pp242 has been researched along with Seizures* in 1 studies
1 other study(ies) available for pp242 and Seizures
Article | Year |
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Discovery and Preclinical Characterization of 5-[4,6-Bis({3-oxa-8-azabicyclo[3.2.1]octan-8-yl})-1,3,5-triazin-2-yl]-4-(difluoromethyl)pyridin-2-amine (PQR620), a Highly Potent and Selective mTORC1/2 Inhibitor for Cancer and Neurological Disorders.
Topics: Animals; Azabicyclo Compounds; Blood-Brain Barrier; Cell Line, Tumor; Cell Proliferation; Humans; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Mice; Models, Molecular; Phosphatidylinositol 3-Kinases; Protein Conformation; Pyridines; Rats; Seizures; Triazines | 2018 |