Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Reference |
|---|
| "Renal disease and hypertension is a continuing challenge to the nephrologist." | ( Bailey, RR, 1976) |
| "Complications of hypertension are by far the greatese preventable public health problem in many of the developed countries of the world." | ( Mitchell, HC; Pettinger, WA, 1976) |
| "When hypertension is combined with a pronounced cerebral vasodilatation, e." | ( Johansson, BB, 1979) |
| "Intraoperative hypertension is a common problem in patients undergoing myocardial revascularization." | ( Jones, EL; Kaplan, JA, 1979) |
| "Severe hypertension is more likely to occur in the predisposed, and malignant hypertension has been reported." | ( Stokes, GS, 1976) |
| "2." | ( Dal Palù, C; Pagnan, A; Pessina, AC; Thiene, G, 1978) |
| "Cadmium-induced hypertension is not limited to females or to a particular strain." | ( Erlanger, M; Perry, EF; Perry, HM, 1979) |
| "Hypertension is perhaps the most common chronic disease in the United States, if not in the world." | ( Isiadinso, OA, 1979) |
| "The incidence of hypertension is higher in the group that received saline load but the levels of the blood pressure were similar in both groups of hypertensive animals." | ( Arranz, CT; Martinez Seeber, A, 1979) |
| "In MHS the hypertension is more of a systolic type and is of primarily renal origin." | ( Bianchi, G; Folkow, B; Hallbäck, M; Jones, JV, 1977) |
| "Pregnancy-related hypertension is not thought to be an absolute contraindication to glucocorticoid therapy for the induction of pulmonary maturity." | ( Nochimson, DJ; Petrie, RH, 1979) |
| "If renin-dependent hypertension is mediated by angiotensin II, then angiotensin II antagonism should lower blood pressure." | ( Gibney, R; Kirschenbaum, MA; Lifschitz, MD; Rosenblatt, SG, 1978) |
| "Hypertension is an important accelerator of the atherosclerotic process." | ( Clarke, WR; Lauer, RM; Rames, LK, 1978) |
| "Spontaneous hypertension is associated with a relative increase in elastin and decrease in collagen when compared with the normal aorta." | ( Berry, CL; Greenwald, SE, 1978) |
| "Systolic hypertension is difficult to control in the elderly, but this is not an excuse for denying these patients the benefits of carefully controlled antihypertensive treatment, particularly when target organ disease is present." | ( Tarazi, RC, 1978) |
| "Hypertension is a powerful and widespread cardiovascular risk factor, that can be effectively treated, but is still considerably undertreated." | ( Froment, A; Milon, H, 1978) |
| "Usually hypertension is reversible after cessation of therapy with contraceptive steroids." | ( Kaulhausen, H; Klingsiek, L, 1976) |
| "Treatment of hypertension is the first step in the prophylaxis of atherosclerosis." | ( Page, IH, 1977) |
| "(1) This hypertension is genetically transmitted to the offspring in an additive mode by a relatively small number of major genes; (2) Environmental factors such as stress and salt-loading accelerate the hypertension; (3) Parabiosis between SHR and normotensive rats offered no positive evidence indicating the involvement of any strong humoral factors; (4) Assays on adrenal and thyroid hormones have suggested that this hypertension is not a simple endocrine hypertension; (5) The destruction of the central nervous system or sympathectomy on blood pressure or peripheral vascular resistance, as well as the recording of spontaneous sympathetic discharge, etc." | ( Yamori, Y, 1977) |
| "Severe sustained hypertension is the most hazardous component encountered during this reaction." | ( Hranowsky, N; Reece, RW; Texter, JH, 1976) |
| "In SLE, hypertension is not necessarily associated with advanced renal disease, and high blood pressure may occur relatively early in the course of the disease." | ( Budman, DR; Steinberg, AD, 1976) |
| "Low-PRA essential hypertension is usually not a hypervolemic state, but may reflect diminished adrenergic activity, factors associated with aging and effects of a high systemic pressure." | ( Beretta-Piccoli, C; Hirsch, D; Reubi, FC; Weidmann, P; Ziegler, WH, 1976) |
| "Hence, Kyoto hypertension is not supported by a supernormal renin release inherent in the kidney." | ( Johnson, MA; Lange, J; Magraw, S; Tobian, L, 1975) |
| "Hypertension is considered to be the cardiovascular risk factor that is probably most amenable to preventive approaches to public health." | ( Carle, T; Isacsson, SO; Lindell, SE; Malmborg, RO, 1975) |
| "Hypokalemic hypertension is the leading symptome of the disease." | ( Beckerhoff, R; Braun, KP; Furrer, J; Nussberger, J; Pouliadis, G; Siegenthaler, W; Sobbe, A; Vetter, H; Vetter, W; Witassek, F, 1976) |
| "Hypertension is associated with cardiac hypertrophy, which is a structural adaptation of the heart in order to attenuate the systolic stress on the left ventricle." | ( Fernandez-Alfonso, MS; Ganten, D; Paul, M, 1992) |
| "Pregnancy-induced hypertension is a state of marked vasoconstriction, with an enhanced pressor response to angiotensin II." | ( Baker, PN; Broughton Pipkin, F; Kilby, MD, 1992) |
| "Hypertension is more common in condition such as obesity and diabetes mellitus." | ( Pérez-Olea, J, 1992) |
| "Hypertension is an important factor that accelerates deterioration in renal function." | ( Fukuchi, S; Haga, H; Mizuno, K; Takahashi, M; Watanabe, Y, 1992) |
| "Hypertension is an asymptomatic conditions which can be life threatening." | ( Cruikshank, JM; McAinsh, J, 1992) |
| "Hypertension is a known risk factor in the genesis of coronary artery disease." | ( Gupta, KD; Gupta, R; Kasliwal, P, 1992) |
| "Hypertension is observed frequently among pediatric dialysis patients treated with rHuEPO therapy." | ( Ito, K; Komatsu, Y, 1992) |
| "Arterial hypertension is more common in diabetes mellitus than in nondiabetic subjects, and many metabolic and hemodynamic features of diabetes mellitus contribute to the etiology of hypertension." | ( Stern, N; Tuck, ML, 1992) |
| "Essential hypertension is a common human disease believed to result from the interplay of multiple genetic and environmental determinants." | ( Charru, A; Hopkins, PN; Hunt, SC; Jeunemaitre, X; Kotelevtsev, YV; Lalouel, JM; Lifton, RP; Soubrier, F; Williams, CS; Williams, RR, 1992) |
| "Since low renin hypertension is associated with less cardiovascular complications, this may offer an explanation for the better prognosis of hypertension in women." | ( Eide, I; Kjeldsen, SE; Nordby, G; Os, I, 1992) |
| "Hypertension is a frequent complication of chronic renal failure, but its causes are not fully understood." | ( Converse, RL; Cosentino, F; Fouad-Tarazi, F; Jacobsen, TN; Jost, CM; Toto, RD; Victor, RG, 1992) |
| "The development of hypertension is an integral feature of established nephropathy in diabetes, and its amelioration retards the progression of disease and may improve overall mortality." | ( Earle, K; Viberti, GC, 1992) |
| "The pathogenesis of hypertension is due to a variety of causes, including inherited predisposition, dietary habits, especially salt intake, smoking, and also 'general lifestyle'." | ( Rüegg, UT, 1992) |
| "Today, essential hypertension is considered to be genetically closely related to disordered peripheral glucose metabolism, and this situation is described by the term metabolic syndrome." | ( Dotzer, F, 1992) |
| "Hypertension is an important risk factor for cardiovascular disease, which remains the leading cause of death for recipients of renal transplants." | ( Curtis, JJ, 1992) |
| "This form of hypertension is dependent on altered regulation of central pressor mechanisms including the brain renin-angiotensin system." | ( McNeill, JH; Schenk, J, 1992) |
| "Hypertension is a risk factor for coronary atherosclerosis possibly via an adverse effect on the vascular endothelium." | ( Alexander, RW; Ganz, P; Klein, JL; Manoukian, SV; Nabel, EG; Renwick, GH; Selwyn, AP; Treasure, CB; Vita, JA, 1992) |
| "Hypertension is a potential complication following ephedrine and pseudoephedrine overdoses." | ( Burkhart, KK, 1992) |
| "Hypertension is a characteristic feature of GRA." | ( Cook, S; Dluhy, RG; Lifton, RP; Rich, GM; Ulick, S; Wang, JZ, 1992) |
| "Mild hypertension is often associated with other, usually chronic, diseases." | ( Overlack, A; Stumpe, KO, 1992) |
| "Hypertension is known to potentiate the risk of congestive heart failure (CHF) in diabetic individuals." | ( Ganguly, PK; Sahai, A, 1991) |
| "Hypertension is associated with an impairment of endothelium-dependent relaxation." | ( Baumgartner, HR; Clozel, M; Hefti, F; Kuhn, H, 1991) |
| "Essential hypertension is characterized by polygenic inheritance and quantitative and/or qualitative abnormalities of membrane transport systems may function as intermediate phaenotypes." | ( Düsing, R; Göbel, BO; Hoffmann, G; Ruppert, M; Stumpe, KO; Vetter, H, 1991) |
| "1." | ( Duggan, J; Kilfeather, S; Lightman, SL; O'Brien, E; O'Malley, K, 1991) |
| "Aging and hypertension are also associated with an increase in plasma cholesterol and insulin values." | ( Julius, S, 1991) |
| "The control of hypertension is focused primarily in the RAS in the cardiovascular system and the brain." | ( Ferrario, CM, 1990) |
| "Treatment of severe hypertension is beneficial, but reversibility of target-organ damage has not been characterized." | ( Ardeljan, M; Eison, HB; Garbowit, DL; Goldman, ME; Krakoff, LR; Phillips, RA; Shimabukuro, S, 1991) |
| "Arterial hypertension is the most common cause of congestive heart failure and an important risk factor in coronary artery disease (CAD)." | ( Motz, W; Scheler, S; Schwartzkopff, B; Strauer, BE; Vogt, M, 1991) |
| "Hypertension is associated with a rise in arterial pressure and a compensatory increase in cardiac mass, which if not treated effectively, progresses to decompensated congestive heart failure." | ( Cooper, G; Kent, RL; Mann, DL, 1991) |
| "Hypertension is a risk factor for the development of atherosclerosis and its complications, which are among the major causes of morbidity and mortality." | ( Bond, MG; Borhani, NO; Buckalew, V; Canossa-Terris, M; Gibbons, ME; Sowers, JR; Worthy, AJ, 1991) |
| "Hypertension is a known risk factor for atherosclerosis." | ( Fiegel, VD; Knighton, DR; Santilli, SM, 1992) |
| "Arterial hypertension is common after coronary artery-bypass grafting (CABG) surgery and may lead to postoperative complications." | ( de Lange, S; Lawrence, CJ; Lestrade, A, 1991) |
| "Hypertension is an established risk factor for retinopathy." | ( Deckert, T; Feldt-Rasmussen, B; Nørgaard, K, 1991) |
| "Hypertension is associated with an endothelial dysfunction characterized by an increased endothelium-dependent contraction and a decreased endothelium-dependent relaxation." | ( Clozel, M, 1991) |
| "Hypertension is a major risk factor for cardiovascular disease, particularly coronary heart disease." | ( Kannel, WB, 1991) |
| "Because hypertension is a "silent" disease process, compliance with therapy is always a problem." | ( Batts, JM; Branche, GC; Dowdy, VM; Field, LS; Francis, CK, 1991) |
| "Likewise, hypertension is prevalent in obese and diabetic patients." | ( Sowers, JR, 1991) |
| "Arterial hypertension is sustained by either of two long-term mechanisms of arteriolar vasoconstriction or by an inappropriate reaction between them." | ( Laragh, JH; Sealey, JE, 1991) |
| "Hypertension is frequently associated with NIDDM, however the influence of antihypertensive therapy on these combined factors in the diabetic is at present unclear." | ( Elkeles, RS; Feher, MD; Gelding, S; Henderson, AD; Poulter, C; Richmond, W; Sever, PS; Wadsworth, J, 1990) |
| "Hypertension is an important risk factor in hemodialysis patients." | ( Ericsson, F; Kjellstrand, CM; Odar-Cederlöf, I; Thylén, P, 1991) |
| "Hypertension is a chronic problem commonly seen by primary care physicians." | ( Beebe, DK; Blake, GH, 1991) |
| "Hypertension is associated with a variety of disturbances of cell membrane function." | ( Swales, JD, 1990) |
| "This hypertension is characterized by a persistence of increased peripheral resistance, sodium retention, and loss of nocturnal decline in BP." | ( Johnsen, AM; Kormos, RL; McDonald, RH; Nigalye, RL; Rutan, GH; Shapiro, AP; Thompson, ME; Trento, A, 1990) |
| "This type of hypertension is of rapid onset and independent of salt intake; it can be inhibited by glucocorticoid antagonists, such as RU486." | ( Grünfeld, JP, 1990) |
| "Its usefulness in hypertension is well documented, both when used as single drug treatment and in combination with other agents, particularly beta-blockers." | ( Hansson, L, 1990) |
| "Hypertension is often associated to other risk factors, such as abnormal lipid and carbohydrate metabolism, which should be considered for the choice of antihypertensive drug treatment." | ( Buzzaccarini, F; Casolino, P; Giusto, M; Mozzato, MG; Pessina, AC; Rubino, N; Semplicini, A; Serena, L; Valle, R, 1990) |
| "Diabetes-associated hypertension is accompanied by high levels of body sodium and cardiovascular hyper-reactivity to noradrenaline." | ( Antonini, P; Beretta-Piccoli, C; Bernasconi-Zapf, M; Kressebuch, H; Pianezzi, F; Ziegler, WH, 1990) |
| "Renovascular hypertension is potentially curable but of low prevalence." | ( Brown, NL; Bucci, M; Frederickson, ED; Loon, NR; Peterson, JC; Smith, TB; Thompson, RD; Wilcox, CS; Wingo, CS, 1990) |
| "PRIMARY hypertension is a polygenic condition in which blood pressure is enigmatically elevated; it remains a leading cause of cardiovascular disease and death due to cerebral haemorrhage, cardiac failure and kidney disease." | ( Ganten, D; Mullins, JJ; Peters, J, 1990) |
| "Essential hypertension is not a pathophysiologically homogenous disease with respect to reactivity and interaction of plasma catecholamines and PRA." | ( Bultas, J; Jindra, A; Savliková, J, 1990) |
| "Hypertension is a major potential problem among the increasing number of older persons in the population, threatening their health and shortening their life expectancy due particularly to stroke and congestive heart failure (CHF)." | ( Canter, D; Frank, G, 1990) |
| "Arterial hypertension is common in acromegaly, but the pathogenesis of this complication remains unknown." | ( Soszyński, P; Słowińska-Srzednicka, J; Zgliczyński, S, 1990) |
| "In conclusion, hypertension is a common problem in acromegaly and at least in part related to similar risk factors in control populations." | ( Benker, G; Hirche, H; Kraatz, C; Lüdecke, D; Reinwein, D; Weber, F, 1990) |
| "Hypertension is also significantly associated with all-cause mortality in multivariate analysis in both sexes with Type 1 diabetes as proteinuria is in women with Type 2 diabetes." | ( Fuller, JH; Head, J; Jarrett, RJ; Keen, H; Morrish, NJ; Stevens, LK, 1990) |
| "Hypertension is a frequent complication of a scorpion's sting in children, and specific antihypertensive therapy is indicated in severe cases." | ( Gueron, M; Sofer, S, 1990) |
| "Severe experimental hypertension is associated with vascular hyperpermeability and cellular damage in small arteries and arterioles in rats." | ( Wilson, SK, 1990) |
| "Nonmodulating hypertension is characterized, in part, by a decreased aldosterone response to AII, raising the possibility that an increased dopaminergic inhibition of aldosterone secretion underlies the adrenal defect in nonmodulating hypertension." | ( Conlin, PR; Gordon, MS; Hollenberg, NK; Stuenkel, CA; Williams, GH, 1990) |
| "Hypertension is a frequent complication of cyclosporine-induced immunosuppression, but the underlying mechanism is unknown." | ( Hanson, P; Mohanty, PK; Morgan, BJ; Ring, S; Rollins, JA; Scherrer, U; Tindall, RS; Victor, RG; Vissing, SF, 1990) |
| "Essential hypertension is characterized by increased renal vascular resistance, which also has definite implications for renal sodium handling." | ( de Jong, PE; de Zeeuw, D; Navis, GJ, 1986) |
| "Mild hypertension is ubiquitous." | ( Langford, HG, 1989) |
| "In many countries hypertension is the commonest cardiovascular disorder; but communities also exist within many of these countries that do not manifest hypertension." | ( Ikeme, AC, 1989) |
| "Hypertension is frequently present in glomerulonephritis without renal insufficiency but its pathogenesis is poorly understood." | ( Mancini, E; Zuccalà, A; Zucchelli, P, 1989) |
| "Essential hypertension is associated with various cell abnormalities, including alterations in the metabolism of intracellular messengers, such as cytosolic free Ca2+ and cyclic AMP or IP3." | ( Astarie, C; Devynck, MA; Levenson, J; Meyer, P; Simon, A, 1989) |
| "Arterial hypertension is a common side effect of cyclosporine A therapy; however, the cellular mechanism of cyclosporine A-induced hypertension is still unknown." | ( Meyer-Lehnert, H; Schrier, RW, 1989) |
| "1." | ( Antman, KH; Brena, A; Eder, JP; Graves, SW; Peters, WP; Schryber, SM; Sharma, K, 1989) |
| "Essential hypertension is accompanied by several modifications to platelet metabolism suggesting hyper-reactivity to various aggregating agents." | ( Devynck, MA; Le Quan Sang, KH; Mazeaud, MM, 1989) |
| "In the kidney, hypertension is associated with a compensatory shift in the autoregulatory response to pressure." | ( Epstein, M; Hayashi, K; Loutzenhiser, R, 1989) |
| "Hypertension is a pathological condition that involves maternal fetal relationship." | ( Benedetti, G; Biagini, G; Castaldini, C; Cester, N; Damadei, A; Mazzanti, L; Pugnaloni, A; Romanini, C, 1989) |
| "Hypertension is associated with abnormal lipoprotein metabolism, which may be exacerbated by some groups of antihypertensive drugs and represents an additional powerful coronary heart disease risk factor." | ( Bunker, J; Callister, W; Poulter, N; Sever, P; Thom, S; Zographos, D, 1989) |
| "We conclude that hypertension is an important risk factor for renal graft survival, but control of hypertension alone does not appear to improve it." | ( Cheigh, JS; Haschemeyer, RH; Riggio, RR; Rubin, AL; Stenzel, KH; Tapia, L; Wang, JC, 1989) |
| "Hypertension is a complex, heterogeneous disorder of which the exact etiology is unknown." | ( Cameron, EA; Mehta, PJ; Rastogi, SS; Singh, RB, 1989) |
| "In the elderly, hypertension is generally characterized by elevated peripheral vascular resistance and decreased cardiac output." | ( Applegate, WB; Boyd, BK; Sirgo, MA, 1989) |
| "Hypertension is common following coronary artery bypass surgery." | ( Cruise, CJ; David, TE; Marquez-Julio, A; Skrobik, Y; Webster, RE, 1989) |
| "Hypertension is an important risk factor in the progression of renal failure, particularly in patients with pre-existing glomerulopathies such as diabetes and chronic glomerulonephritis." | ( Raij, L; Shultz, PJ; Tolins, JP, 1989) |
| "Hypertension is an early manifestation of autosomal dominant polycystic kidney disease (ADPKD)." | ( Burnett, JC; Offord, KP; Romero, JC; Torres, VE; Wilson, DM, 1989) |
| "The etiology of hypertension is unknown in about 90% of cases." | ( Hermann, U; Kaulich, TW; Schweinsberg, F, 1989) |
| "To evaluate whether hypertension is a cause or just an association with diabetic renal disease, diabetes was induced in both normotensive Wistar-Kyoto and spontaneously hypertensive rats (WKY and SHR)." | ( Allen, TJ; Bach, L; Cooper, ME; Doyle, AE; Jerums, G; Macmillan, P, 1988) |
| "Hypertension is a major health problem for patients over 65 years of age." | ( Nelson, EB; Pool, JL; Taylor, AA, 1988) |
| "Hypertension is associated with increased total peripheral vascular resistance." | ( Alaimo, G; Fasulo, S; Novo, S; Pinto, A; Strano, A, 1985) |
| "Hypertension is also a major risk factor for cardiovascular disease and for accelerated atherosclerosis." | ( Weinberger, MH, 1985) |
| "Although hypertension is the most common and significant risk factor in pregnancy, the risks can be minimized with careful supervision and therapy." | ( Gallery, ED, 1985) |
| "Treatment of hypertension is best accomplished in stepwise fashion, beginning with nondrug therapy followed by a knowledgeable selection of antihypertensive drugs." | ( Moore, MA, 1985) |
| "However, hypertension is more likely to cause cardiovascular disease in those with additional risk factors, such as cigarette smoking, hyperlipidemia, diabetes mellitus, hypokalemia, loft ventricular hypertrophy, or electrocardiographic abnormalities." | ( Weinberger, MH, 1986) |
| "Patients with hypertension are frequently on a number of different anti-hypertensive agents, and if they have other chronic disorders they may take as many as 10 different drugs and up to 40 tablets per day." | ( Morgan, TO; Murphy, J; Nowson, C; Snowden, R, 1986) |
| "Hypertension is the single commonest cause of maternal mortality, but prompt and effective treatment with a variety of drugs, some more familiar than others, can reduce the risk of both maternal and fetal death." | ( Armstrong, P, 1986) |
| "Systemic hypertension is a common clinical problem in the elderly." | ( Gonzalez, DG; Ram, CV, 1987) |
| "1." | ( Levenson, J; Pithois-Merli, I; Simon, AC, 1987) |
| "Pregnancy-induced hypertension is associated with a diminished tissue production of both epoprostenol and E series prostaglandins, and with an enhanced pressor response to AII." | ( Broughton Pipkin, F; Morrison, R; O'Brien, PM, 1985) |
| "Arterial hypertension is by definition a haemodynamic disorder." | ( Messerli, FH; Ventura, HO, 1985) |
| "DOCA-Na hypertension is VP dependent." | ( Fallet, R; Jeffries, WB; Pettinger, WA; Tam, LT; Wang, Y, 1986) |
| "Essential hypertension is a multifactorial disorder mediated by multiple mechanisms." | ( Ram, CV, 1988) |
| "Essential hypertension is a heterogeneous spectrum of pathophysiologic disturbances, not a single entity." | ( Laragh, JH, 1988) |
| "Low birthweight and hypertension are associated." | ( Wynn, A; Wynn, M, 1988) |
| "Paradoxical hypertension is a relatively common complication of surgical repair of coarctation of the aorta." | ( Bojar, RM; Cleveland, RJ; Weiner, B, 1988) |
| "Since hypertension is associated with changes in the handling of various cations (including sodium and lithium) across the cell membrane, the present study investigated the validity of the lithium clearance method in hypertension by comparing two measures of proximal reabsorption." | ( Holstein-Rathlou, NH; Kanters, JK; Leyssac, PP, 1988) |
| "Since hypertension is an important risk factor of cardiovascular morbidity and mortality that can be at least in part decreased by pharmacologic reduction in elevated blood pressure, it is necessary that an antihypertensive agent be effective, but at the same time well tolerated and, according to some recent hypotheses, have no deleterious effect on serum electrolyte levels, as well as lipoprotein and glucose tolerance." | ( Leonetti, G; Rappelli, A; Salvetti, A; Scapellato, L, 1988) |
| "In some whose hypertension is related to activation of the renin-angiotensin-aldosterone control system, appropriate antirenin therapy is effective." | ( Laragh, JH, 1988) |
| "This geriatric hypertension is generally of a salt-sensitive nature with a disproportionate frequency of isolated systolic hypertension." | ( Sowers, JR; Zemel, MB, 1988) |
| "Hypertension is a common complication after renal transplantation and is associated with increased mortality." | ( Arias, M; Chapman, JR; Dunnill, MS; Marcen, R; Morris, PJ; Raine, AE, 1987) |
| "The suggestion that hypertension is more prevalent in renal allograft recipients receiving cyclosporine (CyA), particularly those displaying nephrotoxicity, was tested by reviewing 200 patients' courses, including 92 cadaver (CAD) and 58 living-related (LRD) transplants using CyA and prednisone immunosuppression, and 19 CAD and 31 LRD transplants using azathioprine (Aza) and prednisone, all of whom had at least 1 year posttransplant complete outpatient follow-up." | ( Flechner, SM; Jarowenko, MV; Kahan, BD; Lorber, MI; Van Buren, CT, 1987) |
| "For patients whose hypertension is severe or who have other health problems, antihypertensive drug therapy is also used." | ( Kaplan, NM, 1988) |
| "If hypertension is associated with diabetic nephropathy, our preclinical results suggest that coadministration of sorbinil with antihypertensive therapy may promote a positive synergistic effect further diminishing proteinuria." | ( Beyer-Mears, A; Cruz, E; Del Val, M; Murray, FT, 1988) |
| "Hypertension is common in the elderly and is associated with higher morbidity and mortality, which may be decreased by effective blood pressure control." | ( Dunn, MI; Owens, SD, 1988) |
| "Of course, hypertension is heterogeneous by nature and cannot be attributed solely to any single cause." | ( Mailloux, RJ; Pfeiffer, CC, 1988) |
| "Hypertension is a well-known finding in some patients with neuroblastoma." | ( Beach, B; Feusner, J; O'Leary, M, 1987) |
| "Hypertension is a common feature of end-stage renal disease (ESRD) and constitutes a major risk factor for accelerated cardiovascular disease and premature death." | ( Frohnert, P; Rapaport, FT; Turner, S; Waltzer, WC, 1986) |
| "Essential hypertension is thought to produce a uniform exaggerated natriuresis and diuresis." | ( Epstein, M; Levinson, R; Loutzenhiser, R, 1986) |
| "Essential hypertension is more prevalent and vascular disease more severe in blacks than in whites." | ( Messerli, FH; Ruddel, H; Schmieder, RE, 1986) |
| "Urgent hypertension is defined by severe elevations of blood pressure without associated end-organ damage." | ( Catapano, MS; Marx, JA, 1986) |
| "Treatment of mild hypertension is becoming increasingly accepted, and many more patients are receiving antihypertensive drugs." | ( Rakel, RE, 1987) |
| "Hypertension is a common finding in patients with Cushing's syndrome (CS), but the cause is unknown." | ( Ehlers, ME; Griffing, GT; Melby, JC; Wilson, TE, 1987) |
| "Hypertension is only a component of a multifactorial coronary risk profile which must be considered when implementing optimal therapy." | ( Kannel, WB, 1987) |
| "1." | ( Murray, GE; Nair, R; Patrick, J, 1986) |
| "The paroxysmal hypertension is believed to have resulted from the synergistic effect of the high levels of circulating catecholamines from the tumor and the disruption of autonomic pathways." | ( Agre, JC; Theologides, A; Wilson, BC; Wright, KC, 1986) |
| "Postoperative hypertension is a significant prognostic factor and is associated with an increased incidence of both transient and permanent neurologic deficits." | ( Brown, M; Brown, OW, 1986) |
| "Among complications hypertension is frequent, 53% of patients receiving antihypertensive treatment after 1 year." | ( Beurton, D; Broyer, M; Busson, M; Gagnadoux, MF; Guest, G, 1985) |
| "Secondly, hypertension is a risk factor for premature cardiovascular morbidity and mortality." | ( Egan, B, 1985) |
| "A1-hypertension is attenuated by treatment with an AVP antagonist and is also diminished in rats of the Brattleboro strain." | ( Benarroch, EE; Granata, AR; Imaizumi, T; Reis, DJ; Sved, AF, 1985) |
| "Hypertension is characterized by high levels of circulating and tissue catecholamines; atherosclerosis affects mainly the aorto-iliac tract." | ( Angelini, A; Dal Palù, C; Mazzucato, A; Pagnan, A; Pauletto, P; Pessina, AC; Scannapieco, G; Semplicini, A; Thiene, G; Vescovo, G, 1985) |
| "This hypertension is to a large degree dependent on environmental stimuli, and results chiefly from increase in peripheral resistance." | ( DeMoura, RS; McCubbin, JW; Olmsted, F; Page, IH, 1965) |
| "Angiotensin and hypertension are suggested as among the chief components of such processes." | ( Page, IH, 1972) |
| "Labile hypertension is often associated with elevated cardiac output, increased plasma renin activity (PRA) and urinary cyclic AMP excretion in response to upright posture and to isoproterenol." | ( Boucher, R; Cuche, JL; Genest, J; Hamet, P; Kuchel, O, 1973) |
| "Thus, hypertension is not the result of an absence of beta receptor or a hypersensitivity of the vascular smooth muscle." | ( Brodie, BB; Fleisch, JH; Maling, HM; Spector, S, 1969) |
| "Essential hypertension is the most important cardiovascular disease in black subjects." | ( Aderounmu, AF, 1981) |
| "When DOCA-salt hypertension is induced in the pigeons, the 'initimal cushion' area displays a) accumulation of increasing amounts of cholesteryl esters and b) increase in the synthesis of all prostaglandins (particularly PGE2) from C14-arachidonic acid and c) approaches similarity to the 'lesion area' in the magnitude of these changes." | ( Bale, LK; Deitemeyer, D; Dinh, DM; Kottke, BA; Subbiah, MT, 1981) |
| "Although hypertension is a well-established coronary risk factor, controlled, randomized hypertension drug trials have failed to show a definite preventive effect on the incidence of coronary heart disease." | ( Leren, P, 1984) |
| "The hypertension is renovascular in a number of cases due to ischaemia of the renal cortex." | ( Blétry, O; Godeau, P; Guillevin, L; Leenhardt, A, 1984) |
| "Both age and hypertension are risk factors for the brain." | ( Borzeix, MG; Cahn, J, 1983) |
| "Six women with hypertension are described who developed an immune complex glomerulonephritis after taking 50-300 mg hydralazine daily for 6 months to 7 years." | ( Dowling, JP; Ihle, BU; Kincaid-Smith, P; Whitworth, JA, 1984) |
| "Essential hypertension is the most common disease which develops with advancing age, and its complication, arteriosclerosis, seems to be an exaggerated form of aging process in the mesenchymal tissues." | ( Ooshima, A; Yamori, Y, 1980) |
| "Thus, essential hypertension is combined with a higher beta 2-adrenoceptor density on intact mononuclear cells which might represent, for example, an increased density of prejunctional beta 2-adrenoceptors." | ( Block, LH; Holzgreve, H; Kirzinger, S; Landrock, A; Middeke, M; Remien, J, 1983) |
| "Hypertension is a major risk factor for clinically significant atherosclerotic vascular disease in Western Society, although the link between these conditions remains very poorly understood." | ( Chobanian, AV; Haudenschild, CC; Prescott, MF, 1984) |
| "We suggest that A1 hypertension is predominantly mediated through increased activity of sympathetic vasoconstrictor nerves, and that circulating adrenaline and vasopressin only make a minor contribution to the increase in pressure." | ( Cain, M; Chalmers, J; Kapoor, V; Minson, J, 1984) |
| "Since arterial hypertension is a major risk factor of IHD, the distorted electrolyte composition of our present diet can be considered an important aetiological factor of this disease." | ( Karppanen, H, 1984) |
| "The incidence of hypertension is also found to be higher in females than in males." | ( Rao, RS, 1983) |
| "True refractory hypertension is relatively rare, but the causes of pseudoresistance are many." | ( Tarazi, RC, 1981) |
| "Intracranial hypertension is a complication of hypertensive encephalopathy and may contribute to cerebral injury." | ( Griswold, WR; James, HE; Mendoza, SA; Viney, J, 1981) |
| "Clinical hypertension is to be found in 1-4% of oral contraceptive (OC) users, and it is a major risk in the development of cardiovascular diseases." | ( Weir, RJ, 1982) |
| "Its role in hypertension is unknown." | ( Bariéty, J; Hornych, A; Krief, C; Milliez, P; Safar, M; Simon, A, 1982) |
| "Systolic hypertension is one of the fundamental abnormalities of the cardiovascular system in the elderly." | ( Affrime, MB; Falkner, B; Kim, KE; Lowenthal, DT, 1983) |
| "Hypertension is one of the main cardiovascular risk factors." | ( Eckardt, C; Götze, O; Utermann, D, 1983) |
| "The reduced FAC in hypertension is independent of blood pressure "per se" but may reflect adaptive change in the walls of the large arteries." | ( Bouthier, JE; Laurent, S; Levenson, JA; Safar, ME; Simon, AC, 1983) |
| "Data regarding hypertension are less clear; at present the evidence would suggest that management of mild hypertension following myocardial infarction should give emphasis to sodium restriction and reduction of weight, when appropriate." | ( , 1980) |
| "Essential hypertension is not a disease entity, so therefore it is understood that there are several causes of its development." | ( Koster, M, 1980) |
| "Once hypertension is established the renal nerves do not play a significant role in the maintenance of increased blood pressure." | ( Katholi, RE; Oparil, S; Winternitz, SR, 1980) |
| "Hypertension is an issue of international and national importance." | ( Seedat, YK, 1981) |
| "Hypertension is strictly related to cardiovascular accidents; according to a RCGP study women using OC have 5 times greater risk of death from cardiovascular causes, or 26." | ( Roberts, JM, 1981) |
| "Severe hypertension is rarely seen in children, but there is increasing evidence that childhood may be an appropriate time to consider measures for the prevention of hypertension later in life." | ( Ellison, RC; Gross, DM; Newburger, JW, 1982) |
| "The hypertension is associated with a reduction in PRA and All and therefore is unlikely to be due to hyperactivity of the RAS." | ( Julius, S; Schoeps, P; Shulak, JM; Vander, AJ; Victery, W, 1982) |
| "Hypertension is not simply an acute elevation of arterial pressure during a laboratory experiment." | ( Frohlich, ED, 1982) |
| "The prevelance of hypertension is greater in black than in white populations of the United States, and there is speculation that dietary sodium intake may also be greater in black individuals." | ( Amante, P; Callen, PW; Decker, M; Kerr, GR, 1982) |
| "When hypertension is encountered in a woman receiving estrogens, the ideal 1st step is discontinuation of the estrogen source." | ( Weinberger, MH, 1982) |
| "Essential hypertension is fundamentally a genetic disease which emerges because of environmental impact." | ( Mendlowitz, M, 1982) |
| "Hypertension is more frequent in phenacetin abusers than in controls but is less likely to be due to the analgesic abuse itself than to analgesic nephropathy." | ( Kernen, R; Mihatsch, MJ; Zollinger, HU, 1982) |
| "The crisis of hypertension is always to be regarded as an emergency situation, since always irreversible lesions may be appear on the different organs as a sequel of the permanent vasoconstriction and ischaemia." | ( de Châtel, R, 1980) |
| "Arterial hypertension is a causative factor for BBB disruption, as was seen in the control dogs." | ( Arai, T; Matsuo, S; Nagaro, T; Watanabe, T, 1981) |
| "4." | ( Levenson, JA; Safar, ME; Simon, AC; Temmar, MM; Totomoukouo, JM, 1981) |
| "Arterial hypertension is the factor, stimulating the hypotensive function of IC." | ( Sokolova, RI; Vikhert, AM, 1981) |
| "Whereas hypertension is a risk factor for primary coronary heart disease events, the relative contributions of other risk factors and abnormal responses to symptom-limited maximal exercise are not well-established." | ( Bruce, RA; De Rouen, TA; Hossack, KF, 1980) |
| "Hypertension is observed in 1--2." | ( Mall-Haefeli, M, 1980) |
| "Patients whose hypertension is controlled by nifedipine-PA 10 or 20 mg bid can be successfully converted to nifedipine-GITS with most patients remaining normotensive on 30 mg daily." | ( Myers, MG; Toal, CB, 1995) |
| "Untreated essential hypertension is associated with left ventricular hypertrophy (LVH) and structural changes in resistance vessels." | ( Aalkjaer, C; Holm, M; Lederballe, O; Mulvany, M; Mørn, B; Schroeder, AP; Sihm, I; Thygesen, K, 1995) |
| "In conclusion, hypertension is not causally associated with immune dysfunction as seen in SHR but is related to enhanced NO synthesis in VSMC." | ( Pang, PK; Xiao, J, 1995) |
| "Hypertension is frequently associated with insulin-dependent diabetes mellitus, but the mechanism of the hypertension is unknown." | ( Chen, S; Clough, D; Haddy, FJ; Pamnani, MB; Yuan, C, 1993) |
| "Chronic hypertension is associated with impaired endothelial function [i." | ( Gräser, T; Kauser, K; Rubanyi, GM, 1993) |
| "Chronic hypertension is a major predisposing factor for stroke in humans." | ( Arnal, JF; Blot, S; Gray, F; Michel, JB; Xu, Y, 1994) |
| "Although essential hypertension is usually defined as a hemodynamic disorder, it is expressed differently among individuals and varies during progression of the disease state." | ( Christen, MO; Ollivier, JP, 1994) |
| "Hypertension is common after orthotopic liver transplantation and may be due, in part, to cyclosporin A-induced renal dysfunction and/or enhanced proximal tubular sodium reabsorption." | ( Canzanello, VJ; Krom, RA; Porayko, MK; Schwartz, L; Taler, SJ; Textor, SC; Wiesner, RH; Wilson, DJ, 1995) |
| "Hypertension is a common trait of multifactorial determination imparting an increased risk of myocardial infarction, stroke, and end-stage renal disease." | ( Lifton, RP, 1995) |
| "Hypertension is frequently associated with peripheral insulin resistance." | ( Campbell, IW; Dominiczak, AF; Gould, GW; Livingstone, C, 1995) |
| "Hypertension is a complex disease, the treatment of which should not only lower systolic and diastolic blood pressure but also attenuate the secondary consequences of the disease." | ( Nayler, WG, 1994) |
| "Hypertension is a primary aggravating factor in cerebral infarction." | ( Asanuma, M; Hirata, H; Kondo, Y; Ogawa, N; Tanaka, K, 1995) |
| "Arterial hypertension is a chronic condition regarded as one of the main risk factors for development of coronary atherosclerosis." | ( Circo, A; D'Onofrio, V; Gulizia, M; Platania, F; Rizzini, P; Valenti, R, 1994) |
| "Hypertension is well recognized to be an important cardiovascular risk factor and antihypertensive therapy has been shown to decrease cardiovascular mortality and morbidity as blood pressure control is achieved." | ( Lombardo, D; Raimondi, F, 1994) |
| "Essential hypertension is characterized by skeletal muscle insulin resistance but it is unknown whether insulin resistance also affects heart glucose uptake." | ( Haaparanta, M; Jula, A; Knuuti, MJ; Koivisto, VA; Laine, H; Luotolahti, M; Mäki, M; Nuutila, P; Ruotsalainen, U; Solin, O, 1995) |
| "Because hypertension is a risk factor for stroke, and because severe BP elevation may increase oedema and the risk of haemorrhage, acute antihypertensive therapy might seem reasonable." | ( Garde, E; Jørgensen, HS; Lassen, NA; Olsen, TS, 1995) |
| "Chronic L-NAME hypertension is therefore associated with a selective loss of vascular autoregulation in JMNs, which may contribute to glomerular injury." | ( Bouriquet, N; Casellas, D, 1995) |
| "Arterial hypertension is the leading cause of cardiovascular disease and is associated with an increased risk of stroke and heart attack." | ( Pavan, E; Pessina, AC; Rossi, A; Rossi, G; Sacchetto, A, 1995) |
| "Essential hypertension is characterized by parallel and potentially reversible vascular and cardiac adaptations." | ( Bart, T; Gasser, P; Köhler, M; Martina, B; Weinbacher, M, 1994) |
| "Hypertension is thought to alter many of the functions of the vascular endothelium." | ( Huang, A; Koller, A, 1995) |
| "Hypertension is a potentially life-threatening condition that can lead to heart failure, stroke, and kidney disease." | ( Barry, JM; Bolt, TR; Smith, CJ, 1995) |
| "Hypertension is highly prevalent among African Americans, who are also more likely than whites to develop end-organ complications of hypertension." | ( Burris, JF, 1995) |
| "Arterial hypertension is frequently associated with serum lipid abnormalities." | ( Annuzzi, G; D'Orta, G; Di Marino, L; Ferrara, LA; Lucarelli, C; Mancini, M; Marotta, T; Rossi, F; Russo, O, 1995) |
