proglumide has been researched along with Seizures in 4 studies
Proglumide: A drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.
proglumide : A racemate composed of equal amounts of (R)- and (S)-proglumide. A non-selective CCK antagonist that was used primarily for treatment of stomach ulcers, but has been replaced by newer drugs.
N(2)-benzoyl-N,N-dipropyl-alpha-glutamine : A dicarboxylic acid monoamide obtained by formal condensation of the alpha-carboxy group of N-benzoylglutamic acid with dippropylamine.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Subcutaneous administration of caerulein (100-500 micrograms/kg) significantly reduced the development of picrotoxin (8 mg/kg) seizures in male mice." | 3.67 | [Modulating effect of cerulein on benzodiazepine receptors]. ( Maĭmets, MO; Nurk, AM; Riago, LK; Soosaar, AKh; Vasar, EE, 1985) |
| "Proglumide pretreatment did not alter any of these effects of brief footshock stress paradigm." | 1.32 | Differential contribution of cholecystokinin receptors to stress-induced modulation of seizure and nociception thresholds in mice. ( Dehpour, AR; Homayoun, H, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahmad, M | 1 |
| Abu-Taweel, GM | 1 |
| Aboshaiqah, AE | 1 |
| Ajarem, JS | 1 |
| Homayoun, H | 1 |
| Dehpour, AR | 1 |
| Vasar, EE | 1 |
| Riago, LK | 1 |
| Soosaar, AKh | 1 |
| Nurk, AM | 1 |
| Maĭmets, MO | 1 |
| Panerai, AE | 1 |
| Rovati, LC | 1 |
| Bianchi, M | 1 |
| Bareggi, SR | 1 |
| Mantegazza, P | 1 |
4 other studies available for proglumide and Seizures
| Article | Year |
|---|---|
The effects of quinacrine, proglumide, and pentoxifylline on seizure activity, cognitive deficit, and oxidative stress in rat lithium-pilocarpine model of status epilepticus.
Topics: Animals; Cognition Disorders; Lithium Compounds; Male; Oxidative Stress; Pentoxifylline; Pilocarpine | 2014 |
Differential contribution of cholecystokinin receptors to stress-induced modulation of seizure and nociception thresholds in mice.
Topics: Animals; Dose-Response Relationship, Drug; Male; Mice; Pain Measurement; Pain Threshold; Proglumide; | 2004 |
[Modulating effect of cerulein on benzodiazepine receptors].
Topics: Animals; Brain; Ceruletide; Dose-Response Relationship, Drug; Drug Interactions; Flunitrazepam; Male | 1985 |
Effect of a cholecystokinin antagonist on some effects of diazepam.
Topics: Animals; Cholecystokinin; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Glutamine; Mal | 1987 |