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fenclonine and Seizures

fenclonine has been researched along with Seizures in 53 studies

Fenclonine: A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"Convulsive responsiveness of O'Grady mice, inbred for susceptibility to audiogenic seizures, was decreased following treatment with the serotonin precursor, 5-hydroxytryptophan, or serotonin depletor, p-chlorophenylalanine."7.65Additive effect of 5-hydroxytryptophan and p-chloro-phenylalanine in preventing audiogenic seizures in inbred mice. ( Alexander, GJ; Kopeloff, LM, 1976)
"In the work reported here, audiogenic seizure susceptibility and brain tryptophan and serotonin concentrations were measured in DBA/2J mice after administration of three doses of L-tryptophan or p-chlorophenylalanine."5.27Audiogenic seizures and brain serotonin after L-tryptophan and p-chlorophenylalanine. ( Lack, DB; Peters, RI, 1985)
" Using the kainic acid model of epilepsy in rats, we tested the effects of serotonin depletion on (1) susceptibility to acute seizures, (2) development of spontaneous recurrent seizures and (3) behavioral and neuroanatomical sequelae of kainic acid treatment."3.85Serotonin depletion increases seizure susceptibility and worsens neuropathological outcomes in kainate model of epilepsy. ( Brazete, CS; Lukoyanov, NV; Luz, LL; Maia, GH; Soares, JI, 2017)
" As a consequence of this increased 5-HT hyperinnervation, En1(cre/+); Otx2(flox/flox) mice were resistant to generalized seizures induced by the glutamate agonist kainic acid (KA)."3.74Serotonin hyperinnervation abolishes seizure susceptibility in Otx2 conditional mutant mice. ( Bozzi, Y; Di Giovannantonio, LG; Simeone, A; Tripathi, PP; Viegi, A; Wurst, W, 2008)
"The effect of the selective 5-hydroxytryptamine1B (5-HT1B) receptor agonist 5-propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine (CP 94253) and the 5-HT1A/1B/1D receptor agonist 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridyl)-1H-indole (RU 24969) in maximal electroshock- and pentylenetetrazol-induced seizures in mice was examined."3.73Anticonvulsant effect of the selective 5-HT1B receptor agonist CP 94253 in mice. ( Chojnacka-Wójcik, E; Nikiforuk, A; Wesołowska, A, 2006)
"The aim of our study was to analyse the possible implication of the serotoninergic system in the pathophysiology and the lethality of audiogenic seizures induced by magnesium deficiency, either by decreasing cerebral serotonin (5-HT) levels (p-chlorophenylalanine) or by increasing 5-HT levels in the brain (5-hydroxytryptophan, L-tryptophan, nialamide, fluoxetine)."3.69Effect of various serotoninergically induced manipulations on audiogenic seizures in magnesium-deficient mice. ( Bac, P; Binet, P; Dewulf, C; Durlach, J; Herrenknecht, C; Pages, N, 1994)
"Fluoxetine, a serotonin (5-HT) reuptake inhibitor, has been documented to exert a protective action against convulsive seizures in animal models, when administered either systemically, or focally into substantia nigra."3.69The anticonvulsant action of fluoxetine in substantia nigra is dependent upon endogenous serotonin. ( Gale, K; Pasini, A; Tortorella, A, 1996)
"The effect of chronic para-chlorphenylalanine (PCPA) treatment was investigated in two different seizure models: the pentylenetetrazole (PTX) seizure model in rats and the kindled seizures from rabbit amygdala."3.66Effect of chronic para-chlorophenylalanine treatment on convulsive-seizure reactions. ( Kacz, D; Lazarova, M; Petkov, V; Roussinov, K; Stach, R; Yanev, S, 1981)
"Convulsive responsiveness of O'Grady mice, inbred for susceptibility to audiogenic seizures, was decreased following treatment with the serotonin precursor, 5-hydroxytryptophan, or serotonin depletor, p-chlorophenylalanine."3.65Additive effect of 5-hydroxytryptophan and p-chloro-phenylalanine in preventing audiogenic seizures in inbred mice. ( Alexander, GJ; Kopeloff, LM, 1976)
"The role of brain monoamines in the anticonvulsant effect of imipramine was investigated in albino rats, against maximal electroshock-induced seizures, by using drugs with well-defined effects on brain monoamines."3.65Role of brain monoamines in the anticonvulsant effect of imipramine in albino rats. ( Bhattacharya, SK; Das, PK; Mukhopadhyay, SN; Reddy, PK, 1976)
"In the work reported here, audiogenic seizure susceptibility and brain tryptophan and serotonin concentrations were measured in DBA/2J mice after administration of three doses of L-tryptophan or p-chlorophenylalanine."1.27Audiogenic seizures and brain serotonin after L-tryptophan and p-chlorophenylalanine. ( Lack, DB; Peters, RI, 1985)
"Both anti-5HT agents shortened convulsion latency in non-stressed animals."1.27Participation of serotonergic mechanisms in the anticonvulsant effect of stress in mice treated with pentylenetetrazol. ( De-Lima, TC; Rae, GA, 1988)
"Lidocaine and procaine seizure thresholds were studied."1.26Alteration of lidocaine- or procaine-induced convulsions by manipulation of brain amines. ( Ciarlone, AE, 1981)
" Chronic administration of 5-HTP 25 mg/kg and femoxetine 15 mg/kg prolonged the duration of behavioral seizures."1.26Serotonergic mechanism in seizures kindled from the rabbit amygdala. ( Kacz, D; Lazarova, MB; Stach, R, 1981)
"hipp seizure developed into motor seizure after establishing secondary epileptogenesis in AM and globys paliidus."1.26A study of psychomotor epilepsy with "kindled" cat preparations. ( Sato, M, 1976)
"Correlation between the kindled seizure susceptibility and brain monoamine levels was investigated in the hippocampal and amygdaloid kindled cats."1.26[Correlation between seizure susceptibility and brain catecholamine levels. An experimental study using a kindling preparation]. ( Mitsunobu, K; Nakashima, T; Otsuki, S; Sato, M, 1976)
"Reserpine enhanced the incidence of seizures, and the effect was reversed by 5-hydroxytryptophan but not by dihydroxyphenylalanine."1.25Effects of aminergic drugs and glutamic acid on audiogenic seizures induced by early exposure to ethanol. ( Ginsburg, BE; Sze, PY; Yanai, J, 1975)

