thiamine has been researched along with Seizures in 41 studies
thiamine(1+) : A primary alcohol that is 1,3-thiazol-3-ium substituted by (4-amino-2-methylpyrimidin-5-yl)methyl, methyl and 2-hydroxyethyl groups at positions 3, 4 and 5, respectively.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The study looked at how the thiamine supplement impacted pentylenetetrazole (PTZ)-induced seizures in rats and pentylenetetrazole-induced neurotoxicity in the SH-SY5Y cell line." | 8.02 | The modulator action of thiamine against pentylenetetrazole-induced seizures, apoptosis, nitric oxide, and oxidative stress in rats and SH-SY5Y neuronal cell line. ( Ergul, M; Taskiran, AS, 2021) |
| "Objectives The objective of this study was to determine disease progression, association between neurological signs and magnetic resonance imaging (MRI) findings, and long-term outcome in feline thiamine deficiency associated with defective dry food." | 7.85 | Outbreak of thiamine deficiency in cats associated with the feeding of defective dry food. ( Chang, YP; Chiu, PY; Lin, CT; Liu, CH; Liu, IH, 2017) |
| " Both cats were diagnosed with thiamine deficiency." | 7.79 | Clinical signs, MRI features, and outcomes of two cats with thiamine deficiency secondary to diet change. ( Kang, MH; Moon, SJ; Park, HM, 2013) |
| "Thiamine (vitamin B(1)) is an essential component of a number of metabolic pathways and thiamine deficiency results in a progressive encephalopathy in both humans and animals." | 7.76 | Thiamine deficiency in a cat: resolution of MRI abnormalities following thiamine supplementation. ( Cherubini, GB; Jakovljevic, S; Palus, V; Penderis, J, 2010) |
| "The current study measured extracellular fluid (ECF) levels of excitatory amino acids before and during the onset of thiamine deficiency-induced pathologic lesions." | 7.68 | Extracellular glutamate is increased in thalamus during thiamine deficiency-induced lesions and is blocked by MK-801. ( Langlais, PJ; Zhang, SX, 1993) |
| "Evidence suggests that improving brain inflammation can inhibit the epileptogenesis process and help the emergence of new drugs for the treatment of epilepsy." | 5.72 | Thiamine alleviates cognitive impairment and epileptogenesis by relieving brain inflammation in PTZ-induced kindling rat model. ( Akkaya, R; Filiz, AK; Karabulut, S, 2022) |
| "Acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) is the most prevalent encephalopathy in Japanese children." | 5.51 | Early administration of vitamins B1 and B6 and l-carnitine prevents a second attack of acute encephalopathy with biphasic seizures and late reduced diffusion: A case control study. ( Fukui, KO; Ishiguro, A; Kashii, H; Kubota, M; Terashima, H, 2019) |
| " We reviewed 13 patients (median age, 27 years; 5 men) with clear histories of thiamine deficiency and symptoms of typical WE." | 4.95 | Epileptic seizures in nonalcoholic Wernicke's encephalopathy: a case report and literature review. ( Chen, H; Chen, X; Hong, H; Li, X; Shang, W; Tang, S, 2017) |
| "Wernicke's encephalopathy (WE) is a serious neurologic condition resulting from thiamine deficiency." | 4.93 | Nonalcoholic Wernicke's encephalopathy. ( Clift, F; Rogers, P; Welsh, A, 2016) |
