dimethyl sulfoxide has been researched along with Seizures in 25 studies
Dimethyl Sulfoxide: A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during CRYOPRESERVATION. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
dimethyl sulfoxide : A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| " AFR/DMSO content was increased significantly in fresh hippocampus or plasma obtained during kainate-induced seizures of mice, reaching maximum levels at 90 min after intraperitoneal administration of 50 mg/kg kainic acid." | 7.76 | An electron spin resonance study for real-time detection of ascorbyl free radicals after addition of dimethyl sulfoxide in murine hippocampus or plasma during kainic acid-induced seizures. ( Hagiwara, S; Iwasaka, H; Koga, H; Matsumoto, S; Noguchi, T; Shingu, C; Yokoi, I, 2010) |
| "9% saline, n = 5), the EP groups (lithium-pilocarpine was used to induce epilepsy, and tissues were harvested at 6 and 24 h, every time point, n = 5), the EP + Compound C group (the specific inhibitor of PGC-1α, 15 mg/kg in 2% DMSO, n = 5), and the EP + DMSO group (0." | 4.31 | PGC-1α Affects Epileptic Seizures by Regulating Mitochondrial Fusion in Epileptic Rats. ( Li, D; Liu, X; Luo, Z; Qiu, X; Tai, Z; Tuo, J; Wang, J; Xu, Z; Yang, J; Zhang, F; Zhang, H; Zhang, L, 2023) |
| " AFR/DMSO content was increased significantly in fresh hippocampus or plasma obtained during kainate-induced seizures of mice, reaching maximum levels at 90 min after intraperitoneal administration of 50 mg/kg kainic acid." | 3.76 | An electron spin resonance study for real-time detection of ascorbyl free radicals after addition of dimethyl sulfoxide in murine hippocampus or plasma during kainic acid-induced seizures. ( Hagiwara, S; Iwasaka, H; Koga, H; Matsumoto, S; Noguchi, T; Shingu, C; Yokoi, I, 2010) |
| "Unfortunately, he also developed cardiac arrest and required intubation for ventilation after the seizure." | 1.48 | Dimethyl Sulfoxide-Induced Tonic-Clonic Seizure and Cardiac Arrest During Infusion of Autologous Peripheral Blood Stem Cells. ( Albayrak, M; Maral, S; Ozturk, HB; Pala, C; Sahin, O; Yildiz, A, 2018) |
| "Dimethyl sulfoxide (DMSO) has been widely used in the treatment of arthritis and certain inflammatory diseases, and is also considered an alternative remedy for cancer even if not supported by concrete evidence." | 1.32 | Massive intracranial hemorrhage associated with the ingestion of dimethyl sulfoxide. ( Karcioglu, O; Niyazi Ozucelik, D; Oray, D; Ozsarac, M; Topacoglu, H; Tuncok, Y, 2004) |
| "When tested against PTZ-induced convulsions, PEA protected against tonic convulsions and prolonged the latency between convulsive episodes." | 1.32 | Selective antiepileptic effects of N-palmitoylethanolamide, a putative endocannabinoid. ( Corcoran, ME; Saucier, DM; Sheerin, AH; Zhang, X, 2004) |
| "ALA-induced convulsions were not prevented by ascorbic acid, but were partially prevented by DMSO and completely prevented by ebselen." | 1.32 | Dimethyl sulfoxide and ebselen prevent convulsions induced by 5-aminolevulinic acid. ( Agostini, AN; Augusti, PR; Emanuelli, T; Mello, CF; Morimoto, A; Prauchner, CA; Unfer, TC; Zeni, G, 2004) |
