tetraisopropylpyrophosphamide has been researched along with Seizures in 2 studies
Tetraisopropylpyrophosphamide: N,N',N'',N'''-Tetraisopropylpyrophosphamide. A specific inhibitor of pseudocholinesterases. It is commonly used experimentally to determine whether pseudo- or acetylcholinesterases are involved in an enzymatic process.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Each pretreatment produced a statistically significant increase in cocaine lethality throughout the dose-response curve." | 1.28 | Decreased plasma cholinesterase activity enhances cocaine toxicity in mice. ( Goldfrank, LR; Henry, GC; Hoffman, RS; Howland, MA; Wax, PM; Weisman, RS, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, ZP | 1 |
| Dettbarn, WD | 1 |
| Hoffman, RS | 1 |
| Henry, GC | 1 |
| Wax, PM | 1 |
| Weisman, RS | 1 |
| Howland, MA | 1 |
| Goldfrank, LR | 1 |
2 other studies available for tetraisopropylpyrophosphamide and Seizures
| Article | Year |
|---|---|
Prevention of tolerance to the organophosphorus anticholinesterase paraoxon with carboxylesterase inhibitors.
Topics: Acetylcholinesterase; Animals; Brain; Butyrylcholinesterase; Carboxylesterase; Carboxylic Ester Hydr | 1998 |
Decreased plasma cholinesterase activity enhances cocaine toxicity in mice.
Topics: Animals; Cholinesterases; Cocaine; Dose-Response Relationship, Drug; Drug Interactions; Erythrocytes | 1992 |