amitriptyline has been researched along with Seizures in 67 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This work was designed to study the influence of drugs during seizures and status epilepticus (SE) induced by pilocarpine and mortality in adult rats." | 7.73 | Effect of gabaergic, glutamatergic, antipsychotic and antidepressant drugs on pilocarpine-induced seizures and status epilepticus. ( Fonteles, MM; Freitas, RM; Sousa, FC; Viana, GS, 2006) |
| "20 cases of amitriptyline poisoning have been reported." | 7.68 | [Analysis of 20 cases of amitriptyline poisoning]. ( Zhang, X; Zhu, Y, 1992) |
| "In spite of seizures associated with widened electrocardiographic wave (QRS) and right axis deviation on the electrocardiogram (EKG), the correct diagnosis eluded clinicians through a series of hospital admissions." | 5.30 | Amitriptyline-associated seizures in a toddler with Munchausen-by-proxy. ( Cleary, JF; Cristofani, CB; Mullins, ME; Warden, CR, 1999) |
| " Patients with an amitriptyline overdose were more likely to have seizure, coma, tachycardia, a wide QRS or ventricular dysrhythmia, and have received sodium bicarbonate or be intubated." | 3.77 | Incidence of tricyclic antidepressant-like complications after cyclobenzaprine overdose. ( Bebarta, VS; Borys, DJ; Maddry, J; Morgan, DL, 2011) |
| "This work was designed to study the influence of drugs during seizures and status epilepticus (SE) induced by pilocarpine and mortality in adult rats." | 3.73 | Effect of gabaergic, glutamatergic, antipsychotic and antidepressant drugs on pilocarpine-induced seizures and status epilepticus. ( Fonteles, MM; Freitas, RM; Sousa, FC; Viana, GS, 2006) |
| "20 cases of amitriptyline poisoning have been reported." | 3.68 | [Analysis of 20 cases of amitriptyline poisoning]. ( Zhang, X; Zhu, Y, 1992) |
| " The relative safety of different antidepressants has been assessed by looking at answers to the questions: how safe is the drug in overdose; how dangerous are its side effects at therapeutic dose; and does it have any dangerous interactions with other drugs or substances? Based on current data it can be said with reasonable confidence that fluvoxamine, fluoxetine, paroxetine and moclobemide are "safe" antidepressants, and mianserin and trazodone are also "safe" but to a lesser extent (mainly because of hypnosedation)." | 2.39 | Safety of antidepressants. ( de Jonghe, F; Swinkels, JA, 1995) |
| "The absence of neonatal seizures is a robust and important clinical differentiator between KCNQ2 gain-of-function and loss-of-function variants." | 1.72 | KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism. ( Ambrosino, P; Amin, H; Bayat, A; Brilstra, E; Carotenuto, L; Cooper, EC; de Bellescize, J; Devinsky, O; Edery, P; Emrick, L; Goizet, C; Hong, W; Kleefstra, T; Kluger, G; Korenke, GC; Lee, HK; Lesca, G; Mefford, HC; Miceli, F; Michaud, V; Milh, M; Millevert, C; Mosca, I; Møller, RS; Risen, S; Riviello, J; Sands, T; Schrader, D; Soldovieri, MV; Taglialatela, M; Van-Gils, J; Ville, D; Weckhuysen, S; Willemsen, MH, 2022) |