| "Two types of motor seizures--minimal, clonic and major, generalized tonic-clonic--were elicited by a 100-mg/kg dose of metrazol (s." | 1.28 | Antimetrazol action of two potential anticonvulsants, CM 40907 and SR 41378, in immature rats. ( Mares, P; Stanková, L, 1992) |
| "MK-801, at all doses, reduced seizures in all groups (p less than or equal to 0." | 1.28 | Antagonism of cocaine, amphetamine, and methamphetamine toxicity. ( Albertson, TE; Derlet, RW; Rice, P, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (24.00) | 18.7374 |
| 1990's | 6 (24.00) | 18.2507 |
| 2000's | 6 (24.00) | 29.6817 |
| 2010's | 4 (16.00) | 24.3611 |
| 2020's | 3 (12.00) | 2.80 |
| Authors | Studies |
|---|---|
| Walters, JM | 1 |
| Kim, EC | 1 |
| Zhang, J | 1 |
| Jeong, HG | 1 |
| Bajaj, A | 1 |
| Baculis, BC | 1 |
| Tracy, GC | 1 |
| Ibrahim, B | 1 |
| Christian-Hinman, CA | 1 |
| Llano, DA | 1 |
| Huesmann, GR | 1 |
| Chung, HJ | 1 |
| Fang, Q | 1 |
| Zheng, S | 1 |
| Chen, Q | 1 |
| Chen, L | 1 |
| Yang, Y | 1 |
| Wang, Y | 1 |
| Zhang, H | 4 |
| Chen, J | 1 |
| Li, D | 3 |
| Zhang, L | 3 |
| Tuo, J | 3 |
| Zhang, F | 3 |
| Tai, Z | 3 |
| Liu, X | 3 |
| Qiu, X | 3 |
| Yang, J | 3 |
| Wang, J | 3 |
| Luo, Z | 3 |
| Xu, Z | 3 |
| Maral, S | 1 |
| Albayrak, M | 1 |
| Pala, C | 1 |
| Yildiz, A | 1 |
| Sahin, O | 1 |
| Ozturk, HB | 1 |
| Prigol, M | 1 |
| Schumacher, RF | 1 |
| WayneNogueira, C | 1 |
| Zeni, G | 2 |
| Piato, AL | 1 |
| Detanico, BC | 1 |
| Linck, VM | 1 |
| Herrmann, AP | 1 |
| Nunes, DS | 1 |
| Elisabetsky, E | 1 |
| Matsumoto, S | 1 |
| Shingu, C | 1 |
| Koga, H | 1 |
| Hagiwara, S | 1 |
| Iwasaka, H | 1 |
| Noguchi, T | 1 |
| Yokoi, I | 1 |
| Martín-Henao, GA | 1 |
| Resano, PM | 1 |
| Villegas, JM | 1 |
| Manero, PP | 1 |
| Sánchez, JM | 1 |
| Bosch, MP | 1 |
| Codins, AE | 1 |
| Bruguera, MS | 1 |
| Infante, LR | 1 |
| Oyarzabal, AP | 1 |
| Soldevila, RN | 1 |
| Caiz, DC | 1 |
| Bosch, LM | 1 |
| Barbeta, EC | 1 |
| Ronda, JR | 1 |
| Topacoglu, H | 1 |
| Karcioglu, O | 1 |
| Ozsarac, M | 1 |
| Oray, D | 1 |
| Niyazi Ozucelik, D | 1 |
| Tuncok, Y | 1 |
| Sheerin, AH | 1 |
| Zhang, X | 1 |
| Saucier, DM | 1 |
| Corcoran, ME | 1 |
| Prauchner, CA | 1 |
| Agostini, AN | 1 |
| Morimoto, A | 1 |
| Augusti, PR | 1 |
| Unfer, TC | 1 |
| Mello, CF | 1 |
| Emanuelli, T | 1 |
| Bauwens, D | 1 |
| Hantson, P | 1 |
| Laterre, PF | 1 |
| Michaux, L | 1 |
| Latinne, D | 1 |
| De Tourtchaninoff, M | 1 |
| Cosnard, G | 1 |
| Hernalsteen, D | 1 |
| Katz, L | 1 |
| Natoff, IL | 1 |
| Reiff, B | 1 |
| Golden, GT | 1 |
| Fariello, RG | 1 |
| Scriba, GK | 1 |
| Lambert, DM | 1 |
| Poupaert, JH | 1 |
| Bodjarian, N | 1 |
| Carpentier, P | 1 |
| Baubichon, D | 1 |
| Blanchet, G | 1 |
| Lallement, G | 1 |
| Mori, N | 1 |
| Morgant, G | 1 |
| Viossat, B | 1 |
| Daran, JC | 1 |
| Roch-Arveiller, M | 1 |
| Giroud, JP | 1 |
| Nguyen, HD | 1 |
| Sorenson, JR | 1 |
| Stanková, L | 1 |
| Mares, P | 1 |
| Derlet, RW | 1 |
| Albertson, TE | 1 |
| Rice, P | 1 |
| Kryzhanovskiĭ, GN | 1 |
| Shandra, AA | 1 |
| Makul'kin, RF | 1 |
| Godlevskiĭ, LS | 1 |
| Herman, ZS | 1 |
| Kästner, I | 1 |
| Braude, MC | 1 |
| Monroe, RR | 1 |
1 review available for dimethyl sulfoxide and Seizures
| Article | Year |
|---|---|
Roles of excitatory amino acids in expression of secondarily generalized limbic seizures: observations in the kindling model of epilepsy.
