Page last updated: 2024-10-28

glyburide and Seizures

glyburide has been researched along with Seizures in 16 studies

Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
" In this study, we investigated the possible beneficial effects of lasmiditan and sumatriptan against post-stroke seizures in mice and explored underlying mechanisms in their effects."8.12Neuroprotective effects of Lasmiditan and Sumatriptan in an experimental model of post-stroke seizure in mice: Higher effects with concurrent opioid receptors or K ( Amanlou, A; Dehpour, AR; Ejtemaei-Mehr, S; Eslami, F; Ghasemi, M; Rahimi, N; Rashidian, A; Shayan, M; Solaimanian, S, 2022)
"Our data revealed that seizure threshold was increased 6 to 72 hours after nasal obstruction, reaching a peak 48 hours afterward, compared with either control or sham-operated mice (P<0."5.35Mouth breathing increases the pentylenetetrazole-induced seizure threshold in mice: a role for ATP-sensitive potassium channels. ( Dehpour, AR; Fakhimi, A; Ghasemi, M; Niaki, SE; Shafaroodi, H; Shakiba, B, 2008)
" In this study, we investigated the possible beneficial effects of lasmiditan and sumatriptan against post-stroke seizures in mice and explored underlying mechanisms in their effects."4.12Neuroprotective effects of Lasmiditan and Sumatriptan in an experimental model of post-stroke seizure in mice: Higher effects with concurrent opioid receptors or K ( Amanlou, A; Dehpour, AR; Ejtemaei-Mehr, S; Eslami, F; Ghasemi, M; Rahimi, N; Rashidian, A; Shayan, M; Solaimanian, S, 2022)
" This study was conducted to investigate whether or not triamterene, a K(+)-sparing diuretic, can generate protection against seizures induced by intravenous or intraperitoneal pentylenetetrazole (PTZ) models."3.83A role for ATP-sensitive potassium channels in the anticonvulsant effects of triamterene in mice. ( Almasirad, A; Barati, S; Ghasemi, M; Moezi, L; Shafaroodi, H, 2016)
"Diabetes can exacerbate seizures and worsen seizure-related brain damage."1.39Pregabalin attenuates excitotoxicity in diabetes. ( Cheng, JT; Huang, CC; Huang, CW; Lai, MC; Tsai, JJ; Wu, SN, 2013)
"Our data revealed that seizure threshold was increased 6 to 72 hours after nasal obstruction, reaching a peak 48 hours afterward, compared with either control or sham-operated mice (P<0."1.35Mouth breathing increases the pentylenetetrazole-induced seizure threshold in mice: a role for ATP-sensitive potassium channels. ( Dehpour, AR; Fakhimi, A; Ghasemi, M; Niaki, SE; Shafaroodi, H; Shakiba, B, 2008)
"Glipizide is a new hypoglycaemic sulphonylurea."1.25[Experimental study of glipizide. A comparison with other hypoglycemic sulfonamides (author's transl)]. ( Alric, R; Loubatières, AL; Loubatieres-Mariani, MM; Ribes, G; Sorial, G; Tarasco, A, 1975)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19903 (18.75)18.7374
1990's2 (12.50)18.2507
2000's4 (25.00)29.6817
2010's6 (37.50)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Shingalapur, RV1
Hosamani, KM1
Keri, RS1
Hugar, MH1
Shayan, M1
Eslami, F1
Amanlou, A1
Solaimanian, S1
Rahimi, N1
Rashidian, A1
Ejtemaei-Mehr, S1
Ghasemi, M5
Dehpour, AR5
Ostadhadi, S1
Moradi, A1
Zolfaghari, S1
Nikoui, V1
Huang, CW1
Lai, MC1
Cheng, JT1
Tsai, JJ1
Huang, CC1
Wu, SN1
Socała, K1
Nieoczym, D1
Pieróg, M1
Wlaź, P1
Shafaroodi, H4
Barati, S1
Almasirad, A1
Moezi, L1
Niaki, SE1
Shakiba, B1
Fakhimi, A1
Lim, CC1
Gan, R1
Chan, CL1
Tan, AW1
Khoo, JJ1
Chia, SY1
Kao, SL1
Abisheganaden, J1
Sitoh, YY1
Karimollah, AR1
Gholipour, T1
Nezami, BG1
Ebrahimi, F2
Araníbar, H1
Cerda, M1
Asadi, S1
Sadeghipour, H1
Tavakoli, S1
Hajrasouliha, AR1
Pavone, L1
Mollica, F1
Musumeci, S1
Marino, S1
Pampiglione, G1
Loubatières, AL1
Loubatieres-Mariani, MM1
Alric, R1
Ribes, G1
Sorial, G1
Tarasco, A1
Fanego, L1
Crumley, L1
Edelson, GW1
Bar-Oz, B1
Amitai, Y1
Epishin, AV1
Likhatskaia, VA1
Iakimishina, MM1
Baranenko, LP1

