Page last updated: 2024-10-17

bupropion and Seizures

bupropion has been researched along with Seizures in 103 studies

Bupropion: A propiophenone-derived antidepressant and antismoking agent that inhibits the uptake of DOPAMINE.
bupropion : An aromatic ketone that is propiophenone carrying a tert-butylamino group at position 2 and a chloro substituent at position 3 on the phenyl ring.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"Sustained-release bupropion (bupropion SR) was first launched in the US in 1997 as an aid to smoking cessation and has since been launched in many other countries."8.81Tolerability and safety of sustained-release bupropion in the management of smoking cessation. ( Aubin, HJ, 2002)
"Bupropion is an effective treatment for major depressive disorder and smoking cessation."8.02Acute dystonia following epileptic seizure after bupropion intoxication. ( Çim, EFA; Kamış, GZ; Kurhan, F, 2021)
" She was determined to be postictal after a witnessed new-onset seizure 4 days after starting bupropion for smoking cessation."7.96New-Onset Seizure in Patient Medicated With Bupropion for Smoking Cessation: A Case Report. ( Lovett, S; Rech, MA; Saffaei, D, 2020)
"Delayed seizures have been reported with overdoses of bupropion extended-release (XL)."7.75Incidence and onset of delayed seizures after overdoses of extended-release bupropion. ( Ekleberry, SE; Kern, P; Klein-Schwartz, W; Kunkel, S; Spiller, H; Starr, P, 2009)
"To ensure safer use of bupropion, health professionals must respect the strict contraindications and warnings about use of this drug in patients with a history of seizures."7.74Serious adverse reactions of bupropion for smoking cessation: analysis of the French Pharmacovigilance Database from 2001 to 2004. ( Beyens, MN; Guy, C; Laporte, S; Mounier, G; Ollagnier, M, 2008)
"Bupropion (amfebutamone) enters maternal milk, with a potential risk of seizures in breast-feeding infants."7.73Bupropion: seizures in an infant exposed through breast-feeding. ( , 2005)
"Bupropion is a relatively new and popular medication with seizures as its major side effect."7.71Bupropion seizure proportion among new-onset generalized seizures and drug related seizures presenting to an emergency department. ( Avasarala, J; Pesola, GR, 2002)
"5 mg/kg) significantly decreased latencies to generalized motor seizures induced 12 h later by the noncompetitive GABAA receptor antagonist picrotoxin (10 mg/kg)."7.68Amphetamine and antidepressant drug effects on GABA- and NMDA-related seizures. ( Borowski, TB; Kirkby, RD; Kokkinidis, L, 1993)
"The relationship between seizure occurrence and use of bupropion was examined on the basis of manufacturer's reports."6.38Seizures and bupropion: a review. ( Davidson, J, 1989)
"The incidence of convulsions in patients receiving tricyclic antidepressants or bupropion was reviewed."6.36Incidence of seizures during treatment with tricyclic antidepressant drugs and bupropion. ( Peck, AW; Stern, WC; Watkinson, C, 1983)
"Bupropion is an atypical antidepressant often used in the treatment of depression, tobacco cessation, seasonal affective disorder, and off label for ADHD."5.72Treatment of status epilepticus and prolonged QT after massive intentional bupropion overdose with lidocaine. ( Robinson, S, 2022)
"She had a seizure and required sedation and intubation."5.62Two Cases of Serotonin Syndrome After Bupropion Overdose Treated With Cyproheptadine. ( Beau, J; Bolton, TA; Carpenter, JE; Kazzi, Z; Kiernan, EA; Murray, BP; Sayers, J; Wolf, MJ; Yeh, M, 2021)
"Bupropion pretreatment attenuated KA-induced neuronal cell death and microglia activation in the CA3 region of the hippocampus."5.39Bupropion attenuates kainic acid-induced seizures and neuronal cell death in rat hippocampus. ( Lin, KC; Wang, CC; Wang, SJ, 2013)
"However, the seizure threshold may be influenced by psychotropic drugs."5.37Partial status epilepticus after electroconvulsive therapy and medical treatment with bupropion. ( Dersch, R; Voderholzer, U; Zwernemann, S, 2011)
"Bupropion is a newer generation antidepressant that is commonly used for treatment of depression and for smoking cessation."5.36Seizures induced by recreational abuse of bupropion tablets via nasal insufflation. ( Kim, D; Steinhart, B, 2010)
"Elderly (> or = 60 years) outpatients with major depressive disorder (DSM-IV criteria) were evaluated in this 6-week multicenter, randomized, double-blind study comparing bupropion SR, 100-300 mg/day, and paroxetine, 10-40 mg/day."5.09Bupropion sustained release versus paroxetine for the treatment of depression in the elderly. ( Ascher, JA; Batey, SR; Donahue, RM; Houser, TL; Settle, EC; Weihs, KL, 2000)
"This prospective 105-site study was conducted to determine the rate of seizures and other serious adverse experiences associated with the therapeutic use of the sustained-release formulation of bupropion (bupropion SR)."5.08A prospective safety surveillance study for bupropion sustained-release in the treatment of depression. ( Ascher, JA; Batey, SR; Billow, AA; Dunner, DL; Johnston, JA; Zisook, S, 1998)
"This trial was conducted to determine the incidence of seizures associated with the use of bupropion."5.07A 102-center prospective study of seizure in association with bupropion. ( Ascher, JA; Davidson, J; Feighner, JP; Johnston, JA; Khayrallah, MA; Lineberry, CG; Stark, P, 1991)
"Seizures of both immediate and delayed onset after ingestion of bupropion SR and bupropion XL formulations are well documented, but are less well characterized after insufflation."4.90An 11-year review of bupropion insufflation exposures in adults reported to the California Poison Control System. ( Albertson, TE; Ford, JB; Lewis, JC; Owen, KP; Sutter, ME, 2014)
"Bupropion hydrochloride is a monocyclic antidepressant which is used in a slow-release formulation as a smoking cessation aid."4.81Zyban-- is there a cause for concern? ( Tracey, JA, 2002)
"Sustained-release bupropion (bupropion SR) was first launched in the US in 1997 as an aid to smoking cessation and has since been launched in many other countries."4.81Tolerability and safety of sustained-release bupropion in the management of smoking cessation. ( Aubin, HJ, 2002)
"Increasing age, seizures, QRS widening, and QTc prolongation were associated with adverse cardiovascular events in bupropion exposures."4.31Clinical and electrocardiographic factors associated with adverse cardiovascular events in bupropion exposures. ( Burns, MM; Feng, C; Monuteaux, M; Simpson, M; Troger, A; Whitledge, JD, 2023)
