Substance | Description | Relationhip Strength | Studies | Trials | Classes | Roles |
bw 245c | [no description available] | medium | 7 | 0 | imidazolidine-2,4-dione; monocarboxylic acid; secondary alcohol | |
bw a868c | [no description available] | medium | 2 | 0 | imidazolidine-2,4-dione | |
prostaglandin d2 | [no description available] | medium | 20 | 0 | prostaglandins D | human metabolite; mouse metabolite |
dinoprostone | [no description available] | medium | 120 | 0 | prostaglandins E | human metabolite; mouse metabolite; oxytocic |
dinoprostone | [no description available] | medium | 120 | 1 | prostaglandins E | human metabolite; mouse metabolite; oxytocic |
dinoprost | [no description available] | medium | 18 | 0 | monocarboxylic acid; prostaglandins Falpha | human metabolite; mouse metabolite |
alprostadil | [no description available] | medium | 31 | 0 | prostaglandins E | anticoagulant; human metabolite; platelet aggregation inhibitor; vasodilator agent |
11-deoxyprostaglandin e1 | [no description available] | medium | 2 | 0 | prostanoid | |
16,16-dimethylprostaglandin e2 | [no description available] | medium | 2 | 0 | cyclopentanones; monocarboxylic acid; prostanoid; secondary allylic alcohol | anti-ulcer drug; gastrointestinal drug; radiation protective agent |
17-phenyltrinorprostaglandin e2 | [no description available] | medium | 3 | 0 | alicyclic ketone; beta-hydroxy ketone; hydroxy monocarboxylic acid; olefinic compound; oxo monocarboxylic acid; prostanoid; secondary alcohol | human metabolite; prostaglandin receptor agonist |
ah 13205 | [no description available] | medium | 4 | 0 | | |
cicaprost | [no description available] | medium | 4 | 0 | monoterpenoid | |
fluprostenol | [no description available] | medium | 3 | 0 | (trifluoromethyl)benzenes; hydroxy monocarboxylic acid; prostaglandins Falpha | abortifacient; antiglaucoma drug; antihypertensive agent; female contraceptive drug; prostaglandin receptor agonist |
m&b 28,767 | [no description available] | medium | 3 | 0 | | |
u-44619 | [no description available] | medium | 3 | 0 | | |
s 145 | [no description available] | medium | 1 | 0 | monoterpenoid | |
sulprostone | [no description available] | medium | 16 | 0 | prostanoid | |
ono 1301 | [no description available] | medium | 1 | 0 | | |
sq 28053 | [no description available] | medium | 2 | 0 | | |
19-hydroxyprostaglandin e1 | [no description available] | medium | 1 | 0 | | |
vapiprost | [no description available] | medium | 5 | 0 | | |
sc-19220 | [no description available] | medium | 2 | 0 | aromatic ether | |
ah 23848 | [no description available] | medium | 21 | 0 | (4Z)-7-{5-[([1,1'-biphenyl]-4-yl)methoxy]-2-(morpholin-4-yl)-3-oxocyclopentyl}hept-4-enoic acid | |
enprostil | [no description available] | medium | 4 | 0 | | |
ono 8713 | [no description available] | medium | 1 | 0 | | |
misoprostol | [no description available] | medium | 9 | 0 | | |
cloprostenol | [no description available] | medium | 3 | 0 | prostanoid | |
latanoprost | [no description available] | medium | 1 | 0 | isopropyl ester; prostaglandins Falpha; triol | antiglaucoma drug; antihypertensive agent; EC 4.2.1.1 (carbonic anhydrase) inhibitor; prodrug |
misoprostol acid | [no description available] | medium | 1 | 0 | | |
phxa 85 | [no description available] | medium | 1 | 0 | hydroxy monocarboxylic acid; prostaglandins Falpha | antiglaucoma drug; antihypertensive agent; EC 4.2.1.1 (carbonic anhydrase) inhibitor |
epoprostenol | [no description available] | medium | 1 | 0 | prostaglandins I | mouse metabolite |
2-[[2-furanyl(oxo)methyl]amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid ethyl ester | [no description available] | medium | 1 | 0 | organosulfur heterocyclic compound | |
butaprost | [no description available] | medium | 1 | 0 | | |
tg4-155 | [no description available] | medium | 1 | 0 | | |
cp533536 | [no description available] | medium | 1 | 0 | monocarboxylic acid | |
cp 544326 | [no description available] | medium | 1 | 0 | | |
pf-04418948 | [no description available] | medium | 1 | 0 | | |
tg6-10-1 | [no description available] | medium | 1 | 0 | | |
butaprost | [no description available] | medium | 21 | 0 | | |
alpha-aminopyridine | [no description available] | medium | 1 | 0 | | |
ribociclib | [no description available] | medium | 1 | 0 | | |
bay 11-7082 | [no description available] | medium | 1 | 0 | nitrile; sulfone | apoptosis inducer; EC 2.7.11.10 (IkappaB kinase) inhibitor; EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor; non-steroidal anti-inflammatory drug; platelet aggregation inhibitor |
celecoxib | [no description available] | medium | 5 | 0 | organofluorine compound; pyrazoles; sulfonamide; toluenes | cyclooxygenase 2 inhibitor; geroprotector; non-narcotic analgesic; non-steroidal anti-inflammatory drug |
