sumatriptan has been researched along with Seizures in 11 studies
Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Serotonin and fluoxetine, but not sumatriptan, alleviated PTZ-induced seizures by prolonging onset times of myoclonic-jerk and generalized tonic-clonic seizures." | 8.12 | Endogenous and exogenous serotonin, but not sumatriptan, ameliorate seizures and neuroinflammation in the pentylenetetrazole-induced seizure model in rats. ( Kilinc, E; Kılınc, YB; Torun, IE, 2022) |
| " In this study, we investigated the possible beneficial effects of lasmiditan and sumatriptan against post-stroke seizures in mice and explored underlying mechanisms in their effects." | 8.12 | Neuroprotective effects of Lasmiditan and Sumatriptan in an experimental model of post-stroke seizure in mice: Higher effects with concurrent opioid receptors or K ( Amanlou, A; Dehpour, AR; Ejtemaei-Mehr, S; Eslami, F; Ghasemi, M; Rahimi, N; Rashidian, A; Shayan, M; Solaimanian, S, 2022) |
| "Sumatriptan has been among the top choices in the management of migraine headaches." | 5.48 | Biphasic effect of sumatriptan on PTZ-induced seizures in mice: Modulation by 5-HT1B/D receptors and NOS/NO pathway. ( Aghamollaii, V; Ahmadi, M; Amiri, S; Dehpour, AR; Ghasemi, K; Gooshe, M; Rohani, MM; Tafakhori, A, 2018) |
| "Sumatriptan has been used for the acute treatment of migraine attacks." | 5.46 | Sumatriptan, an Antimigraine Drug, Inhibits Pentylenetetrazol-induced Seizures in NMRI Mice. ( Jand, A; Palizvan, MR, 2017) |
| "Serotonin and fluoxetine, but not sumatriptan, alleviated PTZ-induced seizures by prolonging onset times of myoclonic-jerk and generalized tonic-clonic seizures." | 4.12 | Endogenous and exogenous serotonin, but not sumatriptan, ameliorate seizures and neuroinflammation in the pentylenetetrazole-induced seizure model in rats. ( Kilinc, E; Kılınc, YB; Torun, IE, 2022) |
| " In this study, we investigated the possible beneficial effects of lasmiditan and sumatriptan against post-stroke seizures in mice and explored underlying mechanisms in their effects." | 4.12 | Neuroprotective effects of Lasmiditan and Sumatriptan in an experimental model of post-stroke seizure in mice: Higher effects with concurrent opioid receptors or K ( Amanlou, A; Dehpour, AR; Ejtemaei-Mehr, S; Eslami, F; Ghasemi, M; Rahimi, N; Rashidian, A; Shayan, M; Solaimanian, S, 2022) |
| "Sumatriptan is a specific 5-Hydroxytryptamine 1B/1D receptor agonist and has neuroprotective effects in various neuropsychiatric disorders." | 1.72 | Neuroprotective effect of sumatriptan in pentylenetetrazole-induced seizure is mediated through N-methyl-D-aspartate/nitric oxide and cAMP response element-binding protein signaling pathway. ( Abdollahi, A; Alotaibi, G; Dehpour, AR; Ghazi-Khansari, M; Imran Khan, M; Mumtaz, F; Rashki, A; Shadboorestan, A, 2022) |
| "Sumatriptan has been among the top choices in the management of migraine headaches." | 1.48 | Biphasic effect of sumatriptan on PTZ-induced seizures in mice: Modulation by 5-HT1B/D receptors and NOS/NO pathway. ( Aghamollaii, V; Ahmadi, M; Amiri, S; Dehpour, AR; Ghasemi, K; Gooshe, M; Rohani, MM; Tafakhori, A, 2018) |
| "Sumatriptan has been used for the acute treatment of migraine attacks." | 1.46 | Sumatriptan, an Antimigraine Drug, Inhibits Pentylenetetrazol-induced Seizures in NMRI Mice. ( Jand, A; Palizvan, MR, 2017) |
| "All were treated for that headache with Synacthen and one also received sumatriptan before her seizures." | 1.31 | Unexplained fitting in three parturients suffering from postdural puncture headache. ( Oliver, CD; White, SA, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Mumtaz, F | 1 |
| Rashki, A | 1 |
| Imran Khan, M | 1 |
