Page last updated: 2024-08-24

dexmedetomidine and Seizures

dexmedetomidine has been researched along with Seizures in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.45)18.2507
2000's10 (34.48)29.6817
2010's11 (37.93)24.3611
2020's7 (24.14)2.80

Authors

AuthorsStudies
Arslan, G; Cetindag Ciltas, A; Gumus, E; Gunes, H; Ozdemir, E; Taskiran, AS1
Xiao, Q; Xu, J1
De Martino, M; Deana, C; Furlan, D; Isola, M; Ius, T; Lettieri, C; Mauro, S; Nilo, A; Pauletto, G; Pez, S; Skrap, M; Tomasino, B; Valente, M; Verriello, L; Vetrugno, L1
Mahajan, C; Rath, GP1
Guo, N; Hei, Z; Huang, P; Li, X; Qiu, Z; Xiang, P; Zhang, M; Zhou, S1
Collier, TE; Farrell, LB; Kataria, VK; Killian, AD1
Bernstein, M; Chowdhury, T; Daniels, A; Leong, KW; Paquin-Lanthier, G; Singh, K; Subramaniam, S; Takami, H; Venkatraghavan, L1
Chen, G; Han, YG; Lei, M; Liu, XQ; Xu, KL; Yao, YL; Ye, MR; Zhang, T1
Chen, H; Cheng, L; Han, W; Jiang, L; Li, P; Liu, W; Song, X; Tan, X; Tu, S; Tu, Z1
Chiu, KM; Lee, MY; Lin, TY; Lu, CW; Wang, MJ; Wang, SJ1
Ben-Menachem, E; Ben-Zeev, B; Berkenstadt, H; Keidan, I; Tzadok, M1
Chen, GZ; Cui, YY; Kaye, AD; Mei, XP; Shen, XF; Wu, HH; Yin, JB; Zhai, MZ; Zhang, H; Zhu, X1
Clark-Price, SC; Lascola, KM; Schaeffer, DJ1
Eguchi, T; Kawano, Y; Ninomiya, Y; Nomura, Y; Takahashi, Y; Ueno, K1
Chandramouli, BA; Sheshadri, V1
Chen, SB; Hou, BC; Huang, J; Liu, WC; Luo, XL; Wang, XF; Zhan, YP1
Cheng, N; Guo, N; Hei, ZQ; Li, X; Tan, F; Zhong, ZY; Zhou, SL; Zhu, QQ1
Bekker, A; Chan, J; Doyle, W; Huncke, T; Kim, J1
Ishifuji, S; Kai, T; Morita, I; Okamoto, T; Taoda, M1
Bulut, M; Ganidagli, S; Koruk, S; Mizrak, A; Oner, U1
Akin, A; Boyaci, A; Esmaoglu, A; Ulgey, A1
Libenson, MH; Mason, KP; O'Mahony, E; Zurakowski, D1
Bronster, D; Nomoto, K; Scurlock, C1
Cooper, TB; Morishima, HO; Virag, L; Vulliemoz, Y; Whittington, RA1
Nakao, S1
Asada, A; Funao, T; Hamaoka, N; Oda, Y; Takahashi, R; Tanaka, K1
Everett, LL; Ojemann, JG; Saneto, RP; Shurtleff, HA; van Rooyen, IF; Warner, MH1
Begec, Z; Demirbilek, S; Erdil, F; Ersoy, MO; Onal, D; Toprak, HI1
Adachi, T; Kurata, J; Miyazaki, Y; Segawa, H; Shichino, T; Utsumi, J1

Reviews

1 review(s) available for dexmedetomidine and Seizures

ArticleYear
Dexmedetomidine Combined With Intravenous Anesthetics in Electroconvulsive Therapy: A Meta-analysis and Systematic Review.
    The journal of ECT, 2017, Volume: 33, Issue:3

    Topics: Anesthesia; Anesthetics; Dexmedetomidine; Drug Therapy, Combination; Electroconvulsive Therapy; Humans; Hypnotics and Sedatives; Seizures

2017

Trials

4 trial(s) available for dexmedetomidine and Seizures

ArticleYear
Preventive effect of dexmedetomidine on postictal delirium after electroconvulsive therapy: A randomised controlled study.
    European journal of anaesthesiology, 2020, Volume: 37, Issue:1