interleukin-8 | [no description available] | medium | 4 | 0 | | |
pyrrolidonecarboxylic acid | [no description available] | medium | 1 | 0 | 5-oxoproline; L-proline derivative; non-proteinogenic L-alpha-amino acid | algal metabolite |
gamma-aminobutyric acid | [no description available] | medium | 2 | 0 | amino acid zwitterion; gamma-amino acid; monocarboxylic acid | human metabolite; neurotransmitter; Saccharomyces cerevisiae metabolite; signalling molecule |
nickel sulfate | [no description available] | medium | 1 | 0 | metal sulfate | allergen |
nickel | [no description available] | medium | 1 | 0 | metal allergen; nickel group element atom | epitope; micronutrient |
pd 98059 | [no description available] | medium | 1 | 0 | aromatic amine; monomethoxyflavone | EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; geroprotector |
semaxinib | [no description available] | medium | 1 | 0 | olefinic compound; oxindoles; pyrroles | angiogenesis modulating agent; antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; vascular endothelial growth factor receptor antagonist |
pyrroles | [no description available] | medium | 4 | 0 | pyrrole; secondary amine | |
l-161982 | [no description available] | medium | 6 | 0 | biphenyls | |
n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide | [no description available] | medium | 11 | 0 | aromatic ether; C-nitro compound; sulfonamide | antineoplastic agent; cyclooxygenase 2 inhibitor |
thiophenes | [no description available] | medium | 8 | 0 | mancude organic heteromonocyclic parent; monocyclic heteroarene; thiophenes; volatile organic compound | non-polar solvent |
triazoles | [no description available] | medium | 6 | 0 | 1,2,3-triazole | |
palmitic acid | [no description available] | medium | 1 | 0 | long-chain fatty acid; straight-chain saturated fatty acid | algal metabolite; Daphnia magna metabolite; EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor; plant metabolite |
ng-nitroarginine methyl ester | [no description available] | medium | 5 | 0 | alpha-amino acid ester; L-arginine derivative; methyl ester; N-nitro compound | EC 1.14.13.39 (nitric oxide synthase) inhibitor |
nimesulide | [no description available] | medium | 1 | 0 | aromatic ether; C-nitro compound; sulfonamide | cyclooxygenase 2 inhibitor; non-steroidal anti-inflammatory drug |
glyceryl 2-arachidonate | [no description available] | medium | 1 | 0 | 2-acylglycerol 20:4; endocannabinoid | human metabolite |
muscarine | [no description available] | medium | 1 | 0 | monosaccharide | |
capsaicin | [no description available] | medium | 2 | 0 | capsaicinoid | non-narcotic analgesic; TRPV1 agonist; voltage-gated sodium channel blocker |
dup 697 | [no description available] | medium | 2 | 0 | thiophenes | |
capsazepine | [no description available] | medium | 2 | 0 | benzazepine; catechols; monochlorobenzenes; thioureas | capsaicin receptor antagonist |
1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole | [no description available] | medium | 1 | 0 | benzoic acid; imidazolines; organic radical | apoptosis inhibitor; radical scavenger |
arachidonic acid | [no description available] | medium | 3 | 0 | icosa-5,8,11,14-tetraenoic acid; long-chain fatty acid; omega-6 fatty acid | Daphnia galeata metabolite; EC 3.1.1.1 (carboxylesterase) inhibitor; human metabolite; mouse metabolite |
quinazolines | [no description available] | medium | 1 | 0 | azaarene; mancude organic heterobicyclic parent; ortho-fused heteroarene; quinazolines | |
saracatinib | [no description available] | medium | 1 | 0 | aromatic ether; benzodioxoles; diether; N-methylpiperazine; organochlorine compound; oxanes; quinazolines; secondary amino compound | anticoronaviral agent; antineoplastic agent; apoptosis inducer; autophagy inducer; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; radiosensitizing agent |
cay 10580 | [no description available] | medium | 1 | 0 | hydroxy monocarboxylic acid; pyrrolidin-2-ones; secondary alcohol | prostaglandin receptor agonist |
ondansetron | [no description available] | medium | 1 | 0 | carbazoles | |
kt 5720 | [no description available] | medium | 3 | 0 | carboxylic ester; gamma-lactam; hemiaminal; indolocarbazole; organic heterooctacyclic compound; semisynthetic derivative; tertiary alcohol | EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor |
hydrazine | [no description available] | medium | 12 | 1 | azane; hydrazines | EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor |
sc 51089 | [no description available] | medium | 4 | 1 | | |
thromboplastin | [no description available] | medium | 1 | 1 | | |
fluorouracil | [no description available] | medium | 1 | 0 | nucleobase analogue; organofluorine compound | antimetabolite; antineoplastic agent; environmental contaminant; immunosuppressive agent; radiosensitizing agent; xenobiotic |