| " The study looked at how the thiamine supplement impacted pentylenetetrazole (PTZ)-induced seizures in rats and pentylenetetrazole-induced neurotoxicity in the SH-SY5Y cell line." | 4.02 | The modulator action of thiamine against pentylenetetrazole-induced seizures, apoptosis, nitric oxide, and oxidative stress in rats and SH-SY5Y neuronal cell line. ( Ergul, M; Taskiran, AS, 2021) |
| " The present study was designed to investigate the effect of acute and chronic administration of thiamine alone and in combination with sub-effective dose of diazepam on pentylenetetrazole (PTZ)-induced tonic-clonic seizures in mice." | 3.91 | Anticonvulsant effects of thiamine on pentylenetetrazole-induced seizure in mice. ( Abed, A; Alinejad, M; Banafshe, HR; Heydari, A; Mesdaghinia, A, 2019) |
| "Objectives The objective of this study was to determine disease progression, association between neurological signs and magnetic resonance imaging (MRI) findings, and long-term outcome in feline thiamine deficiency associated with defective dry food." | 3.85 | Outbreak of thiamine deficiency in cats associated with the feeding of defective dry food. ( Chang, YP; Chiu, PY; Lin, CT; Liu, CH; Liu, IH, 2017) |
| " Both cats were diagnosed with thiamine deficiency." | 3.79 | Clinical signs, MRI features, and outcomes of two cats with thiamine deficiency secondary to diet change. ( Kang, MH; Moon, SJ; Park, HM, 2013) |
| "A Medline search using the terms 'thiamine deficiency' and 'formula' or 'feeding' without year limit identified relevant published data on that event." | 3.78 | Thiamine-deficient infant formula: what happened and what have we learned? ( Shamir, R, 2012) |
| "Thiamine (vitamin B(1)) is an essential component of a number of metabolic pathways and thiamine deficiency results in a progressive encephalopathy in both humans and animals." | 3.76 | Thiamine deficiency in a cat: resolution of MRI abnormalities following thiamine supplementation. ( Cherubini, GB; Jakovljevic, S; Palus, V; Penderis, J, 2010) |
| "The current study measured extracellular fluid (ECF) levels of excitatory amino acids before and during the onset of thiamine deficiency-induced pathologic lesions." | 3.68 | Extracellular glutamate is increased in thalamus during thiamine deficiency-induced lesions and is blocked by MK-801. ( Langlais, PJ; Zhang, SX, 1993) |
| "Evidence suggests that improving brain inflammation can inhibit the epileptogenesis process and help the emergence of new drugs for the treatment of epilepsy." | 1.72 | Thiamine alleviates cognitive impairment and epileptogenesis by relieving brain inflammation in PTZ-induced kindling rat model. ( Akkaya, R; Filiz, AK; Karabulut, S, 2022) |
| "The diagnosis of Wernicke encephalopathy in our patient is based on increased thiamine requirement due to pregnancy, nystagmus, low transketolase level, and reversal of symptoms after thiamine replacement." | 1.72 | Wernicke encephalopathy with epileptic seizures during pregnancy. ( Beckmann, Y; Mengi, T, 2022) |
| "On the 15th day, the seizure was induced (except the control group) by intraperitoneal injection of PTZ." | 1.62 | Anti-convulsive Effect of Thiamine and Melatonin Combination in Mice: Involvement of Oxidative Stress. ( Dehdashtian, E; Fatemi, I; Hemati, K; Hosseinzadeh, A; Karimi, MY; Mehrzadi, S, 2021) |