| "Arterial hypertension is a well known risk factor for atherosclerosis and its complications." | ( Leonetti, G, 1994) |
| "Mild to moderate hypertension is usually asymptomatic and therefore the impact on quality of life and side-effects of the antihypertensive treatment can have a negative effect on treatment compliance." | ( Os, I, 1994) |
| "Hypertension is a major cause of morbidity and mortality in the United States, particularly in the African-American population." | ( Afre, GM; Randall, OS; Retta, TM, 1994) |
| "Hypertension is generally considered a vascular pathologic condition, and most research has been directed towards the influences of hypertension on large peripheral arteries such as the aorta and coronary artery." | ( de Jong, GI; Luiten, PG; Schuurman, T, 1994) |
| "Hypertension is a very common and important disease of modern civilised life." | ( Bakshi, SK; Chawla, KP; Khandekar, RN; Raghunath, R, 1994) |
| "Hypertension is associated with an increased risk of atherosclerosis." | ( Blann, A; Holder, R; Maxwell, SR; Thomason, H; Thorpe, GH; Tse, WY; Waite, M, 1994) |
| "Arterial hypertension is the leading cause of cardiovascular disease in Western countries." | ( Pessina, AC; Rossi, G, 1994) |
| "Hypertension is commonly associated with an endothelial dysfunction that may contribute to the rise in blood pressure." | ( Choi, KC; Kang, YJ; Kim, WJ; Lee, J; Park, JW; Woo, YJ; Yoo, KJ; Yoo, KS, 1994) |
| "Hypertension is a major risk factor for stroke and heart disease in the elderly." | ( Hadley, L; Inch, S; Starr, JM; Whalley, LJ; White, A, 1994) |
| "Although hypertension is a major risk factor in acute myocardial infarction, concomitant hypercoagulability causing thrombosis leading to myocardial infarction remains unproven for lack of an appropriate coagulation test." | ( Lazaro, EJ; Miller, MA; Spillert, CR; Sun, S, 1994) |
| "Hypertension is often related to metabolic disorders, such as android obesity, glucose intolerance, dyslipidemia, and hyperinsulinism (X syndrome)." | ( Boucher, L; Cozic, JA; Gorlier, R; Huin, P; Pettenuzzo-Mollo, M; Provendier, O; Raccah, D; Sicard, J; Vague, P, 1994) |
| "Pathogenesis of hypertension is unknown and investigations should be continued." | ( Szozda, R, 1994) |
| "Essential hypertension is one of the most common diseases that exacerbate the risk of cardiovascular or cerebrovascular attacks." | ( Fujimori, Y; Hanaoka, K; Hayasaka, M; Hiroi, Y; Katoh, H; Kuro-o, M; Miyagishi, A; Nagai, R; Noguchi, T; Takewaki, S, 1995) |
| "Hypertension is common in patients undergoing stress and delayed single-photon emission computed tomography (SPECT) thallium-201 myocardial perfusion imaging." | ( Cecil, MP; Chu, TH; Eisner, RL; Merlino, JD; Patterson, RE; Pilcher, WC, 1994) |
| "Arterial hypertension is a complication of cyclosporine therapy in heart transplant recipients." | ( Lavie, CJ; Messerli, FH; Ochsner, JL; Smart, FW; Stapleton, DD; Valentino, V; Ventura, HO, 1994) |
| "Arterial hypertension is nowadays no longer considered an isolated disorder of blood pressure regulation but a multifactorial disease with metabolic and cellular deviations." | ( Horký, K; Jáchymová, M; Jarolím, M; Jindra, A; Kolár, J; Peleska, J; Savlíková, J; Stolba, P; Umnerová, V; Vorlová, Z, 1994) |
| "Pregnancy-induced hypertension is no uniform disease with one cause and one pathophysiologic course." | ( Brockerhoff, P; Casper, FW; Hroport, M; Schäfer, W; Seufert, RJ; Zahradnik, HP, 1994) |
| "Arterial hypertension is frequently responsible for arteriosclerotic damage in the carotid region." | ( Celentano, A; Ferrara, LA; Gaeta, I; Galderisi, M; Iannuzzi, R; Mancini, M; Marotta, T, 1994) |
| "Hypertension is not yet as important a health problem in rural southern India as it is in westernised societies." | ( Arnold, MJ; Gilberts, EC; Grobbee, DE, 1994) |
| "Hypertension is associated with raised BNP but not CNP plasma levels." | ( Brown, MJ; Cheung, BM, 1994) |
| "Although hypertension is a prevalent condition among the elderly, little is known with respect to the influence of hypertension on oral health and function." | ( Brown, LJ; Ship, JA; Streckfus, CF; Wu, AJ, 1994) |
| "Hypertension is strongly predicted by the combination of low birthweight and a large placenta." | ( Benediktsson, R; Edwards, CR; Lindsay, RS; Noble, J; Seckl, JR, 1993) |
| "Treated hypertension is a weak risk factor for acute myocardial infarction in unselected hypertensive patients." | ( Lindblad, U; Ranstam, J; Råstam, L, 1993) |
| "Hyperactivity and hypertension are both expressed in the SHR." | ( Felder, RA; Hendley, ED; Ohbu, K; Yamaguchi, I, 1993) |
| "In the rat, ACTH hypertension is probably due to corticosterone." | ( Li, M; Martin, A; Whitworth, JA; Wong, KS, 1994) |
| "Hypertension is now a target for genetic studies, and some interesting results have been obtained in humans and in animal models." | ( Soubrier, F, 1993) |
| "Because essential hypertension is a common disorder, its evolutionary advantage in primeval times could rest in skeletal muscle, where higher Ca2+ stores and increased Na+/H+ antiport activity enhanced muscular performance and provided a crucial survival element." | ( Aviv, A, 1994) |
| "Hypertension is a frequent complication after organ transplantation in both children and adults and is a significant risk factor for the development of cardiovascular disease and graft dysfunction." | ( First, MR; Neylan, JF; Rocher, LL; Tejani, A, 1994) |
| "Hypertension is frequently associated with primary hyperparathyroidism, yet the mechanism of such hypertension is unknown." | ( Lewanczuk, RZ; Pang, PK, 1993) |
| "Hypertension is a common feature of both Cushing's syndrome, which is relatively rare, and iatrogenic steroid administration, which is much more common." | ( Whitworth, JA, 1994) |
| "Hypertension is predominantly a disorder of populations in which the fundamental problem is the tendency for blood pressure to rise with age." | ( Perry, IJ; Shaper, AG; Whincup, PH, 1994) |
| "Essential hypertension is characterized by an insulin-resistance state that may be responsible for the increased atherogenesis typical of this disease." | ( Appendino, M; Giorda, C, 1993) |
| "Most cases of hypertension are symptomless--using a therapy which drastically affects a patients food habits is a poor strategy to ensure compliance." | ( Ghooi, RB; Rajarshi, MG; Valanju, VV, 1993) |
| "Hypertension is a major risk factor for stroke and heart disease in elderly people." | ( Starr, JM; Whalley, LJ, 1993) |
| "Hypertension is frequently associated with insulin resistance." | ( Boegehold, MA; Dubey, RK; Kotchen, TA; Reddy, SR; Zhang, HY, 1993) |
| "The hypertension is accompanied by increases in plasma renin activity and can be prevented with intravenous L-arginine administration." | ( Brands, MW; Hu, L; Manning, RD, 1994) |
| "Hypertension is an important factor in cerebral atherosclerosis because of its accelerating effect on the disease." | ( Hollander, W; Kemper, T; Moss, MB; Prusty, S; Rosene, DL, 1993) |
| "Arterial hypertension is the most frequent cause of a disturbance of coronary microcirculation." | ( Motz, W; Strauer, BE; Vogt, M, 1993) |
| "Hypertension is an important contributor to cerebrovascular and cardiovascular morbidity and mortality." | ( Linas, SL; Singh, H, 1993) |
| "Essential hypertension is often associated with high levels of plasma cholesterol or triglycerides." | ( Astarie, C; Devynck, MA; Driss, F; Duranthon, V; Le Quan Sang, KH; Mazeaud, M, 1993) |
| "Hypertension is an additional factor associated with a high degree of renal involvement in IDDM." | ( Düsing, R; Göbel, BO; Hoffmann, G; Mattes, L; Rosskopf, D; Siffert, W; Sorger, M; Vetter, H, 1993) |
| "Hypertension is due to disturbance of the complex interplay between numerous known and unknown mechanisms that normally control blood pressure." | ( Lund-Johansen, P; Omvik, P, 1993) |
| "Hypertension is a major risk factor for the development of heart failure." | ( Altieri, PI; Banchs, HL; González-Fernández, RA; Jiménez, R; Lastra, J; Martínez-Toro, JA; Meléndez, JR, 1993) |
| "Borderline hypertension is thought to be accompanied by increased central nervous system activation, which would predict enhanced anticipation and cortisol secretion in a novel experimental situation." | ( al'Absi, M; Lovallo, WR, 1993) |
| "Hypertension is the most common complication of r-HuEPO therapy in dialysis patients." | ( Baker, LR; Raine, AE; Roger, SD, 1993) |
| "Hypertension is the likely precursive factor in cocaine-induced aneurysmal rupture." | ( Barrow, DL; Colohan, AR; Oyesiku, NM; Reisner, A, 1993) |
| "Essential hypertension is a common occurrence after coronary artery bypass-graft surgery." | ( Chan, E; De Lange, S; Lawrence, CJ; Lestrade, A, 1993) |
| "Hypertension is significantly involved in the progression of diabetic nephropathy and in the development of end stage renal disease in both type I and type II diabetes mellitus." | ( Bollen, CC; Bretzel, RG; Federlin, KF; Maeser, E, 1993) |
| "Hypertension is the leading cause of death in the elderly in Western countries." | ( Bagaglini, E; Bellucci, CR; Cacciafesta, M; De Propris, AM; Del Foco, C; Di Bernardo, MG; Marigliano, V; Scuteri, A, 1993) |
| "Hypertension is the most common side-effect of treatment with recombinant human erythropoietin (EPO) for the anemia of chronic renal failure." | ( Andrew, M; Burwood, R; Cheetham, A; Dallyn, PE; Jones, MA; Kingswood, JC; Sharpstone, P, 1995) |
| "Hypertension is a common multifactorial vascular disorder of largely unknown cause." | ( Lifton, RP, 1996) |
| "Systemic hypertension is common after heart transplantation, and to date there are no randomized, prospective multicenter treatment trials." | ( Bourge, R; Brozena, SC; Clemson, B; Hobbs, R; Johnson, MR; Miller, L; Mills, RM; Naftel, D; Olivari, MT; Quigg, R; Ventura, H, 1996) |
| "Hypertension is associated with impaired cognition, but it is unclear whether this impairment is reversible." | ( Deary, IJ; Starr, JM; Whalley, LJ, 1996) |
| "The treatment of hypertension is not hazardous to cognitive function in older people with pre-existing cognitive impairment." | ( Deary, IJ; Starr, JM; Whalley, LJ, 1996) |
| "Hypertension is associated with an altered design of resistance vessels and decreased endothelium-dependent vasodilator response to acetylcholine." | ( Kiowski, W; Linder, L; Martina, B; Nuesch, R, 1996) |
| "Hypertension is a constituent of the metabolic syndrome, although the rise of the blood sugar does not directly correlate with manifestation of type 2 diabetes, it is a warning that insulin resistance can influence the effectiveness of provisions of the therapeutic regimen, and last not least, also the development of type 2 diabetes." | ( Storková, H; Válek, J; Válková, L, 1996) |
| "Hypertension is one of the major cardiovascular risk factors." | ( Allaert, FA; Barrier, J; Blétry, O; Chamontin, B; Devulder, B; Godeau, P; Godin, M; Guillevin, L; Guilmot, JL; Luccioni, R, 1995) |
| "Hypertension is both an exacerbating factor for, and a consequence of, diabetic renal disease." | ( Leese, GP; Vora, JP, 1996) |
| "While hypertension is a major risk factor for stroke, it is not its sole determinant." | ( Condorelli, G; Ganten, D; Ganten, U; Iaccarino, G; Lindpaintner, K; Rizzoni, D; Rubattu, S; Russo, R; Trimarco, B; Vecchione, C; Volpe, M, 1996) |
| "Hypertension is a multifactorial disorder that results in an increased risk of cardiovascular and end-stage renal disease." | ( Benos, DJ; Berdiev, BK; Bradford, AL; Bubien, JK; Fuller, CM; Ismailov, II; Lifton, RP; Warnock, DG, 1996) |
| "Hypertension is often present in the diabetic individual and it is known to aggravate the vascular complications associated with diabetes." | ( Beenen, OH; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA, 1996) |
| "Since hypertension is more prevalent in primary hyperparathyroidism, intracellular calcium may also be increased in this condition." | ( Fardella, C; Rodriguez-Portales, JA, 1995) |
| "Induced hypertension is one of the few interventions available to reverse acute ischemic neurologic deficit." | ( Chileuitt, L; Leber, K; McCalden, T; Weinstein, PR, 1996) |
| "Arterial hypertension is often associated with plasma volume contraction and hemoconcentration, which negatively affect the vascular flow resistance and microcirculation." | ( Andersson, OK; Bagge, U; Braide, M; Persson, B; Wysocki, M, 1996) |
| "Essential hypertension is a complex polygenetic disorder with different "intermediate phenotypes" among diverse racial/ethnic groups." | ( Douglas, JG; Thibonnier, M; Wright, JT, 1996) |
| "Hypertension is a polygenic disease of world-wide concern." | ( Moskowitz, DW, 1996) |
| "Essential hypertension is characterized by impaired endothelium-dependent vasodilation." | ( Ghiadoni, L; Mattei, P; Salvetti, A; Sudano, I; Taddei, S; Virdis, A, 1996) |
| "Arterial hypertension is a serious and common complication of cyclosporine administration in humans." | ( Matysek, J; Piwowarska, W, 1995) |
| "Resistant hypertension is an important public health problem and a common reason for referral of patients to specialized hypertension clinics." | ( Lewanczuk, RZ; McAlister, FA; Teo, KK, 1996) |
| "Hypertension is more prevalent in blacks than whites, and the reasons for this difference remain unclear." | ( Ergul, A; Ergul, S; Parish, DC; Puett, D, 1996) |
| "Indeed, hypertension is not seen in human cultures with very low salt intake." | ( Kurokawa, K, 1995) |
| "Hypertension is associated with dysfunction of the immune system." | ( Chen, D; Wang, H; Wu, D; Xie, L, 1996) |
| "Maternal hypertension is a common complication of pregnancy and its pathophysiology is poorly understood." | ( Fukamizu, A; Horiguchi, H; Ishida, J; Murakami, K; Sugiyama, F; Takimoto, E, 1996) |
| "Hypertension is a major health problem in Egypt." | ( el-Boghdadly, B; Ibrahim, MM; Zaghloul, SS, 1996) |
| "Hypertension is often cited as a risk factor for erectile dysfunction." | ( Alon, M; Chen, Y; Fischel, B; Jaffe, A; Kisch, ES; Stern, N, 1996) |
| "Hypertension is the predominant factor affecting the visco-elastic properties of large arteries." | ( Barenbrock, M; Hoeks, AP; Kerber, S; Rahn, KH; Spieker, C; Vielhauer, C; Zidek, W, 1995) |
| "Hypertension is commonly associated with diabetes mellitus." | ( Arai, K; Demura, H; Hirose, S; Imaki, T; Muraki, T; Naruse, K; Naruse, M; Seki, T; Tanabe, A; Yoshimoto, T, 1996) |
| "1." | ( Jackson, AA; Langley-Evans, SC; Sherman, RC; Welham, SJ, 1996) |
| "Hypertension is associated with some abnormalities in cell membrane structure, including an impaired distribution of cholesterol into the monolayers of erythrocyte membrane." | ( Montilla, C; Muriana, FJ; Ruíz-Gutiérrez, V; Stiefel, P; Villar, J, 1996) |
| "Hypertension is a major public health problem in India." | ( Wasir, HS, 1996) |
| "Because essential hypertension is reported to be associated with insulin resistance, we studied the mutation in Japanese patients with essential hypertension to clarify associations of this mutation with hypertension, insulin resistance, and basal adrenergic state in hypertensive subjects." | ( Fujisawa, T; Hamada, Y; Higaki, J; Ikegami, H; Kamide, K; Murakami, H; Ogihara, T; Rakugi, H; Shimamoto, K; Yamato, E, 1997) |
| "Arterial hypertension is frequent in liver transplant recipients on cyclosporine A (CsA)." | ( Cherqui, D; Dhumeaux, D; Di Martino, V; Duvoux, C; Fagniez, PL; Lauzet, JY; Métreau, JM; Salvat, A, 1997) |
| "Hypertension is associated with an increased risk of myocardial infarction, and borderline isolated systolic hypertension predicts a possible but more modest increase in risk." | ( Ajani, U; Berger, K; Glynn, RJ; Hennekens, CH; Manson, JE; O'Donnell, CJ; Ridker, PM, 1997) |
| "Hypertension is characterized by a complex mode of inheritance, consisting of the accumulation and interaction of major and minor genes." | ( Matsuo, K; Ohno, Y; Saruta, T; Suzuki, H; Takano, T; Tanase, H, 1997) |
| "Hypertension is one of the major cardiovascular risk factors." | ( Allaert, FA; Barrier, J; Blétry, O; Chamontin, B; Devulder, B; Godeau, P; Godin, M; Guillevin, L; Guilmot, JL; Luccioni, R; Ninet, J; Serise, JM; Zannad, FM, 1996) |
| "As arterial hypertension is frequently associated with diabetes, it is possible that altered intracellular free calcium ([Ca2+]i) handling, as reported in non-insulin-dependent diabetic patients, is accounted for by abnormalities caused by hypertension rather than diabetes." | ( Cipollina, MR; Crepaldi, G; Di Virgilio, F; Duner, E; Nosadini, R; Trevisan, R, 1997) |
| "Hypertension is associated with derangements in glucose and lipid metabolism." | ( Bønaa, KH; Ingebretsen, OC; Jenssen, T; Nordøy, A; Toft, I, 1997) |
| "1." | ( Huggard, PR; Summers, KM; West, J; West, MJ, 1997) |
| "Because this hypertension is remediable by exogenous glucocorticoid, this case was reported to raise attention about treatable aldosteronism." | ( Chien, WY; Hsieh, CJ; Kuo, MC; Liu, JC; Lu, YC; Tung, SC; Wang, PW, 1997) |
| "Essential hypertension is a very common disease in the world." | ( Marzecka, J, 1996) |
| "Hypertension is associated with multiple metabolic and fibrinolytic disturbances that are accentuated in drug-treated hypertensives and already discernible in subjects with borderline hypertension." | ( Asplund, K; Eliasson, M; Jansson, JH; Nilsson, P, 1997) |
| "Hypertension is associated with endothelial dysfunction characterized by decreased endothelium-dependent relaxations and increased endothelium-dependent contractions." | ( Cachofeiro, V; Lahera, V; Maeso, R; Muñoz-García, R; Navarro-Cid, J; Rodrigo, E; Ruilope, LM, 1997) |
| "Diabetes and hypertension are both associated with an increased risk of renal disease." | ( Boston, PC; Hodgson, WC, 1997) |
| "Hypertension is a major risk factor for cardiovascular disease." | ( Dubois, M; Wilson, TW, 1997) |
| "Essential hypertension is a risk factor for cardiovascular disease." | ( Chern, MS; Lin, FC; Wu, D, 1997) |
| "We conclude that hypertension is an important marker of DN progression, and that the more HTM required for control of BP, the faster the decline of renal function." | ( Cheng, SS; Munn, SR; Wilson, DM, 1997) |
| "Human essential hypertension is generally recognized as a multifactorial disease based on genetic diathesis." | ( Fukamizu, A; Sugiyama, F; Taniguchi, K; Yagami, K, 1997) |
| "Obese persons with hypertension are at greater risk for diabetes and hyperlipidemia than normotensive obese persons." | ( Klein, S; Townsend, RR, 1997) |
| "Hypertension is a common and serious complication of autosomal dominant polycystic kidney disease (ADPKD), often occurring early in the disease before the renal function starts to decrease." | ( Strandgaard, S; Wang, D, 1997) |
| "Moderate-to-severe hypertension is less prevalent than mild hypertension, but it is responsible for more incidences of complications." | ( Arocha, I; Arreaza, MR; Bustillo, N; Corral, JL; García, P; López, NC; Perozo, M, 1997) |
| "In particular, hypertension is a strong risk factor in men." | ( Grobbee, DE; Ottervanger, JP; Stricker, BH; Valkenburg, HA, 1997) |
| "Arterial hypertension is the most common chronic medical condition requiring office visits to physicians and is a major contributing factor to the development of myocardial infarction and stroke." | ( Ruilope, LM; Suarez, C, 1997) |
| "Hypertension is a major risk factor for HF and plays a key role in the evolution of the disease." | ( Deedwania, PC, 1997) |
| "Chronic hypertension is associated with structural and functional changes in the cerebrovascular bed, which influence cerebral circulation and its autoregulation." | ( Kagitani, Y; Kawamura, T; Nagai, H; Nakamura, N; Narita, Y; Shinyama, H, 1997) |
| "Hypertension is a significant cause of end-stage renal failure and effective treatment of hypertensive will reduce the progression rate of chronic renal failure in various kidney disorders." | ( Aurell, M; Bengtsson, C; Björck, S, 1997) |
| "Hypertension is an important cause of end-stage renal disease in the black population whilst analgesic nephropathy is important in the white population." | ( Seedat, YK, 1996) |
| "Essential hypertension is characterized by impaired endothelium-dependent vasodilation." | ( Ghiadoni, L; Magagna, A; Salvetti, A; Taddei, S; Uleri, S; Virdis, A, 1997) |
| "Hypertension is a common disorder of multifactorial origin that constitutes a major risk factor for cardiovascular events such as stroke and myocardial infarction." | ( Busch, S; Erbel, R; Horsthemke, B; Jakobs, KH; Moritz, A; Ritz, E; Rosskopf, D; Sharma, AM; Siffert, G; Siffert, W; Wichmann, HE, 1998) |
| "Hypertension is a major risk factor for renal disease and is common in people with diabetes mellitus." | ( Ruilope, LM, 1997) |
| "Hypertension is accompanied by architectural changes in the kidney, heart, and vessels that are often maladaptive and can eventually contribute to end-organ disease such as renal failure, heart failure, and coronary disease." | ( Raij, L, 1998) |
| "Arterial hypertension is commonly observed in orthotopic liver transplantation (OLT) recipients receiving cyclosporin A (CsA), but the precise pathogenetic mechanisms remain partially unknown." | ( Albillos, A; Alvarez-Mon, M; Barrios, C; Cacho, G; Calleja, JL; Cuervas-Mons, V; Daza, R; Escartín, P; Gómez-Arnau, J; Muñoz, J; Pérez-Páramo, M; Rossi, I; Torres, MT, 1998) |
| "Hypertension is a major risk factor for stroke/myocardial infarction as expression of the atherogenic process." | ( Armas de Hernández, MJ; Armas Padilla, MC; Carvajal, AR; Hernández Hernández, R, 1997) |
| "Hypertension is a risk factor which responds well to pharmacologic treatment, and increasing levels of physical activity were proven to decrease CHD risk in numerous studies." | ( Hennekens, CH, 1998) |
| "Because hypertension is associated with an increased incidence of coronary artery disease, this study was designed to determine if coronary vascular contraction to ET-1 is altered in DOCA-salt hypertensive rats and to determine the effect of chronic treatment of DOCA-salt rats with the selective ETA receptor antagonist A-127722." | ( Clarke, N; Fuchs, LC; Giulumian, AD; Pollock, DM, 1998) |
| "Pulmonary hypertension is associated with remodeling of the vessel walls, involving hypertrophy and hyperplasia of pulmonary arterial smooth muscle (PASM) and a concomitant increase in the deposition of connective tissue, resulting in increased wall thickness." | ( Oberlies, NH; Packer, CS; Rhoades, RA; Roepke, JE, 1998) |
| "Essential hypertension is associated with impaired endothelium-dependent vasodilation." | ( Ghiadoni, L; Magagna, A; Salvetti, A; Taddei, S; Virdis, A, 1998) |
| "Hypertension is frequently associated to abdominal obesity, and hyperinsulinism could play a role in its pathogenesis." | ( Avogadri, E; Camanni, F; Ghigo, E; Grottoli, S; Maccario, M; Oleandri, SE; Procopio, M; Rossetto, R, 1998) |
| "Hypertension is often associated with the development of nephroangio- and glomerulo-sclerosis." | ( Ardaillou, R; Boffa, JJ; Chatziantoniou, C; Dussaule, JC, 1998) |
| "Hypertension is a common multifactorial disorder associated with considerable morbidity and mortality." | ( Houtman, P; Jackson, SN; Trembath, RC; Williams, B, 1998) |
| "Additionally, hypertension is associated with increased body weight in cyclosporine-treated patients and with more severe renal dysfunction in patients receiving tacrolimus." | ( Canzanello, VJ; Krom, RA; Porayko, MK; Schwartz, LL; Taler, SJ; Textor, SC; Wiesner, RH, 1998) |
| "Arterial hypertension is associated with marked changes in the structure of both resistance and large arteries." | ( Levy, BI, 1998) |
| "Genetic hypertension is associated with an apparent endothelial dysfunction and impaired endothelium-dependent vasodilatation in response to increased flow and receptor-dependent agonists." | ( Bauersachs, J; Bouloumié, A; Busse, R; Fleming, I; Mülsch, A; Wiemer, G, 1998) |
| "Hypertension is a known risk factor for the development of atherosclerosis." | ( Keidar, S, 1998) |
| "We suggest that hypertension is associated with a reduced activity of the sGC/cGMP-system in the vasculature but not in the heart muscle." | ( Hacker, A; Kojda, G; Kottenberg, K; Noack, E, 1998) |
| "Essential hypertension is associated with greater than normal lipoperoxidation and an imbalance in anti-oxidant status, suggesting that oxidative stress is important in the pathogenesis of essential hypertension or in arterial damage related to essential hypertension." | ( Corrocher, R; Faccini, G; Girelli, D; Lombardi, S; Olivieri, O; Russo, C; Zenari, ML, 1998) |
| "Primary hypertension is characterized by preferential activation of the cardiac, skeletal muscle and renal sympathetic outflow particularly in younger patients." | ( Jennings, GL, 1998) |
| "Nephrotoxicity and hypertension are the major secondary effects of cyclosporine." | ( Bagnis, C; Deray, G, 1998) |
| "Essential hypertension is a major Public Health issue." | ( Julius, S; Mann, J, 1998) |
| "Hypertension is one of the adverse effects associated with recombinant human erythropoietin (rHuEPO) therapy for anaemia in hemodialysed patients." | ( Azzadin, A; Buczko, W, 1998) |
| "Thus, DOCA-salt hypertension is associated with altered morphology of the small-arterial wall, without altering stiffness of the arterial wall components." | ( He, G; Intengan, HD; Schiffrin, EL, 1998) |
| "Hypertension is a prevalent disease among African Americans, and successful treatment rates are low." | ( Flack, JM; Hall, WD; Preisser, J; Reed, JW; Yunis, C, 1998) |
| "Essential hypertension is characterized by an impairment of endothelium-dependent vasodilatation." | ( Ghiadoni, L; Mattei, P; Salvetti, A; Taddei, S; Virdis, A, 1998) |
| "Hypertension is defined as a disease of elevated systolic and diastolic blood pressure and consequently the goals of treating hypertension have been simply to normalize the blood pressure." | ( Neutel, JM; Smith, DH, 1998) |
| "2." | ( Kelly, JJ; Mangos, G; Whitworth, JA; Williamson, PM, 1998) |
| "Salt-sensitive hypertension is characterized by a cluster of renal, hormonal, and metabolic derangements that might favor the development of cardiovascular and renal damage." | ( Bellini, C; Cicogna, S; De Siati, L; Desideri, G; Ferri, C; Giuliani, E; Santucci, A, 1998) |
| "Hypertension is reported to be one of the most common causes of end-stage renal disease (ESRD) in Europe and in the United States." | ( Andersson, OK; Ljungman, S; Siewert-Delle, A; Wilhelmsen, L, 1998) |
| "Cyclosporin-induced hypertension is a major complication of immunosuppression in transplant recipients but its pathophysiology is only partly understood." | ( Bartholomeusz, B; Hardy, KJ; Nelson, AS; Phillips, PA, 1998) |
| "Hypertension is a major risk factor for premature death." | ( Burden, AC, 1998) |
| "Hypertension is common in West Africa and likely to become more common as urbanisation increases." | ( Acheampong, JW; Cappuccio, FP; Eastwood, JB; Phillips, R; Plange-Rhule, J; Saggar-Malik, AK, 1999) |
| "Low-renin hypertension is characterized by a high ratio of aldosterone to plasma renin activity (ALD/PRA), which may suggest inappropriately increased aldosterone biosynthesis." | ( Iwai, N; Kinoshita, M; Tamaki, S; Tsujita, Y, 1999) |
| "Because essential hypertension is partly genetic, it is possible that altered control of aldosterone synthase gene expression or translation may be responsible." | ( Anderson, NH; Connell, JM; Davies, E; Fraser, R; Friel, EC; Holloway, CD; Inglis, GC; Ingram, MC; Morrison, C, 1999) |
| "Hypertension is a recognized marker of poor prognosis in IgA nephropathy." | ( Csiky, B; Kovács, T; Nagy, J; Vass, T; Wágner, L, 1999) |
| "Renal parenchymal hypertension is defined as hypertension caused by disease of the kidneys." | ( Fernandez, L; Preston, RA, 1998) |
| "Hypertension is an important clinical problem and is often accompanied by left ventricular (LV) hypertrophy and dysfunction." | ( Beyerbacht, HP; de Roos, A; Doornbos, J; Lamb, HJ; Stoel, BC; van der Laarse, A; van der Wall, EE, 1999) |
| "Liquorice-induced hypertension is an example of an acquired defect in dehydrogenase activity of 11 beta HSD, caused by glycyrrhetinic acid." | ( Dullaart, RP; Kerstens, MN, 1999) |
| "The insight that hypertension is often just one of the components of the so-called metabolic syndrome suggests that a modern antihypertensive drug should not only lower blood pressure; to exert optimal cardioprotective properties it should also have a neutral or even positive metabolic profile as regards its effects on lipids, glucose and insulin in order to achieve a better protection against CHD." | ( Hansson, L, 1998) |
| "Hypertension is elicited by chronic, low dose intracerebroventricular (ICV) angiotensin II (AII) infusion in rats raised from weaning on relatively high sodium chloride diet (250 mEq kg(-1) food)." | ( Camara, AK; Osborn, JL, 1999) |
| "Hypertension is probably a polygenic disease, with several abnomalies in these systems interacting with a particular environment." | ( Anglicheau, D; Grünfeld, JP; Joly, D, 1999) |
| "Hypertension is a common concomitant condition in renal transplant recipients." | ( Bölscher, S; Geiger, H; Kachel, HG; Lenz, T; Peschke, B; Scheuermann, EH, 1999) |
| "Essential hypertension is associated with an increased incidence of insulin resistance of skeletal muscle glucose transport." | ( Dietze, GJ; Fogt, DL; Henriksen, EJ; Jacob, S, 1999) |
| "1." | ( Hutri-Kähönen, N; Kähönen, M; Nordback, I; Pörsti, I; Sand, J; Taurio, J; Wu, X, 1999) |
| "Antecedent hypertension is not a significant prognosticator in patients with AMI and clinical heart failure given ACE inhibitor therapy." | ( Ball, S; Hall, A; Spargias, K, 1999) |
| "Arterial hypertension is associated with structural and functional alterations of the vessel walls." | ( Kochar, MS; Mazur, LI; Patel, A, 1999) |
| "Systolic hypertension is a major risk factor for cardiovascular disease." | ( Brooks, DP; Ruffolo, RR, 1999) |
| "Hypertension is one of the most important risk factors for cardiovascular morbidity and mortality." | ( Doolman, R; Grossman, E; Nussinovitch, N; Rachima-Maoz, C; Rosenthal, T; Sela, B; Sharabi, Y, 1999) |
| "Essential hypertension is a widespread multifactorial pathology which is probably controlled by numerous genes." | ( Chistiakov, DA; Turakulov, RI, 1999) |
| "Hypertension is also associated with increased risk of sudden death, particularly in those with left ventricular hypertrophy (LVH)." | ( Evans, S; James, M; Jones, J; Saadeh, A, 1999) |
| "Hypertension is associated with structural and mechanical abnormalities of resistance arteries." | ( Intengan, HD; Park, JB; Schiffrin, EL, 1999) |
| "Pregnancy-induced hypertension is associated with increased vascular resistance; however, the cellular mechanisms involved are unclear." | ( Alexander, BT; Granger, JP; Kanashiro, CA; Khalil, RA, 1999) |
| "Hypertension is a side effect of systemically administered glucocorticoids, but the underlying molecular mechanism remains poorly understood." | ( Förstermann, U; Kleinert, H; Lehr, HA; Lemmer, B; Prellwitz, W; Schäfer, SC; Schwarz, PM; Wallerath, T; Witte, K; Wohlfart, P, 1999) |
| "Hypertension is common after renal transplantation." | ( Calviño, J; Lens, XM; Romero, R; Sánchez-Guisande, D, 2000) |
| "Pregnancy-induced hypertension is associated with low calcium levels in the diet, improving with the treatment of calcium supplements." | ( Ramón de Berrazueta, J, 1999) |
| "Arterial hypertension is a cardinal precursor of congestive heart failure, and diastolic dysfunction is the most frequent mechanism for it." | ( Anguita Sánchez, M, 1999) |
| "Diabetes and hypertension are the leading causes of end-stage renal disease in the Western world." | ( Weir, MR, 1999) |
| "Tobacco smoking and hypertension are the two most important risk factors for coronary heart disease and stroke." | ( Pandey, MR, 1999) |
| "Hypertension is frequently associated with insulin resistance and enhanced sympathetic activity supposedly mediated by an effect of the hormone on the hypothalamus." | ( Colangelo, V; Di Grezia, R; Lembo, G; Morisco, C; Orzi, F, 2000) |
| "Essential hypertension is an arbitrarily defined disorder to which both genetic and environmental factors contribute." | ( Jyothy, A; Rao, VB; Reddy, PP; Sudhakar, K; Sujatha, M, 1999) |
| "Patients with hypertension are at increased risk of developing heart failure (HF), but the mechanisms by which hypertension leads to HF have not been clarified [although left ventricular hypertrophy (LVH) is clearly a predictor of an increased risk of HF]." | ( Cleland, JG, 1999) |
| "Borderline hypertension is often the initial stage of stabilized hypertension." | ( Pacini, G; Piccardo, MG; Rosa, MS; Turchetti, G, 1999) |
| "If hypertension is secondary to chronic renal failure of any etiology, it can be recognized from biochemical assays for blood urea nitrogen and creatinine." | ( Campese, VM; Nosrati, S, 1999) |
| "Essential hypertension is a complex disease influenced by different genetic and environmental factors." | ( Brand, E; Ringel, J; Sharma, AM, 2000) |
| "At present arterial hypertension is considered a social disease as it poses great health, economic and social problems." | ( Calanna, A; Luca, S; Terranova, R, 1999) |
| "Hypertension is a known risk factor for cardiovascular disease, but few epidemiological studies have examined simultaneously the effect of baseline blood pressure on the development of stroke, acute myocardial infarction (AMI), and end-stage renal disease (ESRD)." | ( Fukiyama, K; Ikemiya, Y; Iseki, K; Kimura, Y; Muratani, H; Okumura, K; Wakugami, K, 2000) |
| "Hypertension is extremely prevalent after renal transplantation, affecting up to 70% of all patients." | ( Mayer, G; Rosenkranz, AR, 2000) |
| "Hypertension is associated with a significantly increased risk of morbidity and mortality." | ( , 2000) |
| "This NO-deficient hypertension is associated with the development of concentric LVH, myocardial fibrosis and protein remodeling of the left ventricle." | ( Simko, F; Simko, J, 2000) |
| "Subjects with hypertension are hyperinsulinemic and resistant to insulin-stimulated glucose uptake." | ( Gonzalez, R; Grinsell, JW; Lardinois, CK; Michaels, JR; Sare, JS; Starich, GH; Swislocki, A, 2000) |
| "The prevalence of hypertension is greater among the African-American population, with a distressingly high rate of end-organ complications." | ( Kodali, P; Meggs, LG, 1999) |
| "Systemic hypertension is common in individuals with non-insulin-dependent diabetes (NIDD) and, in this population, markedly increases the risk for cardiovascular complications." | ( Mozaffari, MS; Patel, C; Schaffer, SW; Warren, BK, 2000) |
| "The hypertension is associated with total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and low density lipoprotein TG (LDL-TG), while overweight is related with TG and high density lipoprotein cholesterol (HDL-C), effecting significantly on very low density lipoprotein TG (VLDL-TG)." | ( Deyanov, C; Vangelova, K, 2000) |
| "Hypertension is associated with insulin resistance and hyperinsulinemia." | ( Kawasaki, H; Kuroda, S; Mimaki, Y, 2000) |
| "Hypertension is a major independent risk factor for cardiac deaths, and diastolic dysfunction is a usual finding during the course of this disease." | ( Aksoy, FG; Garcia, MJ; Muderrisoglu, H; Sabah, I; Thomas, JD; Yalçin, F, 2000) |
| "Because hypertension is less severe in female than male DOCA rats, we hypothesized that female DOCA rats would display attenuated ET(B) vasoconstrictor responses." | ( Catelli De Carvalho, MH; David, FL; Fortes, ZB; Nigro, D; Scivoletto, R; Tostes Passaglia, RC, 2000) |
| "Severe hypertension is a common clinical problem in the United States, encountered in various clinical settings." | ( Marik, PE; Varon, J, 2000) |
| "Hypertension is a frequent complication in diabetes, and microalbuminuria has become an essential index of cardiovascular prognosis in type 2 diabetics." | ( Bauduceau, B; Dupuy, O; Mayaudon, H, 2000) |
| "Essential hypertension is often accompanied by abnormalities of the coagulation/fibrinolytic system, predisposing to a procoagulant state." | ( Hatzizacharias, AN; Krespi, PG; Kyriakidis, MK; Makris, TK; Stavroulakis, GA; Triposkiadis, FK; Tsoukala, CG; Votteas, VV, 2000) |
| "Hypertension is frequently accompanied by left ventricular hypertrophy, endothelial dysfunction, and abnormal glucose metabolism." | ( Abe, M; Doba, N; Kimura, Y; Kinouchi, T; Kushiro, T; Kuwabara, Y; Kuwata, S; Okazaki, R; Tomiyama, H; Yoshida, H, 2000) |
| "Essential hypertension is a pathological condition characterized by endothelial dysfunction." | ( Ghiadoni, L; Salvetti, A; Taddei, S; Virdis, A, 2000) |
| "Essential hypertension is associated with impaired endothelium-dependent vasodilation and is caused mainly by production of oxygen free radicals that can destroy nitric oxide (NO), impairing its beneficial and protective effects on the vessel wall." | ( Ghiadoni, L; Salvetti, A; Sudano, I; Taddei, S; Virdis, A, 2000) |
| "Hypertension is prevalent world-wide, and it affects over 50 million individuals in the United States alone." | ( August, P; Leventhal, B; Suthanthiran, M, 2000) |
| "Hypertension is one of the most prevalent and powerful contributors to atherosclerotic cardiovascular disease." | ( Harrison-Bernard, LM; Raij, L, 2000) |
| "Essential hypertension is an insidious disease in which the afflicted person risks disability and death from myocardial infarction and stroke." | ( Lake-Bruse, KD; Sigmund, CD, 2000) |
| "Hypertension is associated with alterations in the structure, function, and mechanical properties of large and small arteries." | ( Park, JB; Schiffrin, EL, 2000) |
| "Hypertension is a prevalent health problem and a major cause of morbidity and mortality in the United States." | ( Bivalacqua, TJ; Champion, HC; Hugghins, SY; Shah, MK, 2000) |
| "Hypertension is a very prevalent cardiovascular (CV) disease risk factor in developed countries." | ( Brown, MD; Hagberg, JM; Park, JJ, 2000) |
| "Hypertension is confirmed when BP measured on three separate occasions over 1-2 weeks and when consistently it is raised above 140/90 mm Hg." | ( Arya, SN, 2000) |
| "Arthritis and hypertension are frequent comorbidities in the elderly hypertensive population." | ( Anderson, A; Bertram, D; Morgan, TO, 2000) |
| "Hypertension is usually diagnosed by means of casual office BP readings." | ( Cassimjee, MH; Pillay, BJ; Rugnath, T, 2000) |
| "White coat hypertension is common in patients diagnosed as having mild to moderate hypertension by means of casual BP readings." | ( Cassimjee, MH; Pillay, BJ; Rugnath, T, 2000) |
| "Human essential hypertension is a complex trait with poorly understood genetic determination." | ( Henry, RR; Kailasam, MT; O'Connor, DT; Parmer, RJ; Tyrell, EA, 2000) |
| "Hypertension is a prominent feature of patients with Cushing's disease and ectopic adrenocorticotropic hormone (ACTH) syndrome, who have elevated ACTH levels." | ( Hatakeyama, H; Inaba, S; Miyamori, I; Taniguchi, N, 2000) |
| "Hypertension is a major side effect of cyclosporin (CsA)." | ( Antonello, A; Bonvicini, P; Calò, L; Cantaro, S; D'Angelo, A; Davis, PA; Livi, U; Rigotti, P; Semplicini, A, 2000) |
| "DOCA-salt hypertension is associated with alterations in coronary reactivity." | ( de Champlain, J; Lamontagne, D; Millette, E, 2000) |