indomethacin | [no description available] | medium | 18 | 0 | aromatic ether; indole-3-acetic acids; monochlorobenzenes; N-acylindole | analgesic; drug metabolite; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; environmental contaminant; gout suppressant; non-steroidal anti-inflammatory drug; xenobiotic metabolite; xenobiotic |
oxytocin | [no description available] | medium | 1 | 0 | heterodetic cyclic peptide; peptide hormone | oxytocic; vasodilator agent |
taprostene | [no description available] | medium | 1 | 0 | benzoic acids | |
leukotriene b4 | [no description available] | medium | 2 | 0 | dihydroxy monocarboxylic acid; hydroxy polyunsaturated fatty acid; leukotriene; long-chain fatty acid | human metabolite; mouse metabolite; plant metabolite; vasoconstrictor agent |
l 663536 | [no description available] | medium | 1 | 0 | aryl sulfide; indoles; monocarboxylic acid; monochlorobenzenes | antineoplastic agent; EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor; leukotriene antagonist |
mifepristone | [no description available] | medium | 1 | 0 | 3-oxo-Delta(4) steroid; acetylenic compound; tertiary amino compound | abortifacient; contraceptive drug; hormone antagonist; synthetic oral contraceptive |
mk-0524 | [no description available] | medium | 1 | 0 | indolyl carboxylic acid | |
ethacrynic acid | [no description available] | medium | 1 | 0 | aromatic ether; aromatic ketone; dichlorobenzene; monocarboxylic acid | EC 2.5.1.18 (glutathione transferase) inhibitor; ion transport inhibitor; loop diuretic |
15-deoxyprostaglandin j2 | [no description available] | medium | 1 | 0 | | |
acetylcysteine | [no description available] | medium | 1 | 0 | acetylcysteine; L-cysteine derivative; N-acetyl-L-amino acid | antidote to paracetamol poisoning; antiinfective agent; antioxidant; antiviral drug; ferroptosis inhibitor; geroprotector; human metabolite; mucolytic; radical scavenger; vulnerary |
colforsin | [no description available] | medium | 5 | 0 | acetate ester; cyclic ketone; labdane diterpenoid; organic heterotricyclic compound; tertiary alpha-hydroxy ketone; triol | adenylate cyclase agonist; anti-HIV agent; antihypertensive agent; plant metabolite; platelet aggregation inhibitor; protein kinase A agonist |
ethylmaleimide | [no description available] | medium | 1 | 0 | maleimides | anticoronaviral agent; EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor; EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor; EC 2.7.1.1 (hexokinase) inhibitor |
hydantoins | [no description available] | medium | 7 | 0 | imidazolidine-2,4-dione | |
milrinone | [no description available] | medium | 1 | 0 | bipyridines; nitrile; pyridone | cardiotonic drug; EC 3.1.4.17 (3',5'-cyclic-nucleotide phosphodiesterase) inhibitor; platelet aggregation inhibitor; vasodilator agent |
isoproterenol | [no description available] | medium | 4 | 0 | catechols; secondary alcohol; secondary amino compound | beta-adrenergic agonist; bronchodilator agent; cardiotonic drug; sympathomimetic agent |
sq 29548 | [no description available] | medium | 9 | 0 | | |
1-ethyl-2-benzimidazolinone | [no description available] | medium | 1 | 0 | imidazoles | |
7-nitroindazole | [no description available] | medium | 2 | 0 | | |
methionine | [no description available] | medium | 1 | 0 | aspartate family amino acid; L-alpha-amino acid; methionine zwitterion; methionine; proteinogenic amino acid | antidote to paracetamol poisoning; human metabolite; micronutrient; mouse metabolite; nutraceutical |
bradykinin | [no description available] | medium | 5 | 0 | oligopeptide | human blood serum metabolite; vasodilator agent |
cardiovascular agents | [no description available] | medium | 1 | 0 | | |
indazoles | [no description available] | medium | 2 | 0 | indazole | |
ketamine | [no description available] | medium | 1 | 0 | cyclohexanones; monochlorobenzenes; secondary amino compound | analgesic; environmental contaminant; intravenous anaesthetic; neurotoxin; NMDA receptor antagonist; xenobiotic |
angiotensin ii | [no description available] | medium | 1 | 0 | amino acid zwitterion; angiotensin II | human metabolite |
glycine | [no description available] | medium | 1 | 0 | alpha-amino acid; amino acid zwitterion; proteinogenic amino acid; serine family amino acid | EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor; fundamental metabolite; hepatoprotective agent; micronutrient; neurotransmitter; NMDA receptor agonist; nutraceutical |
flurbiprofen | [no description available] | medium | 2 | 0 | fluorobiphenyl; monocarboxylic acid | antipyretic; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug |
glutamine | [no description available] | medium | 1 | 0 | amino acid zwitterion; glutamine family amino acid; glutamine; L-alpha-amino acid; polar amino acid zwitterion; proteinogenic amino acid | EC 1.14.13.39 (nitric oxide synthase) inhibitor; Escherichia coli metabolite; human metabolite; metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite |
glutamic acid | [no description available] | medium | 3 | 0 | glutamic acid; glutamine family amino acid; L-alpha-amino acid; proteinogenic amino acid | Escherichia coli metabolite; ferroptosis inducer; micronutrient; mouse metabolite; neurotransmitter; nutraceutical |
8-isoprostaglandin e2 | [no description available] | medium | 2 | 0 | cyclic ketone; diol; prostanoid; secondary alcohol | bronchoconstrictor agent; human metabolite; rat metabolite; vasoconstrictor agent |
furegrelate | [no description available] | medium | 1 | 0 | benzofurans | |
benzofurans | [no description available] | medium | 2 | 0 | | |
dibenz(b,f)(1,4)oxazepine-10(11h)-carboxylic acid, 8-chloro-, 2-acetylhydrazide | [no description available] | medium | 14 | 0 | | |
al 8810 | [no description available] | medium | 2 | 0 | long-chain fatty acid | |
atrial natriuretic factor | [no description available] | medium | 1 | 0 | polypeptide | |
naproxen | [no description available] | medium | 3 | 0 | methoxynaphthalene; monocarboxylic acid | antipyretic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; drug allergen; environmental contaminant; gout suppressant; non-narcotic analgesic; non-steroidal anti-inflammatory drug; xenobiotic |
2-methyl-5-ht | [no description available] | medium | 1 | 0 | tryptamines | serotonergic agonist |
dimethyl sulfoxide | [no description available] | medium | 3 | 0 | sulfoxide; volatile organic compound | alkylating agent; antidote; Escherichia coli metabolite; geroprotector; MRI contrast agent; non-narcotic analgesic; polar aprotic solvent; radical scavenger |
cyclopentane | [no description available] | medium | 1 | 0 | cycloalkane; cyclopentanes; volatile organic compound | non-polar solvent |
ro3244794 | [no description available] | medium | 1 | 0 | | |
wortmannin | [no description available] | medium | 1 | 0 | acetate ester; cyclic ketone; delta-lactone; organic heteropentacyclic compound | anticoronaviral agent; antineoplastic agent; autophagy inhibitor; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; geroprotector; Penicillium metabolite; radiosensitizing agent |
cycloheximide | [no description available] | medium | 1 | 0 | antibiotic fungicide; cyclic ketone; dicarboximide; piperidine antibiotic; piperidones; secondary alcohol | anticoronaviral agent; bacterial metabolite; ferroptosis inhibitor; neuroprotective agent; protein synthesis inhibitor |
h 89 | [no description available] | medium | 7 | 0 | N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide | |
adenine | [no description available] | medium | 1 | 0 | 6-aminopurines; purine nucleobase | Daphnia magna metabolite; Escherichia coli metabolite; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite |
9-(tetrahydro-2-furyl)-adenine | [no description available] | medium | 1 | 0 | | |
tetradecanoylphorbol acetate | [no description available] | medium | 1 | 0 | acetate ester; diester; phorbol ester; tertiary alpha-hydroxy ketone; tetradecanoate ester | antineoplastic agent; apoptosis inducer; carcinogenic agent; mitogen; plant metabolite; protein kinase C agonist; reactive oxygen species generator |
ono ae 248 | [no description available] | medium | 1 | 0 | | |
ono-ae1-329 | [no description available] | medium | 1 | 0 | | |
ono-di-004 | [no description available] | medium | 1 | 0 | | |
tetrodotoxin | [no description available] | medium | 5 | 0 | azatetracycloalkane; oxatetracycloalkane; quinazoline alkaloid | animal metabolite; bacterial metabolite; marine metabolite; neurotoxin; voltage-gated sodium channel blocker |
cuprizone | [no description available] | medium | 1 | 0 | organonitrogen compound; organooxygen compound | |
fluorescein-5-isothiocyanate | [no description available] | medium | 1 | 0 | fluorescein isothiocyanate | |
15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid | [no description available] | medium | 16 | 0 | | |
ici 192605 | [no description available] | medium | 3 | 0 | | |
thromboxanes | [no description available] | medium | 4 | 0 | | |
carbachol | [no description available] | medium | 2 | 0 | ammonium salt; carbamate ester | cardiotonic drug; miotic; muscarinic agonist; nicotinic acetylcholine receptor agonist; non-narcotic analgesic |
piperidines | [no description available] | medium | 1 | 0 | | |
l 733060 | [no description available] | medium | 1 | 0 | piperidines | |
substance p | [no description available] | medium | 1 | 0 | peptide | neurokinin-1 receptor agonist; neurotransmitter; vasodilator agent |
