spermine has been researched along with Seizures in 14 studies
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The anticonvulsant effect of 1-naphthylacetyl spermine (1-NA-Spm), an analogue of Joro spider toxin, against amygdaloid kindled seizures was studied in rats." | 7.69 | Potent and long-lasting anticonvulsant effects of 1-naphthylacetyl spermine, an analogue of Joro spider toxin, against amygdaloid kindled seizures in rats. ( Ishida, N; Kanai, H; Kato, N; Takazawa, A; Yamauchi, T; Yamazaki, O, 1996) |
| "The anticonvulsant effect of 1-naphthylacetyl spermine (1-NA-Spm), an analogue of Joro spider toxin, against amygdaloid kindled seizures was studied in rats." | 3.69 | Potent and long-lasting anticonvulsant effects of 1-naphthylacetyl spermine, an analogue of Joro spider toxin, against amygdaloid kindled seizures in rats. ( Ishida, N; Kanai, H; Kato, N; Takazawa, A; Yamauchi, T; Yamazaki, O, 1996) |
| "The early events include clonic convulsions, and the later, more general excitation, includes tremor and culminates in the development of a fatal tonic convulsion." | 1.30 | Investigation of the actions and antagonist activity of some polyamine analogues in vivo. ( Doyle, KM; Shaw, GG, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (14.29) | 18.7374 |
| 1990's | 7 (50.00) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bailey, D | 1 |
| Kirby, BP | 2 |
| Atkinson, J | 1 |
| Fixon-Owoo, S | 1 |
| Henman, MC | 1 |
| Shaw, GG | 4 |
| Doyle, KM | 3 |
| Masuko, T | 1 |
| Namiki, R | 1 |
| Nemoto, Y | 1 |
| Miyake, M | 1 |
| Kizawa, Y | 1 |
| Suzuki, T | 1 |
| Kashiwagi, K | 1 |
| Igarashi, K | 1 |
| Kusama, T | 1 |
| D'Hooge, R | 1 |
| Van de Vijver, G | 1 |
| Van Bogaert, PP | 1 |
| Marescau, B | 1 |
| Vanholder, R | 1 |
| De Deyn, PP | 1 |
| Ryder, SA | 1 |
| Seiler, N | 1 |
| Renault, J | 1 |
| Porta, R | 1 |
| Doyle, RL | 1 |
| Tatter, SB | 1 |
| Wilens, TE | 1 |
| Schatz, RA | 1 |
| Sellinger, OZ | 1 |
| Chu, PJ | 1 |
| Shirahata, A | 1 |
| Samejima, K | 1 |
| Saito, H | 1 |
| Abe, K | 1 |
| Baudry, M | 1 |
| Najm, I | 1 |
| Ishida, N | 2 |
| Kanai, H | 2 |
| Kato, N | 2 |
| Akaike, M | 1 |
| Hayashi, Y | 1 |
| Hattori, Y | 1 |
| Moriwaki, A | 1 |
| Lu, YF | 1 |
| Hori, Y | 1 |
| Takazawa, A | 1 |
| Yamazaki, O | 1 |
| Yamauchi, T | 1 |
| Lee, YK | 1 |
| Lee, SR | 1 |
| Kim, CY | 1 |
| Tsvetnenko, EZ | 1 |
| Shugaleĭ, VS | 1 |
14 other studies available for spermine and Seizures
| Article | Year |
|---|---|
Hydroxycinnamic acid amide derivatives of polyamines reverse spermine-induced CNS excitation.
Topics: Amides; Animals; Behavior, Animal; Coumaric Acids; Dose-Response Relationship, Drug; Female; Injecti | 2015 |
Neuroprotection by tosyl-polyamine derivatives through the inhibition of ionotropic glutamate receptors.
Topics: Animals; Anthraquinones; Cell Line, Tumor; Cells, Cultured; Cloning, Molecular; Dansyl Compounds; El | 2009 |
Involvement of voltage- and ligand-gated Ca2+ channels in the neuroexcitatory and synergistic effects of putative uremic neurotoxins.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Calcium Cha | 2003 |
N1-dansyl-spermine: a potent polyamine antagonist.
Topics: Animals; Central Nervous System; Dansyl Compounds; Dose-Response Relationship, Drug; Drug Interactio | 2004 |
The biosynthesis of polyamines in the brain of audiogenic seizure-susceptible and -resistant deermice.
Topics: Acoustic Stimulation; Animals; Brain; Chromatography, High Pressure Liquid; Methionine; Peromyscus; | 1981 |
N-(3-aminopropyl)-cyclohexylamine blocks facilitation by spermidine of N-methyl-DL-aspartate-induced seizure in mice in vivo.
Topics: Animals; Cyclohexylamines; Drug Interactions; Injections, Intraventricular; Male; Mice; Mice, Inbred | 1994 |
Kainate-induced seizure activity stimulates the polyamine interconversion pathway in rat brain.
Topics: Acetylation; Acetyltransferases; Animals; Biogenic Polyamines; Brain; Brain Chemistry; Kainic Acid; | 1994 |
The susceptibility of pentylenetetrazole-induced seizure in rats with hippocampal lesion induced by trimethyltin.
Topics: Administration, Oral; Animals; Dizocilpine Maleate; Hippocampus; Male; Neurons; Pentylenetetrazole; | 1993 |
Increases in brain polyamine concentrations in chemical kindling and single convulsion induced by pentylenetetrazol in rats.
Topics: Animals; Brain; Kindling, Neurologic; Male; Osmolar Concentration; Pentylenetetrazole; Putrescine; R | 1993 |
Potent and long-lasting anticonvulsant effects of 1-naphthylacetyl spermine, an analogue of Joro spider toxin, against amygdaloid kindled seizures in rats.
Topics: Amygdala; Animals; Anticoagulants; Dose-Response Relationship, Drug; Electric Stimulation; Electroen | 1996 |
Investigation of the involvement of the N-methyl-D-aspartate receptor macrocomplex in the development of spermine-induced CNS excitation in vivo.
Topics: Animals; Brain; Cerebral Ventricles; Dizocilpine Maleate; Female; Kynurenic Acid; Mice; Neuroprotect | 1996 |
Investigation of the actions and antagonist activity of some polyamine analogues in vivo.
Topics: Animals; Behavior, Animal; Biguanides; Central Nervous System; Diamines; Dose-Response Relationship, | 1998 |
Melatonin attenuates the changes in polyamine levels induced by systemic kainate administration in rat brains.
Topics: Animals; Brain; Cerebral Cortex; Chromatography, High Pressure Liquid; Hippocampus; Kainic Acid; Mal | 2000 |
[Spermine and spermidine polyamines in the brain and liver of rats under hyperoxic action].
Topics: Animals; Brain; Hyperbaric Oxygenation; Liver; Male; Oxygen; Rats; Seizures; Spermidine; Spermine; T | 1978 |