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biperiden and Seizures

biperiden has been researched along with Seizures in 10 studies

Biperiden: A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapyramidal symptoms induced by phenothiazine derivatives and reserpine.
biperiden : A member of the class of piperidines that is N-propylpiperidine in which the methyl hydrogens have been replaced by hydroxy, phenyl, and 5-norbornen-2-yl groups. A muscarinic antagonist affecting both the central and peripheral nervous systems, it is used in the treatment of all forms of Parkinson's disease.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"The ability of the nerve agents tabun, sarin, soman, GF, VR, and VX to produce brain seizures and the effectiveness of the anticholinergics biperiden HCl or atropine SO4 as an anticonvulsant treatment were studied in a guinea-pig model."3.70Efficacy of biperiden and atropine as anticonvulsant treatment for organophosphorus nerve agent intoxication. ( McDonough, JH; Shih, TM, 2000)
"The effects of anticonvulsant drugs on convulsions were also evaluated."1.33Scopolamine-induced convulsions in fasted mice after food intake: effects of glucose intake, antimuscarinic activity and anticonvulsant drugs. ( Açikmeşe, B; Celik, PY; Enginar, N; Nurten, A, 2005)
"Biperiden is an anticholinergic compound that has demonstrated effectiveness for treating organophosphate-induced seizure/convulsions."1.32Pharmacokinetics of intramuscularly administered biperiden in guinea pigs challenged with soman. ( Byers, CE; Capacio, BR; Caro, ST; McDonough, JH, 2003)
"Budipine is a novel antiparkinsonian drug which is particularly beneficial in the treatment of parkinsonian tremor."1.29Effects of the antiparkinsonian drug budipine on central neurotransmitter systems. ( Klockgether, T; Löschmann, PA; Petersen, V; Steinbach, JP; Turski, L; Wüllner, U, 1996)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19906 (60.00)18.7374
1990's1 (10.00)18.2507
2000's3 (30.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Capacio, BR1
Byers, CE1
Caro, ST1
McDonough, JH2
Enginar, N1
Nurten, A1
Celik, PY1
Açikmeşe, B1
Ito, T1
Hori, M1
Yoshida, K1
Shimizu, M1
Klockgether, T1
Wüllner, U1
Steinbach, JP1
Petersen, V1
Turski, L1
Löschmann, PA1
Shih, TM1
Tan, U1
Huffmann, G1
Nelson, RB1
North, DS1
Kaneriya, M1
Fletcher, CV1
Boissier, JR1
Simon, P1
Villeneuve, A1
Larousse, C1
Ayd, FJ1

Reviews

1 review available for biperiden and Seizures

ArticleYear
Side effects of depot fluphenazines.
    Advances in biochemical psychopharmacology, 1974, Volume: 9, Issue:0

    Topics: Agranulocytosis; Barbiturates; Basal Ganglia Diseases; Benztropine; Biperiden; Delayed-Action Prepar

1974

Other Studies

9 other studies available for biperiden and Seizures

ArticleYear
Pharmacokinetics of intramuscularly administered biperiden in guinea pigs challenged with soman.
    Drug and chemical toxicology, 2003, Volume: 26, Issue:1

    Topics: Animals; Biperiden; Cholinesterase Inhibitors; Electroencephalography; Gas Chromatography-Mass Spect

2003
Scopolamine-induced convulsions in fasted mice after food intake: effects of glucose intake, antimuscarinic activity and anticonvulsant drugs.
    Neuropharmacology, 2005, Volume: 49, Issue:3

    Topics: Animals; Anticonvulsants; Biperiden; Eating; Glucose; Hypoglycemia; Male; Mice; Mice, Inbred BALB C;

2005
Facilitation of tungstic acid gel-induced cortical epilepsy in rats by depression of the reticular formation.
    Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 245, Issue:2

    Topics: Acids; Animals; Anticonvulsants; Biperiden; Chlorpromazine; Convulsants; Decerebrate State; Drug Int

1980
Effects of the antiparkinsonian drug budipine on central neurotransmitter systems.
    European journal of pharmacology, 1996, Apr-22, Volume: 301, Issue:1-3

    Topics: Animals; Antiparkinson Agents; Biperiden; Central Nervous System; Dopamine; Excitatory Amino Acid An

1996
Efficacy of biperiden and atropine as anticonvulsant treatment for organophosphorus nerve agent intoxication.
    Archives of toxicology, 2000, Volume: 74, Issue:3

    Topics: Animals; Anticonvulsants; Atropine; Biperiden; Cholinesterase Inhibitors; Cholinesterase Reactivator

2000
Electrocorticographic changes induced by topically applied succinylcholine and biperiden.
    Electroencephalography and clinical neurophysiology, 1977, Volume: 42, Issue:2

    Topics: Acoustic Stimulation; Animals; Biperiden; Cats; Cerebral Cortex; Drug Interactions; Electroencephalo

1977
[Akineton delir and other emergencies caused by psychopharmaca].
    Deutsche medizinische Wochenschrift (1946), 1978, May-26, Volume: 103, Issue:21

    Topics: Adult; Age Factors; Alcohol Withdrawal Delirium; Basal Ganglia Diseases; Biperiden; Diagnosis, Diffe

1978
The influence of biperiden, benztropine, physostigmine and diazepam on the convulsive effects of Cicuta douglasii.
    Proceedings of the Western Pharmacology Society, 1978, Volume: 21

    Topics: Animals; Benztropine; Biperiden; Cholinesterase Inhibitors; Diazepam; Dose-Response Relationship, Dr

1978
Flurothyl in mice: seizure, post-convulsive behavior, and interactions with psychotropic drugs.
    Canadian journal of physiology and pharmacology, 1968, Volume: 46, Issue:1

    Topics: Amphetamine; Animals; Atropine; Behavior, Animal; Biperiden; Caffeine; Catalepsy; Central Nervous Sy

1968