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-199046 (86.79)18.7374
1990's3 (5.66)18.2507
2000's2 (3.77)29.6817
2010's2 (3.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Maia, GH1
Brazete, CS1
Soares, JI1
Luz, LL1
Lukoyanov, NV1
Tripathi, PP1
Di Giovannantonio, LG1
Viegi, A1
Wurst, W1
Simeone, A1
Bozzi, Y1
de Carvalho, RS1
Duarte, FS1
de Lima, TC1
Wesołowska, A1
Nikiforuk, A1
Chojnacka-Wójcik, E1
Katkov, IuA1
Munkenbeck, KE1
Schwark, WS1
Archer, T1
Tandberg, B1
Kästner, I1
Rougerie, A1
Seidel, J1
Koblin, DD1
Little, HJ1
Green, AR1
Daniels, S1
Smith, EB1
Paton, WD1
Ciarlone, AE1
Stach, R2
Lazarova, MB2
Kacz, D2
Cavalheiro, EA1
Elisabetsky, E1
Campos, CJ1
Lazarova, M1
Roussinov, K1
Yanev, S1
Petkov, V1
Vocci, FJ1
Buterbaugh, GG3
Bac, P1
Pages, N1
Herrenknecht, C1
Dewulf, C1
Binet, P1
Durlach, J1
Pasini, A1
Tortorella, A1
Gale, K1
Browning, RA1
Wood, AV1
Merrill, MA1
Dailey, JW1
Jobe, PC3
Yanai, J1
Sze, PY1
Ginsburg, BE1
Georgiev, VP3
Petkova, BP2
Avakian, RM1
Alexander, GJ6
Kopeloff, LM6
Sato, M2
Nakashima, T1
Mitsunobu, K1
Otsuki, S1
London, ED1
Geiger, PF1
Ray, TB1
Woods, TW1
Mims, ME1
Wilkison, DM1
Halpern, LM1
Roussinov, KS1
Yanev, SG1
Thut, PD1
Myslinski, NR1
Bhattacharya, SK2
Mukhopadhyay, SN1
Reddy, PK1
Das, PK1
Hara, S1
Satoh, T1
Kitagawa, H1
Leadbetter, MI1
Parmar, SS2
Peters, RI1
Lack, DB1
De-Lima, TC1
Rae, GA1
Wenger, GR2
Stitzel, RE2
Craig, CR2
Alexander, RB1
De la Torre, JC1
Kawanaga, HM1
Mullan, S1
Azzaro, AJ1
Peters, DA1
Hrdina, PD1
Singhal, RL1
Ling, GM1
Kostowski, W1
Gumulka, W1
Cxlonkowski, A1
Nasello, AG1
Marichich, ES1
Picchioni, AL1
Chin, L1
De Oliveira, LF1
Bretas, AD1
Diaz, PM1
Wada, JA1
Terao, A1
Scholtmeyer, H1
Trapp, WG1
Kamat, UG1
Sheth, UK1

Other Studies

53 other studies available for fenclonine and Seizures

ArticleYear
Serotonin depletion increases seizure susceptibility and worsens neuropathological outcomes in kainate model of epilepsy.
    Brain research bulletin, 2017, Volume: 134

    Topics: Animals; Disease Models, Animal; Disease Susceptibility; Epilepsy; Fenclonine; Hippocampus; Kainic A

2017
Serotonin hyperinnervation abolishes seizure susceptibility in Otx2 conditional mutant mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Sep-10, Volume: 28, Issue:37

    Topics: Analysis of Variance; Animals; Enzyme Inhibitors; Fenclonine; Gene Expression Regulation; Hippocampu

2008
Involvement of GABAergic non-benzodiazepine sites in the anxiolytic-like and sedative effects of the flavonoid baicalein in mice.
    Behavioural brain research, 2011, Aug-01, Volume: 221, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Dehydroepiandrosterone Sulfate; Disease Models, Animal; Dose-Response

2011
Anticonvulsant effect of the selective 5-HT1B receptor agonist CP 94253 in mice.
    European journal of pharmacology, 2006, Jul-10, Volume: 541, Issue:1-2

    Topics: Animals; Anticonvulsants; Benzamides; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; El

2006
[Changes in the predisposition of rats to audiogenic seizures by intervention in monoamine metabolism].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1984, Volume: 70, Issue:4

    Topics: Acoustic Stimulation; Animals; Brain; Disease Susceptibility; Ditiocarb; Dopamine; Fenclonine; Ipron

1984
Serotonergic mechanisms in amygdaloid-kindled seizures in the rat.
    Experimental neurology, 1982, Volume: 76, Issue:2

    Topics: 5-Hydroxytryptophan; Amygdala; Animals; Brain; Female; Fenclonine; Hydroxyindoleacetic Acid; Kindlin

1982
Effects of acute administration of 5-methoxy-N,N-dimethyltryptamine upon the latency and duration of post-decapitation convulsions.
    Acta pharmacologica et toxicologica, 1984, Volume: 55, Issue:3

    Topics: Animals; Fenclonine; Male; Metergoline; Methoxydimethyltryptamines; p-Chloroamphetamine; Rats; Rats,

1984
[Effects of tryptophan and p-chlorophenylalanine on the epileptogenic cobalt focus in the rat].
    Die Pharmazie, 1980, Volume: 35, Issue:7

    Topics: Animals; Anticonvulsants; Cobalt; Drug Implants; Electroencephalography; Fenclonine; Male; Rats; Sei

1980
Brain monoamines and the high pressure neurological syndrome.
    Neuropharmacology, 1980, Volume: 19, Issue:11

    Topics: Animals; Atmospheric Pressure; Biogenic Amines; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide

1980
Alteration of lidocaine- or procaine-induced convulsions by manipulation of brain amines.
    Journal of dental research, 1981, Volume: 60, Issue:2

    Topics: Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain; Dopamine; Droxidopa; Fenclonin

1981
Serotonergic mechanism in seizures kindled from the rabbit amygdala.
    Naunyn-Schmiedeberg's archives of pharmacology, 1981, Volume: 316, Issue:1

    Topics: 5-Hydroxytryptophan; Amygdala; Animals; Fenclonine; Male; Rabbits; Receptors, Serotonin; Seizures

