Page last updated: 2024-11-04

sulpiride and Seizures

sulpiride has been researched along with Seizures in 10 studies

Sulpiride: A dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid. (From Merck Index, 11th ed)
sulpiride : A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"Cocaine produces not only euphoric effects but also a wide range of detrimental effects, including seizures and lethality."3.69Differential effects of NMDA receptor and dopamine receptor antagonists on cocaine toxicities. ( Marley, RJ; Saito, T; Shimosato, K, 1995)
"Seizures were induced in adult rats by stimulating the perforant path in a semi-rapid kindling method."1.91Involvement of dopamine D ( Asgari, A; Barkley, V; Fathollahi, Y; Ghafouri, S; Mirnajafi-Zadeh, J; Rezaei, M; Rostami, S; Shojaei, A, 2023)
"Seizures were assessed in terms of a composite seizure severity score (SSS), time of the onset of straub-like tail, onset of jerky movements of whole body, convulsions and death."1.37Amisulpride-induced seizurogenic effect: a potential role of opioid receptor-linked transduction systems. ( Chand, P; Rehni, AK; Singh, TG, 2011)
"Antipsychotic drugs can influence both seizure threshold and seizure activity in different ways."1.32The impact of neuroleptic medication on seizure threshold and duration in electroconvulsive therapy. ( Barna, I; Gazdag, G; Iványi, Z; Tolna, J, 2004)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's3 (30.00)18.2507
2000's3 (30.00)29.6817
2010's2 (20.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Rezaei, M2
Ghafouri, S2
Asgari, A2
Barkley, V2
Fathollahi, Y2
Rostami, S2
Shojaei, A2
Mirnajafi-Zadeh, J2
Hidaka, N1
Suemaru, K1
Araki, H1
Rehni, AK1
Singh, TG1
Chand, P1
Gazdag, G1
Barna, I1
Iványi, Z1
Tolna, J1
Shimosato, K1
Marley, RJ1
Saito, T1
Bourne, JA2
Fosbraey, P2
Halliday, J2
Maj, J1
Rogóz, Z1
Skuza, G1
Sowińska, H1
Wahnschaffe, U1
Löscher, W1
Georgiev, V1
György, L1
Getova, D1
Markovska, V1

Other Studies

10 other studies available for sulpiride and Seizures

ArticleYear
Involvement of dopamine D
    CNS neuroscience & therapeutics, 2023, Volume: 29, Issue:2

    Topics: Animals; Deep Brain Stimulation; Dopamine; Electric Stimulation; Kindling, Neurologic; Rats; Rats, W

2023
Involvement of dopamine D
    CNS neuroscience & therapeutics, 2023, Volume: 29, Issue:2

    Topics: Animals; Deep Brain Stimulation; Dopamine; Electric Stimulation; Kindling, Neurologic; Rats; Rats, W

2023
Involvement of dopamine D
    CNS neuroscience & therapeutics, 2023, Volume: 29, Issue:2

    Topics: Animals; Deep Brain Stimulation; Dopamine; Electric Stimulation; Kindling, Neurologic; Rats; Rats, W

2023
Involvement of dopamine D
    CNS neuroscience & therapeutics, 2023, Volume: 29, Issue:2

    Topics: Animals; Deep Brain Stimulation; Dopamine; Electric Stimulation; Kindling, Neurologic; Rats; Rats, W

2023
Serotonin-dopamine antagonism ameliorates impairments of spontaneous alternation and locomotor hyperactivity induced by repeated electroconvulsive seizures in rats.
    Epilepsy research, 2010, Volume: 90, Issue:3

    Topics: Analysis of Variance; Animals; Behavior, Animal; Dopamine Antagonists; Electroshock; Haloperidol; Hy

2010
Amisulpride-induced seizurogenic effect: a potential role of opioid receptor-linked transduction systems.
    Basic & clinical pharmacology & toxicology, 2011, Volume: 108, Issue:5

    Topics: Amines; Amisulpride; Analysis of Variance; Animals; Anti-Asthmatic Agents; Cromolyn Sodium; Cyclohex

2011
The impact of neuroleptic medication on seizure threshold and duration in electroconvulsive therapy.
    Ideggyogyaszati szemle, 2004, Nov-20, Volume: 57, Issue:11-12

    Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; Brain; Clopenthixol; Clozapine; Dibenzothiazepin

2004
Differential effects of NMDA receptor and dopamine receptor antagonists on cocaine toxicities.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 51, Issue:4

    Topics: Animals; Benzazepines; Cocaine; Dizocilpine Maleate; Dopamine Antagonists; Dose-Response Relationshi

1995
SCH 23390 affords protection against soman-evoked seizures in the freely moving guinea-pig: a concomitant neurochemical, electrophysiological and behavioural study.
    Neuropharmacology, 2001, Volume: 40, Issue:2

    Topics: Animals; Atropine Derivatives; Benzazepines; Chemical Warfare Agents; Cholinesterase Inhibitors; Chr

2001
Changes in striatal electroencephalography and neurochemistry induced by kainic acid seizures are modified by dopamine receptor antagonists.
    European journal of pharmacology, 2001, Feb-16, Volume: 413, Issue:2-3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Benzazepines; Corpus Striatum; Dopamine; Dop

2001
The effect of antidepressant drugs on the locomotor hyperactivity induced by MK-801, a non-competitive NMDA receptor antagonist.
    Neuropharmacology, 1992, Volume: 31, Issue:7

    Topics: Animals; Antidepressive Agents; Benzazepines; Citalopram; Dizocilpine Maleate; Fluoxetine; Imipramin

1992
Anticonvulsant effects of ipsilateral but not contralateral microinjections of the dopamine D2 agonist LY 171555 into the nucleus accumbens of amygdala-kindled rats.
    Brain research, 1991, Jul-12, Volume: 553, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Amygdala; Animals; Anticonvulsants; Dopa

1991
Some central effects of angiotensin II. Interactions with dopaminergic transmission.
    Acta physiologica et pharmacologica Bulgarica, 1985, Volume: 11, Issue:4

    Topics: Angiotensin II; Animals; Apomorphine; Behavior, Animal; Dopamine; Exploratory Behavior; Male; Mice;

1985