Topics: 2-Amino-5-phosphonovalerate; Animals; Aspartic Acid; Dimethyl Sulfoxide; Electric Stimulation; Gluta | 1993 |
24 other studies available for dimethyl sulfoxide and Seizures
| Article | Year |
|---|---|
Pharmacological inhibition of STriatal-Enriched protein tyrosine Phosphatase by TC-2153 reduces hippocampal excitability and seizure propensity.
Topics: Animals; Benzothiepins; Dimethyl Sulfoxide; Female; Hippocampus; Kainic Acid; Male; Mice; Mice, Inbr | 2022 |
The protective effect of inhibiting mitochondrial fission on the juvenile rat brain following PTZ kindling through inhibiting the BCL2L13/LC3 mitophagy pathway.
Topics: Animals; Brain Injuries; Caspase 3; Dimethyl Sulfoxide; Epilepsy; Hippocampus; Kindling, Neurologic; | 2023 |
PGC-1α Affects Epileptic Seizures by Regulating Mitochondrial Fusion in Epileptic Rats.
Topics: AMP-Activated Protein Kinases; Animals; Dimethyl Sulfoxide; Epilepsy; Lithium; Male; Mitochondrial D | 2023 |
PGC-1α Affects Epileptic Seizures by Regulating Mitochondrial Fusion in Epileptic Rats.
Topics: AMP-Activated Protein Kinases; Animals; Dimethyl Sulfoxide; Epilepsy; Lithium; Male; Mitochondrial D | 2023 |
PGC-1α Affects Epileptic Seizures by Regulating Mitochondrial Fusion in Epileptic Rats.
Topics: AMP-Activated Protein Kinases; Animals; Dimethyl Sulfoxide; Epilepsy; Lithium; Male; Mitochondrial D | 2023 |
PGC-1α Affects Epileptic Seizures by Regulating Mitochondrial Fusion in Epileptic Rats.
Topics: AMP-Activated Protein Kinases; Animals; Dimethyl Sulfoxide; Epilepsy; Lithium; Male; Mitochondrial D | 2023 |
Dimethyl Sulfoxide-Induced Tonic-Clonic Seizure and Cardiac Arrest During Infusion of Autologous Peripheral Blood Stem Cells.
Topics: Dimethyl Sulfoxide; Fatal Outcome; Heart Arrest; Humans; Male; Middle Aged; Peripheral Blood Stem Ce | 2018 |
Convulsant effect of diphenyl diselenide in rats and mice and its relationship to plasma levels.
Topics: Administration, Oral; Animals; Benzene Derivatives; Dimethyl Sulfoxide; Dose-Response Relationship, | 2009 |
Anti-stress effects of the "tonic"Ptychopetalum olacoides (Marapuama) in mice.
Topics: Animals; Anti-Anxiety Agents; Antioxidants; Anxiety; Blood Glucose; Dimethyl Sulfoxide; Hyperglycemi | 2010 |
An electron spin resonance study for real-time detection of ascorbyl free radicals after addition of dimethyl sulfoxide in murine hippocampus or plasma during kainic acid-induced seizures.
Topics: Animals; Ascorbic Acid; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Free Radicals; Hip | 2010 |
Adverse reactions during transfusion of thawed haematopoietic progenitor cells from apheresis are closely related to the number of granulocyte cells in the leukapheresis product.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cryopreservation; Cryoprotective Agents; Dimethyl | 2010 |
Massive intracranial hemorrhage associated with the ingestion of dimethyl sulfoxide.