"Bupropion is an effective treatment for major depressive disorder and smoking cessation."4.02Acute dystonia following epileptic seizure after bupropion intoxication. ( Çim, EFA; Kamış, GZ; Kurhan, F, 2021)
" She was determined to be postictal after a witnessed new-onset seizure 4 days after starting bupropion for smoking cessation."3.96New-Onset Seizure in Patient Medicated With Bupropion for Smoking Cessation: A Case Report. ( Lovett, S; Rech, MA; Saffaei, D, 2020)
"Of the 266 recorded single bupropion overdoses, the most common symptoms were seizures (47."3.96Single-Agent Bupropion Exposures: Clinical Characteristics and an Atypical Cause of Serotonin Toxicity. ( Alsukaiti, WS; Calello, DP; Carpenter, J; Dunkley, C; Kazzi, Z; Kiernan, EA; Moran, TP; Murray, B; Rianprakaisang, T, 2020)
"Bupropion is associated with a dose-dependent increased risk of seizures."3.85Concurrent Electroconvulsive Therapy and Bupropion Treatment. ( Geske, JR; Leung, JG; Murphy, LL; Palmer, BA; Takala, CR, 2017)
"Bupropion overdose commonly causes generalized seizures and central nervous system depression."3.79Delayed bupropion cardiotoxicity associated with elevated serum concentrations of bupropion but not hydroxybupropion. ( Al-Abri, SA; Benowitz, NL; Hayashi, S; Olson, KR; Orengo, JP; Thoren, KL, 2013)
"The incidence of seizures after unintentional bupropion ingestion in children aged < 6 years has been reported as 0."3.76Unintentional ingestion of bupropion in children. ( Baker, SD; Beuhler, M; Bosse, GM; Gray, T; Spiller, HA, 2010)
"Unintentional bupropion pediatric exposures uncommonly report severe clinical effects such as seizures."3.76The outcome of unintentional pediatric bupropion ingestions: a NPDS database review. ( Beuhler, MC; Sasser, HC; Spiller, HA, 2010)
"The risk of dose-dependent seizures is a safety issue with bupropion hydrochloride."3.76Twenty percent of a representative sample of patients taking bupropion have abnormal, asymptomatic electroencephalographic findings. ( Baker, B; D'Empaire, I; Liow, K; Macaluso, M; Preskorn, SH; Zackula, R, 2010)
"Delayed seizures have been reported with overdoses of bupropion extended-release (XL)."3.75Incidence and onset of delayed seizures after overdoses of extended-release bupropion. ( Ekleberry, SE; Kern, P; Klein-Schwartz, W; Kunkel, S; Spiller, H; Starr, P, 2009)
"To ensure safer use of bupropion, health professionals must respect the strict contraindications and warnings about use of this drug in patients with a history of seizures."3.74Serious adverse reactions of bupropion for smoking cessation: analysis of the French Pharmacovigilance Database from 2001 to 2004. ( Beyens, MN; Guy, C; Laporte, S; Mounier, G; Ollagnier, M, 2008)
"Bupropion, an atypical antidepressant commonly used for depression and smoking cessation, is well known to cause seizures in both therapeutic use and overdose, but cardiac effects have been reported as minimal, usually sinus tachycardia."3.74Cardiotoxicity associated with accidental bupropion ingestion in a child. ( Gabrysch, J; Givens, ML, 2007)
"Bupropion (amfebutamone) enters maternal milk, with a potential risk of seizures in breast-feeding infants."3.73Bupropion: seizures in an infant exposed through breast-feeding. ( , 2005)
"Bupropion use is probably associated with an increased risk of seizures, but no evidence was found to suggest that the drug is associated with an increased risk of sudden death."3.73Bupropion and the risk of sudden death: a self-controlled case-series analysis using The Health Improvement Network. ( Britton, J; Farrington, P; Godfrey, C; Hubbard, R; Lewis, S; Smeeth, L; Smith, C; West, J, 2005)
"Bupropion is a relatively new and popular medication with seizures as its major side effect."3.71Bupropion seizure proportion among new-onset generalized seizures and drug related seizures presenting to an emergency department. ( Avasarala, J; Pesola, GR, 2002)
"We report a case of a 26-year-old man who ingested 23 g bupropion, developed seizures and hypoxia, and presented in cardiac arrest."3.69Fatal bupropion overdose. ( Gualtieri, J; Harris, CR; Stark, G, 1997)
"5 mg/kg) significantly decreased latencies to generalized motor seizures induced 12 h later by the noncompetitive GABAA receptor antagonist picrotoxin (10 mg/kg)."3.68Amphetamine and antidepressant drug effects on GABA- and NMDA-related seizures. ( Borowski, TB; Kirkby, RD; Kokkinidis, L, 1993)
"Bupropion is an aminoketone antidepressant."2.72Factors associated with seizure development after bupropion overdose: a review of the toxicology investigators consortium. ( Hendrickson, RG; Lin, AL; Murray, BP; Prather, CT; Rianprakaisang, TN, 2021)
"The incidence of a seizure was less than 1 per 1,000 at usual outpatient doses and less than 1 per 100 at usual inpatient doses."2.65Overview of clinically significant adverse reactions to bupropion. ( Cato, AE; Fleck, RJ; Harto-Truax, N; Manberg, PJ; Miller, LL; Sato, T; Stern, WC; Van Wyck Fleet, J, 1983)
"Bupropion is an effective therapy for smoking cessation and is recommended as first-line treatment in both US and UK guidelines."2.43Bupropion: risks and benefits. ( Ross, S; Williams, D, 2005)
"Bupropion is a relatively new monocyclic antidepressant whose mechanism of action remains unknown."2.41Bupropion overdose in an adolescent. ( Ayers, S; Tobias, JD, 2001)
"Study data demonstrate that seizure incidence, which is a concern with high-dose IR, is substantially lower with the new SR formulation."2.40Bupropion sustained release: side effect profile. ( Settle, EC, 1998)
"The relationship between seizure occurrence and use of bupropion was examined on the basis of manufacturer's reports."2.38Seizures and bupropion: a review. ( Davidson, J, 1989)
"Nomifensine was withdrawn from markets worldwide because of reports of serious hypersensitivity reactions, especially hemolytic anemia, and marketing of bupropion in the United States was delayed after seizures occurred in bulimic patients in clinical trials."2.37Adverse reactions to five new antidepressants. ( Hayes, PE; Kristoff, CA, 1986)
"The incidence of convulsions in patients receiving tricyclic antidepressants or bupropion was reviewed."2.36Incidence of seizures during treatment with tricyclic antidepressant drugs and bupropion. ( Peck, AW; Stern, WC; Watkinson, C, 1983)