1981
Effect of brain serotonin level on induced hippocampal paroxysmal activity in rats.
    Pharmacology, biochemistry, and behavior, 1981, Volume: 15, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Brain; Electric Stimulation; Electroencephalography; Fenclonine; Hippo

1981
Effect of chronic para-chlorophenylalanine treatment on convulsive-seizure reactions.
    Acta biologica et medica Germanica, 1981, Volume: 40, Issue:3

    Topics: Amygdala; Animals; Brain; Electric Stimulation; Fenclonine; Kinetics; Male; Pentylenetetrazole; Rabb

1981
Hippocampal seizure discharge produced by systemic digitoxigenin is antagonized by reserpine or p-chlorophenylalanine.
    Neuropharmacology, 1982, Volume: 21, Issue:1

    Topics: Animals; Digitoxigenin; Fenclonine; Hippocampus; Male; Rats; Rats, Inbred Strains; Reserpine; Seizur

1982
Effect of various serotoninergically induced manipulations on audiogenic seizures in magnesium-deficient mice.
    Magnesium research, 1994, Volume: 7, Issue:2

    Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Analysis of Variance; Animals; Brain; Fenclonine; Fluoxet

1994
The anticonvulsant action of fluoxetine in substantia nigra is dependent upon endogenous serotonin.
    Brain research, 1996, Jun-10, Volume: 724, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anticonvulsants; Bicuculline; Convulsants; Fencloni

1996
Enhancement of the anticonvulsant effect of fluoxetine following blockade of 5-HT1A receptors.
    European journal of pharmacology, 1997, Oct-01, Volume: 336, Issue:1

    Topics: Acoustic Stimulation; Animals; Anticonvulsants; Brain; Cyclohexylamines; Drug Interactions; Female;

1997
Effects of aminergic drugs and glutamic acid on audiogenic seizures induced by early exposure to ethanol.
    Epilepsia, 1975, Volume: 16, Issue:1

    Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Behavior, Animal; Dihydroxyphenylalanine; Drug I

1975
Effect of p-chlorophenylalanine on the central nervous excitability threshold and on the activity of some central depressants.
    Medical biology, 1975, Volume: 53, Issue:1

    Topics: Animals; Central Nervous System; Depression, Chemical; Fenclonine; Hypnotics and Sedatives; Injectio

1975
Effect of p-chlorophenylalanine (pCPA) and p-bromomethamphetamine (V--111) on the central nervous excitability threshold in mice.
    Polish journal of pharmacology and pharmacy, 1975, Volume: 27, Issue:Suppl

    Topics: Animals; Central Nervous System; Depression, Chemical; Drug Interactions; Fenclonine; Male; Methamph

1975
[Role of the striatum in the influence of serotoninergic substances on the course of corazole seizures in rats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1976, Volume: 82, Issue:7

    Topics: 5-Hydroxytryptophan; Animals; Corpus Striatum; Female; Fenclonine; Male; Pentylenetetrazole; Rats; S

1976
Audiogenic seizures in mice: influence of agents affecting brain serotonin.
    Research communications in chemical pathology and pharmacology, 1976, Volume: 14, Issue:3

    Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Amides; Animals; Behavior, Animal; Brain Chemistry; Fencl

1976
A study of psychomotor epilepsy with "kindled" cat preparations.
    Folia psychiatrica et neurologica japonica, 1976, Volume: 30, Issue:3

    Topics: Amygdala; Animals; Cats; Disease Models, Animal; Dopamine; Electric Stimulation; Electroencephalogra

1976
The effect of p-bromomethamphetamine (V-111), a selective serotoninergic amphetamine, on the convulsive seizure excitability threshold in mice.
    Neuropharmacology, 1976, Volume: 15, Issue:12

    Topics: 5-Hydroxytryptophan; Animals; Fenclonine; Imipramine; Male; Methamphetamine; Mice; Nialamide; Pentyl

1976
Additive effect of 5-hydroxytryptophan and p-chloro-phenylalanine in preventing audiogenic seizures in inbred mice.
    Psychopharmacology communications, 1976, Volume: 2, Issue:5-6

    Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Brain; Drug Synergism; Drug Therapy, Combination