| "Amitriptyline has the potential to cause unusual serious complications, such as abdominal compartment syndrome, irreversible central nervous system disability and lethal arrhythmia." | 1.46 | Unusual complications from amitriptyline intoxication. ( Maruguchi, H; Nakao, A; Nakayama, S; Nishimura, T, 2017) |
| "Pretreatment of amitriptyline, but not diphenhydramine, before scopolamine treatment suppressed the incidence of convulsions." | 1.36 | Scopolamine-induced convulsions in fasted mice after food intake: evaluation of the sedative effect in the suppression of convulsions. ( Baran, E; Enginar, N; Karamürsel, Y; Nurten, A; Zengin, A, 2010) |
| "She was in comatose, had generalized tonic clonic seizure, ventricular tachycardia, and wide QRS complexes." | 1.35 | Treatment of severe amitriptyline intoxication with plasmapheresis. ( Akyüz, M; Aydemir, C; Cabuk, H; Eldes, N; Kolsal, E; Numanoglu, V; Piskin, E; Tekin, IO, 2009) |
| "On examination she was comatose, had ventricular tachycardia and multifocal clonic seizures." | 1.33 | Hemoperfusion in a child with amitriptyline intoxication. ( Canbek, R; Cetinkaya, M; Dönmez, O, 2005) |
| "In spite of seizures associated with widened electrocardiographic wave (QRS) and right axis deviation on the electrocardiogram (EKG), the correct diagnosis eluded clinicians through a series of hospital admissions." | 1.30 | Amitriptyline-associated seizures in a toddler with Munchausen-by-proxy. ( Cleary, JF; Cristofani, CB; Mullins, ME; Warden, CR, 1999) |
| "Midazolam was replaced by saline in the other 12." | 1.28 | Flumazenil in mixed benzodiazepine/tricyclic antidepressant overdose: a placebo-controlled study in the dog. ( Askenasi, R; Leduc, D; Lheureux, P; Vranckx, M, 1992) |
| "On the average, seizures were observed at 40 mg/kg and were seen after desmethylimipramine (50 mg/kg), mianserin (30 mg/kg), amitriptyline (20 mg/kg), imipramine (40 mg/kg), maprotiline (40 mg/kg), and zimelidine (50 mg/kg)." | 1.27 | Comparison of the (pro)convulsive properties of fluvoxamine and clovoxamine with eight other antidepressants in an animal model. ( Bradford, D; Krijzer, F; Snelder, M, 1984) |
| "Convulsive seizures are a potential side effect of antidepressant drug treatment and can be produced by all classes of antidepressants." | 1.27 | Antidepressants and seizure-interactions at the GABA-receptor chloride-ionophore complex. ( Ikeda, M; Knapp, RJ; Malatynska, E; Yamamura, HI, 1988) |
| "According to our convulsion intensity scoring system, these animals have an audiogenic response score (ARS) of 3 and the colony is designated the GEPR-3 colony." | 1.27 | Anticonvulsant drugs and the genetically epilepsy-prone rat. ( Dailey, JW; Jobe, PC, 1985) |
| "Amitriptyline (AMI) was studied in rats snd mice in order to find out whether it had a central antiserotonin activity, previously demonstrated for doxepin - a compound chemically related to AMI." | 1.26 | Central antiserotonin action of amitriptyline. ( Lewandowska, A; Maj, J; Rawtów, A, 1979) |