"Bupropion is widely used for the treatment of major depressive disorder and for smoking cessation assistance."1.91The role of decision tree and machine learning models for outcome prediction of bupropion exposure: A nationwide analysis of more than 14 000 patients in the United States. ( Abdollahi, J; Goss, F; Mehrpour, O; Saeedi, F; Shirazi, FM; Vohra, V, 2023)
"Bupropion is an atypical antidepressant often used in the treatment of depression, tobacco cessation, seasonal affective disorder, and off label for ADHD."1.72Treatment of status epilepticus and prolonged QT after massive intentional bupropion overdose with lidocaine. ( Robinson, S, 2022)
"Bupropion is an antidepressant with unique mechanisms of action leading to a narrow therapeutic window."1.72Disposition, outcomes, and lengths of stay due to bupropion overdose at a tertiary care center with a medical toxicology service. ( McCabe, DJ; Radke, JB; Wilson, BZ, 2022)
"Bupropion is an antidepressant medication with expanding indications including smoking cessation, weight loss, attention-deficit/hyperactivity disorder, seasonal affective disorder, and amphetamine dependence."1.72The Timing of Clinical Effects of Bupropion Misuse Via Insufflation Reported to a Regional Poison Center. ( McCabe, DJ; McGillis, E; Willenbring, BA, 2022)
"She had a seizure and required sedation and intubation."1.62Two Cases of Serotonin Syndrome After Bupropion Overdose Treated With Cyproheptadine. ( Beau, J; Bolton, TA; Carpenter, JE; Kazzi, Z; Kiernan, EA; Murray, BP; Sayers, J; Wolf, MJ; Yeh, M, 2021)
"Safer agents that do not lower the seizure threshold should be utilized whenever possible."1.62Bupropion With Clozapine: Case Reports of Seizure After Coadministration. ( Botner, B; Hund, M; Schmitz, A, 2021)
"Bupropion is a unique class of antidepressant."1.56Pediatric Bupropion Ingestions in Adolescents vs. Younger Children-a Tale of Two Populations. ( Gosen, J; Levine, M; Offerman, S; Thomas, SH, 2020)
"Bupropion is a commonly used antidepressant, and overdose can lead to both neurologic and cardiovascular toxicity, including agitation, seizure, tachycardia, QT and QRS prolongation, and rhythm disturbances."1.51Pediatric Toxidrome Simulation Curriculum: Bupropion Overdose. ( Burns, R; Hartford, E; Keilman, A; Reid, J; Stone, K; Thomas, A; Uspal, N, 2019)
"It is unknown whether the risk of seizure during therapeutic use differs by drug."1.48Second-generation anti-depressants and risk of new-onset seizures in the elderly. ( Finkelstein, Y; Gomes, T; Juurlink, DN; Li, P; Macdonald, EM; Mamdani, MM, 2018)
"Bupropion is an atypical antidepressant that is structurally similar to amphetamines."1.43Atypical Findings in Massive Bupropion Overdose: A Case Report and Discussion of Psychopharmacologic Issues. ( Jimenez, XF; Kolawole, T; Zhu, Y, 2016)
"Bupropion pretreatment attenuated KA-induced neuronal cell death and microglia activation in the CA3 region of the hippocampus."1.39Bupropion attenuates kainic acid-induced seizures and neuronal cell death in rat hippocampus. ( Lin, KC; Wang, CC; Wang, SJ, 2013)
" Chronic administration of bupropion significantly potentiates the protective activity of lamotrigine, topiramate, and felbamate against maximal electroshock-induced seizures."1.37Low dose of bupropion significantly enhances the anticonvulsant activity of felbamate, lamotrigine and topiramate in mice. ( Bańka, K; Barczyński, B; Buszewicz, G; Mądro, R; Mróz, T; Tutaj, K; Tutka, P; Wielosz, M; Łuszczki, JJ, 2011)
"However, the seizure threshold may be influenced by psychotropic drugs."1.37Partial status epilepticus after electroconvulsive therapy and medical treatment with bupropion. ( Dersch, R; Voderholzer, U; Zwernemann, S, 2011)
"Bupropion and tramadol were discontinued, and seizures did not recur."1.36Which xenobiotic(s) could be responsible for the radiologic findings below? Answer: any proconvulsant xenobiotic, in this case tramadol, bupropion, and nortriptyline. ( Roberts, DJ; Stellpflug, SJ, 2010)
"Bupropion is a newer generation antidepressant that is commonly used for treatment of depression and for smoking cessation."1.36Seizures induced by recreational abuse of bupropion tablets via nasal insufflation. ( Kim, D; Steinhart, B, 2010)
"To estimate the rate of new-onset seizure in ADHD patients in relation to ADHD pharmacotherapy."1.35The effect of pharmacotherapy for attention deficit hyperactivity disorder on risk of seizures in pediatric patients as assessed in an insurance claims database. ( Holdridge, KC; Hornbuckle, K; Johannes, CB; McAfee, AT; Walker, AM, 2008)
"On arrival at hospital seizures arose."1.34Bupropion interference with immunoassays for amphetamines and LSD. ( Skripuletz, T; Vidal, C, 2007)
"Diazepam treatment alone and before cocaine overdose did not interfere with catalase activity."1.33Cocaine alters catalase activity in prefrontal cortex and striatum of mice. ( Aguiar, LM; de Sousa, FC; de Vasconcelos, SM; dos Santos, RS; Lima, VT; Macêdo, DS; Viana, GS, 2005)
"Seizures were dose-dependent, with those having seizures ingesting a significantly higher median dose (P = 0."1.32Bupropion poisoning: a case series. ( Balit, CR; Isbister, GK; Lynch, CN, 2003)
"We suggest that sleep deprivation may add to the risk of bupropion-associated seizures."1.32Seizure associated with sleep deprivation and sustained-release bupropion. ( Duckrow, RB; Oncken, CA, 2003)
"Bupropion is an antidepressant that has recently seen increased usage in smoking cessation."1.32Intentional bupropion overdoses. ( Keyes, DC; Shepherd, G; Velez, LI, 2004)
"We describe a prolonged seizure occurring during the first treatment of a course of ECT in an adult patient receiving long-term bupropion therapy, lithium, and venlafaxine."1.31The combined use of bupropion, lithium, and venlafaxine during ECT: a case of prolonged seizure activity. ( Conway, CR; Nelson, LA, 2001)
"Bupropion is a monocyclic antidepressant structurally related to amphetamine."1.31Bupropion (Zyban) toxicity. ( Ali, I; Casey, PB; Cassidy, N; Tracey, JA, 2002)
"Bupropion is an antidepressant and smoking cessation aid."1.31Bupropion exposures: clinical manifestations and medical outcome. ( Belson, MG; Kelley, TR, 2002)
"Seizure is the primary adverse reaction associated with bupropion overdoses."1.30ECG conduction delays associated with massive bupropion overdose. ( Paris, PA; Saucier, JR, 1998)
"Bupropion is a novel new antidepressant without the undesirable anticholinergic, cardiotoxic, sedative, or sexual side effects of other available antidepressants."1.27A case of bupropion-induced seizure. ( Fishman, SM; Sheehan, DV; Welch, JB, 1986)

