nitrites has been researched along with Seizures in 26 studies
Nitrites: Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M=metal) are all insoluble, except the alkali nitrites. The organic nitrites may be isomeric, but not identical with the corresponding nitro compounds. (Grant & Hackh's Chemical Dictionary, 5th ed)
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study was envisaged to evaluate the ameliorative effect of Curcumin on depression like behavior and cognitive impairment observed in pentylenetetrazole kindled animals." | 7.79 | Ameliorative effect of Curcumin on seizure severity, depression like behavior, learning and memory deficit in post-pentylenetetrazole-kindled mice. ( Choudhary, KM; Goel, RK; Mishra, A; Poroikov, VV, 2013) |
| "This study was proposed to investigate the potential protective effect of alpha-lipoic acid (α-LA) against potassium cyanide (KCN)-induced seizures and lethality in mice." | 7.77 | Alpha-lipoic acid protects against potassium cyanide-induced seizures and mortality. ( Abdel Moneim, WM; Abdel-Hady, RH; Abdel-Zaher, AO; Salim, SY, 2011) |
| " The objective of the present study was to evaluate the neuroprotective effects of alpha-tocopherol in rats against oxidative stress caused by pilocarpine-induced seizures." | 7.77 | Oxidative stress in rat striatum after pilocarpine-induced seizures is diminished by alpha-tocopherol. ( Costa, JP; de Freitas, RM; de Souza, GF; dos Santos, PS; Feng, D; Saldanha, GB; Tomé, Ada R, 2011) |
| " We studied the buspirone effects on oxidative stress in rat hippocampus after seizures and status epilepticus (SE) induced by pilocarpine." | 7.76 | Oxidative stress in rat hippocampus caused by pilocarpine-induced seizures is reversed by buspirone. ( de Freitas, RL; de Freitas, RM; de Souza, GF; Saldanha, GB; Santos, IM; Tomé, Ada R, 2010) |
| "It has been suggested that pilocarpine-induced seizures is mediated by increases in oxidative stress." | 7.75 | The evaluation of effects of lipoic acid on the lipid peroxidation, nitrite formation and antioxidant enzymes in the hippocampus of rats after pilocarpine-induced seizures. ( Freitas, RM, 2009) |
| " Using the epilepsy model obtained by systemic administration of pilocarpine in rats, we investigated the lipid peroxidation, nitrite content, superoxide dismutase (SOD) and catalase activities in the hippocampus of rats during chronic period." | 7.75 | Investigation of oxidative stress involvement in hippocampus in epilepsy model induced by pilocarpine. ( Freitas, RM, 2009) |
| " Levetiracetam (LEV) is a new antiepileptic agent with broad-spectrum effects on seizures and animal models of epilepsy." | 7.74 | Effects of levetiracetam in lipid peroxidation level, nitrite-nitrate formation and antioxidant enzymatic activity in mice brain after pilocarpine-induced seizures. ( Aguiar, LM; Almeida, JP; Fonseca, FN; Fonteles, MM; Freitas, RM; Júnior, HV; Nascimento, VS; Oliveira, AA; Sousa, FC; Viana, GS, 2007) |
| "To clarify the role of nitric oxide (NO) in the pathogenesis of seizures in susceptible EL mice, we investigated effects of three drugs potentially related to NO production, MK-801, dantrolene, and FK506, on convulsive seizures and brain NO metabolites (NOx)." | 7.71 | Effects of MK-801, dantrolene, and FK506 on convulsive seizures and brain nitric oxide production in seizure-susceptible EL mice. ( Akasaki, Y; Hashiguchi, W; Nagatomo, I; Takigawa, M; Tominaga, M; Uchida, M, 2001) |