| "Hypertension is an important risk factor for renal injury." | ( Joles, JA; Koomans, HA; Verhagen, AM, 2001) |
| "Treatment of hypertension is necessary to prevent morbidity i." | ( Patel, JC, 2000) |
| "Hypertension is associated with low plasma ascorbic acid levels and impaired endothelial function." | ( Biegelsen, ES; Duffy, SJ; Gokce, N; Holbrook, M; Huang, A; Hunter, LM; Keaney, JF; Vita, JA, 2001) |
| "Hypertension is a common finding in patients > or =65 years of age that contributes to cardiovascular morbidity and mortality, but many patients are untreated or their hypertension inadequately controlled." | ( Langdon, C, 2000) |
| "Gene therapy for hypertension is very important for the next generation of antihypertensive drugs." | ( Shibuya, K; Tamura, K; Tokita, Y; Tsurumi, Y; Umemura, S, 2001) |
| "Gestational hypertension is a multisystem disorder which always resolves itself after delivery; its primary pathology still remains incompletely clarified." | ( Creatsas, G; Elsheikh, A; Loutradis, D; Mastorakos, G; Michalas, S; Milingos, S, 2001) |
| "Apparently, when hypertension is sustained, reappearance of target organ damage may not be entirely dependent on angiotensin." | ( Blezer, EL; Joles, JA; Koomans, HA; Nicolay, K, 2001) |
| "Salt-sensitive hypertension is common in people of African origin, and may be caused by increased transepithelial sodium absorption." | ( Baker, EH; Ireson, NJ; MacGregor, GA; Tait, JS, 2001) |
| "Hypertension is a debilitating disease with significant socioeconomic and emotional impact." | ( Francis, SC; Gelband, CH; Huentelman, MJ; Katovich, MJ; Pachori, AS; Raizada, MK, 2001) |
| "Both menopause and hypertension are associated with endothelial dysfunction and are risk factors for coronary heart disease." | ( Chayama, K; Goto, C; Higashi, Y; Matsuura, H; Nakagawa, K; Ohama, K; Oshima, T; Sanada, M; Sasaki, S, 2001) |
| "Essential hypertension is associated with impaired endothelium-dependent vasodilation caused by oxygen free radical-induced nitric oxide (NO) breakdown." | ( Favilla, S; Ghiadoni, L; Magagna, A; Pompella, A; Salvetti, A; Taddei, S; Virdis, A, 2001) |
| "The hypertension is only one manifestation of an underlying multifactorial, multisystem disorder, initiated early in pregnancy." | ( Bolte, AC; Dekker, GA; van Geijn, HP, 2001) |
| "Hypertension is associated with increased urinary calcium excretion (UCa)." | ( Blackwood, AM; Cappuccio, FP; Cook, DG; Sagnella, GA, 2001) |
| "Hypertension is a leading cause of cardiovascular, cerebral, and renal disease morbidity and mortality." | ( Adas, F; Breyer, MD; Capdevila, JH; Falck, JR; Holla, VR; Imig, JD; Keeney, DS; Kovacs, WJ; Magnuson, MA; Olsen, N; Price, E; Waterman, MR; Zhao, X, 2001) |
| "Hypertension is another predictor of erectile dysfunction (ED)." | ( Khan, MA; Mikhailidis, DP; Milionis, HJ; Morgan, RJ, 2000) |
| "Hypertension is associated with a number of adverse morphologic and functional changes in the cardiovascular system." | ( Williams, B, 2001) |
| "Hypertension is the main cause of stroke that represents the second most common cause of death in the industrialized world and a leading cause of inability of the elderly." | ( Amenta, F; Sabbatini, M; Tomassoni, D, 2001) |
| "Thus, salt-induced hypertension is associated with a reduction in levels of nitric oxide regardless of gender." | ( Bayorh, MA; Eatman, D; Socci, RR; Thierry-Palmer, M; Wang, M, 2001) |
| "Hypertension is highly prevalent after renal transplantation and has been associated with lower graft survival." | ( Anaya, F; Del Castillo, D; Holgado, R, 2001) |
| "Hypertension is a major cardiovascular risk factor in the development of coronary artery disease (CAD); therefore, evaluating the presence of CAD is a primary clinical goal." | ( Agricola, E; Ammaturo, T; Ballo, P; Barbati, R; Focardi, M; Guerrini, F; Mondillo, S; Nami, R; Picchi, A, 2001) |
| "Hypertension is an important risk factor for chronic transplant nephropathy." | ( Boots, JM; Christiaans, MH; Kooman, JP; Leunissen, KM; van Der Sande, FM; van Hooff, JP, 2001) |
| "Essential hypertension is a multifactorial disease which is evoked by multiple environmental and genetic factors." | ( Higaki, J; Katsuya, T; Ogihara, T, 2001) |
| "In addition, the hypertension is known to increase the rate of hyperuricemia." | ( Saito, Y; Tatsuno, I, 2001) |
| "Hypertension is a major risk factor for progressive renal disease." | ( Epstein, M, 2001) |
| "Although hypertension is an important risk factor for the development of atherosclerosis, the mechanisms for this interaction are incompletely described." | ( Aikawa, M; Hill, CC; Lee, RT; Libby, P; Sakamoto, H; Taylor, WR; Weiss, D, 2001) |
| "Hypertension is a risk factor for the development of end-stage renal disease." | ( Loscalzo, J; Rudd, MA; Trolliet, MR, 2001) |
| "Arterial hypertension is a major risk factor for microangiopathic diabetic complications and associated with an increased cardiovascular morbidity and mortality." | ( Schernthaner, G; Schnack, C, 2001) |
| "Hypertension is a widespread entity in the surgical intensive care unit." | ( Porter, JM; Sipe, EK; Trienski, TL, 2001) |
| "Hypertension is common in type 2 diabetic patients and is associated with a high mortality." | ( Hara, M; Katsuragi, I; Nakagawa, M; Okeda, T; Ooie, T; Saikawa, T; Sakata, T; Sakino, H; Shigematsu, S; Takahashi, N; Yoshimatsu, H; Yufu, K, 2001) |
| "Salt-sensitive hypertension is more common and has more severe consequences in urban black populations than in white populations." | ( Baker, EH; Carney, C; Ireson, NJ; MacGregor, GA; Markandu, ND, 2001) |
| "Control of hypertension is hindered by the incidence of adverse events associated with therapy, which can result in low patient compliance." | ( Levine, B, 2001) |
| "Pregnancy-induced hypertension is characterized by an increased sympathetic activity and probably by a decreased synthesis/activity of nitric oxide." | ( Benchetrit, S; Bernheim, J; Green, J; Katz, B; Podjarny, E, 2001) |
| "Essential hypertension is associated with impaired endothelium-dependent vasodilation caused by oxygen free radical-induced nitric oxide (NO) breakdown." | ( Cominacini, L; Garbin, U; Ghiadoni, L; Magagna, A; Pasini, AF; Salvetti, A; Taddei, S; Virdis, A, 2001) |
| "Secondary hypertension is often characterized by loss of diurnal blood pressure variability." | ( Fraser, TB; Mangos, GJ; Turner, SW; Whitworth, JA, 2001) |
| "Hypertension is present earlier in life than signs of glomerular disease, which suggests that hypertension is a major contributor to rather than primarily resulting from onset of renal disease." | ( Rasch, R; Weeks, DA; Woods, LL, 2001) |
| "Malignant hypertension is a serious form of arterial hypertension in which the physiopathological mechanisms include increased activity of the sympathetic nervous system, renin angiotensin system, and endothelium dysfunction." | ( Bortolotto, LA; Kamitsuji, CS; Krieger, EM; Lopes, HF; Szlejf, C, 2001) |
| "Hypertension is one of the major side effects of recombinant human erythropoietin (rHuEPO) therapy." | ( Hörl, WH; Sunder-Plassmann, G, 2001) |
| "Most forms of hypertension are associated with a wide variety of functional changes in the hypothalamus." | ( de Wardener, HE, 2001) |
| "Hypertension is also significantly associated with reduced graft survival and thereby requires aggressive treatment intervention." | ( Koomans, HA; Ligtenberg, G, 2001) |
| "Hypertension is the main risk factor for cerebrovascular disease including vascular dementia and control of blood pressure might protect from lesions causing cognitive impairment." | ( Amenta, F; Sabbatini, M; Tomassoni, D, 2001) |
| "Lead (Pb)-induced hypertension is characterized by an increase in reactive oxygen species (ROS) and a decrease in nitric oxide (NO)." | ( Cordellini, S; Malvezzi, CK; Moreira, EG; Vassilieff, I; Vassilieff, VS, 2001) |
| "Hypertension is an important risk factor for erectile dysfunction (ED)." | ( Erdmann, E; Rosenkranz, S, 2001) |
| "Hypertension is one of the most important risk factors for ischaemic heart disease and stroke." | ( Franczuk, P; Janicki, K; Pieniazek, W, 2001) |
| "Hypertension is significantly delayed in females with functional ovaries." | ( Barnard, RJ; Roberts, CK; Vaziri, ND, 2001) |
| "Hypertension is not required for the accelerated atherosclerosis seen in apoE/eNOS DKO animals, and control of hypertension during a 16-week period does not prevent aortic aneurysm formation." | ( Astern, J; Chen, J; Gyurko, R; Huang, PL; Kuhlencordt, PJ, 2001) |
| "Hypertension is an important cardiovascular risk factor and the goal of its pharmacologic treatment is to reduce morbidity and mortality." | ( Calvo, G; Delgadillo, J; Horas, M; Ríos, J; Roca-Cusachs, A; Terán, M; Torres, F, 2001) |
| "Gene therapy for hypertension is needed for the next generation of antihypertensive drugs." | ( Phillips, MI, 2001) |
| "Isolated systolic hypertension is the most common type of hypertension in the elderly." | ( Berardelli, M; Ciotti, D; Gareri, P; Mattace, R; Olivo, M; Ritacco, AR; Rotundo, A, 2001) |
| "Thus, hypertension is associated with impaired NO-mediated vasodilation in the conduit brachial artery." | ( Biegelsen, E; Cupples, LA; Demissie, S; Duffy, SJ; Gokce, N; Holbrook, M; Keaney, JF; Loscalzo, J; Vita, JA, 2001) |
| "Hypertension is the most common cardiovascular risk factor in the U." | ( Davis, MM; Jones, DW, 2002) |
| "Resistant arterial hypertension is uncommon when there is good compliance to antihypertensive therapy and secondary causes have been ruled out." | ( Downey, P; Fajuri, A; Valdés, G, 2001) |
| "Family history of hypertension is an important determinant of hypertension." | ( Bhagwat, N; Hakim, A; Kamath, S; Kulkarni, V; Soneji, SL, 2001) |
| "Essential hypertension is among the most common and most costly medical conditions in the United States." | ( Brenner, R; Henrie-Olson, J; Patterson, AJ, 2002) |
| "Hypertension is associated with greater than normal lipoperoxidation and an imbalance in antioxidant status, suggesting that oxidative stress is important in the pathogenesis of this disease." | ( Ruiz-Gutiérrez, V; Santa-Maria, C; Vázquez, CM, 2001) |
| "Isolated systolic hypertension is associated with elevated cardiovascular morbidity and mortality and is primarily due to large artery stiffening, which has been independently related to cardiovascular mortality." | ( Baguet, JP; Cameron, JD; Dart, AM; Ferrier, KE; Jennings, GL; Kingwell, BA; Muhlmann, MH, 2002) |
| "Hypertension is a risk factor for coronary heart disease." | ( Ikeda, U; Lee, RT; Mano, H; Ohki, R; Shimada, K; Yamamoto, K, 2002) |
| "Obesity and hypertension are closely associated risk factors for cardiovascular disease." | ( Sharma, AM, 2001) |
| "The risk of hypertension is poorly documented in this setting." | ( Boralevi, F; Labbé, L; Léauté-Labrèze, C; Marlière, V; Roul, S; Taïeb, A; Thédenat, B, 2002) |
| "Hypertension is one of the main components of this syndrome." | ( Kazdová, L; Lánská, V; Pelikánová, T; Vlasáková, Z, 2002) |
| "Hypertension is associated with an increase in coronary artery disease, but little is known about the regulation of coronary vascular tone by endothelin-1 (ET-1) in hypertension." | ( Fuchs, LC; Giulumian, AD; Molero, MM; Pollock, DM; Pollock, JS; Reddy, VB, 2002) |
| "Essential hypertension is a prevalent complex polygenic disease and a major risk factor for cardiovascular disease, the leading cause of death in developed countries." | ( Herrera, VL; Lopez, LV; Ruiz-Opazo, N, 2002) |
| "Both obesity and hypertension are associated with endothelial dysfunction." | ( Chayama, K; Goto, C; Hara, K; Higashi, Y; Kimura, M; Matsuura, H; Nakagawa, K; Noma, K; Oshima, T; Sasaki, S, 2002) |
| "Hypertension is resistant to pharmacologic therapy in 5% to 10% of patients." | ( Carré, E; Lincoff, AM; Mertes, M; Ouzan, J; Pérault, C, 2002) |
| "Hypertension is a major public health problem both in the developing and developed countries of the world and if untreated, can lead to various fatal complications like cerebral stroke, encephalopathy, ischaemic heart disease (IHD), renal failure and sudden cardiac death, etc." | ( Arora, P; Neki, NS, 2001) |
| "Hypertension is a major risk factor for cardiovascular morbidity and mortality." | ( Oparil, S, 2002) |
| "Hypertension is associated with impaired fibrinolysis." | ( Appel, LJ; Bohannon, AD; Conlin, PR; Erlinger, TP; Macko, RF; Miller, ER; Moore, TJ; Svetkey, LP, 2002) |
| "Hypertension is closely associated with vascular endothelial dysfunction." | ( Arican, N; Cimen, V; Elmas, I; Kalayci, R; Kaya, M; Korkut, F; Kucuk, M; Kudat, H, 2002) |
| "Hypertension is common in type 2 diabetes with diabetic nephropathy, and increases the risk of cardiovascular complications and renal chronic insufficiency." | ( Aguilar, E; Beguer, P; Boned, B; Gimeno, JA; Gómez Sánchez, R; Labrador, T; Lou, LM; Lou, MT, 2002) |
| "The development of hypertension is accompanied by changes in the rheological properties of blood, particularly by increased red blood cell (RBC) aggregation leading to further pathological complications." | ( Dean, WL; Joshua, IG; Lominadze, D; Schuschke, DA, 2002) |
| "Hypertension is a widespread phenomenon whose ultimate cause is still unknown." | ( Aloisi, C; Buemi, M; Corica, F; Frisina, N; Romeo, A; Senatore, M; Tramontana, D, 2002) |
| "Hypertension is more prevalent in the African American population when compared with the European American population in the United States." | ( Andrew, ME; Brown, CA; Jones, DW; Schreiner, PJ; Taylor, HA; Wofford, MR; Wyatt, SB; Young, DB, 2002) |
| "Hypertension is a complex trait with an ill-defined genetic predisposition, in which adrenergic mechanisms seem to be involved even at the early stages." | ( Kailasam, MT; Kennedy, BP; O'Connor, DT; Parmer, RJ; Yanaihara, N; Ziegler, MG, 2002) |
| "Hypertension is one of the main risk factors for stroke." | ( Bacellar, AS; Jesus, PA; Oliveira-Filho, J; Pedreira, BB; Souza, PE, 2002) |
| "Hypertension is considered to be a complex trait to which genetic, environmental, and demographic factors contribute interactively." | ( Kato, N, 2002) |
| "Essential hypertension is associated with alterations in endothelial function." | ( Kim, CH; Lee, MM; Oh, BH; On, YK; Park, YB, 2002) |
| "Hypertension is a rare side effect of carbamazepine." | ( Guberman, A; Jette, N; Veregin, T, 2002) |
| "Hypertension is a serious health problem in Western society, in particular for the African-American population." | ( Agarwal, Y; Brown, CD; Jain, S; Kumar, A; Narayanan, CS; Ott, J; Peterson, SM; Tang, X, 2002) |
| "Essential hypertension is one of the most important risk factors for cardiovascular diseases." | ( Adamek-Guzik, T; Korbut, RA, 2002) |
| "Essential hypertension is a common disorder, associated with increased endothelin-1-mediated vasoconstrictor tone at rest." | ( Jenkins, DG; McEniery, CM; Webb, DJ; Wilkinson, IB, 2002) |
| "Although systemic hypertension is very common in patients with glomerulonephritis there is a dispute if this alteration is consequence of the glomerulonephritis "per se" or is a consequence of the renal failure secondary to the glomerular lesion." | ( Corpa, MV; Soares, V, 2002) |
| "Aldosterone-induced hypertension is associated with renal damage that may be mediated by endothelin-1 (ET-1)." | ( Chen, X; He, G; Schiffrin, EL; Tostes, RC; Touyz, RM, 2002) |
| "Hypertension is a major risk factor in the development of cardiovascular disease." | ( Davenport, AP; Kuc, RE; Maguire, JJ; Ohlstein, E; Télémaque-Potts, S; Yanagisawa, M, 2002) |
| "After age, hypertension is the most powerful stroke risk factor." | ( Namazi, MR, 2002) |
| "Hypertension is the most common medical complication of pregnancy in South Africa and a major cause of maternal and perinatal morbidity and mortality worldwide." | ( Moodley, J, 1993) |
| "Hypertension is a risk factor for dementia and is associated with some of the brain changes that are found in Alzheimer's disease and other neurodegenerative diseases, such as atrophy and neurofibrillary tangles." | ( Benedetti, C; Catani, M; Cherubini, A; Howard, R; Mariani, E; Mecocci, P; Metastasio, A; Pelliccioli, GP; Senin, U; Tarducci, R, 2002) |
| "Chronic hypertension is associated with an increased risk for tissue injury that may be mediated in part by endothelium and inflammatory cells." | ( Delano, FA; Mun, KC; Schmid-Schönbein, GW; Tran, ED, 2002) |
| "Hypertension is twice as common in postmenopausal than in premenopausal women." | ( Abellán, J; de Castro, SS; De Vinuesa, SG; Fernández-Vega, F; Luño, J; Maceira, B; Nicolás, RR; Rodríguez, JC; Vegazo, O, 2002) |
| "Arterial hypertension is highly prevalent after renal transplantation and may contribute to the risk of cardiovascular disease." | ( Morales, JM, 2002) |
| "Hypertension is a leading cause of end-stage renal disease (ESRD) in the United States, with no known treatment to prevent progressive declines leading to ESRD." | ( Agodoa, LY; Appel, LJ; Bakris, G; Charleston, J; Cheek, D; Douglas-Baltimore, JG; Gassman, J; Glassock, R; Greene, T; Hebert, L; Jamerson, K; Lewis, J; Middleton, JP; Phillips, RA; Rostand, SG; Toto, RD; Wright, JT, 2002) |
| "Human hypertension is a complex, multifactorial disease with a heritability of more than 30-50%." | ( Bengra, C; Felder, RA; Jose, PA; Khripin, Y; Manunta, P; Mifflin, TE; Williams, SM, 2002) |
| "Hypertension is often associated with insulin resistance, dyslipidemia and obesity, which indicate a prediabetic state and increased risk of cardiovascular disease." | ( Badenhoop, K; Füllert, S; Haak, E; Konrad, T; Lübben, G; Rau, H; Schneider, F; Usadel, KH, 2002) |
| "Hypertension is associated with alterations in resistance artery endothelial function." | ( Chayama, K; Goto, C; Hara, K; Higashi, Y; Kimura, M; Nakagawa, K; Noma, K; Oshima, T; Sasaki, S; Yoshizumi, M, 2002) |
| "Type 2 diabetes and hypertension are both associated with an increased risk of atherothrombosis." | ( Barden, A; Beilin, LJ; Burke, V; Mori, TA; Puddey, IB; Watts, GF; Woodman, RJ, 2003) |
| "Hypertension is associated with a remodeling of arterial smooth muscle K(+) channels with Ca(2+)-gated K(+) channel (BK(Ca)) activity being enhanced and voltage-gated K(+) channel (K(v)) activity depressed." | ( Cox, RH; Dietz, NJ; Lozinskaya, I, 2003) |
| "Arterial hypertension is associated with an increased vascular tone of resistance vessels, a reduced compliance of conduit arteries, along with a thickening of the intima-media leading to vascular remodeling." | ( Kelm, M, 2003) |
| "Hypertension is a leading cause of cardiovascular, cerebral, and renal disease morbidity and mortality, and epidemiological evidence suggests a role for sex-dependent mechanisms in the pathophysiology of hypertension." | ( Capdevila, JH; Marji, JS; Nakagawa, K; Schwartzman, ML; Waterman, MR, 2003) |
| "Two-week DOCA-salt hypertension is associated with enhanced coronary vasoconstrictor effects of endothelin, vasopressin and angiotensin II." | ( de Champlain, J; Lamontagne, D; Millette, E, 2003) |
| "Hypertension is a disease caused by multiple genes." | ( Wang, ZG; Wen, SJ; Wu, ZS, 2001) |
| "Renovascular hypertension is accompanied by increased renin-angiotensin system activity." | ( Alba, F; Banegas, I; de Gasparo, M; Hermoso, F; Prieto, I; Ramírez, M; Segarra, AB; Vargas, F, 2003) |
| "Hypertension is a risk factor for dementia, particularly vascular dementia." | ( Seux, ML, 1999) |
| "Isolated systolic hypertension is the predominant form of hypertension in the elderly population." | ( Dao, HH; Essalihi, R; Moreau, P; Yamaguchi, N, 2003) |
| "Hypertension is a potentially dangerous side effect of erythropoietin treatment; however, extreme elevations in blood pressure are rare." | ( Force, RW; Mumford, BT; Novak, BL; Solbrig, RM, 2003) |
| "Since hypertension is considered as a risk factor for renal disease progression, insulin resistance may be an indirect deteriorating factor for IgAN." | ( Asahi, K; Eiro, M; Katoh, T; Sakuma, Y; Sakurai, K; Suzuki, H; Watanabe, K; Watanabe, T, 2003) |
| "Arterial hypertension is now diagnosed in 67-90% of patients after renal transplantation." | ( Paczek, L; Pilecki, T; Rowiński, W; Senatorski, G; Szmidt, J; Wyzgał, J; Zegarska, J, 2002) |
| "Systolic hypertension is the most common form of hypertension, particularly in people aged >60 years." | ( Connelly, JE; Estok, RP; Fahrbach, KR; Frame, D; Levine, CB; Ludensky, V; Stone, LR, 2003) |
| "Hypertension is one of the most powerful and prevalent contributor of ahterosclerotic cardiovascular disease." | ( Masszi, G, 2002) |
| "Hypertension is associated with a number of adverse morphologic and functional changes in the cardiovascular system, including left ventricular (LV) hypertrophy." | ( Hallberg, P; Kahan, T; Karlsson, J; Kurland, L; Lind, L; Malmqvist, K; Melhus, H; Michaëlsson, K; Nyström, F; Ohman, KP, 2003) |
| "Essential hypertension is associated with impaired endothelium-dependent vasodilation caused by oxidative stress-induced nitric oxide (NO) breakdown and compensatory production of a hyperpolarizing factor." | ( Ghiadoni, L; Magagna, A; Salvetti, A; Salvetti, G; Taddei, S; Versari, D; Virdis, A, 2003) |
| "Hypertension is a common finding among diabetic patients and increases their morbidity and mortality." | ( Kalantarinia, K; Siragy, HM, 2002) |
| "Hypertension is a complex trait with an ill-defined genetic predisposition, in which renal mechanisms seem to be involved even at the early stages." | ( Kailasam, MT; Martinez, JA; O'Connor, DT; Parmer, RJ; Wong, CM, 2003) |
| "Hypertension is a major public health problem in developing countries." | ( Deepa, R; Mohan, V; Pradeepa, R; Premalatha, G; Saroja, R; Shanthirani, CS, 2003) |
| "These forms of hypertension are rather rare in their complete expression, but they point to candidate genes whose mutations may predispose to hypertension." | ( Bähr, V; Diederich, S; Oelkers, W, 2003) |
| "Rationale." | ( Broersen, LM; De Bruin, NM; De Wilde, MC; Kiliaan, AJ, 2003) |
| "Hypertension is associated with endothelial dysfunction and is characterized by a lack of response to endothelial-dependent vasoactive substances, including nitric oxide synthase inhibitors." | ( Kim, D; Li, L; Li, W; Prasad, P; Storey, P, 2003) |
| "Dyslipidemia and hypertension are frequently observed in patients with ischemic heart disease." | ( Mehta, JL; Singh, BM, 2003) |
| "Hypertension is one of the most important causes of cardiovascular disease, and treatment of hypertension leads to a significant reduction in cardiovascular mortality and morbidity." | ( Caglar, N; Canberk, A; Deger, N; Demirtas, M; Dortlemez, H; Kes, S; Kiliccioglu, B; Kozan, O; Ovunc, K; Turkoglu, C, 2003) |
| "Although hypertension is a risk factor for the development of end-stage renal disease, not all hypertensive patients progress to develop renal dysfunction." | ( Dial, R; Forde, P; Loscalzo, J; Scribner, AW; Trolliet, MR, 2003) |
| "This hypertension is abolished by selective angiotensin II receptor AT-1 antagonist at a low dose that does not affect BP in non-Tg littermates." | ( Elmquist, JK; Fleming, S; Flier, JS; Kenyon, CJ; Masuzaki, H; Morton, NM; Mullins, JJ; Paterson, JM; Seckl, JR; Sharp, MG; Shinyama, H; Yamamoto, H, 2003) |
| "Chronic hypertension is associated with resistance artery remodelling and mechanical alterations." | ( Arribas, SM; Briones, AM; Daly, CJ; Giraldo, J; González, JM; González, MC; McGrath, JC; Somoza, B; Vila, E, 2003) |
| "Mineralocorticoid hypertension is the consequence of an overactivity of the epithelial sodium channel expressed at the apical membrane of renal cells in the distal nephron." | ( Bonny, O; Ferrari, P, 2003) |
| "Hypertension is common in older adults (aged > or =65 years)." | ( DiCesare, J; Doan, QD; Floyd, K; Sacco, P; Sapienza, S, 2003) |
| "Hypertension is associated with endothelial dysfunction that is attributable to oxidative stress and a proinflammatory state." | ( Duffy, SJ; Eberhardt, RT; Gokce, N; Holbrook, M; Keaney, JF; Maxwell, C; Morrow, JD; Palmisano, J; Price, DT; Vita, JA; Widlansky, ME, 2003) |
| "Hypertension is an age-dependent disorder." | ( Guo, Z; Polley-Mandal, M; Shi, M; Uddin, M; Yang, H, 2003) |
| "Essential hypertension is a common disease caused by a combination of genetic and environmental factors." | ( Anania, V; Palomba, D; Satta, M; Varoni, MV, 2003) |
| "Hypertension is a major risk factor for cardiovascular diseases such as stroke, myocardial infarction, and heart failure, the leading causes of death in the Western world." | ( Baum, HP; Bedigian, MP; Cohen, NC; Cumin, F; Fuhrer, W; Göschke, R; Grütter, MG; Herold, P; Jensen, C; Mah, R; Maibaum, J; O'Brien, E; Rahuel, J; Rasetti, V; Rigollier, P; Rüger, H; Schilling, W; Schnell, CR; Stanton, A; Stutz, S; Wood, JM; Yamaguchi, Y, 2003) |
| "Essential hypertension is a very heterogeneous disease and different pressor mechanisms might interact to increase blood pressure." | ( Waeber, B, 2003) |
| "Hypertension is a major health problem in both developed and developing countries." | ( Belleville, JL; Bouchenak, M; Cherrad, A; Krouf, D; Mohammedi, B; Prost, JL, 2003) |
| "Hypertension is a clinical syndrome characterized by increased vascular tone." | ( Amberg, GC; Bonev, AD; Nelson, MT; Rossow, CF; Santana, LF, 2003) |
| "Hypertension is a significant risk factor for vascular complications of diabetes, and the target blood pressure in patients with diabetes or chronic renal disease and hypertension should be lower than that in patients with hypertension alone." | ( Gay, C; Gunning, K; Magill, MK; Saffel-Shrier, S, 2003) |
| "Arterial hypertension is closely correlated with the occurrence of stroke and also with the loss of cognitive function and dementia." | ( Leys, D, 2003) |
| "Essential hypertension is associated with impairment of both endothelial function and insulin action, and this has provided rationale for the use of antihypertensive agents that are at least neutral, if not beneficial, in these areas." | ( Atkinson, AB; Bassett, J; Bell, PM; Courtney, CH; Ennis, CN; McCance, DR; Sheridan, B, 2003) |
| "Although hypertension is a major risk factor for atherosclerosis, its underlying mechanisms remain to be delineated." | ( Chen, AF; Chu, Y; Engelhardt, JF; Fink, GD; Heistad, DD; Li, L, 2003) |
| "Hypertension is a risk factor for PAD." | ( Lip, GY; Makin, AJ, 2003) |
| "The origin of hypertension is detailed based upon the findings of kidney functional parameters and endothelium function studies." | ( Carvalho, MH; Coimbra, TM; do Carmo Pinho Franco, M; Fortes, ZB; Gil, FZ; Gomes, GN; Lucas, SR; Nigro, D; Tostes, RC, 2003) |
| "Hypertension is an important risk factor for coronary atherosclerosis, which is accelerated by inflammation and diminished fibrinolysis." | ( Dong, J; Fujii, S; Furumoto, T; Goto, D; Imagawa, S; Kaneko, T; Kitabatake, A; Mishima, T; Nakai, Y; Zaman, TA, 2003) |
| "Non-adherence in hypertension is a global problem and promoting adherence is necessary to decrease cardiovascular mortality." | ( Hamilton, GA, 2003) |
| "Arterial hypertension is one of the most important factors leading to chronic graft nephropathy and causing cardiovascular complications following renal transplantation." | ( Glyda, M; Kościanska, L; Kołodziejczyk, J; Manitius, J; Sulikowska, B; Włodarczyk, Z, 2003) |
| "Arterial hypertension is a risk factor for atherosclerosis of whose pathogenesis is unknown." | ( Candelli, M; Franceschi, F; Gasbarrini, G; Mettimano, M; Migneco, A; Montebelli, R; Ojetti, V; Savi, L; Specchia, L, 2003) |
| "Hypertension is accompanied by circulatory changes in the brain and in other vascular districts; at disease onset, these changes may be largely functional and dependent on metabolic and vegetative drives." | ( Bojic, T; Cianci, T; Franzini, C; Lenzi, P; Lucchi, ML; Silvani, A; Zoccoli, G, 2004) |
| "1." | ( Schiffrin, EL; Tabet, F; Touyz, RM, 2003) |
| "Hypertension is an important determinant of heart failure." | ( Weber, KT, 2003) |
| "Hypertension is the most important risk factor for stroke and vascular dementia." | ( Diener, HC; Lüders, S; Schrader, J, 2003) |
| "Hypertension is directly responsible for 57% of all stroke deaths and 24% of all coronary heart disease deaths in India." | ( Gupta, R, 2004) |
| "Obesity and hypertension are increasing medical problems in adolescents." | ( Dieuzeide, G; García, SI; González, C; Landa, MS; Pirola, CJ; Porto, PI, 2004) |
| "Hypertension is a common problem in individuals with diabetes mellitus." | ( Haq, IU; Khsandwala, H; Prasad, K; Qureshi, M, 2003) |
| "Hypertension is a major disease of later life affecting 25% of the adult population in the industrialized world with most hypertensive individuals diagnosed as having essential hypertension." | ( Odermatt, A, 2004) |
| "Essential hypertension is a multifactorial disease in which genetic and enviromental factors play an important role." | ( Agachan, B; Akoglu, E; Isbir, T; Yilmaz, H, 2003) |
| "The prevalence of hypertension is greater in African Americans, and management of this condition presents challenges for practicing physicians." | ( Batchelor, A; Cohn, JN; Dong, V; Guo, W; Julius, S; Lagast, H; Neutel, J; Shen, Y; Turlapaty, P; Weber, M, 2004) |
| "Hypertension is a major risk factor for cardiovascular events and the goal of treating hypertension is to prevent complications due to these events." | ( Fujimoto, H; Kawashima, T; Koide, S; Kunitake, T; Yamamoto, S, 2003) |
| "This sustained hypertension is not due to any anatomical fault in the kidney and in that sense is not primarily renal in origin." | ( FRIEDMAN, CL; FRIEDMAN, SM; NAKASHIMA, M, 1951) |
| "Arterial hypertension is one of the major risk factors in cardiovascular and renal disease." | ( Savoia, C; Schiffrin, EL, 2004) |
| "Resistant hypertension is an important public health problem, its prevalence varies between 30 to 50 per cent." | ( Archawarak, N; Sermswan, A, 2003) |
| "1." | ( Bogdański, P; Kujawska-Łuczak, M; Pupek-Musialik, D; Łacki, J, 2003) |
| "Hypertension is characterized by abnormal vascular contractility and function." | ( Loberg, RD; Northcott, CA; Watts, SW; Wehrwein, EA, 2004) |
| "Salt-sensitive hypertension is associated with impaired NO/cGMP signaling." | ( Elmarakby, AA; Kemp, BE; Pollock, DM; Pollock, JS; Sasser, JM; Sullivan, JC, 2004) |
| "Many forms of hypertension are associated with increased oxidative stress." | ( Croft, KD; McKenzie, KU; Mori, TA; Schyvens, CG; Whitworth, JA; Zhang, Y, 2004) |
| "Hypertension is common after liver transplantation." | ( Alexander, GJ; Brown, MJ; Byrne, CD; Neal, DA; Wilkinson, IB, 2004) |
| "Hypertension is a major risk factor for cardiovascular morbidity and mortality." | ( Chrysant, SG, 2003) |
| "Hypertension is frequently associated with the development of renal vascular and glomerular fibrosis." | ( Chansel, D; Chatziantoniou, C; Dussaule, JC; Flamant, M; François, H; Placier, S; Tharaux, PL, 2004) |
| "Hypertension is associated with impaired endothelial function, which can be explained by a decrease in nitric oxide (NO) generation or by an enhanced inactivation of NO after its release from endothelial cells." | ( Bogdanska, J; Jovanoska, E; Korneti, P; Kostova, E; Petrov, S; Slaninka-Miceska, M, 2003) |
| "Hypertension is associated with alteration in endothelial function mediated through reduced nitric oxide (NO) bioavailability." | ( Higashi, Y; Yoshizumi, M, 2004) |
| "Hypertension is a major risk factor for morbidity and mortality." | ( Fossum, E; Høieggen, A; Ibsen, H; Julius, S; Kjeldsen, SE; Olsen, MH; Reims, HM; Wachtell, K, 2004) |
| "Hypertension is the most prevalent risk factor for cardiovascular diseases, present in almost 30% of adults." | ( Fernández-Fernández, JM; Latorre, R; Marrugat, J; Orio, P; Sentí, M; Tomás, M; Valverde, MA; Vázquez, E, 2004) |
| "Severe hypertension is commonly treated with parenteral hydralazine, labetalol, or magnesium sulphate." | ( Caetano, M; Gruslin, A; Hannah, ME; Logan, AG; Magee, LA; Ornstein, MP; Von Dadelszen, P; Willan, A, 2004) |
| "Hypertension is becoming a major public health problem in developing countries." | ( Babu, BV; Kusuma, YS; Naidu, JM, 2004) |
| "While hypertension is a complex disease with a well-documented genetic component, genetic studies often fail to replicate findings." | ( Addy, JH; Dawson, E; Dzhura, E; Felder, RA; Jose, PA; Kpodonu, J; Moore, JH; Phillips, JA; Prince, M; Ritchie, MD; Semenya, A; Summar, M; White, BC; Williams, SM; Willis, A; Wong, LJ, 2004) |
| "If a patient's hypertension is severe enough to warrant minoxidil therapy, a hypertension specialist should probably become involved in the patient's care." | ( Sica, DA, 2004) |
| "Hypertension is commonly associated with Wilms tumor, but hypertension secondary to renin-secreting Wilms tumor is uncommon." | ( Mauger, D; Wong, W, 2004) |
| "Hypertension is a common condition associated with increased mortality and multiple morbidities." | ( Anjum, S; Littler, WA; Shah, SU, 2004) |
| "Hypertension is one of the most important modifiable risk factors for cardiovascular pathology, such as atherosclerosis and cardiac left ventricular hypertrophy, including acute events such as stroke and myocardial infarction (MI)." | ( Unger, T; Zimmermann, M, 2004) |
| "Hypertension is often poorly controlled, despite its importance and despite the availability of very effective treatments." | ( Burnier, M; Ferrari, P; Hess, L; Muggli, F; Pechere-Bertschi, A, 2004) |
| "Arterial hypertension is a major risk factor for cardiovascular events." | ( Akman, D; Ali, I; Brendorp, B; Bruun, NE; Køber, L; Møller, J; Ottesen, M; Torp-Pedersen, C, 2004) |
| "In conclusion, hypertension is a common disease in this area and is associated with multiple risk factors for cardiovascular disease." | ( Mafauzy, M; Mokhtar, N; Wan Mohamad, WB, 2003) |
| "Hypertension is often viewed solely as a disease of the adult." | ( Jones, JE; Jose, PA, 2004) |
| "Essential hypertension is associated with enhanced LDL oxidation and impaired endothelium-dependent vasodilation." | ( Condorelli, M; de Nigris, F; Ignarro, LJ; Liguori, A; Napoli, C; Pignalosa, O; Sica, V, 2004) |
| "Hypertension is a common trait worldwide and is responsible for a major expenditure of health-care dollars in the United States." | ( Mindel, G; Morrison, AR, 2004) |
| "Hypertension is a common and difficult clinic problem in patients undergoing cronical hemodialysis and exerts a deleterious effect on mordibidy and mortality in end stage renal disease." | ( Ceballos, M; García Cortés, MJ, 2004) |
| "Hypertension is one of the most important risk factors for stroke, and treatment with a variety of antihypertensive agents reduces the risk." | ( Mancia, G, 2004) |
| "Hypertension is underdiagnosed and undertreated, and recommended target blood pressures are rarely achieved." | ( McInnes, GT, 2004) |
| "Hypertension is a well-established risk factor for myocardial infarction (MI), but its prognostic importance in survivors of an acute MI is less clear." | ( Bernstein, V; Braunwald, E; Brown, EJ; Dagenais, GR; Davis, BR; Gordon, D; Kenchaiah, S; Lamas, GA; Pfeffer, MA; Rouleau, JL; Steingart, RM; Sussex, B, 2004) |
| "Hypertension is associated with reduced coronary vasodilatory capacity, possibly caused by structural changes in the coronary resistance vessels." | ( Buus, NH; Bøttcher, M; Christensen, KL; Jørgensen, CG; Mulvany, MJ; Nielsen, TT; Thygesen, K, 2004) |
| "Isolated systolic hypertension is the predominant form of hypertension in the elderly, and stroke is the most common cardiovascular (CV) complication." | ( Elmfeldt, D; Farsang, C; Hofman, A; Lithell, H; Olofsson, B; Papademetriou, V; Skoog, I; Trenkwalder, P; Zanchetti, A, 2004) |
| "Essential hypertension is often accompanied by abnormalities of the coagulation/fibrinolytic system predisposing to a procoagulant state." | ( Hatzizacharias, A; Krespi, P; Makris, TK; Papadopoulos, DP; Stavroulakis, G; Tsoukala, C; Votteas, VE; Zilidis, A, 2004) |
| "Hypertension is one of the most important risk factors for coronary heart disease." | ( Cañizares, J; Catalá, A; Montero, E; Perona, JS; Ruiz-Gutiérrez, V; Sánchez-Domínguez, JM, 2004) |
| "Hypertension is the most common." | ( Simons, S; Sloan, B; Stromwall, A, 2004) |
| "Obesity and hypertension are 2 closely associated conditions and obesity probably predisposed to hypertension." | ( Al-Hazimi, AM; Syiamic, AY, 2004) |
| "Hypertension is associated with changes in concentrations of vasoactive peptides and procollagen propeptides, but their relationships with left ventricular hypertrophy and cardiac function are unclear." | ( Linnaluoto, M; Peuhkurinen, K; Risteli, J; Ruskoaho, H; Tokola, H; Uusimaa, P; Vuolteenaho, O; Ylitalo, A, 2004) |
| "Hypertension is a major healthcare problem afflicting nearly 50 million individuals in the United States." | ( Gokce, N, 2004) |
| "Arterial hypertension is one of the major cardiovascular risk factors in Western countries." | ( Naber, CK; Siffert, W, 2004) |
| "Hypertension is a major risk factor for progressive renal failure." | ( Ellis, D; Janosky, JE; Moritz, ML; Vats, A, 2004) |
| "Hypertension is a major cardiovascular risk factor, but most patients remain asymptomatic for many years." | ( Papademetriou, V; Ross, A, 2004) |
| "Osteoarthritis and hypertension are highly prevalent among older Americans." | ( Coupal, L; Grover, SA; Zowall, H, 2005) |
| "Women with chronic hypertension are at increased risk for superimposed preeclampsia." | ( August, P; Cook, EF; Helseth, G; Sison, C, 2004) |
| "Hypertension is a relatively common manifestation of AD." | ( Assadi, F; Czech, K; Palmisano, JL, 2004) |
| "Essential hypertension is a major cause of cardiovascular morbidity and mortality in the Western world, yet it remains poorly controlled." | ( Ferro, A; Welsh, L, 2004) |
| "Hypertension is considered resistant if blood pressure cannot be reduced to <140/90 mmHg with an appropriate triple-drug regimen, including an oral diuretic, with all agents administered at maximal dosages." | ( Berezovsky, A; Laszt, A; London, D; Magen, E; Mishal, J; Priluk, R; Viskoper, R; Yosefy, C, 2004) |
| "Hypertension is a serious health problem particularly for African-Americans." | ( Jain, S; Kumar, A; Li, Y; Patil, S, 2005) |
| "Essential hypertension is a common, polygenic, complex disorder resulting from interaction of several genes with each other and with environmental factors such as obesity, dietary salt intake, and alcohol consumption." | ( Liu, P; Loh, M; Mondry, A; Nagel, M; Zhu, AL, 2005) |
| "Untreated hypertension is associated with disturbed glutathione redox status and increased plasma homocysteine concentrations." | ( Fischer, K; Kairane, C; Kampus, P; Muda, P; Ristimäe, T; Teesalu, R; Zilmer, K; Zilmer, M, 2005) |
| "Because hypertension is associated with potentially reversible structural and functional alterations in the cerebral circulation that may improve with treatment, we investigated whether long-term pharmacological reduction of systolic blood pressure will improve, rather than worsen, cerebral blood flow and its regulation." | ( Babikian, V; Cheng, DM; Cupples, LA; Gagnon, M; Iloputaife, I; Kiely, DK; Lipsitz, LA; Serrador, J; Sorond, F; Vyas, M, 2005) |
| "Essential hypertension is frequently associated with insulin resistance of skeletal muscle glucose transport, with a potential role of angiotensin II in the pathogenesis of both conditions." | ( Diehl, CJ; Dokken, BB; Henriksen, EJ; Kim, JS; Lailerd, N; Lemieux, AM; Saengsirisuwan, V; Sloniger, JA, 2005) |
| "Poorly controlled hypertension is a major risk for cardiovascular morbidity and mortality, strokes, heart failure and renal failure." | ( Chrysant, GS; Chrysant, SG; Desai, A, 2005) |
| "Hypertension is epidemic and currently affects 25% of the world's population and is a major cause of stroke, congestive heart failure, and end-stage renal disease." | ( Cade, JR; Johnson, RJ; Oliver, WJ; Rideout, BA; Titte, S, 2005) |
| "Hypertension is the most common form of cardiovascular disease." | ( Feig, DI, 2005) |
| "The dogma that hypertension is primarily a consequence of hemodynamic alterations has changed over the recent past, with compelling evidence that high blood pressure is linked to vascular damage, oxidative stress and inflammation." | ( Touyz, RM, 2005) |
| "Human essential hypertension is a classic example of a complex, multifactorial, polygenic disease with a substantial genetic influence in which the underlying genetic components remain unknown." | ( Brosnan, MJ; Dominiczak, AF; Graham, D; Hamilton, CA; Hanlon, N; Lee, WK; Mathers, J; McBride, MW; McLellan, LI; Miller, WH; Polke, JM, 2005) |
| "Hypertension is related to sodium intake, and many patients with essential hypertension are overweight and have the metabolic syndrome." | ( Cheung, BM; Lau, CP; Leung, RY; Man, YB; Wong, LY, 2005) |
| "Hypertension is an important modifiable risk factor for cardiovascular disease; its prevention and treatment currently represent major health concerns around the world, especially in western countries." | ( Leoncini, G; Parodi, A; Pontremoli, R, 2005) |
| "Hypertension is common following renal transplantation and adversely affects graft and patient survival." | ( Geddes, CC; Jardine, AG; Mark, PB; Rodger, RS; Stewart, GA; Tan, CC; Tutone, VK, 2005) |
| "Hypertension is a risk factor, which remains despite the use of anti-hypertensives, for reduced patient and graft survival." | ( Geddes, CC; Jardine, AG; Mark, PB; Rodger, RS; Stewart, GA; Tan, CC; Tutone, VK, 2005) |
| "Patients with hypertension are at high risk for the development of left ventricular dysfunction (LVD)." | ( Bhalla, MA; Bhalla, V; Clopton, P; Gardetto, N; Isakson, S; Lin, JP; Maisel, AS, 2005) |
| "Hypertension is associated with cognitive impairment in older adults." | ( Starr, JM; Whalley, LJ, 2005) |
| "Hypertension is a complex genetic disorder caused by interplay between several "risk" genes and environmental factors (genetic heritability approximately 30%)." | ( Agarwal, A; Fisher, ND; Williams, GH, 2005) |
| "Essential hypertension is a major public health concern worldwide where its prevalence accounts for various cerebrovascular diseases." | ( Duraisamy, G; Isaac, S; Ling, KH; Rosli, R; Say, YH, 2005) |
| "Diabetes and hypertension are potent risk factors for cerebrovascular disease." | ( Eguchi, K; Hoshide, S; Ishikawa, J; Ishikawa, S; Kario, K; Matsui, Y; Morinari, M; Shimada, K, 2005) |
| "Hypertension is the most common cardiovascular complication after liver transplantation." | ( Alexander, GJ; Brown, MJ; Neal, DA; Wilkinson, IB, 2005) |
| "Hypertension is associated with functional and morphological alterations of the endothelium, which disturbs delicate balance of endothelium-derived factors resulting in endothelial dysfunction." | ( Maru, VG; Sainani, GS, 2004) |
| "Hypertension is a major independent risk factor for cardiovascular disease." | ( Huntgeburth, M; Rosenkranz, S; Ten Freyhaus, H, 2005) |
| "Hypertension is the most common risk factor for hemorrhagic stroke." | ( Baumbach, GL; Faraci, FM; Heistad, DD; Iida, S; Lavoie, JL; Sigmund, CD, 2005) |
| "Hypertension is associated with increased cardio- and cerebrovascular morbidity and mortality; antihypertensive drugs have been shown to reduce the risk of adverse cardio- and cerebrovascular events." | ( Claas, SA; Glasser, SP, 2005) |
| "Diabetes and hypertension are also independent risk factors for VTE." | ( Bae, KT; Du, D; Hong, C; Pilgram, TK; Sicard, GA; Zhu, F, 2005) |
| "Hypertension is one of the results of the endocrinological deviation." | ( Hashizume, K, 2005) |
| "Hypertension is the most significant risk factor for stroke." | ( Bokura, H; Kobayashi, S, 2005) |
| "Hypertension is a major risk factor for developing coronary disease." | ( Bolad, I; Delafontaine, P, 2005) |
| "Hypertension is a modifiable risk factor for cardiovascular disease, but its aetiology has not been fully elucidated." | ( Fakhrzadeh, H; Ghotbi, S; Heshmat, R; Larijani, B; Nouri, M; Pourebrahim, R; Shafaee, A, 2005) |
| "Hypertension is an important modifiable cardiac risk factor in human immunodeficiency virus (HIV)-infected patients." | ( Aberg, JA; Fichtenbaum, CJ; Gerber, JG; Glesby, MJ; Grosskopf, N; Hafner, R; Hall, S; Kendall, MA; Zolopa, AR, 2005) |
| "Hypertension is a major cardiovascular risk factor, and its increasing prevalence is of great clinical concern." | ( Heagerty, AM, 2005) |
| "Hypertension is a multi-factorial process, prevalent in developed as well as in developing countries." | ( Jain, S; Kashyap, MK; Khullar, M; Kumari, S; Nath, R; Sharma, PC; Sherawat, BS; Yadav, V, 2005) |
| "Although hypertension is an important coronary risk factor, the influence to the EPCs is not fully understood." | ( Hano, T; Imanishi, T; Moriwaki, C; Nishio, I, 2005) |
| "Arterial hypertension is one of the reasons of high rate of mother and fetal mortality." | ( Estemberg, D; Estemberg, P; Karowicz-Bilińska, A; Kowalska-Koprek, U; Kuś, E, 2005) |
| "This hypertension is usually accompanied by bradycardia, particularly if the injury is caudal to the 2nd to 4th thoracic spinal segments." | ( Rabchevsky, AG, 2006) |
| "Essential hypertension is a heterogeneous disorder that is thought to develop because of several overlapping subsets of underlying mechanisms." | ( Bernard, M; Bouchard, G; Cowley, AW; Gaudet, D; Gossard, F; Hamet, P; Hudson, TJ; Jomphe, M; Kaldunski, ML; Kotchen, TA; Pausova, Z; Tremblay, J, 2005) |
| "Pulmonary hypertension is common in patients with chronic obstructive pulmonary disease (COPD), but the precise mechanism of vascular impairment in these patients is unknown." | ( Baraldo, S; Casoni, G; Cella, G; Papi, A; Rigno, M; Saetta, M; Turato, G, 2005) |
| "Hypertension is a multifactorial disorder that probably results from the inheritance of a number of susceptibility genes and involves multiple environmental determinants." | ( Marteau, JB; Siest, G; Visvikis-Siest, S; Zaiou, M, 2005) |
| "Systolic hypertension is predominant among patients over 50 years of age, is a more important cardiovascular risk factor than diastolic blood pressure, and is more difficult to control than diastolic blood pressure." | ( Gatlin, M; Neutel, JM; Purkayastha, D; Schofield, L; Smith, DH; Weber, MA, 2005) |
| "Because hypertension is a risk factor for left ventricular (LV) hypertrophy and because evidence from animal models suggests that AGT may play a role in the growth and hypertrophy of the heart, we chose to conduct a population association study examining the relationship of 10 SNPs in the AGT gene with 7 different LV phenotypes measured by echocardiography." | ( Arnett, DK; Chakravarti, A; Chang, YP; Devereux, RB; Gu, CC; Lewis, CE; Li, N; Miller, MB; North, KE; Rasmussen-Torvik, LJ; Wilk, JB, 2005) |
| "Hypertension is known to be associated with an oxidative stress resulting from an imbalance of antioxidant defense mechanisms in various tissues." | ( Berthelot, A; Bouhaddi, M; Courderot-Masuyer, C; Elhaïmeur, F; Guyon, C; Nicod, L; Regnard, J; Richert, L; Robin, S, 2005) |
| "Hypertension is the most common chronic disease and is the leading risk factor for death caused by stroke, myocardial infarction, and end-stage renal failure." | ( Iwamoto, T; Katsuragi, T; Kita, S, 2005) |
| "Hypertension is an independent risk factor for the development of contrast nephropathy." | ( Buerkle, G; Buettner, HJ; Conen, D; Mueller, C; Perruchoud, AP, 2006) |
| "Essential hypertension is frequently associated with insulin resistance of skeletal muscle glucose transport, and angiotensin II (ANGII) can contribute to the pathogenesis of both conditions." | ( Diehl, CJ; Henriksen, EJ; Kim, JS; Saengsirisuwan, V; Sloniger, JA, 2005) |
| "Hypertension is more prevalent in women than in men with ACS, and its medical management varies by sex, but its association with mortality is similar." | ( Armstrong, PW; Aylward, PE; Bhapkar, MV; Frazier, CG; Klein, WW; Kristinsson, A; McGuire, DK; Newby, LK; Sadowski, Z; Shah, SH; Weaver, WD, 2005) |
| "Systemic hypertension is associated with increased risk for coronary artery disease, stroke, nephrosclerosis, peripheral vascular disease, etc." | ( Chopra, D; Joshi, RM; Joshi, SR; Kale, S; Oomman, A, 2005) |
| "Hypertension is a major underlying disease that may cause left ventricular (LV) diastolic dysfunction, even without LV systolic dysfunction, and antihypertensive drugs could affect LV diastolic function." | ( , 2006) |
| "Hypertension is common in chronic renal disease and is a risk factor for the faster progression of renal damage, and reduction of blood pressure (BP) is an efficient way of preventing or slowing the progression of this damage." | ( Wenzel, RR, 2005) |
| "Hypertension is the most common chronic disease, and is the leading risk factor for death caused by stroke, myocardial infarction, and end-stage renal failure." | ( Iwamoto, T, 2006) |
| "Hypertension is a major pathophysiological determinant of progressive arterial damage that can accelerate the development of diabetic nephropathy." | ( Pugsley, MK, 2005) |
| "Essential hypertension is a complex multifactorial disorder with epigenetic and environmental factors contributing to its prevalence." | ( Irmak, MK; Sizlan, A, 2006) |
| "As hypertension is a disease in which free radicals and large vessel elasticity are involved, this article will examine the possible mechanisms by which glycine may protect against high blood pressure." | ( Baños, G; El Hafidi, M; Pérez, I, 2006) |
| "Hypertension is the principal risk factor for cerebral infarctions and intracerebral hematoma." | ( Benatru, I; Caillier, M; Contegal, F; Durier, J; Fromont, A; Giroud, M; Menassa, M; Moreau, T; Osseby, GV; Rouaud, O; Vernet, B, 2006) |
| "Hypertension is a common problem in elderly patients, which usually requires chronic therapy under various physiological conditions including low gastric acidity (hypo- or anacidity)." | ( Ahn, BO; Choi, SM; Kim, JE; Kwon, JW, 2006) |
| "Primary hypertension is a modifiable risk factor for both cardiovascular disease and chronic kidney disease." | ( Rosario, RF; Wesson, DE, 2006) |
| "Hypertension is a predisposing factor for the development of stroke, peripheral arterial disease, heart failure and end-state renal disease." | ( Godfraind, T, 2006) |
| "Hypertension is a chronic age-related disorder, affecting nearly 20% of all adult Europeans." | ( Babeanu, S; Bianchi, G; Brand, E; Brand-Herrmann, SM; Casiglia, E; Cwynar, M; Filipovský, J; Grodzicki, T; Kawecka-Jaszcz, K; Kuznetsova, T; Nikitin, Y; Peleska, J; Staessen, JA; Stolarz, K; Struijker-Boudier, H; Thijs, L; Tikhonoff, V; Wojciechowska, W, 2006) |
| "Furthermore, hypertension is a public health issue of great relevance in Baleric Islands (Spain)." | ( García-Marco, MA; Gomez, G; Marco, J; Mulet, JM; Munar, MA; Soler, J; Viader, C; Zabay, JM, 2005) |
| "Hypertension is also one of the major atherosclerotic risk factors." | ( Bumrerraj, S; Choenrungroj, T; Kosakarn, J; Limpawattana, P; Naranunn, P; Pradit, P; Premgamone, A; Punyamee, S; Sawanyawisuth, K; Thongmee, A, 2005) |
| "Hypertension is a complex disease influenced by multiple genetic and environmental factors." | ( Cobb, MH; Raman, M, 2006) |
| "Systemic hypertension is one of the main risk factors for atherothrombosis." | ( Bitto, A; Bonaiuto, A; Campo, S; Castaldo, M; Cristadoro, S; Saitta, A; Saitta, C; Sardo, MA; Trimarchi, G, 2006) |
| "Prehypertension is considered a precursor of stage 1 hypertension and a predictor of excessive cardiovascular risk." | ( Black, HR; Egan, BM; Grimm, RH; Julius, S; Kaciroti, N; Messerli, FH; Michelson, EL; Nesbitt, SD; Oparil, S; Schork, MA; Weber, MA, 2006) |
| "Hypertension is a major risk factor for atherosclerotic cardiovascular disease." | ( Baba, T; Hashimoto, S; Katoh, T; Midorikawa, S; Sanada, H; Watanabe, T; Yatabe, J; Yatabe, MS, 2005) |
| "Resistant hypertension is common in clinical practice." | ( Calò, LA; Cattelan, F; Ciccariello, L; De Toni, R; Macchini, L; Mascagna, V; Pessina, AC; Realdi, A; Sartori, M; Semplicini, A, 2006) |
| "Hypertension is associated with increased levels of oxidative stress and medullary renal injury." | ( Abe, M; Cowley, AW; Kaldunski, M; Liang, M; O'Connor, P; Roman, RJ, 2006) |
| "Arterial hypertension is involved in the pathogenesis of end organ damage by influencing the ability of the vascular endothelium to produce nitric oxide (NO)." | ( Delles, C; Harazny, J; Michelson, G; Oehmer, S; Schmieder, RE; Wärntges, S, 2006) |
| "Essential hypertension is associated with changes in central catecholaminergic pathways which might also be reflected in the pituitary response to stress stimuli." | ( Cizmarova, E; Huckova, M; Koska, J; Kvetnansky, R; Penesova, A; Radikova, Z; Vigas, M, 2006) |
| "Essential hypertension is considered to be a typical complex disease with multifactorial etiology, which leads to inconsistent findings in genetic studies." | ( Chen, R; Chen, S; Ge, D; Gu, D; Huang, J; Li, B; Qiang, B; Su, S, 2006) |
| "Hypertension is the most prevalent risk factor for stroke, myocardial infarction, or end-stage renal failure." | ( Iwamoto, T; Kita, S, 2006) |
| "Hypertension is a major risk factor for cardiovascular disease and renal disease." | ( Hernandez Schulman, I; Raij, L, 2006) |
| "Hypertension is a major cause of heart failure (HF) and is antecedent in 91% of cases." | ( Colon, P; Crow, R; Cutler, JA; Davis, BR; Dunn, K; Ellsworth, A; Franklin, S; Furberg, C; Goff, D; Golden, J; Leenen, F; Mohiuddin, S; Papademetriou, V; Piller, LB; Proschan, M, 2006) |
| "As hypertension is an important risk factor for renal allograft failure, we aimed to assess blood pressure control in renal transplant patients with deteriorating graft function using different methods of blood pressure measurements." | ( Gudmundsdottir, H; Os, I; Stenehjem, AE, 2006) |
| "Resistant hypertension is defined as blood pressure that remains above target levels despite treatment with three different antihypertensive agents." | ( Calhoun, DA; Gaddam, KK; Pratt-Ubunama, MN, 2006) |
| "Essential arterial hypertension is associated with polymorphisms in the AGT gene, M235T and T174M." | ( Jebeleanu, G; Pop, D; Procopciuc, LM; Zdrenghea, D, 2005) |
| "Post-operative hypertension is more likely in patients with a prior history of hypertension." | ( Pang, KP, 2006) |
| "Hypertension is a common cause of heart failure, and ventricular arrhythmias are a major cause of death in heart failure." | ( Altschuld, RA; Carnes, CA; Dech, SJ; Elton, TS; Lacombe, VA; McCune, SA; Sridhar, A, 2006) |
| "Posttransplant hypertension is a well-known risk factor for long-term allograft failure and mortality in kidney recipients." | ( Canbakan, B; Erbay, B; Erturk, S; Keven, K; Kutlay, S; Sengül, S; Yalçin, S, 2006) |
| "Hypertension is a major influence on the development of LVH." | ( Devereux, RB; Krauser, DG, 2006) |
| "Hypertension is associated with involvement of target organs which varies among the different ethnic groups." | ( Abuara'ar, T; Anfanger, S; Biton, A; Furman, T; Paran, E; Pilpel, D; Wolak, A; Wolak, T, 2007) |
| "Hypertension is prevalent in over 25% of populations in developed countries, and poses an increasing economic burden on health resources." | ( Ikeda, S; Ikegami, N; Sakamaki, Y; Saruta, T; Sasamura, H, 2006) |
| "The attenuation of hypertension is likely to be mediated by the corrected vascular dysfunction, whose precise mechanism and the possible clinical relevance remains to be studied further." | ( Cheng, ZJ; Jauhiainen, T; Korpela, R; Mervaala, EM; Pilvi, TK; Vapaatalo, H, 2006) |
| "Hypertension is a life-threatening disease that is associated with increased cardiovascular risks." | ( Wu, L, 2006) |
| "Hypertension is associated with abnormal neurohumoral activation." | ( Dawson, TA; Golding, S; Heaton, DA; Lei, M; Li, D; Mohan, RM; Paterson, DJ, 2006) |
| "Those with existing hypertension are more likely to see a blood pressure elevation, although the magnitude of the effect is less predictable and may vary with age, baseline blood pressure, type of NSAID and concurrent antihypertensive therapy." | ( Poulter, NR; Wilson, SL, 2006) |
| "Hypertension is rapidly reversible in the majority of heavy drinkers after the withdrawal of alcohol consumption." | ( Basan, L; Casaccio, D; Donnini, D; Esposito, W; Isola, M; Milocco, C; Sechi, LA; Soardo, G; Soldano, F; Varutti, R, 2006) |
| "Hypertension is more commonly diagnosed in older patients with atrial fibrillation than in the general population." | ( Fletcher, K; Hobbs, FD; Hurley, V; Ireson, R; Lip, GY; Mant, J, 2007) |
| "Hypertension is one of the most prevalent diseases in the developed and developing countries." | ( Ahmad, S; Iqbal, MZ; Khalid, N; Rahman, S; Zaidi, JH, 2006) |
| "Hypertension is a cardiovascular risk factor commonly associated with insulin resistance, the metabolic syndrome, and type 2 diabetes mellitus." | ( Appel, D; Benndorf, RA; Böger, RH; Maas, R; Rudolph, T; Schulze, F; Schwedhelm, E; Silberhorn, E, 2006) |
| "Hypertension is often associated clinically with diabetes as part of the insulin-resistance syndrome or as a manifestation of renal disease." | ( Cooper, ME; Jandeleit-Dahm, K, 2006) |
| "Hypertension is the second leading attributable cause of end-stage renal disease in the United States today." | ( Toto, RD, 2006) |
| "Endocrine hypertension is a term used for states in which hormone derangements result in clinically significant hypertension." | ( Cicala, MV; Mantero, F; Sartorato, P, 2006) |
| "Hypertension is one of the most distinguishing features of endogenous Cushing's syndrome, as it is present in about 80% of adult patients and in almost half of children and adolescents patients." | ( Chrousos, GP; Magiakou, MA; Smyrnaki, P, 2006) |
| "Nocturnal hypertension is associated with a high risk of morbidity and mortality." | ( Grossman, E; Kamari, Y; Laudon, M; Peleg, E; Sharabi, Y; Shen-Orr, Z; Yalcin, R; Zengil, H; Zisapel, N, 2006) |
| "Anaemia and hypertension are common in patients with chronic renal insufficiency." | ( Baptista, A; Carrasqueira, H; Faísca, M; Iglesias, A; Morgado, E; Neves, PL; Silva, AP; Soares, C, 2007) |
| "Hypertension is associated with increased reactive oxygen species (ROS)." | ( Beswick, RA; Brands, MW; Jin, L; Palmer, T; Pollock, DM; Pollock, JS; Taylor, TA; Webb, RC; Yamamoto, T, 2006) |
| "Essential hypertension is a major factor for myocardial infarction, heart failure and kidney failure." | ( Felder, RA; Jose, PA; Zeng, C, 2006) |
| "Essential hypertension is a common disease, yet its pathogenesis is not well understood." | ( Coffman, TM; Crowley, SD; Griffiths, R; Gurley, SB; Herrera, MJ; Kim, HS; Kumar, AP; Le, TH; Ruiz, P; Smithies, O, 2006) |
| "Essential hypertension is a heterogeneous multifactorial syndrome associated with a high cardiovascular risk." | ( Bianchi, G; Ferrandi, M; Ferrari, P; Manunta, P; Valentini, G, 2007) |
| "Essential hypertension is a complex multifactorial disease caused by ill-defined genetic factors." | ( Guruju, M; Kumar, A; Prater, A; Velez, DR; Vinukonda, G; Williams, SM, 2006) |
| "Essential hypertension is associated with several alterations in arterial function." | ( Kähönen, M; Kööbi, P; Mäki-Jouppi, J; Mustonen, J; Nordback, I; Pörsti, I; Sand, J; Tahvanainen, A; Taurio, J, 2006) |
| "Hypertension is a major risk factor for cardiovascular disease, and reduction of elevated blood pressure significantly reduces the risk of cardiovascular events." | ( Flammer, A; Hermann, M; Lüscher, TF, 2006) |
| "Severe hypertension is difficult to control." | ( Bhaumik, A; Franklin, SS; Lapuerta, P; Neutel, JM; Oparil, S; Ptaszynska, A, 2006) |
| "Arterial hypertension is the most frequent chronic disease and it is an important cause of morbidity and mortality in the developed world." | ( Egido, J; Gállego-Delgado, J; Lázaro, A; Osende, JI; Vivanco, F, 2007) |
| "Systemic hypertension is a major global problem contributing to enormous disease burden, premature morbidity and mortality." | ( Ram, CV, 2006) |
| "Essential hypertension is associated with enhanced biological activity of endothelin-1 (ET-1) and impaired endothelium-dependent vasodilatation." | ( Corti, R; Luscher, TF; Noll, G; Salvetti, A; Spieker, L; Sudano, I; Taddei, S; Virdis, A, 2007) |
| "People with prehypertension are at risk of developing hypertension, being a biomarker for cardiovascular disease risk." | ( Cadée, JA; Chang, CY; Chen, CW; Chen, SL; Huang, CN; Wang, CK, 2007) |
| "Essential hypertension is characterised by reduced pain sensitivity." | ( al'Absi, M; Beesley, L; Carroll, D; Edwards, L; France, CR; Martin, U; McIntyre, D; Ring, C, 2007) |
| "Hypertension is characterized by an endothelial dysfunction, possibly via reduced EDHF release and/or function." | ( Hilgers, RH; Webb, RC, 2007) |
| "Hypertension is associated with reduced cardiac vagal activity and decreased atrial guanylate cyclase and cGMP levels." | ( Almond, SC; Channon, KM; Dawson, TA; Heaton, DA; Li, D; Paterson, DJ; Wang, L, 2007) |
| "Resistant hypertension is a common medical disorder." | ( Epstein, M, 2007) |
| "Hypertension is a common condition that affects many people in the world." | ( Chehrei, A; Fani, A; Mashayekhim, N; Sadrnia, S; Samanianpour, P; Soltani, P, 2007) |
| "Hypertension is frequently associated with oxidative stress caused by high production of reactive oxygen species and compromised antioxidant defenses." | ( Blesa, S; Chaves, FJ; Gonzalez-Albert, V; Mansego, ML; Redon, J; Saez, G; Tormos, MC, 2007) |
| "Dialysis hypertension is a complex disorder in which ambient vascular resistance is too high for the blood volume." | ( Flanigan, MJ, 2007) |
| "Hypertension is related to an increased wall tension in the atria, resulting in increased stretch of the individual myocyte, which is one of the major stimuli for the remodeling process." | ( Frank, K; Müller-Ehmsen, J; Rana, OR; Reuter, H; Saygili, E; Schwinger, RH; Zobel, C, 2007) |
| "Hypertension is the most important cardiovascular risk factor for stroke." | ( de la Sierra, A, 2006) |
| "Essential hypertension is a disease multifactorially triggered by genetic and environmental factors." | ( Barros, M; Bittencourt, I; Cabello, PH; Cordovil, IL; Dolinsky, LC; Freitas, SR; Lima, AB; Moura-Neto, RS, 2007) |
| "Hypertension is a major risk factor leading to devastating cardiovascular events such as myocardial infarction, stroke, heart failure, and renal failure." | ( Wang, DH; Wang, Y, 2007) |
| "Hypertension is one of the most important risk factors for the development of cardiovascular disease." | ( White, WB, 2007) |
| "Hypertension is a common disease of the cardiovascular system." | ( Chen, L; Ding, YG; DU, JB; Ingrid, S; Liu, Y; Qi, JG; Tang, CS, 2007) |
| "Hypertension is one of the predominant risk factors for the progression of renal impairment, and the most common disorder in industrialized societies." | ( Tanemoto, M, 2007) |
| "Essential hypertension is characterized by endothelial dysfunction, arterial stiffness, and increased oxidative stress." | ( Franzoni, F; Ghiadoni, L; Giannarelli, C; Magagna, A; Plantinga, Y; Salvetti, A; Taddei, S, 2007) |
| "Hypertension is frequently associated with obesity and natriuretic peptide levels are reported to decrease in obese subjects." | ( Cikim, AS; Tekes, S, 2007) |
| "Prehypertension is a recognized stage of blood pressure but treatment standards have not yet been established." | ( Nesbitt, SD, 2007) |
| "Hypertension is an increasing public health problem all over the world." | ( Baráth, A; Bereczki, C; Endreffy, E; Gellén, B; Németh, I; Szücs, B; Túri, S, 2007) |
| "Hypertension is an important public health problem affecting more than 50 million individuals in the USA alone." | ( Citterio, L; Ferrandi, M; Lanzani, C; Manunta, P, 2007) |
| "Hypertension is an important risk factor associated with development and progression of diabetic retinopathy (DR)." | ( Biswas, SK; de Faria, JB; de Faria, JM; Pinto, CC; Silva, KC; Souza, DS, 2007) |
| "Hypertension is an important risk factor for cardiovascular diseases." | ( Cheung, BM; Leung, RY; Ong, KL; Wong, LY, 2007) |
| "Hypertension is associated with vascular remodeling characterized by rearrangement of extracellular matrix proteins." | ( Chatziantoniou, C; Dubroca, C; Dussaule, JC; Esposito, B; Flamant, M; Lehoux, S; Lopes, I; Placier, S; Tedgui, A, 2007) |
| "Cold-induced hypertension is induced in rats after repeated exposure to cold." | ( Chang, D; He, LH; Liu, TT; Shi, HM; Wang, S; Ye, KP; Zhang, Y, 2007) |
| "Hypertension is the most significant complication from treatment with erythropoietin (Epo)." | ( Lee, JS; Lee, JY; Lee, MS, 2007) |
| "Hypertension is a likely consequence of chronic lead exposure in humans, especially in association with reduced renal function and in high risk populations." | ( Bravo, Y; Ferrebuz, A; Quiroz, Y; Rodríguez-Iturbe, B; Vaziri, ND, 2007) |
| "Although control of hypertension is established as an important factor in the primary and secondary prevention of stroke, management of blood pressure in the setting of acute ischemic stroke remains controversial." | ( Wityk, RJ, 2007) |
| "Prevalence of hypertension is much higher among diabetic than non-diabetic patients, and the hypertensive patient is more likely to develop type 2 diabetes." | ( García Donaire, JA; Ruilope, LM, 2007) |
| "Hypertension is an independent risk factor for peripheral arterial disease." | ( Hui, R; Sun, K; Wu, H; Yang, X; Zhang, H; Zhang, W, 2007) |
| "Hypertension is the most common reason for visits to physicians' offices and the primary reason for prescription drug use." | ( Houston, MC, 2007) |
| "Although hypertension is recognized as one of the most serious consequences of obesity, its pathophysiology remains incompletely understood." | ( Freeman, RH; Mathew, B; Patel, SB; Reams, GP; Spear, RM; Villarreal, D, 2007) |
| "Arterial hypertension is one of the major coronary risk factors for cardiovascular diseases." | ( Kawecka-Jaszcz, K; Pośnik-Urbańska, A, 2006) |
| "Hypertension is a major risk factor for cardiovascular disease." | ( Baba, Y; Fukuo, K; Higuchi, M; Kawamoto, H; Maeda, N; Ogihara, T; Ozaki, T; Rakugi, H; Yasuda, O; Yotsui, T, 2007) |
| "Hypertension is one of the most common cardiovascular risk factors." | ( Abts, M; Kastrati, D; Schühlen, H, 2007) |
| "Hypertension is present in nearly 80% of dialysis patients yet adequately controlled in less than half." | ( Coyne, DW; Nath, V; Zheng, S, 2007) |
| "Neonatal hypertension is an uncommon but important complication of intensive care management." | ( Falk, MC; Kent, AL; Seliem, WA; Shadbolt, B, 2007) |
| "Hypertension is associated with inward remodeling of small arteries and decreased erythrocyte deformability, both impairing proper tissue perfusion." | ( Bakker, EN; Hardeman, MR; Pistea, A; Spaan, JA; van Rooijen, N; VanBavel, E, 2008) |
| "Essential hypertension is a complex disease with both genetic and environmental determinants." | ( Kasacka, I; Majewski, M, 2007) |
| "Hypertension is commonly observed in alcoholics." | ( Brecher, AS; Dubord, R, 2008) |
| "Hypertension is a common complication in autosomal dominant polycystic kidney disease (ADPKD)." | ( Poliak, R; Schmieder, RE; Schulze, BD; Stiasny, B; Zeltner, R, 2008) |
| "Pediatric hypertension is urgently increasing in Greece." | ( Malindretos, P; Mavromichalis, I; Papandreou, D; Rousso, I; Stamou, M, 2007) |
| "Hypertension is the most important risk factor in strokes, representing roughly 70% of all cases." | ( Ahmed, M; Corrêa, Mde C; da Rosa, CS; Kaizer, RR; Lunkes, DS; Lunkes, G; Maldonado, P; Morsch, VM; Pereira, ME; Schetinger, MR, 2008) |
| "Hypertension is a common condition associated with considerable morbidity and mortality." | ( Ram, CV; Rudmann, MA, 2007) |
| "Prehypertension is common in minority women." | ( Agyemang, C; Stronks, K; van den Born, BJ; van Valkengoed, I, 2007) |
| "1." | ( Hatai, A; Kato, J; Kurasaki, M; Mukai, Y; Sagai, M; Sato, S; Yamate, J, 2008) |
| ": Hypertension is a cardiovascular risk factor commonly associated with endothelial dysfunction and increased renal vascular resistance." | ( Appel, D; Benndorf, RA; Böger, RH; Maas, R; Schwedhelm, E; Wenzel, UO, 2007) |
| "Essential hypertension is a major cause of cardiovascular morbidity and mortality in the Western world." | ( Papademetriou, V; Papadopoulos, DP, 2007) |
| "Resistant hypertension is an important clinical problem that is poorly studied and not well managed." | ( Beck, GR; Bisognano, JD; Filippone, JD; Fong, MW; Katz, MG, 2007) |
| "Hypertension is commonly identified based on the average of two BPs taken at each of two visits, a practice consistent with current guidelines." | ( Turner, MJ; van Schalkwyk, JM, 2008) |
| "Salt-sensitive (SS) hypertension is a vascular diathesis characterized by reduced cardiovascular and renal nitric oxide bioavailability and local upregulation of ANG II." | ( Jaimes, EA; Pearse, DD; Puzis, L; Raij, L; Zhou, MS, 2008) |
| "Hypertension is a perplexing multiorgan disease involving renal primary pathology and enhanced angiotensin II vascular reactivity." | ( Amberg, GC; Lederer, WJ; McKnight, GS; Navedo, MF; Nieves-Cintrón, M; Santana, LF; Votaw, VS; Yuan, C, 2008) |
| "Resistant hypertension is defined as blood pressure that remains uncontrolled despite using at least three antihypertensive medications in effective doses, ideally including a diuretic." | ( Calhoun, DA; Pimenta, E, 2007) |
| "Hypertension is a common treatable risk factor for cardiovascular disease." | ( Krzesinski, JM; Scheen, AJ, 2007) |
| "Hypertension is one of the major side-effects of this drug, and reported incidences vary substantially between clinical trials." | ( Chen, JJ; Kudelka, A; Lu, J; Wu, S; Zhu, X, 2008) |
| "Essential hypertension is characterized by an increased risk of thrombus formation, and by an inhibition of intraplatelet NO bioactivity." | ( Brunini, TM; da Silva, MN; de Meirelles, LR; Ellory, JC; Mann, GE; Mendes, MA; Mendes-Ribeiro, AC, 2009) |
| "Hypertension is a risk factor for cardiovascular disease and outcomes in women." | ( Dahlöf, B; Devereux, RB; Franco, V; Gerdts, E; Hille, DA; Kjeldsen, SE; Lyle, PA; Manhem, K; Okin, PM; Oparil, S; Os, I, 2008) |
| "Hypertension is frequently found in endogenous Cushing's Syndrome (CS)." | ( Armigliato, M; Cuppini, S; Mazza, A; Pessina, AC; Rempelou, P; Rubello, D; Zamboni, S; Zennaro, R, 2008) |
| "Hypertension is one of the risk factors for cardiovascular diseases." | ( Bachorzewska-Gajewska, H; Dobrzycki, S; Malyszko, J; Malyszko, JS; Pawlak, K, 2008) |
| "Hypertension is associated with kidney injury as reflected by elevated serum NGAL and cystatin C." | ( Bachorzewska-Gajewska, H; Dobrzycki, S; Malyszko, J; Malyszko, JS; Pawlak, K, 2008) |
| "Hypertension is a risk factor for atherothrombotic vascular events." | ( Badimon, L; Costales, P; Huesca-Gómez, C; Llorente-Cortés, V; Sendra, J, 2008) |
| "Established hypertension is characterized by increased peripheral vascular resistance and endothelial dysfunction, features that may underlie the reduced exercise-induced vasodilatation seen in hypertensive patients." | ( Attinà, TM; Malatino, LS; Maxwell, SR; Padfield, PL; Webb, DJ, 2008) |
| "Therefore, hypertension is associated with a decrease in the number of circulating progenitor cells and in the BM-MNC proangiogenic potential, probably leading to vascular complications in this setting." | ( Cochain, C; Duriez, M; Lévy, BI; Loinard, C; Mees, B; Silvestre, JS; Vilar, J; You, D, 2008) |
| "We conclude that hypertension is prevalent in the living renal allografts recipients." | ( Amar, Y; Bayahia, R; Benamar, L; Faik, M; Laboudi, A; Ouzeddoun, N; Rhou, H; Sqalli, TH, 2008) |
| "Smoking and hypertension are known causes of stroke and dementia." | ( Elmståhl, S; Reinprecht, F; Siennicki-Lantz, A; Wollmer, P, 2008) |
| "Prehypertension is considered a precursor of stage 1 hypertension and a predictor of excessive cardiovascular risk." | ( Umemura, S, 2008) |
| "Resistant hypertension is defined as blood pressure (BP) that remains uncontrolled in spite of the use of >/=3 antihypertensive medications." | ( Gaddam, KK; Oparil, S; Pimenta, E, 2008) |
| "Arterial hypertension is a global public health problem owing to its high prevalence and association with increased risk for cerebral, cardiac and renal events." | ( Celoria, BM; Francischetti, A; Francischetti, EA; Genelhu, VA, 2008) |
| "Hypertension is a major risk factor for cardiovascular morbidity and mortality and currently has been estimated at 30% of the US population." | ( Chrysant, SG, 2008) |
| "Hypertension is one of the most serious health problems of the modern world with a continuous rise in the number of patients." | ( Bariwal, JB; Chauhan, BS; Jain, KS; Kathiravan, MK; Phoujdar, MS; Sahne, RS; Shah, AK; Yadav, MR, 2008) |
| "Hypertension is considered a low-grade inflammatory condition induced by various proinflammatory cytokines, including tumor necrosis factor (TNF)-alpha." | ( Francis, J; Haque, M; Majid, DS; Sriramula, S, 2008) |
| "Hypertension is a major cardiovascular risk factor but most patients remain asymptomatic for many years." | ( Papademetriou, V; Wojciechowski, D, 2008) |
| "Hypertension is a major risk factor for cardiovascular disease, and data regarding the efficacy and tolerability of telmisartan compared with losartan on blood pressure (BP) control in patients with hypertension." | ( Cheng, JW; Lu, GC; Xi, GL, 2008) |
| "Hypertension is associated with impaired cognitive function but the effect of antihypertensive treatment on cognitive function is unclear." | ( Ford, GA; Harrington, F; McKeith, IG; Saxby, BK; Wesnes, KA, 2008) |
| "Hypertension is associated with high cardiovascular risk." | ( Britz, S; Landsiedel, L; Lohmann, T; Thiele, S; Wallaschofski, H, 2008) |
| "Hypertension is a cardiovascular disease associated with increased plasma catecholamines, overactivation of the sympathetic nervous system, and increased vascular tone and total peripheral resistance." | ( Adams, ME; DeFino, MC; Feller, DB; Hague, C; Hertz, AL; Lyssand, JS; Tang, XB; Wacker, JL, 2008) |
| "Hypertension is a direct consequence of inhibiting VEGF signaling but can be controlled with appropriately selected, standard antihypertensive medication." | ( Curwen, JO; Kendrew, J; Musgrove, HL; Ogilvie, DJ; Richmond, GH; Wedge, SR, 2008) |
| "ACTH-induced-hypertension is commonly employed as a model of stress-related hypertension, and despite extensive investigation, the mechanisms underlying elevated blood pressure (BP) are not well understood." | ( Dostanic-Larson, I; Lasko, V; Lingrel, JB; Loreaux, EL; Lorenz, JN; Paul, RJ; Schnetzer, JR, 2008) |
| "Hypertension is one of the major risk factors for cardiovascular morbidity and mortality." | ( Grossman, E, 2008) |
| "Hypertension is a leading cause of death worldwide, and a major public health problem in Canada." | ( Curnew, GP; Leclerc, JM; Rehel, B; Tardif, JC, 2008) |
| "The arterial hypertension is a disorder characterized by relevant alterations in the bone tissue." | ( Chin, CM; Faig-Leite, H; Fernandes, RG; Nobre, MD, 2008) |
| "Hypertension is associated with mild decrements in cognition." | ( Christie, IC; Jennings, JR; Meltzer, CC; Muldoon, MF; Price, J, 2008) |
| "Aging and hypertension are two independent cardiovascular risk factors that have been shown to exhibit increased endothelin-1 system activation." | ( DeSouza, CA; Stauffer, BL; Westby, CM, 2008) |
| "Resistant hypertension is a common clinical problem and greatly increases the risk of target organ damage." | ( Aban, I; Calhoun, DA; Gaddam, KK; Nishizaka, MK; Oparil, S; Pimenta, E; Pratt-Ubunama, MN, 2008) |
| "Hypertension is a major health problem worldwide, yet remains under-diagnosed and under-treated." | ( Smith, DH, 2008) |
| "Hypertension is one of the main cardiovascular risk factors, and it may be responsible for the excess morbidity and mortality in postmenopausal women." | ( Fábián, E; Farkas, K; Nagy, L, 2008) |
| "As arterial hypertension is the most important risk factor for ischemic stroke, the relevant guidelines recommend rigorous treatment to normalize blood pressure." | ( Bestehorn, K; Diener, HC; Haller, H; Jung, C; Lüders, S; Schmieder, RE; Schrader, J; Smolka, W; Wahle, K, 2008) |
| "Hypertension is one of the most frequent complication during laryngoscopy and intubation; thus in the premedication or induction stages, many drugs have been used to control this hypertension." | ( Firoozbakhsh, F; Khashayar, P; Mohammadi, FH; Safari, S, 2008) |
| "Hypertension is an important risk factor for cardiovascular disease (CVD), particularly in patients with comorbid obesity, diabetes, metabolic disease, or end-organ damage." | ( Ruilope, LM; Segura, J, 2008) |
| "Acute postoperative hypertension is a well-known complication of cardiac surgery and is associated with postoperative morbidity." | ( Aronson, S; Corwin, HL; Gandhi, SD; Lumb, PD; Newman, MF; Singla, N; Sladen, RN; Warltier, DC, 2008) |
| "Hypertension is a lifestyle-related disease which often leads to serious conditions such as heart disease and cerebral hemorrhage." | ( Fukamizu, A; Ichino, T; Ishida, J; Koyama, T; Matsumoto, H; Mura, E; Nakamura, K; Ohno, O; Ohno, T; Uemura, D; Yamada, K; Yamaguchi, K; Yazawa, K; Ye, M, 2008) |
| "Hypertension is a serious medical problem affecting millions of people worldwide." | ( Rotin, D; Schild, L, 2008) |
| "Untreated hypertension is self-accelerating condition through RAS stimulation." | ( Horiuchi, M; Inaba, S; Iwai, M, 2008) |
| "Prevention of hypertension is one of the important strategies for decreasing future cardiovascular accidents." | ( Inoue, T; Ohya, Y, 2008) |
| "Low-renin hypertension is a common type of resistant hypertension and is often associated with increased sodium retention." | ( Brown, MJ; Mackenzie, IS, 2009) |
| "Hypertension is more common in men than in women of the same age." | ( Dezhai, Y; Jinzhen, W; Ruixing, Y; Shangling, P; Weixiong, L; Yuming, C, 2008) |
| "Hypertension is one of its major side effects with a substantial variation in the reported incidences among clinical studies." | ( Stergiopoulos, K; Wu, S; Zhu, X, 2009) |
| "Hypertension is a major modifiable risk factor, and while sodium restriction in hypertensive patients appears effective, its role in normotensive individuals remains unclear." | ( Chaturvedi, N; Hatcher, J; Jafar, TH; Jessani, S, 2008) |
| "Hypertension is a highly prevalent disease and a strong risk factor for cardiovascular disease in industrialized countries in Europe and North America." | ( Kékes, E, 2008) |
| "Systemic hypertension is a major drawback associated with fast tracking, which may predispose to formation of intracranial hematoma." | ( Bhagat, H; Bithal, PK; Chouhan, RS; Dash, HH; Pandia, MP, 2008) |
| "Hypertension is an uncommon but significant problem in high-risk neonates and infants, and the spectrum of potential causes is broad." | ( Chen, CM; Chen, JM; Chiu, SY; Hwang, B; Jeng, MJ; Lee, YS; Soong, WJ; Tang, RB, 2008) |