Research

Studies (103)

TimeframeStudies, this research(%)All Research%
pre-19908 (7.77)18.7374
1990's16 (15.53)18.2507
2000's38 (36.89)29.6817
2010's24 (23.30)24.3611
2020's17 (16.50)2.80

Authors

AuthorsStudies
McCabe, DJ2
McGillis, E1
Willenbring, BA1
Radke, JB1
Wilson, BZ1
Robinson, S1
Rodríguez, PM1
Fernández Revuelta, A1
Romeral Jiménez, M1
Parejo Carbonell, B1
Horga Hernández, A1
Ramos García, I1
Polidura Arruga, C1
Garcia-Morales, I1
Mehrpour, O1
Saeedi, F1
Vohra, V1
Abdollahi, J1
Shirazi, FM1
Goss, F1
Simpson, M1
Troger, A1
Feng, C1
Whitledge, JD1
Monuteaux, M1
Burns, MM1
Offerman, S2
Levine, M2
Gosen, J2
Thomas, SH2
Murray, B1
Carpenter, J1
Dunkley, C1
Moran, TP1
Kiernan, EA2
Rianprakaisang, T1
Alsukaiti, WS1
Calello, DP1
Kazzi, Z2
Hartford, E1
Thomas, A1
Keilman, A1
Uspal, N1
Stone, K1
Reid, J1
Burns, R1
Saffaei, D1
Lovett, S1
Rech, MA1
Schmitz, A1
Botner, B1
Hund, M1
Padilla-Jones, A1
Ruha, AM1
Parikh, NS1
Salehi Omran, S1
Kamel, H1
Elkind, MSV1
Willey, JZ1
Murray, BP2
Carpenter, JE1
Sayers, J1
Yeh, M1
Beau, J1
Wolf, MJ1
Bolton, TA1
Kurhan, F1
Kamış, GZ1
Çim, EFA1
Rianprakaisang, TN1
Prather, CT1
Lin, AL1
Hendrickson, RG1
Sathe, AR1
Thiemann, A1
Toulouie, S1
Durant, E1
Herr, J1
Hatch, L1
Sephien, A1
Hanna, K1
Takala, CR1
Leung, JG1
Murphy, LL1
Geske, JR1
Palmer, BA1
Mishra, DK1
Sardesai, U1
Rastogi, P1
Finkelstein, Y2
Macdonald, EM1
Li, P1
Mamdani, MM1
Gomes, T1
Juurlink, DN1
Yang, YC1
Yeh, TC1
Liang, CS1
Lin, KC1
Wang, CC1
Wang, SJ1
Al-Abri, SA1
Orengo, JP1
Hayashi, S1
Thoren, KL1
Benowitz, NL1
Olson, KR1
Stall, N1
Godwin, J1
Juurlink, D1
Lewis, JC1
Sutter, ME1
Albertson, TE1
Owen, KP1
Ford, JB1
Sharma, A1
Thakar, S1
Lavie, CJ1
Garg, J1
Krishnamoorthy, P1
Sochor, O1
Arbab-Zadeh, A1
Lichstein, E1
Castelnovo, A1
Zambrelli, E1
Canevini, MP1
Cavallotti, S1
Scarone, S1
D'Agostino, A1
Weerdenburg, K1
Zhu, Y1
Kolawole, T1
Jimenez, XF1
Spiller, HA3
Schaeffer, SE1
Bosse, GM1
Beuhler, M1
Gray, T1
Baker, SD1
McAfee, AT1
Holdridge, KC1
Johannes, CB1
Hornbuckle, K1
Walker, AM1
Beyens, MN1
Guy, C1
Mounier, G1
Laporte, S1
Ollagnier, M1
Starr, P1
Klein-Schwartz, W1
Spiller, H1
Kern, P1
Ekleberry, SE1
Kunkel, S1
Beuhler, MC1
Sasser, HC1
Kim, D1
Steinhart, B1
Stellpflug, SJ1
Roberts, DJ1
Boora, K1
Cummings, MR1
Marshall, DR1
Macaluso, M1
Zackula, R1
D'Empaire, I1
Baker, B1
Liow, K1
Preskorn, SH1
Barczyński, B2
Buszewicz, G1
Łuszczki, JJ1
Bańka, K1
Tutaj, K1
Mróz, T1
Wielosz, M2
Mądro, R1
Tutka, P2
Dersch, R1
Zwernemann, S1
Voderholzer, U1
Skjei, KL1
Kessler, SK1
Abend, NS1
Takechi, K1
Suemaru, K1
Kawasaki, H1
Araki, H1
Aubin, HJ1
Welsh, CJ1
Doyon, S1
Belson, MG1
Kelley, TR1
Balit, CR1
Lynch, CN1
Isbister, GK1
Park-Wyllie, LY1
Antoniou, T1
Gamarra, M1
Parajuá, JL1
Coughlin, PA1
Birkinshaw, RI1
Oncken, CA1
Duckrow, RB1
Tracey, JA2
Shepherd, G1
Velez, LI1
Keyes, DC1
Chaudron, LH1
Schoenecker, CJ1
Wah, MF1
Wah, LS1
Hubbard, R1
Lewis, S1
West, J1
Smith, C1
Godfrey, C1
Smeeth, L1
Farrington, P1
Britton, J1
Macêdo, DS1
de Vasconcelos, SM1
dos Santos, RS1
Aguiar, LM1
Lima, VT1
Viana, GS1
de Sousa, FC1
Ross, S1
Williams, D1
Solano Remírez, M1
Alvarez Frías, MT1
González Arencibia, C1
Gutiérrez Dubois, J1
Llorente Díaz, B1
Foley, KF1
DeSanty, KP1
Kast, RE1
Givens, ML1
Gabrysch, J1
Vidal, C1
Skripuletz, T1
Rudorfer, MV1
Golden, RN1
Potter, WZ1
Van Wyck Fleet, J1
Manberg, PJ1
Miller, LL1
Harto-Truax, N1
Sato, T1
Fleck, RJ1
Stern, WC2
Cato, AE1
Peck, AW1
Watkinson, C1
Chouinard, G1
Annable, L1
Langlois, R1
Popli, AP1
Tanquary, J1
Borowski, TB1
Kirkby, RD1
Kokkinidis, L1
Gittelman, DK1
Kirby, MG1
Swartz, CM1
Pollock, BG1
Sweet, RA1
Kirshner, M1
Reynolds, CF1
Harris, CR1
Gualtieri, J1
Stark, G1
Settle, EC2
Tilton, P1
Dunner, DL1
Zisook, S1
Billow, AA1
Batey, SR2
Johnston, JA2
Ascher, JA3
Paris, PA1
Saucier, JR1
Hébert, S1
Damaj, MI1
Slemmer, JE1
Carroll, FI1
Martin, BR1
Selvaraj, N1
Drachman, DA1
Ravin, P1
Knorr, JR1
Weihs, KL1
Houser, TL1
Donahue, RM1
Dunlop, H1
Ayers, S1
Tobias, JD1
Mainie, I1
McGurk, C1
McClintock, G1
Robinson, J1
Enns, MW1
Conway, CR1
Nelson, LA1
Cox, A1
Anton, C1
Wooltorton, E1
Cassidy, N1
Casey, PB1
Ali, I1
Pesola, GR1
Avasarala, J1
White, P1
Lineberry, CG1
Davidson, J2
Khayrallah, MA1
Feighner, JP1
Stark, P1
Davidson, JR1
Goldberg, JP1
Hayes, PE1
Kristoff, CA1
Sheehan, DV1
Welch, JB1
Fishman, SM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Acute Efficacy of Bupropion, Sertraline, and Venlafaxine as Adjuvant Treatment to Mood Stabilizers in Bipolar Depression: A Randomized, Double-Blind, Comparative Study[NCT00001483]Phase 275 participants Interventional1995-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

