Page last updated: 2024-08-17

methaqualone and Seizures

methaqualone has been researched along with Seizures in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199013 (68.42)18.7374
1990's2 (10.53)18.2507
2000's0 (0.00)29.6817
2010's3 (15.79)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Campbell, JA; Greenwood, TD; Rathman, TL; Sleevi, MC; Wolfe, JF1
Blanton, CD; Fatmi, AA; Iturrian, WB; Vaidya, NA1
Blanton, CD; Iturrian, WB; Kite, A; Panos, CH; Vaidya, NA1
El-Azab, AS; Eltahir, KE2
Abou-Krisha, MM; Alhamzani, AG; Jeon, BH; Prashanth, MK; Raghu, MS; Yogesh Kumar, K; Yousef, TA1
Deepakumari, HN; Jayanna, BK; Prashanth, MK; Revanasiddappa, HD; Veeresh, B1
PETRILOWITSCH, N1
Naid, PR; Naik, SR; Sheth, UK1
Jones, BE; Martin, WR; Prada, JA1
Falco, M1
Alpern, HP; Collins, AC; Greer, CA; Olson, RK; Stripling, JS1
Hue, V; Leclerc, F; Martinot, A; Meneguz, C1
Leadbetter, MI; Parmar, SS1
Cowdell, RH; Higgins, G; Sanderson, JH1
Siroky, N1
Bhargava, KP; Saxena, RC; Thacore, VR1
Gagliardi, VJ; Lund, MH; Waggoner, WC; Weaber, TH1
Kohli, RP; Kulshrestha, VK; Singh, N1

Other Studies

19 other study(ies) available for methaqualone and Seizures

ArticleYear
Synthesis and anticonvulsant activity of some new 2-substituted 3-aryl-4(3H)-quinazolinones.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:1

    Topics: Animals; Anticonvulsants; Bicuculline; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Electroshock; Lethal Dose 50; Male; Methaqualone; Mice; Molecular Structure; Pentylenetetrazole; Picrotoxin; Pyridines; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship; Strychnine

1990
Synthesis of previously inaccessible quinazolines and 1,4-benzodiazepines as potential anticonvulsants.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:6

    Topics: Animals; Anticonvulsants; Benzodiazepines; Mice; Pentylenetetrazole; Quinazolines; Receptors, Cell Surface; Receptors, GABA-A; Seizures

1984
Synthesis of 3,4-dihydro-4-oxoquinazoline derivatives as potential anticonvulsants.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:10

    Topics: Animals; Anticonvulsants; Drug Evaluation, Preclinical; Electroshock; Magnetic Resonance Spectroscopy; Male; Mice; Pentylenetetrazole; Quinazolines; Seizures; Spectrophotometry, Infrared; Structure-Activity Relationship

1983
Synthesis and anticonvulsant evaluation of some new 2,3,8-trisubstituted-4(3H)-quinazoline derivatives.
    Bioorganic & medicinal chemistry letters, 2012, Jan-01, Volume: 22, Issue:1

    Topics: Animals; Anticonvulsants; Chemistry, Pharmaceutical; Drug Design; Humans; Male; Methaqualone; Mice; Models, Chemical; Nervous System; Quinazolines; Seizures; Valproic Acid

2012
Design and synthesis of novel 7-aminoquinazoline derivatives: antitumor and anticonvulsant activities.
    Bioorganic & medicinal chemistry letters, 2012, Mar-01, Volume: 22, Issue:5

    Topics: Amines; Animals; Anticonvulsants; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Humans; Mice; Neoplasms; Quinazolines; Seizures

2012
Design, synthesis, molecular docking and pharmacological evaluation of novel triazine-based triazole derivatives as potential anticonvulsant agents.
    Bioorganic & medicinal chemistry letters, 2022, 12-01, Volume: 77

    Topics: Anticonvulsants; Electroshock; Humans; Molecular Docking Simulation; Molecular Structure; Pentylenetetrazole; Seizures; Structure-Activity Relationship; Triazines; Triazoles

2022
Synthesis and Anticonvulsant Activity of N-(Substituted)-1-methyl-2,4-dioxo-1,2-dihydroquinazoline-3(4H)-carboxamides.
    Archiv der Pharmazie, 2016, Volume: 349, Issue:7

    Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Methaqualone; Mice; Pentylenetetrazole; Picrotoxin; Quinazolines; Seizures; Structure-Activity Relationship; Valproic Acid

