ketorolac has been researched along with Seizures in 2 studies
Ketorolac: A pyrrolizine carboxylic acid derivative structurally related to INDOMETHACIN. It is an NSAID and is used principally for its analgesic activity. (From Martindale The Extra Pharmacopoeia, 31st ed)
ketorolac : A racemate comprising equimolar amounts of (R)-(+)- and (S)-(-)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid. While only the (S)-(-) enantiomer is a COX1 and COX2 inhibitor, the (R)-(+) enantiomer exhibits potent analgesic activity. A non-steroidal anti-inflammatory drug, ketorolac is mainly used (generally as the tromethamine salt) for its potent analgesic properties in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It was withdrawn from the market in many countries in 1993 following association with haemorrhage and renal failure.
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid : A member of the class of pyrrolizines that is 2,3-dihydro-1H-pyrrolizine which is substituted at positions 1 and 5 by carboxy and benzoyl groups, respectively.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report three cases of meperidine-related seizures when meperidine was administered via patient-controlled analgesia pump (PCAP) and to review literature related to meperidine-associated seizures." | 8.78 | Meperidine-related seizures associated with patient-controlled analgesia pumps. ( Hagmeyer, KO; Mauro, LS; Mauro, VF, 1993) |
| "To report three cases of meperidine-related seizures when meperidine was administered via patient-controlled analgesia pump (PCAP) and to review literature related to meperidine-associated seizures." | 4.78 | Meperidine-related seizures associated with patient-controlled analgesia pumps. ( Hagmeyer, KO; Mauro, LS; Mauro, VF, 1993) |
| "The initiation time of myoclonic seizures (ITMS), the initiation time of tonic-clonic seizures (ITTS), seizure duration (SD), and mortality rate (MR) were measured for 30 min." | 1.91 | Effects of Intracerebroventricular Injection of the Steroidal and Non-Steroidal Anti-Inflammatory Drugs on the Seizures during the Estrous Cycle in Rat. ( Fazlelahi, Z; Kaboutari, J; Panahi, N; Zendehdel, M, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fazlelahi, Z | 1 |
| Kaboutari, J | 1 |
| Zendehdel, M | 1 |
| Panahi, N | 1 |
| Hagmeyer, KO | 1 |
| Mauro, LS | 1 |
| Mauro, VF | 1 |
1 review available for ketorolac and Seizures
| Article | Year |
|---|---|
Meperidine-related seizures associated with patient-controlled analgesia pumps.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Epilepsy, Tonic-Clonic; Female; Humans; Ketorolac; | 1993 |
1 other study available for ketorolac and Seizures
| Article | Year |
|---|---|
Effects of Intracerebroventricular Injection of the Steroidal and Non-Steroidal Anti-Inflammatory Drugs on the Seizures during the Estrous Cycle in Rat.
Topics: Animals; Anti-Inflammatory Agents; Estrous Cycle; Female; Inflammation; Ketorolac; Methylprednisolon | 2023 |