14 reviews available for bupropion and Seizures

ArticleYear
Smoking-cessation pharmacotherapy for patients with stroke and TIA: Systematic review.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2020, Volume: 78

    Topics: Bupropion; Female; Humans; Ischemic Attack, Transient; Observational Studies as Topic; Randomized Co

2020
Factors associated with seizure development after bupropion overdose: a review of the toxicology investigators consortium.
    Clinical toxicology (Philadelphia, Pa.), 2021, Volume: 59, Issue:12

    Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Bupropion; Drug Overdose; Humans;

2021
An 11-year review of bupropion insufflation exposures in adults reported to the California Poison Control System.
    Clinical toxicology (Philadelphia, Pa.), 2014, Volume: 52, Issue:9

    Topics: Adolescent; Adult; Aged; Bupropion; California; Dose-Response Relationship, Drug; Female; Humans; In

2014
Cardiovascular adverse events associated with smoking-cessation pharmacotherapies.
    Current cardiology reports, 2015, Volume: 17, Issue:1

    Topics: Benzazepines; Bupropion; Chest Pain; Dose-Response Relationship, Drug; Humans; Hypertension; Nicotin

2015
Tolerability and safety of sustained-release bupropion in the management of smoking cessation.
    Drugs, 2002, Volume: 62 Suppl 2

    Topics: Bupropion; Clinical Trials as Topic; Consumer Product Safety; Delayed-Action Preparations; Dopamine

2002
Zyban-- is there a cause for concern?
    Expert opinion on drug safety, 2002, Volume: 1, Issue:4

    Topics: Animals; Antidepressive Agents, Second-Generation; Area Under Curve; Bupropion; Drug Overdose; Half-

2002
Bupropion: risks and benefits.
    Expert opinion on drug safety, 2005, Volume: 4, Issue:6

    Topics: Bupropion; Cost-Benefit Analysis; Dopamine Uptake Inhibitors; Humans; Seizures; Smoking Cessation; T

2005
Bupropion: pharmacology and therapeutic applications.
    Expert review of neurotherapeutics, 2006, Volume: 6, Issue:9

    Topics: Antidepressive Agents, Second-Generation; Bupropion; Clinical Trials as Topic; Depressive Disorder;

2006
Second-generation antidepressants.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:3

    Topics: Alprazolam; Amoxapine; Antidepressive Agents; Benzodiazepines; Bupropion; Citalopram; Clinical Trial

1984
Incidence of seizures during treatment with tricyclic antidepressant drugs and bupropion.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:5 Pt 2

    Topics: Antidepressive Agents; Bupropion; Depressive Disorder; Dose-Response Relationship, Drug; Humans; Imi

1983
Bupropion sustained release: side effect profile.
    The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 4

    Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bupropion; Delayed-Actio

1998
Bupropion overdose in an adolescent.
    Pediatric emergency care, 2001, Volume: 17, Issue:2

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Bupropion; Dopamine Uptake Inhibitors; Dr

2001
Seizures and bupropion: a review.
    The Journal of clinical psychiatry, 1989, Volume: 50, Issue:7

    Topics: Adolescent; Adult; Age Factors; Aged; Antidepressive Agents; Body Weight; Bupropion; Cohort Studies;

1989
Adverse reactions to five new antidepressants.
    Clinical pharmacy, 1986, Volume: 5, Issue:6

    Topics: Acute Kidney Injury; Amoxapine; Animals; Antidepressive Agents; Bupropion; Cardiovascular Diseases;

1986

Trials

8 trials available for bupropion and Seizures

ArticleYear
Second-generation antidepressants.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:3

    Topics: Alprazolam; Amoxapine; Antidepressive Agents; Benzodiazepines; Bupropion; Citalopram; Clinical Trial

1984
Overview of clinically significant adverse reactions to bupropion.
    The Journal of clinical psychiatry, 1983, Volume: 44, Issue:5 Pt 2

    Topics: Adult; Aged; Akathisia, Drug-Induced; Ambulatory Care; Antidepressive Agents; Antidepressive Agents,

1983
Bupropion plasma levels and CYP2D6 phenotype.
    Therapeutic drug monitoring, 1996, Volume: 18, Issue:5

    Topics: Aged; Antidepressive Agents, Second-Generation; Bupropion; Cytochrome P-450 CYP2D6; Depressive Disor

1996
A prospective safety surveillance study for bupropion sustained-release in the treatment of depression.
    The Journal of clinical psychiatry, 1998, Volume: 59, Issue:7

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Antidepressive Agents, Second-Gene

1998
Bupropion sustained release versus paroxetine for the treatment of depression in the elderly.
    The Journal of clinical psychiatry, 2000, Volume: 61, Issue:3

    Topics: Aged; Ambulatory Care; Antidepressive Agents, Second-Generation; Bupropion; Comorbidity; Delayed-Act

2000
A 102-center prospective study of seizure in association with bupropion.
    The Journal of clinical psychiatry, 1991, Volume: 52, Issue:11

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bupropion; Depressive Disorder; Drug Administration Sche

1991
Bupropion dosing recommendations.
    The Journal of clinical psychiatry, 1990, Volume: 51, Issue:2

    Topics: Antidepressive Agents; Bupropion; Clinical Trials as Topic; Depressive Disorder; Drug Administration

1990
Bupropion for depression.
    The Medical letter on drugs and therapeutics, 1989, Nov-03, Volume: 31, Issue:804

    Topics: Antidepressive Agents; Bupropion; Clinical Trials as Topic; Depressive Disorder; Drug Interactions;

1989

Other Studies

82 other studies available for bupropion and Seizures

ArticleYear
The Timing of Clinical Effects of Bupropion Misuse Via Insufflation Reported to a Regional Poison Center.
    The Journal of emergency medicine, 2022, Volume: 62, Issue:2

    Topics: Antidepressive Agents, Second-Generation; Bupropion; Humans; Insufflation; Poisons; Seizures

2022
Disposition, outcomes, and lengths of stay due to bupropion overdose at a tertiary care center with a medical toxicology service.
    The American journal of emergency medicine, 2022, Volume: 54

    Topics: Antidepressive Agents, Second-Generation; Bupropion; Drug Overdose; Humans; Seizures; Tertiary Care

2022
Treatment of status epilepticus and prolonged QT after massive intentional bupropion overdose with lidocaine.
    The American journal of emergency medicine, 2022, Volume: 55

    Topics: Adolescent; Antidepressive Agents, Second-Generation; Bupropion; Cardiotoxicity; Drug Overdose; Fema

2022
Tardive myoclonic focal seizures after electroconvulsive therapy, lithium and bupropion treatment
    Epileptic disorders : international epilepsy journal with videotape, 2022, 12-01, Volume: 24, Issue:6

    Topics: Bupropion; Electroconvulsive Therapy; Electroencephalography; Humans; Lithium; Seizures

