uric acid has been researched along with Seizures in 48 studies
Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
Excerpt | Relevance | Reference |
---|---|---|
"In this study, we examined the association between serum uric acid levels and epilepsy secondary to cerebral infarction." | 7.91 | Serum Uric Acid Is Highly Associated with Epilepsy Secondary to Cerebral Infarction. ( Cheng, F; Dai, Y; Feng, Y; Hu, B; Liu, Z; Sun, J; Wang, D; Zhang, X, 2019) |
" In this study we assessed the susceptibility to pentylenetetrazole- and pilocarpine-induced seizures in mice with genetically altered uric acid levels by targeting urate oxidase, which is the enzyme responsible for uric acid breakdown." | 7.83 | Disruption, but not overexpression of urate oxidase alters susceptibility to pentylenetetrazole- and pilocarpine-induced seizures in mice. ( Boon, P; Carrette, E; Delbeke, J; Glorieux, G; Larsen, LE; Portelli, J; Raedt, R; Sprengers, M; Thyrion, L; Van Lysebettens, W; Vonck, K, 2016) |
"Seizures, often with fatal outcome, are a manifestation of pronounced theophylline intoxication." | 7.67 | Kinetics of drug action in disease states. XVI. Pharmacodynamics of theophylline-induced seizures in rats. ( Levy, G; Ramzan, IM, 1986) |
"RSE was defined as seizure continuing after the first- and second-line treatments." | 5.51 | Uric acid is a useful marker to differentiate between responsive and refractory status epilepticus. ( Choi, JY; Hong, JM; Huh, K; Kim, BG; Kim, TJ, 2019) |
"This pharmacologic protection trial was conducted to test the hypothesis that allopurinol, a scavenger and inhibitor of oxygen free radical production, could reduce death, seizures, coma, and cardiac events in infants who underwent heart surgery using deep hypothermic circulatory arrest (DHCA)." | 5.09 | Allopurinol neurocardiac protection trial in infants undergoing heart surgery using deep hypothermic circulatory arrest. ( Clancy, RR; Gaynor, JW; Goin, JE; Hirtz, DG; Jacobs, ML; Mahle, WT; McGaurn, SA; Murphy, JD; Nicolson, SC; Norwood, WI; Spray, TL; Steven, JM; Wernovsky, G, 2001) |
"This study aimed to explore the value of serum uric acid levels in differentiating among GTCS, syncope, and PNES by analyzing serum uric acid levels in patients with GTCS, syncope, and PNES." | 3.91 | The value of serum uric acid levels to differentiate causes of transient loss of consciousness. ( Hu, H; Jiang, M; Wang, W; Yan, L; Yan, X, 2019) |
"In this study, we examined the association between serum uric acid levels and epilepsy secondary to cerebral infarction." | 3.91 | Serum Uric Acid Is Highly Associated with Epilepsy Secondary to Cerebral Infarction. ( Cheng, F; Dai, Y; Feng, Y; Hu, B; Liu, Z; Sun, J; Wang, D; Zhang, X, 2019) |
" In this study we assessed the susceptibility to pentylenetetrazole- and pilocarpine-induced seizures in mice with genetically altered uric acid levels by targeting urate oxidase, which is the enzyme responsible for uric acid breakdown." | 3.83 | Disruption, but not overexpression of urate oxidase alters susceptibility to pentylenetetrazole- and pilocarpine-induced seizures in mice. ( Boon, P; Carrette, E; Delbeke, J; Glorieux, G; Larsen, LE; Portelli, J; Raedt, R; Sprengers, M; Thyrion, L; Van Lysebettens, W; Vonck, K, 2016) |
" Univariate analysis revealed statistical significance for the following variables associated with eclampsia: systolic hypertension > or =160 mmHg and diastolic > or =110 mmHg, headache, visual symptoms, vivid deep tendon reflexes, proteinuria >3+ or >3 g d(-1), uric acid concentration > or =350 micromol l(-1), serum creatinine concentration >100 micromol l(-1) and aminotransferase aspartate >30 IU l(-1)." | 3.72 | [Risk factors for eclampsia: a case-control study]. ( Arfaoui, C; Ben Salem, F; Ben Salem, K; Faleh, R; Gahbiche, M; Grati, L; Guerdelly, I; Jmel, A, 2003) |