1976
[Correlation between seizure susceptibility and brain catecholamine levels. An experimental study using a kindling preparation].
    No to shinkei = Brain and nerve, 1976, Volume: 28, Issue:5

    Topics: 5-Hydroxytryptophan; Amygdala; Animals; Brain Chemistry; Catecholamines; Cats; Dopamine; Electric St

1976
p-Chlorophenylalanine-mediated decrease in susceptibility to audiogenic seizures in inbred mice.
    Neuropharmacology, 1977, Volume: 16, Issue:6

    Topics: Acoustic Stimulation; Animals; Behavior, Animal; Brain Chemistry; Depression, Chemical; Fenclonine;

1977
The relationship between magnitude of electroshock stimulation and the effects of digitoxigenin, pentylenetetrazol and brain monoamine reduction on electroshock convulsive thresholds.
    Neuropharmacology, 1977, Volume: 16, Issue:9

    Topics: Animals; Biogenic Amines; Brain; Brain Chemistry; Depression, Chemical; Digitoxigenin; Electroshock;

1977
A role for central serotonergic systems in the pattern and intensity of the convulsive response of rats to electroshock.
    Neuropharmacology, 1977, Volume: 16, Issue:10

    Topics: Animals; Brain Chemistry; Digitoxigenin; Electroshock; Fenclonine; Male; Methyltyrosines; Pentylenet

1977
The relative significance of spinal cord norepinephrine and 5-hydroxytryptamine in electrically-induced seizure in the rat.
    Neuropharmacology, 1978, Volume: 17, Issue:3

    Topics: 5,7-Dihydroxytryptamine; Animals; Desipramine; Electric Stimulation; Female; Fenclonine; Hydroxydopa

1978
Anticonvulsive effect of p-chlorophenylalanine in mice on a low magnesium diet.
    Pharmacology, biochemistry, and behavior, 1978, Volume: 8, Issue:3

    Topics: Acoustic Stimulation; Animals; Anticonvulsants; Behavior, Animal; Fenclonine; Magnesium Deficiency;

1978
The role of biogenic amines in amygdalar kindling. I. Local amygdalar afterdischarge.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 211, Issue:1

    Topics: Action Potentials; Amygdala; Animals; Biogenic Amines; Electric Stimulation; Fenclonine; Male; Methy

1979
On some correlations between adrenergic and serotoninergic mechanisms of convulsive-seizure reactivity.
    Polish journal of pharmacology and pharmacy, 1975, Volume: 27, Issue:Suppl

    Topics: Animals; Brain Chemistry; Ditiocarb; Dopamine; Fenclonine; Male; Mice; Norepinephrine; Pentylenetetr

1975
The role of dopamine and serotonin in the prolongation of post-decapitation convulsions in mice.
    Life sciences, 1976, Nov-15, Volume: 19, Issue:10

    Topics: 5-Hydroxytryptophan; Animals; Benserazide; Brain; Decerebrate State; Ditiocarb; Dopamine; Fenclonine

1976
Role of brain monoamines in the anticonvulsant effect of imipramine in albino rats.
    Pharmacology, 1976, Volume: 14, Issue:5

    Topics: Animals; Anticonvulsants; Apomorphine; Catecholamines; Ditiocarb; Dopamine; Drug Interactions; Elect

1976
Suppression of pentylenetetrazol-induced seizures by hydralazine associated with 5-hydroxytryptaminergic system in rat brain.
    Japanese journal of pharmacology, 1987, Volume: 43, Issue:4

    Topics: alpha-Methyltyrosine; Animals; Brain; Fenclonine; Hydralazine; Hydroxyindoleacetic Acid; Male; Methy

1987
Serotonin as a facilitatory neurotransmitter in the anticonvulsant activity of methaqualone.
    Physiology & behavior, 1989, Volume: 46, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Anticonvulsants; Brain; Dose-Response Relationship, Drug; Fenclonine;

1989
Audiogenic seizures and brain serotonin after L-tryptophan and p-chlorophenylalanine.
    Experimental neurology, 1985, Volume: 90, Issue:3

    Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Brain Chemistry; Female; Fenclonine; Male; Mice;

1985
Participation of serotonergic mechanisms in the anticonvulsant effect of stress in mice treated with pentylenetetrazol.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1988, Volume: 21, Issue:2