2022
The role of decision tree and machine learning models for outcome prediction of bupropion exposure: A nationwide analysis of more than 14 000 patients in the United States.
    Basic & clinical pharmacology & toxicology, 2023, Volume: 133, Issue:1

    Topics: Bupropion; Decision Trees; Depressive Disorder, Major; Humans; Machine Learning; Retrospective Studi

2023
Clinical and electrocardiographic factors associated with adverse cardiovascular events in bupropion exposures.
    Clinical toxicology (Philadelphia, Pa.), 2023, Volume: 61, Issue:7

    Topics: Adult; Arrhythmias, Cardiac; Bupropion; Female; Humans; Long QT Syndrome; Male; Retrospective Studie

2023
Pediatric Bupropion Ingestions in Adolescents vs. Younger Children-a Tale of Two Populations.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2020, Volume: 16, Issue:1

    Topics: Adolescent; Age Factors; Antidepressive Agents, Second-Generation; Bupropion; Cardiotoxicity; Child;

2020
Single-Agent Bupropion Exposures: Clinical Characteristics and an Atypical Cause of Serotonin Toxicity.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2020, Volume: 16, Issue:1

    Topics: Adolescent; Adult; Antidepressive Agents, Second-Generation; Bupropion; Cardiotoxicity; Dyskinesia,

2020
Pediatric Toxidrome Simulation Curriculum: Bupropion Overdose.
    MedEdPORTAL : the journal of teaching and learning resources, 2019, 10-25, Volume: 15

    Topics: Adolescent; Antidepressive Agents, Second-Generation; Bupropion; Cardiopulmonary Resuscitation; Clin

2019
New-Onset Seizure in Patient Medicated With Bupropion for Smoking Cessation: A Case Report.
    The Journal of emergency medicine, 2020, Volume: 58, Issue:3

    Topics: Aged; Bupropion; Female; Humans; Seizures; Smoking Cessation

2020
Bupropion With Clozapine: Case Reports of Seizure After Coadministration.
    Journal of pharmacy practice, 2021, Volume: 34, Issue:3

    Topics: Antipsychotic Agents; Bupropion; Clozapine; Female; Humans; Male; Seizures; Smoking Cessation

2021
Bupropion associated seizures following acute overdose: who develops late seizures.
    Clinical toxicology (Philadelphia, Pa.), 2020, Volume: 58, Issue:12

    Topics: Adolescent; Adult; Antidepressive Agents, Second-Generation; Bupropion; Dose-Response Relationship,

2020
Two Cases of Serotonin Syndrome After Bupropion Overdose Treated With Cyproheptadine.
    The Journal of emergency medicine, 2021, Volume: 60, Issue:4

    Topics: Adolescent; Adult; Bupropion; Cyproheptadine; Drug Overdose; Female; Humans; Male; Seizures; Seroton

2021
Acute dystonia following epileptic seizure after bupropion intoxication.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2021, Volume: 42, Issue:10

    Topics: Bupropion; Depressive Disorder, Major; Dystonia; Humans; Seizures; Smoking Cessation

2021
A 19-Year-Old Woman with a History of Depression and Fatal Cardiorespiratory Failure Following an Overdose of Prescribed Bupropion.
    The American journal of case reports, 2021, Jul-26, Volume: 22

    Topics: Adolescent; Adult; Bupropion; Depression; Drug Overdose; Female; Humans; Seizures; Shock, Cardiogeni

2021
27-year-old woman • postpartum seizures • PTSD • history of depression • Dx?
    The Journal of family practice, 2021, Volume: 70, Issue:6

    Topics: Adult; Antidepressive Agents; Bupropion; Citalopram; Depression, Postpartum; Female; Humans; Seizure

2021
Concurrent Electroconvulsive Therapy and Bupropion Treatment.
    The journal of ECT, 2017, Volume: 33, Issue:3

    Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Bupropion; Case-Control Studies; Combined Mod

2017
Seizure secondary to Bupropion extended release preparation: A report.
    Asian journal of psychiatry, 2017, Volume: 30

    Topics: Adolescent; Antidepressive Agents, Second-Generation; Bupropion; Delayed-Action Preparations; Depres

2017
Second-generation anti-depressants and risk of new-onset seizures in the elderly.
    Clinical toxicology (Philadelphia, Pa.), 2018, Volume: 56, Issue:12

    Topics: Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Bupropion; Case-Control Studies;

2018
A case of recurrent seizures: Drug-drug interaction between low-dose clozapine and extended-release bupropion.
    The Australian and New Zealand journal of psychiatry, 2019, Volume: 53, Issue:2

    Topics: Adult; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Bupropion; Clozapine; Delayed

2019
Bupropion attenuates kainic acid-induced seizures and neuronal cell death in rat hippocampus.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Aug-01, Volume: 45

    Topics: Animals; Anticonvulsants; Bupropion; CA3 Region, Hippocampal; Cell Death; Dose-Response Relationship

2013
Delayed bupropion cardiotoxicity associated with elevated serum concentrations of bupropion but not hydroxybupropion.
    Clinical toxicology (Philadelphia, Pa.), 2013, Volume: 51, Issue:10

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Cardiotoxins; Drug Overdose; Electrocard

2013
Bupropion abuse and overdose.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2014, Sep-16, Volume: 186, Issue:13

    Topics: Antidepressive Agents; Bupropion; Drug Overdose; Humans; Seizures; Substance-Related Disorders; Toba

2014
Occipital seizures and visual pseudohallucinations associated with the addition of bupropion to clozapine: a case report.
    Journal of clinical psychopharmacology, 2015, Volume: 35, Issue:1

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Clozapine; Drug Therapy, Combination; El

2015
A 12-year-old girl with seizures after intentional drug overdose. Bupropion overdose.
    Pediatric emergency care, 2015, Volume: 31, Issue:3

    Topics: Antidepressive Agents, Second-Generation; Bupropion; Child; Diagnosis, Differential; Drug Overdose;

2015
Atypical Findings in Massive Bupropion Overdose: A Case Report and Discussion of Psychopharmacologic Issues.
    Journal of psychiatric practice, 2016, Volume: 22, Issue:5

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Drug Overdose; Electrocardiography; Fema

2016
Multiple seizures after bupropion overdose in a small child.
    Pediatric emergency care, 2008, Volume: 24, Issue:7

    Topics: Antidepressive Agents, Second-Generation; Bupropion; Child; Drug Overdose; Emergency Service, Hospit

2008
Unintentional ingestion of bupropion in children.
    The Journal of emergency medicine, 2010, Volume: 38, Issue:3

    Topics: Bupropion; Child, Preschool; Dopamine Uptake Inhibitors; Female; Hallucinations; Humans; Hypertensio

2010
The effect of pharmacotherapy for attention deficit hyperactivity disorder on risk of seizures in pediatric patients as assessed in an insurance claims database.
    Current drug safety, 2008, Volume: 3, Issue:2

    Topics: Adolescent; Adrenergic Uptake Inhibitors; Atomoxetine Hydrochloride; Attention Deficit Disorder with

2008
Serious adverse reactions of bupropion for smoking cessation: analysis of the French Pharmacovigilance Database from 2001 to 2004.
    Drug safety, 2008, Volume: 31, Issue:11