Other Studies

16 other studies available for glyburide and Seizures

ArticleYear
Derivatives of benzimidazole pharmacophore: synthesis, anticonvulsant, antidiabetic and DNA cleavage studies.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:5

    Topics: Animals; Anticonvulsants; Benzimidazoles; Diabetes Mellitus, Experimental; DNA Cleavage; DNA, Bacter

2010
Neuroprotective effects of Lasmiditan and Sumatriptan in an experimental model of post-stroke seizure in mice: Higher effects with concurrent opioid receptors or K
    Toxicology and applied pharmacology, 2022, 11-01, Volume: 454

    Topics: Adenosine Triphosphate; Animals; Anticonvulsants; bcl-2-Associated X Protein; Benzamides; Disease Mo

2022
Cromakalim, a Potassium Channel Opener, Ameliorates the Organophosphate and Carbamate-Induced Seizure in Mice.
    Acta medica Iranica, 2018, Volume: 56, Issue:1

    Topics: Animals; Anticonvulsants; Carbamates; Cromakalim; Dichlorvos; Dose-Response Relationship, Drug; Glyb

2018
Pregabalin attenuates excitotoxicity in diabetes.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Adenosine Triphosphate; Animals; Anticonvulsants; Blood Glucose; Cell Line; Diabetic Neuropathies; D

2013
Role of the adenosine system and glucose restriction in the acute anticonvulsant effect of caprylic acid in the 6 Hz psychomotor seizure test in mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2015, Mar-03, Volume: 57

    Topics: 3-Hydroxybutyric Acid; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonis

2015
A role for ATP-sensitive potassium channels in the anticonvulsant effects of triamterene in mice.
    Epilepsy research, 2016, Volume: 121

    Topics: Analysis of Variance; Animals; Anticonvulsants; Convulsants; Diazoxide; Disease Models, Animal; Dose

2016
Mouth breathing increases the pentylenetetrazole-induced seizure threshold in mice: a role for ATP-sensitive potassium channels.
    Epilepsy & behavior : E&B, 2008, Volume: 13, Issue:2

    Topics: Acid-Base Equilibrium; Acidosis, Respiratory; Animals; Brain; Carbon Dioxide; Diazoxide; Dose-Respon

2008
Severe hypoglycemia associated with an illegal sexual enhancement product adulterated with glibenclamide: MR imaging findings.
    Radiology, 2009, Volume: 250, Issue:1

    Topics: Adult; Aged; Blood Volume; Brain; Cerebrovascular Disorders; Coma; Consciousness Disorders; Diffusio

2009
ATP-sensitive potassium channels contribute to the time-dependent alteration in the pentylenetetrazole-induced seizure threshold in diabetic mice.
    Seizure, 2010, Volume: 19, Issue:1

    Topics: Analysis of Variance; Animals; Blood Glucose; Body Weight; Cromakalim; Diabetes Mellitus, Experiment

2010
Hypoglycemic seizure in Munchausen-by-proxy syndrome.
    Pediatric emergency care, 2005, Volume: 21, Issue:6

    Topics: Diagnosis, Differential; Glucose; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; Infant; Male

2005
Role of ATP-sensitive potassium channels in the biphasic effects of morphine on pentylenetetrazole-induced seizure threshold in mice.
    Epilepsy research, 2007, Volume: 75, Issue:1

    Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Blood Glucose; Cromakalim; Disease Models, Animal

2007
Accidental glibenclamide ingestion in an infant: clinical and electroencephalographic aspects.
    Developmental medicine and child neurology, 1980, Volume: 22, Issue:3

    Topics: Cerebral Cortex; Electroencephalography; Evoked Potentials; Female; Glyburide; Humans; Hypoglycemia;

1980
[Experimental study of glipizide. A comparison with other hypoglycemic sulfonamides (author's transl)].
    Diabete & metabolisme, 1975, Volume: 1

    Topics: Administration, Oral; Ammonia; Animals; Dogs; Dose-Response Relationship, Drug; Female; Glipizide; G

1975
Seizure in a polypharmacy household.
    Hospital practice (Office ed.), 1992, Oct-15, Volume: 27, Issue:10

    Topics: Aged; Dementia; Diagnosis, Differential; Female; Glyburide; Humans; Hypoglycemia; Seizures; Self Med

1992
[Overdosage of glibenclamide presenting with lethargy and seizures in a child].
    Harefuah, 1992, Volume: 123, Issue:5-6

    Topics: Drug Overdose; Female; Glyburide; Humans; Hypoglycemia; Infant; Seizures; Sleep Stages; Time Factors

1992
[A case of hypoglycemia with a marked convulsive syndrome after intake of maninil].
    Vrachebnoe delo, 1988, Issue:5

    Topics: Aged; Diabetes Mellitus; Female; Glyburide; Humans; Hypoglycemia; Seizures

1988