racemetirosine has been researched along with Seizures in 12 studies
alpha-Methyltyrosine: An inhibitor of the enzyme TYROSINE 3-MONOOXYGENASE, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with PHEOCHROMOCYTOMA. (Martindale, The Extra Pharmacopoeia, 30th ed)
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of some noradrenergic agents, phenobarbitone, diazepam and phenytoin on seizures produced by propranolol were investigated in mice." | 7.69 | Propranolol-induced seizures in mice: the role of noradrenaline. ( Amabeoku, GJ; Syce, JA, 1997) |
| "The influence of some noradrenergic, 5-hydroxytryptaminergic and cholinergic agents on imipramine-induced seizures were investigated in mice." | 7.68 | The involvement of noradrenaline, 5-hydroxytryptamine and acetylcholine in imipramine-induced seizures in mice. ( Amabeoku, GJ, 1993) |
| "The effects of some noradrenergic agents, phenobarbitone, diazepam and phenytoin on seizures produced by propranolol were investigated in mice." | 3.69 | Propranolol-induced seizures in mice: the role of noradrenaline. ( Amabeoku, GJ; Syce, JA, 1997) |
| "The influence of some noradrenergic, 5-hydroxytryptaminergic and cholinergic agents on imipramine-induced seizures were investigated in mice." | 3.68 | The involvement of noradrenaline, 5-hydroxytryptamine and acetylcholine in imipramine-induced seizures in mice. ( Amabeoku, GJ, 1993) |
| " The administration of 5-hydroxytryptophan with MK486 markedly depressed the incidence of seizures in the E1 mouse." | 3.66 | Brain monoamine levels and E1 mouse convulsions. ( Hiramatsu, M, 1981) |
| "Acute renal failure was induced by occlusion of bilateral renal arteries for 60 min, and the motor activity and brain monoamine turnover were examined 48 h later." | 1.31 | Uraemia suppresses central dopaminergic metabolism and impairs motor activity in rats. ( Adachi, N; Arai, T; Deshpande, G; Lei, B; Nagaro, T; Seyfried, FJ; Shimizu, I, 2001) |
| "Treatment with propranolol or isoproterenol did not have any effect on convulsive activity of PINX gerbils, except that isoproterenol increased the excitability of all the gerbils." | 1.28 | Noradrenergic involvement in pinealectomy induced convulsions in gerbils. ( Champney, TH, 1990) |
| "By contrast, pentylenetetrazol seizures' characteristics were significantly changed in response to the intraperitoneal administration of the norepinephrine antagonist, 6-hydroxydopamine, by abolishing the tonic and clonic phases of the seizure." | 1.27 | Differential effects of alpha-methyl-p-tyrosine and 6-hydroxydopamine on pentylenetetrazol seizures in mice. ( Abed, WT, 1986) |
| "However, the incidence of convulsions was increased by FLA-63 in rats pretreated with the catecholamine precursor L-dihydroxyphenylalanine." | 1.27 | Neuropharmacological modification of central catecholamines: effects on pinealectomy-induced convulsions. ( Blask, DE; Stockmeier, CA, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (58.33) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pericić, D | 1 |
| Svob, D | 1 |
| Hiramatsu, M | 1 |
| Tagashira, E | 1 |
| Hiramori, T | 1 |
| Nakao, K | 1 |
| Urano, T | 1 |
| Yanaura, S | 1 |
| Philo, R | 1 |
| Schonfeld, AR | 1 |
| Glick, SD | 1 |
| Amabeoku, GJ | 2 |
| Syce, JA | 1 |
| Adachi, N | 1 |
| Lei, B | 1 |
| Deshpande, G | 1 |
| Seyfried, FJ | 1 |
| Shimizu, I | 1 |
| Nagaro, T | 1 |
| Arai, T | 1 |
| Champney, TH | 1 |
| Hara, S | 1 |
| Satoh, T | 1 |
| Kitagawa, H | 1 |
| Abed, WT | 1 |
| Stockmeier, CA | 1 |
| Blask, DE | 1 |
12 other studies available for racemetirosine and Seizures
| Article | Year |
|---|---|
Interaction of stress and noradrenergic drugs in the control of picrotoxin-induced seizures.
Topics: Adrenergic Agents; Adrenergic Uptake Inhibitors; alpha-Methyltyrosine; Analysis of Variance; Animals | 2002 |
Brain monoamine levels and E1 mouse convulsions.
Topics: 5-Hydroxytryptophan; alpha-Methyltyrosine; Animals; Brain; Dioxoles; Dopamine; Evoked Potentials; Fu | 1981 |
Effects of central monoamine compounds on tranylcypromine-induced barbital-withdrawal convulsions.
Topics: alpha-Methyltyrosine; Animals; Barbital; Barbiturates; Dose-Response Relationship, Drug; Humans; Mal | 1983 |
Catecholamines and pinealectomy-induced convulsions in the gerbil (Meriones unguiculatus).
Topics: alpha-Methyltyrosine; Animals; Brain; Catecholamines; Dopamine; Gerbillinae; Levodopa; Male; Methylt | 1982 |
Neuropharmacological analysis of handling-induced seizures in gerbils.
Topics: alpha-Methyltyrosine; Amphetamine; Animals; Anticonvulsants; Apomorphine; Dopamine; Female; Gerbilli | 1980 |
The involvement of noradrenaline, 5-hydroxytryptamine and acetylcholine in imipramine-induced seizures in mice.
Topics: 5-Hydroxytryptophan; Acetylcholine; alpha-Methyltyrosine; Animals; Atropine; Clonidine; Dioxanes; Dr | 1993 |
Propranolol-induced seizures in mice: the role of noradrenaline.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic Uptake Inhibitors; alpha-Methyltyros | 1997 |
Uraemia suppresses central dopaminergic metabolism and impairs motor activity in rats.
Topics: Acute Kidney Injury; alpha-Methyltyrosine; Animals; Brain Chemistry; Coma; Confusion; Corpus Striatu | 2001 |
Noradrenergic involvement in pinealectomy induced convulsions in gerbils.
Topics: alpha-Methyltyrosine; Animals; Gerbillinae; Hypothalamus; Isoproterenol; Male; Methyltyrosines; Nore | 1990 |
Suppression of pentylenetetrazol-induced seizures by hydralazine associated with 5-hydroxytryptaminergic system in rat brain.
Topics: alpha-Methyltyrosine; Animals; Brain; Fenclonine; Hydralazine; Hydroxyindoleacetic Acid; Male; Methy | 1987 |
Differential effects of alpha-methyl-p-tyrosine and 6-hydroxydopamine on pentylenetetrazol seizures in mice.
Topics: alpha-Methyltyrosine; Animals; Brain; Catecholamines; Dopamine; Hydroxydopamines; Male; Methyltyrosi | 1986 |
Neuropharmacological modification of central catecholamines: effects on pinealectomy-induced convulsions.
Topics: alpha-Methyltyrosine; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain; Catechol | 1986 |