" The key findings leading to diagnosis were neonatal seizures unresponsive to treatment, craniofacial dysmorphic features, hyperexcitability, low blood uric acid levels, and neuroimaging findings." | 3.71 | Molybdenum cofactor deficiency: report of three cases presenting as hypoxic-ischemic encephalopathy. ( Coskun, T; Haliloglu, G; Saatci, I; Topcu, M, 2001) |
"Kainic acid (KA) causes seizures and extensive brain damage in rats." | 3.70 | Kainic acid causes redox changes in cerebral cortex extracellular fluid: NMDA receptor activity increases ascorbic acid whereas seizure activity increases uric acid. ( Layton, ME; Pazdernik, TL; Samson, FE, 1998) |
"Univariate analysis revealed statistical significance for the following variables associated with eclampsia: uric acid concentration, > 8." | 3.70 | Risk factors for abruptio placentae and eclampsia: analysis of 445 consecutively managed women with severe preeclampsia and eclampsia. ( Mattar, F; Saade, GR; Sibai, BM; Witlin, AG, 1999) |
"We describe a patient with carnitine-acylcarnitine translocase deficiency (MIM 212138), who presented with neonatal generalized seizures, heart failure, and coma." | 3.70 | Carnitine-acylcarnitine translocase deficiency: metabolic consequences of an impaired mitochondrial carnitine cycle. ( Dorland, L; Duran, M; IJlst, L; Muntau, AC; Roscher, AA; Röschinger, W; Wanders, RJ, 2000) |
"Seizures, often with fatal outcome, are a manifestation of pronounced theophylline intoxication." | 3.67 | Kinetics of drug action in disease states. XVI. Pharmacodynamics of theophylline-induced seizures in rats. ( Levy, G; Ramzan, IM, 1986) |
"Seizures in children with coronavirus disease 2019 (COVID-19) were markedly increased during the Omicron variant surge." | 1.91 | Afebrile benign convulsions with or without a reversible splenial lesion in two pediatric patients with COVID-19. ( Kim, YO; Lee, YY, 2023) |
"Of those, 80% had generalized seizures, 13." | 1.72 | Stroke Characteristics as Predictors of New-onset Seizure in Patients with Acute Ischemic Stroke. ( Ajmal, M; Bhat, NK; Dhar, M; Jose, A; Mohan, L; Saxena, Y, 2022) |
"RSE was defined as seizure continuing after the first- and second-line treatments." | 1.51 | Uric acid is a useful marker to differentiate between responsive and refractory status epilepticus. ( Choi, JY; Hong, JM; Huh, K; Kim, BG; Kim, TJ, 2019) |
"All compounds studied induced clonic convulsion in a dose-dependent manner, and the ED50 values for convulsion were 490, 546, 1107, 360 and 620 nmol/kg for theophylline, 1-MX, 3-MX, 1,3-DMUA and 1-MUA, respectively." | 1.29 | Neurotoxic convulsions induced by theophylline and its metabolites in mice. ( Iga, T; Kawakami, J; Sawada, Y; Toyama, E; Yamamoto, K, 1996) |
"Cardiazol induced seizures in rabbits showed that the highest oxypurine concentrations can be detected in the CSF 1 hour after the convulsions." | 1.26 | Increased nucleotide catabolism after cerebral convulsions. ( Dörner, K; Manzke, H; Staemmler, W, 1981) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 20 (41.67) | 18.7374 |
1990's | 10 (20.83) | 18.2507 |
2000's | 7 (14.58) | 29.6817 |
2010's | 6 (12.50) | 24.3611 |
2020's | 5 (10.42) | 2.80 |
Authors | Studies |
---|---|
Lee, HF | 1 |
Hsu, CC | 1 |
Chi, CS | 1 |
Tsai, CR | 1 |
Tomomitsu, Y | 1 |
Asakawa, S | 1 |
Arai, S | 1 |
Nagura, M | 1 |
Ishizawa, K | 1 |
Yamazaki, O | 1 |
Tamura, Y | 1 |
Uchida, S | 1 |