| "Acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) is the most prevalent encephalopathy in Japanese children." | 1.51 | Early administration of vitamins B1 and B6 and l-carnitine prevents a second attack of acute encephalopathy with biphasic seizures and late reduced diffusion: A case control study. ( Fukui, KO; Ishiguro, A; Kashii, H; Kubota, M; Terashima, H, 2019) |
| "Atrophy and gliosis in the affected regions were observed in patients with chronic disease." | 1.39 | Biotin-responsive basal ganglia disease revisited: clinical, radiologic, and genetic findings. ( Al-Adwani, N; Al-Hashem, A; Al-Shafi, S; Al-Shahwan, S; Al-Zawahmah, M; Azmat, Z; Biary, N; Khan, S; Tabarki, B; Zuccoli, G, 2013) |
| "Clinically, we most often associate Wernicke's encephalopathy (WE) with an alcohol abusing population." | 1.33 | Wernicke's encephalopathy in a patient with schizophrenia. ( Harrison, RA; Hunter, AJ; Vu, T, 2006) |
| "Management of seizures requires prompt medical attention to prevent morbidity and mortality and to clarify the etiology of the event so that proper long-range therapy can be planned." | 1.27 | Convulsions. ( Bean, SC, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (51.22) | 18.7374 |
| 1990's | 2 (4.88) | 18.2507 |
| 2000's | 2 (4.88) | 29.6817 |
| 2010's | 11 (26.83) | 24.3611 |
| 2020's | 5 (12.20) | 2.80 |
| Authors | Studies |
|---|---|
| Karabulut, S | 1 |
| Filiz, AK | 1 |
| Akkaya, R | 1 |
| Mengi, T | 1 |
| Beckmann, Y | 1 |
| Zambon, AA | 1 |
| Ghezzi, D | 1 |
| Baldoli, C | 1 |
| Cutillo, G | 1 |
| Fontana, K | 1 |
| Sofia, V | 1 |
| Patricelli, MG | 1 |
| Nasca, A | 1 |
| Vinci, S | 1 |
| Spiga, I | 1 |
| Lamantea, E | 1 |
| Fanelli, GF | 1 |
| Sora, MGN | 1 |
| Rovelli, R | 1 |
| Poloniato, A | 1 |
| Carrera, P | 1 |
| Filippi, M | 1 |
| Barera, G | 1 |
| Taskiran, AS | 1 |
| Ergul, M | 1 |
| Dehdashtian, E | 1 |
| Hosseinzadeh, A | 1 |
| Hemati, K | 1 |
| Karimi, MY | 1 |
| Fatemi, I | 1 |
| Mehrzadi, S | 1 |
| Mesdaghinia, A | 1 |
| Alinejad, M | 1 |
| Abed, A | 1 |
| Heydari, A | 1 |
| Banafshe, HR | 1 |
| Shang, W | 1 |
| Chen, X | 1 |
| Li, X | 1 |
| Chen, H | 1 |
| Tang, S | 1 |
| Hong, H | 1 |
| Eichler, FS | 1 |
| Swoboda, KJ | 1 |
| Hunt, AL | 1 |
| Cestari, DM | 1 |
| Rapalino, O | 1 |
| Fukui, KO | 1 |
| Kubota, M | 1 |
| Terashima, H | 1 |
| Ishiguro, A | 1 |
| Kashii, H | 1 |
| Moon, SJ | 1 |
| Kang, MH | 1 |
| Park, HM | 1 |
| Welsh, A | 1 |
| Rogers, P | 1 |
| Clift, F | 1 |
| Chang, YP | 1 |
| Chiu, PY | 1 |
| Lin, CT | 1 |
| Liu, IH | 1 |
| Liu, CH | 1 |
| Palus, V | 1 |
| Penderis, J | 1 |
| Jakovljevic, S | 1 |
| Cherubini, GB | 1 |
| Shamir, R | 1 |
| Gregory, J | 1 |
| Philbrick, K | 1 |
| Chopra, A | 1 |
| Tabarki, B | 1 |
| Al-Shafi, S | 1 |
| Al-Shahwan, S | 1 |
| Azmat, Z | 1 |
| Al-Hashem, A | 1 |
| Al-Adwani, N | 1 |
| Biary, N | 1 |
| Al-Zawahmah, M | 1 |
| Khan, S | 1 |
| Zuccoli, G | 1 |
| WARREN, KS | 1 |
| SCHENKER, S | 1 |
| YAMAMOTO, I | 1 |
| OSTOVSKII, IuM | 1 |
| NEPOCHELOVICH, NS | 1 |
| ISRAELS, S | 1 |
| HAWORTH, JC | 1 |
| GOURLEY, B | 1 |
| FORD, JD | 1 |