| "Perioperative hypertension is commonly encountered in patients that undergo surgery." | ( Marik, PE; Varon, J, 2008) |
| "Hypertension is a common comorbidity (34%), whereas early nephropathy appears to be rare (4%)." | ( Barrett, TG; Haines, L; Lynn, R; Shield, JP; Wan, KC, 2009) |
| "Hypertension is a chronic condition associated with an increased risk of mortality and morbidity." | ( Bassett, K; Fortin, PM; Musini, VM; Wright, JM, 2008) |
| "Arterial hypertension is one of the major risk factors for the development of cardiovascular diseases such as heart failure, ischemic heart disease, chronic kidney disease and cerebrovascular events." | ( Santamaría Olmo, R, 2008) |
| "Salt-sensitive hypertension is common in the aged population." | ( Bennink, MR; Bolling, SF; Kaufman, PB; Kirakosyan, A; Parikh, RV; Seymour, EM; Singer, AA, 2008) |
| "Hypertension is a major risk factor for stroke, but the factors that contribute to the increased incidence and severity of ischemic stroke in hypertension remain to be determined." | ( Dunn, KM; Falck, J; Flasch, AK; Harder, DR; Renic, M; Roman, RJ, 2008) |
| "The extent to which hypertension is influenced by traditional CVD risk factors as well as by some SES indicators was also assessed using a forward stepwise method of the multivariate logistic analysis." | ( Barbalić, M; Janićijević, B; Klarić, IM; Lauc, LB; Narancic, NS; Salihović, MP; Skarić-Jurić, T; Starcević, B; Zeljko, H, 2008) |
| "Hypertension is the main haemodynamic factor." | ( Bosnjak, I; Kosović, P; Radić, R; Selthofer, R; Selthofer-Relatić, K; Vcev, A; Vizjak, V, 2008) |
| "Hypertension is common after HT; however, in most patients, it can be controlled with a single antihypertensive agent." | ( Almenar Bonet, L; Fuentes, FB; Manchón, JN; Martínez-Dolz, L; Moro López, J; Pérez, OC; Ramón-Llín, JA; Sánchez Gómez, JM; Sánchez Lázaro, IJ; Sanz, AS; Soriano, JR, 2008) |
| "Hypertension is a common problem in older cats, particularly associated with chronic kidney disease (CKD)." | ( Elliott, J; Syme, HM; Walker, DJ, 2009) |
| "Hypertension is a known risk factor for cardiovascular disease." | ( Bärtschi, C; Ehlert, U; Redwine, LS; von Känel, R; Wirtz, PH, 2009) |
| "Essential hypertension is characterized by reciprocal relations between endothelial dysfunction and insulin resistance." | ( Crandon, SK; Hall, G; Karne, RJ; Kolodziej, TL; Muniyappa, R; Quon, MJ, 2008) |
| "Hypertension is a leading risk factor for the development and progression of diabetic retinopathy and contributes to a variety of other retinal diseases in the absence of diabetes mellitus." | ( Bursell, SE; Chilcote, TJ; Clermont, AC; Feener, EP; Phipps, JA; Sinha, S, 2009) |
| "Hypertension is a highly prevalent disease and one of the most important modifiable risk factors for cardiovascular disease." | ( Pimenta, E, 2009) |
| "Hypertension is a major risk factor for cardiovascular disease and is highly prevalent in women with SLE." | ( Ryan, MJ, 2009) |
| "Secondary hypertension is an elevated blood pressure resulting from an underlying and identifiable cause." | ( Sakihara, S, 2008) |
| "Hypertension is associated with cerebrovascular remodeling and endothelial dysfunction, which may reduce cerebral vasomotor reactivity to CO2." | ( Claassen, JA; Levine, BD; Zhang, R, 2009) |
| "Hypertension is closely associated with erectile dysfunction (ED) as it has been observed in many experimental models of hypertension." | ( Dorrance, AM; Leite, R; Linder, AE; Mills, TM; Webb, RC, 2009) |
| "Essential hypertension is a major risk factor for stroke, myocardial infarction, and heart and kidney failure." | ( Jose, PA; Villar, VA; Yu, P; Zeng, C; Zhou, L, 2009) |
| "Essential hypertension is a clinical condition associated with insulin resistance and progressive impairment of renal function that increases cardiovascular events." | ( Andreozzi, F; Laino, I; Maio, R; Mazzaferro, D; Miceli, S; Pascale, A; Perticone, F; Perticone, M; Sciacqua, A, 2009) |
| "Hypertension is a leading contributor to the burden of cardiovascular disease." | ( Oparil, S; Weber, M, 2009) |
| "Hypertension is a major risk factor for the development of cardiovascular and renal disease." | ( Sureshkumar, KK, 2008) |
| "Hypertension is a major risk factor for cardiovascular disease that contributes to the premature death of millions of people each year, and identification and treatment of hypertension continues to be a challenge." | ( Ruilope, LM, 2008) |
| "Hypertension is a global condition affecting billions worldwide." | ( Nuzum, DS; Snider, ME; Veverka, A, 2008) |
| "Vasopressor-induced hypertension is routinely indicated for prevention and treatment of cerebral vasospasm (CVS) after subarachnoid haemorrhage (SAH)." | ( Fandino, J; Fathi, AR; Hidalgo Staub, ET; Jakob, SM; Marbacher, S; Neuschmelting, V; Schroth, G; Takala, J, 2009) |
| "Since hypertension is often a feature of the "metabolic", insulin resistance syndrome, which in turn affects both fibrinogen kinetics and whole-body protein turnover, we selected hypertensive subjects without the metabolic syndrome." | ( Baiocchi, MR; Coracina, A; Kiwanuka, E; Millioni, R; Puricelli, L; Semplicini, A; Tessari, P; Vettore, M; Zaramella, M, 2009) |
| "Arterial hypertension is an important cardiovascular risk factor." | ( Krzesinski, JM; Scheen, AJ, 2009) |
| "Hypertension is associated with endothelial dysfunction and decreased bioavailability of nitric oxide (NO)." | ( Weber, MA, 2009) |
| "Resistant hypertension is found in an important and rapidly growing subset of the hypertensive population, and data characterizing this group of patients are limited." | ( Acelajado, MC; Calhoun, DA, 2009) |
| "Hypertension is the leading cause of cardiovascular diseases, and an estimated 972 million people in the world are suffering from this problem." | ( Hui, RT; Li, YF; Xiao, CS, 2009) |
| "The cause for the hypertension is unknown." | ( Baum, M; Dagan, A; Dwarakanath, V; Gattineni, J; Habib, S, 2009) |
| "Hypertension is associated with an increase in vasoactive peptides, but conflicting results are reported concerning their causes of elevation." | ( Ayadi, I; Drissa, H; Feki, M; Kaabachi, N; Mebazaa, A; Omar, S; Soualmia, H, 2009) |
| "Isolated systolic hypertension is an important risk factor for cardiovascular disease and results primarily from elastic artery stiffening." | ( Brown, MJ; Cockcroft, JR; Dhakam, Z; Mackenzie, IS; McEniery, CM; Wilkinson, IB, 2009) |
| "Hypertension is a key risk factor for stroke, cardiovascular disease and dementia." | ( Archbold, GP; McNulty, H; Mueller, H; Murphy, A; Myint, PK; Patterson, CC; Rea, IM, 2009) |
| "Nocturnal hypertension is a common complication of essential and secondary hypertension." | ( Peixoto, AJ; Vij, R, 2009) |
| "Hypertension is a health threat which, so far, is not successfully managed, despite the availability of effective drug treatment." | ( Bramlage, P, 2009) |
| "Hypertension is one of the major risk factors for cardiovascular diseases." | ( Cai, H; Chen, HZ; Chen, JZ; Huang, Y; Hui, RT; Li, HL; Liang, CC; Liu, DP; Liu, G; Lv, X; Ma, TM; Sun, LH; Wei, YS; Yang, RF; Zhang, R; Zhuo, ML, 2009) |
| "Although arterial hypertension is a powerful predictor of graft failure, only few studies have evaluated 24-hr blood pressure (BP) profile in renal transplant recipients (RTRs)." | ( Amidone, M; Cannella, G; Gherzi, M; Massarino, F; Paoletti, E, 2009) |
| "In conclusion, hypertension is characterized by a decline in endothelial function, associated with a progressive decrease in NO bioavailability and increase in the production of EDCF." | ( Daghini, E; Ghiadoni, L; Taddei, S; Versari, D; Virdis, A, 2009) |
| "Hypertension is one of the most important risk factors for, and causes of, cardiovascular disease." | ( Bellocci, F; D'Orazio, N; Riccioni, G; Vitulano, N, 2009) |
| "Systemic hypertension is associated with increased ET-1 and ET(A) receptor mRNA expression, whereas insulin-dependent diabetes down-regulates ET(A) receptor mRNA expression in the internal mammary artery in patients with coronary artery disease undergoing bypass grafting." | ( Kaklamanis, L; Koutouzis, M; Kyriakides, ZS; Lianidou, ES; Lolaka, M; Nikolaou, N; Zygalaki, E, 2009) |
| "Hypertension is a significant cause of chronic renal injury and its effective treatment is capable of reducing the rate of renal failure." | ( Caradonna, M; Cardillo, M; Di Pasquale, P; La Rocca, G; Licata, G; Mezzero, M; Parrinello, G; Paterna, S; Torres, D; Trapanese, C, 2009) |
| "Endocrine hypertension is rare, but frequently refractory." | ( Ibsen, H; Poulsen, PL, 2009) |
| "Hypertension is strongly associated with increased risk of subsequent heart failure." | ( Andersen, NH; Svendsen, TL; Wachtell, K, 2009) |
| "Although hypertension is common (30% of adults in the USA), its control to recommended blood pressure levels of under 140/90 mmHg remains low, at 36." | ( Chrysant, SG, 2009) |
| "1." | ( Adithan, C; Balachander, J; Dutta, TK; Rajan, S; Ramu, P; Shewade, DG; Swaminathan, RP, 2009) |
| "Hypertension is one of the most common diseases that induce a series of pathological changes in different organs of the human body, especially in the heart." | ( Li, X; Shimada, T; Zhang, Y; Zhao, L; Zhou, X, 2009) |
| "Hypertension is one of the major risk factors for cardiovascular disease." | ( Elisaf, MS; Liberopoulos, EN; Rizos, CV, 2009) |
| "Hypertension is a major determinant of progression of CKD." | ( Beilin, L; Burke, V; Cowpland, CA; Dogra, G; Irish, A; Mori, TA; Puddey, I; Watts, GF, 2009) |
| "Hypertension is more common among men at younger ages and among women after age 60, suggesting a possible link between endogenous estrogens and systolic blood pressure (SBP)." | ( Cacioppo, JT; Hawkley, LC; Masi, CM; Veenstra, TD; Xu, X, 2009) |
| "Obesity and hypertension are the two major risk factors that contribute to the progression of end-stage renal disease." | ( Elmarakby, AA; Imig, JD, 2010) |
| "Supine hypertension is difficult to manage in patients with pure autonomic failure (PAF), because treatment can worsen orthostatic hypotension." | ( Biaggioni, I; Black, BK; Davis, TL; Gamboa, A; Garland, EM; Okamoto, L; Raj, SR; Robertson, D, 2009) |
| "Hypertension is associated with remodeling and mechanical alterations of resistance arteries." | ( Baskurt, OK; Gündüz, F; Meiselman, HJ, 2009) |
| "Hypertension is commonly associated with chronic renal disease in cats, and inappropriate activation of the renin-angiotensin-aldosterone system (RAAS) may contribute to the hypertensive state." | ( Henik, RA; Steele, JL; Stepien, RL, 2002) |
| "Hypertension is an important risk factor for the progression of chronic renal disease, which may result in the development of end-stage renal disease." | ( Bakhshi, E; Golab, F; Kadkhodaee, M; Seifi, B; Zahmatkesh, M, 2009) |
| "Hypertension is a mechanism-based toxicity of sorafenib and other cancer therapeutics that inhibit the vascular endothelial growth factor (VEGF) signaling pathway." | ( Black, HR; Elliott, WJ; Karrison, T; Kasza, KE; Maitland, ML; Moshier, K; Ratain, MJ; Sit, L; Stadler, WM; Undevia, SD, 2009) |
| "Hypertension is characterized by endothelial dysfunction and increased risk for adverse cardiovascular outcomes." | ( Siragy, HM, 2010) |
| "Considering that hypertension is a modifiable risk factor, the understanding of its epidemiology and pathophysiology and the development of appropriate therapeutic strategies are conceivably crucial in reducing cardiovascular risk." | ( Taddei, S, 2009) |
| "Hypertension is a risk factor for PAD." | ( Lane, DA; Lip, GY, 2009) |
| "Hypertension is associated with an increased risk of stroke, myocardial infarction and congestive heart failure." | ( Mah, GT; Musini, VM; Tejani, AM, 2009) |
| "Hypertension is a commonly measured surrogate marker for non-fatal and fatal cardiovascular endpoints such as heart attacks and strokes." | ( Bellusci, A; Ho, MJ; Wright, JM, 2009) |
| "Because hypertension is an important risk factor for preeclampsia, we investigated whether hypertensive mice that overexpress human renin and angiotensinogen develop superimposed preeclampsia." | ( Cloutier, G; Falcao, S; Gutkowska, J; Lavoie, JL; Maurice, RL; Stoyanova, E, 2009) |
| "Hypertension is a well-known risk factor for various cardiovascular diseases." | ( Agarwal, D; Francis, J; Haque, M; Mariappan, N; Pariaut, R; Sriramula, S, 2009) |
| "Hypertension is a major risk factor for cardiovascular disease." | ( Aoyagi, Y; Kato, K; Metoki, N; Nozawa, Y; Oguri, M; Satoh, K; Watanabe, S; Yamada, Y; Yokoi, K; Yoshida, H; Yoshida, T, 2010) |
| "Hypertension is a widely accepted risk factor for coronary artery disease (CAD), chronic heart failure, and chronic kidney disease (CKD)." | ( Bachórzewska-Gajewska, H; Dobrzycki, S; Małyszko, J; Mysliwiec, M; Poniatowski, B, 2009) |
| "Hypertension is caused by various factors and the predominant causes include an increase in cholesterol levels, incidence of diabetes, inconsistent modulation of renin and imbalanced sexual hormones." | ( Ewe, JA; Fung, WY; Kuan, CY; Liong, MT; Lye, HS, 2009) |
| "Hypertension is associated with cognitive decline in elderly persons." | ( Antequera, M; Antúnez, C; Campoy, G; Carrillo, A; Fuentes, LJ; García Santos, JM; García-Sevilla, J; Ortega, G; Torres del Río, S; Vidal, JB, 2010) |
| "Hypertension is a risk factor for the two leading causes of death in renal transplant recipients: cardiovascular disease (CVD) and graft failure." | ( Geiger, H; Heemann, U; Legendre, C; Lièvre, M; Martinez, F; Moulin, B; Mourad, G; Philipp, T; Schmieder, R, 2010) |
| "Ageing and hypertension are the major risk factors for the development of cardiovascular and renal diseases, and the renin-angiotensin system has been shown responsible for these pathologies." | ( Grujić-Milanović, J; Ivanov, M; Jovović, D; Mihailović-Stanojević, N; Miloradović, Z, 2009) |
| "PURPOSE Hypertension is a commonly reported adverse effect after administration of vascular endothelial growth factor (VEGF) inhibitors." | ( Blum, HE; De Bono, J; Drevs, J; Fiedler, W; Fielding, A; Hoekman, K; Langenberg, MH; Le Maulf, F; Robertson, J; Schellens, JH; Unger, C; van Herpen, CM; Voest, EE, 2009) |
| "Obesity and hypertension are risk factors for the development of chronic kidney disease." | ( Imig, JD; Knight, SF; Roy, S; Yuan, J, 2010) |
| "Chronic hypertension is characterized by a persistent increase in vascular tone." | ( Bertorello, AM; Jaitovich, A, 2010) |
| "Hypertension is common following renal transplantation." | ( Barcellos, FC; Bohlke, M; Gomes, RH; Marini, SS; Rocha, M; Terhorst, L, 2009) |
| "Hypertension is both the cause and effect of kidney disease." | ( Lubanski, MS; McCullough, PA, 2009) |
| "Hypertension is a common condition that is a well-described risk factor for the development of cerebrovascular disease, myocardial infarction and heart failure." | ( Sheppard, R, 2010) |
| "Hypertension is a common risk factor for peripheral arterial disease (PAD)." | ( Anderson, RD; Bavry, AA; Cooper-Dehoff, RM; Denardo, SJ; Gong, Y; Handberg, EM; Pepine, CJ, 2010) |
| "Patients with hypertension are at increased risk for nephrolithiasis and those with nephrolithiasis are at risk for hypertension." | ( Bechis, SK; Eisner, BH; Porten, SP; Stoller, ML, 2010) |
| "Arterial hypertension is an independent risk factor for cardiovascular diseases and one of the major causes for mortality worldwide." | ( Savvatis, K; Schultheiss, HP; Tschöpe, C; Westermann, D, 2009) |
| "Hypertension is an independent determinant of cardiovascular risk, a phenotype that usually has a strong genetic component." | ( Bhaskar, LV; Non, AL; Pardhasaradhi, G; Praveen Kumar, K; Rao, VR; Singh, L; Thangaraj, K, 2010) |
| "The prevalence of hypertension is increased in winter and in cold regions of the world." | ( Sun, Z, 2010) |
| "Hypertension is a known risk factor for renal cell carcinoma (RCC), although the underlying biological mechanisms of its action are unknown." | ( Andreotti, G; Bencko, V; Berndt, SI; Boffetta, P; Brennan, P; Chanock, SJ; Chow, WH; Janout, V; Karami, S; Kollarova, H; Mates, D; Matteev, V; Menashe, I; Moore, LE; Navratilova, M; Rosenberg, PS; Rothman, N; Szeszenia-Dabrowska, N; Yeager, M; Zaridze, D, 2010) |
| "Hypertension is a common side effect in cancer patients treated with inhibitors of vascular endothelial growth factor/vascular endothelial growth factor receptor-2 signaling and may represent a marker of clinical benefit." | ( Boven, E; de Boer, MP; Eringa, EC; Serné, EH; Smulders, YM; van den Eertwegh, AJ; van der Veldt, AA; van Hinsbergh, VW, 2010) |
| "Hypertension is associated with endothelial dysfunction and increased cardiovascular risk." | ( Chae, IH; Chang, HJ; Cho, YS; Choi, DJ; Kim, CH; Kim, HS; Kim, KI; Oh, BH; Park, YB; Suh, JW; Youn, TJ, 2010) |
| "Arterial hypertension is one of the major diseases in industrial countries and a major cause of mortality." | ( Friebe, A; Groneberg, D; Koesling, D; König, P; Offermanns, S; Wirth, A, 2010) |
| "Hypertension is a global disease that affects more than 1 billion people worldwide and 75 million people in the USA." | ( Bergese, SD; Puente, EG, 2010) |
| "Essential hypertension is associated with increased risk of arterial thrombotic disease." | ( Douma, S; Ferro, A; Gkaliagkousi, E; Passacquale, G; Zamboulis, C, 2010) |
| "Hypertension is one of the most frequent pathologies in the industrialized world." | ( Brégeon, J; Bril, A; Guilluy, C; Henrion, D; Loirand, G; Loufrani, L; Offermanns, S; Pacaud, P; Retailleau, K; Rolli-Derkinderen, M; Scalbert, E; Torres, RM; Toumaniantz, G, 2010) |
| "Resistant hypertension is always fount to be accompanied with obstructive sleep apnea syndrome (OSAS)." | ( Li, NF; Liu, KJ; Wang, XL; Wang, YC; Yang, J; Yao, XG; Zhu, J; Zu, FY, 2010) |
| "Hypertension is associated with chronic vascular inflammation." | ( Bakker, EN; Brewster, LM; de Vos, J; Matlung, HL; Quax, PH; Seghers, L; Taherzadeh, Z; van Montfrans, G; VanBavel, E, 2010) |
| "Hypertension is particularly prevalent in patients aged ≥65 years, those with a body mass index ≥30 kg m(-2), Blacks and those with type II diabetes." | ( Chrysant, SG; Heyrman, R; Karki, S; Lee, J; Melino, M, 2010) |
| "Hypertension is very common in dialysis patients." | ( Ashkar, ZM, 2010) |
| "Arterial hypertension is an important risk factor for the development and progression of cardiovascular disease (CVD)." | ( Elisaf, MS; Florentin, M; Liberopoulos, EN; Mikhailidis, DP; Moutzouri, E, 2010) |
| "Hypertension is a common disease of the cardiovascular system and one of the main causes of mortality in the world." | ( Barciszewska, AM; Barciszewska, MZ; Gawronska, I; Jablecka, A; Nowak, S; Smolarek, I; Wyszko, E, 2010) |
| "Hypertension is a major risk factor for cardiovascular disease, which is the leading cause of mortality in women in developed countries." | ( Bush, CA; Gradman, AH; Keefe, DL; Weir, MR; Wright, M, 2010) |
| "Supine hypertension is a potentially serious complication that can appear in patients being treated for orthostatic hypotension with fludrocortisone or midodrine." | ( Castaño-García, B; Suárez-Moro, R, 2010) |
| "Hypertension is associated with endothelial dysfunction." | ( Szasz, T; Watts, SW, 2010) |
| "Arterial hypertension is a major cause of disease-related morbidity and mortality worldwide." | ( Büssemaker, E; Hausberg, M; Hillebrand, U; Oberleithner, H; Pavenstädt, H, 2010) |
| "Hypertension is a mechanism-based toxic effect of drugs that inhibit the vascular endothelial growth factor signaling pathway (VSP)." | ( Bakris, GL; Black, HR; Chen, HX; Durand, JB; Elliott, WJ; Ivy, SP; Leier, CV; Lindenfeld, J; Liu, G; Maitland, ML; Remick, SC; Steingart, R; Tang, WH, 2010) |
| "Hypertension is a powerful risk factor for cardiovascular disease and frequently occurs in conjunction with obesity and the metabolic syndrome." | ( Rizvi, AA, 2010) |
| "Obesity and hypertension are often comorbid, but the pathophysiologic mechanisms that link them are not fully understood." | ( Akalestos, A; Chrousos, GP; Kanaka-Gantenbein, C; Papassotiriou, I; Pervanidou, P; Sakka, S, 2010) |
| "Hypertension is the most common cardiovascular disease." | ( Cui, W; Huang, J; Long, C; Pan, Z; Wang, H; Zhang, Y, 2010) |
| "Hypertension is a major risk factor for cardiovascular disease and a leading cause of morbidity and mortality." | ( Ekman, M; Fragoulakis, V; Maniadakis, N; Papagiannopoulou, V; Yfantopoulos, J, 2011) |
| "Hypertension is most likely to occur in children <1 year of age during the continuous infusion, after they have received more than one bolus of dexmedetomidine." | ( Dinardo, JA; Fontaine, PJ; Mason, KP; Prescilla, R; Zgleszewski, S; Zurakowski, D, 2010) |
| "Diabetes and hypertension are closely associated with impaired endothelial function." | ( Muharis, SP; Murugan, D; Mustafa, MR; Top, AG, 2010) |
| "Arterial hypertension is one of the most important cardiovascular risk factors, featuring the unsatisfactory efficacy of current therapies." | ( Ast, J; Bogdanski, P; Chmara, E; Jablecka, A; Krauss, H; Smolarek, I, 2010) |
| "Hypertension is a major contributor to the development of renal failure, cardiovascular disease, and stroke." | ( Briones, AM; Touyz, RM, 2010) |
| "Hypertension is highly prevalent and is an important cardiovascular risk factor." | ( Ferreira, MG; Guimarães, LV; Martins, MS; Vianna, LA, 2010) |
| "Hypertension is the main clinic characteristic of ASH and asymmetric LV hypertrophy in patients with asymptomatic aortic stenosis independent of severity of aortic stenosis." | ( Cramariuc, D; Gerdts, E; Rieck, AE; Tuseth, N; Wachtell, K, 2010) |
| "Hypertension is a major cardiovascular risk factor, and treatment guidelines acknowledge the value not only of reducing elevated blood pressure (BP) to target levels (< 140/90 mmHg and < 130/80 mmHg in patients with diabetes or those at high cardiovascular risk) but also of doing this rapidly." | ( Barrios, V; Escobar, C, 2010) |
| "Obesity and hypertension are associated with left ventricular (LV) hypertrophy." | ( Cramariuc, D; Gerdts, E; Gohlke-Bärwolf, C; Lund, BP; Rieck, AE; Rossebø, AB, 2010) |
| "Vaccine against hypertension is an innovative treatment, injected every 4 - 6 months, to combat non-compliance." | ( Chen, Y; Do, TH; Nguyen, VT; Phisitkul, S, 2010) |
| "The pathogenesis of hypertension is multifactorial." | ( Chen, Y; Do, TH; Nguyen, VT; Phisitkul, S, 2010) |
| "Vaccines for hypertension are still in the early phase." | ( Chen, Y; Do, TH; Nguyen, VT; Phisitkul, S, 2010) |
| "Prehypertension is a highly frequent condition associated with an increased cardiovascular risk." | ( Bahlmann, FH; Doerries, C; Drexler, H; Giannotti, G; Horvàth, T; Jiang, H; Landmesser, U; Lüscher, TF; Manes, C; Marzilli, M; Mocharla, PS; Mueller, MF; Rudolph, KL; Sorrentino, SA; Steenken, N, 2010) |
| "Arterial hypertension is a multifactorial disease that is characterised by increased peripheral vascular resistance often accompanied by smooth muscle cell hypertrophy and proliferation." | ( Wirth, A, 2010) |
| "Hypertension is the most prevalent and important risk factor for cardiovascular and renal disease worldwide." | ( Ruddy, MC, 2010) |
| "Hypertension is associated with an increased risk of cognitive decline, which is generally regarded as a consequence of advanced cerebral atherosclerosis." | ( Gallinat, J; Joppke, M; Klär, AA; Schubert, F; Westhoff, TH; Wirth, C; Zidek, W, 2011) |
| "Hypertension is most important risk factor in coronary heart disease and cerebrovascular accidents." | ( Arif, AF; Joshi, C; Kadam, GG, 2009) |
| "Hypertension is a significant factor, increasing the risk of death by 3-5 times, both in women and men." | ( Banach, M; Barylski, M; Irzmański, R; Kowalski, J; Pawlicki, L; Serwa-Stepień, E, 2005) |
| "Systolic hypertension is very common in the elderly and is strongly associated with the risk of cardiovascular and cerebrovascular events." | ( Ambrosioni, E; Bombelli, M; Cerasola, G; Cipollone, F; Ferri, C; Grazioli, I; Leprotti, C; Mancia, G; Melzi, G; Mugellini, A; Mulè, G; Palasciano, G; Salvetti, A; Trimarco, B, 2010) |
| "Intra-abdominal hypertension is common in critically ill patients and is associated with increased morbidity and mortality." | ( Hockings, LE; Musk, GC; Noffsinger, B; Regli, A; Roberts, B; Singh, B; van Heerden, PV, 2010) |
| "Arterial hypertension is associated with increased levels of reactive oxygen species, which may scavenge endothelium-derived NO and thereby diminish its vasorelaxant effects." | ( Armitage, ME; Beuerlein, K; Janowitz, D; Kumar, AH; Neff, C; Schmidt, HH; Shah, AM; Taye, A; Wind, S; Wingler, K, 2010) |
| "Resistant hypertension is defined as failure to lower blood pressure to target when a patient adheres to the maximum tolerated doses of three antihypertensive drugs including a diuretic." | ( Enseleit, F; Lüscher, TF; Ruschitzka, F, 2010) |
| "Hypertension is associated with greater decline in cognition with age, but whether treatment of hypertension affects this is uncertain." | ( Beardmore, R; Beckett, N; Bulpitt, C; Mitnitski, A; Mt-Isa, S; Peña-Miller, R; Peters, R; Rockwood, K, 2010) |
| "Hypertension is an underlying risk factor for cardiovascular disease." | ( Camacho Londoño, JE; Flockerzi, V; Freichel, M; Herijgers, P; Hummel, B; Kees, F; Mathar, I; Meissner, M; Nilius, B; Schweda, F; Uhl, S; van den Bergh, A; Van der Mieren, G; Vennekens, R; Voets, T, 2010) |
| "Hypertension is the most important effector of MPR in subjects without myocardial ischemia." | ( Dohi, K; Ishida, M; Ito, M; Kitagawa, K; Kurita, T; Nagata, M; Nakajima, H; Nakamura, M; Onishi, K; Sakuma, H, 2010) |
| "Hypertension is associated with an increased risk of stroke, myocardial infarction and congestive heart failure." | ( Kandler, MR; Mah, GT; Stabler, SN; Tejani, AM, 2010) |
| "Since hypertension is a common toxicity of sorafenib, clinicians should be aware of this possible interaction." | ( Billemont, B; Blanchet, B; Coriat, R; Dauphin, A; Faivre, L; Goldwasser, F; Gomo, C; Mir, O; Ropert, S; Tod, M, 2011) |
| "Hypertension is frequently seen in autosomal dominant polycystic kidney disease (ADPKD), and it has a negative effect on renal progression." | ( Kaynar, K; Kiriş, A; Koşucu, P; Orem, C; Ozkan, G; Ulusoy, S, 2010) |
| "Hypertension is one of the common chronic cardiovascular diseases that lead to heart attacks, strokes, chronic heart failure, and chronic renal failure." | ( Akpek, M; Ardic, I; Calapkorur, B; Dogan, A; Dogdu, O; Kalay, N; Kaya, MG; Oguzhan, A; Ozdogru, I; Ozdogru, M; Yarlioglues, M, 2010) |
| "Hypertension is a well-recognized complication of autosomal recessive polycystic kidney disease (ARPKD)." | ( Dell, KM; Goto, M; Hoxha, N; Osman, R, 2010) |
| "Hypertension is a major contributor to the cardiovascular morbidity and mortality in industrialized countries." | ( Idris, MZ; Midha, T; Saran, RK; Singh, SK; Srivastav, AK, 2009) |
| "Hypertension is the leading cause of cardiovascular diseases, and angiotensin II is one of the major components of the mechanisms that contribute to the development of hypertension." | ( Das, K; Estes, AM; Fang, XR; Farjana, N; Gonzalez, FJ; Jennings, BL; Malik, KU; Sahan-Firat, S, 2010) |
| "Hypertension is one of the most important risk factors and causes of cardiovascular disease (CVD)." | ( Bellocci, F; d'Orazio, N; Riccioni, G; Vitulano, N; Zanasi, A, 2010) |
| "Hypertension is a common toxicity of anti-VEGF agents, but its optimal treatment remains to define." | ( Billemont, B; Blanchet, B; Cabanes, L; Camps, S; Coriat, R; Goldwasser, F; Knebelmann, B; Mir, O; Ropert, S, 2012) |
| "Hypertension is the most important risk factor for cardiovascular mortality." | ( Barnett, AG; Guo, Y; Li, S; Pan, X; Tong, S; Yu, W; Zhang, Y, 2010) |
| "Hypertension is emerging as one of the most common adverse effects of therapy with angiogenesis inhibitors." | ( Afonso-Afonso, FJ; Antón-Aparicio, LM; Aparicio-Gallego, G; Campos-Balea, B; Fernández-Calvo, O; Fírvida-Pérez, JL; Lázaro-Quintela, M; León-Mateos, L; Ramos-Vázquez, M; Vázquez-Estévez, S, 2011) |
| "Hypertension is associated with an increased risk of thrombosis that appears to involve an interaction between the renin-angiotensin system and hemostasis." | ( Almeida-Paula, LD; Granger, DN; Harding, JW; Russell, J; Senchenkova, EY, 2010) |
| "Hypertension is a serious risk factor for cardiovascular disease, and the angiotensinogen (AGT) gene locus is associated with human essential hypertension." | ( Chauhan, CK; Fiering, SN; Jain, S; Kumar, A; Mopidevi, B; Pandey, VG; Tillinger, A; Warming, S, 2010) |
| "Hypertension is a risk factor for myocardial infarction (MI), stroke, and heart failure and precedes heart failure in 91% of cases." | ( Black, HR; Greenberg, BH; Weber, MA, 2010) |
| "Childhood hypertension is an established predictor of adult hypertension and organ damage, an underestimated problem in developing countries." | ( Aiello, A; Antolini, L; Doneda, A; Gallieni, M; Genovesi, S; Giussani, M; Mandal, SK; Stella, A; Tucci, B; Valsecchi, MG, 2011) |
| "Hypertension is a widely prevalent condition of elevated blood pressure (BP) and is the leading risk factor for the development of cardiovascular disease (CVD)." | ( Van Bortel, LM, 2010) |
| "Hypertension is a known risk factor for cardiovascular events and mortality." | ( Wilford Germino, F, 2010) |
| "Acute and severe hypertension is common, especially in patients with renal dysfunction (RD)." | ( Dunbar, L; Ebrahimi, R; Frank Peacock, W; Pollack, CV; Varon, J, 2011) |
| "Hypertension is one of the most important risk factor and cause of cardiovascular diseases (CVD)." | ( Riccioni, G, 2011) |
| "Hypertension is the most common comorbidity and major risk factor in patients with erectile dysfunction." | ( Choi, YH; Kim, TK; Lee, BY; Lee, MG; Lee, YS; Ryu, KH; Yoon, IS, 2011) |
| "Hypertension is an increasingly prevalent cardiovascular risk factor associated with high rates of morbidity and mortality." | ( Ram, CV, 2011) |
| "Hypertension is one of cardiac hypertrophy factors, SBP correlate better with LVW/ BW than DBP." | ( Li, HY; Liu, ZQ; Qi, L; Tong, CQ, 2003) |
| "Hypertension is well known to increase atrial fibrillation (AF) and the development of AF is associated with atrial chamber remodeling." | ( Aizawa, Y; Chinushi, M; Ding, L; Hanawa, H; Hoyano, M; Ito, M; Kimura, S; Kodama, M; Obata, H; Tomita, M, 2011) |
| "Hypertension is a typical modern lifestyle-related disease that is closely associated with the development of cardiovascular disorders." | ( Imai, Y; Manabe, I; Nagai, R; Nakajima, A; Ohba, Y; Osawa, T; Takaoka, A; Taniguchi, T; Tsushima, K; Yanai, H, 2011) |
| "Induced hypertension is an established therapy to treat cerebral vasospasm (CVS) following subarachnoid hemorrhage (SAH) to prevent delayed ischemic deficits." | ( Beck, J; Berkefeld, J; Güresir, E; Platz, J; Raabe, A; Seifert, V; Vatter, H, 2011) |
| "Essential hypertension is considered a serious health problem and diet can play an important role in its prevention and treatment." | ( Carrón, R; Contreras, Mdel M; Kassan, M; Montero, MJ; Recio, I; Sánchez, D; Sevilla, MÁ, 2011) |
| "Essential hypertension is a complex multifactorial disease caused by interactions between genetic and environmental factors." | ( Gopi Chand, M; Kumar, S; Lakkakula, BV; Rao, RS; Rao, VR; Srinath, J, 2011) |
| "Essential hypertension is a major risk factor for cardiovascular, cerebrovascular, and renal diseases." | ( Cai, J; Yang, X; Yang, Y; Zhang, M, 2011) |
| "Menopause and hypertension are both important risk factors for liver damage and several other circulatory abnormalities." | ( Albayrak, F; Altunkaynak, ZB; Bayram, E; Beyzagül, P; Dursun, H; Halici, Z; Keleş, NO; Okçu, N; Süleyman, H; Ünal, B; Uyanik, A, 2010) |
| "Hypertension is frequent among patients with chronic renal failure and sometimes it is necessary to use agents, like minoxidil." | ( Kumar, S; Mukherjee, JT; Nautiyal, A; Schick, EC; Wong, T, 2011) |
| "Arterial hypertension is frequently observed in renal transplant recipients." | ( Cucchiari, D; Graziani, G; Ponticelli, C, 2011) |
| "Arterial hypertension is commonly associated with hyperuricemia." | ( Kostka-Jeziorny, K; Tykarski, A; Uruski, P, 2011) |
| "Hypertension is associated with vascular changes characterised by remodelling, endothelial dysfunction and hyperreactivity." | ( Burger, D; Montezano, A; Nishigaki, N; Savoia, C; Touyz, RM, 2011) |
| "Sodium-sensitive hypertension is caused by renal tubular dysfunction, leading to increased retention of sodium and water." | ( Bianchi, G; Ferrari, P; Procino, G; Romano, F; Svelto, M; Torielli, L; Valenti, G, 2011) |
| "Hypertension is a major risk factor of Alzheimer's disease (AD); however, controlled studies on the effect of antihypertensive treatment on the risk of dementia are inconclusive." | ( Bergmann, A; Blennow, K; Buerger, K; Ernst, A; Hampel, H; Hansson, O; Hartmann, O; Minthon, L; Moeller, HJ; Rujescu, D; Schneider, P; Teipel, S; Uspenskaya, O; Zetterberg, H, 2011) |
| "Hypertension is a major risk factor for cardiovascular, renal and stroke complications." | ( Chrysant, SG, 2011) |
| "Hypertension is one of the most common human diseases worldwide, and extensive research efforts are focused upon the identification and utilizing of novel therapeutic drug targets." | ( Gang, GT; Hwang, JH; Kim, DH; Kim, YH; Kwak, TH; Lee, CH; Lee, IK; Noh, JR; Shong, M; Son, HY, 2011) |
| "Furthermore, hypertension is one of the major risk factors for development and progression of diabetic retinopathy, and control of blood pressure has been shown in large clinical trials to prevent visual loss from diabetic retinopathy." | ( Bhargava, M; Ikram, MK; Wong, TY, 2012) |
| "Hypertension is a major risk factor for cardiovascular disease." | ( Reckelhoff, JF; Yanes, LL, 2011) |
| "Systemic arterial hypertension is a highly prevalent cardiovascular risk factor that causes significant morbidity and mortality, and is becoming an increasingly common health problem because of the increasing longevity and prevalence of predisposing factors such as sedentary lifestyle, obesity and nutritional habits." | ( Gori, T; Münzel, T; Schulz, E, 2011) |
| "Essential hypertension is a multifactorial disorder and a risk factor for renal failure and cardiovascular disease." | ( Ichikawa, K; Kato, T; Kawata, S; Konta, T; Kubota, I; Kudo, K; Mashima, Y; Shibata, Y; Suzuki, K; Takasaki, S; Watanabe, T, 2011) |
| "Hypertension is a major risk factor for cardiovascular disease, but control of hypertension remains inadequate, often because of poor patient adherence to prescribed medical regimens that are viewed as poorly tolerated and expensive." | ( Black, HR; Slim, HB; Thompson, PD, 2011) |
| "Treatment of hypertension is fundamental for the prevention of cardiovascular events and mortality." | ( Ghiadoni, L, 2011) |
| "Essential hypertension is a multifactorial disorder which belongs to the main risk factors responsible for renal and cardiovascular complications." | ( Kuneš, J; Pintérová, M; Zicha, J, 2011) |
| "Hypertension is strongly associated with cardio/cerebrovascular diseases, e." | ( Blacher, J; Jankowski, P; Safar, ME, 2011) |
| "Essential hypertension is the leading risk factor for mortality worldwide, accountable for 13% of deaths globally." | ( Andrews, KL; Chin-Dusting, JP; Michell, DL, 2011) |
| "In humans, hypertension is considered a state of oxidative stress that can contribute to the development of atherosclerosis and other hypertension-induced organ damages." | ( Abe, S; Ali, A; Rao, MR; Sambandam, G; Sankar, D; Saraswathi, R; Uehara, Y, 2011) |
| "Prehypertension is associated with impaired NO-mediated endothelium-dependent vasodilation." | ( DeSouza, CA; Greiner, JJ; Stauffer, BL; Weil, BR, 2011) |
| "Hypertension is related to abnormalities in autonomic nervous system (ANS) function, with increased sympathetic output and decreased parasympathetic tone." | ( Edwards, KM; Mills, PJ; Sadja, J; Wilson, KL; Ziegler, MG, 2011) |
| "Hypertension is an important risk factor for cardiovascular complications and the need to treat this condition has been well established." | ( de Leeuw, PW, 2011) |
| "Hypertension is a major risk factor for the development and progression of chronic kidney disease (CKD)." | ( Acelajado, MC; Calhoun, DA; Cartmill, FR; Cofield, SS; Dell'Italia, LJ; Dudenbostel, T; Oparil, S; Pisoni, R, 2012) |
| "Hypertension is difficult to treat in patients with type 2 diabetes mellitus (T2DM) or obesity." | ( Neutel, JM, 2011) |
| "Hypertension is common in the elderly, and its prevalence increases with aging." | ( Cohen, DL; Townsend, RR, 2011) |
| "While hypertension is associated with a hyperadrenergic state during wakefulness, the effect of hypertension on plasma-catecholamine levels during sleep is not yet known." | ( Born, J; Dodt, C; Mölle, M; Rasch, B; Sayk, F, 2011) |
| "Hypertension is one of the leading causes of mortality and morbidity in the world, which is influenced by environmental and genetic factors." | ( Atik, S; Demirel, Y; Dogan, S; Ozdemir, O; Silan, C; Silan, F; Uludag, A, 2011) |
| "Hypertension is one of the main drivers of the heart failure (HF) epidemic." | ( Baugh, JA; Collier, P; Jan, A; Ledwidge, MT; Mak, G; Martos, R; McDonald, KM; Phelan, D; Voon, V; Watson, CJ, 2011) |
| "Hypertension is associated with the development of atrial fibrillation; however, the electrophysiological consequences of this condition remain poorly understood." | ( Bao, L; Coetzee, WA; Fishman, GI; Kefalogianni, E; Lader, JM; Maass, K; Morley, GE; Qu, J; Vasquez, C, 2011) |
| "Hypertension is the most common cardiovascular disease worldwide and is a major cause of morbidity and mortality." | ( Adebiyi, AA; Akinosun, OM; Falase, AO; Nwafor, CE, 2011) |
| "Hypertension is the most important associated factor contributing to development of nephropathy in these patients." | ( Agarwal, N; Jain, PK; Khare, R; Sengar, NS, 2011) |
| "Hypertension is a leading contributor to cardiovascular mortality worldwide." | ( Ando, K; Ayuzawa, N; Fujita, T; Ishikawa, A; Ishizawa, K; Kawarazaki, H; Kawarazaki, W; Miyoshi, J; Mu, S; Muraoka, K; Nagase, M; Shibata, S; Shimosawa, T; Takai, Y; Takeuchi, M; Yoshida, S, 2011) |
| "Hypertension is a disorder affecting millions worldwide, and is a leading cause of death and debilitation in the United States." | ( Labazi, H; Tostes, RC; Webb, RC; Wynne, BM, 2012) |
| "Hypertension is a common co-morbidity in patients with type 2 diabetes mellitus, and well tolerated, effective therapies are needed to achieve guideline-recommended blood pressure (BP) goals in these patients." | ( Kereiakes, DJ; Neutel, JM, 2011) |
| "Essential hypertension is associated with mitochondrial dysfunction." | ( Hong, KW; Jeong, SY; Jin, HS; Kim, BY; Laan, M; Oh, B; Org, E; Sober, S, 2011) |
| "Hypertension is a well established risk factor for cardiovascular diseases such as stroke and is the leading cause of chronic kidney failure." | ( Breyer, RM; Swan, CE, 2011) |
| "Hypertension is prevalent in the United States and remains uncontrolled." | ( Crabbe, A; Delkhah, Y; Jones, J; Leonard, D; Nesbitt, S; Oliver, S, 2011) |
| "Hypertension is more prevalent among HIV-infected individuals than in the general population and contributes to increased cardiovascular risk." | ( De Caterina, R; Di Iorio, A; Falasca, K; Mancino, P; Ucciferri, C; Vecchiet, J, 2011) |