| " It is concluded that all four drugs show the toxic effects classically associated with tricyclic antidepressants but the relative toxicity amongst these agents varies considerably and is in the order amitriptyline greater than imipramine greater than maprotiline greater than mianserin." | 1.26 | The relative toxicity of amitriptyline, imipramine, maprotiline and mianserin in rabbits in vivo. ( Hughes, IE; Radwan, S, 1979) |
| "could increase the risk of seizures." | 1.26 | [Convulsive incidents and EEG changes during treatment with tricyclic antidepressive agents]. ( Escande, M; Gayral, L; Golberger, E; Jarrige, A; Kulik, J, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (64.18) | 18.7374 |
| 1990's | 11 (16.42) | 18.2507 |
| 2000's | 6 (8.96) | 29.6817 |
| 2010's | 6 (8.96) | 24.3611 |
| 2020's | 1 (1.49) | 2.80 |
| Authors | Studies |
|---|---|
| Martin, LL | 1 |
| Worm, M | 1 |
| Agnew, MN | 1 |
| Kruse, H | 1 |
| Wilker, JC | 1 |
| Geyer, HM | 1 |
| Miceli, F | 1 |
| Millevert, C | 1 |
| Soldovieri, MV | 1 |
| Mosca, I | 1 |
| Ambrosino, P | 1 |
| Carotenuto, L | 1 |
| Schrader, D | 1 |
| Lee, HK | 1 |
| Riviello, J | 1 |
| Hong, W | 1 |
| Risen, S | 1 |
| Emrick, L | 1 |
| Amin, H | 1 |
| Ville, D | 1 |
| Edery, P | 1 |
| de Bellescize, J | 1 |
| Michaud, V | 1 |
| Van-Gils, J | 1 |
| Goizet, C | 1 |
| Willemsen, MH | 1 |
| Kleefstra, T | 1 |
| Møller, RS | 1 |
| Bayat, A | 1 |
| Devinsky, O | 1 |
| Sands, T | 1 |
| Korenke, GC | 1 |
| Kluger, G | 1 |
| Mefford, HC | 1 |
| Brilstra, E | 1 |
| Lesca, G | 1 |
| Milh, M | 1 |
| Cooper, EC | 1 |
| Taglialatela, M | 1 |
| Weckhuysen, S | 1 |
| Nishimura, T | 1 |
| Maruguchi, H | 1 |
| Nakao, A | 1 |
| Nakayama, S | 1 |
| Armitage, MC | 1 |
| Woolfield, KI | 1 |
| Page, CB | 1 |
| Kaicker, J | 1 |
| Bostwick, J | 1 |
| Astuto, M | 1 |
| Minardi, C | 1 |
| Rizzo, G | 1 |
| Gullo, A | 1 |
| Kolsal, E | 1 |
| Tekin, IO | 1 |
| Piskin, E | 1 |
| Aydemir, C | 1 |
| Akyüz, M | 1 |
| Cabuk, H | 1 |
| Eldes, N | 1 |
| Numanoglu, V | 1 |
| Enginar, N | 1 |
| Nurten, A | 1 |
| Karamürsel, Y | 1 |
| Zengin, A | 1 |
| Baran, E | 1 |
| Mutlu, M | 1 |
| Karagüzel, G | 1 |
| Bahat, E | 1 |
| Aksoy, A | 1 |
| Güven, B | 1 |
| Dilber, B | 1 |
| Dilber, E | 1 |
| Bebarta, VS | 1 |
| Maddry, J | 1 |
| Borys, DJ | 1 |
| Morgan, DL | 1 |
| SUNSHINE, P | 1 |
| YAFFE, SJ | 1 |
| ADNER, M | 1 |
| OLSSON, KE | 1 |
| SCHAERER, K | 1 |
| STILLE, G | 1 |
| SAYERS, A | 1 |
| Dönmez, O | 1 |
| Cetinkaya, M | 1 |
| Canbek, R | 1 |
| Deegan, C | 1 |
| O'Brien, K | 1 |
| Shinya, H | 1 |
| Hakoda, S | 1 |
| Kinouchi, S | 1 |
| Freitas, RM | 1 |
| Sousa, FC | 1 |
| Viana, GS | 1 |
| Fonteles, MM | 1 |
| Dalessio, DJ | 1 |
| Lehmann, A | 1 |
| Steel, CM | 1 |
| O'Duffy, J | 1 |
| Brown, SS | 1 |
| Gupta, ML | 1 |
| Gupta, TK | 1 |
| Bhargava, KP | 1 |
| Trimble, MR | 1 |
| Krijzer, F | 1 |
| Snelder, M | 1 |
| Bradford, D | 1 |
| Jimenez, MD | 1 |
| Guharoy, S | 1 |
| Sprague, DH | 1 |
| Wolf, S | 1 |
| Aihara, H | 1 |
| Araki, H | 1 |
| Ohzeki, M | 1 |
| Lowry, MR | 1 |
| Dunner, FJ | 1 |
| Swinkels, JA | 1 |
| de Jonghe, F | 1 |
| Tobiansky, RI | 1 |
| Lloyd, GG | 1 |
| Tobiansky, I | 1 |
| Lloyd, G | 1 |
| Hantson, P | 1 |
| Clemessy, JL | 1 |
| Baud, FJ | 1 |
| Nakielny, J | 1 |
| Curran, S | 1 |
| Byrne, A | 1 |
| Silverstone, P | 1 |