Topics: Diagnosis, Differential; Dimethyl Sulfoxide; Fatal Outcome; Humans; Intracranial Hemorrhages; Male; | 2004 |
Selective antiepileptic effects of N-palmitoylethanolamide, a putative endocannabinoid.
Topics: Amides; Amygdala; Animals; Cannabinoid Receptor Modulators; Cannabinoids; Dimethyl Sulfoxide; Dose-R | 2004 |
Dimethyl sulfoxide and ebselen prevent convulsions induced by 5-aminolevulinic acid.
Topics: Aminolevulinic Acid; Animals; Azoles; Dimethyl Sulfoxide; Isoindoles; Male; Organoselenium Compounds | 2004 |
Recurrent seizure and sustained encephalopathy associated with dimethylsulfoxide-preserved stem cell infusion.
Topics: Cryopreservation; Dimethyl Sulfoxide; Fatal Outcome; Humans; Lymphoma, Large B-Cell, Diffuse; Male; | 2005 |
Perinatal asphyxia syndrome in a quarter horse foal.
Topics: Analgesics, Non-Narcotic; Animals; Anti-Bacterial Agents; Asphyxia; Blood Cell Count; Blood Chemical | 2006 |
The effect of dieldrin (HEOD) on chronaxie and convulsion thresholds in rats and mice.
Topics: Animals; Chronaxy; Dieldrin; Dimethyl Sulfoxide; In Vitro Techniques; Mice; Nervous System; Pentylen | 1967 |
Penicillin spikes in rats. Limitations of a simple model for the study of anticonvulsants.
Topics: Action Potentials; Animals; Anticonvulsants; Dimethyl Sulfoxide; Disease Models, Animal; Drug Evalua | 1984 |
Anticonvulsant activity of phenytoin-lipid conjugates, a new class of phenytoin prodrugs.
Topics: Administration, Oral; Animals; Anticonvulsants; Dimethyl Sulfoxide; Electroshock; Hydrolysis; In Vit | 1995 |
Involvement of non-muscarinic receptors in phosphoinositide signalling during soman-induced seizures.
Topics: Animals; Chlorpheniramine; Dimethyl Sulfoxide; Electroencephalography; Inositol 1,4,5-Trisphosphate; | 1995 |
Crystal structure of 180 degree K of bis-3, 5-diisopropylsalicylatobisdimethylsulfoxidozinc(II) and the inhibition of seizures and polymorphonuclear leukocyte chemiluminescence.
Topics: Animals; Anticonvulsants; Crystallography, X-Ray; Dimethyl Sulfoxide; Electroshock; Luminescent Meas | 1998 |
Antimetrazol action of two potential anticonvulsants, CM 40907 and SR 41378, in immature rats.
Topics: Animals; Anticonvulsants; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Male; Pentylenetetra | 1992 |
Antagonism of cocaine, amphetamine, and methamphetamine toxicity.
Topics: Amphetamine; Animals; Behavior, Animal; Cocaine; Diazepam; Dimethyl Sulfoxide; Dizocilpine Maleate; | 1990 |
[The hippocampus as the determinant structure generating epileptic activity during korazol kindling].
Topics: Animals; Behavior, Animal; Cerebral Cortex; Diazepam; Dimethyl Sulfoxide; Electroencephalography; Ep | 1985 |
Behavioural effects of dibutyryl cyclic 3',5' AMP, noradrenaline and cyclic 3',5' AMP in rats.
Topics: Animals; Behavior, Animal; Cerebral Ventricles; Cyclic AMP; Dimethyl Sulfoxide; Drug Interactions; I | 1973 |
[Attempts to trigger epileptic activity in the bulbus olfactorius in albino rats].
Topics: Animals; Cobalt; Dimethyl Sulfoxide; Electroencephalography; Male; Mescaline; Olfactory Bulb; Penici | 1974 |
Effects of dimethyl sulfoxide and alphaglucochloralose on pentylenetetrazol convulsive thresholds in mice.
Topics: Animals; Anticonvulsants; Ataxia; Central Nervous System; Chloralose; Dimethyl Sulfoxide; Drug Syner | 1967 |