Page last updated: 2024-10-18

glutaric acid and Seizures

glutaric acid has been researched along with Seizures in 9 studies

glutaric acid: RN given refers to parent cpd
glutaric acid : An alpha,omega-dicarboxylic acid that is a linear five-carbon dicarboxylic acid.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"Glutaric acidemia type I (GA-I) is an inherited metabolic disease characterized by accumulation of glutaric acid (GA) and seizures."7.78m-Trifluoromethyl diphenyl diselenide attenuates glutaric acid-induced seizures and oxidative stress in rat pups: involvement of the γ-aminobutyric acidergic system. ( Brüning, CA; Fighera, MR; Gai, BM; Magni, DV; Nogueira, CW; Quines, CB; Rosa, SG, 2012)
"Glutaric acidaemia type I (GA-I) is a cerebral organic disorder characterized by the accumulation of glutaric acid (GA) and seizures."3.96The role of nitric oxide in glutaric acid-induced convulsive behavior in pup rats. ( Bortolatto, CF; Brüning, CA; Magni, DV; Nogueira, CW; Nonemacher, NT; Quines, CB; Rosa, SG, 2020)
"Glutaric acidemia type I (GA-I) is an inherited metabolic disease characterized by accumulation of glutaric acid (GA) and seizures."3.78m-Trifluoromethyl diphenyl diselenide attenuates glutaric acid-induced seizures and oxidative stress in rat pups: involvement of the γ-aminobutyric acidergic system. ( Brüning, CA; Fighera, MR; Gai, BM; Magni, DV; Nogueira, CW; Quines, CB; Rosa, SG, 2012)
"Glutaric acidemia type I (GA-I) is an inherited metabolic disease characterized by accumulation of glutaric acid (GA) and seizures."3.77Lipopolysaccharide enhances glutaric acid-induced seizure susceptibility in rat pups: behavioral and electroencephalographic approach. ( Ferreira, J; Fighera, MR; Furian, AF; Magni, DV; Mello, CF; Oliveira, AP; Oliveira, MS; Royes, LF; Santos, AR; Souza, MA, 2011)
"Glutaric acidemia type I (GA-I) is an inherited metabolic disease characterized by striatal degeneration, seizures, and accumulation of glutaric acid (GA)."3.74Creatine decreases convulsions and neurochemical alterations induced by glutaric acid in rats. ( Ferreira, J; Fighera, MR; Fiorenza, NG; Furian, AF; Magni, DV; Mello, CF; Oliveira, MS; Royes, LF, 2007)
"Her symptoms consisted of a few convulsions between 2."1.33[Glutaric aciduria type 1 with normal evolution: follow-up of one case until adult age]. ( Garcia-Segura, JM; Merinero, B; Pascual-Castroviejo, I; Pascual-Pascual, SI; Ugarte, M; Velazquez, R; Viaño, J, 2005)
"Convulsions were prevented by intrastriatal preinjection of muscimol."1.30Pharmacological evidence for GABAergic and glutamatergic involvement in the convulsant and behavioral effects of glutaric acid. ( Begnini, J; de Bastiani, J; de Mello, CF; Fialho, DB; Jurach, A; Lima, TT; Ribeiro, MC; Wajner, M, 1998)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's5 (55.56)29.6817
2010's2 (22.22)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Brüning, CA2
Rosa, SG2
Quines, CB2
Magni, DV4
Nonemacher, NT1
Bortolatto, CF1
Nogueira, CW2
Souza, MA1
Oliveira, AP1
Furian, AF3
Oliveira, MS3
Ferreira, J2
Santos, AR1
Mello, CF3
Royes, LF3
Fighera, MR4
Gai, BM1
Yamaguchi, S1
Pascual-Castroviejo, I1
Pascual-Pascual, SI1
Merinero, B1
Ugarte, M1
Garcia-Segura, JM1
Viaño, J1
Velazquez, R1
Fiorenza, NG2
Frussa-Filho, R1
Petry, JC1
Coelho, RC1
Lima, TT1
Begnini, J1
de Bastiani, J1
Fialho, DB1
Jurach, A1
Ribeiro, MC1
Wajner, M1
de Mello, CF1
Hartley, LM1
Khwaja, OS1
Verity, CM1

Reviews

1 review available for glutaric acid and Seizures

ArticleYear
[Organic acid disorders: cerebral organic acidemia].
    Ryoikibetsu shokogun shirizu, 2002, Issue:37 Pt 6

    Topics: Brain Diseases, Metabolic; Canavan Disease; Glutarates; Glycerol; Humans; Hydroxybutyrates; Infant;

2002

Other Studies

8 other studies available for glutaric acid and Seizures

ArticleYear
The role of nitric oxide in glutaric acid-induced convulsive behavior in pup rats.
    The European journal of neuroscience, 2020, Volume: 52, Issue:7

    Topics: Animals; Arginine; Enzyme Inhibitors; Glutarates; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide;

2020
Lipopolysaccharide enhances glutaric acid-induced seizure susceptibility in rat pups: behavioral and electroencephalographic approach.
    Epilepsy research, 2011, Volume: 93, Issue:2-3

    Topics: Animals; Animals, Newborn; Antibodies; Behavior, Animal; Body Temperature; Brain Chemistry; Dose-Res

2011
m-Trifluoromethyl diphenyl diselenide attenuates glutaric acid-induced seizures and oxidative stress in rat pups: involvement of the γ-aminobutyric acidergic system.
    Journal of neuroscience research, 2012, Volume: 90, Issue:9

    Topics: Amino Acid Metabolism, Inborn Errors; Animals; Anticonvulsants; Brain Diseases, Metabolic; Disease M

2012
[Glutaric aciduria type 1 with normal evolution: follow-up of one case until adult age].
    Neurologia (Barcelona, Spain), 2005, Volume: 20, Issue:4

    Topics: Basal Ganglia; Brain; Brain Chemistry; Brain Diseases, Metabolic, Inborn; Carnitine; Cells, Cultured

2005
GM1 ganglioside prevents seizures, Na+,K+-ATPase activity inhibition and oxidative stress induced by glutaric acid and pentylenetetrazole.
    Neurobiology of disease, 2006, Volume: 22, Issue:3

    Topics: Animals; Convulsants; Dizocilpine Maleate; Electroencephalography; Excitatory Amino Acid Antagonists

2006
Creatine decreases convulsions and neurochemical alterations induced by glutaric acid in rats.
    Brain research, 2007, Dec-14, Volume: 1185

    Topics: Analysis of Variance; Animals; Anticonvulsants; Behavior, Animal; Brain Chemistry; Creatine; Disease

2007
Pharmacological evidence for GABAergic and glutamatergic involvement in the convulsant and behavioral effects of glutaric acid.
    Brain research, 1998, Aug-17, Volume: 802, Issue:1-2

    Topics: Animals; Behavior, Animal; Convulsants; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relation

1998
Glutaric aciduria type 1 and nonaccidental head injury.
    Pediatrics, 2001, Volume: 107, Issue:1

    Topics: Brain Diseases, Metabolic, Inborn; Child Abuse; Craniocerebral Trauma; Diagnosis, Differential; Drai

2001