| Mullins, ME | 1 |
| Cristofani, CB | 1 |
| Warden, CR | 1 |
| Cleary, JF | 1 |
| Winrow, AP | 1 |
| Vol'f, MSh | 1 |
| Maj, J | 1 |
| Lewandowska, A | 1 |
| Rawtów, A | 1 |
| Koella, WP | 1 |
| Glatt, A | 1 |
| Klebs, K | 1 |
| Dürst, T | 1 |
| Crome, P | 1 |
| Newman, B | 1 |
| Hughes, IE | 1 |
| Radwan, S | 1 |
| Escande, M | 1 |
| Gayral, L | 1 |
| Golberger, E | 1 |
| Jarrige, A | 1 |
| Kulik, J | 1 |
| Carpenter, DC | 1 |
| Beaubien, AR | 1 |
| Mathieu, LF | 1 |
| Hrdina, PD | 1 |
| Share, NN | 1 |
| McFarlane, CS | 1 |
| Lheureux, P | 1 |
| Vranckx, M | 1 |
| Leduc, D | 1 |
| Askenasi, R | 1 |
| Zhu, Y | 1 |
| Zhang, X | 1 |
| Kleinrok, Z | 1 |
| Gustaw, J | 1 |
| Czuczwar, SJ | 1 |
| Malatynska, E | 1 |
| Knapp, RJ | 1 |
| Ikeda, M | 1 |
| Yamamura, HI | 1 |
| Beal, DW | 1 |
| May, RB | 1 |
| Hamilton, TC | 1 |
| Norton, J | 1 |
| Poyser, RH | 1 |
| Thormählen, D | 1 |
| Dailey, JW | 1 |
| Jobe, PC | 1 |
| Weinbroum, A | 1 |
| Heifetz, M | 1 |
| Bursztein, S | 1 |
| Houghton, AW | 1 |
| Rasmussen, J | 1 |
| Rapp, MS | 1 |
| Betts, TA | 1 |
| Kalra, PL | 1 |
| Wallach, MB | 2 |
| Winters, WD | 2 |
| Mandell, AJ | 2 |
| Spooner, CE | 2 |
| Shimizu, M | 1 |
| Hirooka, T | 1 |
| Karasawa, T | 1 |
| Masuda, Y | 1 |
| Oka, M | 1 |
| Parkin, JM | 1 |
| Fraser, MS | 1 |
| Ueki, S | 1 |
| Ogawa, N | 1 |
| Watanabe, S | 1 |
| Gomita, Y | 1 |
| Araki, Y | 1 |
| Sedal, L | 1 |
| Korman, MG | 1 |
| Williams, PO | 1 |
| Mushin, G | 1 |
| Brown, TC | 1 |
| Dwyer, ME | 1 |
| Stocks, JG | 1 |
| De Carolis, AS | 1 |
| Ziegler, H | 1 |
| Del Basso, P | 1 |
| Longo, VG | 1 |
| Dobrescu, D | 1 |
| Coeugniet, E | 1 |
| Schuckit, M | 1 |
| Robins, E | 1 |
| Feighner, J | 1 |
| Scharfetter, C | 1 |
2 reviews available for amitriptyline and Seizures
| Article | Year |
|---|---|
Epilepsy, antidepressants, and the role of nomifensine.
Topics: Adult; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Double-Bl | 1984 |
Safety of antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depressive Disorder; Drug In | 1995 |
1 trial available for amitriptyline and Seizures
| Article | Year |
|---|---|
Epilepsy, antidepressants, and the role of nomifensine.
Topics: Adult; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Double-Bl | 1984 |
65 other studies available for amitriptyline and Seizures
| Article | Year |
|---|---|
Synthesis of spiro[isobenzofuran-1(3H),4'-piperidines] as potential central nervous system agents. 6. Synthesis, 13C NMR, and biological evaluation of cis- and trans-4-amino-3'-arylspiro[cyclohexane-1,1'(3'H)-isobenzofuran] derivatives.
Topics: Animals; Antidepressive Agents; Benzofurans; Chemical Phenomena; Chemistry; Drug Synergism; Magnetic | 1981 |
KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism.
Topics: Amitriptyline; Autistic Disorder; Epilepsy; Gain of Function Mutation; Humans; Infant, Newborn; Infa | 2022 |
Unusual complications from amitriptyline intoxication.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Brain Damage, Chronic; Coma; Humans; Intestinal Obs | 2017 |
Serotonin toxicity caused by the interaction of fentanyl and serotonergic medications.
