A galectin-2 that is encoded in the genome of human. [PRO:DNx, UniProtKB:P05162]
Gal-2;
Beta-galactoside-binding lectin L-14-II;
HL14;
Lactose-binding lectin 2;
S-Lac lectin 2
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| methyl beta-galactoside | Homo sapiens (human) | Kd | 13,000.0000 | 3 | 3 |
| thiodigalactoside | Homo sapiens (human) | Kd | 340.0000 | 1 | 1 |
This protein enables 3 target(s):
| Target | Category | Definition |
|---|---|---|
| protein binding | molecular function | Binding to a protein. [GOC:go_curators] |
| galactoside binding | molecular function | Binding to a glycoside in which the sugar group is galactose. [GOC:jl, ISBN:0198506732] |
| carbohydrate binding | molecular function | Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. [GOC:mah] |
This protein is part of 1 target(s):
| Target | Category | Definition |
|---|---|---|
| galectin complex | cellular component | A homodimeric protein complex that is capable of binding a range of carbohydrates and is involved in anti-inflammatory and pro-apoptotic processes. [GOC:bhm, PMID:15476813, PMID:18777589, PMID:8262940] |
This protein is involved in 4 target(s):
| Target | Category | Definition |
|---|---|---|
| T cell homeostasis | biological process | The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. [GOC:mgi_curators, ISBN:0781735149] |
| positive regulation of apoptotic process | biological process | Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process. [GOC:jl, GOC:mtg_apoptosis] |
| positive regulation of inflammatory response | biological process | Any process that activates or increases the frequency, rate or extent of the inflammatory response. [GOC:ai] |
| cell-cell adhesion | biological process | The attachment of one cell to another cell via adhesion molecules. [GOC:dos] |