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enprofylline and Seizures

enprofylline has been researched along with Seizures in 4 studies

enprofylline : Xanthine bearing a propyl substituent at position 3. A bronchodilator, it is used for the symptomatic treatment of asthma and chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.

Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.

Research Excerpts

ExcerptRelevanceReference
"When isbufylline-pretreated rats were challenged with pentylenetetrazole, the EEG was characterized by a short run of wave discharges (whose duration was shorter than that of other groups)."5.28Differential effects of various xanthines on pentylenetetrazole-induced seizures in rats: an EEG and behavioural study. ( Bortot, L; Cutrufo, C; Giachetti, A; Manzini, S, 1992)
"Enprofylline, 27."5.27Effects of aminophylline and enprofylline on the protective activity of phenobarbital against amygdala-kindled seizures in rats. ( Czuczwar, SJ; Jäckel, R; Löscher, W, 1987)
"The mechanism of action of aminophylline in prolonging seizures was tested in amygdala-kindled rats."3.68Adenosine receptor antagonism accounts for the seizure-prolonging effects of aminophylline. ( Dragunow, M, 1990)
"Enprofylline is a more potent smooth muscle relaxant and antiasthmatic drug than theophylline but does not produce, e."2.37Effects of enprofylline and theophylline may show the role of adenosine. ( Andersson, KE; Kjellin, G; Persson, CG, 1986)
"When isbufylline-pretreated rats were challenged with pentylenetetrazole, the EEG was characterized by a short run of wave discharges (whose duration was shorter than that of other groups)."1.28Differential effects of various xanthines on pentylenetetrazole-induced seizures in rats: an EEG and behavioural study. ( Bortot, L; Cutrufo, C; Giachetti, A; Manzini, S, 1992)
"Enprofylline, 27."1.27Effects of aminophylline and enprofylline on the protective activity of phenobarbital against amygdala-kindled seizures in rats. ( Czuczwar, SJ; Jäckel, R; Löscher, W, 1987)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cutrufo, C1
Bortot, L1
Giachetti, A1
Manzini, S1
Dragunow, M1
Persson, CG1
Andersson, KE1
Kjellin, G1
Czuczwar, SJ1
Jäckel, R1
Löscher, W1

Reviews

1 review available for enprofylline and Seizures

ArticleYear
Effects of enprofylline and theophylline may show the role of adenosine.
    Life sciences, 1986, Mar-24, Volume: 38, Issue:12

    Topics: Adenosine; Animals; Asthma; Brain; Bronchodilator Agents; Caffeine; Diuresis; Fatty Acids, Nonesteri

1986

Other Studies

3 other studies available for enprofylline and Seizures

ArticleYear
Differential effects of various xanthines on pentylenetetrazole-induced seizures in rats: an EEG and behavioural study.
    European journal of pharmacology, 1992, Nov-03, Volume: 222, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior,

1992
Adenosine receptor antagonism accounts for the seizure-prolonging effects of aminophylline.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:4

    Topics: Adenosine; Aminophylline; Amygdala; Animals; Brain; Carbolines; Diazepam; Flumazenil; Kindling, Neur

1990
Effects of aminophylline and enprofylline on the protective activity of phenobarbital against amygdala-kindled seizures in rats.
    Epilepsy research, 1987, Volume: 1, Issue:4

    Topics: Aminophylline; Amygdala; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Interactio

1987
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