    Topics: Adolescent; Adult; Aged; Angioedema; Antidepressive Agents, Second-Generation; Bupropion; Cerebrovas

2008
Incidence and onset of delayed seizures after overdoses of extended-release bupropion.
    The American journal of emergency medicine, 2009, Volume: 27, Issue:8

    Topics: Adolescent; Adult; Aged; Bupropion; Chi-Square Distribution; Child; Child, Preschool; Dopamine Uptak

2009
The outcome of unintentional pediatric bupropion ingestions: a NPDS database review.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2010, Volume: 6, Issue:1

    Topics: Accidents; Adrenergic Uptake Inhibitors; Adverse Drug Reaction Reporting Systems; Affect; Age Factor

2010
Seizures induced by recreational abuse of bupropion tablets via nasal insufflation.
    CJEM, 2010, Volume: 12, Issue:2

    Topics: Administration, Intranasal; Adult; Antidepressive Agents, Second-Generation; Bupropion; Diagnosis, D

2010
Which xenobiotic(s) could be responsible for the radiologic findings below? Answer: any proconvulsant xenobiotic, in this case tramadol, bupropion, and nortriptyline.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2010, Volume: 6, Issue:1

    Topics: Adult; Analgesics, Opioid; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricycli

2010
Generalized seizure in three adolescents with bupropion overdose.
    Journal of child and adolescent psychopharmacology, 2010, Volume: 20, Issue:2

    Topics: Adolescent; Antidepressive Agents, Second-Generation; Bupropion; Drug Overdose; Female; Humans; Male

2010
Twenty percent of a representative sample of patients taking bupropion have abnormal, asymptomatic electroencephalographic findings.
    Journal of clinical psychopharmacology, 2010, Volume: 30, Issue:3

    Topics: Adult; Age Factors; Brain; Bupropion; Cohort Studies; Electroencephalography; Female; Humans; Male;

2010
Low dose of bupropion significantly enhances the anticonvulsant activity of felbamate, lamotrigine and topiramate in mice.
    European journal of pharmacology, 2011, Jan-15, Volume: 650, Issue:2-3

    Topics: Animals; Anticonvulsants; Brain; Bupropion; Dopamine Uptake Inhibitors; Dose-Response Relationship,

2011
New obesity pill: new hopes, old fears.
    Lancet (London, England), 2010, Dec-18, Volume: 376, Issue:9758

    Topics: Anti-Obesity Agents; Antidepressive Agents, Second-Generation; Bupropion; Cardiovascular Diseases; D

2010
Partial status epilepticus after electroconvulsive therapy and medical treatment with bupropion.
    Pharmacopsychiatry, 2011, Volume: 44, Issue:7

    Topics: Adrenergic Uptake Inhibitors; Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Bupr

2011
Stimulus-induced rhythmic, periodic, or ictal discharges in a 13-year-old girl after an overdose and respiratory arrest.
    Pediatric neurology, 2011, Volume: 45, Issue:5

    Topics: Adolescent; Baclofen; Bupropion; Drug Overdose; Female; Heart Arrest; Humans; Periodicity; Seizures

2011
Regulatory role of the dopamine and norepinephrine transporters in pentylenetetrazol-kindled mice: association with effect of antidepressants.
    European journal of pharmacology, 2011, Dec-30, Volume: 673, Issue:1-3

    Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Atomoxetine Hydrochloride; Bupropion;

2011
Seizure induced by insufflation of bupropion.
    The New England journal of medicine, 2002, Sep-19, Volume: 347, Issue:12

    Topics: Adolescent; Antidepressive Agents, Second-Generation; Bupropion; Humans; Insufflation; Male; Seizure

2002
Bupropion exposures: clinical manifestations and medical outcome.
    The Journal of emergency medicine, 2002, Volume: 23, Issue:3

    Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Antidepressive Agents, Second-Generation; Bupropion

2002
Bupropion poisoning: a case series.
    The Medical journal of Australia, 2003, Jan-20, Volume: 178, Issue:2

    Topics: Accidents, Home; Adult; Australia; Bupropion; Child, Preschool; Dopamine Uptake Inhibitors; Drug Ove

2003
Concurrent use of bupropion with CYP2B6 inhibitors, nelfinavir, ritonavir and efavirenz: a case series.
    AIDS (London, England), 2003, Mar-07, Volume: 17, Issue:4

    Topics: Adult; Aged; Alkynes; Anti-HIV Agents; Antidepressive Agents, Second-Generation; Benzoxazines; Bupro

2003
[Convulsive episode secondary to bupropion in a patient not included in a risk group].
    Atencion primaria, 2003, Feb-28, Volume: 31, Issue:3

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Humans; Male; Risk Factors; Seizures

2003
Zyban: increasing the workload in an accident and emergency department?
    European journal of emergency medicine : official journal of the European Society for Emergency Medicine, 2003, Volume: 10, Issue:1

    Topics: Adult; Aged; Bupropion; Dizziness; Dopamine Uptake Inhibitors; Emergency Service, Hospital; Female;

2003
Seizure associated with sleep deprivation and sustained-release bupropion.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2003, Volume: 5, Issue:1

    Topics: Adult; Bupropion; Delayed-Action Preparations; Humans; Male; Seizures; Sleep Deprivation; Smoking Ce

2003
Bupropion (amfebutamone): French pharmacovigilance data.
    Prescrire international, 2004, Volume: 13, Issue:70

    Topics: Angioedema; Bupropion; Cardiovascular Diseases; France; Humans; Hypersensitivity; Seizures; Smoking

2004
Intentional bupropion overdoses.
    The Journal of emergency medicine, 2004, Volume: 27, Issue:2

    Topics: Adolescent; Adult; Antidepressive Agents, Second-Generation; Bupropion; Child; Drug Overdose; Female

2004
Bupropion and breastfeeding: a case of a possible infant seizure.
    The Journal of clinical psychiatry, 2004, Volume: 65, Issue:6

    Topics: Adult; Antidepressive Agents, Second-Generation; Breast Feeding; Bupropion; Depressive Disorder; Fem

2004
Convulsant and anticonvulsant effects of bupropion in mice.
    European journal of pharmacology, 2004, Sep-19, Volume: 499, Issue:1-2

    Topics: Animals; Anticonvulsants; Bupropion; Convulsants; Dose-Response Relationship, Drug; Electroshock; Ka

2004
Generalized seizure in a Mauritian woman taking bupropion.
    PLoS medicine, 2004, Volume: 1, Issue:1

    Topics: Adult; Bupropion; Dopamine Uptake Inhibitors; Female; Humans; Seizures; Smoking Cessation

2004
Bupropion and the risk of sudden death: a self-controlled case-series analysis using The Health Improvement Network.
    Thorax, 2005, Volume: 60, Issue:10

    Topics: Antidepressive Agents, Second-Generation; Bupropion; Case-Control Studies; Death, Sudden; Female; Hu

2005
Cocaine alters catalase activity in prefrontal cortex and striatum of mice.
    Neuroscience letters, 2005, Oct-14, Volume: 387, Issue:1

