Page last updated: 2024-08-08 00:48:19

Galectin-4

A galectin-4 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P56470]

Synonyms

Gal-4;
Antigen NY-CO-27;
L-36 lactose-binding protein;
L36LBP;
Lactose-binding lectin 4

Research

Bioassay Publications (4)

TimeframeStudies on this Protein(%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's3 (75.00)2.80

Compounds (3)

Drugs with Activation Measurements

DrugTaxonomyMeasurementAverage (mM)Bioassay(s)Publication(s)
methyl beta-galactosideHomo sapiens (human)Kd6,050.000044
thiodigalactosideHomo sapiens (human)Kd812.500044
galactalHomo sapiens (human)Kd3,850.000022

Enables

This protein enables 3 target(s):

TargetCategoryDefinition
protein bindingmolecular functionBinding to a protein. [GOC:go_curators]
galactoside bindingmolecular functionBinding to a glycoside in which the sugar group is galactose. [GOC:jl, ISBN:0198506732]
carbohydrate bindingmolecular functionBinding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. [GOC:mah]

Located In

This protein is located in 4 target(s):

TargetCategoryDefinition
extracellular spacecellular componentThat part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. [ISBN:0198547684]
cytosolcellular componentThe part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
plasma membranecellular componentThe membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. [ISBN:0716731363]
collagen-containing extracellular matrixcellular componentAn extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells. [GOC:BHF, GOC:rph, PMID:21123617]

Involved In

This protein is involved in 2 target(s):

TargetCategoryDefinition
antibacterial peptide biosynthetic processbiological processThe chemical reactions and pathways resulting in the formation of an antibacterial peptide. [GOC:add, ISBN:0781735149, PMID:11807545, PMID:15638771]
cell adhesionbiological processThe attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. [GOC:hb, GOC:pf]