Ohashi, R | 1 |
Shibata, S | 1 |
Fujigaki, Y | 1 |
Lee, YY | 1 |
Kim, YO | 1 |
Jose, A | 1 |
Dhar, M | 1 |
Ajmal, M | 1 |
Mohan, L | 1 |
Saxena, Y | 1 |
Bhat, NK | 1 |
Jiang, M | 1 |
Yan, L | 1 |
Yan, X | 1 |
Wang, W | 1 |
Hu, H | 1 |
Mhanni, AA | 1 |
Greenberg, CR | 1 |
Spriggs, EL | 1 |
Agatep, R | 1 |
Sisk, RR | 1 |
Prasad, C | 1 |
Wang, D | 1 |
Hu, B | 1 |
Dai, Y | 1 |
Sun, J | 1 |
Liu, Z | 1 |
Feng, Y | 1 |
Cheng, F | 1 |
Zhang, X | 1 |
Choi, JY | 1 |
Hong, JM | 1 |
Kim, TJ | 1 |
Kim, BG | 1 |
Huh, K | 1 |
Thyrion, L | 2 |
Raedt, R | 2 |
Portelli, J | 2 |
Van Loo, P | 1 |
Wadman, WJ | 1 |
Glorieux, G | 2 |
Lambrecht, BN | 1 |
Janssens, S | 1 |
Vonck, K | 2 |
Boon, P | 2 |
Larsen, LE | 1 |
Sprengers, M | 1 |
Van Lysebettens, W | 1 |
Carrette, E | 1 |
Delbeke, J | 1 |
Jurecka, A | 1 |
Tylki-Szymanska, A | 1 |
Zikanova, M | 1 |
Krijt, J | 1 |
Kmoch, S | 1 |
Tsujita, Y | 1 |
Matsumoto, H | 1 |
Nakamura, Y | 1 |
Nonoyama, S | 1 |
SONDERGAARD, E | 1 |
PRANGE, I | 1 |
DAM, H | 1 |
CHRISTENSEN, E | 1 |
SALISBURY, PF | 1 |
POMERANZ, AA | 1 |
Ben Salem, F | 1 |
Ben Salem, K | 1 |
Grati, L | 1 |
Arfaoui, C | 1 |
Faleh, R | 1 |
Jmel, A | 1 |
Guerdelly, I | 1 |
Gahbiche, M | 1 |
ALTSCHULE, MD | 1 |
ALTSCHULE, LH | 1 |
TILLOTSON, KJ | 1 |
Grisar, T | 1 |
Manzke, H | 1 |
Staemmler, W | 1 |
Dörner, K | 1 |
Schattner, A | 1 |
Bar-Khaim, Y | 1 |
Pohlmann-Eden, B | 1 |
Wellhäusser, H | 1 |
Stefanou, A | 1 |
Schmidt, R | 1 |
Schmidt, H | 1 |
Siems, WG | 1 |
Grune, T | 1 |
Grauel, EL | 1 |
Yamamoto, K | 1 |
Toyama, E | 1 |
Kawakami, J | 1 |
Sawada, Y | 1 |
Iga, T | 1 |
Sumi, S | 1 |
Wada, Y | 1 |
Mayatepek, E | 1 |
Koch, HG | 1 |
Hoffmann, GF | 2 |
Layton, ME | 1 |
Samson, FE | 1 |
Pazdernik, TL | 1 |
Koch, H | 1 |
Waring, WS | 1 |
Maxwell, S | 1 |
Simmonds, HA | 1 |
Pérignon, JL | 1 |
Micheli, V | 1 |
van Gennip, AH | 1 |
Witlin, AG | 1 |
Saade, GR | 1 |
Mattar, F | 1 |
Sibai, BM | 1 |
Röschinger, W | 1 |
Muntau, AC | 1 |
Duran, M | 1 |
Dorland, L | 1 |
IJlst, L | 1 |
Wanders, RJ | 1 |
Roscher, AA | 1 |
Kavukçu, S | 1 |
Soylu, A | 1 |
Sahin, B | 1 |
Türkmen, M | 1 |
Aydin, A | 1 |
Dirik, E | 1 |
Topcu, M | 1 |
Coskun, T | 1 |
Haliloglu, G | 1 |
Saatci, I | 1 |
Clancy, RR | 1 |
McGaurn, SA | 1 |
Goin, JE | 1 |
Hirtz, DG | 1 |
Norwood, WI | 1 |
Gaynor, JW | 1 |
Jacobs, ML | 1 |
Wernovsky, G | 1 |
Mahle, WT | 1 |
Murphy, JD | 1 |
Nicolson, SC | 1 |
Steven, JM | 1 |
Spray, TL | 1 |
Alvarez Navascués, R | 1 |
Marín, R | 1 |
Duvina, PL | 1 |
Bueno, F | 1 |
Mezey, E | 1 |
Matsuo, M | 1 |
Maeda, E | 1 |
Nakamura, H | 1 |
Saiki, K | 1 |
Ramzan, IM | 1 |
Levy, G | 1 |
Paulson, GW | 2 |
Nance, W | 1 |
Son, C | 1 |
Son, CD | 1 |
Nance, WE | 1 |
Berlyne, GM | 1 |
Shaw, AB | 1 |
Nilwarangkur, S | 1 |
Coleman, M | 2 |
Landgrebe, M | 1 |
Landgrebe, A | 1 |
Kelly, S | 1 |
Hart, EJ | 1 |
Desjardins, L | 1 |
Chini, V | 1 |
Galli, S | 1 |
Quigley, MM | 1 |
Morrison, JC | 1 |
Whybrew, DW | 1 |
Wiser, WL | 1 |
Bucovaz, ET | 1 |
Fish, SA | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Use of the Cardioprotectant Dexrazoxane During Congenital Heart Surgery: Proposal for Pilot Investigation[NCT02519335] | Phase 1 | 12 participants (Actual) | Interventional | 2014-09-30 | Terminated (stopped due to PI no longer at this facility) | ||
Use of the Cardioprotectant Dexrazoxane During Congenital Heart Surgery[NCT04997291] | Phase 1 | 12 participants (Anticipated) | Interventional | 2021-04-09 | Recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
2 reviews available for uric acid and Seizures
Article | Year |
---|---|
[Xanthine oxidase deficiency (hereditary xanthinuria), molybdenum cofactor deficiency].
