1-amino-1,3-dicarboxycyclopentane has been researched along with Seizures in 14 studies
*Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 13 (92.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bond, A; Campbell, JB; Griffey, K; Howe, T; Johnson, BG; Lodge, D; Monn, JA; Paschal, JW; Salhoff, CR; Schoepp, DD; Spangle, LA; Tizzano, JP; Valli, MJ; Wright, RA | 1 |
| Lancaster, B; Wheal, HV | 1 |
| Griffey, KI; Schoepp, DD; Tizzano, JP | 1 |
| Klitgaard, H; Laudrup, P | 2 |
| Mortensen, M; Suzdak, PD; Thomsen, C | 1 |
| Fix, AS; Griffey, KI; Helton, DR; Johnson, JA; Schoepp, DD; Tizzano, JP | 1 |
| Fix, AS; McDonald, JW; Schoepp, DD; Tizzano, JP | 1 |
| Camón, L; de Vera, N; Martínez, E; Vives, P | 1 |
| Al-Ghoul, WM; Greenwood, RS; Meeker, RB | 1 |
| Dalby, NO; Thomsen, C | 1 |
| Akiyama, K; Daigen, A; Itoh, T; Kohira, I; Otsuki, S; Ujike, H; Yamada, N | 1 |
| Sacaan, AI; Schoepp, DD | 1 |
| Johnson, BG; Johnston, MV; McDonald, JW; Salhoff, CR; Schoepp, DD | 1 |
14 other study(ies) available for 1-amino-1,3-dicarboxycyclopentane and Seizures
| Article | Year |
|---|---|
Synthesis of the four isomers of 4-aminopyrrolidine-2,4-dicarboxylate: identification of a potent, highly selective, and systemically-active agonist for metabotropic glutamate receptors negatively coupled to adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Anticonvulsants; Cerebral Cortex; Colforsin; Cyclic AMP; Excitatory Amino Acid Agonists; Glutamic Acid; Humans; Hydrogen Bonding; Limbic System; Mice; Models, Molecular; Molecular Structure; Proline; Rats; Receptors, Metabotropic Glutamate; Seizures; Spinal Cord; Stereoisomerism | 1996 |
A comparative histological and electrophysiological study of some neurotoxins in the rat hippocampus.
Topics: Afferent Pathways; Animals; Cycloleucine; Dose-Response Relationship, Drug; Evoked Potentials; Hippocampus; Kainic Acid; Male; Nerve Degeneration; Neurons; Neurotoxins; Rats; Rats, Inbred Strains; Seizures; Synaptic Transmission | 1982 |
Receptor subtypes linked to metabotropic glutamate receptor agonist-mediated limbic seizures in mice.
Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Cycloleucine; Dose-Response Relationship, Drug; Functional Laterality; Limbic System; Male; Mice; Mice, Inbred Strains; Microinjections; Models, Neurological; Neurotoxins; Phosphoserine; Receptors, Metabotropic Glutamate; Seizures; Stereoisomerism | 1995 |
Metabotropic and ionotropic excitatory amino acid receptor agonists induce different behavioral effects in mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Cycloleucine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ibotenic Acid; Kainic Acid; Male; Mice; N-Methylaspartate; Quinoxalines; Quisqualic Acid; Receptors, Glutamate; Seizures | 1993 |
Metabotropic excitatory amino acid receptor agonists selectively potentiate behavioral effects induced by ionotropic excitatory amino acid receptor agonists in mice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Cycloleucine; Drug Synergism; Injections, Intraventricular; Kainic Acid; Male; Mice; N-Methylaspartate; Neurotoxins; Pentylenetetrazole; Receptors, Glutamate; Seizures | 1993 |
The effect of lorazepam tolerance and withdrawal on metabotropic glutamate receptor function.
Topics: Animals; Cerebral Cortex; Cyclic AMP; Cycloleucine; Drug Tolerance; Hydrolysis; In Vitro Techniques; Lorazepam; Male; Mice; Phosphatidylinositols; Protein Kinases; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Seizures; Substance Withdrawal Syndrome | 1995 |
Intracerebral 1S,3R-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD) produces limbic seizures that are not blocked by ionotropic glutamate receptor antagonists.
Topics: Animals; Anticonvulsants; Cycloleucine; Dose-Response Relationship, Drug; Hippocampus; Injections; Limbic System; Male; Mice; Receptors, Amino Acid; Receptors, Metabotropic Glutamate; Seizures; Signal Transduction; Stereoisomerism; Thalamus | 1993 |
Seizures and brain injury in neonatal rats induced by 1S,3R-ACPD, a metabotropic glutamate receptor agonist.
Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Benzodiazepines; Brain Injuries; Cell Nucleus; Corpus Striatum; Cycloleucine; Dantrolene; Dizocilpine Maleate; Female; Hippocampus; Male; Microscopy, Electron; Neurons; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Seizures; Stereotaxic Techniques | 1993 |
Seizures and neuronal damage induced in the rat by activation of group I metabotropic glutamate receptors with their selective agonist 3,5-dihydroxyphenylglycine.
Topics: Analysis of Variance; Animals; Cerebral Ventricles; Cycloleucine; Excitatory Amino Acid Agonists; Glycine; Infusions, Parenteral; Male; Motor Activity; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Seizures | 1998 |
Kindled seizures increase metabotropic glutamate receptor expression and function in the rat supraoptic nucleus.
Topics: Amygdala; Animals; Calcium; Cerebral Cortex; Cycloleucine; Disease Models, Animal; Epilepsy; Immunohistochemistry; In Situ Hybridization; Kindling, Neurologic; Magnesium; Male; Neurons; Rats; Rats, Long-Evans; Receptors, Metabotropic Glutamate; Seizures; Supraoptic Nucleus | 1998 |
Roles of metabotropic glutamate receptor subtypes in modulation of pentylenetetrazole-induced seizure activity in mice.
Topics: Animals; Cerebral Ventricles; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Indans; Infusions, Parenteral; Male; Mice; Mice, Inbred Strains; Pentylenetetrazole; Reaction Time; Resorcinols; Seizures | 1998 |
Long-lasting enhancement of metabotropic excitatory amino acid receptor-mediated polyphosphoinositide hydrolysis in the amygdala/pyriform cortex of deep prepiriform cortical kindled rats.
Topics: Amygdala; Animals; Cerebral Cortex; Cycloleucine; Electric Stimulation; Hydrolysis; Ibotenic Acid; Isomerism; Kindling, Neurologic; Limbic System; Male; Neurotoxins; Phosphatidylinositol Phosphates; Phosphatidylinositols; Prosencephalon; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Seizures | 1992 |
Activation of hippocampal metabotropic excitatory amino acid receptors leads to seizures and neuronal damage.
Topics: Animals; Behavior, Animal; Biotransformation; Cell Death; Cycloleucine; GTP-Binding Proteins; Hippocampus; Male; Neuronal Plasticity; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Amino Acid; Seizures | 1992 |
In vitro and in vivo pharmacology of trans- and cis-(+-)-1-amino-1,3-cyclopentanedicarboxylic acid: dissociation of metabotropic and ionotropic excitatory amino acid receptor effects.
Topics: Animals; Animals, Newborn; Anticonvulsants; Brain; Choline O-Acetyltransferase; Corpus Striatum; Cycloleucine; Dose-Response Relationship, Drug; Glutamate Decarboxylase; Injections; Ions; Male; Nerve Degeneration; Neurotoxins; Rats; Rats, Inbred Strains; Receptors, Amino Acid; Receptors, Cell Surface; Seizures; Stereoisomerism | 1991 |