| RAO, RR | 1 |
| SUBRAHMANYAM, I | 1 |
| HARA, S | 1 |
| TAMURA, T | 1 |
| YAKAZU, K | 1 |
| HORIBE, M | 1 |
| SATO, S | 1 |
| KIKUTA, K | 1 |
| SEEWALD, LO | 1 |
| Harrison, RA | 1 |
| Vu, T | 1 |
| Hunter, AJ | 1 |
| Lewis, DC | 1 |
| Femino, J | 1 |
| Holloway, HC | 1 |
| Hales, RE | 1 |
| Watanabe, HK | 1 |
| Irle, E | 1 |
| Markowitsch, HJ | 1 |
| Langlais, PJ | 1 |
| Zhang, SX | 1 |
| Cheong, JH | 1 |
| Seo, DO | 1 |
| Ryu, JR | 1 |
| Shin, CY | 1 |
| Kim, YT | 1 |
| Kim, HC | 1 |
| Kim, WK | 1 |
| Ko, KH | 1 |
| Delis, D | 1 |
| Michelakakis, H | 1 |
| Katsarou, E | 1 |
| Bartsocas, CS | 1 |
| Moran, JR | 1 |
| Greene, HL | 1 |
| Robertson, CC | 1 |
| Sellers, EM | 1 |
| Itokawa, Y | 1 |
| Bean, SC | 1 |
| Kaim, SC | 3 |
| Rothstein, E | 1 |
| Klett, CJ | 2 |
| Rothfeld, B | 1 |
| Hollister, LE | 1 |
| Caffey, EM | 1 |
| Bitter, RA | 1 |
| Gubler, CJ | 2 |
| Heninger, RW | 1 |
| Lister, EE | 1 |
| Fisher, LJ | 1 |
| Cheney, DL | 1 |
| Jaussi, AW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phenobarbital Versus Ativan for Refractory Alcohol Withdrawal Treatment in the Intensive Care Unit[NCT04156464] | Phase 4 | 142 participants (Anticipated) | Interventional | 2020-07-06 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for thiamine and Seizures
| Article | Year |
|---|---|
Epileptic seizures in nonalcoholic Wernicke's encephalopathy: a case report and literature review.
Topics: Adolescent; Adult; Aged; Brain; Child; Child, Preschool; Female; Humans; Infant; Magnetic Resonance | 2017 |
Nonalcoholic Wernicke's encephalopathy.
Topics: Dysarthria; Emergency Service, Hospital; Follow-Up Studies; Humans; Infusions, Intravenous; Magnetic | 2016 |
3 trials available for thiamine and Seizures
| Article | Year |
|---|---|
Prevention of delirium tremens: use of phenothiazines versus drugs cross-dependent with alcohol.
Topics: Antipsychotic Agents; Biogenic Amines; Brain Chemistry; Chlordiazepoxide; Chlorpromazine; Drug Toler | 1974 |
Treatment of the acute alcohol withdrawal state: a comparison of four drugs.
Topics: Chlordiazepoxide; Chlorpromazine; Clinical Trials as Topic; Humans; Hydroxyzine; Middle Aged; Placeb | 1969 |
Evaluating changes in symptoms during acute alcohol withdrawal.
Topics: Affect; Alcoholism; Chlordiazepoxide; Chlorpromazine; Clinical Trials as Topic; Female; Humans; Hydr | 1971 |
36 other studies available for thiamine and Seizures
| Article | Year |
|---|---|
Thiamine alleviates cognitive impairment and epileptogenesis by relieving brain inflammation in PTZ-induced kindling rat model.
Topics: Animals; Cognitive Dysfunction; Cyclooxygenase 2; Encephalitis; Epilepsy; Kindling, Neurologic; Male | 2022 |
Wernicke encephalopathy with epileptic seizures during pregnancy.
Topics: Adult; Epilepsy; Female; Humans; Korsakoff Syndrome; Magnetic Resonance Imaging; Pregnancy; Seizures | 2022 |
Expanding the spectrum of neonatal-onset AIFM1-associated disorders.
Topics: Apoptosis Inducing Factor; Humans; Infant, Newborn; Male; Mitochondria; Mitochondrial Encephalomyopa | 2023 |
The modulator action of thiamine against pentylenetetrazole-induced seizures, apoptosis, nitric oxide, and oxidative stress in rats and SH-SY5Y neuronal cell line.