Topics: Amitriptyline; Anesthetics, Intravenous; Antidepressive Agents, Tricyclic; Citalopram; Drug Interact | 2016 |
Co-ingestion of tricyclic antidepressants with selective norepinephrine reuptake inhibitors: Overdose in the emergency department.
Topics: Adolescent; Amitriptyline; Antidepressive Agents, Tricyclic; Consciousness; Depression; Desvenlafaxi | 2016 |
Unexplained seizures in an infant.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Female; Humans; Infant; Mothers; Munchausen Syndrom | 2009 |
Treatment of severe amitriptyline intoxication with plasmapheresis.
Topics: Amitriptyline; Child, Preschool; Coma; Drug Overdose; Female; Humans; Plasmapheresis; Poisoning; Sei | 2009 |
Scopolamine-induced convulsions in fasted mice after food intake: evaluation of the sedative effect in the suppression of convulsions.
Topics: Amitriptyline; Animals; Body Weight; Chlorpromazine; Diphenhydramine; Eating; Food Deprivation; Hypn | 2010 |
Charcoal hemoperfusion in an infant with supraventricular tachycardia and seizures secondary to amitriptyline intoxication.
Topics: Amitriptyline; Antidepressive Agents; Charcoal; Hemoperfusion; Humans; Infant; Male; Seizures; Tachy | 2011 |
Incidence of tricyclic antidepressant-like complications after cyclobenzaprine overdose.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Chi-Square Distributio | 2011 |
AMITRIPTYLINE POISONING. CLINICAL AND PATHOLOGICAL FINDINGS IN A FATAL CASE.
Topics: Amitriptyline; Amobarbital; Antidepressive Agents; Apnea; Arrhythmias, Cardiac; Coma; Dialysis; Flui | 1963 |
[ON AMITRIPTYLINE POISONING].
Topics: Amitriptyline; Bipolar Disorder; Blood Pressure Determination; Electrocardiography; Electroencephalo | 1964 |
[TOXICITY STUDIES WITH AMITRIPTYLINE. THERAPEUTIC GUIDE LINES FROM EXPERIMENTAL STUDIES].
Topics: Amitriptyline; Chlordiazepoxide; Dogs; Electrocardiography; Mice; Parasympathomimetics; Pharmacology | 1965 |
THE EFFECT OF ANTIDEPRESSANT DRUGS ON THE CONVULSIVE EXCITABILITY OF BRAIN STRUCTURES.
Topics: Amitriptyline; Animals; Antidepressive Agents; Caudate Nucleus; Cerebral Cortex; Electric Stimulatio | 1964 |
Hemoperfusion in a child with amitriptyline intoxication.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Coma; Electric Countershock; Female; Hemoperfusion; | 2005 |
Amitriptyline poisoning in a 2-year old.
Topics: Adrenergic beta-Agonists; Amitriptyline; Analgesics, Non-Narcotic; Anticonvulsants; Blood Gas Analys | 2006 |
[Plasma drug levels in amitriptyline overdose patient with complicated delayed cardiac arrhythmia and convulsions].
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Drug Overdose; Female; | 2006 |
Effect of gabaergic, glutamatergic, antipsychotic and antidepressant drugs on pilocarpine-induced seizures and status epilepticus.
Topics: Amines; Amitriptyline; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tri | 2006 |
Chronic pain syndromes and disordered cortical inhibition: effects of tricyclic compounds.
Topics: Amitriptyline; Animals; Anticonvulsants; Cerebral Cortex; Humans; Imipramine; Mice; Pain; Paresthesi | 1967 |
Audiogenic seizures data in mice supporting new theories of biogenic amines mechanisms in the central nervous system.
Topics: Amitriptyline; Animals; Brain; Hormones; Imipramine; Indoles; Isocarboxazid; Mice; Nialamide; Norepi | 1967 |
Clinical effects and treatment of imipramine and amitriptyline poisoning in children.
Topics: Accident Prevention; Amitriptyline; Blood Gas Analysis; Child; Chlorpromazine; Electrocardiography; | 1967 |
Central anticholinergic activity of imipramine and allied drugs.
Topics: Amitriptyline; Animals; Atropine; Carbachol; Desipramine; Female; Imipramine; Male; Mice; Parasympat | 1967 |
Comparison of the (pro)convulsive properties of fluvoxamine and clovoxamine with eight other antidepressants in an animal model.
Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Disease Models, Animal; Dose-Response Re | 1984 |
Tricyclic-induced seizure activity.
Topics: Adult; Amitriptyline; Humans; Male; Seizures | 1983 |
Enflurane seizures in patients taking amitriptyline.
Topics: Adult; Amitriptyline; Carbon Dioxide; Drug Interactions; Enflurane; Female; Humans; Male; Seizures | 1982 |
Hippocampal kindling and effects of antiepileptic drugs.
Topics: Amitriptyline; Amygdala; Animals; Anticonvulsants; Chlorpromazine; Diazepam; Electric Stimulation; E | 1982 |
Seizures during tricyclic therapy.
Topics: Adolescent; Adult; Aged; Amitriptyline; Depressive Disorder; Electroencephalography; Epilepsy; Femal | 1980 |
ECT seizure threshold and fluoxetine.
Topics: Amitriptyline; Combined Modality Therapy; Depressive Disorder; Drug Therapy, Combination; Electrocon | 1995 |
Withdrawal syndrome following midazolam infusion.
Topics: Adult; Amitriptyline; Drug Overdose; Female; Humans; Midazolam; Seizures; Substance Withdrawal Syndr | 1995 |
Seizures and antidepressants.
Topics: Amitriptyline; Antidepressive Agents; Depressive Disorder; Fluoxetine; Humans; Risk Factors; Seizure | 1994 |
Tricyclic-induced seizures and absent ECT response.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Doxepin; Electroconvulsive The | 1994 |
Tricyclic-induced seizures and absent ECT response.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Electroconvulsive Thera | 1993 |
Amitriptyline-associated seizures in a toddler with Munchausen-by-proxy.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Caregivers; Child, Preschool; Electrocardiography; | 1999 |
Amitriptyline-associated seizures in a toddler with Munchausen-by-proxy.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Humans; Infant; Munchausen Syndrome by Proxy; Poiso | 1999 |
[Psychotropic drugs in the clinical picture of epilepsy (review of the literature)].
Topics: Amitriptyline; Animals; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Carbamazepine; C | 1975 |
Central antiserotonin action of amitriptyline.
Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Behavior, Animal; Central Nervous System; Decerebrate S | 1979 |
Epileptic phenomena induced in the cat by the antidepressants maprotiline, imipramine, clomipramine, and amitriptyline.
Topics: Amitriptyline; Animals; Anthracenes; Cats; Cerebral Cortex; Clomipramine; Electroencephalography; Ev | 1979 |
The problem of tricyclic antidepressant poisoning.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Child, Preschool; C | 1979 |
The relative toxicity of amitriptyline, imipramine, maprotiline and mianserin in rabbits in vivo.
Topics: Amitriptyline; Anesthesia; Animals; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Behavior | 1979 |
[Convulsive incidents and EEG changes during treatment with tricyclic antidepressive agents].
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clomipramine; Electroencephalography; | 1976 |
Letter: Amitriptyline and imipramine poisoning in children.
Topics: Amitriptyline; Animals; Antidotes; Humans; Imipramine; Phenytoin; Poisoning; Rats; Seizures | 1975 |
Cyclobenzaprine: novel centrally acting skeletal muscle relaxant.
Topics: Amitriptyline; Animals; Anticonvulsants; Ataxia; Cats; Chlorpromazine; Decerebrate State; Diazepam; | 1975 |
Flumazenil in mixed benzodiazepine/tricyclic antidepressant overdose: a placebo-controlled study in the dog.
Topics: Amitriptyline; Animals; Arrhythmias, Cardiac; Dogs; Drug Interactions; Drug Overdose; Electrocardiog | 1992 |
[Analysis of 20 cases of amitriptyline poisoning].
Topics: Adult; Amitriptyline; Female; Humans; Male; Middle Aged; Physostigmine; Poisoning; Seizures | 1992 |
Influence of antidepressant drugs on seizure susceptibility and the anticonvulsant activity of valproate in mice.
Topics: Amitriptyline; Animals; Desipramine; Dose-Response Relationship, Drug; Electroshock; Imipramine; Mal | 1991 |
Antidepressants and seizure-interactions at the GABA-receptor chloride-ionophore complex.