vitamin k 3 | [no description available] | medium | 1 | 0 | 1,4-naphthoquinones; vitamin K | angiogenesis inhibitor; antineoplastic agent; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; human urinary metabolite; nutraceutical |
alpha-linolenic acid | [no description available] | medium | 1 | 0 | linolenic acid; omega-3 fatty acid | micronutrient; mouse metabolite; nutraceutical |
lipoxin a4 | [no description available] | medium | 1 | 0 | hydroxy polyunsaturated fatty acid; lipoxin; long-chain fatty acid | human metabolite; metabolite |
resolvin d2 | [no description available] | medium | 1 | 0 | hydroxy polyunsaturated fatty acid; resolvin; secondary allylic alcohol; triol | anti-inflammatory agent; anti-obesity agent; estrogen receptor agonist; human xenobiotic metabolite; rat metabolite |
resolvin d1 | [no description available] | medium | 1 | 0 | hydroxy polyunsaturated fatty acid; resolvin; triol | anti-inflammatory agent |
thromboxane a2 | [no description available] | medium | 8 | 0 | epoxy monocarboxylic acid; thromboxanes A | mouse metabolite |
ro 31-8220 | [no description available] | medium | 1 | 0 | imidothiocarbamic ester; indoles; maleimides | EC 2.7.11.13 (protein kinase C) inhibitor |
cyclic gmp | [no description available] | medium | 1 | 0 | 3',5'-cyclic purine nucleotide; guanyl ribonucleotide | Escherichia coli metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite |
u 73122 | [no description available] | medium | 2 | 0 | aromatic ether; aza-steroid; maleimides | EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor |
ucn 1028 c | [no description available] | medium | 1 | 0 | | |
xanthenes | [no description available] | medium | 60 | 0 | xanthene | |
u 73343 | [no description available] | medium | 1 | 0 | | |
prostaglandin a2 | [no description available] | medium | 1 | 0 | prostaglandins A | human metabolite |
yohimbine | [no description available] | medium | 3 | 0 | methyl 17-hydroxy-20xi-yohimban-16-carboxylate | alpha-adrenergic antagonist; dopamine receptor D2 antagonist; serotonergic antagonist |
leukotriene d4 | [no description available] | medium | 3 | 0 | dipeptide; leukotriene; organic sulfide | bronchoconstrictor agent; human metabolite; mouse metabolite |
iloprost | [no description available] | medium | 7 | 0 | carbobicyclic compound; monocarboxylic acid; secondary alcohol | platelet aggregation inhibitor; vasodilator agent |
1-amino-1,3-dicarboxycyclopentane | [no description available] | medium | 1 | 0 | | |
2-amino-5-phosphonovalerate | [no description available] | medium | 1 | 0 | non-proteinogenic alpha-amino acid | NMDA receptor antagonist |
cycloleucine | [no description available] | medium | 1 | 0 | non-proteinogenic alpha-amino acid | EC 2.5.1.6 (methionine adenosyltransferase) inhibitor |
quisqualic acid | [no description available] | medium | 1 | 0 | non-proteinogenic alpha-amino acid | |
valine | [no description available] | medium | 1 | 0 | L-alpha-amino acid zwitterion; L-alpha-amino acid; proteinogenic amino acid; pyruvate family amino acid; valine | algal metabolite; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite |
8-bromo cyclic adenosine monophosphate | [no description available] | medium | 2 | 0 | 3',5'-cyclic purine nucleotide; adenyl ribonucleotide; organobromine compound | antidepressant; protein kinase agonist |
nitroarginine | [no description available] | medium | 1 | 0 | guanidines; L-arginine derivative; N-nitro compound; non-proteinogenic L-alpha-amino acid | |
6-ketoprostaglandin f1 alpha | [no description available] | medium | 1 | 0 | prostaglandins Falpha | human metabolite; mouse metabolite |
diclofenac | [no description available] | medium | 1 | 0 | amino acid; aromatic amine; dichlorobenzene; monocarboxylic acid; secondary amino compound | antipyretic; drug allergen; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; environmental contaminant; non-narcotic analgesic; non-steroidal anti-inflammatory drug; xenobiotic |
aspirin | [no description available] | medium | 1 | 0 | benzoic acids; phenyl acetates; salicylates | anticoagulant; antipyretic; cyclooxygenase 1 inhibitor; cyclooxygenase 2 inhibitor; drug allergen; EC 1.1.1.188 (prostaglandin-F synthase) inhibitor; geroprotector; non-narcotic analgesic; non-steroidal anti-inflammatory drug; plant activator; platelet aggregation inhibitor; prostaglandin antagonist; teratogenic agent |
loxoprofen | [no description available] | medium | 1 | 0 | cyclopentanones; monocarboxylic acid | antipyretic; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; non-narcotic analgesic; non-steroidal anti-inflammatory drug; prodrug |
calpain | [no description available] | medium | 1 | 0 | | |
framycetin | [no description available] | medium | 1 | 0 | aminoglycoside | allergen; antibacterial drug; Escherichia coli metabolite |