Topics: Animals; Anticonvulsants; Antioxidants; Apoptosis; Brain; Caspase 3; Cell Line; Disease Models, Anim | 2021 |
Anti-convulsive Effect of Thiamine and Melatonin Combination in Mice: Involvement of Oxidative Stress.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Male; Melatonin; Mice; Oxidative Stress; Pentylene | 2021 |
Anticonvulsant effects of thiamine on pentylenetetrazole-induced seizure in mice.
Topics: Animals; Anticonvulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Epilep | 2019 |
Case 38-2017. A 20-Year-Old Woman with Seizures and Progressive Dystonia.
Topics: Basal Ganglia Diseases; Biotin; Brain; Carbidopa; Diagnosis, Differential; Drug Combinations; Dyston | 2017 |
Early administration of vitamins B1 and B6 and l-carnitine prevents a second attack of acute encephalopathy with biphasic seizures and late reduced diffusion: A case control study.
Topics: Brain Diseases; Carnitine; Case-Control Studies; Child, Preschool; Diagnosis, Differential; Disease | 2019 |
Clinical signs, MRI features, and outcomes of two cats with thiamine deficiency secondary to diet change.
Topics: Animals; Brain Stem; Cat Diseases; Cats; Cerebellum; Diet; Dietary Supplements; Female; Magnetic Res | 2013 |
Outbreak of thiamine deficiency in cats associated with the feeding of defective dry food.
Topics: Animal Feed; Animals; Cat Diseases; Cats; Diet; Disease Outbreaks; Female; Magnetic Resonance Imagin | 2017 |
Thiamine deficiency in a cat: resolution of MRI abnormalities following thiamine supplementation.
Topics: Animals; Ataxia; Brain; Cat Diseases; Cats; Dietary Supplements; Female; Magnetic Resonance Imaging; | 2010 |
Thiamine-deficient infant formula: what happened and what have we learned?
Topics: Brain Diseases; Food Industry; Germany; Humans; Infant; Infant Formula; Israel; MEDLINE; Quality Con | 2012 |
Wernicke encephalopathy in a non-alcoholic patient with metastatic CNS lymphoma and new-onset occipital lobe seizures.
Topics: Headache; Humans; Lymphoma, B-Cell; Male; Middle Aged; Occipital Lobe; Recurrence; Seizures; Thiamin | 2012 |
Biotin-responsive basal ganglia disease revisited: clinical, radiologic, and genetic findings.
Topics: Atrophy; Basal Ganglia; Basal Ganglia Diseases; Child; Child, Preschool; Chromosome Mapping; Diffusi | 2013 |
Brain ammonia during convulsions in thiamine-deficient mice.
Topics: Ammonia; Animals; Brain; Brain Chemistry; Mice; Seizures; Thiamine; Thiamine Deficiency; Vitamin B D | 1962 |
THIAMINE AS A NICOTINE ANTAGONIST.
Topics: Animals; Antimetabolites; Anura; Blood Pressure; Blood Pressure Determination; Bufonidae; Cats; Dogs | 1963 |
[ACTIVITY OF TISSUE TRANSAMINASES IN CONVULSIONS PRODUCED WITH THIAMINE].
Topics: Alanine Transaminase; Aspartate Aminotransferases; Brain; D-Alanine Transaminase; Liver; Liver Funct | 1963 |
CHRONIC ACIDOSIS DUE TO AN ERROR IN LACTATE AND PYRUVATE METABOLISM. REPORT OF TWO CASES.
Topics: Acetoacetates; Acidosis; Blood; Blood Gas Analysis; Carbohydrate Metabolism; Carbohydrate Metabolism | 1964 |
AN INVESTIGATION ON THE THIAMINE CONTENT OF MOTHER'S MILK IN RELATION TO INFANTILE CONVULSIONS.
Topics: Female; Humans; Infant; Milk, Human; Mothers; Seizures; Thiamine; Toxicology | 1964 |
[PHARMACOLOGICAL STUDIES OF THIAMINEDISULFIDE (TDS) WITH REGARDS TO ITS TOXICITY].