| "Seizures were induced by pentylenetetrazol and maximal electroshock." | 5.72 | Opioidergic and nitrergic systems mediate the anticonvulsant effect of mefloquine and chloroquine on seizures induced by pentylenetetrazol and maximal electroshock in mice. ( Boroujeni, SS; Dehpour, AR; Jafari, RM; Karimi, E; Maleki, A; Mohammadi, P; Sabzevari, O; Shafaroodi, H; Solaimanian, S, 2022) |
| " This study was envisaged to evaluate the ameliorative effect of Curcumin on depression like behavior and cognitive impairment observed in pentylenetetrazole kindled animals." | 3.79 | Ameliorative effect of Curcumin on seizure severity, depression like behavior, learning and memory deficit in post-pentylenetetrazole-kindled mice. ( Choudhary, KM; Goel, RK; Mishra, A; Poroikov, VV, 2013) |
| "This study was proposed to investigate the potential protective effect of alpha-lipoic acid (α-LA) against potassium cyanide (KCN)-induced seizures and lethality in mice." | 3.77 | Alpha-lipoic acid protects against potassium cyanide-induced seizures and mortality. ( Abdel Moneim, WM; Abdel-Hady, RH; Abdel-Zaher, AO; Salim, SY, 2011) |
| " The objective of the present study was to evaluate the neuroprotective effects of alpha-tocopherol in rats against oxidative stress caused by pilocarpine-induced seizures." | 3.77 | Oxidative stress in rat striatum after pilocarpine-induced seizures is diminished by alpha-tocopherol. ( Costa, JP; de Freitas, RM; de Souza, GF; dos Santos, PS; Feng, D; Saldanha, GB; Tomé, Ada R, 2011) |
| " We studied the buspirone effects on oxidative stress in rat hippocampus after seizures and status epilepticus (SE) induced by pilocarpine." | 3.76 | Oxidative stress in rat hippocampus caused by pilocarpine-induced seizures is reversed by buspirone. ( de Freitas, RL; de Freitas, RM; de Souza, GF; Saldanha, GB; Santos, IM; Tomé, Ada R, 2010) |
| "It has been suggested that pilocarpine-induced seizures is mediated by increases in oxidative stress." | 3.75 | The evaluation of effects of lipoic acid on the lipid peroxidation, nitrite formation and antioxidant enzymes in the hippocampus of rats after pilocarpine-induced seizures. ( Freitas, RM, 2009) |
| " Using the epilepsy model obtained by systemic administration of pilocarpine in rats, we investigated the lipid peroxidation, nitrite content, superoxide dismutase (SOD) and catalase activities in the hippocampus of rats during chronic period." | 3.75 | Investigation of oxidative stress involvement in hippocampus in epilepsy model induced by pilocarpine. ( Freitas, RM, 2009) |
| " Levetiracetam (LEV) is a new antiepileptic agent with broad-spectrum effects on seizures and animal models of epilepsy." | 3.74 | Effects of levetiracetam in lipid peroxidation level, nitrite-nitrate formation and antioxidant enzymatic activity in mice brain after pilocarpine-induced seizures. ( Aguiar, LM; Almeida, JP; Fonseca, FN; Fonteles, MM; Freitas, RM; Júnior, HV; Nascimento, VS; Oliveira, AA; Sousa, FC; Viana, GS, 2007) |
| "To clarify the role of nitric oxide (NO) in the pathogenesis of seizures in susceptible EL mice, we investigated effects of three drugs potentially related to NO production, MK-801, dantrolene, and FK506, on convulsive seizures and brain NO metabolites (NOx)." | 3.71 | Effects of MK-801, dantrolene, and FK506 on convulsive seizures and brain nitric oxide production in seizure-susceptible EL mice. ( Akasaki, Y; Hashiguchi, W; Nagatomo, I; Takigawa, M; Tominaga, M; Uchida, M, 2001) |
| "Seizures were induced by pentylenetetrazol and maximal electroshock." | 1.72 | Opioidergic and nitrergic systems mediate the anticonvulsant effect of mefloquine and chloroquine on seizures induced by pentylenetetrazol and maximal electroshock in mice. ( Boroujeni, SS; Dehpour, AR; Jafari, RM; Karimi, E; Maleki, A; Mohammadi, P; Sabzevari, O; Shafaroodi, H; Solaimanian, S, 2022) |
| "Chloroquine has long been used for the treatment of malaria and rheumatological disorders." | 1.43 | Possible involvement of nitrergic and opioidergic systems in the modulatory effect of acute chloroquine treatment on pentylenetetrazol induced convulsions in mice. ( Abkhoo, A; Amiri, S; Boojar, MM; Dehpour, AR; Delazar, S; Hassanipour, M; Ostadhadi, S; Rahimi, N; Shirzadian, A, 2016) |
| "In the pilocarpine-induced seizure model, all dosages of agomelatine or melatonin showed a significant decrease in TBARS levels and nitrite content in all brain areas when compared to controls." | 1.39 | Effects of agomelatine on oxidative stress in the brain of mice after chemically induced seizures. ( Aguiar, CC; Almeida, AB; Araújo, PV; Chaves, EM; de Barros Viana, GS; do Vale, OC; Leal, LK; Macêdo, DS; Vasconcelos, GS; Vasconcelos, SM, 2013) |
| "Kainic acid is an endogenous excitotoxin acting on glutamate receptors, that leads to neurotoxic damage resembling the alterations observed in some neurological disorders." | 1.32 | 7-nitroindazole reduces nitrite concentration in rat brain after intrahippocampal kainate-induced seizure. ( Jovanovic, M; Radenovic, L; Selakovic, V; Vasiljevic, I, 2003) |
| "Seizures were induced by single administration of PTZ, which was associated with an increase in levels of NO metabolites (NOx) in the hippocampus." | 1.31 | Involvement of nitric oxide in pentylenetetrazole-induced kindling in rats. ( Han, D; Nabeshima, T; Nawa, H; Senzaki, K; Xiong, H; Yamada, K, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (15.38) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (34.62) | 29.6817 |
| 2010's | 12 (46.15) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Boroujeni, SS | 1 |
| Solaimanian, S | 1 |
| Jafari, RM | 1 |
| Sabzevari, O | 1 |
| Shafaroodi, H | 1 |
| Maleki, A | 1 |
| Mohammadi, P | 1 |
| Karimi, E | 1 |
| Dehpour, AR | 3 |
| Amini-Khoei, H | 1 |
| Kordjazy, N | 1 |
| Haj-Mirzaian, A | 2 |
| Amiri, S | 2 |
| Shirzadian, A | 2 |
| Hasanvand, A | 1 |
| Balali-Dehkordi, S | 1 |
| Hassanipour, M | 2 |
| Felipe, CFB | 1 |
| Albuquerque, AMS | 1 |
| de Pontes, JLX | 1 |
| de Melo, JÍV | 1 |
| Rodrigues, TCML | 1 |
| de Sousa, AMP | 1 |
| Monteiro, ÁB | 1 |
| Ribeiro, AEDS | 1 |
| Lopes, JP | 1 |
| de Menezes, IRA | 1 |
| de Almeida, RN | 1 |
| Choudhary, KM | 1 |
| Mishra, A | 1 |
| Poroikov, VV | 1 |
| Goel, RK | 1 |
| Aguiar, CC | 1 |
| Almeida, AB | 1 |
| Araújo, PV | 1 |
| Vasconcelos, GS | 1 |
| Chaves, EM | 1 |
| do Vale, OC | 1 |
| Macêdo, DS | 1 |
| Leal, LK | 2 |
| de Barros Viana, GS | 2 |
| Vasconcelos, SM | 1 |
| Bhardwaj, M | 1 |
| Kumar, A | 1 |
| Boojar, MM | 1 |
| Abkhoo, A | 2 |
| Delazar, S | 1 |
| Rahimi, N | 1 |
| Ostadhadi, S | 1 |
| Freitas, RM | 3 |
| Morichi, S | 1 |
| Kawashima, H | 2 |
| Ioi, H | 1 |
| Ushio, M | 1 |
| Yamanaka, G | 1 |
| Kashiwagi, Y | 2 |
| Takekuma, K | 2 |
| Hoshika, A | 2 |
| Watanabe, Y | 2 |
| de Freitas, RL | 1 |
| Santos, IM | 1 |
| de Souza, GF | 2 |
| Tomé, Ada R | 2 |
| Saldanha, GB | 2 |
| de Freitas, RM | 2 |
| Abdel-Zaher, AO | 1 |
| Abdel-Hady, RH | 1 |
| Abdel Moneim, WM | 1 |
| Salim, SY | 1 |
| Bennet, L | 1 |
| Cowie, RV | 1 |
| Stone, PR | 1 |
| Barrett, R | 1 |
| Naylor, AS | 1 |
| Blood, AB | 1 |
| Gunn, AJ | 1 |
| Nogueira, CR | 1 |
| Damasceno, FM | 1 |
| de Aquino-Neto, MR | 1 |
| de Andrade, GM | 2 |
| Fontenele, JB | 1 |
| de Medeiros, TA | 1 |
| Viana, GS | 2 |
| dos Santos, PS | 1 |
| Costa, JP | 1 |
| Feng, D | 1 |
| da Cruz, GM | 1 |
| Felipe, CF | 1 |
| Scorza, FA | 1 |
| da Costa, MA | 1 |
| Tavares, AF | 1 |
| Menezes, ML | 1 |
| Brito, GA | 1 |
| da Graça Naffah-Mazzacoratti, M | 1 |
| Cavalheiro, EA | 1 |
| Radenovic, L | 1 |
| Vasiljevic, I | 1 |
| Selakovic, V | 1 |
| Jovanovic, M | 1 |
| SLAVKOVIC, J | 1 |
| DIMITROV, A | 1 |
| VUKOTIC, D | 1 |
| KENTERA, D | 1 |
| KOVACEVIC, M | 1 |
| HIRSCH, FG | 1 |
| Inage, Y | 1 |
| Ogihara, M | 1 |
| Mori, T | 1 |
| Oliveira, AA | 1 |
| Almeida, JP | 1 |
| Nascimento, VS | 1 |
| Aguiar, LM | 1 |
| Júnior, HV | 1 |
| Fonseca, FN | 1 |
| Sousa, FC | 1 |
| Fonteles, MM | 1 |
| Han, D | 1 |
| Yamada, K | 1 |
| Senzaki, K | 1 |
| Xiong, H | 1 |
| Nawa, H | 1 |
| Nabeshima, T | 1 |
| Nagatomo, I | 2 |
| Akasaki, Y | 2 |
| Uchida, M | 2 |
| Tominaga, M | 2 |
| Hashiguchi, W | 2 |
| Kuchiiwa, S | 1 |
| Nakagawa, S | 1 |
| Takigawa, M | 2 |
| Baumel, I | 1 |
| Pitterman, A | 1 |
| Defeo, JJ | 1 |
| Lal, H | 1 |
| Yoshikawa, H | 1 |
26 other studies available for nitrites and Seizures
| Article | Year |
|---|---|
Opioidergic and nitrergic systems mediate the anticonvulsant effect of mefloquine and chloroquine on seizures induced by pentylenetetrazol and maximal electroshock in mice.
Topics: Animals; Anticonvulsants; Chloroquine; Disease Models, Animal; Electroshock; Mefloquine; Mice; Naltr | 2022 |
Anticonvulsant effect of minocycline on pentylenetetrazole-induced seizure in mice: involvement of nitric oxide and N-methyl-d-aspartate receptor.
Topics: Animals; Anticonvulsants; Arginine; Enzyme Inhibitors; Hippocampus; Male; Mice; Minocycline; Nitric | 2018 |
Comparative study of alpha- and beta-pinene effect on PTZ-induced convulsions in mice.
Topics: Animals; Anticonvulsants; Bicyclic Monoterpenes; Brain; Bridged Bicyclo Compounds; Disease Models, A | 2019 |
Ameliorative effect of Curcumin on seizure severity, depression like behavior, learning and memory deficit in post-pentylenetetrazole-kindled mice.
Topics: Acetylcholinesterase; Animals; Anticonvulsants; Behavior, Animal; Brain; Convulsants; Curcumin; Depr | 2013 |
Effects of agomelatine on oxidative stress in the brain of mice after chemically induced seizures.
Topics: Acetamides; Animals; Brain; Catalase; Female; Lipid Peroxidation; Mice; Nitrites; Oxidative Stress; | 2013 |
Neuroprotective Effect of Lycopene Against PTZ-induced Kindling Seizures in Mice: Possible Behavioural, Biochemical and Mitochondrial Dysfunction.
Topics: Animals; Antioxidants; Behavior, Animal; Brain; Carotenoids; Catalase; Dose-Response Relationship, D | 2016 |
Possible involvement of nitrergic and opioidergic systems in the modulatory effect of acute chloroquine treatment on pentylenetetrazol induced convulsions in mice.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Anticonvulsants; Arginine; Chloroquine; Disease M | 2016 |
The evaluation of effects of lipoic acid on the lipid peroxidation, nitrite formation and antioxidant enzymes in the hippocampus of rats after pilocarpine-induced seizures.
Topics: Animals; Antioxidants; Catalase; Hippocampus; Lipid Peroxidation; Muscarinic Agonists; Neuroprotecti | 2009 |
Investigation of oxidative stress involvement in hippocampus in epilepsy model induced by pilocarpine.
Topics: Animals; Catalase; Chronic Disease; Epilepsy; Hippocampus; Lipid Peroxidation; Male; Nitrites; Oxida | 2009 |
Cerebrospinal fluid NOx (nitrite/nitrate) in RSV-infected children with CNS symptoms.
Topics: Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Muscle Rigidity; Nitrates; Nitric O | 2009 |
Oxidative stress in rat hippocampus caused by pilocarpine-induced seizures is reversed by buspirone.
Topics: Animals; Anticonvulsants; Buspirone; Catalase; Hippocampus; Lipid Peroxidation; Male; Nitrites; Oxid | 2010 |
Alpha-lipoic acid protects against potassium cyanide-induced seizures and mortality.
Topics: Animals; Antioxidants; Brain; Dose-Response Relationship, Drug; Glutamic Acid; Glutathione; Glutathi | 2011 |
The neural and vascular effects of killed Su-Streptococcus pyogenes (OK-432) in preterm fetal sheep.
Topics: Animals; Blood Pressure; Brain; Cardiovascular System; Cerebral Infarction; Electroencephalography; | 2010 |
Doxycycline protects against pilocarpine-induced convulsions in rats, through its antioxidant effect and modulation of brain amino acids.
Topics: Amino Acids; Animals; Antioxidants; Brain; Doxycycline; Free Radical Scavengers; Lipid Peroxidation; | 2011 |
Oxidative stress in rat striatum after pilocarpine-induced seizures is diminished by alpha-tocopherol.
Topics: alpha-Tocopherol; Animals; Behavior, Animal; Catalase; Lipid Peroxidation; Male; Neostriatum; Nitrit | 2011 |
Piperine decreases pilocarpine-induced convulsions by GABAergic mechanisms.
Topics: Alkaloids; Amino Acids; Animals; Anticonvulsants; Antioxidants; Atropine; Benzodioxoles; Biogenic Mo | 2013 |
7-nitroindazole reduces nitrite concentration in rat brain after intrahippocampal kainate-induced seizure.
Topics: Animals; Anticonvulsants; Brain; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Hippocampus; Ind | 2003 |
[Prolonged nitroglycerin utilization in prophylaxis of seizures of angina pectoris].
Topics: Angina Pectoris; Humans; Nitrites; Nitroglycerin; Seizures | 1957 |
CYANIDE POISONING.
Topics: Administration, Intravenous; Cyanides; Emetics; Humans; Infusions, Parenteral; Injections; Injection | 1964 |
Serum and cerebrospinal fluid nitrite/nitrate levels in patients with rotavirus gastroenteritis induced convulsion.
Topics: Child, Preschool; Chromatography, High Pressure Liquid; Female; Gastroenteritis; Humans; Immunoenzym | 2004 |
Effects of levetiracetam in lipid peroxidation level, nitrite-nitrate formation and antioxidant enzymatic activity in mice brain after pilocarpine-induced seizures.
Topics: Animals; Anticonvulsants; Antioxidants; Brain; Catalase; Glutathione; Levetiracetam; Lipid Peroxidat | 2007 |
Involvement of nitric oxide in pentylenetetrazole-induced kindling in rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Convulsants; Hippocampus; Kindling, Neurologic; Male; Ne | 2000 |
Age-related alterations of nitric oxide production in the brains of seizure-susceptible EL mice.
Topics: Aging; Animals; Body Weight; Brain; Cell Count; Cerebral Cortex; Corpus Striatum; Hippocampus; Mice; | 2000 |
Effects of MK-801, dantrolene, and FK506 on convulsive seizures and brain nitric oxide production in seizure-susceptible EL mice.
Topics: Animals; Brain; Brain Chemistry; Calcineurin; Calcium; Dantrolene; Disease Models, Animal; Dizocilpi | 2001 |
Effect of hypobaric hypoxia and sodium nitrite on convulsions due to intracerebral semicarbazide.
Topics: Animals; Anticonvulsants; Drug Antagonism; Hypoxia; Kinetics; Male; Mice; Nitrites; Seizures; Semica | 1970 |
[Toxicity of nitrile compounds. 1. Aliphatic nitriles].
Topics: Animals; Female; Mice; Nitriles; Nitrites; Seizures | 1968 |