| Shadboorestan, A | 1 |
| Abdollahi, A | 1 |
| Ghazi-Khansari, M | 1 |
| Alotaibi, G | 1 |
| Dehpour, AR | 3 |
| Torun, IE | 1 |
| Kılınc, YB | 1 |
| Kilinc, E | 1 |
| Shayan, M | 1 |
| Eslami, F | 1 |
| Amanlou, A | 1 |
| Solaimanian, S | 1 |
| Rahimi, N | 1 |
| Rashidian, A | 1 |
| Ejtemaei-Mehr, S | 1 |
| Ghasemi, M | 1 |
| Gooshe, M | 1 |
| Ghasemi, K | 1 |
| Rohani, MM | 1 |
| Tafakhori, A | 1 |
| Amiri, S | 1 |
| Aghamollaii, V | 1 |
| Ahmadi, M | 1 |
| Levin, M | 1 |
| Jand, A | 1 |
| Palizvan, MR | 1 |
| Williams, SH | 1 |
| Kehr, HA | 1 |
| Oliver, CD | 1 |
| White, SA | 1 |
| Iizuka, T | 1 |
| Sakai, F | 1 |
| Endo, M | 1 |
| Suzuki, N | 1 |
| Chan, WN | 1 |
| Evans, JM | 1 |
| Hadley, MS | 1 |
| Herdon, HJ | 1 |
| Jerman, JC | 1 |
| Parsons, AA | 1 |
| Read, SJ | 1 |
| Stean, TO | 1 |
| Thompson, M | 1 |
| Upton, N | 1 |
| O'Quinn, S | 1 |
| Davis, RL | 1 |
| Gutterman, DL | 1 |
| Pait, GD | 1 |
| Fox, AW | 1 |
1 review available for sumatriptan and Seizures
| Article | Year |
|---|---|
An update in the treatment of neurologic disorders during pregnancy--focus on migraines and seizures.
Topics: Animals; Anticonvulsants; Female; Humans; Migraine Disorders; Nervous System Diseases; Pregnancy; Pr | 2012 |
1 trial available for sumatriptan and Seizures
| Article | Year |
|---|---|
Prospective large-scale study of the tolerability of subcutaneous sumatriptan injection for acute treatment of migraine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Cardiovascular Diseases; Cerebrovascul | 1999 |
9 other studies available for sumatriptan and Seizures
| Article | Year |
|---|---|
Neuroprotective effect of sumatriptan in pentylenetetrazole-induced seizure is mediated through N-methyl-D-aspartate/nitric oxide and cAMP response element-binding protein signaling pathway.
Topics: Animals; Cyclic AMP Response Element-Binding Protein; Mice; N-Methylaspartate; Neuroprotective Agent | 2022 |
Endogenous and exogenous serotonin, but not sumatriptan, ameliorate seizures and neuroinflammation in the pentylenetetrazole-induced seizure model in rats.
Topics: Animals; Anticonvulsants; Epilepsy; Fluoxetine; Humans; Interleukin-6; Male; Neuroinflammatory Disea | 2022 |
Neuroprotective effects of Lasmiditan and Sumatriptan in an experimental model of post-stroke seizure in mice: Higher effects with concurrent opioid receptors or K
Topics: Adenosine Triphosphate; Animals; Anticonvulsants; bcl-2-Associated X Protein; Benzamides; Disease Mo | 2022 |
Biphasic effect of sumatriptan on PTZ-induced seizures in mice: Modulation by 5-HT1B/D receptors and NOS/NO pathway.
Topics: Animals; Anticonvulsants; Convulsants; Dose-Response Relationship, Drug; Male; Mice; Nitric Oxide; N | 2018 |
Teaching case: hypertensiveheadache.
Topics: Brain Diseases; Cerebral Hemorrhage; Female; Headache; Humans; Hypertension; Middle Aged; Seizures; | 2013 |
Sumatriptan, an Antimigraine Drug, Inhibits Pentylenetetrazol-induced Seizures in NMRI Mice.
Topics: Animals; Anticonvulsants; Male; Mice; Migraine Disorders; Pentylenetetrazole; Seizures; Sumatriptan; | 2017 |
Unexplained fitting in three parturients suffering from postdural puncture headache.
Topics: Adult; Analgesia, Epidural; Anesthesia, Obstetrical; Cosyntropin; Female; Headache; Humans; Seizures | 2002 |
Response to sumatriptan in headache of MELAS syndrome.
Topics: Adult; Drug Evaluation; Female; Headache; Humans; Hyperemia; MELAS Syndrome; Parietal Lobe; Phenotyp | 2003 |
Identification of (-)-cis-6-acetyl-4S-(3-chloro-4-fluoro-benzoylamino)- 3,4-dihydro-2,2-dimethyl-2H-benzo[b]pyran-3S-ol as a potential antimigraine agent.
Topics: Animals; Benzamides; Benzopyrans; Dose-Response Relationship, Drug; Methylcellulose; Mice; Migraine | 1999 |