    Topics: Animals; Cold Temperature; Fenclonine; Male; Methysergide; Mice; Mice, Inbred Strains; Pentylenetetr

1988
Prostaglandin D2 inhibits pentylenetetrazole-induced convulsions in rats by a serotonin-mediated mechanism.
    Pharmaceutical research, 1987, Volume: 4, Issue:5

    Topics: Animals; Dihydroxytryptamines; Dinoprost; Female; Fenclonine; Male; Metergoline; Pentylenetetrazole;

1987
Mechanism of p-chlorophenylalanine-mediated increase in seizure susceptibility: inhibition by cerebellar ablation.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 139, Issue:2

    Topics: Adrenergic Agents; Animals; Brain Chemistry; Cerebellum; Fenclonine; Male; Pentylenetetrazole; Pheny

1972
The role of biogenic amines in the reserpine-induced alteration of minimal electroshock seizure thresholds in the mouse.
    Neuropharmacology, 1973, Volume: 12, Issue:7

    Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain; Disulfiram; Dopamine; Drug Interactions; Elect

1973
Anticonvulsive effect of p-chlorophenylalanine in audiosensitive mice.
    Life sciences. Pt. 1: Physiology and pharmacology, 1971, Aug-01, Volume: 10, Issue:15

    Topics: Animals; Brain Chemistry; Fenclonine; Male; Mice; Phenylalanine; Seizures; Serotonin; Sound

1971
Seizure susceptibility after manipulation of brain serotonin.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 188, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood-Brain Barrier; Bra

1970
Reserpine-induced alterations in brain amines and their relationship to changes in the incidence of minimal electroshock seizures in mice.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 180, Issue:3

    Topics: Animals; Biogenic Amines; Brain; Brain Chemistry; Dopamine; Dopamine Antagonists; Drug Combinations;

1972
The role of brain serotonin in DDT-induced hyperpyrexia.
    Journal of neurochemistry, 1972, Volume: 19, Issue:4

    Topics: Animals; Brain; Brain Stem; DDT; Fenclonine; Fever; Fluorine; Hydroxyindoleacetic Acid; Male; Pargyl

1972
Reduced cataleptogenic effects of some neuroleptics in rats with lesioned midbrain raphe and treated with p-chlorophenylalanine.
    Brain research, 1972, Dec-24, Volume: 48

    Topics: Animals; Chlorpromazine; Corpus Striatum; Dopamine; Female; Fenclonine; Haloperidol; Medulla Oblonga

1972
Effects of some cholinergic, adrenergic and serotoninergic compounds, glutamic acid and GABA on hippocampal seizures.
    Pharmacology, 1973, Volume: 9, Issue:4

    Topics: Acetylcholine; Aminobutyrates; Animals; Atropine; Dibenzylchlorethamine; Female; Fenclonine; Glutama

1973
Role of brain 5-hydroxytryptamine in audiogenic seizure in the rat.
    Life sciences, 1973, Jul-01, Volume: 13, Issue:1

    Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Brain; Cold Temperature; Dopamine; Dose-Response

1973
Effects of 5-hydroxytryptophan, iproniazid and p-chlorophenylalanine on lidocaine seizure threshold of mice.
    European journal of pharmacology, 1974, Volume: 29, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Synergism; Fen

1974
Interaction of pentylenetetrazol and trimethadione on the metabolism of serotonin in brain and its relation to the anticonvulsant action of trimethadione.
    Neuropharmacology, 1974, Volume: 13, Issue:7

    Topics: 5-Hydroxytryptophan; Animals; Anticonvulsants; Brain; Brain Chemistry; Dose-Response Relationship, D

1974
Susceptibility to audiogenic stimuli induced by hyperbaric oxygenation and various neuroactive agents.
    Experimental neurology, 1971, Volume: 33, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Atropine; Brain; Dihydroxyphenylalanine; Fenclonine; Hyperbaric Oxygen

1971
The role of central monoamines in decapitation convulsions of mice.
    Neuropharmacology, 1971, Volume: 10, Issue:5

    Topics: Amines; Amphetamine; Animals; Brain; Dihydroxyphenylalanine; Dopamine; Fenclonine; Guanethidine; Mal

1971