pimagedine | [no description available] | medium | 1 | 0 | guanidines; one-carbon compound | EC 1.14.13.39 (nitric oxide synthase) inhibitor; EC 1.4.3.4 (monoamine oxidase) inhibitor |
nifedipine | [no description available] | medium | 2 | 0 | C-nitro compound; dihydropyridine; methyl ester | calcium channel blocker; human metabolite; tocolytic agent; vasodilator agent |
adenosine-3',5'-cyclic phosphorothioate | [no description available] | medium | 1 | 0 | nucleoside 3',5'-cyclic phosphorothioate | |
phenyl acetate | [no description available] | medium | 1 | 0 | benzenes; phenyl acetates | |
formaldehyde | [no description available] | medium | 1 | 0 | aldehyde; one-carbon compound | allergen; carcinogenic agent; disinfectant; EC 3.5.1.4 (amidase) inhibitor; environmental contaminant; Escherichia coli metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite |
l-826266 | [no description available] | medium | 1 | 0 | | |
1-palmitoyl-2-(5-oxovaleroyl)-sn-glycero-3-phosphorylcholine | [no description available] | medium | 1 | 0 | 1,2-diacyl-sn-glycero-3-phosphocholine; aldehyde | apoptosis inducer |
phosphatidylcholines | [no description available] | medium | 1 | 0 | 1,2-diacyl-sn-glycero-3-phosphocholine | |
icatibant | [no description available] | medium | 1 | 0 | | |
n-(3-(aminomethyl)benzyl)acetamidine | [no description available] | medium | 1 | 0 | aralkylamine; carboxamidine; primary amino compound | angiogenesis inhibitor; EC 1.14.13.39 (nitric oxide synthase) inhibitor; geroprotector |
iberiotoxin | [no description available] | medium | 1 | 0 | | |
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1h-imidazole | [no description available] | medium | 1 | 0 | ether; imidazoles; monomethoxybenzene | TRP channel blocker |
2-aminoethoxydiphenyl borate | [no description available] | medium | 1 | 0 | organoboron compound; primary amino compound | calcium channel blocker; IP3 receptor antagonist; potassium channel opener |
charybdotoxin | [no description available] | medium | 2 | 0 | | |
cortisone | [no description available] | medium | 1 | 0 | 11-oxo steroid; 17alpha-hydroxy steroid; 20-oxo steroid; 21-hydroxy steroid; 3-oxo-Delta(4) steroid; C21-steroid; glucocorticoid; primary alpha-hydroxy ketone; tertiary alpha-hydroxy ketone | human metabolite; mouse metabolite |
potassium chloride | [no description available] | medium | 1 | 0 | inorganic chloride; inorganic potassium salt; potassium salt | fertilizer |
phenylephrine | [no description available] | medium | 1 | 0 | phenols; phenylethanolamines; secondary amino compound | alpha-adrenergic agonist; cardiotonic drug; mydriatic agent; nasal decongestant; protective agent; sympathomimetic agent; vasoconstrictor agent |
ramatroban | [no description available] | medium | 3 | 0 | organic molecular entity | |
terutroban | [no description available] | medium | 1 | 0 | | |
inositol 1,4,5-trisphosphate | [no description available] | medium | 2 | 0 | myo-inositol trisphosphate | mouse metabolite |
l 670596 | [no description available] | medium | 1 | 0 | carbazoles | |
gr 63799x | [no description available] | medium | 2 | 0 | | |
apomorphine | [no description available] | medium | 1 | 0 | aporphine alkaloid | alpha-adrenergic drug; antidyskinesia agent; antiparkinson drug; dopamine agonist; emetic; serotonergic drug |
melatonin | [no description available] | medium | 1 | 0 | acetamides; tryptamines | anticonvulsant; central nervous system depressant; geroprotector; hormone; human metabolite; immunological adjuvant; mouse metabolite; radical scavenger |
m&b 28,767 | [no description available] | medium | 2 | 0 | | |
glucose, (beta-d)-isomer | [no description available] | medium | 1 | 0 | D-glucopyranose | epitope; mouse metabolite |
n-formylmethionine leucyl-phenylalanine | [no description available] | medium | 1 | 0 | tripeptide | |
1-hexadecyl-2-acetyl-glycero-3-phosphocholine | [no description available] | medium | 3 | 0 | 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine | antihypertensive agent; beta-adrenergic antagonist; bronchoconstrictor agent; hematologic agent; vasodilator agent |
8-epi-prostaglandin f2alpha | [no description available] | medium | 2 | 0 | F2-isoprostane | biomarker; bronchoconstrictor agent; vasoconstrictor agent |
prostaglandin e3 | [no description available] | medium | 1 | 0 | prostaglandins E | human metabolite |
erythrosine | [no description available] | medium | 1 | 0 | | |
oxotremorine | [no description available] | medium | 1 | 0 | N-alkylpyrrolidine | |
scopolamine hydrobromide | [no description available] | medium | 1 | 0 | | |
alpha-methylhistamine | [no description available] | medium | 1 | 0 | aralkylamino compound; imidazoles | animal metabolite; H3-receptor agonist |