Topics: Mice; Pharmacology; Research; Seizures; Sulfides; Thiamine; Toxicology | 1964 |
[Experiments on intensification of diminution of tetanic convulsions by means of vitamin B1 injections].
Topics: Seizures; Tetanus; Tetanus Toxoid; Thiamine; Vitamin A; Vitamin K; Vitamins | 1949 |
Wernicke's encephalopathy in a patient with schizophrenia.
Topics: Humans; Injections, Intravenous; Leg; Magnetic Resonance Imaging; Male; Malnutrition; Middle Aged; O | 2006 |
Management of alcohol withdrawal.
Topics: Alcohol Withdrawal Delirium; Anti-Anxiety Agents; Benzodiazepines; Humans; Psychoses, Alcoholic; Sei | 1982 |
Recognition and treatment of acute alcohol withdrawal syndromes.
Topics: Acute Disease; Alcohol Withdrawal Delirium; Alcoholism; Benzodiazepines; Chloral Hydrate; Ethanol; F | 1984 |
Thiamine deficiency in the cat leads to severe learning deficits and to widespread neuroanatomical damage.
Topics: Animals; Brain; Cats; Discrimination Learning; Female; Male; Mental Recall; Motor Activity; Pyrithia | 1982 |
Extracellular glutamate is increased in thalamus during thiamine deficiency-induced lesions and is blocked by MK-801.
Topics: Amino Acids; Animals; Dizocilpine Maleate; Extracellular Space; Hippocampus; Male; Microdialysis; Py | 1993 |
Lead induced thiamine deficiency in the brain decreased the threshold of electroshock seizure in rat.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Electroshock; Female; Lead; Rats; Rats, Wistar; Se | 1999 |
Thiamin-responsive maple syrup urine disease: seizures after 7 years of satisfactory metabolic control.
Topics: Amino Acids, Branched-Chain; Child; Electroencephalography; Female; Humans; Maple Syrup Urine Diseas | 2001 |
The B vitamins and vitamin C in human nutrition. I. General considerations and 'obligatory' B vitamins.
Topics: Amino Acids; Anemia, Hypochromic; Ascorbic Acid; Diet; Humans; Nutritional Physiological Phenomena; | 1979 |
Alcohol intoxication and the alcohol withdrawal syndrome.
Topics: Alcoholic Intoxication; Alcoholism; Benzodiazepines; Chlordiazepoxide; Hallucinations; Humans; Pheny | 1978 |
Is calcium deficiency related to thiamine-dependent neuropathy in pigeon?
Topics: Animals; Calcium; Calcium, Dietary; Columbidae; Magnesium; Nervous System Diseases; Seizures; Telenc | 1975 |
Convulsions.
Topics: Anticonvulsants; Emergency Medical Services; Family Practice; Glucose; Humans; Medical History Takin | 1986 |
Prevention of alcohol withdrawal seizures: the roles of diphenylhydantoin and chlordiazepoxide.
Topics: Alcoholism; Anticonvulsants; Chlordiazepoxide; Electroencephalography; Ethanol; Humans; Neurons; Phe | 1973 |
Effects of forced-feeding on blood levels of pyruvate, glucocorticoids and glucose and on adrenal weight in thiamine-deprived and thiamine antagonist-treated rats.
Topics: Adrenal Glands; Animals; Ataxia; Blood Glucose; Corticosterone; Diet; Feeding and Eating Disorders; | 1969 |
Establishment of the toxic level of nitrofurazone for young liquid-fed calves.
Topics: Animal Feed; Animals; Blood Glucose; Cattle; Cattle Diseases; Diarrhea; Lactates; Male; Nitrofurazon | 1970 |
Production of acetylcholine in rat brain following thiamine deprivation and treatment with thiamine antagonists.
Topics: Acetylcholine; Animals; Ataxia; Brain; Carbon Isotopes; Centrifugation; Chromatography; Diet; Male; | 1969 |