| "Hypertension is associated with the imbalance of vasoconstrictor and vasodilator systems." | ( Behuliak, M; Kuneš, J; Pintérová, M; Zicha, J, 2011) |
| "Hypertension is associated with marked alterations in vascular sphingolipid biology such as elevated ceramide levels and signaling, that contribute to increased vascular tone." | ( Alewijnse, AE; Chalfant, CE; De Mey, JG; Debets, JJ; Eijkel, GB; Heeren, RM; Janssen, BJ; MacAleese, L; Peters, SL; Spijkers, LJ; Stroes, ES; van den Akker, RF; van den Born, BJ; Wijesinghe, DS, 2011) |
| "Hypertension is closely associated with progressive kidney dysfunction, manifested as glomerulosclerosis, interstitial fibrosis, proteinuria, and eventually declining glomerular filtration." | ( Nordquist, L; Palm, F, 2011) |
| "Hypertension is a risk factor for osteoporosis." | ( Guan, XX; Li, JY; Zhou, Y, 2011) |
| "Hypertension is a well established risk factor for the development of cardiovascular diseases and increased mortality." | ( Cirule, H; Dambrova, M; Grinberga, S; Kalvinsh, I; Kuka, J; Liepinsh, E; Svalbe, B; Vilskersts, R, 2011) |
| "Hypertension is one of the leading causes of disability or death due to stroke, heart attack and kidney failure." | ( Dornas, WC; Silva, ME, 2011) |
| "Hypertension is also related to poor performance in tests that assess cognitive functions." | ( De Castro, MS; Ferreira, MB; Fuchs, FD; Jacobs, Ú, 2011) |
| "Hypertension is the leading cause of cardiovascular disease worldwide." | ( Chang, KH; Chen, CJ; Chen, JW; Chou, KM; Huang, YL; Li, WF; Tsai, LY; Wang, SL, 2011) |
| "Hypertension is a major risk factor for coronary heart disease, stroke, heart failure and renal disease." | ( Khawaja, Z; Wilcox, CS, 2011) |
| "Hypertension is one of the most common cardiovascular diseases." | ( Dralova, OV; Ermolaeva, AS; Maksimov, ML, 2011) |
| "Hypertension is characterized by a sustained increase in vasoconstriction and attenuated vasodilation in the face of elevated mechanical stress in the blood vessel wall." | ( Chao, JT; Davis, MJ, 2011) |
| "Systemic hypertension is one of the most common preexisting conditions." | ( Bentley, RT; March, PA, 2011) |
| "Resistant hypertension is a well recognized clinical entity, which has been inadequately researched to date." | ( Chang, CL; Dahlöf, B; Gupta, AK; Nasothimiou, EG; Poulter, NR; Sever, PS, 2011) |
| "Hypertension is an important public health problem in India." | ( Agrawal, A; Dey, S; Gupta, R; Guptha, S; Kamalamma, N; Menon, VU; Misra, A; Misra, P; Pandey, RM; Rao, S; Revathi, K; Sharma, V; Vasantha Devi, KP; Vikram, NK, 2012) |
| "Hypertension is the main risk factor for left ventricular hypertrophy and development of diastolic heart failure." | ( Biala, A; Finckenberg, P; Korpi, A; Levijoki, J; Loytainen, M; Martonen, E; Mervaala, E, 2011) |
| "Hypertension is associated with impaired glucose tolerance and insulin resistance." | ( Daida, H; Fukao, K; Hiki, M; Hirose, K; Kiyanagi, T; Kume, A; Kurata, T; Matsumori, R; Miyazaki, T; Ohsaka, H; Shimada, K, 2011) |
| "Essential hypertension is a proinflammatory, proconstrictor disease coinciding with endothelial dysfunction and inward vessel remodeling." | ( Berkowitz, DE; Bruning, RS; Holowatz, LA; Santhanam, L; Smith, CJ; Stanhewicz, A, 2011) |
| "Hypertension is a common adverse effect that is usually easily managed." | ( Gupta, R; Maitland, ML, 2011) |
| "Hypertension is a risk factor for arterial thrombosis." | ( Clemetson, KJ; Gebhard, S; Gesell-Salazar, M; Greinacher, A; Hammer, E; Kuttler, B; Peters, B; Peters, J; Rettig, R; Scharf, C; Steil, L; Völker, U, 2011) |
| "ANG II-dependent hypertension is associated with enhanced protein degradation in platelets." | ( Clemetson, KJ; Gebhard, S; Gesell-Salazar, M; Greinacher, A; Hammer, E; Kuttler, B; Peters, B; Peters, J; Rettig, R; Scharf, C; Steil, L; Völker, U, 2011) |
| "Hypertension is a major public health problem with prevalence ranging 22-30% in urban India." | ( Gupte, MD; Kaur, P; Radhakrishnan, E; Rajasekar, D; Rao, SR, 2012) |
| "Hypertension is an emerging challenge in rural India." | ( Gupte, MD; Kaur, P; Radhakrishnan, E; Rajasekar, D; Rao, SR, 2012) |
| "Hypokalemic hypertension is a common condition leading to the diagnosis of secondary hypertension." | ( Chow, KM; Li, PK; Ma, RC; Szeto, CC, 2012) |
| "Hypertension is the most important modifiable risk factor for intracerebral hemorrhage (ICH), but blood pressure (BP) management during the acute phase of ICH is still controversial." | ( Asil, T; Balci, K; Celik, Y; Ir, N; Tekinaslan, I; Unlu, E; Utku, U, 2012) |
| "Hypertension is an important cardiovascular risk factor for the development of atrial fibrillation (AF)." | ( Acar, G; Akçay, A; Altun, B; Kaya, H; Köroğlu, S; Sökmen, A, 2011) |
| "Hypertension is an important cardiovascular risk factor that influences patient survival." | ( Hryniewiecka, E; Paczek, L; Zegarska, J, 2011) |
| "Hypertension is a key risk factor in the progression of cardiovascular disease (CVD)." | ( Gao, P; Hu, C; Kong, H; Li, Y; Peng, S; Qu, F; Xu, G; Yu, Z, 2011) |
| "Hypertension is associated with an increased risk of diastolic dysfunction." | ( Fukuda, S; Ishii, K; Ito, H; Iwakura, K; Kasayuki, N; Kihara, H; Nakamura, F; Shimada, K; Yoshikawa, J, 2012) |
| "Hypertension is one of the major risk factor that underlie a wide range of cardiovascular irregularities which causes functional and metabolic alterations in vascular system and major organs." | ( Balamurugan, E; Manivannan, J; Raja, B; Saravanakumar, M; Silambarasan, T; Sivasubramanian, J, 2012) |
| "Secondary hypertension is responsible for less than 10% of cases of hypertension." | ( Ossareh, S; Shadpour, P; Shooshtarizadeh, T, 2011) |
| "Hypertension is associated with an increased risk of stroke, myocardial infarction and congestive heart failure." | ( Kandler, MR; Mah, GT; Salzwedel, DM; Stabler, SN; Tejani, AM, 2011) |
| "Essential hypertension is a multifactorial disease in which genetic and environmental factors play an important role." | ( Bhatia, J; Meena, PC; Narang, R; Saluja, D; Srivastava, K; Sundriyal, R, 2012) |
| "Hypertension is considered a low-grade inflammatory condition, and understanding the role of transcription factors in guiding this response is pertinent." | ( Agarwal, D; Cardinale, JP; Francis, J; Mariappan, N; Sriramula, S, 2012) |
| "Hypertension is common in hemodialysis patients and contributes to this population's high risk for cardiovascular morbidity and mortality." | ( Inrig, JK; Toto, R; Van Buren, PN, 2012) |
| "Intradialytic hypertension is associated with increased morbidity and mortality, impaired endothelial cell function, and higher overall blood pressure burden." | ( Inrig, JK; Toto, R; Van Buren, PN, 2012) |
| "Uncontrolled hypertension is common among older people in developing countries, and may rise further during the demographic and health transitions." | ( Acosta, D; Ebrahim, S; Ferri, CP; Gonzalez-Viruet, M; Guerra, M; Huang, Y; Jacob, KS; Jimenez-Velazquez, IZ; Jotheeswaran, AT; Liu, Z; Prince, MJ; Rodriguez, JL; Salas, A; Sosa, AL; Williams, JD, 2012) |
| "Hypertension is linked to disturbed total-body sodium (Na(+)) regulation; however, measuring Na(+) disposition in the body is difficult." | ( Cavallaro, A; Dahlmann, A; Eckardt, KU; Horbach, T; Kopp, C; Linz, P; Luft, FC; Müller, DN; Neininger, M; Niendorf, T; Renz, W; Santoro, D; Schmieder, RE; Schöfl, C; Titze, J; Uder, M; Wachsmuth, L, 2012) |
| "Hypertension is associated with end-organ damage (EOD)." | ( Babuvinish, D; Grootveld, M; Meenakshisundaram, R; Rajendiran, C; Thirumalaikolundusubramanian, P, 2012) |
| "1." | ( Cowely, AW; Ito, S; Mori, T; Ogawa, S, 2012) |
| "Hypertension is a major health problem and is usually associated with common conditions such as obesity, which contribute to clinical cardiac dysfunction." | ( Borgiel-Marek, H; Karcz, K; Karcz-Socha, I; Zembala, M; Zwirska-Korczala, K, 2011) |
| "Hypertension is a multifactorial disease in which the interplay of genetic and environmental factors that maintain blood pressure stable throughout life is altered." | ( Fava, C; Melander, O; Minuz, P; Ricci, M, 2012) |
| "Hypertension is a prerequisite for advanced diabetic nephropathy in humans, so its rarity in typical rodent models may partly explain their resistance to nephropathy." | ( Bailey, MA; Bellamy, CO; Conway, BR; Dunbar, DR; Hughes, J; Manning, JR; Mullins, JJ; Rennie, J, 2012) |
| "Hypertension is a common cardiovascular disease and can induce many complications, such as stroke and coronary heart disease." | ( Bi, XY; Hu, H; Yu, XJ; Zang, WJ; Zhang, HL; Zhao, M, 2011) |
| "Hypertension is associated with endothelial dysfunction and activated Rho-associated kinases (ROCKs)." | ( Chayama, K; Fujii, Y; Fujimura, N; Hata, T; Hidaka, T; Higashi, Y; Idei, N; Iwamoto, Y; Kato, H; Kihara, Y; Liao, JK; Maruhashi, T; Mikami, S; Noma, K; Soga, J, 2012) |
| "Induced hypertension is currently recommended for treating suspected DCI, whereas hemodilution and hypervolemia are not." | ( Keller, E; Mishima, K; Muroi, C; Seule, M, 2012) |
| "Hypertension is one of the important clinical problems of diabetic cardiovascular disease." | ( Abdollahzadeh, N; Heshmatian, B; Ilkhanizadeh, B; Khadem Ansari, MH; Noruzi, L; Saboory, E; Shirpoor, A, 2012) |
| "Hypertension is a leading risk factor for cardiovascular disease (CVD) and stroke." | ( Horigan, G; McNulty, H; Scott, JM; Strain, JJ; Ward, M; Wilson, CP, 2011) |
| "Hypertension is a major issue in public health, and the financial costs associated with hypertension continue to increase." | ( Berwanger, O; Mion Júnior, D; Ortega, KC; Silva, GV; Tsuji, RL, 2012) |
| "The MR-associated hypertension is classified into two subtypes, that with elevated plasma aldosterone levels and that with normal plasma aldosterone levels." | ( Itoh, H; Shibata, H, 2012) |
| "We confirmed that hypertension is an important health challenge for the mining industry in South Africa." | ( Maepe, LM; Outhoff, K, 2011) |
| "Currently, if hypertension is present in 20% of the population, PA will account for 2%; of these PA patients only 1% are ever screened, let alone diagnosed and treated, and the remaining 99% suboptimally treated, if at all." | ( Funder, JW, 2012) |
| "Salt-sensitive hypertension is a characteristic of the metabolic syndrome." | ( Araki, H; Araki, S; Chin-Kanasaki, M; Deji, N; Haneda, M; Isshiki, K; Kashiwagi, A; Koya, D; Kume, S; Maegawa, H; Nishiyama, A; Tanaka, Y; Uzu, T, 2012) |
| "Hypertension is associated with dyslipidemia, which is a significant risk factor for cardiovascular complications." | ( Raja, B; Saravanakumar, M, 2012) |
| "Morning hypertension is an independent risk factor for cardiovascular diseases, particularly stroke." | ( Dobashi, H; Hosomi, N; Kohno, M; Masugata, H; Matsumoto, M; Miki, T; Murao, K; Nishiyama, A; Sueda, Y; Ueno, M, 2012) |
| "Hypertension is a major link between hyperhomocysteinemia and CAD occurrence." | ( Abchee, AB; Badro, DA; Cazier, JB; Chammas, E; Douaihy, B; el Bayeh, H; Gauguier, D; Ghassibe-Sabbagh, M; Haber, M; Hager, J; Kamatani, Y; Kibbani, S; Milane, A; Nemr, R; Othman, R; Platt, DE; Salloum, AK; Shasha, N; Stewart, K; Youhanna, S; Zalloua, PA, 2012) |
| "Hypertension is a major risk factor for cardiovascular disease in women and men, but cardiovascular disease is the leading cause of death in women." | ( Lima, R; Reckelhoff, JF; Wofford, M, 2012) |
| "Hypertension is one of the main risk factors of cardiovascular diseases." | ( Amoussou, M; Djrolo, F; Gbary, AR; Houehanou, YC; Houinato, DS; Kpozehouen, A; Salamon, R; Segnon-Agueh, J, 2012) |
| "DOCA-salt-induced hypertension is associated with H(4)B oxidation and uncoupling of eNOS." | ( Blair, J; Cai, H; Harrison, DG; Laude, KM; McCann, LA; Oak, JH; Wang, T; Youn, JY, 2012) |
| "Hypertension is common among renal transplant recipients (RTR) and a risk factor for graft failure and mortality." | ( Bakker, SJ; Brink, EJ; Gans, RO; Geleijnse, JM; Homan van der Heide, JJ; Navis, G; van Baak, MA; van den Berg, E, 2012) |
| "Hypertension is the most prevalent and potentially modifiable risk factor for atrial fibrillation (AF)." | ( Derosa, G; Fogari, R; Maffioli, P; Mugellini, A; Perrone, T; Preti, P; Zoppi, A, 2012) |
| "Obesity and hypertension are associated with an adverse metabolic profile and systemic low-grade inflammation." | ( Chen, J; He, H; Li, Y; Liu, D; Ni, Y; Pletcher, MJ; Yan, Z; Zhao, Z; Zhong, J; Zhu, Z, 2012) |
| "Untreated essential hypertension is associated with significantly reduced post-operative morphine requirement and pain intensity, suggesting hypertension-associated hypoalgesia." | ( Cai, XJ; Li, ZY; Luo, F, 2013) |
| "Hypertension is a common comorbidity in patients with heart failure and may contribute to development and course of disease, but the importance of a history of hypertension in patients with prevalent heart failure remains uncertain." | ( Akkan, D; Andersson, C; Gislason, GH; Hassager, C; Kjaergaard, J; Køber, L; Møller, JE; Torp-Pedersen, C; Weeke, P, 2012) |
| "Hypertension is a powerful risk factor for cardiovascular disease and frequently occurs in conjunction with obesity." | ( Bogdański, P; Cymerys, M; Dytfeld, J; Jabłecka, A; Korczowska, I; Pupek-Musialik, D; Łącki, J, 2012) |
| "Hypertension is one of the main factors causing cardiovascular diseases." | ( Ho, PY; Peng, HC; Yang, HY; Yang, SC; Yang, YC, 2013) |
| "Hypertension is a major risk factor for vascular disease, yet blood pressure (BP) control is unsatisfactory low, partly due to side-effects." | ( Manhem, K; Mannheimer, C; Mourtzinis, G; Silverdal, J; Stener-Victorin, E, 2012) |
| "Age and hypertension are two major determinants of arterial stiffness, as well as endothelial dysfunction." | ( Clavreul, N; Isabelle, M; Ragonnet, C; Sansilvestri-Morel, P; Simonet, S; Vayssettes-Courchay, C; Verbeuren, TJ, 2012) |
| "Sex differences in hypertension are not well known." | ( Cao, XL; Htet Aung, LH; Li, M; Liu, WY; Long, XJ; Miao, L; Pan, SL; Wu, DF; Wu, JZ; Yin, RX; Zhang, L, 2012) |
| "Control of hypertension is the most important public health measure." | ( Munshi, SK; Sprigg, N; Thanvi, BR, 2012) |
| "Hypertension is one of the most prevalent disorders and the largest contributor to global mortality." | ( Fujimoto, A; Kuwahara, K; Nakagawa, Y; Ueshima, K; Yasuno, S, 2012) |
| "Sorafenib-induced hypertension is a positive predictive factor in mRCC patients treated with sorafenib, especially in patients with a history of hypertension." | ( Filipiak, KJ; Nurzyński, P; Opolski, G; Szczylik, C; Szmit, S; Waśko-Grabowska, A; Zaborowska, M; Żołnierek, J, 2012) |
| "Essential hypertension is one of the main risk factors for the development of coronary artery disease (CAD)." | ( Alexánderson, E; Alexánderson, G; Cabral, MA; Iñarra, F; Jácome, R; Jiménez-Santos, M; Meave, A; Ochoa, JM; Ricalde, A; Romero, E, 2012) |
| "Essential hypertension is characterized by both increased oxidative stress and sympathetic traffic." | ( Bruno, RM; Daghini, E; Emdin, M; Ghiadoni, L; Passino, C; Rugani, I; Sudano, I; Taddei, S; Varanini, M, 2012) |
| "Hypertension is a common side effect of VEGF inhibitors used in cancer medicine." | ( Bagby, SP; Belcik, JT; Bullens, S; Bunting, S; Kaufmann, BA; Kolumam, G; Kowalski, J; Lindner, JR; Morgan, TK; Oyer, JA; Qi, Y; Xie, A, 2012) |
| "Arterial hypertension is characterised by increased oxidative stress and inflammation, which are associated with further cardiovascular risk." | ( Eha, J; Kals, J; Kampus, P; Kullisaar, T; Serg, M; Zagura, M; Zilmer, K; Zilmer, M, 2012) |
| "Hypertension is a major risk factor for coronary artery disease, stroke, and kidney failure." | ( Byun, HS; Li, DP; Li, L; Pan, HL; Ye, ZY, 2012) |
| "Hypertension is characterized by left ventricular (LV) hypertrophy (LVH)." | ( Baid, S; Garcia, AG; Heo, J; Murthy, NR; Ouchi, N; Sam, F; Wilson, RM, 2012) |
| "Hypertension is a dose-limiting toxicity for VEGF inhibitors." | ( Bazinet, L; Birsner, AE; Dallabrida, SM; Durand, E; Folkman, JM; Ikeda, S; Ismail, NS; Javaherian, K; Kulke, MH; Pu, WT; Rupnick, M; Sohn, R; Sunshine, SB; Zurakowski, D, 2012) |
| "Hypertension is a prevalent condition that is closely associated with chronic complications in patients with diabetes." | ( Chen, JF; Hung, YJ; Lee, IT; Lee, WJ; Sheu, WH; Wang, CY, 2012) |
| "Hypertension is a toxicity of antiangiogenic therapies and a possible biomarker that identifies patients with superior cancer outcomes." | ( de Jesus-Gonzalez, N; Demetri, G; George, S; Heinrich, MC; Humphreys, BD; Penchev, R; Robinson, E; Tap, W; von Mehren, M; Wang, Q, 2012) |
| "Hypertension is associated with fibrinolysis abnormality." | ( Bektaş, O; Karahan, SC; Kaynar, K; Menteşe, A; Ozkan, G; Sönmez, M; Ulusoy, S, 2013) |
| "Masked hypertension is a common feature in type 2 diabetic patients being treated for hypertension." | ( Araki, H; Araki, S; Isshiki, K; Kashiwagi, A; Kawai, H; Kume, S; Maegawa, H; Nakao, K; Ugi, S; Uzu, T, 2012) |
| "Hypertension is an important public health problem and the major causes of cardiovascular morbidity and mortality among aged and elderly population in India." | ( Kaur, M, 2012) |
| "The prevalence of hypertension is growing at an alarming rate." | ( Broncel, M; Duchnowicz, P; Jackowska, P; Koter-Michalak, M; Pytel, E; Wojdan, K, 2012) |
| "Pathogenesis of hypertension is modulated at least in part by vascular inflammation." | ( Hara, Y; Okada, M; Usui, T; Yamawaki, H, 2012) |
| "Resistant hypertension is defined as blood pressure (BP) that remains above goal (such as 140/90 mmHg or more) in spite of the concurrent use of three antihypertensive agents of different classes." | ( Agarwal, R, 2012) |
| "Hypertension is highly prevalent among renal transplant recipients (RTR) and a risk factor for graft failure and cardiovascular events." | ( Bakker, SJ; Brink, EJ; Engberink, MF; Gans, RO; Navis, G; van Baak, MA; van den Berg, E, 2013) |
| "Hypertension is common in people aged 65 and older." | ( Bakris, GL; Oliva, RV, 2012) |
| "Hypertension is major risk factor leading to cerebrovascular pathologies." | ( Delibas, N; Kirbas, A; Kirbas, S; Kutluhan, S; Sutcu, R, 2012) |
| "Hypertension is an important side effect of sunitinib treatment." | ( Boven, E; Eechoute, K; Gelderblom, H; Guchelaar, HJ; Haanen, JB; Kappers, MH; Mathijssen, RH; Oosting, S; Reyners, AK; van der Veldt, AA; van Herpen, CM; Wessels, JA, 2012) |
| "A hallmark of hypertension is an increase in arterial myocyte voltage-dependent Ca2+ (CaV1." | ( Bannister, JP; Bulley, S; Jaggar, JH; Luzny, P; Narayanan, D; Pachuau, J; Thomas-Gatewood, C, 2012) |
| "Hypertension is associated with certain target organ damage (TOD) and related clinical conditions." | ( Altun, B; Apikoglu, M; Ay, SA; Balta, S; Bulucu, F; Demirbas, S; Demirkol, S; Gokce, G; Karaman, M; Saglam, K; Yaman, H, 2013) |
| "Arterial hypertension is a major risk factor for ischemic stroke." | ( Kang, BT; Kim, DE; Leoni, RF; Silva, AC, 2012) |
| "Hypertension is a major health problem and a main risk factor for cardiovascular diseases." | ( Elnakish, MT; Hassanain, HH; Janssen, PM, 2012) |
| "Hypertension is one of the common diseases in the elderly." | ( Higashi, Y; Kihara, Y; Noma, K, 2012) |
| "Hypertension is a major and common threat to the health of individuals around the world." | ( Cao, J; Pan, D; Wu, Z; Zhen, X, 2013) |
| "Postoperative hypertension is a common problem in patients undergoing surgical procedures, and the modification of this response could result in improved surgical outcome." | ( Adhikary, SD; Babu, SK; Korula, G; Ramachandran, A; Vedantam, R; Velayutham, PK, 2013) |
| "Hypertension is the most common comorbidity among heart failure (HF) patients and has been independently linked with cognitive impairment." | ( Alosco, ML; Brickman, AM; Cohen, R; Colbert, LH; Gunstad, J; Hughes, J; Josephson, R; Raz, N; Rosneck, J; Spitznagel, MB; Sweet, LH; van Dulmen, M, 2012) |
| "Hypertension is associated with an elevation in agonist-induced vasoconstriction, but mechanisms involved require further investigation." | ( Adebiyi, A; Jaggar, JH; Kidd, MW; Leo, MD; Neeb, ZP; Thomas-Gatewood, CM, 2012) |
| "Although hypertension is thought to be associated with a high incidence of stroke, not all patients with unruptured cerebral aneurysms are hypertensive." | ( Kanematsu, Y; Kitazato, KT; Matsushita, N; Nagahiro, S; Satomi, J; Shimada, K; Sumiyoshi, M; Tada, Y; Yagi, K, 2012) |
| "Arterial hypertension is a major risk factor that can lead to complication of peripheral vascular disease due, in part, to endothelial dysfunction." | ( Amin, A; Badr El-Din, NK; Choi, SK; Kadowitz, P; Kevil, CG; Matrougui, K; Navar, LG; Osman-Elazeik, Y; Trebak, M, 2012) |
| "Hypertension is a leading cause of cardiovascular morbidity and mortality, and uncontrolled hypertension remains common despite the availability of several classes of effective antihypertensive medications." | ( Huan, Y; Townsend, R, 2012) |
| "Endocrine hypertension is the most common cause of secondary hypertension affecting ~3 % of the population, with primary hyperaldosteronism and pheochromocytoma being the principal conditions." | ( Al-Salameh, A; Chanson, P; Cohen, R; Plouin, PF, 2012) |
| "Hypertension is common following renal transplantation, affecting up to 80% of transplant recipients." | ( Arias Rodríguez, M; Cabello Chaves, V; Campistol Plana, JM; Díz Gómez, JM; Fernandez Fresnedo, G; Franco Esteve, A; Gallego Samper, R; Gallego Valcárcel, E; Gómez Huertas, E; Marín Iranzo, R; Osorio Moratalla, JM, 2012) |
| "Hypertension is associated with enhanced cardiac sympathetic transmission, although the exact mechanisms underlying this are still unknown." | ( Mane, S; Paterson, DJ; Ryan, R; Shanks, J, 2013) |
| "Since resistant hypertension is also characterized by enhanced sympathetic activity, it seems logical and biologically plausible, that RSD might favorably influence impaired glucose metabolism, sleep disorders and increased body adiposity beyond BP lowering." | ( Anastasopoulos, I; Ioannidis, I; Kyriazis, I; Spanoudi, F; Thomopoulos, C, 2013) |
| "Hypertension is a major public health problem." | ( Alshaarawy, O; Shankar, A; Xiao, J, 2013) |
| "Hypertension is the leading cause." | ( Koga, M; Toyoda, K, 2012) |
| "Hypertension is a modifiable risk factor for cardiovascular diseases and is associated with several metabolic disorders like dyslipidemia." | ( Akhan, M; Arslan, E; Arslan, Z; Ay, SA; Balta, S; Bulucu, F; Cakar, M; Celik, T; Demirbas, S; Demirkol, S; Karaman, M; Saglam, K; Sarlak, H, 2013) |
| "Hypertension is accompanied by increased levels of reactive oxygen species, which may contribute to progressive renal injury and dysfunction." | ( Amaral, JS; Gomes, P; Lemos, V; Simão, S; Soares-da-Silva, P, 2013) |
| "Arterial hypertension is associated with a high production of reactive oxygen species and a decrease in the antioxidant defense systems." | ( Blanca, AJ; Mate, A; Miguel-Carrasco, JL; Revilla, E; Ruiz-Armenta, MV; Santa-María, C; Vázquez, CM; Zambrano, S, 2013) |
| "Chronic hypertension is associated with an impaired vascular relaxation caused by an increased vascular tone; however, the underlying mechanisms are not fully understood in human patients." | ( Cheng, J; Li, PY; Liu, ZF; Mao, L; Tan, XQ; Wen, J; Yang, Y; Zeng, XR, 2013) |
| "Hypertension is associated with an increased cancer mortality and a higher kidney cancer risk." | ( Amann, K; Brand, S; Schupp, N, 2013) |
| "Hypertension is a primary cardiovascular risk factor." | ( Arangino, S; Cagnacci, A; Ferrari, S; Napolitano, A; Piacenti, I; Volpe, A, 2013) |
| "Human essential hypertension is partly caused by genetic factors." | ( Ataka, Y; Eddie, R; Furusawa, T; Inaoka, T; Ishida, T; Kimura, R; Matsumura, Y; Naka, I; Nakazawa, M; Natsuhara, K; Ohashi, J; Ohtsuka, R; Yamauchi, T, 2013) |
| "Hypertension is a serious disease that often develops in obesity, but it is not clear how obesity increases the risk of hypertension." | ( Cowley, MA; Simonds, SE, 2013) |
| "As hypertension is a long-term disease, we presently test the hypothesis that a longer (30 day) 5-HT infusion could cause a sustained fall in blood pressure in the established hypertensive DOCA-salt rat." | ( Burnett, R; Davis, RP; Garver, H; Szasz, T; Tykocki, NR; Watts, SW, 2013) |
| "Hypertension is a major risk factor for death and cardiovascular disease (CVD) in patients undergoing chronic haemodialysis (HD), but there is uncertainty surrounding the effects of blood pressure (BP) lowering on this high-risk patient group." | ( Arima, H; Iseki, K; Kohagura, K; Komiya, I; Shiohira, Y; Tokuyama, K; Toma, S; Ueda, S; Uehara, H, 2013) |
| "Established hypertension is associated with abnormal exercise hemodynamics and reduced exercise capacity through mechanisms that may include contributions from arterial stiffness and endothelial vasomotor dysfunction." | ( Attinà, TM; Drummond, ID; Malatino, LS; Maxwell, SR; Webb, DJ, 2013) |
| "Hypertension is associated with cerebral small vessel disease (SVD) and with diffuse white matter hyperintensities (WMH) on T2-weighted magnetic resonance imaging (MRI)." | ( Barrick, TR; Bridges, LR; Brittain, JF; Dominiczak, AF; Graham, D; Hainsworth, AH; Holmes, WM; Kaushal, N; Khatun, H; McCabe, C; Mhairi Macrae, I, 2013) |
| "Hypertension is the result of interaction between genetic vulnerability and exposure to unhealthy lifestyle." | ( Asotra, S; Bhardwaj, R; Ganju, N; Kandoria, A; Kanwar, A; Marwaha, R; Negi, PC; Sharma, R, 2012) |
| "The prevalence of hypertension is high and is associated with socio-demographic factors." | ( Durge, PM; Gupta, SS; Kokiwar, PR, 2012) |
| "Hypertension is a serious worldwide public health problem." | ( Guo, L; Li, H; Mi, K; Ou, X; Sun, M; Wu, J; Yin, N; Zhang, G, 2013) |
| "Hypertension is identified as the main precursor of left ventricular hypertrophy and therefore can lead to diastolic dysfunction and heart failure." | ( de Assis, LV; Isoldi, MC; Locatelli, J, 2014) |
| "Hypertension is a major public health problem worldwide." | ( Chaudhuri, D; Das, N; Dey, S; Ganguli, D; Ghosh, S; Saha, I, 2013) |
| "Morning hypertension is a risk factor for cardiovascular and cerebrovascular events." | ( Hiramatsu, K; Kario, K; Komiya, M; Sato, Y; Shimada, K; Shiosakai, K; Shirayama, M; Takahashi, M, 2013) |
| "Morning hypertension is a risk factor for cardiovascular and cerebrovascular events, and consequently diagnosis and control of morning hypertension are considered very important." | ( Hiramatsu, K; Kario, K; Komiya, M; Shimada, K; Shiosakai, K; Shirayama, M; Takahashi, M; Uehara, Y, 2013) |
| "Hypertension is accompanied by structural remodelling of vascular extracellular matrix (ECM)." | ( Basu, R; Davidge, ST; Fan, D; Kandalam, V; Kassiri, Z; Lee, J; Morton, JS; Takawale, A; Wang, X, 2013) |
| "Hypertension is considered an independent risk factor for cardiovascular mortality in diabetic patients." | ( Bahrami, A; Farsi, L; Kamran, M; Keshavarz, M; Soltani, N, 2013) |
| "Hypertension is a condition which in many cases is treated with more than one drug." | ( Freytag, S; Hagendorff, A; Klebs, S; Müller, A, 2013) |
| "Hypertension is a common comorbidity among diabetic patients." | ( Azah, AS; Cheong, AT; Salmiah, MS; Sazlina, SG; Tong, SF, 2015) |
| "The prevalence of hypertension is high in China." | ( Chen, Y; Ding, L; He, L; Huang, Z; Jin, Y; Qi, Q; Song, X; Tang, H; Wang, Q; Yao, Y; Yu, J, 2013) |
| "Hypertension is one of the most prominent risk factors for coronary artery disease (CAD)." | ( Achenbach, S; Cicha, I; Garlichs, CD; Klinghammer, L; Lewczuk, P; Raaz-Schrauder, D; Urschel, K, 2013) |
| "Arterial hypertension is a multifactorial chronic condition caused by either congenital or acquired factors." | ( Aires, MB; Araujo, AJ; Fioretto, ET; Mota, MM; Santana-Filho, VJ; Santos, AC; Santos, MR; Souza, Kdos S, 2013) |
| "Hypertension is often inadequately controlled in older people." | ( Fernandez, V; Heyrman, R; Izzo, JL; Lee, J; Lewin, AJ; Melino, M, 2013) |
| "Obesity and hypertension are comorbid in epidemic proportion, yet their biological connection is largely a mystery." | ( Burnett, R; Charvat, TT; Dorrance, AM; Fink, GD; Penfold, ME; Rourke, JL; Seitz, B; Sinal, CJ; Sullivan, TJ; Thompson, JM; Watts, SW, 2013) |
| "Hypertension is a major challenge for public health." | ( Arslan, E; Ay, SA; Balta, S; Bozoglu, E; Bulucu, F; Cakar, M; Celik, T; Demirbas, S; Demirkol, S; Karaman, M; Kurt, O; Naharci, MI, 2013) |
| "Hypertension is closely associated with significant ARAS." | ( Jayaram, AA; Kute, VB; Madan, TH; Manjunath, AP; Rawal, JR; Shukla, AN; Udhreja, S, 2013) |
| "Hypertension is traditionally considered a disease in which elevated blood pressure contributes to inflammation and activation of the immune system, leading to cardiovascular injury and end-organ damage." | ( Barake, MF; Campino, C; Fardella, CE; Kalergis, AM; Letelier, NA; Muñoz-Durango, N, 2013) |
| "Hypertension is one of the leading causes of morbidity and mortality in Brazil." | ( da Silva Nalin de Souza, B; França, AK; Lima, ST; Salgado Filho, N; Sichieri, R, 2013) |
| "Hypertension is also associated with CO/DY." | ( Balafa, O; Kalaitzidis, RG; Karasavvidou, D; Pappas, K; Pelidou, SH; Siamopoulos, KC; Spanos, G; Tatsioni, A, 2013) |
| "Prehypertension is one of the primary causes of major cardiovascular events independent from other cardiovascular risk factors." | ( Akkoyun, DC; Akyüz, A; Alpsoy, Ş; Değirmenci, H; Oran, M; Topcu, B, 2013) |
| "Hypertension is a major modifiable risk factor associated with cardiovascular morbidity and mortality." | ( Jonas, JB; Lamoureux, EL; Nangia, V; Sabanayagam, C; Wong, TY; Yip, W; Zheng, Y, 2013) |
| "Hypertension is the most frequent condition associated with atrial fibrillation (AF) and stroke, the most terrible complication of AF." | ( Barrios, V; Escobar, C, 2013) |
| "Hypertension is recognized as a major risk factor for coronary, cerebral and renal vascular disease." | ( Arangino, S; Cagnacci, A; Napolitano, A; Volpe, A; Zanin, R, 2013) |
| "The hypertension is a civilization disease, slowly destroying the cardio-vascular system and leading to serious complications, which may result in patient death." | ( Jaźwińska-Tarnawska, E; Szczotka, B; Wedlarski, R; Wiela-Hojeńska, A; Łapiński, Ł, 2013) |
| "Hypertension is an extremely prevalent cardiovascular risk factor and current antihypertensive therapies do not adequately treat hypertension in many affected individuals." | ( Barrett, KV; Jaffe, IZ; McCurley, AT, 2013) |
| "Hypertension is a frequent complication of type 2 diabetes mellitus (DM) because of the close etiological relationship between these two diseases." | ( Akehi, Y; Murase, K; Nagaishi, R; Nomiyama, T; Takenoshita, H; Yanase, T, 2013) |
| "Angina and hypertension are common in patients with coronary artery disease (CAD); however, the effect on mortality is unclear." | ( Cooper-Dehoff, RM; Gong, Y; Handberg, EM; Pepine, CJ; Winchester, DE, 2013) |
| "Essential hypertension is associated with abnormalities in dopamine production, receptor number, and/or posttranslational modification." | ( Armando, I; Jose, PA; Villar, VA, 2011) |
| "Arterial hypertension is an important risk factor for cerebrovascular diseases, such as transient ischemic attacks or stroke, and represents a major global health issue." | ( Buck, A; Calcinaghi, N; Fritschy, JM; Jolivet, R; Keller, AL; Matter, CM; Singh, A; Weber, B; Winnik, S; Wyss, MT, 2013) |
| "Hypokalemia and hypertension are common manifestations of preclinical cardiovascular conditions that have a predictive value for cardiovascular morbidity and mortality." | ( Chang, CC; Liu, CT; Liu, MY; Mo, FE; Periasamy, S, 2014) |
| "Hypertension is an important modifiable risk factor for coronary heart disease, congestive heart failure, stroke, end-stage renal disease, and peripheral vascular disease, but many of the molecular mechanisms and genetic factors underlying the development of the most common forms of human hypertension remain to be defined." | ( Buys, ES; Sips, PY, 2013) |
| "Acute hypertension is common following stroke and contributes to poor outcomes." | ( Coplin, W; Levy, PD; Liu-DeRyke, X; Parker, D; Rhoney, DH, 2013) |
| "Hypertension is a risk factor for several cardiovascular diseases and oxidative stress suggested to be involved in the pathophysiology." | ( Govindasamy, C; Mustapha, Z; Nik Yusoff, NS; Sirajudeen, KN, 2013) |
| "Hypertension is accompanied by thickening of arteries, resulting in marked changes in their passive and active mechanical properties." | ( Török, J; Zemancíková, A, 2013) |
| "Pathogenesis of hypertension is regulated in part by vascular inflammation." | ( Hara, Y; Okada, M; Usui, T; Yamawaki, H, 2013) |
| "Hypertension is a major risk factor in addition to atherosclerosis and type 2 diabetes mellitus for the development of coronary heart disease and strokes." | ( Chrysant, GS; Chrysant, SG, 2013) |
| "Hypertension is known to be one of the main risk factors for cardiovascular disease." | ( Carbone, A; Cicero, AF; D'Angelo, A; Derosa, G; Fogari, E; Maffioli, P; Querci, F, 2013) |
| "Arterial hypertension is highly prevalent but poorly controlled." | ( Baumgart, P; Bramlage, P; Buhck, H; Gitt, AK; Mahfoud, F; Potthoff, SA; Schmieder, RE; Schneider, S; Senges, J, 2013) |
| "Hypertension is frequent in chronic hemodialyzed patients and usually treated by reducing extracellular fluid." | ( Fischbach, M; Krid, S; Niaudet, P; Salomon, R; Schaefer, B; Schaefer, F; Schmitt, CP; Zaloszyc, A, 2013) |
| "Hypertension is not always related to overhydration." | ( Fischbach, M; Krid, S; Niaudet, P; Salomon, R; Schaefer, B; Schaefer, F; Schmitt, CP; Zaloszyc, A, 2013) |
| "Although hypertension is the most common risk factor for thoracic aortic diseases, it is not understood how increased pressures on the ascending aorta lead to aortic aneurysms." | ( Brasier, AR; Cao, JM; Geng, L; Guo, S; Kuang, SQ; Kwartler, CS; Milewicz, DM; Peters, AM; Prakash, SK; Villamizar, C, 2013) |
| "Primary hypertension is associated with decreased performance on neurocognitive testing and a blunted cerebrovascular reactivity to hypercapnia." | ( Brosgol, Y; Kupferman, JC; Lande, MB; Ostrovskaya, MA; Paterno, K; Pavlakis, SG; Rojas, M, 2015) |
| "Hypertension is a leading cause of death and disability globally, and its prevalence continues to accelerate." | ( Cortes, SF; Cruz, JS; da Silva, JP; de Souza, Mde F; Gomes, RA; Lemos, VS; Pereira, AC; Rezende, BA; Silva, GC; Teles, YC, 2013) |
| "Hypertension is regulated through both the central and systemic renin-angiotensin systems." | ( Li, F; Lin, YL; Liu, C; Yang, Y, 2013) |
| "Hypertension is characterized by endothelial dysfunction and we hypothesized that a single-dose of atorvastatin may have an acute effect on vascular function." | ( Andersson, O; Bergh, N; Grote, L; Hrafnkelsdóttir, TJ; Saluveer, O; Widgren, BR, 2013) |
| "Hypertension is a common health problem with serious consequences for individuals and a heavy attributable burden for populations." | ( Plouin, PF; Steichen, O, 2014) |
| "Hypertension is an important risk factor for kidney failure and renal events in the general population." | ( Calignano, A; d'Emmanuele di Villa Bianca, R; Mattace Raso, G; Meli, R; Mitidieri, E; Orefice, NS; Paciello, O; Pagano, TB; Pirozzi, C; Russo, R; Santoro, A; Simeoli, R, 2013) |
| "Hypertension is an established risk factor for stroke, premature coronary artery disease and heart failure." | ( Andersen, K, 2013) |
| "Essential hypertension is one of the major contributors to premature morbidity and mortality due to the incresased risk for coronary heart disease, stroke, renal disease, peripheral vascular disease and vascular dementia for both men and women." | ( Arias de Saavedra-Alías, JM; Liébana-Cañada, A; Martínez-Martos, JM; Ramírez-Expósito, MJ; Sánchez-Agesta Ortega, R; Sánchez-Muñoz, B, 2013) |
| "Hypertension is a common chronic condition in many patients requiring anesthesia." | ( Thoma, A, 2013) |
| "Hypertension is a key factor of cardiovascular disease." | ( Fujita, T; Horita, S; Koike, K; Seki, G; Suzuki, M; Yamada, H, 2013) |
| "Hypertension is a complex interplay of interrelated etiologies, and the leading risk factor for many cardiovascular morbidity and mortality worldwide." | ( Ndisang, JF; Tiwari, S, 2014) |
| "Prehypertension is highly prevalent in urban population of India, more often seen in persons below 50 years of age." | ( Amarkhed, B; Ambar, S; Halkati, PC; Patil, R; Patted, SV; Porwal, SC; Yavagal, ST, 2013) |
| "Hypertension is a major risk factor for cardiovascular diseases and is detrimental to several organs including the liver and kidneys." | ( Al-Bishri, WM, 2013) |
| "Hypertension is associated with the impairment of renal cyclooxygenase (COX) activity, which regulates vascular tone, salt and water balance and renin release." | ( D'Abril Ruíz-Leyja, E; Estrada-Soto, SE; Gallardo-Ortíz, IA; Ibarra-Barajas, M; López-Guerrero, JJ; Villalobos-Molina, R, 2013) |
| "Hypertension is highly prevalent and remains poorly controlled." | ( Cohen, DL; Denker, MG; Haddad, DB; Townsend, RR, 2013) |
| "Hypertension is a major risk factor for CVD, the leading cause of mortality worldwide." | ( Hanson, MG; Taylor, CG; Zahradka, P, 2014) |
| "The prevalence of hypertension is high in patients with diabetes mellitus (DM), chronic kidney disease (CKD) and chronic cardiovascular disease (CVD), as well as in black and elderly subjects." | ( Chrysant, SG, 2013) |
| "Hypertension is a significant risk factor for cardiovascular disease, and epidemiological evidence suggests that it is increasing in parallel with obesity in children and adolescents in low- and middle-income countries." | ( Anthony, D; Dyson, PA; Fenton, B; Matthews, DR; Stevens, DE, 2014) |
| "Essential hypertension is associated with an exaggerated natriuresis in response to intravenous infusion of isotonic saline." | ( Frøkiær, J; Thomsen, K; Wang, G, 2013) |
| "Hypertension is one of the most frequent chronic disease in Hungary and one of the most important cardiovascular risk factor." | ( Simonyi, G, 2013) |
| "Hypertension is commonly associated with peripheral artery disease." | ( Aliani, M; Dibrov, E; Edel, AL; Guzman, R; LaVallee, R; Maddaford, TG; Pierce, GN; Pinneker, R; Ramjiawan, B; Rodriguez-Leyva, D; Weighell, W, 2013) |
| "Systemic arterial hypertension is a strong and prevalent cardiovascular risk factor." | ( Boiten, HJ; Ottenhof, MJ; Schinkel, AF; Valkema, R; van Domburg, RT; Wai, MC, 2013) |
| "Persistent AF and hypertension are independent risk factors for late AF recurrence after pulmonary vein isolation." | ( Balsam, P; Kiliszek, M; Kochanowski, J; Koźluk, E; Lodziński, P; Opolski, G; Piątkowska, A; Piątkowski, R; Scisło, P, 2014) |
| "Hypertension is a major public health problem in Malaysia." | ( Chan, TC; Loh, HY; Loh, KW; Moy, FM; Ng, CW; Rani, F, 2013) |
| "Hypertension is related to tumour growth, and might be used as an additional tool to assess the potential growing capacity of the tumour." | ( Arenas, C; Melián, C; Pérez-Alenza, D, 2013) |
| "Hypertension is one of the major adverse events of this agent, but to date the incidence and risk of hypertension with regorafenib have not been systematically investigated." | ( Guan, X; Huang, G; Nie, W; Tang, J; Wang, Z; Xu, J, 2014) |
| "Hypertension is a disease accompanied by endothelial dysfunction and is characterized by an impaired vascular reactivity and enhanced activity of sympathetic nervous system." | ( Kristova, V; Liskova, S; Petrova, M; Varga, Z; Villaris, R; Vojtko, R; Zicha, J, 2013) |