    Topics: Adolescent; Adult; Delirium; Dexmedetomidine; Double-Blind Method; Electroconvulsive Therapy; Female; Humans; Hypnotics and Sedatives; Incidence; Male; Mental Disorders; Prospective Studies; Seizures; Treatment Outcome; Young Adult

2020
Premedication with dexmedetomidine and midazolam attenuates agitation after electroconvulsive therapy.
    Journal of anesthesia, 2009, Volume: 23, Issue:1

    Topics: Adult; Anesthesia; Bipolar Disorder; Blood Pressure; Depressive Disorder, Major; Dexmedetomidine; Electroconvulsive Therapy; Female; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Premedication; Propofol; Psychomotor Agitation; Respiratory Insufficiency; Seizures

2009
Comparison between dexmedetomidine and midazolam for sedation of eclampsia patients in the intensive care unit.
    Journal of critical care, 2009, Volume: 24, Issue:4

    Topics: Adult; Blood Pressure; Dexmedetomidine; Eclampsia; Female; Heart Rate; Humans; Hypnotics and Sedatives; Intensive Care Units; Midazolam; Pregnancy; Prospective Studies; Seizures

2009
Dexmedetomidine blunts acute hyperdynamic responses to electroconvulsive therapy without altering seizure duration.
    Acta anaesthesiologica Scandinavica, 2008, Volume: 52, Issue:2

    Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Blood Pressure; Cross-Over Studies; Dexmedetomidine; Double-Blind Method; Electroconvulsive Therapy; Female; Heart Rate; Humans; Male; Middle Aged; Neuromuscular Depolarizing Agents; Propofol; Seizures; Sodium Chloride; Succinylcholine; Time Factors

2008

Other Studies

24 other study(ies) available for dexmedetomidine and Seizures

ArticleYear
The Anticonvulsant Effects of Alpha-2 Adrenoceptor Agonist Dexmedetomidine on Pentylenetetrazole-Induced Seizures in Rats.
    Neurochemical research, 2022, Volume: 47, Issue:2

    Topics: Animals; Anticonvulsants; Dexmedetomidine; Male; Pentylenetetrazole; Rats; Rats, Wistar; Receptors, Adrenergic; Seizures

2022
Assessment of the effects of dexmedetomidine on outcomes of traumatic brain injury using propensity score analysis.
    BMC anesthesiology, 2022, 09-02, Volume: 22, Issue:1

    Topics: Brain Injuries; Brain Injuries, Traumatic; Dexmedetomidine; Glasgow Coma Scale; Humans; Hypotension; Propensity Score; Seizures

2022
Effect of Dexmedetomidine versus Propofol on Intraoperative Seizure Onset During Awake Craniotomy: A Retrospective Study.
    World neurosurgery, 2023, Volume: 172

    Topics: Adult; Craniotomy; Dexmedetomidine; Epilepsy; Humans; Hypnotics and Sedatives; Propofol; Retrospective Studies; Seizures; Wakefulness

2023
Quest for an ideal anesthetic agent in awake craniotomy: Intraoperative seizures an important concern.
    Clinical neurology and neurosurgery, 2023, Volume: 231

    Topics: Anesthetics; Brain Neoplasms; Conscious Sedation; Craniotomy; Dexmedetomidine; Humans; Hypnotics and Sedatives; Seizures; Wakefulness

2023
Effect of Adjunctive Dexmedetomidine in the Treatment of Alcohol Withdrawal Compared to Benzodiazepine Symptom-Triggered Therapy in Critically Ill Patients: The EvADE Study.
    Journal of pharmacy practice, 2022, Volume: 35, Issue:3

    Topics: Alcoholism; Benzodiazepines; Cohort Studies; Critical Illness; Dexmedetomidine; Ethanol; Humans; Retrospective Studies; Seizures; Substance Withdrawal Syndrome

2022
Risk Factors and Characteristics of Intraoperative Seizures During Awake Craniotomy: A Retrospective Cohort Study of 562 Consecutive Patients With a Space-occupying Brain Lesion.
    Journal of neurosurgical anesthesiology, 2023, Apr-01, Volume: 35, Issue:2

