n-methyl-dl-aspartic acid has been researched along with Seizures in 4 studies
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of drugs affecting GABA and glutamic acid receptors on theophylline-induced seizures were investigated in mice." | 7.70 | Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice. ( Amabeoku, GJ, 1999) |
| " Dumont (Polygalaceae) were evaluated for anticonvulsant activity against tonic seizures produced in mice by pentylenetetrazole (PTZ), bicuculline, picrotoxin, and N-methyl-DL-aspartic acid (NMDLA)." | 3.74 | Anticonvulsant activity of Nylandtia spinosa L. Dumont (Polygalaceae) aqueous and methanol leaf extracts in mice. ( Amabeoku, G, 2008) |
| "Water extract of Leonotis leonurus was tested for anticonvulsant activity against seizures produced in mice by pentylenetetrazole, picrotoxin, bicuculline and N-methyl-DL-aspartic acid (intraperitoneal injections)." | 3.71 | Anticonvulsant activity of aqueous extract of Leonotis leonurus. ( Amabeoku, GJ; Bienvenu, E; Eagles, PK; Scott, G; Springfield, EP, 2002) |
| " AR-R 15896AR prevented tonic seizures in rodents for up to 6 to 8 h in response to maximal electroshock (MES), 4-aminopyridine, bicuculline, or strychnine, as well as characteristic seizures following injections of N-methyl-DL-aspartic or kainic acids." | 3.70 | [S]-AR-R 15896AR-A novel anticonvulsant: acute safety, pharmacokinetic and pharmacodynamic properties. ( Balestra, M; Borrelli, AR; Cramer, CL; Eismann, MS; Freedman, LR; Hudzik, TJ; Knowles, MK; Mahmood, N; McCarthy, DJ; Murray, RJ; Palmer, GC; Stagnitto, ML, 1999) |
| "The effects of drugs affecting GABA and glutamic acid receptors on theophylline-induced seizures were investigated in mice." | 3.70 | Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice. ( Amabeoku, GJ, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amabeoku, G | 1 |
| Palmer, GC | 1 |
| Murray, RJ | 1 |
| Cramer, CL | 1 |
| Stagnitto, ML | 1 |
| Knowles, MK | 1 |
| Freedman, LR | 1 |
| Eismann, MS | 1 |
| Mahmood, N | 1 |
| Balestra, M | 1 |
| Borrelli, AR | 1 |
| Hudzik, TJ | 1 |
| McCarthy, DJ | 1 |
| Amabeoku, GJ | 2 |
| Bienvenu, E | 1 |
| Eagles, PK | 1 |
| Scott, G | 1 |
| Springfield, EP | 1 |
4 other studies available for n-methyl-dl-aspartic acid and Seizures
| Article | Year |
|---|---|
Anticonvulsant activity of Nylandtia spinosa L. Dumont (Polygalaceae) aqueous and methanol leaf extracts in mice.
Topics: Animals; Anticonvulsants; Bicuculline; Convulsants; Epilepsy, Generalized; Lethal Dose 50; Male; Met | 2008 |
[S]-AR-R 15896AR-A novel anticonvulsant: acute safety, pharmacokinetic and pharmacodynamic properties.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Bicuculline; Electric Stimulation; Kainic Acid; Male; Mic | 1999 |
Gamma-aminobutyric acid and glutamic acid receptors may mediate theophylline-induced seizures in mice.
Topics: 2-Amino-5-phosphonovalerate; Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Cl | 1999 |
Anticonvulsant activity of aqueous extract of Leonotis leonurus.
Topics: Animals; Anticonvulsants; Bicuculline; Chromatography, High Pressure Liquid; Dose-Response Relations | 2002 |