enprofylline and Seizures
enprofylline has been researched along with Seizures in 4 studies
enprofylline : Xanthine bearing a propyl substituent at position 3. A bronchodilator, it is used for the symptomatic treatment of asthma and chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy.
Seizures: Clinical or subclinical disturbances of cortical function due to a sudden, abnormal, excessive, and disorganized discharge of brain cells. Clinical manifestations include abnormal motor, sensory and psychic phenomena. Recurrent seizures are usually referred to as EPILEPSY or seizure disorder.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"When isbufylline-pretreated rats were challenged with pentylenetetrazole, the EEG was characterized by a short run of wave discharges (whose duration was shorter than that of other groups)." | 5.28 | Differential effects of various xanthines on pentylenetetrazole-induced seizures in rats: an EEG and behavioural study. ( Bortot, L; Cutrufo, C; Giachetti, A; Manzini, S, 1992) |
"Enprofylline, 27." | 5.27 | Effects of aminophylline and enprofylline on the protective activity of phenobarbital against amygdala-kindled seizures in rats. ( Czuczwar, SJ; Jäckel, R; Löscher, W, 1987) |
"The mechanism of action of aminophylline in prolonging seizures was tested in amygdala-kindled rats." | 3.68 | Adenosine receptor antagonism accounts for the seizure-prolonging effects of aminophylline. ( Dragunow, M, 1990) |
"Enprofylline is a more potent smooth muscle relaxant and antiasthmatic drug than theophylline but does not produce, e." | 2.37 | Effects of enprofylline and theophylline may show the role of adenosine. ( Andersson, KE; Kjellin, G; Persson, CG, 1986) |
"When isbufylline-pretreated rats were challenged with pentylenetetrazole, the EEG was characterized by a short run of wave discharges (whose duration was shorter than that of other groups)." | 1.28 | Differential effects of various xanthines on pentylenetetrazole-induced seizures in rats: an EEG and behavioural study. ( Bortot, L; Cutrufo, C; Giachetti, A; Manzini, S, 1992) |
"Enprofylline, 27." | 1.27 | Effects of aminophylline and enprofylline on the protective activity of phenobarbital against amygdala-kindled seizures in rats. ( Czuczwar, SJ; Jäckel, R; Löscher, W, 1987) |
Research
Studies (4)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (50.00) | 18.7374 |
1990's | 2 (50.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Cutrufo, C | 1 |
Bortot, L | 1 |
Giachetti, A | 1 |
Manzini, S | 1 |
Dragunow, M | 1 |
Persson, CG | 1 |
Andersson, KE | 1 |
Kjellin, G | 1 |
Czuczwar, SJ | 1 |
Jäckel, R | 1 |
Löscher, W | 1 |
Reviews
1 review available for enprofylline and Seizures
Article | Year |
---|---|
Effects of enprofylline and theophylline may show the role of adenosine.
Topics: Adenosine; Animals; Asthma; Brain; Bronchodilator Agents; Caffeine; Diuresis; Fatty Acids, Nonesteri | 1986 |
Other Studies
3 other studies available for enprofylline and Seizures
Article | Year |
---|---|
Differential effects of various xanthines on pentylenetetrazole-induced seizures in rats: an EEG and behavioural study.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, | 1992 |
Adenosine receptor antagonism accounts for the seizure-prolonging effects of aminophylline.
Topics: Adenosine; Aminophylline; Amygdala; Animals; Brain; Carbolines; Diazepam; Flumazenil; Kindling, Neur | 1990 |
Effects of aminophylline and enprofylline on the protective activity of phenobarbital against amygdala-kindled seizures in rats.
Topics: Aminophylline; Amygdala; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Interactio | 1987 |