thiorphan has been researched along with Seizures in 1 studies
Thiorphan: A potent inhibitor of membrane metalloendopeptidase (ENKEPHALINASE). Thiorphan potentiates morphine-induced ANALGESIA and attenuates naloxone-precipitated withdrawal symptoms.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thiorphan effects were mimicked by substance P (SP) and, in a less potent manner, by neurokinin A." | 1.33 | Thiorphan, a neutral endopeptidase inhibitor used for diarrhoea, is neuroprotective in newborn mice. ( Dournaud, P; Fontaine, RH; Gressens, P; Lebas, F; Lelièvre, V; Leroux, P; Medja, F; Ouimet, T; Rougeot, C; Saria, A, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Medja, F | 1 |
| Lelièvre, V | 1 |
| Fontaine, RH | 1 |
| Lebas, F | 1 |
| Leroux, P | 1 |
| Ouimet, T | 1 |
| Saria, A | 1 |
| Rougeot, C | 1 |
| Dournaud, P | 1 |
| Gressens, P | 1 |
1 other study available for thiorphan and Seizures
| Article | Year |
|---|---|
Thiorphan, a neutral endopeptidase inhibitor used for diarrhoea, is neuroprotective in newborn mice.
Topics: Animals; Animals, Newborn; Caspase 3; Cell Death; Cells, Cultured; Cerebral Cortex; Cerebral Palsy; | 2006 |