| ID Source | ID |
|---|---|
| PubMed CID | 3195 |
| CHEBI ID | 182654 |
| SCHEMBL ID | 689181 |
| MeSH ID | M0066386 |
| Synonym |
|---|
| CHEBI:182654 |
| 15-ethyl-1,11-diazapentacyclo[9.6.2.02,7.08,18.015,19]nonadeca-2,4,6,8(18)-tetraen-17-one |
| 14,15-dihydroeburnamenin-14-one |
| eburnamonine , |
| eburnamenin-14(15h)-one |
| SR-01000638676-1 |
| HMS1664F16 |
| CCG-49205 |
| FT-0635471 |
| (+)-vincamone |
| SCHEMBL689181 |
| WYJAPUKIYAZSEM-UHFFFAOYSA-N |
| 14,15-dihydroeburnamenin-14-one # |
| SR-01000638676-5 |
| SR-01000638676-4 |
| sr-01000638676 |
| AKOS025400978 |
| BRD-A60751162-001-01-4 |
| (13ar)-13a-ethyl-2,3,5,6,13,13a-hexahydro-1h-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridin-12(41h)-one |
| DTXSID10859889 |
| Class | Description |
|---|---|
| alkaloid | Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3 | High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
| AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21 | Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | 2014 | Journal of biomolecular screening, Jul, Volume: 19, Issue:6 | A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum. |
| AID1794808 | Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL). | |||
| AID1159607 | Screen for inhibitors of RMI FANCM (MM2) intereaction | 2016 | Journal of biomolecular screening, Jul, Volume: 21, Issue:6 | A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 17 (36.17) | 18.7374 |
| 1990's | 8 (17.02) | 18.2507 |
| 2000's | 5 (10.64) | 29.6817 |
| 2010's | 13 (27.66) | 24.3611 |
| 2020's | 4 (8.51) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 7 (12.50%) | 5.53% |
| Reviews | 1 (1.79%) | 6.00% |
| Case Studies | 2 (3.57%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 46 (82.14%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Article | Year |
|---|---|
| Effects of acute and chronic treatment with (-)eburnamonine on the tissue supply of oxygen. Pharmatherapeutica, Volume: 3, Issue: 2 | 1982 |
| [information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | |
| Article | Year |
|---|---|
| Experimental approach of activity and mechanism(s) of action of drugs used in cerebral metabolic insufficiency. Application to 1-eburnamonine. European neurology, Volume: 20, Issue: 3 | 1981 |
| [information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | |
| Article | Year |
|---|---|
| Protective effects of vinpocetine and structurally related drugs on the lethal consequences of hypoxia in mice. Archives internationales de pharmacodynamie et de therapie, Volume: 286, Issue: 2 | 1987 |
| Experimental clinical studies on the effect of eburnamonine in cerebrovascular disorders. Pharmacopsychiatry, Volume: 19, Issue: 5 | 1986 |
| [information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | |