niacin has been researched along with Seizures in 30 studies
Niacin: A water-soluble vitamin of the B complex occurring in various animal and plant tissues. It is required by the body for the formation of coenzymes NAD and NADP. It has PELLAGRA-curative, vasodilating, and antilipemic properties.
vitamin B3 : Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms).
nicotinic acid : A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pellagra is caused by deficiency of niacin or its precursor tryptophan." | 7.80 | Phenobarbital-induced pellagra resulted in death. ( Aydin, F; Cengiz, N; Onar, MK; Pancar Yuksel, E; Sen, N; Sen, S; Senturk, N, 2014) |
| " The evaluation of the side effects present shortly after dosing in the rotarod test has revealed neurotoxicity of Nic-BZA with experimentally determined TD50 value of 188." | 5.43 | Protective action of nicotinic acid benzylamide in a variety of chemically-induced seizures in mice. ( Paruszewski, R; Świąder, K; Świąder, MJ; Turski, WA; Łuszczki, JJ, 2016) |
| "In patients with epilepsy, there was insufficient intake of water, fiber, potassium, magnesium and some vitamins (C, E, B12, folate and niacin); suboptimal intake of calories, zinc, calcium, and some vitamins (A, B1 and B6); optimal intake of total fats; and over-intake of proteins, carbohydrates, phosphorus, iron, sodium, and vitamins D and B2." | 4.12 | Nutritional intake and its impact on patients with epilepsy: an analytical cross-sectional study. ( Abd El-Maoula, LM; El-Kholy, T; El-Sawy, E; Ibrahim El-Desoky, O; Ismail, RS; Kishk, NA; Rizk, HI; Shaheen, S, 2022) |
| "Pellagra is caused by deficiency of niacin or its precursor tryptophan." | 3.80 | Phenobarbital-induced pellagra resulted in death. ( Aydin, F; Cengiz, N; Onar, MK; Pancar Yuksel, E; Sen, N; Sen, S; Senturk, N, 2014) |
| " The evaluation of the side effects present shortly after dosing in the rotarod test has revealed neurotoxicity of Nic-BZA with experimentally determined TD50 value of 188." | 1.43 | Protective action of nicotinic acid benzylamide in a variety of chemically-induced seizures in mice. ( Paruszewski, R; Świąder, K; Świąder, MJ; Turski, WA; Łuszczki, JJ, 2016) |
| " The evaluation of time-course and dose-response relationships for iso-Nic-BZA provided evidence that the compound produced the peak to maximum antielectroshock action and acute adverse effects at 5min after its systemic (i." | 1.34 | Characterization of the anticonvulsant profile of isonicotinic acid benzylamide in various experimental seizure models in mice. ( Czuczwar, SJ; Luszczki, JJ; Paruszewski, R; Swiader, K; Swiader, MJ; Turski, WA, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (80.00) | 18.7374 |
| 1990's | 1 (3.33) | 18.2507 |
| 2000's | 1 (3.33) | 29.6817 |
| 2010's | 3 (10.00) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ismail, RS | 1 |
| Kishk, NA | 1 |
| Rizk, HI | 1 |
| El-Kholy, T | 1 |
| Abd El-Maoula, LM | 1 |
| Ibrahim El-Desoky, O | 1 |
| Shaheen, S | 1 |
| El-Sawy, E | 1 |
| Horne, DB | 1 |
| Biswas, K | 1 |
| Brown, J | 1 |
| Bartberger, MD | 1 |
| Clarine, J | 1 |
| Davis, CD | 1 |
| Gore, VK | 1 |
| Harried, S | 1 |
| Horner, M | 1 |
| Kaller, MR | 1 |
| Lehto, SG | 1 |
| Liu, Q | 1 |
| Ma, VV | 1 |
| Monenschein, H | 1 |
| Nguyen, TT | 1 |
| Yuan, CC | 1 |
| Youngblood, BD | 1 |
| Zhang, M | 1 |
| Zhong, W | 1 |
| Allen, JR | 1 |
| Chen, JJ | 1 |
| Gavva, NR | 1 |
| Pancar Yuksel, E | 1 |
| Sen, S | 1 |
| Aydin, F | 1 |
| Senturk, N | 1 |
| Sen, N | 1 |
| Cengiz, N | 1 |
| Onar, MK | 1 |
| Świąder, MJ | 2 |
| Łuszczki, JJ | 1 |
| Paruszewski, R | 2 |
| Świąder, K | 2 |
| Turski, WA | 2 |
| REILLY, RH | 1 |
| KILLAM, KF | 1 |
| JENNEY, EH | 1 |
| MARSHALL, WH | 1 |
| TAUSIG, T | 1 |
| APTER, NS | 1 |
| PFEIFFER, CC | 1 |
| COGNI, G | 1 |
| MIHICH, E | 1 |
| CEDRANGOLO, F | 3 |
| GIOIA, A | 3 |
| BAGNULO, R | 3 |
| PERITI, P | 4 |
| BUFFONI NARDINI, F | 2 |
| COSTA, E | 2 |
| CAMBA, R | 1 |
| MURTAS, L | 1 |
| RUSSO, A | 1 |
| MARINO, M | 1 |
| FERRARI, W | 1 |
| MANCINI, MA | 1 |
| KLINGHARDT, GW | 1 |
| RADENBACH, KL | 1 |
| MROWKA, S | 1 |
| PORCINO, F | 1 |
| PLEASURE, H | 1 |
| LUKAVSKY, J | 1 |
| PETROVICKY, O | 1 |
| KATZ, S | 1 |
| GIMBLE, A | 1 |
| MCCORMICK, G | 1 |
| PRESCOTT, B | 1 |
| LIVINGSTON, S | 1 |
| PETERSEN, D | 1 |
| PECK, JL | 1 |
| PISANTY, J | 1 |
| BERGER, P | 1 |
| NIAUSSAT, MM | 1 |
| SPAZIANTE, G | 1 |
| FRATELLO, U | 1 |
| Luszczki, JJ | 1 |
| Czuczwar, SJ | 1 |
| Connick, JH | 1 |
| Heywood, GC | 1 |
| Sills, GJ | 1 |
| Thompson, GG | 1 |
| Brodie, MJ | 1 |
| Stone, TW | 1 |
| Vezzani, A | 1 |
| Ungerstedt, U | 1 |
| French, ED | 1 |
| Schwarcz, R | 1 |
30 other studies available for niacin and Seizures
| Article | Year |
|---|---|
Nutritional intake and its impact on patients with epilepsy: an analytical cross-sectional study.
Topics: Calcium; Cross-Sectional Studies; Diet; Dietary Carbohydrates; Dietary Fats; Eating; Energy Intake; | 2022 |
Discovery of TRPM8 Antagonist ( S)-6-(((3-Fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)carbamoyl)nicotinic Acid (AMG 333), a Clinical Candidate for the Treatment of Migraine.
Topics: Animals; Anticonvulsants; Calcium Channel Agonists; Drug Discovery; Humans; Male; Microsomes, Liver; | 2018 |
Phenobarbital-induced pellagra resulted in death.
Topics: Adult; Anticonvulsants; Dermatitis; Fatal Outcome; Female; Humans; Niacin; Pellagra; Phenobarbital; | 2014 |
Protective action of nicotinic acid benzylamide in a variety of chemically-induced seizures in mice.
Topics: Animals; Anticonvulsants; Benzyl Compounds; Disease Models, Animal; Male; Memory Disorders; Memory, | 2016 |
Convulsant effects of isoniazid.
Topics: Convulsants; Convulsive Therapy; Humans; Isoniazid; Niacin; Nicotinic Acids; Seizures | 1953 |
[Explication of antagonistic action of certain drugs toward preparations of isonicotinic acid hydrazide group producing convulsions].
Topics: Hostility; Hypnotics and Sedatives; Isomerism; Isoniazid; Niacin; Nicotinic Acids; Seizures | 1953 |
[Decreased toxicity of isonicotinic acid hydrazide in association with glutamic acid].
Topics: Glutamates; Glutamic Acid; Isomerism; Isoniazid; Niacin; Nicotinic Acids; Seizures | 1953 |
[Decreased toxicity of isonicotinic acid hydrazide in association with glutamic acid].
Topics: Glutamates; Glutamic Acid; Isomerism; Isoniazid; Niacin; Nicotinic Acids; Seizures | 1953 |
[Decreased toxicity of isonicotinic acid hydrazide in association with glutamic acid].
Topics: Glutamates; Glutamic Acid; Isomerism; Isoniazid; Niacin; Nicotinic Acids; Seizures | 1953 |
[Isoniazid concentration in the cerebrospinal fluid of the ape and dog after intravenous administration, and relation to its convulsant effect].
Topics: Administration, Intravenous; Animals; Convulsants; Dogs; Isomerism; Isoniazid; Niacin; Nicotinic Aci | 1953 |
[Latency period of the sensitivity to the convulsive effect of isoniazid in the dog and ape after intravenous administration].
Topics: Administration, Intravenous; Animals; Dogs; Isomerism; Isoniazid; Niacin; Nicotinic Acids; Seizures | 1953 |
[Importance of the kidneys for the convulsant action of isonicotinic acid hydrazid].
Topics: Convulsants; Isomerism; Isonicotinic Acids; Kidney; Niacin; Nicotinic Acids; Seizures | 1953 |
[Nicotinamide in experimental asthmatic seizure].
Topics: Asthma; Niacin; Niacinamide; Nicotinic Acids; Seizures | 1952 |
[Mechanism of convulsive action of isonicotinic acid hydrazide].
Topics: Isomerism; Isoniazid; Niacin; Nicotinic Acids; Seizures | 1953 |
[Acute toxicity of isoniazid after intraspinal administration in monkey and in dog].
Topics: Animals; Dogs; Haplorhini; Isomerism; Isoniazid; Niacin; Nicotinic Acids; Seizures | 1953 |
[Experimental and clinical study of acute toxicology of isonicotinic acid hydrazide].
Topics: Barbiturates; Humans; Isoniazid; Niacin; Nicotinic Acids; Seizures | 1954 |
[Neurological complications of isoniazid therapy of tuberculosis].
Topics: Isoniazid; Nervous System; Neuritis; Niacin; Nicotinic Acids; Seizures; Tuberculosis | 1954 |
[Antagonistic effect of Indian hemp on toxic-convulsant syndrome due to isonicotinic acid hydrazide].
Topics: Apocynum; Cannabis; Convulsants; Hibiscus; Hostility; Isoniazid; Niacin; Nicotinic Acids; Seizures | 1954 |
Psychiatric and neurological side-effects of isoniazid and iproniazid.
Topics: Disease; Iproniazid; Isoniazid; Mental Disorders; Niacin; Nicotinic Acids; Psychotic Disorders; Seiz | 1954 |
[Two cases of toxic manifestations in the treatment of pulmonary tuberculosis with isonicotinic acid hydrazide].
Topics: Isoniazid; Kidney; Niacin; Nicotinic Acids; Seizures; Tuberculosis; Tuberculosis, Pulmonary | 1954 |
Glycine and sodium glucuronate in the management of convulsions due to hydrazides.
Topics: Anti-Bacterial Agents; Disease Management; Glucuronates; Glucuronic Acid; Glycine; Humans; Niacin; N | 1956 |
Convulsive reaction in a two-year-old child following the accidental ingestion of an overdosage of isoniazid.
Topics: Barbiturates; Child; Drug Overdose; Humans; Infant; Isoniazid; Niacin; Nicotinic Acids; Poisoning; S | 1956 |
[Some unusual effects of iproniazid. I. Anticonvulsive effect in epilepsy of the grand-mal type].
Topics: Epilepsy; Epilepsy, Tonic-Clonic; Iproniazid; Niacin; Nicotinic Acids; Seizures | 1959 |
[Effects of chronic treatment with procaine and p-aminobenzoic acid on audiogenic crises in the white rat sensitized by nicotinoylhydrazide].
Topics: 4-Aminobenzoic Acid; Animals; Learning; Nervous System Physiological Phenomena; Niacin; Nicotinic Ac | 1961 |
[Electroencephalographic aspects of 2 convulsive seizures induced by hydrazines in the mouse].
Topics: Animals; Electroencephalography; Humans; Hydrazines; Isoniazid; Mice; Niacin; Nicotinic Acids; Seizu | 1963 |
[SODIUM NITROPRUSSIATE IN TREATMENT OF HYPERTENSIVE ENCEPHALOPATHY DUE TO RENAL INSUFFICIENCY].
Topics: Angiography; Antihypertensive Agents; Coma; Cyanides; Electrocardiography; Humans; Hypertension; Hyp | 1964 |
[Isonicotinic acid hydrazide in the cerebrospinal fluid; pharmacological and toxicological research on monkeys and dogs].
Topics: Animals; Cerebrospinal Fluid; Dogs; Haplorhini; Isomerism; Isoniazid; Niacin; Nicotinic Acids; Resea | 1954 |
Characterization of the anticonvulsant profile of isonicotinic acid benzylamide in various experimental seizure models in mice.
Topics: Animals; Anticonvulsants; Behavior, Animal; Benzyl Compounds; Disease Models, Animal; Drug Interacti | 2007 |
Nicotinylalanine increases cerebral kynurenic acid content and has anticonvulsant activity.
Topics: Alanine; Animals; Anticonvulsants; Brain Chemistry; Electroshock; In Vitro Techniques; Kidney; Kynur | 1992 |
In vivo brain dialysis of amino acids and simultaneous EEG measurements following intrahippocampal quinolinic acid injection: evidence for a dissociation between neurochemical changes and seizures.
Topics: Amino Acids; Animals; Aspartic Acid; Brain; Dialysis; Electroencephalography; gamma-Aminobutyric Aci | 1985 |