Page last updated: 2024-12-05

1,2-dichloro-1,2,3,3,4,4-hexafluorocyclobutane

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

1,2-dichloro-1,2,3,3,4,4-hexafluorocyclobutane, also known as **HFC-31-10**, is a **highly fluorinated cyclobutane derivative**.

**Structure:**

- It has a four-membered ring (cyclobutane) with two chlorine atoms and six fluorine atoms attached to the ring.

**Importance in Research:**

HFC-31-10 is a valuable compound in various fields, including:

1. **Refrigerant and Air Conditioning:**

- It is a potential replacement for ozone-depleting refrigerants like CFCs and HCFCs.
- Its high thermal stability and low global warming potential make it an attractive alternative.

2. **Solvent and Chemical Intermediate:**

- The high fluorine content gives it excellent chemical inertness and resistance to hydrolysis.
- It can act as a solvent for various organic reactions or be used as a building block in the synthesis of other fluorinated compounds.

3. **Material Science:**

- It can be incorporated into polymers and other materials to enhance their properties, such as thermal stability, chemical resistance, and surface properties.

4. **Pharmaceutical Research:**

- Fluorinated compounds, including HFC-31-10, often exhibit unique properties in pharmaceutical applications.
- They can be used in drug delivery systems, as imaging agents, or as building blocks for drug candidates.

**Note:**

- While promising, the research on HFC-31-10 is still ongoing.
- The exact applications and importance of this compound may evolve as further research progresses.

In summary, 1,2-dichloro-1,2,3,3,4,4-hexafluorocyclobutane is a fascinating compound with various potential applications due to its unique chemical structure and properties. Its importance in research lies in its contribution to developing sustainable alternatives, improving materials, and advancing pharmaceutical research.

Cross-References

ID SourceID
PubMed CID9643
CHEMBL ID446843
SCHEMBL ID1637525
MeSH IDM0239475

Synonyms (17)

Synonym
cyclobutane, 1,2-dichlorohexafluoro-
cyclobutane, 1,2-dichloro-1,2,3,3,4,4-hexafluoro-
1,2-dichlorohexafluorocyclobutane
1,2-dichloro-1,2,3,3,4,4-hexafluorocyclobutane
c4cl2f6
1,2-dichloroperfluorocyclobutane
einecs 206-599-7
brn 1909267
356-18-3
CHEMBL446843
AKOS007930314
FT-0606385
SCHEMBL1637525
mfcd00019259
2-hydroxyphosphonoaceticacid
DTXSID10870514
BS-22660
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID416913Convulsant activity in Sprague-Dawley rat assessed as partial pressure in atmosphere at which convulsion takes place2009European journal of medicinal chemistry, Feb, Volume: 44, Issue:2
Prediction of convulsant activity of gases and vapors.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (34)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's17 (50.00)18.2507
2000's14 (41.18)29.6817
2010's3 (8.82)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 10.64

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index10.64 (24.57)
Research Supply Index3.56 (2.92)
Research Growth Index4.20 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (10.64)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other34 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]