Topics: Central Nervous System Diseases; Coenzymes; Diagnosis, Differential; Diet Therapy; Humans; Infant, N | 1996 |
[Severe maternal complications associated with pre-eclampsia: an almost forgotten pathology?].
Topics: Abruptio Placentae; Adult; Anemia, Hemolytic; Case-Control Studies; Cesarean Section; Critical Care; | 2001 |
1 trial available for uric acid and Seizures
Article | Year |
---|---|
Allopurinol neurocardiac protection trial in infants undergoing heart surgery using deep hypothermic circulatory arrest.
Topics: Allopurinol; Cardiac Surgical Procedures; Coma; Death, Sudden, Cardiac; Female; Free Radical Scaveng | 2001 |
Allopurinol neurocardiac protection trial in infants undergoing heart surgery using deep hypothermic circulatory arrest.
Topics: Allopurinol; Cardiac Surgical Procedures; Coma; Death, Sudden, Cardiac; Female; Free Radical Scaveng | 2001 |
Allopurinol neurocardiac protection trial in infants undergoing heart surgery using deep hypothermic circulatory arrest.
Topics: Allopurinol; Cardiac Surgical Procedures; Coma; Death, Sudden, Cardiac; Female; Free Radical Scaveng | 2001 |
Allopurinol neurocardiac protection trial in infants undergoing heart surgery using deep hypothermic circulatory arrest.
Topics: Allopurinol; Cardiac Surgical Procedures; Coma; Death, Sudden, Cardiac; Female; Free Radical Scaveng | 2001 |
45 other studies available for uric acid and Seizures
Article | Year |
---|---|
Genotype-Phenotype Dissociation in Two Taiwanese Children with Molybdenum Cofactor Deficiency Caused by MOCS2 Mutation.
Topics: Child; Homozygote; Humans; Magnetic Resonance Imaging; Metal Metabolism, Inborn Errors; Movement Dis | 2022 |
A Patient with Acute Kidney Injury Associated with Massive Proteinuria and Acute Hyperuricemia after Epileptic Seizures.
Topics: Acute Kidney Injury; Adult; Epilepsy; Humans; Hyperuricemia; Kidney; Male; Proteinuria; Seizures; Ur | 2022 |
Afebrile benign convulsions with or without a reversible splenial lesion in two pediatric patients with COVID-19.
Topics: Child; COVID-19; Fever; Humans; Infant, Newborn; Magnetic Resonance Imaging; SARS-CoV-2; Seizures; U | 2023 |
Stroke Characteristics as Predictors of New-onset Seizure in Patients with Acute Ischemic Stroke.
Topics: Anticonvulsants; Female; Humans; Ischemic Stroke; Male; Middle Aged; Seizures; Stroke; Uric Acid | 2022 |
The value of serum uric acid levels to differentiate causes of transient loss of consciousness.
Topics: Adult; Aged; Consciousness Disorders; Diagnosis, Differential; Female; Humans; Male; Middle Aged; Re | 2019 |
Isolated sulfite oxidase deficiency: a founder mutation.
Topics: Amino Acid Metabolism, Inborn Errors; Female; Genetic Predisposition to Disease; Humans; Male; Mutat | 2020 |
Serum Uric Acid Is Highly Associated with Epilepsy Secondary to Cerebral Infarction.
Topics: Biomarkers; Cerebral Infarction; Epilepsy; Female; Humans; Male; Middle Aged; Risk Factors; Seizures | 2019 |
Uric acid is a useful marker to differentiate between responsive and refractory status epilepticus.
Topics: Adult; Aged; Anticonvulsants; Biomarkers; Female; Hospitalization; Humans; Intensive Care Units; Mal | 2019 |
Uric acid is released in the brain during seizure activity and increases severity of seizures in a mouse model for acute limbic seizures.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Electroencephalography; Excitatory Amino Acid | 2016 |
Disruption, but not overexpression of urate oxidase alters susceptibility to pentylenetetrazole- and pilocarpine-induced seizures in mice.
Topics: Animals; Brain; Convulsants; Disease Models, Animal; Disease Susceptibility; Mice; Mice, Inbred C57B | 2016 |
D-ribose therapy in four Polish patients with adenylosuccinate lyase deficiency: absence of positive effect.
Topics: Adenosine; Adenylosuccinate Lyase; Aminoimidazole Carboxamide; Autistic Disorder; Blood Glucose; Chi | 2008 |
[Analysis of the blood and serum biochemistry findings in patients demonstrating convulsion with mild gastroenteritis].
Topics: Acidosis; Blood Cell Count; Chlorides; Female; Gastroenteritis; Humans; Infant; Male; Seizures; Uric | 2011 |
Uricemia and kidney damage in galactose-poisoned chicks.
Topics: Animals; Chickens; Galactose; Humans; Kidney; Seizures; Uric Acid | 1957 |
UREMIC TOXICITY CORRELATED WITH UNIDENTIFIED ANIONS.
Topics: Anions; Blood Chemical Analysis; Creatine; Creatinine; Edema; Glomerulonephritis; Ileostomy; Kidney; | 1963 |
[Risk factors for eclampsia: a case-control study].
Topics: Adult; Analysis of Variance; Aspartate Aminotransferases; Case-Control Studies; Creatinine; Eclampsi | 2003 |
Changes in urinary uric acid-creatinine ratio after electrically induced convulsions in man.
Topics: Creatinine; Humans; Male; Seizures; Uric Acid; Urine | 1949 |
Argininosuccinic aciduria in adult: a clinical, electrophysiological and biochemical study.
Topics: Age Factors; Amino Acid Metabolism, Inborn Errors; Ammonia; Arginine; Argininosuccinic Acid; Arginin | 1982 |
Increased nucleotide catabolism after cerebral convulsions.
Topics: Animals; Child; Epilepsy; Female; Humans; Hypoxanthines; Nucleotides; Pentylenetetrazole; Rabbits; S | 1981 |
[Renal damage following encephalitis and convulsions].
Topics: Adult; Encephalitis; Humans; Kidney Diseases; Male; Remission, Spontaneous; Seizures; Uric Acid | 1981 |
[Correlation of serum prolactin and cortisol values with paroxysmal disorders of epileptic and non-epileptic origin and their clinical value].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Diagnosis, Differential; Electroencephalography; Epileps | 1993 |
Concentration of purine compounds in the cerebrospinal fluid of infants suffering from sepsis, convulsions and hydrocephalus.
Topics: Adenine; Bacterial Infections; Chromatography, High Pressure Liquid; Humans; Hydrocephalus; Hypoxant | 1995 |
Neurotoxic convulsions induced by theophylline and its metabolites in mice.
Topics: Animals; Blood-Brain Barrier; Brain; Infusions, Intravenous; Injections, Intraventricular; Male; Mic | 1996 |
Hyperuricaemia and medium-chain acyl-CoA dehydrogenase deficiency.
Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Blood Glucose; Brain Edema; Female; Humans; Hypogly | 1997 |
Kainic acid causes redox changes in cerebral cortex extracellular fluid: NMDA receptor activity increases ascorbic acid whereas seizure activity increases uric acid.
Topics: Animals; Antioxidants; Ascorbic Acid; Cerebral Cortex; Excitatory Amino Acid Agonists; Extracellular | 1998 |
Dipsticks and convulsions.
Topics: Coenzymes; Diagnostic Errors; Humans; Infant, Newborn; Male; Metalloproteins; Molybdenum Cofactors; | 1998 |
Diagnosis of molybdenum cofactor deficiency.
Topics: Antioxidants; Coenzymes; Diagnosis, Differential; Free Radical Scavengers; Free Radicals; Humans; Hy | 1999 |
Diagnosis of molybdenum cofactor deficiency.
Topics: Child, Preschool; Coenzymes; Diagnosis, Differential; Humans; Infant; Infant, Newborn; Metalloprotei | 1999 |
Risk factors for abruptio placentae and eclampsia: analysis of 445 consecutively managed women with severe preeclampsia and eclampsia.
Topics: Abruptio Placentae; Adolescent; Adult; Blood Pressure; Eclampsia; Female; Headache; Humans; Logistic | 1999 |
Carnitine-acylcarnitine translocase deficiency: metabolic consequences of an impaired mitochondrial carnitine cycle.
Topics: Ammonia; Cardiac Output, Low; Carnitine; Carnitine Acyltransferases; Cells, Cultured; Coma; Consangu | 2000 |
Clinical quiz. Molybdenum cofactor deficiency.
Topics: Coenzymes; Encephalomalacia; Hematuria; Humans; Infant; Male; Metabolism, Inborn Errors; Metalloprot | 2000 |
Molybdenum cofactor deficiency: report of three cases presenting as hypoxic-ischemic encephalopathy.
Topics: Coenzymes; Diagnosis, Differential; Female; Humans; Hypoxia-Ischemia, Brain; Infant; Infant, Newborn | 2001 |
[9 years of diazoxide therapy in a case of infantile idiopathic hypolglycemia].
Topics: Child; Diazoxide; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Male; Prediabetic State; Se | 1978 |
[Therapy of alcoholism].
Topics: Acute Disease; Alcohol Withdrawal Delirium; Alcoholic Intoxication; Alcoholism; Avitaminosis; Chroni | 1976 |
Molybdenum cofactor deficiency: another inborn error of metabolism with neonatal onset.
Topics: Coenzymes; Humans; Infant, Newborn; Metabolism, Inborn Errors; Metalloproteins; Molybdenum Cofactors | 1988 |
Kinetics of drug action in disease states. XVI. Pharmacodynamics of theophylline-induced seizures in rats.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Female; Half-Life; Kinetics; Rats; Rats, Inbred Le | 1986 |
Neurologic aspects of typical and atypical Down's syndrome.
Topics: Child; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Down Syndrome; Electroencepha | 1968 |
Neurologic aspects of typical and atypical Down's syndrome.
Topics: Cataract; Chromosome Aberrations; Down Syndrome; Gait; Humans; Hydroxyindoleacetic Acid; Intelligenc | 1969 |
Dietary treatment of chronic renal failure. Experiences with a modified Giovannetti diet.
Topics: Acidosis; Acute Kidney Injury; Adolescent; Adult; Aged; Arteritis; Dietary Proteins; Edema; Female; | 1965 |
Progressive seizures with hyperuricosuria reversed by allopurinol.
Topics: Allopurinol; Anticonvulsants; Child; Child, Preschool; Electroencephalography; Humans; Infant; Intel | 1974 |
A new HGPRT-deficient phenotype?
Topics: Adolescent; Guanine; Humans; Hypoxanthines; Intellectual Disability; Male; Metabolism, Inborn Errors | 1972 |
[Arterial hypertension with convulsive seizures in a patient with right kidney hypoplasia and gout attacks and with a probable gouty kidney].
Topics: Electrocardiography; Gout; Headache; Heart; Humans; Hydronephrosis; Hypertension; Kidney; Kidney Dis | 1973 |
[Behavior of uric acid and urinary ketone bodies in convulsive syndromes in childhood].
Topics: Calcium; Child; Child, Preschool; Female; Humans; Infant; Ketone Bodies; Male; Nitrogen; Seizures; U | 1973 |
Acute obstetric yellow atrophy presenting as idiopathic hyperuricemia.
Topics: Acute Kidney Injury; Adult; Blood Coagulation Tests; Bronchopneumonia; Cytoplasm; Diagnosis, Differe | 1974 |
Laboratory characteristics in toxemia.
Topics: Blood Glucose; Blood Proteins; Calcium; Cerebrospinal Fluid Proteins; Color; Erythrocytes; Female; G | 1972 |
Reversal of organic brain syndrome with seizures and hyperuricosuria subsequent to allopurinol therapy.
Topics: Allopurinol; Brain Damage, Chronic; Child; Electroencephalography; Humans; Male; Purine-Pyrimidine M | 1971 |