pentylenetetrazole | [no description available] | medium | 1 | 0 | organic heterobicyclic compound; organonitrogen heterocyclic compound | |
sodium selenite | [no description available] | medium | 1 | 0 | inorganic sodium salt; selenite salt | nutraceutical |
histamine | [no description available] | medium | 1 | 0 | aralkylamino compound; imidazoles | human metabolite; mouse metabolite; neurotransmitter |
cv 3988 | [no description available] | medium | 1 | 0 | | |
pf 5901 | [no description available] | medium | 1 | 0 | quinolines | |
adenosine monophosphate | [no description available] | medium | 1 | 0 | adenosine 5'-phosphate; purine ribonucleoside 5'-monophosphate | adenosine A1 receptor agonist; cofactor; EC 3.1.3.1 (alkaline phosphatase) inhibitor; EC 3.1.3.11 (fructose-bisphosphatase) inhibitor; fundamental metabolite; micronutrient; nutraceutical |
arachidonyltrifluoromethane | [no description available] | medium | 1 | 0 | fatty acid derivative; ketone; olefinic compound; organofluorine compound | EC 3.1.1.4 (phospholipase A2) inhibitor |
beta-alanine | [no description available] | medium | 1 | 0 | amino acid zwitterion; beta-amino acid | agonist; fundamental metabolite; human metabolite; inhibitor; neurotransmitter |
l 745337 | [no description available] | medium | 1 | 0 | | |
2,2-dimethyl-beta-alanine | [no description available] | medium | 1 | 0 | | |
aa 861 | [no description available] | medium | 1 | 0 | 1,4-benzoquinones; acetylenic compound; primary alcohol | EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor; ferroptosis inhibitor |
thromboxane b2 | [no description available] | medium | 1 | 0 | thromboxanes B | human metabolite; mouse metabolite |
baicalein | [no description available] | medium | 1 | 0 | trihydroxyflavone | angiogenesis inhibitor; anti-inflammatory agent; antibacterial agent; anticoronaviral agent; antifungal agent; antineoplastic agent; antioxidant; apoptosis inducer; EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; EC 3.4.21.26 (prolyl oligopeptidase) inhibitor; EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor; EC 4.1.1.17 (ornithine decarboxylase) inhibitor; ferroptosis inhibitor; geroprotector; hormone antagonist; plant metabolite; prostaglandin antagonist; radical scavenger |
bisindolylmaleimide i | [no description available] | medium | 1 | 0 | | |
16,16-dimethylprostaglandin f2alpha | [no description available] | medium | 1 | 0 | | |
lutein | [no description available] | medium | 1 | 0 | carotenol | food colouring; plant metabolite |
bumetanide | [no description available] | medium | 1 | 0 | amino acid; benzoic acids; sulfonamide | diuretic; EC 3.6.3.49 (channel-conductance-controlling ATPase) inhibitor |
chlorine | [no description available] | medium | 3 | 0 | halide anion; monoatomic chlorine | cofactor; Escherichia coli metabolite; human metabolite |
rioprostil | [no description available] | medium | 1 | 0 | aliphatic alcohol | |
16,16-dimethylprostaglandin e | [no description available] | medium | 1 | 0 | prostanoid | |
carboprostacyclin | [no description available] | medium | 1 | 0 | prostanoid | |
morphine | [no description available] | medium | 1 | 0 | morphinane alkaloid; organic heteropentacyclic compound; tertiary amino compound | anaesthetic; drug allergen; environmental contaminant; geroprotector; mu-opioid receptor agonist; opioid analgesic; plant metabolite; vasodilator agent; xenobiotic |
quinacrine | [no description available] | medium | 1 | 0 | acridines; aromatic ether; organochlorine compound; tertiary amino compound | antimalarial; EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor |
calcimycin | [no description available] | medium | 1 | 0 | benzoxazole | |
1-methyl-3-isobutylxanthine | [no description available] | medium | 2 | 0 | 3-isobutyl-1-methylxanthine | |
8-((4-chlorophenyl)thio)cyclic-3',5'-amp | [no description available] | medium | 1 | 0 | 3',5'-cyclic purine nucleotide; adenyl ribonucleotide; aryl sulfide; organochlorine compound | protein kinase agonist |
cytarabine | [no description available] | medium | 1 | 0 | beta-D-arabinoside; monosaccharide derivative; pyrimidine nucleoside | antimetabolite; antineoplastic agent; antiviral agent; immunosuppressive agent |
zk 110841 | [no description available] | medium | 1 | 0 | | |
adenosine-5'-(n-ethylcarboxamide) | [no description available] | medium | 1 | 0 | adenosines; monocarboxylic acid amide | adenosine A1 receptor agonist; adenosine A2A receptor agonist; antineoplastic agent; EC 3.1.4.* (phosphoric diester hydrolase) inhibitor; vasodilator agent |
adenosine diphosphate | [no description available] | medium | 1 | 0 | adenosine 5'-phosphate; purine ribonucleoside 5'-diphosphate | fundamental metabolite; human metabolite |