    Topics: Brain; Brain Neoplasms; Craniotomy; Dexmedetomidine; Humans; Retrospective Studies; Risk Factors; Seizures; Wakefulness

2023
Effect of dexmedetomidine on rats with convulsive status epilepticus and association with activation of cholinergic anti-inflammatory pathway.
    Biochemical and biophysical research communications, 2018, 01-01, Volume: 495, Issue:1

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Anticonvulsants; Brain-Derived Neurotrophic Factor; Dexmedetomidine; Hippocampus; Interleukin-1beta; Long-Term Potentiation; Male; Memory; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus; Tumor Necrosis Factor-alpha

2018
Anticonvulsant and Neuroprotective Effects of Dexmedetomidine on Pilocarpine-Induced Status Epilepticus in Rats Using a Metabolomics Approach.
    Medical science monitor : international medical journal of experimental and clinical research, 2019, Mar-20, Volume: 25

    Topics: Animals; Anticonvulsants; Brain; Chromatography, Liquid; Dexmedetomidine; Disease Models, Animal; Hippocampus; Hypnotics and Sedatives; Metabolomics; Neurons; Neuroprotective Agents; Pilocarpine; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus; Tandem Mass Spectrometry

2019
Dexmedetomidine protects neurons from kainic acid-induced excitotoxicity by activating BDNF signaling.
    Neurochemistry international, 2019, Volume: 129

    Topics: Animals; Anticonvulsants; Apoptosis; Brain-Derived Neurotrophic Factor; Dexmedetomidine; Drug Evaluation, Preclinical; Glutamic Acid; Hippocampus; Kainic Acid; Male; MAP Kinase Signaling System; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Rats; Rats, Sprague-Dawley; Receptor, trkB; Seizures

2019
Electroencephalography for children with autistic spectrum disorder: a sedation protocol.
    Paediatric anaesthesia, 2015, Volume: 25, Issue:2

    Topics: Analgesics; Anesthesia; Autism Spectrum Disorder; Child; Child, Preschool; Chloral Hydrate; Dexmedetomidine; Electroencephalography; Female; Humans; Hypnotics and Sedatives; Ketamine; Male; Prospective Studies; Seizures

2015
Dexmedetomidine Dose-Dependently Attenuates Ropivacaine-Induced Seizures and Negative Emotions Via Inhibiting Phosphorylation of Amygdala Extracellular Signal-Regulated Kinase in Mice.
    Molecular neurobiology, 2016, Volume: 53, Issue:4

    Topics: Amides; Amygdala; Animals; Dexmedetomidine; Dose-Response Relationship, Drug; Emotions; Extracellular Signal-Regulated MAP Kinases; Male; Mice, Inbred C57BL; Phosphorylation; Reaction Time; Ropivacaine; Seizures

2016
Physiological and biochemical variables in captive tigers (Panthera tigris) immobilised with dexmedetomidine and ketamine or dexmedetomidine, midazolam and ketamine.
    The Veterinary record, 2015, Dec-05, Volume: 177, Issue:22

    Topics: Anesthetics, Combined; Animals; Animals, Zoo; Biochemical Phenomena; Blood Pressure; Dexmedetomidine; Female; Heart Rate; Hypnotics and Sedatives; Immobilization; Ketamine; Male; Midazolam; Seizures; Tigers

2015
Potential risk factors for dexmedetomidine withdrawal seizures in infants after surgery for congenital heart disease.
    Brain & development, 2016, Volume: 38, Issue:7

    Topics: Cardiovascular Surgical Procedures; Dexmedetomidine; Female; Fever; Heart Defects, Congenital; Humans; Hypnotics and Sedatives; Incidence; Infant; Male; Postoperative Complications; Retrospective Studies; Risk Factors; Seizures; Substance Withdrawal Syndrome

2016
Pediatric awake craniotomy for seizure focus resection with dexmedetomidine sedation-a case report.
    Journal of clinical anesthesia, 2016, Volume: 32

    Topics: Brain; Child; Conscious Sedation; Craniotomy; Dexmedetomidine; Humans; Hypnotics and Sedatives; Male; Monitoring, Intraoperative; Seizures