    Topics: Adrenergic Uptake Inhibitors; Animals; Anticonvulsants; Bupropion; Catalase; Catecholamines; Cocaine

2005
Bupropion: seizures in an infant exposed through breast-feeding.
    Prescrire international, 2005, Volume: 14, Issue:78

    Topics: Antidepressive Agents, Second-Generation; Breast Feeding; Bupropion; Contraindications; Dopamine Upt

2005
[Convulsions in association with bupropion].
    Anales de medicina interna (Madrid, Spain : 1984), 2005, Volume: 22, Issue:8

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Female; Humans; Seizures; Smoking Cessat

2005
Cardiotoxicity associated with accidental bupropion ingestion in a child.
    Pediatric emergency care, 2007, Volume: 23, Issue:4

    Topics: Bradycardia; Bupropion; Cardiopulmonary Resuscitation; Child, Preschool; Dopamine Uptake Inhibitors;

2007
Bupropion interference with immunoassays for amphetamines and LSD.
    Therapeutic drug monitoring, 2007, Volume: 29, Issue:3

    Topics: Amphetamines; Antidepressive Agents, Second-Generation; Bupropion; Drug Interactions; False Positive

2007
Absence of orthostatic hypotension in depressed patients treated with bupropion.
    Progress in neuro-psychopharmacology, 1981, Volume: 5, Issue:5-6

    Topics: Adult; Aged; Analysis of Variance; Antidepressive Agents; Blood Pressure; Bupropion; Depression; Ele

1981
Antidepressant-associated seizures.
    The Journal of clinical psychiatry, 1994, Volume: 55, Issue:6

    Topics: Antidepressive Agents; Bupropion; Drug Monitoring; Epilepsies, Partial; Humans; Seizures

1994
Amphetamine and antidepressant drug effects on GABA- and NMDA-related seizures.
    Brain research bulletin, 1993, Volume: 30, Issue:5-6

    Topics: Amphetamine; Animals; Antidepressive Agents; Bupropion; Desipramine; Male; Mice; N-Methylaspartate;

1993
A seizure following bupropion overdose.
    The Journal of clinical psychiatry, 1993, Volume: 54, Issue:4

    Topics: Adult; Bupropion; Depressive Disorder; Drug Overdose; Female; Humans; Seizures

1993
Advancing age may inhibit antidepressant-induced seizure.
    The Journal of clinical psychiatry, 1993, Volume: 54, Issue:5

    Topics: Age Factors; Bulimia; Bupropion; Humans; Middle Aged; Seizures

1993
Fatal bupropion overdose.
    Journal of toxicology. Clinical toxicology, 1997, Volume: 35, Issue:3

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Dopamine; Drug Overdose; Fatal Outcome;

1997
Bupropion and guanfacine.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1998, Volume: 37, Issue:7

    Topics: Adrenergic alpha-Agonists; Antidepressive Agents, Second-Generation; Attention Deficit Disorder with

1998
ECG conduction delays associated with massive bupropion overdose.
    Journal of toxicology. Clinical toxicology, 1998, Volume: 36, Issue:6

    Topics: Adult; Antidepressive Agents, Second-Generation; Arrhythmias, Cardiac; Bupropion; Delirium; Drug Ove

1998
Bupropion (Zyban, sustained-release tablets): reported adverse reactions.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1999, Apr-06, Volume: 160, Issue:7

    Topics: Adverse Drug Reaction Reporting Systems; Antidepressive Agents, Second-Generation; Bupropion; Canada

1999
Pharmacological characterization of nicotine's interaction with cocaine and cocaine analogs.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:3

    Topics: Animals; Body Temperature; Bupropion; Cocaine; Discrimination, Psychological; Female; Male; Membrane

1999
Myocardial infarction, seizure and an abnormal head CT scan.
    Postgraduate medical journal, 1999, Volume: 75, Issue:890

    Topics: Bupropion; Contrast Media; Diagnosis, Differential; Dopamine Uptake Inhibitors; Female; Humans; Midd

1999
Bupropion (Zyban, sustained-release tablets): update.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2000, Jan-11, Volume: 162, Issue:1

    Topics: Bupropion; Canada; Dopamine Uptake Inhibitors; Heart Diseases; Humans; Hypoglycemia; Seizures; Smoki

2000
Seizures after buproprion overdose.
    Lancet (London, England), 2001, May-19, Volume: 357, Issue:9268

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Drug Overdose; Female; Follow-Up Studies

2001
Seizure during combination of trimipramine and bupropion.
    The Journal of clinical psychiatry, 2001, Volume: 62, Issue:6

    Topics: Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bupropion; Depressive Di

2001
The combined use of bupropion, lithium, and venlafaxine during ECT: a case of prolonged seizure activity.
    The journal of ECT, 2001, Volume: 17, Issue:3

    Topics: Antidepressive Agents, Second-Generation; Antimanic Agents; Bupropion; Cyclohexanols; Electroconvuls

2001
Safety profile of bupropion for chronic obstructive pulmonary disease.
    Lancet (London, England), 2001, Sep-22, Volume: 358, Issue:9286

    Topics: Bupropion; Clinical Trials as Topic; Dopamine Uptake Inhibitors; Humans; Lung Diseases, Obstructive;

2001
Bupropion (Zyban, Wellbutrin SR): reports of deaths, seizures, serum sickness.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2002, Jan-08, Volume: 166, Issue:1

    Topics: Bupropion; Contraindications; Dopamine Uptake Inhibitors; Humans; Mortality; Seizures; Serum Sicknes

2002
Bupropion (Zyban) toxicity.
    Irish medical journal, 2002, Volume: 95, Issue:1

    Topics: Adult; Antidepressive Agents, Second-Generation; Bupropion; Drug Overdose; Female; Humans; Ireland;

2002
Bupropion seizure proportion among new-onset generalized seizures and drug related seizures presenting to an emergency department.
    The Journal of emergency medicine, 2002, Volume: 22, Issue:3

    Topics: Adult; Alcohol Withdrawal Seizures; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; A

2002
Interaction of intra-articular steroids and bupropion.
    Clinical radiology, 2002, Volume: 57, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Bupropion; Child; Drug Interactions; Humans; Methylprednisolone; Me

2002
Convulsions and hypersensitivity reactions linked to bupropion.
    Prescrire international, 2002, Volume: 11, Issue:58

    Topics: Antidepressive Agents, Second-Generation; Bupropion; Humans; Hypersensitivity; Seizures; Smoking Ces

2002
Bupropion dose, seizures, women, and age.
    The Journal of clinical psychiatry, 1990, Volume: 51, Issue:9

    Topics: Adult; Age Factors; Antidepressive Agents; Bupropion; Dose-Response Relationship, Drug; Female; Huma

1990
A case of bupropion-induced seizure.
    The Journal of nervous and mental disease, 1986, Volume: 174, Issue:8

    Topics: Adult; Agoraphobia; Antidepressive Agents; Anxiety Disorders; Bupropion; Female; Humans; Panic; Prop

1986