Compounds > pyridine-4-aldoxime
Page last updated: 2024-11-05

pyridine-4-aldoxime

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

pyridine-4-aldoxime: RN given for cpd without isomeric designation [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID135460230
MeSH IDM0144339

Synonyms (33)

Synonym
nsc 63847
ccris 7744
pyridine, 4-formyl-, oxime
isonicotinaldoxime
einecs 211-796-6
4-pyridine aldoxime
isonicotinaldehyde, oxime
pyridine-4-aldoxime
4-(hydroxyiminomethyl)pyridine
wln: t6nj c1unq
nsc-63847
nsc63847
4-pyridinecarboxaldehyde, oxime
4-pyridinealdoxime, 98%
4-(nitrosomethylidene)-1h-pyridine
A836584
AKOS016050385
Q-101280
4-pyridinecarboxaldehyde, oxime, (e)-
isonicotinaldehyde oxime #
OFYLBLSSPQTTHT-VMPITWQZSA-N
1637-52-1
(e)-4-pyridinecarbaldehyde oxime
pyridine-4-carboxaldoxime
GS-5936
(e)-isonicotinaldehyde oxime
(ne)-n-(pyridin-4-ylmethylidene)hydroxylamine
AMY40496
DTXSID80896842
(z)-n-[(pyridin-4-yl)methylidene]hydroxylamine
CS-0157397
n-[(pyridin-4-yl)methylidene]hydroxylamine
(e)-isonicotinaldehydeoxime

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" The dose-response effects of 4-PA alone were also examined."( Effects of 4-pyridine aldoxime on nerve agent-inhibited acetylcholinesterase activity in guinea pigs.
McDonough, JH; Shih, TM; Skovira, JW, 2009)		0.35
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
sarin
Sarin: An organophosphorus ester compound that produces potent and irreversible inhibition of cholinesterase. It is toxic to the nervous system and is a chemical warfare agent.. isopropyl methylphosphonofluoridate : A phosphinic ester that is the isopropyl ester of methylphosphonofluoridic acid.. sarin : A racemate composed of equal amounts of (R)- and (S)-sarin. A potent and irreversible inhibitor of acetylcholinesterase that is toxic to the nervous system and is employed as a chemical warfare agent.		2.0510fluorine molecular entity;
phosphinic ester
obidoxime chloride
Obidoxime Chloride: Cholinesterase reactivator occurring in two interchangeable isomeric forms, syn and anti.		2.7230
paraoxon
[no description available]		2.110aryl dialkyl phosphate;
organophosphate insecticide		EC 3.1.1.7 (acetylcholinesterase) inhibitor;
mouse metabolite
benthiocarb
Saturn: The sixth planet in order from the sun. It is one of the five outer planets of the solar system. Its twelve natural satellites include Phoebe and Titan.		1.9710monochlorobenzenes;
monothiocarbamic ester
vx
VX nerve agent : A organic thiophosphate that is the ethyl ester of S-{2-[di(propan-2-yl)amino]ethyl} O hydrogen methylphosphonothioate. A toxic nerve agent used in chemical warfare.		2.520organic thiophosphate;
tertiary amino compound		EC 3.1.1.7 (acetylcholinesterase) inhibitor;
neurotoxin
cyclohexyl methylphosphonofluoridate
cyclohexyl methylphosphonofluoridate: acetylcholinesterase inhibitor		2.0510
cysteine
Cysteine: A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.. L-cysteinium : The L-enantiomer of cysteinium.. cysteine : A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3.		1.9710cysteiniumfundamental metabolite
pralidoxime
pralidoxime: RN given refers to parent cpd; chloride was minor descriptor (75-80); on-line & Index Medicus search PRALIDOXIME COMPOUNDS (66-80). pralidoxime : A pyridinium ion that is 1-methylpyridinium substituted by a (hydroxyimino)methyl group at position 2.		2.2110pyridinium ionantidote to organophosphate poisoning;
antidote to sarin poisoning;
cholinergic drug;
cholinesterase reactivator
pyridine-2-aldoxime
pyridine-2-aldoxime: RN given refers to parent cpd		1.9710
ConditionIndicatedRelationship StrengthStudiesTrials
Encephalopathy, Toxic
[description not available]		02.0510
Absence Seizure
[description not available]		02.0510
Seizures
Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.		02.0510