis of seizures induced by a catechol-derivative.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 285, Issue:3

    Topics: Acoustic Stimulation; Aging; Animals; Biogenic Amines; Brain Chemistry; Catechols; Dose-Response Rel

1974
Effects of ethanol on serotonin metabolism in brain.
    Journal of neurochemistry, 1974, Volume: 22, Issue:5

    Topics: Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Animals; Behavior, Animal; Brain; Ethanol; Hydrox

1974
Seizure susceptibility and brain amine levels following protein malnutrition during development in the rat.
    Brain research, 1974, Oct-25, Volume: 79, Issue:3

    Topics: Animals; Animals, Newborn; Brain; Brain Chemistry; Dietary Proteins; Electric Stimulation; Female; H

1974
Brain concentrations and synthesis rates of biogenic amines during chronic cobalt experimental epilepsy in the rat.
    Neuropharmacology, 1973, Volume: 12, Issue:3

    Topics: Animals; Biogenic Amines; Brain; Cobalt; Dopamine; Hydroxyindoleacetic Acid; Male; Norepinephrine; R

1973
Central monoamines and convulsine thresholds in mice and rats.
    Neuropharmacology, 1973, Volume: 12, Issue:7

    Topics: Amphetamine; Animals; Biogenic Amines; Brain; Dopamine; Electroshock; Female; Hydroxyindoleacetic Ac

1973
Chronic administration of electroconvulsive shock effects on mouse-killing activity and brain monoamines in rats.
    Physiology & behavior, 1973, Volume: 11, Issue:5

    Topics: Aggression; Animals; Body Weight; Brain Chemistry; Disease Models, Animal; Dopamine; Electroshock; F

1973
[Regional changes of serotonin, 5-hydroxyindoleacetic acid and norepinephrine in the rat brain in the process of convulsive seizures (author's transl)].
    Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1973, Volume: 75, Issue:7

    Topics: Animals; Brain; Hydroxyindoleacetic Acid; Male; Norepinephrine; Rats; Seizures; Serotonin

1973
Role of noradrenaline, 5-hydroxytryptamine and acetylcholine in the hypothermic and convulsive effects of alpha-chlordane in rats.
    European journal of pharmacology, 1974, Volume: 26, Issue:2

    Topics: Acetylcholine; Acetylcholinesterase; Animals; Body Temperature; Brain; Brain Chemistry; Brain Stem;

1974
Serotonin metabolism in the brains of mice sensitive or resistant to audiogenic seizures.
    Journal of neurobiology, 1971, Volume: 2, Issue:3

    Topics: Animals; Brain; Brain Chemistry; Carboxy-Lyases; Female; Hydroxyindoleacetic Acid; Mice; Mice, Inbre

1971
Phenelzine-induced convulsions and alterations in the conversion of 5-HTP-14C to serotonin-14C in vivo.
    Biochemical pharmacology, 1966, Volume: 15, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Brain; Carboxy-Lyases; Hydroxyindoleacetic Acid; In Vitro Techniques;

1966
[Relation between peculiarities of behavior and the metabolism of serotonin in a strain of Wistar rats showing the "hairless" mutation].
    Archives des sciences physiologiques, 1971, Volume: 25, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Female; Genetics, Behavioral; Hair; Hybridiza

1971