| "Abstract Hypertension is considered as a chronic and complex disease relating to multiple systemic systems." | ( He, Y; Wang, W; Yang, Q, 2014) |
| "Hypertension is a clinical syndrome characterized by increased arterial tone." | ( Cidad, P; Colinas, O; López-López, JR; Pérez-García, MT; Santana, LF; Tajada, S, 2013) |
| "Hypertension is the most common adverse effect of the inhibitors of vascular endothelial growth factor (VEGF) pathway-based therapy (VEGF pathway inhibitors therapy, VPI therapy) in cancer patients." | ( Kruzliak, P; Novák, J; Novák, M, 2014) |
| "Hypertension is a highly prevalent disorder and a major risk factor for cardiovascular diseases." | ( Kost, CK; Li, S; Li, Y; Martin, DS; Wang, X, 2013) |
| "Hypertension is associated with low-grade inflammation, and Toll-like receptor 4 (TLR4) has been shown to be linked to the development and maintenance of hypertension." | ( Chen, X; Huang, R; Lei, H; Long, S; Pei, Z; Shi, X; Su, H; Zhang, X, 2013) |
| "Isolated systolic hypertension is a highly prevalent disease among the elderly." | ( Abad-Pérez, D; García-Polo, I; Novella-Arribas, B; Rodríguez-Salvanés, FJ; Sánchez-Gómez, LM; Suárez-Fernández, C; Verge-González, C, 2013) |
| "Hypertension is an important issue in Asia, responsible for up to 66% of cardiovascular disease cases." | ( Birgit, V; Gao, PJ; Jeong, MH; Liu, SW; Mattheus, M; Zhu, DL, 2013) |
| "Hypertension is associated with end-organ damage and thus might lead to the release of damage-associated molecular patterns (DAMPs), which are endogenous activators of TLR4 receptors." | ( Aoqui, C; Baumann, M; Bluyssen, H; Chmielewski, S; Eißler, R; Heemann, U; Lorenz, S; Lutz, J; Scherer, E; Schmaderer, C; Sollinger, D; Strand, S; Witzke, O; Zicha, J, 2014) |
| "Adrenomegaly and hypertension are common clinical entities in canine medicine for which testing for pheochromocytoma is recommended." | ( Frank, EL; Green, BA, 2013) |
| "Although hypertension is a worldwide health issue, an incomplete understanding of its aetiology has hindered our ability to treat this complex disease." | ( Bai, X; Bird, KE; Kakoki, M; Lenhart, KC; Li, F; Mack, CP; Rojas, M; Smithies, O; Suen, AA; Taylor, JM, 2013) |
| "Hypertension is both a cause and a complication of CKD, and a risk factor for progression of kidney disease." | ( Fu, B; Han, Z; Meng, L; Yang, M; Zhang, T, 2014) |
| "Hypertension is also associated with vascular inflammation and increased mechanical stretch." | ( Chen, W; Harrison, DG; Kirabo, A; Madhur, MS; Saleh, MA; Thabet, SR; Trott, DW; Wu, J; Xiao, L, 2014) |
| "Systemic hypertension is a common characteristic in acute heart failure (HF)." | ( Burnett, JC; Cataliotti, A; Chen, HH; Ichiki, T; McKie, PM; Sangaralingham, SJ, 2014) |
| "Hypertension is associated with the structural remodeling and stiffening of arteries and is known to increase cardiovascular risk." | ( Gao, H; Ji, X; Li, X; Liu, X; Qiu, J; Wang, Y; You, B; Zhang, J; Zhao, S, 2014) |
| "Hypertension is the most common disease of the cardiovascular system." | ( Bregvadze, TR; Mishchuk, NE; Tseluĭko, VI, 2013) |
| "Hypertension is accompanied by high or low circulating AngII levels and cardiac/renal injury." | ( Chen, Y; Liu, C; Liu, H; Meng, W; Sun, Y; Zhao, T; Zhao, W, 2014) |
| "Hypertension is a frequent condition among individuals over 65 years of age worldwide and is one of the most important risk factors for cardiovascular (CV) disease." | ( Fabrizzi, P; Malacco, E; Mallion, JM; Omboni, S; Volpe, M, 2014) |
| "Hypertension is a major contributing factor to the current epidemic of cardiovascular disease in India." | ( Agrawal, S; Davey Smith, G; Ebrahim, S; Moser, KA, 2014) |
| "Hypertension is very common in India, even among underweight adults and those of lower socioeconomic position." | ( Agrawal, S; Davey Smith, G; Ebrahim, S; Moser, KA, 2014) |
| "Thus, hypertension is a major link between tHcy and aortic arterial stiffness." | ( Bai, J; Bai, Y; Liu, D; Luo, L; Wu, H; Xiao, W; Ye, P, 2014) |
| "Hypertension is a heritable trait that remains the most potent and widespread cardiovascular risk factor, although details of its genetic determination are poorly understood." | ( Corneveaux, JJ; Ehret, GB; Eskin, E; Hightower, CM; Huentelman, MJ; Mahata, M; Maihofer, AX; Miramontes-Gonzalez, JP; Nievergelt, CM; O'Connor, DT; Pastinen, T; Rao, F; Saier, MH; Schork, AJ; Schork, NJ; Sun, EI; Waalen, J; Wei, Z; Zhang, K, 2014) |
| "Hypertension is an important risk factor for liver damage and several other circulatory abnormalities." | ( Kamal, SM, 2013) |
| "Hypertension is a widespread and frequently progressive ailment that imparts a foremost threat for cardiovascular and renal disorders." | ( Ahmad, W; Amjad, MW; Bukhari, SN; Butt, AM; Shah, VH; Trivedi, AR, 2013) |
| "Essential hypertension is frequently associated with hyperuricemia in both adult and pediatric patients." | ( Assadi, F, 2014) |
| "Hypertension is prevalent in Yi populations." | ( Chen, T; Gao, Y; Ran, XW; Ren, Y; Tian, HM; Xie, XH, 2014) |
| "Hypertension is a major modifiable risk for the development of cardiovascular, cerebrovascular and renal diseases." | ( de la Sierra, A; Kreutz, R; Laurent, S; Manolis, AJ; Volpe, M, 2014) |
| "Hypertension is the major modifiable risk factor for cardiovascular and renal disease and reflects underlying abnormalities of Na(+) homeostasis." | ( Bailey, MA; Hunter, RW; Ivy, JR, 2014) |
| "Indeed, hypertension is surgically curable in a minority of patients, mostly in patients with aldosterone-secreting adenomas or with pheochromocytomas or functional paragangliomas." | ( Amar, L; Azizi, M; Giavarini, A; Lorthioir, A; Plouin, PF, 2014) |
| "Hypertension is defined as blood pressure >=130/85 (mm Hg)." | ( Choong, LC; Hejazi, N; Huang, MS; Lin, KG, 2013) |
| "Hypertension is one of the major side effects of sorafenib, and reported incidences vary substantially among clinical trials." | ( Chen, J; Guo, H; Li, S; Li, Y; Liang, X; Meng, H; Shi, B; Zhang, D; Zhu, Y, 2014) |
| "Systemic hypertension is an important public health problem and a significant cause of cardiovascular mortality." | ( Abizaid, A; Amodeo, C; Armaganijan, D; Armaganijan, L; Borelli, F; Moraes, A; Moreira, D; Sousa, A; Sousa, JE; Sousa, M; Staico, R, 2014) |
| "Hypertension is common in Asian populations and is a major cause of cardiovascular diseases." | ( Cheung, BM; Cheung, TT, 2014) |
| "Hypertension is a major risk factor for cerebrovascular diseases, leading to vascular dementia and neurodegeneration." | ( Alò, R; Avolio, E; Canonaco, M; Facciolo, RM; Mahata, SK; Mantuano, E; Mele, M; Talani, G, 2014) |
| "Hypertension is a risk factor for other cardiovascular diseases and endothelial dysfunction was found in humans as well as in various commonly employed animal experimental models of arterial hypertension." | ( Bernatova, I, 2014) |
| "Hypertension is a major cardiovascular (CV) risk factor, and blood pressure (BP)-lowering treatment substantially reduces the risk." | ( Chwallek, F; Pimenta, E; Wang, JG, 2014) |
| "For this reason, hypertension is included as a major risk factor in the available models for the risk stratification and the prevention of thromboembolism in patients with atrial fibrillation." | ( Ghiadoni, L; Taddei, S; Virdis, A, 2014) |
| "Prevalence of hypertension is high among bank employees." | ( Deivanai Sundaram, N; Ganesh Kumar, S, 2014) |
| "Obesity-related hypertension is associated with increased activity of the renin-angiotensin-aldosterone system (RAAS), increasing arterial stiffness." | ( Chaudhuri, D; Collier, SR; Curry, CD; Frechette, V; Gowdar, R; Ji, H; Meucci, M; Moody, AM; Sandberg, K, 2015) |
| "Hypertension is a highly prevalent disease associated with cardiovascular morbidity and mortality." | ( Cataliotti, A; Holditch, SJ; Ikeda, Y; Oehler, EA; Schreiber, CA; Tonne, JM, 2014) |
| "Hypertension is the most prevalent obesity comorbidity associated with increased cardiovascular risk." | ( Nimkevych, O; Uwaifo, GI; Varughese, AG, 2014) |
| "Hypertension is a major risk factor for cardiovascular mortality, as it acts through its effects on target organs, such as the heart and kidneys." | ( Odia, OJ; Ofori, SN, 2014) |
| "Hypertension is an important contributor to both bleeding and hematoma formation during and after surgery, ultimately affecting functional and cosmetic outcomes." | ( Aylward, J; Larson, RJ, 2014) |
| "Essential hypertension is linked to an increased sympathetic vasoconstrictor activity and reduced tissue perfusion." | ( Gliemann, L; Hellsten, Y; Mortensen, SP; Nyberg, M; Saltin, B; Thaning, P, 2014) |
| "Hypertension is a modifiable cardiovascular risk factor." | ( Bassett, K; Musini, VM; Nazer, M; Wright, JM, 2014) |
| "Hypertension is one of the most common co-existing conditions in patients with chronic pain, and the potential effects of an analgesic on heart rate and blood pressure are of particular concern for patients with hypertension." | ( Biondi, DM; Etropolski, M; Moskovitz, B; Xiang, J, 2014) |
| "Management of hypertension is one of the fundamental interventions in dialysis patients." | ( Liu, W; Song, Z; Sun, Z; Tang, B; Wen, P; Yang, J; Ye, H, 2014) |
| ""Prehypertension" is the clinical stage leading to hypertension." | ( Biswas, OS; Gonzalez, VR; Schwarz, ER, 2015) |
| "Hypertension is associated with dyslipidemia." | ( Akinpelu, AO; Maruf, FA; Salako, BL, 2014) |
| "Hypertension is an important mediator of cardiac damage and remodelling." | ( de Boer, RA; Frenay, AR; Hillebrands, JL; Leuvenink, HG; Pasch, A; Snijder, PM; van Goor, H, 2015) |
| "Hypertension is an established risk factor for renal cell cancer (RCC)." | ( Deckers, IA; Godschalk, RW; Keszei, AP; Schouten, LJ; van den Brandt, PA; van Engeland, M; van Schooten, FJ, 2015) |
| "We can suggest that hypertension is an idiosyncratic side effect unrelated to the dosage." | ( Demirag, G; Kemal, Y; Kut, E; Teker, F; Yilmaz, B; Yucel, I, 2014) |
| "Resistant hypertension is defined as failure to achieve target blood pressure of < 140/90 mmHg while on full doses of an appropriate three-drug regimen that includes a diuretic." | ( Chia, YC; Ching, SM, 2014) |
| "Resistant hypertension is present in nearly one in ten hypertensive patients on treatment." | ( Chia, YC; Ching, SM, 2014) |
| "Hypertension is thought to be a significant modifying factor in the progression of renal failure in ADPKD." | ( Elumalai, R; Lakkakula, B; Periyasamy, S; Ramanathan, G, 2014) |
| "Hypertension is a major risk factor for peripheral artery disease (PAD)." | ( Baraniuk, S; Basile, JN; Dart, RA; Davis, BR; Ellsworth, AJ; Fendley, H; Habib, GB; Piller, LB; Probstfield, JL; Rahman, M; Simpson, LM; Whelton, PK, 2014) |
| "Hypertension is a common consequence of obesity." | ( Flynn, C, 2014) |
| "Hypertension is the leading risk factor for cardiovascular disease, but its cause is not always known." | ( Anderson, TJ; Bushnik, T; D'Amour, M; Levallois, P; McAlister, FA, 2014) |
| "Hypertension is a major clinical complication of obesity." | ( Evans, RG; Fernandez, S; Head, GA; Karim, F; Kaye, DM; Rajapakse, NW; Straznicky, NE, 2014) |
| "Hypertension is a very common cardiovascular disease influenced by multiple genetic and environmental factors." | ( Chen, Y; Gao, J; Guan, M; Lan, Y; Li, Y; Li, Z; Liu, Y; Yang, J; Zhu, C, 2014) |
| "Systolic hypertension is the most common form of hypertension in elderly patients." | ( Baschiera, F; Brunel, P; Chang, W, 2014) |
| "Hypertension is the most prevalent and significant modifiable risk factor for coronary heart disease." | ( Barbaro, NR; Calhoun, DA; de Faria, AP; Fontana, V; Modolo, R; Moreno, H; Nascimento, BB; Paganelli, MO; Ramos, CD; Sabbatini, AR, 2015) |
| "Hypertension is often associated with skeletal muscle pathological conditions related to function and metabolism." | ( Camerino, GM; Cannone, M; Conte Camerino, D; Conte, E; De Bellis, M; Fraysse, B; Liantonio, A; Pierno, S; Scaramuzzi, A; Tricarico, D, 2014) |
| "Hypertension is considered as a low-grade inflammatory disease, with adaptive immunity being an important mediator of this pathology." | ( Aguado, A; Alonso, MJ; De Batista, PR; Hernanz, R; Martín, A; Médici, CT; Palacios, R; Rossi, EM; Salaices, M; Silva, MA; Vassallo, DV, 2014) |
| "Hypertension is considered to be among the most important risk factors for cardiovascular and cerebrovascular diseases." | ( Arsena, R; Bono, A; Butera, D; Cottone, S; Scazzone, C; Schillaci, R; Tornese, F, 2014) |
| "Hypertension is becoming a public health emergency worldwide." | ( Singh, R; Sinha, R, 2014) |
| "Hypertension is associated with pathologically increased sympathetic drive to the vasculature." | ( Briant, LJ; Champneys, AR; Nolan, MF; Pickering, AE; Stalbovskiy, AO, 2014) |
| "Hypertension is a key risk factor for cardiovascular disease, and new treatments are needed." | ( Beattie, CJ; Dawson, J; Dominiczak, AF; Fulton, RL; Higgins, P; McCallum, L; Padmanabhan, S; Touyz, RM; Walters, MR, 2014) |
| "Hypertension is a major global health issue which elevates the risk of a large world population to chronic life-threatening diseases." | ( Bilige, M; Chen, X; Chen, Y; Kwok, LY; Liu, W; Mang, L; Shao, Y; Xue, J; Yang, J; Zhang, H, 2014) |
| "Hypertension is a chronic illness associated with high morbidity and mortality." | ( Chandrasekhar, D; Kaipanthodi, S; Mankadavath, A; Parambil, JC; Thomas, T; Zuhra, F, 2015) |
| "Hypertension is associated with cognitive deficits, particularly executive function, and decreased cerebral microvascular responsiveness to CO2 (CO2 vasoreactivity)." | ( Chui, H; Hajjar, I; Marmerelis, V; Shin, DC, 2014) |
| "Hypertension is a major cardiovascular disease risk factor, and its prevalence is markedly increased in women with SLE." | ( Gilbert, EL; Ryan, MJ, 2014) |
| "Hypertension is an important risk factor for cardiovascular disease and there is increasing evidence that inflammation and abnormal immune responses are involved in the pathogenesis of hypertension." | ( Avan, A; Ebrahimi, M; Eslami, S; Esmaeili, H; Feiz Disfani, M; Ferns, GA; Ghayour-Mobarhan, M; Mirhafez, SR; Mohebati, M; Pasdar, A; Rooki, H; Saberi Karimian, M, 2014) |
| "Hypertension is a risk factor for the cardiovascular diseases." | ( Akcali, KC; Ayaloglu-Butun, F; Demirel-Yilmaz, E; Han, S; Uludag, MO; Usanmaz, SE, 2015) |
| "Hypertension is one of the main factors causing cardiovascular diseases." | ( Kumar, S; Prahalathan, P; Raja, B; Saravanakumar, M, 2014) |
| "The prevalence of hypertension is 28% (underweight = 20%, overweight = 27%, normal = 30%)." | ( Chattopadhyay, JC; Das, PK; Khan, MM; Maiti, S; Sinha, NK, 2015) |
| "Hypertension is a major global public health problem that affects both pediatric and adult populations." | ( Basarali, MK; Ece, A; Evliyaoglu, O; Kaplan, İ; Kelekci, S; Sancaktar, E; Şen, V; Tekkeşin, N, 2014) |
| "Arterial hypertension is one of the physical complications of chronic lead exposure." | ( Akkan, T; Ayturk, M; Ozkan, E; Ozkan, S; Ozturk, MT; Tutkun, E; Yavuz, B; Yılmaz, ÖH, 2014) |
| "Hypertension is a major risk factor for cardiovascular diseases, which has been related to such changes as gradual bone loss and a decrease in bone mass index." | ( Antoniali, C; Garcia-Júnior, IR; Gealh, WC; Luvizuto, ER; Okamoto, R; Pereira, CC, 2014) |
| "This type of hypertension is thought to be a transient phenomenon not solely related to sympathetic activation and catecholamine surge but also possibly encompassing other physiologic factors." | ( Badri, AM; Bebawy, JF; Carabini, LM; Gupta, DK; Hemmer, LB; Houston, CC; Koht, A; Kosky, JL; Moreland, NC, 2015) |
| "Hypertension is one of the main cardiovascular risk factors in the elderly." | ( Arós, F; Buil-Cosiales, P; Corella, D; Covas, MI; Estruch, R; García-Valdueza, M; Gómez-Gracia, E; Lamuela-Raventos, RM; Martorell, M; Medina-Remón, A; Ortega-Calvo, M; Pinto, X; Pons, A; Ros, E; Ruiz-Gutiérrez, V; Sacanella, E; Saez, GT; Salas-Salvadó, J; Serra-Majem, L; Tresserra-Rimbau, A; Tur, JA; Vinyoles, E, 2015) |
| "Hypertension is a serious risk factor for myocardial infarction, heart failure, vascular disease, stroke, and renal failure." | ( Kaw, MK; Kumar, A; Maharjan, S; Mopidevi, B; Puri, N, 2014) |
| "Hypertension is a powerful risk factor of atrial fibrillation (AF)." | ( Chishaki, A; Hirooka, Y; Inoue, S; Kishi, T; Mukai, Y; Nagayama, T; Sunagawa, K; Takase, S; Takemoto, M, 2015) |
| "Why obesity causes hypertension is poorly understood." | ( Boggan, BM; Chambliss, KL; Mineo, C; Shaul, PW; Sundgren, NC; Tanigaki, K; Vongpatanasin, W; Yuhanna, IS, 2015) |
| "Hypertension is a widely accepted risk factor for its outcome." | ( Janik, L; Malyszko, J; Nowak, E; Przybylowski, P; Sadowski, J; Wasilewski, G, 2014) |
| "Hypertension is common in autosomal dominant polycystic kidney disease (ADPKD) and is associated with increased total kidney volume, activation of the renin-angiotensin-aldosterone system, and progression of kidney disease." | ( Abebe, KZ; Bae, KT; Braun, WE; Brosnahan, G; Chapman, AB; Czarnecki, PG; Flessner, MF; Grantham, JJ; Harris, PC; Hogan, MC; Miskulin, DC; Moore, CG; Perrone, RD; Rahbari-Oskoui, FF; Schrier, RW; Steinman, TI; Torres, VE; Winklhofer, FT, 2014) |
| "Hypertension is known as one of the most significant cardiovascular risk factors." | ( Ferenci, T; Simonyi, G, 2014) |
| "Resistant hypertension is a clinically distinct subgroup of hypertension defined by the failure to achieve blood pressure control on optimal dosing of at least 3 antihypertensive medications of different classes, including a diuretic." | ( Calhoun, DA; Judd, EK; Warnock, DG, 2014) |
| "Arterial hypertension is a considerable side effect that accompanies the clinical use of immunosuppressant drugs such as cyclosporine (CSA)." | ( El-Gowelli, HM; El-Mas, MM, 2015) |
| "Hypertension is a frequent risk factor for the development of heart failure with preserved ejection fraction (HFPEF)." | ( Borlaug, BA; Kaye, DM; Mariani, J; van Empel, VP, 2014) |
| "Hypertension is a powerful risk factor strongly linked to adverse cardiovascular outcomes." | ( Argulian, E; Grossman, E; Messerli, FH, 2015) |
| "This hypertension is associated with a decrease in nitric oxide production, activation of the endothelin-signaling pathway and renin suppression." | ( Danser, AJ; Lankhorst, S; Saleh, L; van den Meiracker, AH, 2015) |
| "Experimental hypertension is associated with increased T cell infiltration into blood pressure-controlling organs, such as the aorta and kidney; importantly in absence of T cells of the adaptive immune system, experimental hypertension is significantly blunted." | ( Diep, H; Drummond, GR; Spizzo, I; Vinh, A; Wei, Z; Widdop, RE, 2014) |
| "Hypertension is a health problem affecting over 1 billion people worldwide." | ( Carnevale, D; Cifelli, G; De Lucia, M; Fardella, S; Fardella, V; Federici, M; Iacobucci, R; Lembo, G; Pallante, F, 2014) |
| "Hypertension is the most studied etiological factor of CCCD." | ( Lebedeva, MV, 2014) |
| "While intradialytic hypertension is associated with increases in endothelin 1 relative to nitric oxide (NO), the cause of these imbalances is unknown." | ( Allen, JD; D'Silva, K; Inrig, JK; Kim, C; Molina, C; Toto, R; Van Buren, P, 2015) |
| "Hypertension is associated with endothelial dysfunction characterized by decreased vasorelaxation." | ( Alonso, GL; Carmona, M; D'Alessandro, AM; Llorens, S; Mancini, A; Nava, E; Serrano-Díaz, J, 2014) |
| "Hypertension is one of the most critical risk factors accompanying cardiovascular diseases." | ( Akama, K; Kawakami, K; Kowaka, E; Shimajiri, Y; Tongu, M, 2015) |
| "Hypertension is a high-risk symptom in atherosclerotic patients, and vascular rigidity is one of the main factors leading to hypertension." | ( Ahn, YT; An, WG; Chun, W; Kim, JM; Kim, K; Lee, C; Lee, CW; Son, Y, 2015) |
| "Hypertension is a crucial risk factor for both stroke and dementia, including Alzheimer's disease (AD)." | ( Abe, K; Deguchi, K; Hishikawa, N; Kono, S; Kurata, T; Liu, W; Yamashita, T; Zhai, Y, 2015) |
| "Because hypertension is characterized by arterial remodeling, we hypothesized that TG activity, expression, and functionality would be increased in the aorta, but not in the vena cava (which does not undergo remodeling), from hypertensive rats relative to normotensive rats." | ( Hitomi, K; Johnson, KB; Petersen-Jones, HG; Thompson, JM; Tykocki, NR; Watts, SW, 2015) |
| "Hypertension is a major risk factor for cardiovascular disease." | ( Bernstein, EA; Bernstein, KE; Giani, JF; Gonzalez-Villalobos, RA; Khan, Z; McDonough, AA; Shah, KH; Shen, XZ, 2015) |
| "Arterial hypertension is a main determinant of arterial remodelling and atherosclerosis." | ( Berti, S; Chiappino, D; Chubuchny, V; Clerico, A; Emdin, M; Januzzi, JL; Latta, DD; Maffei, S; Passino, C; Pastormerlo, LE; Prontera, C; Susini, C, 2016) |
| "Hypertension is a major risk factor for atrial fibrillation." | ( Bukowska, A; Goette, A; Heß, J; Kienitz, MC; Kockskämper, J; Nikonova, Y; Plackic, J; Pluteanu, F; Preisenberger, J; Rinne, A; Schäfer, MK; Schotten, U; Weihe, E, 2015) |
| "Essential hypertension is a complex, polygenic disease derived from the interaction of patient's genetic background with the environment." | ( Argiolas, G; Barlassina, C; Boerwinkle, E; Braga, D; Carpini, SD; Chapman, AB; Chittani, M; Citterio, L; Condorelli, G; Cooper-Dehoff, RM; Cusi, D; Dominiczak, AF; Donner, KM; Frau, F; Fresu, G; Glorioso, N; Glorioso, V; Gong, Y; Hiltunen, TP; Johnson, JA; Kontula, KK; Lanzani, C; Manunta, P; Melander, O; Ortu, MF; Padmanabhan, S; Piras, DA; Pozzoli, S; Rivera, NV; Salvi, E; Simonini, M; Trimarco, B; Troffa, C; Turner, ST; Velayutham, D; Zaninello, R, 2015) |
| "Hypertension is one of the most common cardiovascular diseases during pregnancy." | ( Chudek, J; Maruniak-Chudek, I; Olszanecka-Glinianowicz, M; Sikora, J; Wyskida, K; Wyskida, M, 2015) |
| "Essential hypertension is associated with impaired mental stress-induced nNOS-mediated vasodilator responses; this may relate to increased sympathetic outflow in hypertension." | ( Brett, SE; Chowienczyk, PJ; Fok, HW; Geer, A; Khan, SG; Shabeeh, H; Shah, AM, 2015) |
| "Hypokalaemic hypertension is the classical presentation of primary hyperaldosteronism but may also result from other mineralocorticoid activity, such as liquorice ingestion." | ( Haas, CS; Hubold, C; Lehnert, H; Muck, P; Schröder, T, 2015) |
| "Hypertension is known to impair the hyperemic response; however, the neurovascular coupling mechanisms by which this cerebrovascular dysfunction occurs have yet to be fully elucidated." | ( Filosa, JA; Higashimori, H; Iddings, JA; Kim, KJ; Zhou, Y, 2015) |
| "Systemic hypertension is one of the most prevalent cardiovascular diseases." | ( Kumar, GK; Nanduri, J; Peng, YJ; Prabhakar, NR; Yuan, G, 2015) |
| "Patients with prehypertension are more likely to progress to manifest hypertension than those with optimal or normal blood pressure." | ( Fu, F; Gao, F; He, J; Ji, L; Liang, X; Liu, F; Su, F; Su, H; Sun, X; Xing, W; Zhang, H; Zhang, W, 2015) |
| "Hypertension is a widespread condition that affects millions of people around the world and has a major impact in public health." | ( Lazartigues, E; Mendoza, A, 2015) |
| "Arterial hypertension is the most common risk factor in patients with metabolic disorders." | ( Dolidze, NM; Gezeli, TD; Tabidze, GA; Tsibadze, TA, 2015) |
| "Morning hypertension is an established risk factor for cardiovascular events." | ( Anegawa, T; Aoki, Y; Fukuda, K; Fukumoto, Y; Imaizumi, T; Iwamoto, Y; Kai, H; Uchiwa, H; Ueda, T, 2015) |
| "Resistant hypertension is common, mainly idiopathic, but sometimes related to primary aldosteronism." | ( Baguet, JP; Ducher, M; Fauvel, JP; Lantelme, P; Mounier-Véhier, C; Vaisse, B, 2015) |
| "Hypertension is one the most common causes of chronic kidney disease (CKD)." | ( Ghanei, E; Gharishvandi, F; Kazerouni, F; Nasiri, M; Rahimipour, A, 2015) |
| "Hypertension is considered an independent risk factor for cardiovascular mortality in diabetic patients." | ( Farsi, L; Keshavarz, M; Kharazmi, F; Rezaei, S; Soltani, N, 2015) |
| "Hypertension is a risk factor for cognitive impairment." | ( Bhat, SA; Goel, R; Hanif, K; Nath, C; Rajasekar, N; Shukla, R, 2015) |
| "Hypertension is associated with higher PTH levels, and specific antihypertensive medications may modulate PTH." | ( Curhan, GC; Kronenberg, H; Paik, JM; Taylor, EN; Vaidya, A, 2015) |
| "Hypertension is still treated by conventional medicine despite its exact aetiology being unknown." | ( Megat Mohd Nordin, NA; Mohd Zainudin, M; Zakaria, Z, 2015) |
| "Managing hypertension is crucial for preventing stroke recurrence." | ( Hirasawa, M; Kageji, T; Kanematsu, Y; Kitazato, KT; Kuwayama, K; Matsushita, N; Matsuura, E; Nagahiro, S; Nishi, K; Satomi, J; Shimada, K; Tada, Y; Uno, M; Yagi, K, 2015) |
| "Essential hypertension is a polygenic disorder with a complex and multifactorial nature." | ( DeLuca, HF; Plum, LA; Sundersingh, F, 2015) |
| "Hypertension is accompanied by inflammatory process and purinergic system has been recognized as having an important role in modulating immune functions." | ( Abdalla, FH; Bagatini, MD; Cardoso, AM; Jaques, JA; Leal, DB; Martins, CC; Morsch, VM; Schetinger, MR; Schmatz, R; Zanini, D, 2015) |
| "Hypertension is a highly prevalent disease worldwide." | ( Brito, R; Castillo, G; González, J; Rodrigo, R; Valls, N, 2015) |
| "Hypertension is a common finding in patients with renal impairment but it is frequently difficult to establish if one feature is the cause or the effect of the other." | ( Qadir, A, 2015) |
| "Hypertension is the largest risk factor for cardiovascular disease (CVD), and the most common life-style related disease in Japan." | ( Hasebe, N, 2015) |
| "Hypertension is a major cardiovascular risk factor." | ( Briones, AM; Dulak-Lis, M; Harvey, A; Montezano, AC; Touyz, RM; Tsiropoulou, S, 2015) |
| "Hypertension is the most common cardiovascular disease and the main risk factor for stroke, peripheral arterial disease, arterial aneurysms and kidney disease." | ( Koliński, T; Kwieczyńska, A; Marek-Trzonkowska, N; Molisz, A; Reiwer-Gostomska, M; Siebert, J, 2015) |
| "Hypertension is a major traditional risk factor for atherosclerosis, and carotid artery intima-media thickness (IMT) is considered to be an important marker of atherosclerosis." | ( Gu, J; Hu, R; Li, G; Wu, HZ, 2015) |
| "Arterial hypertension is a common disorder that affects around 9 million adults in Poland." | ( Borowiec, Ł; Filipiak, KJ; Holko, P; Kawalec, P; Stawowczyk, E, 2015) |
| "Refractory hypertension is an extreme phenotype of treatment failure defined as uncontrolled blood pressure in spite of ≥5 classes of antihypertensive agents, including chlorthalidone and a mineralocorticoid receptor antagonist." | ( Acelajado, MC; Calhoun, DA; Dudenbostel, T; Li, P; Oparil, S; Pisoni, R, 2015) |
| "Salt sensitive hypertension is characterized by increases in blood pressure in response to increases in dietary salt intake and is associated with an enhanced risk of cardiovascular and renal morbidity." | ( Majid, DS; Navar, LG; Prieto, MC, 2015) |
| "Hypertension is associated with neuroinflammation and increased sympathetic tone." | ( Bernstein, KE; Li, L; Li, Y; Lyden, P; Shah, KH; Shen, XZ; Shi, P, 2015) |
| "Arterial hypertension is frequently observed in combination with hypercholesterolemia, and this is related to accelerated atherosclerosis." | ( Ivanovic, B; Tadic, M, 2015) |
| "Hypertension is an independent risk factor for heart disease and is responsible for the increased cardiac morbidity and mortality." | ( Gao, JY; Ma, J; Ren, J; Wang, Q; Xiong, L; Xu, X; Yang, J; Yang, L, 2015) |
| "Hypertension is highly prevalent among adults, and is the most important modifiable risk factor for cardiovascular events, in particular stroke." | ( Bugeja, A; Edwards, C; Fodor, G; Hiremath, S; Kirby, A; Magner, P; McCormick, B; Ramsay, T; Ruzicka, M; van der Hoef, G; Wagner, J, 2015) |
| "Hypertension is a complex trait that often co-occurs with other conditions such as obesity and is affected by genetic and environmental factors." | ( Chen, G; de las Fuentes, L; Gu, CC; Gu, D; He, J; Hixson, J; Jacquish, C; Kelly, T; Rao, DC; Rice, TK, 2015) |
| "Essential hypertension is a major driver of cardiovascular events, including coronary artery disease, myocardial infarction, ischemic stroke and congestive heart failure." | ( Battistoni, A; Rubattu, S; Tocci, G; Volpe, M, 2015) |
| "Clinical hypertension is associated with renal inflammation and elevated circulating levels of IL-1β and IL-18." | ( Arumugam, TV; Chan, CT; Cooper, MA; Diep, H; Dowling, JK; Drummond, GR; Ferens, D; Hewitson, TD; Kemp-Harper, BK; Kett, MM; Krishnan, SM; Latz, E; Ling, YH; Mansell, A; Pinar, A; Robertson, AA; Samuel, CS; Sobey, CG; Vinh, A, 2016) |
| "Hypertension is a public health problem and increases the incidence of cardiovascular diseases." | ( Araújo, JE; Bonjardim, LR; Fontes, MT; Mota, MM; Oliveira Carvalho, V; Santos, MR; Silva, TL, 2015) |
| "Hypertension is a risk factor for cardiovascular and kidney disease and is most prevalent in African-American adults." | ( Anthony, EG; Bhatnagar, V; Lipkowitz, MS; Richard, E, 2015) |
| "Hypertension is a common disease that includes oxidative stress as a major feature, and oxidative stress impairs physiological nitric oxide (NO) activity promoting cardiovascular pathophysiological mechanisms." | ( Amaral, JH; Ferreira, GC; Montenegro, MF; Pinheiro, LC; Tanus-Santos, JE, 2015) |
| "Hypertension is one of the most important causes of cardiovascular and renal morbidity and mortality, and it represents a serious health problem in Western countries." | ( Fernández-Musoles, R; García-Tejedor, A; Gimeno-Alcañíz, JV; Manzanares, P; Ruiz-Giménez, P; Salom, JB, 2015) |
| "Hypertension is the most important cardiovascular complication of obesity, even during childhood." | ( Chiarelli, F; Chiavaroli, V; de Giorgis, T; Giannini, C; Marcovecchio, ML; Mohn, A, 2016) |
| "Arterial hypertension is accompanied by an increased oxidative stress status in the heart characterized by thiobarbituric acid reactive substances (TBARS) and nucleic acid oxidation increase." | ( Amenta, F; Di Cesare Mannelli, L; Tayebati, SK; Tomassoni, D, 2016) |
| "Because hypertension is the main risk factor for cerebral infarction and most patients with hypertension take antihypertensive drugs daily, the neuroprotective effects and mechanisms of anti-hypertensive drugs need to be investigated." | ( Choi, H; Kim, YS; Koh, SH; Lee, KY; Lee, YJ; Park, HH; Son, JW; Yoo, A, 2015) |
| "Hypertension is a chronic disease with a high prevalence, and is associated with a high risk of vascular disease and premature death." | ( Chen, Y; Cui, JG; He, YM; Wang, PW; Wang, TZ; Wang, WJ; Yang, HJ; Yang, Q; Zhang, T, 2015) |
| "Resistant hypertension is inadequately controlled blood pressure (BP) despite treatment with at least three BP-lowering drugs." | ( Brown, MJ; Caulfield, M; Cruickshank, JK; Ford, I; MacDonald, TM; McInnes, G; Morant, S; Salsbury, J; Sever, P; Webb, DJ; Williams, B, 2015) |
| "Hypertension is an important risk factor for intracerebral bleed." | ( Chandni, R; Nechikkat, S; Sasidharan, PK, 2014) |
| "Hypertension is frequent in patients with atrial fibrillation (AF) and is an independent risk factor for stroke." | ( Brueckmann, M; Clemens, A; Connolly, SJ; Ezekowitz, MD; Nagarakanti, R; Noack, H; Reilly, P; Wallentin, L; Yusuf, S, 2015) |
| "Hypertension is a major contributor to the global burden of cardiovascular diseases and its prevalence increases progressively with ageing." | ( Ashor, A; Brandt, K; Lara, J; Mathers, JC; Ogbonmwan, I; Oggioni, C; Qadir, O; Siervo, M; Zheng, D, 2015) |
| "Essential hypertension is a chronic pathology that causes long-term complications due to late diagnosis of patients, the inability to control the disease through medication, or due to the complexity of associated risk factors." | ( Buda, V; Cristescu, C; Suciu, L; Tomescu, MC; Topîrceanu, A; Udrescu, L; Udrescu, M, 2016) |
| "Hypertension is a major risk factor for both ischemic and hemorrhagic strokes regardless of stroke event with an excess of 8." | ( Aziz, ZA; Basri, HB; Hanip, MR; Lee, YY; Looi, I; Ngah, BA; Sidek, NN, 2015) |
| "Clinical hypertension is associated with raised serum IgG antibodies." | ( Bobik, A; Chan, CT; Diep, H; Drummond, GR; Ferens, D; Guzik, TJ; Kett, MM; Kim, HA; Krishnan, SM; Kyaw, TS; Lewis, CV; Lieu, M; Peter, K; Salimova, E; Samuel, CS; Sobey, CG; Tipping, P; Toh, BH; Vinh, A, 2015) |
| "Hypertension is one of the main risk factors of cardiovascular diseases." | ( Andrianantenaina, I; Pacaud, P; Piola, P; Rasetarinera, OR; Ratovoson, R; Rogier, C, 2015) |
| "Hypertension is highly prevalent in rural areas although it is significantly less treated." | ( Andrianantenaina, I; Pacaud, P; Piola, P; Rasetarinera, OR; Ratovoson, R; Rogier, C, 2015) |
| "Hypertension is a serious risk factor affecting up to 30% of the world's population with a heritability of more than 30-50%." | ( Du, J; Gao, T; Li, Q; Ran, P; Sun, L; Xiao, C; Yuan, Y, 2015) |
| "Hypertension is a critical etiology for brain ischemia." | ( Chen, CX; Li, JM; Li, SX; Zhang, P; Zhao, YN, 2015) |
| "Hypertension is common and occurs in the majority of autosomal dominant polycystic kidney disease (ADPKD) patients prior to loss of kidney function." | ( Di Lorenzo, A; Grandaliano, G; Infante, B; Schena, FP; Stallone, G, 2015) |
| "Hypertension is one of the most important risk factors in cardiovascular disease and is the most common chronic disease." | ( Cheng, Y; Wang, Y; Zhou, M, 2016) |
| "Hypertension is often accompanied by autonomic dysfunction, which is detrimental to cardiac regulation." | ( Araujo, JE; Blanco, JH; Carvalho, EE; Gardim, CB; Gastaldi, AC; Oliveira, LF; Simões, MV; Souza, HC, 2015) |
| "Hypertension is one of the leading causes of cardiovascular disease (CVD) worldwide." | ( Seven, E, 2015) |
| "Arterial hypertension is a major risk factor for cardiovascular diseases." | ( Althoff, TF; Offermanns, S; Schweda, F; Takefuji, M; Tang, C; Wang, S; Wettschureck, N; Wirth, A, 2016) |
| "Hypertension is one of the commonest diseases to be managed on out-patient basis." | ( Hanchnale, P; Hingne, V; Khair, P; Mangrulkar, S, 2015) |
| "Hypertension is considered to be the most important risk factor for the development of cardiovascular diseases." | ( Siciliano, SD; Weber, LP; Wildemann, TM, 2016) |
| "Hypertension is a common comorbidity in patients with type 2 diabetes mellitus and a major risk factor for microvascular and macrovascular disease." | ( Cain, VA; Iqbal, N; Mansfield, TA; Parikh, S; Ptaszynska, A; Weber, MA, 2016) |
| "Hypertension is among the most prevalent and catastrophic chronic diseases worldwide." | ( Crowley, SD; Griffiths, R; Jeffs, AD; Karlovich, NS; McDonough, AA; Patel, MB; Rudemiller, NP; Sparks, MA; Wu, M; Zhang, J, 2016) |
| "Hypertension is an important component of metabolic syndrome." | ( Chan, JY; Hsu, CN; Tain, YL, 2015) |
| "Interestingly, hypertension is an age-associated disease and clinical data show that by age 70, 70% of the population has hypertension and this is accompanied by oxidative stress." | ( Dikalov, SI; Dikalova, AE, 2016) |
| "Hypertension is associated with lipid peroxidation due to an impaired oxidant/antioxidant status." | ( Balci, H; Cengiz, M; Doventas, A; Erdincler, DS; Erman, H; Uzun, H; Yavuzer, H; Yavuzer, S, 2016) |
| "Intradialytic hypertension is a condition where there is an increase in blood pressure (BP) from pre- to post-hemodialysis; this condition has been recently identified as an independent mortality risk factor in hypertensive hemodialysis patients." | ( Inrig, JK; Van Buren, PN, 2016) |
| "Intradialytic hypertension is associated with extracellular volume overload in addition to acute increases in vascular resistance during dialysis." | ( Inrig, JK; Van Buren, PN, 2016) |
| "Hypertension is an important determinant of cardiovascular disease, and strict blood pressure regulation is beneficially associated with the risk for cardiovascular events or all-cause mortality." | ( Hillebrands, JL; Joles, JA; van den Born, JC; van Goor, H, 2016) |
| "In conclusion, hypertension is more likely to occur in A-allele carriers of the CYP3A4 rs4646437 variant in our cohort of mRCC patients treated with sunitinib." | ( Belaustegui, A; Boven, E; Castellano, D; Diekstra, MH; García-Donas, J; Gelderblom, H; Guchelaar, HJ; Mathijssen, RH; Rini, BI; Rodríguez-Antona, C; Swen, JJ, 2017) |
| "The early onset of hypertension is associated with improved clinical outcome in HCC patients treated with sorafenib." | ( Bisulli, M; Casadei Gardini, A; Cascinu, S; Corbelli, J; Donati, G; Faloppi, L; Foschi, FG; Frassineti, GL; Gardini, A; Giampalma, E; La Barba, G; Marisi, G; Scarpi, E; Scartozzi, M; Silvestris, N; Tamberi, S; Veneroni, L, 2016) |
| "Hypertension is a predominant risk factor for cardiovascular diseases and a major health care burden." | ( Al Olabi, R; Al Shehabi, TS; Anwar, MA; Eid, AH; Saleh, AI, 2016) |
| "Hypertension is attributed to sodium retention in the distal nephron, but 11βHSD2 is also expressed in the brain." | ( Al-Dujaili, EA; Bailey, MA; Christensen, TH; Evans, LC; Holmes, MC; Ivy, JR; Kenyon, CJ; McNairn, JA; Menzies, RI; Mullins, JJ; Seckl, JR; Wyrwoll, C, 2016) |
| "Hypertension is associated with accelerated bone loss, and the renin-angiotensin-aldosterone system is a key regulator of blood pressure." | ( Bunker, CH; Kammerer, CM; Kuipers, AL; Patrick, AL; Pratt, JH; Wheeler, VW; Zmuda, JM, 2016) |
| "Hypertension is a multifactorial condition with diverse physiological systems contributing to its pathogenesis." | ( Chapman, AB; Eadon, MT, 2016) |
| "Hypertension is an established risk factor of cardiovascular morbidity and mortality." | ( Dohi, Y, 2015) |
| "Hypertension is one of the main comorbidities associated with dyslipidemia." | ( Kato, K; Kawada, T; Kodani, E; Nishiyama, Y; Otsuka, T; Saiki, Y; Takada, H, 2016) |
| "Hypertension is a common outcome associated with obstructive sleep apnea (OSA), a prevalent yet poorly treated cardiovascular disease." | ( Bateman, R; Byrne, P; Dyavanapalli, J; Jain, V; Jameson, H; Mendelowitz, D; Wang, X, 2016) |
| "Once hypertension is considered a risk factor for coronary artery disease (CAD), the RAAS is also related to this pathology." | ( Bonfim-Silva, R; Guimarães, LO; Leal Barbosa, AA; Pereira, JF; Souza Rios, DL; Souza Santos, J, 2016) |
| "Primary hypertension is a growing concern in children because of the obesity epidemic largely attributable to western lifestyles." | ( Antolini, L; Genovesi, S; Giussani, M; Orlando, A; Pontremoli, R; Rebora, P; Stella, A; Valsecchi, MG; Viazzi, F, 2016) |
| "Hypertension is often associated with metabolic syndrome (MetS), and serves as a risk factor of MetS and its complications." | ( Ding, Y; Hou, N; Hu, X; Li, C; Liu, Y; Ma, D; Mao, J; Peng, Y; Shang, H; Sun, X; Wang, C; Wang, J; Xiao, RP; Xiao, Y; Zeng, F; Zhang, J; Zhang, X; Zhang, Y; Zheng, W, 2016) |
| "Chronic hypertension is associated with left ventricular (LV) hypertrophy and LV diastolic dysfunction with impaired isovolumic relaxation and abnormal LV filling." | ( Berdeaux, A; Bizé, A; Ghaleh, B; Hittinger, L; Jozwiak, M; Melka, J; Rienzo, M; Sambin, L; Su, JB, 2016) |