Topics: Amitriptyline; Animals; Antidepressive Agents; Cerebral Cortex; Chlorides; Desipramine; gamma-Aminob | 1988 |
Accidental amitriptyline poisoning in a toddler.
Topics: Accidents, Home; Amitriptyline; Combined Modality Therapy; Female; Humans; Infant; Seizures | 1989 |
Comparison of some effects of paroxetine with amitriptyline on the cardiovascular system in animals.
Topics: Amitriptyline; Animals; Antidepressive Agents; Cats; Drug Evaluation, Preclinical; Electrocardiograp | 1986 |
Anticonvulsant drugs and the genetically epilepsy-prone rat.
Topics: Acoustic Stimulation; Amitriptyline; Animals; Anticonvulsants; Carbamazepine; Desipramine; Disease M | 1985 |
[Poisoning by tricyclic antidepressants and antidotes].
Topics: Adolescent; Amitriptyline; Female; Humans; Phenytoin; Physostigmine; Seizures; Suicide, Attempted; T | 1985 |
Convulsions precipitated by amitriptyline.
Topics: Adult; Amitriptyline; Electroencephalography; Epilepsy; Humans; Male; Seizures | 1971 |
Amitriptyline and imipramine poisoning.
Topics: Adult; Amitriptyline; Humans; Imipramine; Male; Neurologic Manifestations; Phenobarbital; Seizures | 1965 |
Epileptic fits and amitriptyline.
Topics: Amitriptyline; Diazepam; Infusions, Parenteral; Injections, Intramuscular; Seizures | 1968 |
Epileptic fits and amitriptyline.
Topics: Amitriptyline; Humans; Seizures | 1968 |
A correlation of EEG, reticular multiple unit activity and gross behavior following various antidepressant agents in the cat. IV.
Topics: Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Cats; Chlorpromazine; Desipramine; | 1969 |
Pharmacological evaluation of 3-(N-3,3-diphenylpropyl-N-methyl)-aminopropan-1-ol-hydrochloride (PF-82), a new type of antidepressant drug.
Topics: Amitriptyline; Animals; Antidepressive Agents; Cats; Chick Embryo; Dogs; Drug Antagonism; Drug Evalu | 1974 |
Poisoning as a complication of enuresis.
Topics: Amitriptyline; Antidepressive Agents; Child, Preschool; Enuresis; Humans; Imipramine; Ipecac; Nortri | 1972 |
[Psychopharmacological effects of doxepin hydrochloride].
Topics: Amitriptyline; Amphetamine; Animals; Behavior, Animal; Blepharoptosis; Body Temperature; Brain Chemi | 1972 |
Overdosage of tricyclic antidepressants. A report of two deaths and a prospective study of 24 patients.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents; Arrhythmias, Cardiac; Bundle-Branch Block; | 1972 |
Antidepressant overdosage in children--a new menace.
Topics: Accidents, Home; Adolescent; Amitriptyline; Antidepressive Agents; Arrhythmias, Cardiac; Child; Chil | 1971 |
Central effects of 6-hydroxydopamine.
Topics: Amantadine; Amitriptyline; Amphetamine; Animals; Behavior, Animal; Brain; Brain Chemistry; Desiprami | 1971 |
[Anticonvulsant action of imipramine and imitriptyline associated with phenobarbital, phenytoin and diazepam].
Topics: Amitriptyline; Animals; Anticonvulsants; Diazepam; Electroshock; Imipramine; Mice; Pentylenetetrazol | 1970 |
Tricyclic antidepressants and monoamine oxidase inhibitors.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amitriptyline; Animals; Depression; Desipramine; Drug | 1971 |
A neuropharmacological comparison of some tricyclic anti-depressant agents.
Topics: Amitriptyline; Animals; Behavior, Animal; Cats; Electroencephalography; Imipramine; Seizures; Sleep; | 1968 |
[Poisoning with an antidepressive agent. Status epilepticus in suicidal amitriptyline intoxication. Remarks on the neurology of severe poisonings].
Topics: Amitriptyline; Antidepressive Agents; Epilepsy; Humans; Neurologic Manifestations; Pupil; Reflex, St | 1965 |