2016
[THE PROVOCATION OF CONVULSIVE POTENTIALS IN THE ELECTROENCEPHALOGRAM WITH A QUINAZOLONE DERIVATIVE].
    Die Medizinische Welt, 1965, May-01, Volume: 18

    Topics: Electroencephalography; Heterocyclic Compounds; Hypnotics and Sedatives; Mental Disorders; Methaqualone; Pharmacology; Seizures

1965
Involvement of gamma-amino butyric acid (GABA) in the anticonvulsant action of methaqualone.
    Psychopharmacology, 1978, Apr-14, Volume: 57, Issue:1

    Topics: Aminobutyrates; Animals; Anticonvulsants; Brain Chemistry; Cerebellum; Diazepam; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Methaqualone; Muscle Relaxation; Phenobarbital; Rats; Seizures

1978
A method for bioassay of physical dependence on sedative drugs in dog.
    Psychopharmacology, 1976, May-05, Volume: 47, Issue:1

    Topics: Animals; Dogs; Drug Evaluation, Preclinical; Humans; Hypnotics and Sedatives; Methaqualone; Pentobarbital; Psychology, Experimental; Secobarbital; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders

1976
Methaqualone misuse: foreign experience and United States drug control policy.
    The International journal of the addictions, 1976, Volume: 11, Issue:4

    Topics: Aphrodisiacs; Coma; Dose-Response Relationship, Drug; Drug and Narcotic Control; Drug Synergism; Euphoria; Germany, West; Humans; Japan; Methaqualone; Muscle Tonus; Nonprescription Drugs; Seizures; Substance-Related Disorders; United Kingdom; United States

1976
Methaqualone: tolerance and physical dependence in mice.
    Psychopharmacologia, 1975, Nov-21, Volume: 44, Issue:3

    Topics: Animals; Drug Tolerance; Flurothyl; Humans; Male; Methaqualone; Mice; Mice, Inbred C57BL; Myoclonus; Reaction Time; Seizures; Sleep; Substance Withdrawal Syndrome; Substance-Related Disorders

1975
[Antihistamines and antidepressants: poisoning with similar symptoms].
    Presse medicale (Paris, France : 1983), 1990, Oct-27, Volume: 19, Issue:35

    Topics: Arrhythmias, Cardiac; Child, Preschool; Diphenhydramine; Drug Combinations; Humans; Male; Methaqualone; Seizures

1990
Serotonin as a facilitatory neurotransmitter in the anticonvulsant activity of methaqualone.
    Physiology & behavior, 1989, Volume: 46, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Anticonvulsants; Brain; Dose-Response Relationship, Drug; Fenclonine; Male; Methaqualone; Mice; Mice, Inbred Strains; Pentylenetetrazole; Receptors, Serotonin; Seizures; Serotonin; Tryptophan

1989
Fatal poisoning with methaqualone and diphenhydramine.
    Lancet (London, England), 1966, Oct-08, Volume: 2, Issue:7467

    Topics: Diphenhydramine; Female; Humans; Injections, Intramuscular; Methaqualone; Middle Aged; Paraldehyde; Phenytoin; Seizures; Spectrophotometry; Tranquilizing Agents

1966
The management of difficult cases of epilepsy with mandrax.
    The Medical journal of Australia, 1972, May-20, Volume: 1, Issue:21

    Topics: Adolescent; Diphenhydramine; Epilepsy, Tonic-Clonic; Humans; Methaqualone; Seizures

1972
Electroconvulsive therapy with intravenous methaqualone.
    The Indian journal of medical research, 1972, Volume: 60, Issue:9

    Topics: Adolescent; Adult; Cognition Disorders; Electroconvulsive Therapy; Female; Humans; Injections, Intravenous; Male; Methaqualone; Middle Aged; Respiration; Seizures; Succinylcholine; Thiopental

1972
Excessive reaction to methaqualone HCl during bioavailability study.
    Clinical toxicology, 1973, Volume: 6, Issue:3

    Topics: Adult; Biopharmaceutics; Blood Glucose; Calcium; Electrocardiography; Electroencephalography; Epinephrine; Humans; Male; Methaqualone; Oxygen Inhalation Therapy; Respiration; Seizures; Sweating; Time Factors

1973
An experimental investigation of dependence liability of methaqualone in rats.
    Psychopharmacologia, 1974, Mar-09, Volume: 35, Issue:4

    Topics: Acoustic Stimulation; Animals; Body Temperature; Body Weight; Dose-Response Relationship, Drug; Drug Tolerance; Female; Humans; Male; Methaqualone; Motor Activity; Phenobarbital; Rats; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders; Time Factors

1974