2016
Effect of dexmedetomidine priming on convulsion reaction induced by lidocaine.
    Medicine, 2016, Volume: 95, Issue:43

    Topics: Administration, Topical; Adrenergic alpha-2 Receptor Agonists; Anesthetics, Local; Animals; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationship, Drug; Lidocaine; Male; Rabbits; Seizures

2016
The use of continuous positive airway pressure during an awake craniotomy in a patient with obstructive sleep apnea.
    Journal of clinical anesthesia, 2008, Volume: 20, Issue:4

    Topics: Anesthesia; Continuous Positive Airway Pressure; Craniotomy; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Middle Aged; Obesity, Morbid; Seizures; Sleep Apnea, Obstructive; Temporal Lobe; Treatment Outcome

2008
[Dexmedetomidine for sedation during voice monitoring surgery in a patient with an episode of seizure].
    Masui. The Japanese journal of anesthesiology, 2008, Volume: 57, Issue:8

    Topics: Adult; Anesthesia, Local; Dexmedetomidine; Humans; Hypnotics and Sedatives; Male; Narcotics; Neuroleptanalgesia; Pentazocine; Seizures; Voice

2008
Effects of dexmedetomidine sedation on the EEG in children.
    Paediatric anaesthesia, 2009, Volume: 19, Issue:12

    Topics: Adolescent; Adrenergic alpha-Agonists; Child; Child, Preschool; Conscious Sedation; Dexmedetomidine; Electroencephalography; Female; Humans; Seizures; Signal Processing, Computer-Assisted; Sleep Stages; Treatment Outcome

2009
Dexmedetomidine controls twitch-convulsive syndrome in the course of uremic encephalopathy.
    Journal of clinical anesthesia, 2011, Volume: 23, Issue:8

    Topics: Adrenergic alpha-2 Receptor Agonists; Aged, 80 and over; Aortic Valve Stenosis; Brain Diseases; Delirium; Dexmedetomidine; Heart Valve Prosthesis Implantation; Humans; Male; Renal Dialysis; Renal Insufficiency, Chronic; Seizures; Syndrome; Time Factors; Tremor; Uremia

2011
Dexmedetomidine increases the cocaine seizure threshold in rats.
    Anesthesiology, 2002, Volume: 97, Issue:3

    Topics: Animals; Blood Pressure; Cocaine; Dexmedetomidine; Dopamine; Electroencephalography; Gas Chromatography-Mass Spectrometry; Heart Rate; Hypnotics and Sedatives; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Seizures

2002
Is attenuation of extracellular dopamine increase in the nucleus accumbens the major mechanism by which dexmedetomidine increases the cocaine seizure threshold in rats?
    Anesthesiology, 2003, Volume: 98, Issue:6

    Topics: Adrenergic alpha-Agonists; Animals; Anticonvulsants; Cocaine; Dexmedetomidine; Dopamine; Dopamine Uptake Inhibitors; Extracellular Space; Nucleus Accumbens; Rats; Seizures

2003
Dexmedetomidine decreases the convulsive potency of bupivacaine and levobupivacaine in rats: involvement of alpha2-adrenoceptor for controlling convulsions.
    Anesthesia and analgesia, 2005, Volume: 100, Issue:3

    Topics: Animals; Bupivacaine; Dexmedetomidine; Hypnotics and Sedatives; Levobupivacaine; Male; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Seizures; Yohimbine

2005
Use of dexmedetomidine in awake craniotomy in adolescents: report of two cases.
    Paediatric anaesthesia, 2006, Volume: 16, Issue:3

    Topics: Adolescent; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Brain Mapping; Brain Neoplasms; Conscious Sedation; Craniotomy; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Oligodendroglioma; Propofol; Seizures; Wakefulness

2006
Dexmedetomidine reduces seizure threshold during enflurane anaesthesia in cats.
    British journal of anaesthesia, 1999, Volume: 82, Issue:6

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Anesthetics, Inhalation; Animals; Cats; Dexmedetomidine; Dose-Response Relationship, Drug; Electroencephalography; Enflurane; Seizures; Yohimbine

1999