adenosine | [no description available] | medium | 1 | 0 | adenosines; purines D-ribonucleoside | analgesic; anti-arrhythmia drug; fundamental metabolite; human metabolite; vasodilator agent |
ay 23626 | [no description available] | medium | 1 | 0 | | |
xanthone | [no description available] | low | 0 | 0 | xanthones | insecticide |
2-Methoxyxanthone | [no description available] | low | 0 | 0 | xanthones | |
vadimezan | [no description available] | low | 0 | 0 | monocarboxylic acid; xanthones | antineoplastic agent |
psorospermin | [no description available] | low | 0 | 0 | epoxide; organic heterotetracyclic compound; xanthones | antineoplastic agent; plant metabolite |
8-deoxygartanin | [no description available] | low | 0 | 0 | xanthones | |
bellidifolin | [no description available] | low | 0 | 0 | polyphenol; xanthones | EC 3.1.1.7 (acetylcholinesterase) inhibitor; hypoglycemic agent; metabolite |
demethylbellidifolin | [no description available] | low | 0 | 0 | tetrol; xanthones | antioxidant; EC 3.1.1.7 (acetylcholinesterase) inhibitor; metabolite; mutagen; radical scavenger |
euxanthone | [no description available] | low | 0 | 0 | phenols; xanthones | metabolite; plant metabolite |
gartanin | [no description available] | low | 0 | 0 | polyphenol; xanthones | antineoplastic agent; plant metabolite |
gentiacaulein | [no description available] | low | 0 | 0 | aromatic ether; polyphenol; xanthones | plant metabolite |
gentisein | [no description available] | low | 0 | 0 | polyphenol; xanthones | plant metabolite |
gentisin | [no description available] | low | 0 | 0 | aromatic ether; polyphenol; xanthones | plant metabolite |
isogentisin | [no description available] | low | 0 | 0 | aromatic ether; polyphenol; xanthones | EC 1.4.3.4 (monoamine oxidase) inhibitor; plant metabolite |
mangiferin | [no description available] | low | 0 | 0 | C-glycosyl compound; xanthones | anti-inflammatory agent; antioxidant; hypoglycemic agent; plant metabolite |
mangostin | [no description available] | low | 0 | 0 | aromatic ether; phenols; xanthones | antimicrobial agent; antineoplastic agent; antioxidant; plant metabolite |
1,8-dihydroxy-3,7-dimethoxyxanthone | [no description available] | low | 0 | 0 | aromatic ether; polyphenol; xanthones | plant metabolite |
norathyriol | [no description available] | low | 0 | 0 | polyphenol; xanthones | antineoplastic agent; EC 2.7.11.13 (protein kinase C) inhibitor; plant metabolite |
norlichexanthone | [no description available] | low | 0 | 0 | polyphenol; xanthones | antimalarial; fungal metabolite |
norswertianolin | [no description available] | low | 0 | 0 | beta-D-glucoside; xanthones | EC 3.1.1.7 (acetylcholinesterase) inhibitor; metabolite |
swerchirin | [no description available] | low | 0 | 0 | aromatic ether; phenols; xanthones | hypoglycemic agent; metabolite |
1,2,8-trihydroxy-6-methoxyxanthone | [no description available] | low | 0 | 0 | aromatic ether; polyphenol; xanthones | antioxidant; plant metabolite |
isomangiferin | [no description available] | low | 0 | 0 | C-glycosyl compound; polyphenol; xanthones | anti-HSV-1 agent; plant metabolite |
macluraxanthone b | [no description available] | low | 0 | 0 | phenols; xanthones | anti-HIV agent; antineoplastic agent; metabolite |
lichexanthone | [no description available] | low | 0 | 0 | aromatic ether; phenols; xanthones | plant metabolite |
decussatin | [no description available] | low | 0 | 0 | aromatic ether; phenols; xanthones | plant metabolite |
gamma-mangostin | [no description available] | low | 0 | 0 | phenols; xanthones | antineoplastic agent; plant metabolite; protein kinase inhibitor |
1,7-dihydroxy-4-methoxyxanthone | [no description available] | low | 0 | 0 | aromatic ether; phenols; xanthones | metabolite; plant metabolite |
beta-Mangostin | [no description available] | low | 0 | 0 | xanthones | |
9-Hydroxycalabaxanthone | [no description available] | low | 0 | 0 | xanthones | |
nidulalin a | [no description available] | low | 0 | 0 | methyl ester; phenols; xanthones | antimicrobial agent; antineoplastic agent; Penicillium metabolite |
rubraxanthone | [no description available] | low | 0 | 0 | aromatic ether; polyphenol; xanthones | antibacterial agent; antineoplastic agent; metabolite |
garcinone e | [no description available] | low | 0 | 0 | xanthones | |
2,3,6,8-tetrahydroxy-1-(3-methylbut-2-enyl)-5-(2-methylbut-3-en-2-yl)-9h-xanthen-9-one | [no description available] | low | 0 | 0 | polyphenol; xanthones | anti-inflammatory agent; antineoplastic agent; EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor; metabolite |
3-isomangostin | [no description available] | low | 0 | 0 | xanthones | |
2-[3-(4-morpholinyl)propylamino]-9-xanthenone | [no description available] | low | 0 | 0 | xanthones | |
garcinone c | [no description available] | low | 0 | 0 | xanthones | |