| Substance | Description | Relationhip Strength | Studies | Trials | Classes | Roles |
|---|
| 2,4-methanoglutamate | [no description available] | medium | 2 | 0 | | |
| aspartic acid | [no description available] | medium | 1 | 0 | aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid | Escherichia coli metabolite;
mouse metabolite;
neurotransmitter |
| n-methylaspartate | [no description available] | medium | 7 | 0 | amino dicarboxylic acid;
D-alpha-amino acid;
D-aspartic acid derivative;
secondary amino compound | neurotransmitter agent |
| glutamic acid | [no description available] | medium | 3 | 0 | glutamic acid;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid | Escherichia coli metabolite;
ferroptosis inducer;
micronutrient;
mouse metabolite;
neurotransmitter;
nutraceutical |
| glycine | [no description available] | medium | 14 | 0 | alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid | EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical |
| clozapine | [no description available] | medium | 1 | 0 | benzodiazepine;
N-arylpiperazine;
N-methylpiperazine;
organochlorine compound | adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
environmental contaminant;
GABA antagonist;
histamine antagonist;
muscarinic antagonist;
second generation antipsychotic;
serotonergic antagonist;
xenobiotic |
| haloperidol | [no description available] | medium | 1 | 0 | aromatic ketone;
hydroxypiperidine;
monochlorobenzenes;
organofluorine compound;
tertiary alcohol | antidyskinesia agent;
antiemetic;
dopaminergic antagonist;
first generation antipsychotic;
serotonergic antagonist |
| kainic acid | [no description available] | medium | 2 | 0 | dicarboxylic acid;
L-proline derivative;
non-proteinogenic L-alpha-amino acid;
pyrrolidinecarboxylic acid | antinematodal drug;
excitatory amino acid agonist |
| dizocilpine maleate | [no description available] | medium | 5 | 0 | maleate salt;
tetracyclic antidepressant | anaesthetic;
anticonvulsant;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist |
| alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid | [no description available] | medium | 2 | 0 | non-proteinogenic alpha-amino acid | |
| 6-cyano-7-nitroquinoxaline-2,3-dione | [no description available] | medium | 1 | 0 | quinoxaline derivative | |
| quisqualic acid | [no description available] | medium | 1 | 0 | non-proteinogenic alpha-amino acid | |
| gamma-aminobutyric acid | [no description available] | medium | 2 | 0 | amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid | human metabolite;
neurotransmitter;
Saccharomyces cerevisiae metabolite;
signalling molecule |
| selfotel | [no description available] | medium | 3 | 0 | non-proteinogenic alpha-amino acid | |
| 2-amino-5-phosphonovalerate | [no description available] | medium | 1 | 0 | non-proteinogenic alpha-amino acid | NMDA receptor antagonist |
| fura-2 | [no description available] | medium | 1 | 0 | | |
| kynurenic acid | [no description available] | medium | 1 | 0 | monohydroxyquinoline;
quinolinemonocarboxylic acid | G-protein-coupled receptor agonist;
human metabolite;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist;
Saccharomyces cerevisiae metabolite |
| 5,7-dichlorokynurenic acid | [no description available] | medium | 1 | 0 | quinolines | |
| bicuculline methiodide | [no description available] | medium | 1 | 0 | | |
| ng-nitroarginine methyl ester | [no description available] | medium | 1 | 0 | alpha-amino acid ester;
L-arginine derivative;
methyl ester;
N-nitro compound | EC 1.14.13.39 (nitric oxide synthase) inhibitor |
| bicuculline | [no description available] | medium | 1 | 0 | benzylisoquinoline alkaloid;
isoquinoline alkaloid;
isoquinolines | agrochemical;
central nervous system stimulant;
GABA-gated chloride channel antagonist;
GABAA receptor antagonist;
neurotoxin |
| morphine | [no description available] | medium | 1 | 0 | morphinane alkaloid;
organic heteropentacyclic compound;
tertiary amino compound | anaesthetic;
drug allergen;
environmental contaminant;
geroprotector;
mu-opioid receptor agonist;
opioid analgesic;
plant metabolite;
vasodilator agent;
xenobiotic |
| capsaicin | [no description available] | medium | 1 | 0 | capsaicinoid | non-narcotic analgesic;
TRPV1 agonist;
voltage-gated sodium channel blocker |
| phosphoserine | [no description available] | medium | 1 | 0 | non-proteinogenic alpha-amino acid;
O-phosphoamino acid;
serine derivative | human metabolite |
| 1-amino-1,3-dicarboxycyclopentane | [no description available] | medium | 1 | 0 | | |
| isospaglumic acid | [no description available] | medium | 1 | 0 | dipeptide | human metabolite |
