Page last updated: 2024-10-31

deet and Seizures

deet has been researched along with Seizures in 10 studies

N,N-diethyl-m-toluamide : A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of m-toluic acid with the nitrogen of diethylamine. First developed by the U.S. Army in 1946 for use by military personnel in insect-infested areas, it is the most widely used insect repellent worldwide.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"An acute toxic interaction has been described, in which sublethal doses of pyridostigmine bromide (PB) and the insect repellent N,N-diethyl-m-toluamide (DEET), when administered concomitantly, resulted in seizures and lethality."7.70Anticonvulsant-resistant seizures following pyridostigmine bromide (PB) and N,N-diethyl-m-toluamide (DEET). ( Chaney, LA; Hume, AS; Rockhold, RW; Wineman, RW, 1999)
"An acute toxic interaction has been described, in which sublethal doses of pyridostigmine bromide (PB) and the insect repellent N,N-diethyl-m-toluamide (DEET), when administered concomitantly, resulted in seizures and lethality."3.70Anticonvulsant-resistant seizures following pyridostigmine bromide (PB) and N,N-diethyl-m-toluamide (DEET). ( Chaney, LA; Hume, AS; Rockhold, RW; Wineman, RW, 1999)
"The DEET Registry is a post-marketing surveillance system to provide systematic and detailed information about medical events temporally associated with DEET use."1.36Adverse events associated with the use of insect repellents containing N,N-diethyl-m-toluamide (DEET). ( Fell, LA; Murphy, JV; Osimitz, TG; Page, B, 2010)
" The objective of this study was to test the hypothesis that the potential toxicity of DEET is high and that available repellents containing DEET, irrespective of their strength, are not safe when applied to children's skin."1.31Toxic encephalopathy associated with use of DEET insect repellents: a case analysis of its toxicity in children. ( Briassoulis, G; Hatzis, T; Narlioglou, M, 2001)
"Although seizures and encephalopathic syndrome have been described with DEET in previous case reports involving topical exposure of pediatric patients, atypical aspects with regard to this case include that this patient was a male (most other case reports involve females), exposure was relatively brief compared with other reports, and the patient developed seizures without a prodrome described in previous reports."1.28Seizure following brief exposure to the insect repellent N,N-diethyl-m-toluamide. ( Kramer, JE; Leikin, JB; Lipscomb, JW, 1992)
"Their common symptoms and signs were coma, seizures, and hypotension occurring within one hour of ingestion."1.27Severe toxic reactions and death following the ingestion of diethyltoluamide-containing insect repellents. ( Tenenbein, M, 1987)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's4 (40.00)18.2507
2000's1 (10.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Osimitz, TG1
Murphy, JV1
Fell, LA1
Page, B1
Garrettson, L1
Chaney, LA1
Rockhold, RW1
Wineman, RW1
Hume, AS1
Briassoulis, G1
Narlioglou, M1
Hatzis, T1
Lipscomb, JW1
Kramer, JE1
Leikin, JB1
Tenenbein, M1
Edwards, DL1
Johnson, CE1
Roland, EH1
Jan, JE1
Rigg, JM1

Other Studies

10 other studies available for deet and Seizures

ArticleYear
Adverse events associated with the use of insect repellents containing N,N-diethyl-m-toluamide (DEET).
    Regulatory toxicology and pharmacology : RTP, 2010, Volume: 56, Issue:1

    Topics: Adolescent; Adult; Age Distribution; Child; Child, Preschool; Consumer Product Safety; DEET; Humans;

2010
Commentary--DEET: caution for children still needed.
    Journal of toxicology. Clinical toxicology, 1997, Volume: 35, Issue:5

    Topics: Adult; Animals; Central Nervous System Diseases; Child; Child, Preschool; DEET; Humans; Infant; Inse

1997
Bug spray worse than the bite?
    Environmental health perspectives, 1994, Volume: 102, Issue:11

    Topics: Blister; DEET; Humans; Insect Repellents; Seizures

1994
Anticonvulsant-resistant seizures following pyridostigmine bromide (PB) and N,N-diethyl-m-toluamide (DEET).
    Toxicological sciences : an official journal of the Society of Toxicology, 1999, Volume: 49, Issue:2

    Topics: Animals; Anticonvulsants; Cholinesterase Inhibitors; DEET; Drug Synergism; Insect Repellents; Male;

1999
Toxic encephalopathy associated with use of DEET insect repellents: a case analysis of its toxicity in children.
    Human & experimental toxicology, 2001, Volume: 20, Issue:1

    Topics: Administration, Topical; Brain Diseases; DEET; Electroencephalography; Humans; Infant; Insect Repell

2001
Seizure following brief exposure to the insect repellent N,N-diethyl-m-toluamide.
    Annals of emergency medicine, 1992, Volume: 21, Issue:3

    Topics: Administration, Topical; Charcoal; Child, Preschool; Decontamination; DEET; Diazepam; Drug Combinati

1992
Seizures temporally associated with use of DEET insect repellent--New York and Connecticut.
    MMWR. Morbidity and mortality weekly report, 1989, Oct-06, Volume: 38, Issue:39

    Topics: Adult; Animals; Benzamides; Bites and Stings; Child; Child, Preschool; Connecticut; DEET; Humans; Ly

1989
Severe toxic reactions and death following the ingestion of diethyltoluamide-containing insect repellents.
    JAMA, 1987, Sep-18, Volume: 258, Issue:11

    Topics: Adolescent; Adult; Benzamides; Coma; DEET; Female; Humans; Hypotension; Infant; Male; Seizures

1987
Insect-repellent-induced toxic encephalopathy in a child.
    Clinical pharmacy, 1987, Volume: 6, Issue:6

    Topics: Aerosols; Ataxia; Benzamides; Brain Diseases; DEET; Drug Combinations; Female; Humans; Infant; Insec

1987
Toxic encephalopathy in a child after brief exposure to insect repellents.
    Canadian Medical Association journal, 1985, Jan-15, Volume: 132, Issue:2

    Topics: Acute Disease; Akathisia, Drug-Induced; Benzamides; Brain Diseases; Child; DEET; Dermatitis, Contact

1985