| cycloleucine | [no description available] | medium | 1 | 0 | non-proteinogenic alpha-amino acid | EC 2.5.1.6 (methionine adenosyltransferase) inhibitor |
| alanine | [no description available] | medium | 1 | 0 | alanine zwitterion;
alanine;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid | EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor;
fundamental metabolite |
| 4-carboxy-3-hydroxyphenylglycine | [no description available] | medium | 1 | 0 | hydroxybenzoic acid | |
| 2-(2,3-dicarboxycyclopropyl)glycine | [no description available] | medium | 1 | 0 | | |
| glutamine | [no description available] | medium | 1 | 0 | amino acid zwitterion;
glutamine family amino acid;
glutamine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid | EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite |
| 3-chloroalanine | [no description available] | low | 0 | 0 | chloroalanine;
non-proteinogenic alpha-amino acid;
organochlorine compound | |
| 2-amino-3-ketobutyrate | [no description available] | low | 0 | 0 | 3-oxo monocarboxylic acid;
non-proteinogenic alpha-amino acid | |
| 2,3-diaminopropionic acid | [no description available] | low | 0 | 0 | alanine derivative;
amino acid zwitterion;
beta-amino acid;
diamino acid;
non-proteinogenic alpha-amino acid | Escherichia coli metabolite |
| 2-aminoadipic acid | [no description available] | low | 0 | 0 | amino dicarboxylic acid;
dicarboxylic fatty acid;
non-proteinogenic alpha-amino acid | Caenorhabditis elegans metabolite;
mammalian metabolite |
| 2,4-diaminobutyric acid | [no description available] | low | 0 | 0 | diamino acid;
gamma-amino acid;
non-proteinogenic alpha-amino acid | |
| 1-aminocyclopropane-1-carboxylic acid | [no description available] | low | 0 | 0 | amino acid zwitterion;
monocarboxylic acid;
non-proteinogenic alpha-amino acid | ethylene releasers;
plant metabolite |
| dihydroxyphenylalanine | [no description available] | low | 0 | 0 | hydroxyphenylalanine;
non-proteinogenic alpha-amino acid;
tyrosine derivative | human metabolite |
| kynurenine | [no description available] | low | 0 | 0 | aromatic ketone;
non-proteinogenic alpha-amino acid;
substituted aniline | human metabolite |
| thyroxine | [no description available] | low | 0 | 0 | 2-halophenol;
amino acid zwitterion;
iodophenol;
iodothyronine;
non-proteinogenic alpha-amino acid;
tyrosine derivative | mitogen |
| ibotenic acid | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | neurotoxin |
| homarine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | |
| 2-amino-3-phosphonopropionic acid | [no description available] | low | 0 | 0 | alanine derivative;
non-proteinogenic alpha-amino acid;
phosphonic acids | human metabolite;
metabotropic glutamate receptor antagonist |
| 2-phenylglycine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | human metabolite |
| p-fluorophenylalanine | [no description available] | low | 0 | 0 | fluoroamino acid;
monofluorobenzenes;
non-proteinogenic alpha-amino acid;
phenylalanine derivative | |
| penicillamine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid;
thiol | |
| penicillamine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid;
penicillamine | antirheumatic drug;
chelator;
copper chelator;
drug allergen |
| iminodiacetic acid | [no description available] | low | 0 | 0 | amino dicarboxylic acid;
glycine derivative;
non-proteinogenic alpha-amino acid | chelator |
| 2-fluorophenylalanine | [no description available] | low | 0 | 0 | monofluorobenzenes;
non-proteinogenic alpha-amino acid;
phenylalanine derivative | |
| 5-fluorotryptophan | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid;
organofluorine compound;
tryptophan derivative | |
| thiazolidine-4-carboxylic acid | [no description available] | low | 0 | 0 | alpha-amino acid zwitterion;
non-proteinogenic alpha-amino acid;
sulfur-containing amino acid;
thiazolidinemonocarboxylic acid | antidote;
antioxidant;
hepatoprotective agent |
| 3-cyanoalanine | [no description available] | low | 0 | 0 | alanine derivative;
aliphatic nitrile;
non-proteinogenic alpha-amino acid | |
| methionine sulfoximine | [no description available] | low | 0 | 0 | methionine derivative;
non-proteinogenic alpha-amino acid;
sulfoximide | |
| buthionine sulfoximine | [no description available] | low | 0 | 0 | diastereoisomeric mixture;
homocysteines;
non-proteinogenic alpha-amino acid;
sulfoximide | EC 6.3.2.2 (glutamate--cysteine ligase) inhibitor;
ferroptosis inducer |
| cysteic acid | [no description available] | low | 0 | 0 | alanine derivative;
amino sulfonic acid;
carboxyalkanesulfonic acid;
cysteine derivative;
non-proteinogenic alpha-amino acid | animal metabolite |
| cilazaprilat | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | |
| 3-hydroxynorvaline | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid;
non-proteinogenic amino acid derivative | |
| sinefungin | [no description available] | low | 0 | 0 | adenosines;
non-proteinogenic alpha-amino acid | antifungal agent;
antimicrobial agent |
| n-phenylglycine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | allergen |
| 2-(methylamino)isobutyric acid | [no description available] | low | 0 | 0 | alanine derivative;
alpha-amino acid zwitterion;
non-proteinogenic alpha-amino acid;
secondary amino compound | human urinary metabolite |
| 2-tyrosine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid;
phenols;
phenylalanine derivative | |
| 3-fluorotyrosine | [no description available] | low | 0 | 0 | fluoroamino acid;
fluorophenol;
non-proteinogenic alpha-amino acid;
tyrosine derivative | |
| triazolealanine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid;
triazoles | |
| 5-methyltryptophan | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid;
tryptophan derivative | |
| 4-methyleneglutamic acid | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | |
| 1-methyltryptophan | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid;
tryptophan derivative | antineoplastic agent;
EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor |
| alpha-aminopimelic acid | [no description available] | low | 0 | 0 | amino dicarboxylic acid;
non-proteinogenic alpha-amino acid | bacterial metabolite |
| lanthionine | [no description available] | low | 0 | 0 | alanine derivative;
non-proteinogenic alpha-amino acid;
organic sulfide | bacterial metabolite |
| 6-hydroxydopa | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | |
| dityrosine | [no description available] | low | 0 | 0 | biphenyls;
non-proteinogenic alpha-amino acid;
tyrosine derivative | biomarker |
| selenomethylselenocysteine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid;
selenocysteines | antineoplastic agent;
human metabolite |
| dehydroalanine | [no description available] | low | 0 | 0 | 2,3-dehydroamino acid;
alpha,beta-unsaturated monocarboxylic acid;
amino acid zwitterion;
enamine;
non-proteinogenic alpha-amino acid | alkylating agent;
human metabolite;
mouse metabolite |
| delta-n-hydroxyornithine | [no description available] | low | 0 | 0 | amino acid zwitterion;
hydroxylamines;
L-ornithine derivative;
non-proteinogenic alpha-amino acid | |
| melagatran | [no description available] | low | 0 | 0 | azetidines;
carboxamidine;
dicarboxylic acid monoamide;
non-proteinogenic alpha-amino acid;
secondary amino compound | anticoagulant;
EC 3.4.21.5 (thrombin) inhibitor;
serine protease inhibitor |
| 3-nitrotyrosine | [no description available] | low | 0 | 0 | 2-nitrophenols;
C-nitro compound;
nitrotyrosine;
non-proteinogenic alpha-amino acid | |
| 5',5',5'-trifluoroleucine | [no description available] | low | 0 | 0 | leucine derivative;
non-proteinogenic alpha-amino acid;
organofluorine compound | |
| azaleucine | [no description available] | low | 0 | 0 | alanine derivative;
leucine derivative;
non-proteinogenic alpha-amino acid;
tertiary amino compound | |
| 2-amino-3,3-dimethylbutanoic acid | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | metabolite |
| cucumopine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | |
| cucurbitine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | |
| temocaprilat | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | |
| alpha-methyl-4-carboxyphenylglycine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | metabotropic glutamate receptor antagonist |
| serine ethanolamine phosphate | [no description available] | low | 0 | 0 | amino acid zwitterion;
non-proteinogenic alpha-amino acid;
O-phosphoamino acid;
phosphoethanolamine;
serine derivative | |
| indicaxanthin | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | |
| thermozymocidin | [no description available] | low | 0 | 0 | alpha-amino fatty acid;
hydroxy monocarboxylic acid;
non-proteinogenic alpha-amino acid;
sphingoid | antifungal agent;
antimicrobial agent;
antineoplastic agent;
apoptosis inducer;
EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor;
fungal metabolite;
immunosuppressive agent |
| argpyrimidine | [no description available] | low | 0 | 0 | hydroxypyrimidine;
L-arginine derivative;
non-proteinogenic alpha-amino acid | epitope |
| brasilicardin a | [no description available] | low | 0 | 0 | benzoate ester;
carbotricyclic compound;
diterpenoid;
N-acetyl-D-glucosaminide;
non-proteinogenic alpha-amino acid;
phenols | antimicrobial agent;
antineoplastic agent;
bacterial metabolite;
immunosuppressive agent |
| 4-formylaminooxyvinylglycine | [no description available] | low | 0 | 0 | non-proteinogenic alpha-amino acid | metabolite |