| "Hypertension is a major risk factor for cardiovascular disease." | ( Geng, X; Ng, TB; Tian, G; Wang, H; Zhang, W; Zhao, L; Zhao, Y, 2016) |
| "Diabetes and hypertension are diseases that often coexist, which increases the risk of chronic organ damages and cardiovascular complications." | ( Ionkova, I; Konstantinov, S; Krasteva, I; Simeonova, R; Vitcheva, V; Zdraveva, P, 2016) |
| "Hypertension is accompanied by perturbations to the endocannabinoid and antioxidant systems." | ( Bielawska, K; Biernacki, M; Gęgotek, A; Skrzydlewska, E; Toczek, M; Łuczaj, W, 2016) |
| "Hypertension is the leading cardiovascular risk factor globally as well as in Malaysia." | ( Abdul-Hamid, H; Abdul-Razak, S; Ambigga, KS; Ariffin, F; Daher, AM; Mat-Nasir, N; Mazapuspavina, MY; Miskan, M; Nawawi, H; Ng, KK; Nor-Ashikin, MN; Ramli, AS; Yusoff, K, 2016) |
| "Hypertension is common in the Malaysian adults." | ( Abdul-Hamid, H; Abdul-Razak, S; Ambigga, KS; Ariffin, F; Daher, AM; Mat-Nasir, N; Mazapuspavina, MY; Miskan, M; Nawawi, H; Ng, KK; Nor-Ashikin, MN; Ramli, AS; Yusoff, K, 2016) |
| "Hypertension is the leading cause of cardiovascular disease and premature death worldwide." | ( Bloomfield, G; Carrillo-Larco, RM; Dorairaj, P; Gaziano, T; Gutierrez, L; He, J; Irazola, VE; Levitt, NS; Miranda, JJ; Ortiz, AB; Rubinstein, A; Steyn, K; Wu, Y; Xavier, D; Yan, LL, 2016) |
| "Gender, age, and hypertension are associated with KD recurrence." | ( Chen, Y; Liu, Z; Wang, J; Xu, F; Zeng, C, 2016) |
| "Hypertension is associated with platelet alterations that could contribute to the development of cardiovascular complications." | ( Akinyemi, AJ; Baldissarelli, J; Belló-Klein, A; Bottari, NB; de Oliveira, LS; Goularte, JF; Morsch, VM; Oboh, G; Schetinger, MR; Thomé, GR, 2016) |
| "Hypertension is one of its major side effects, but the incidence rate and overall risk has not been systematically studied." | ( Shao, Y; Wang, K; Zhang, X, 2016) |
| "Although hypertension is a risk factor for end-stage renal disease, this complication develops in only a minority of hypertensive patients." | ( Eriksen, BO; Jenssen, TG; Mathisen, UD; Melsom, T; Schei, J; Solbu, MD; Stefansson, VTN; Wilsgaard, T, 2016) |
| "Hypertension is one of the major risk factors of cardiac hypertrophy and magnesium deficiency is suggested to be a contributing factor in the progression of this complication." | ( Aslan, M; Olgar, Y; Ozdemir, S; Ozturk, N, 2016) |
| "Hypertension is a significant comorbidity associated with insulin resistance and type-2 diabetes." | ( Al-Salami, H; Elahy, M; Lam, V; Mamo, JC; Mooranian, A; Negrulj, R; Takechi, R, 2017) |
| "Hypertension is a major risk factor for atherogenesis and heart hypertrophy, both of which are associated with specific morphological and functional changes of the myocardium." | ( Karakiulakis, G; Kouvelas, D; Manthou, ME; Papakonstantinou, E; Pourzitaki, C; Tsaousi, G, 2016) |
| "Hypertension is the leading cause of early mortality in the world, and reduction of blood pressure can help to reduce that burden." | ( Mankin, LA, 2016) |
| "Hypertension is a major disease of burden worldwide." | ( Cai, Y; Feng, B; Ke, W; Li, X; Lin, H; Liu, T; Ma, W; Tao, J; Xiao, J; Yang, Z; Zeng, W; Zhang, B, 2016) |
| "Resistant hypertension is still a challenge and reserve antihypertensive agents are often necessary to achieve blood pressure control." | ( Benck, U; Birck, R; Göttmann, U; Krämer, BK; Lammert, A; Matenaer, M; Mundt, HM, 2016) |
| "The hypertension is reversible by a low-sodium diet and by the CYP4A inhibitor HET0016." | ( Capdevila, JH; Falck, JR; Guengerich, FP; Hsu, MH; Johnson, EF; Savas, Ü; Wei, S, 2016) |
| "Obesity related hypertension is a major risk factor for resistant hypertension." | ( Giam, B; Head, GA; Kaye, DM; Kuruppu, S; Rajapakse, NW, 2016) |
| "Hypertension is a global health concern for which novel treatment strategies are necessary." | ( Iranpour, D; Louis, XL; Movahed, A; Netticadan, T; Ostovar, A; Raj, P; Smoliga, JM; Thandapilly, SJ, 2016) |
| "Type 2 diabetes and hypertension are associated with cognitive dysfunction that includes pathological changes in brain tissue." | ( Blumenthal-Katzir, T; Grigoriadis, N; Hollander, K; Lagoudakic, R; Rosenthal, T; Touloumi, O; Younis, FM, 2016) |
| "Chronic hypertension is the most critical risk factor for cardiovascular disease, heart failure, and stroke." | ( Ait-Aissa, K; Belmadani, S; Gabani, M; Haddox, S; Irani, K; Kassan, M; Mali, V; Matrougui, K; Radwan, E; Trebak, M; Zhang, W, 2016) |
| "Hypertension is associated with impaired nitric oxide (NO)-cyclic nucleotide (CN)-coupled intracellular calcium (Ca(2+)) homeostasis that enhances cardiac sympathetic neurotransmission." | ( Bardsley, EN; Larsen, HE; Lefkimmiatis, K; Paterson, DJ, 2016) |
| "The risk of hypertension is increased by intrauterine growth restriction (IUGR) and preterm birth." | ( Roghair, R; Steinbrekera, B, 2016) |
| "Hypertension is a major risk factor for many cardiovascular diseases and leads to subsequent concomitant pathologies such as left ventricular hypertrophy (LVH)." | ( Baldus, S; Eickholt, C; Jungen, C; Klatt, N; Kuklik, P; Lau, D; Meyer, C; Muellerleile, K; Reitmeier, A; Schad, C; Schäffer, B; Scherschel, K; Schwedhelm, E; Steven, D; Wassilew, K; Willems, S; Yamamura, J; Zeller, T, 2016) |
| "Hypertension is the prime risk factor for stroke, and primary aldosteronism (PA) is the most common cause of secondary hypertension." | ( Joki, H; Kamide, T; Kawabata, Y; Kitamura, Y; Minami, T; Miyaji, Y; Mori, K; Nakaguchi, H; Nomura, M; Sasaki, M; Seki, S; Shima, H; Tamase, A; Tanaka, F; Tsunoda, T; Yamada, M, 2016) |
| "Isolated systolic hypertension is the most common hemodynamic form of hypertension in the elderly." | ( Bavishi, C; Goel, S; Messerli, FH, 2016) |
| "Hypertension is a key risk factor for heart failure, with the latter characterized by diaphragm muscle weakness that is mediated in part by increased oxidative stress." | ( Adams, V; Bowen, TS; Drobner, J; Eisenkolb, S; Fischer, T; Linke, A; Mangner, N; Schuler, G; Werner, S, 2017) |
| "Hypertension is currently one of the greatest global health care challenges." | ( Barho, C; Gottwald-Hostalek, U; Hildemann, S; Sun, N, 2017) |
| "Hypertension is a major risk factor for ischemic heart disease and stroke, leading causes of morbidity and death worldwide." | ( Abrams, SA; Guzman-Bárcenas, J; Hawthorne, KM; Henriksen, T; Jiménez-Estrada, I; Landers, S; Muñoz, O; Petersson, M; Schanler, RJ; Uvnäs-Moberg, K; Vargas-Martínez, F, 2017) |
| "Hypertension is a common problem in elderly cats." | ( Bijsmans, ES; Doig, M; Elliott, J; Jepson, RE; Pelligand, L; Syme, HM, 2016) |
| "Hypertension is the leading risk factor contributing to mortality worldwide, primarily from cardiovascular disease (CVD), while effective treatment of hypertension is proven to reduce CVD events." | ( Hughes, CF; McNulty, H; Strain, JJ; Ward, M, 2017) |
| "Hypertension is the most important, modifiable risk factor for cardiovascular disease and mortality." | ( Dalili, N; Jamalian, A; Samadian, F, 2016) |
| "Hypertension is one of the most common conditions seen in primary care and a major public health problem in India." | ( Shete, MM, 2016) |
| "Resistant hypertension is associated with increased risk for cardiovascular events." | ( Andersson, B; Li-Ming, G; Rundqvist, B; Svedlund, S; Völz, S, 2017) |
| "Uncontrolled hypertension is a major problem in India." | ( Bharatia, R; Chitale, M; Dalvi, K; Kumar, RG; Saxena, GN; Talele, S; Trailokya, A, 2016) |
| "Hypertension is considered to be the most important risk factor for stroke, and all forms of hypertension are associated with an increased risk of both ischemic and haemorrhagic stroke." | ( Muruganathan, A; Tiwaskar, M, 2016) |
| "Hypertension is the most important cause of global burden of disease." | ( Gupta, R; Khedar, RS; Panwar, RB, 2016) |
| "Hypertension is associated with alterations in the vascular structure, which in turn enhance the risk of cardiovascular events." | ( Parati, G, 2016) |
| "Resistant hypertension is a common clinical situation." | ( Holaj, R; Petrák, O; Rosa, J; Štrauch, B; Widimský, J; Zelinka, T, 2016) |
| "Hypertension is a common comorbidity in patients with T2DM, and is associated with excess morbidity and mortality." | ( Reed, JW, 2016) |
| "Once hypertension is established, increased mechanical stretch stress becomes a leading cause of vascular remodeling." | ( Bardeesi, ASA; Deng, L; Guo, Y; Li, C; Li, Y; Li, Z; Liu, K; Liu, S; Pei, T; Ping, S; Sheng, P; Wang, H; Wang, J; Zhou, Y, 2017) |
| "Hypertension is a leading risk factor for dementia, but the mechanisms underlying its damaging effects on the brain are poorly understood." | ( Anrather, J; Chang, H; Faraco, G; Garcia-Bonilla, L; Iadecola, C; Lane, D; Murphy, M; Racchumi, G; Santisteban, MM; Sugiyama, Y; Van Rooijen, N, 2016) |
| "Hypertension is associated with increased reactive oxygen species (ROS) production in the paraventricular nucleus (PVN) of the hypothalamus." | ( Guo, J; Hou, C; Huo, C; Kang, Y; Li, H; Liu, J; Miao, Y; Sun, W; Wang, M; Wang, X; Yang, L, 2017) |
| "Hypertension is emerging in rural populations of India." | ( Alim, M; Arabshahi, S; Chow, C; D'Esposito, F; Evans, RG; Guggilla, RK; Joshi, R; Kalyanram, K; Kartik, K; Mahal, A; Maulik, PK; Mini, GK; Oldenburg, B; Riddell, MA; Sathish, T; Srikanth, VK; Suresh, O; Thankappan, KR; Thomas, N; Thrift, AG; Varma, RP, 2016) |
| "Hypertension is a main risk factor for the development of cerebral small vessel disease (cSVD) - a major contributor to stroke and the most common cause of vascular dementia." | ( Meissner, A; Minnerup, J; Planas, AM; Soria, G, 2017) |
| "Hypertension is one of the most important cardiovascular risk factors and results in macrophage infiltration of blood vessels." | ( Iwao, H; Izumi, Y; Miura, K; Nishiyama, M; Osada-Oka, M; Sakurai, E; Shiota, M; Tanaka, M; Yamaguchi, T, 2017) |
| "Hypertension is the leading risk factor causing mortality and morbidity worldwide." | ( Chu, PL; Le, TH; Rump, LC; Stegbauer, J; Yang, G, 2017) |
| "Hypertension is an important risk factor for premature death as it increases the probability of stroke, myocardial infarction, and heart failure." | ( Antza, C; Kotsis, V; Stabouli, S, 2016) |
| "Hypertension is a major risk factor for cardiovascular diseases." | ( Daliri, EB; Lee, BH; Oh, DH, 2017) |
| "Primary hypertension is characterized by Na excess and K deficit in the body, which together are key to its pathogenesis." | ( Adrogué, HJ; Madias, NE, 2017) |
| "Prehypertension is associated with higher cardiovascular risk, target organ damage, and incidence of hypertension." | ( Alves, JG; Berwanger, O; Bordignon, A; Brandão, AA; Castro, I; Cesarino, EJ; Chaves, H; Consolim-Colombo, FM; de Alencastro, PR; de Mello, RB; de Sousa, MR; Figueiredo Neto, JA; Franco, RS; Fuchs, FC; Fuchs, FD; Fuchs, SC; Gus, M; Jardim, PC; Moreira, LB; Mosele, F; Mota Gomes, M; Neto, AA; Nobre, F; Nóbrega, AC; Poli-de-Figueiredo, CE; Scala, LC; Schlatter, R; Silva, RP; Sobral Filho, DC; Steffens, AA; Vilela-Martin, JF; Whelton, PK, 2016) |
| "Nocturnal hypertension is particularly prevalent in OSA and is a strong predictor of cardiovascular mortality." | ( Arima, H; Cistulli, PA; Grunstein, RR; Phillips, CL; Serinel, Y; Wong, KH; Yee, BJ, 2017) |
| "Hypertension is the most common disease affecting humans and imparts a significant cardiovascular and renal risk to patients." | ( Hsu, R; Lawless, S; Lee, A; Samson, R; Sander, G, 2017) |
| "Hypertension is a major risk factor for cardiovascular and cerebrovascular disease." | ( Deng, Y; Guo, J; Huang, Y; Li, L; Li, X; Pu, X; Wang, J; Wei, Y; Yi, P; Yin, N; Yu, J; Zheng, Y, 2016) |
| "Hypertension is the leading risk factor for cardiovascular diseases." | ( Blanco-Garcia, C; Mendez, M; Mukherjee, D; Wani-Parekh, P, 2017) |
| "Salt-sensitive hypertension is associated with renal and vascular dysfunctions, which lead to impaired fluid excretion, increased cardiac output, and total peripheral resistance." | ( Pavlov, TS; Staruschenko, A, 2017) |
| "Hypertension is a major risk factor contributing to cardiovascular disease, which is the number one cause of deaths worldwide." | ( Carlson, DJ; Dieberg, G; Inder, J; McFarlane, JR; Palanisamy, SKA; Smart, NA, 2016) |
| "Hypertension is the leading cause of cardiovascular disease worldwide." | ( de Vries, C; Haerden, Y; Lins, R, 2017) |
| "Hypertension is a major public health problem worldwide and a key factor for chronic kidney disease (CKD)." | ( Ahmed, E; Ejaz, M; Hatcher, J; Jaffar, T; Mubarak, M, 2017) |
| "Hypertension is the most common cause of cardiovascular morbidities and mortalities, and a major risk factor for renal dysfunction." | ( Dugbartey, GJ, 2017) |
| "Hypertension is a very common pathology, and its clinical treatment largely relies on different drugs." | ( Guala, A; Leone, D; Milan, A; Ridolfi, L, 2017) |
| "Hypertension is a complex condition involving functional and structural alterations of the microvasculature and an activation of the immune system." | ( Jiménez-Altayó, F; Jurado, A; Meissner, A; Miro, F; Planas, AM; Vila, E, 2017) |
| "Hypertension is considered an immunologic disorder." | ( Abboud, FM; Chapleau, MW; Cicha, MZ; Irani, K; Kumar, S; Meyerholz, DK; Singh, MV, 2017) |
| "One way to control hypertension is inactivation of the Renin- Angiotensin- Aldosterone System (RAAS)." | ( Ranjbar, B; Taghdir, M; Tavassoli, Z, 2018) |
| "Hypertension is an important risk factor for adverse cardiovascular events." | ( Jones, PJ; Loader, TB; Taylor, CG; Zahradka, P, 2017) |
| "Hypertension is one of the leading risk factors for morbidity and mortality in patients with cardiovascular and cerebrovascular diseases and renal impairment." | ( Coats, A; Jain, S, 2017) |
| "Hypertension is a complex disease explained with diverse factors including environmental factors and genetic factors." | ( Kim, J; Kim, K; Kwock, CK; Park, YM; Yang, YJ, 2017) |
| "Hypertension is one of the most common problems encountered in the primary care setting." | ( Church, KS; Foster, CA; Poddar, M; Spaic, T; Van Uum, SH, 2017) |
| "Resistant hypertension is defined as an uncontrolled blood pressure despite treatment at best-tolerated doses with at least three antihypertensive agents including a diuretic." | ( Constantine, GR; Galappatthy, P; Katulanda, P; Rajapakse, S; Ranasinghe, P; Senarath, U; Weeraratne, C; Weeratunga, P, 2017) |
| "Hypertension is associated with unfavorable changes in adrenergic receptor responsiveness, but the relationship of race and sex to adrenergic receptor responsiveness in the development of cardiovascular disease is unclear." | ( Blumenthal, JA; Hill, LK; Hinderliter, AL; Johnson, KS; Sherwood, A, 2017) |
| "Hypertension is a multifactorial disease." | ( Al-Gassimi, S; Biancardi, VC; Bomfim, GF; Nunes, KP; Reis, WL, 2017) |
| "Hypertension is a leading cause of morbidity and mortality worldwide." | ( Castro, MM; Pinheiro, LC; Tanus-Santos, JE, 2017) |
| "Hypertension is one of the most common diseases in humans, and there is a special concern on the consequences of maternal hypertensive conditions for the health of newborns." | ( Amstislavskaya, TG; Amstislavsky, SY; Brusentsev, EY; Igonina, TN; Petrova, OM; Ragaeva, DS; Rozkova, IN; Tikhonova, MA, 2017) |
| "Hypertension is one of the most important, preventable causes of premature morbidity and mortality in the developed world." | ( Du, N; Du, Y; Gu, H; Kowala, MC; Ma, Z; Shatara, A; Wang, J; Yi, X; Zhu, T, 2017) |
| "Hypertension is a multifaceted disease that is involved in ∼40% of cardiovascular mortalities and is the result of both genetic and environmental factors." | ( Basting, T; Lazartigues, E, 2017) |
| "Up-to-date, hypertension is the most significant contributing factor to CVDs." | ( Aboul Wafa, OM; Fahmy, H; Farghaly, AM; Fronczek, FR; Teleb, M; Zamponi, GW; Zhang, FX, 2017) |
| "Hypertension is a major cause of heart failure." | ( Fujii, K; Ide, T; Ikeda, M; Kishi, T; Nishikawa, T; Oga, Y; Sakamoto, T; Saku, K; Sunagawa, K; Tohyama, T; Tsutsui, H, 2017) |
| "Hypertension is a dominating risk factor for cardiovascular disease." | ( Albinsson, S; Bakker, ENTP; Bavel, EV; Krawczyk, KK; Rippe, C; Sjölund, J; Swärd, K; Zhu, B, 2017) |
| "Neurogenic hypertension is characterized by an increase in sympathetic activity and often resistance to drug treatments." | ( Culicchia, F; Domenig, O; Lazartigues, E; Moreno-Walton, L; Poglitsch, M; Sriramula, S; Xia, H; Xu, J, 2017) |
| "Hypertension is an increased risk of heart failure and acute myocardial infarction (MI)." | ( Li, P; Liu, N; Peng, QS; Ping, S; Shi, WD; Zhou, NQ, 2017) |
| "Obesity-associated hypertension is accompanied by a number of cardiovascular risk factors including vascular insulin resistance (IR) and higher sympathetic nervous activity." | ( Brum, PC; Carneiro, EM; da Silva Franco, N; Davel, AP; Guizoni, DM; Lubaczeuski, C; Santos-Silva, JC; Victorio, JA, 2017) |
| "Hypertension is associated with enhanced vascular oxidative stress and impaired endothelial function, which is related to an imbalance between reactive oxygen species and nitric oxide bioavailability." | ( Croft, KD; Del Pino-García, R; González-SanJosé, ML; Muñiz, P; Rivero-Pérez, MD, 2017) |
| "When hypertension is uncontrolled by routine treatment with an angiotensin II receptor blocker (ARB) and the calcium channel blocker amlodipine (5 mg), the dose of amlodipine can be increased or a diuretic can be added." | ( Okamura, K; Okuda, T; Shirai, K; Totake, N; Urata, H, 2018) |
| "Refractory hypertension is a recently described phenotype of antihypertensive treatment failure defined as uncontrolled blood pressure (BP) despite the use of ≥5 different antihypertensive agents, including chlorthalidone and spironolactone." | ( Calhoun, DA; Judd, EK; Oparil, S; Siddiqui, M, 2017) |
| "Hypertension is the major risk factor for stroke." | ( Bernstein, KE; Fang, J; Johnson, AK; Li, L; Li, Y; Lyden, P; Shen, XZ; Shi, P; Zhao, TV, 2017) |
| "Women with chronic hypertension are at significant risk for maternal and fetal morbidity and mortality, yet it remains unclear whether antihypertensive treatment during pregnancy lowers these risks." | ( August, P; Podymow, T, 2017) |
| "Hypertension is influenced by traditional risk factors and duration of HIV infection but not antiretroviral treatment." | ( Grzeszczuk, A; Janczarek, M; Kocbach, P; Kowalczuk-Kot, A; Leszczyszyn-Pynka, M; Rogalska-Płońska, M; Rogalski, P; Stempkowska, J, 2017) |
| "Uncontrolled hypertension is an important contributor to cardiovascular disease." | ( Crooke, RM; Engelhardt, JA; Graham, MJ; Mullick, AE; Prakash, TP; Yeh, ST, 2017) |
| "Hypertension is a global health issue and is currently increasing at rapid pace in South Asian countries including Bangladesh." | ( Ahmed, S; Al Nahid, A; Ali, N; Khanum, FA; Mahmood, S; Manirujjaman, M; Perveen, R; Rahman, M, 2017) |
| "Although hypertension is associated with worse cognitive function, behavioural symptoms and hippocampal glucose hypometabolism, it is not associated with evidence of increased amyloid or tau pathology." | ( Moonga, I; Niccolini, F; Pagano, G; Politis, M; Wilson, H, 2017) |
| "Hypertension is a well-established risk factor for adverse cardiovascular events, and older age is a risk factor for the development of hypertension." | ( Armesilla, AL; Austin, C; Cartwright, EJ; Hammad, SK; Kurusamy, S; Little, R; Neyses, L; Nguyen, L; Njegic, A; Prehar, S; Zi, M, 2017) |
| "Hypertension is an important risk factor for adverse cardiovascular events including stroke, myocardial infarction, heart failure and renal failure." | ( Gueyffier, F; Musini, VM; Puil, L; Salzwedel, DM; Wright, JM, 2017) |
| "Hypertension is one of the leading risk factors for cardiovascular, cerebrovascular, and renal disease." | ( Paradkar, SG; Sinha, SR, 2018) |
| "Arterial hypertension is a highly manageable disorder due to a variety of drugs available for its treatment." | ( DeObeso-Gonzalez, E; Flores-Villalba, E; Lammel-Lindemann, JA; Martagón, AJ; Puente-Gallegos, F, 2018) |
| "Hypertension is one of the primary modifiable risk factors for cardiovascular disease." | ( El-Ashmony, SM; Fatani, SH; Kamel, HF; Shamardl, HA, 2017) |
| "Hypertension is one of the major risk factors for central nervous system (CNS) disorders like stroke and Alzheimer's disease (AD)." | ( Bhat, SA; Goel, R; Hanif, K; Shukla, R; Shukla, S, 2018) |
| "Hypertension is a chronic and debilitating disease." | ( Akhter, QS; Akhter, S; Banu, N; Mahmuda, S; Nahar, S; Yeasmin, N; Yeasmin, S, 2017) |
| "Hypertension is the most common risk factor for stroke, coronary heart disease and heart failure, which are the leading causes of death worldwide." | ( Bobak, Ł; Martynowicz, H; Nowacki, D; Skoczyńska, A; Szuba, A; Trziszka, T; Turczyn, B; Wojakowska, A, 2017) |
| "Subjects with hypertension are frequently obese or insulin resistant, both conditions in which hyperuricemia is common." | ( Johnson, RJ; Kelly, J; MacGinley, RJ; Major, TJ; Merriman, TR; Todd, AS; Walker, RJ, 2017) |
| "Hypertension is a highly prevalent co-morbidity in HIV patients." | ( Chepchirchir, A; Jaoko, W; Nyagol, J, 2018) |
| "Systolic hypertension is common in elderly patients and remains a challenge to treat effectively." | ( Hafeez, K; Rakugi, H; Supasyndh, O; Wang, J; Zhang, J; Zhang, Y, 2017) |
| "Essential hypertension is mainly caused by endothelial dysfunction which results from nitric oxide (NO) deficiency." | ( Aboubakar, BFO; Bilanda, DC; Dimo, T; Dzeufiet, PDD; Kamtchouing, P; Kouakep, L; Tedong, L, 2017) |
| "Hypertension is one of the leading causes of morbidity and mortality in Ethiopia." | ( Alemayehu, C; Aseffa, A; Clavarino, A; McGree, J; Mitchell, G; Nikles, J, 2017) |
| "Hypertension is associated with significant cardiovascular morbidity and mortality." | ( Chlabicz, S; Gryko, A; Głowińska-Olszewska, B; Milewski, R; Owłasiuk, A; Płudowska, K; Smithson, WH; Wojtkielewicz, K; Żelazowska-Rutkowska, B, 2017) |
| "Family history of hypertension is correlated with higher values of systolic blood pressure and higher values of parameters for carbohydrate metabolism in children." | ( Chlabicz, S; Gryko, A; Głowińska-Olszewska, B; Milewski, R; Owłasiuk, A; Płudowska, K; Smithson, WH; Wojtkielewicz, K; Żelazowska-Rutkowska, B, 2017) |
| "Morning hypertension is an independent risk for cerebrovascular and cardiovascular events." | ( Anegawa, T; Fukuda, K; Fukumoto, Y; Imaizumi, T; Iwamoto, Y; Kai, H; Kajimoto, H; Uchiwa, H, 2018) |
| "The prevalence of hypertension is very common amongst the diabetic patients and is reported as the major cause of mortality in diabetes." | ( Chatterjee, B; Pal, TK; Sengupta, P, 2017) |
| "Hypertension is a systemic disorder that affects numerous physiological processes throughout the body." | ( Cong, X; Liu, LM; Wang, Y; Wu, LL; Xiang, RL; Yu, GY; Zhang, J; Zhang, Y; Zhong, LJ, 2017) |
| "Hypertension is associated with endothelial dysfunction, which favors the release of endothelium-derived contracting factors, including vasoconstrictor prostanoids and reactive oxygen species." | ( Chen, H; Leung, SWS; Man, RYK, 2018) |
| "Post-transplant hypertension is a common occurrence during treatment with calcineurin inhibitors (CNIs) in kidney transplant population." | ( Bonfante, L; Calò, LA; Furian, L; Marchini, F; Naso, E; Ravarotto, V; Rigotti, P; Simioni, F, 2017) |
| "Resistant hypertension is a common clinical problem in South Africa and is frequently associated with low renin and aldosterone levels, especially in black Africans." | ( Ensor, J; Freercks, R; Jones, E; Meldau, S; Rayner, B; Weimers-Willard, C, 2017) |
| "Hypertension is an important risk factor for cardiovascular disease." | ( Chang, CC; Chen, LK; Huang, PH; Lin, SJ; Liu, LK; Tsai, YL, 2018) |
| "Hypertension is considered a lifestyle disease." | ( Kasacka, I; Nowińska, P, 2017) |
| "Hypertension is the major risk factor for cardiovascular diseases and is one of the primary causes of morbidity and mortality worldwide." | ( Asvadi Fard, M; Babaee Bigi, MA; Ghardashi Afousi, A; Izadi, MR, 2018) |
| "Arterial hypertension is associated with altered levels of blood borne hormones." | ( Grabska-Liberek, I; Przybek, J; Skrzypecki, J; Ufnal, M, 2018) |
| "Hypertension is a common but frequently overlooked adverse effect of erythropoietin (EPO) therapy." | ( Agarwal, R, 2018) |
| "Hypertension is characterized by vascular wall remodeling, endothelial dysfunction, and immune infiltration." | ( Caillon, A; Delneste, Y; Favre, J; Guihot, AL; Henrion, D; Kauffenstein, G; Martin, L; Merot, J; Nascimento, DC; Robson, SC; Roy, C; Ryffel, B; Sévigny, J; Tabiasco, J, 2018) |
| "Resistant hypertension is a major health concern with unknown cause." | ( Barrett, E; Bayliss, DA; Butcher, JT; Chiu, YH; DeLalio, LJ; Desai, BN; Good, ME; Isakson, BE; Jaffe, IZ; Leitinger, N; Lohman, AW; Lorenz, UM; Medina, CB; Mendu, SK; Poon, IKH; Ravichandran, KS, 2018) |
| "Hypertension is highly prevalent in patients with rheumatoid arthritis (RA)." | ( Carranza-Leon, D; Chung, CP; Michael Stein, C; Octaria, R; Oeser, A; Okafor, CR; Ormseth, MJ; Solus, JF; Titze, J; Zhang, Y, 2018) |
| "Hypertension is frequently associated with metabolic disorders." | ( Cai, X; Lian, G; Lin, Z; Wang, T; Xie, L, 2018) |
| "Hypertension is a metabolic disease which is caused by vasoconstriction and that results into elevated blood pressure." | ( Chatterjee, M; Ghosh, TK; Jana, P; Karmakar, S; Maji, UK; Saha, A, 2018) |
| "Hypertension is prevalent in chronic kidney disease (CKD)." | ( Andrew, R; Freel, EM; Homer, NZM; Jardine, AG; Mark, PB; McQuarrie, EP; Rankin, AJ; Taylor, AHM, 2018) |
| "Essential hypertension is a multifactorial disorder with a strong genetic predisposition." | ( Clark, MA; Haspula, D, 2018) |
| "Hypertension is an important health problem that is manifested by systemic arterial blood pressure being permanently elevated and leading to serious complications." | ( Acar, N; Keles-Celik, N; Sekerci, R; Tepekoy, F; Ustunel, I, 2018) |
| "Hypertension is attributable to the modifiable factors like risky lifestyle practices." | ( Bhise, MD; Patra, S, 2018) |
| "Hypertension is the leading modifiable risk factor for death worldwide, yet the causes remain unclear and treatment remains suboptimal." | ( Collister, JP; Fiege, J; Foss, JD; Mayerhofer, T; Osborn, JW; Shimizu, Y; Wood, L, 2018) |
| "Resistant hypertension is characterized when the blood pressure (BP) remains above the recommended goal after taking three antihypertensive drugs with synergistic actions at their maximum recommended tolerated doses, preferably including a diuretic." | ( Cestário, EDES; Cosenso-Martin, LN; Fernandes, LAB; Giollo-Júnior, LT; Landim, MIP; Matarucco, CSS; Moreno, H; Tácito, LHB; Uyemura, JRR; Vilela-Martin, JF; Yugar-Toledo, JC, 2018) |
| "Hypertension is associated with renal infiltration of activated immune cells; however, the role of renal lymphatics and immune cell exfiltration is unknown." | ( Abouelkheir, GR; Balasubbramanian, D; Hudson, KR; Johnson, ER; Lopez Gelston, CA; Lopez, AH; Mitchell, BM; Muthuchamy, M; Rutkowski, JM, 2018) |
| "Hypertension is becoming a global epidemic for both rural and urban populations; it is a major public health challenge in Iran." | ( Hooshmand, E; Jalilzadeh, M; Mahvi, AH; Mohammadi, AA; Nabizadeh, R; Yaseri, M; Yousefi, M, 2018) |
| "Hypertension is a generally accepted atherogenic risk factor." | ( Li, L; Liu, J; Wang, H; Zhao, H; Zhao, XX; Zhou, Y, 2019) |
| "Hypertension is not a typical feature of steroid sensitive nephrotic syndrome (SSNS) and the presence of persistent hypertension is suggestive of significant renal lesion." | ( Aggrawal, KC; Agrawal, N; Bansal, S; Guilliani, BP; Keshri, S; Sharma, S, 2018) |
| "Arterial hypertension is a disease that still affects a major part of the population worldwide, and leads to fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions." | ( Athanasiadi, E; Katsi, V; Tousoulis, D; Tsioufis, C, 2018) |
| "Hypertension is a health issue affecting adolescents." | ( Cheah, WL; Grace Kho, WF; Hazmi, H, 2018) |
| "As hypertension is a major risk factor of morbidity and mortality worldwide, much attention has been paid to the blood pressure reducing effect of inorganic nitrate." | ( Carlström, M; Lundberg, JO; Weitzberg, E, 2018) |
| "Resistant hypertension is defined as a lack of ambulatory blood pressure response to optimized medical treatment after exclusion of secondary hypertension in patients who are fully adherent to antihypertensive therapy." | ( Huang, QF; Staessen, JA; Wei, FF; Zhang, ZY, 2018) |
| "Hypertension is one of the most prevalent diseases worldwide and can cause harmful complications within the vascular system." | ( Ando, M; Iguchi, M; Kobayashi, S; Kobayashi, T; Matsumoto, T; Taguchi, K, 2018) |
| "Hypertension is a major risk factor for cardiovascular disease, a leading cause of premature death and disability in India." | ( Abdel-All, M; Chow, CK; Evans, RG; Guggilla, R; Joshi, R; Kalyanram, K; Kartik, K; Mahal, A; Maulik, PK; Mini, GK; Oldenburg, B; Riddell, M; Suresh, O; Thankappan, KRT; Thomas, N; Thrift, AG, 2018) |
| "Ethnicity and hypertension are predictive of gout risk, and the associations cannot be fully explained by serum urate." | ( Gaffo, AL; Los Campos, G; Merriman, TR; Reeves, M; Reynolds, RJ; Singh, JA; Sun, M; Vazquez, AI, 2018) |
| "Hypertension is a serious component of metabolic syndrome (MetS)." | ( Bassossy, HME; Fahmy, A; Hassan, NA; Mahmoud, MF, 2018) |
| "Hypertension is a major global public health issue." | ( Guo, L; Li, D; Li, H; Liu, G; Peng, T; Shi, W; Wang, Y; Xie, T; Yang, H; Yang, X; Zhen, J, 2018) |
| "Hypertension is an important public health challenge because of its high prevalence and strong association with cardiovascular disease and premature death." | ( Bakker, SJL; de Borst, MH; Joosten, MM; Schutten, JC, 2018) |
| "Hypertension is a critical risk factor for the development of ischemic stroke." | ( Hsieh, YS; Kwon, S; Lee, HS; Seol, GH, 2018) |
| "Neonatal hypertension is increasingly recognized as dramatic improvements in neonatal intensive care, advancements in our understanding of neonatal physiology, and implementation of new therapies have led to improved survival of premature infants." | ( Flynn, JT; Starr, MC, 2019) |
| "Hypertension is the leading cause of death worldwide." | ( Akyazi, I; Erkasap, N; Kus, G; Kutlay, O; Ozkurt, M; Ozyurt, R; Uysal, O; Uzuner, K, 2018) |
| "Hypertension is central in determining cardiovascular risk and is a strong predictive indicator of morbidity and mortality; however, there remains an unmet clinical need for disease-modifying and prophylactic interventions." | ( Ajijola, OA; Ardell, JL; Bardsley, EN; Buckler, KJ; Davis, H; Paterson, DJ; Shivkumar, K, 2018) |
| "Hypertension is a global health problem, and angiotensin I (ANG I)-converting enzyme (ACE) inhibitors are largely used to control this pathology." | ( Andrade, MCC; Campanha-Rodrigues, AL; Casarini, DE; Costa-Neto, CM; Mortara, RA; Nogueira, MD; Parreiras-E-Silva, LT; Pereira, LM; Reis, RI, 2018) |
| "Uncontrolled hypertension is a primary risk factor for diverse cardiovascular diseases and thus remains responsible for significant morbidity and mortality." | ( Humphrey, JD; Latorre, M, 2018) |
| "Uncontrolled hypertension is frequently the cause of cardiovascular complications." | ( Bruno, G; Iannaccone, A; Maffei, I; Milan, A; Ravera, A; Schiavone, D; Veglio, F, 2019) |
| "Hypertension is strongly associated with chronic diseases such as myocardial infarction, stroke, heart failure, and renal failure." | ( Ab Majid, NL; Abd Hamid, HA; Khoo, YY; Ling Miaw Yn, J; Mahadir Naidu, B; Mat Rifin, H; Mohd Yusoff, MF; Omar, MA; Robert Lourdes, TG; Rodzlan Hasani, WS, 2018) |
| "Hypertension is an important risk factor for death resulting from stroke, myocardial infarction, and end-stage renal failure." | ( Hashimoto, K; Ichihara, M; Iwamoto, T; Kato, K; Matsuoka, H; Miyata, S; Nagahara, M; Noda, A; Okumura, N; Sobue, S; Takeda, K; Watanabe, T, 2019) |
| "A reduced risk of hypertension is observed in metformin users in a dose-response pattern." | ( Tseng, CH, 2018) |
| "Diabetes and hypertension are two leading non-communicable conditions, which are suboptimally managed in India." | ( Ghosh, S; Gupta, R; Jarhyan, P; Kalra, S; Malhotra, C; Mohan, S; Prabhakaran, D; Rana, R; Rao, MB; Srinath Reddy, K; Tandon, N; Venkateshmurthy, NS, 2018) |
| "Arterial hypertension is associated with autonomic nervous system dysfunction." | ( Antunes, VR; Falquetto, B; Marina, N; Moreira, TS, 2018) |
| "Hypertension is a leading contributor to the global burden of disease." | ( Balabanova, D; Candari, CJ; Dans, AL; Idris, K; Ismail, JR; Krauss, SE; Lasco, G; Majid, FA; McKee, M; Palafox, B; Palileo-Villanueva, LM; Razak, AA; Renedo, A; Seguin, ML; Yusoff, K, 2018) |
| "Intradialytic hypertension is estimated at 5-15% of hemodialysis patients and is associated with poor prognosis." | ( Angeloudi, E; Balaskas, I; Bikos, A; Kalaitzidis, R; Karpetas, A; Liakopoulos, V; Loutradis, C; Panagoutsos, S; Papagianni, A; Pasadakis, P; Raptis, V; Sarafidis, PA, 2019) |
| "Primary hypertension is a major risk factor for ischemic heart disease, stroke, and chronic kidney disease." | ( Abo-Zahrah, R; Bertin, T; Bissig, KD; Bryan, NS; Burrage, LC; Chen, S; Devaraj, S; Erez, A; Jiang, H; Jiang, MM; Jin, Z; Kho, J; Kim, JJ; Lee, BH; Ma, S; Nagamani, SCS; Reddy, AK; Rodney, GG; Shchelochkov, OA; Tian, X; Wong, WT; Zhang, P, 2018) |
| "Hypertension is usually associated with deficient nitric oxide (NO) bioavailability, and therefore stimulating NO activity is an important antihypertensive strategy." | ( Oliveira-Paula, GH; Tanus-Santos, JE, 2019) |
| "Hypertension is particularly prevalent in African countries, though the majority of studies have focused on mainland Africa." | ( Bloomfield, GS; Guidera, LN; Leonard, AS; Manus, MB; Nunn, CL; Samson, DR, 2018) |
| "Hypertension is described as increased blood pressure based on changed hemodynamics and associated with an increased oxidative damage to reproductive function." | ( Gulhan, MF, 2019) |
| "Poorly controlled hypertension is a leading global public health problem requiring new treatment strategies." | ( Amarasekara, S; Amarasena, N; Billot, L; de Silva, AP; de Silva, HA; Fernando, M; Guggilla, R; Jan, S; Jayawardena, J; Maulik, PK; Mendis, S; Munasinghe, J; Naik, N; Patel, A; Prabhakaran, D; Rajapakse, S; Ranasinghe, G; Rodgers, A; Salam, A; Selak, V; Senaratne, V; Stepien, S; Thom, S; Tisserra, N; Webster, R; Wijekoon, S; Wijeyasingam, S, 2018) |
| "Chronic hypertension is a multifactorial disease that is highly associated with cardiovascular disorders." | ( Chen, CW; Chen, SA; Hsu, WH; Hu, YF; Kuo, TBJ; Li, JY; Lin, SF; Sung, YL; Syu, JY; Weng, CH; Wu, CE, 2018) |
| "Hypertension is one of the silent killers in the world with high mortality and morbidity." | ( Adedapo, AA; Adejumobi, OA; Afolabi, JM; Ajibade, TO; Arojojoye, OA; Asenuga, ER; Falayi, OO; Hassan, FO; Ochigbo, GO; Ogunpolu, BS; Ola-Davies, OE; Omobowale, TO; Oyagbemi, AA; Saba, AB; Yakubu, MA, 2018) |
| "Hypertension is a leading risk factor for cardiovascular and chronic kidney disease." | ( Clark, BJ; Hannah, AR; Leader, CJ; Sammut, IA; Walker, RJ; Wilkins, GT, 2018) |
| "Hypertension is the most important modifiable risk factor for stroke and is associated with poorer post-stroke outcomes." | ( Chamorro, Á; Dantas, AP; Jiménez-Altayó, F; Jiménez-Xarrié, E; Martí-Fabregas, J; Pérez, B; Planas, AM; Puertas-Umbert, L; Vila, E, 2020) |
| "Hypertension is the most important risk factor for chronic disease burden in India." | ( Gaur, K; Gupta, R; S Ram, CV, 2019) |
| "The Precision HYpertenSIon Care (PHYSIC) study aims to investigate if there is a consistent between-person variation in blood pressure response to the common blood pressure-lowering drug classes of a clinically relevant magnitude, given the within-person variation in blood pressure." | ( Ekman, I; Lind, L; Lytsy, P; Marttala, K; Nowrouzi, S; Öhagen, P; Östlund, O; Sundström, J, 2019) |
| "Hypertension is associated with major cardiovascular (CV) and renal complications." | ( Amara, VR; Surapaneni, SK; Tikoo, K, 2019) |
| "Hypertension is the most common chronic disease, and most important risk factor for cardiovascular disease." | ( Li, H; Ren, Y; Wu, Y; Zhao, X, 2018) |
| "Although hypertension is considered a chronic inflammatory disease, the molecular basis of the sterile inflammatory response involved in hypertension remains unclear." | ( Boini, KM; Chen, Y; Huang, Y; Lai, J; Lian, D; Wang, L; Wu, Y; Zhang, Y, 2018) |
| "Hypertension is a major cause of left ventricular (LV) diastolic dysfunction." | ( Bamaiyi, AJ; Mojiminiyi, FB; Norman, G; Norton, GR; Peterson, V; Woodiwiss, AJ, 2018) |
| "Hypertension is a multifactorial disease with limited knowledge of the involved mechanisms." | ( Calhau, C; Faria, A; Pestana, D; Sá, C, 2018) |
| "Hypertension is a civilization disease leading to remodeling and damage of blood vessels, impaired renal function and premature death." | ( Dobrzyńska, I; Figaszewski, ZA; Skrzydlewska, E; Szachowicz-Petelska, B; Weresa, J, 2019) |
| "Hypertension is a growing global epidemic." | ( Hsu, CN; Tain, YL, 2018) |
| "Acute severe hypertension is a common problem among inner-city ethnic minority populations." | ( Afshartous, D; Arciniegas, R; Bernstein, J; DeGraff, S; Materson, BJ; Preston, RA, 2019) |
| "A history of hypertension is a known risk factor for delirium in patients in intensive care units, but the effect of antihypertensive agents on delirium development is unclear." | ( Chuma, M; Goda, M; Hamano, H; Horinouchi, Y; Imai, T; Imanishi, M; Ishizawa, K; Kayano, M; Kitamura, Y; Kondo, Y; Kouno, Y; Koyama, T; Mitsui, M; Niimura, T; Okada, N; Sendo, T; Takechi, K; Ujike, Y; Yanagawa, H; Zamami, Y, 2018) |
| "It is proved that hypertension is a common CVD complication and a major death risk factor as well as contributes for decline in a renal function." | ( Kaminski, TW; Karbowska, M; Mor, AL; Mysliwiec, M; Pawlak, D; Pawlak, K; Znorko, B, 2019) |
| "Hypertension is the primary risk factor for cardiovascular disease that constitutes a serious worldwide health concern and a significant healthcare burden." | ( Chappell, MC; Diz, DI; Hendricks, AS; Shaltout, HA; South, AM; Washburn, LK, 2019) |
| "BACKGROUND Hypertension is a leading global disease, and myocardial fibrosis is an important adverse effect of hypertension, seriously threatening human health." | ( Fang, T; Guo, B; Wang, L; Xue, L, 2019) |
| "Hypertension is an enormous public-health challenge in the world due to its high prevalence and consequent increased cardiovascular disease morbidity and mortality." | ( Dolan, J; He, J; Liu, Y; Shi, M, 2020) |
| "Depression and hypertension are medical problems both with clearly restricted pharmacotherapies, along with a high prevalence around the world." | ( Bergantin, LB, 2020) |
| "Hypertension is common." | ( Bailey, MA; Baudrie, V; Costello, HM; Czopek, A; Dhaun, N; Farrah, T; Guyonnet, L; Kluth, DC; Lenoir, O; Menolascina, F; Moorhouse, R; Owen, E; Tharaux, PL; van Bragt, J; Webb, DJ, 2019) |
| "Hypertension is a multifactorial disease, manifested by vascular dysfunction, increased superoxide production, and perivascular inflammation." | ( Graham, D; Guzik, TJ; Justo-Junior, AS; Kiss, AK; Kowalczyk, P; Koziol, J; Kusmierczyk, Z; Luc, K; Maffia, P; Mazur, M; Mikolajczyk, TP; Naruszewicz, M; Nosalski, R; Schramm-Luc, A; Skiba, DS, 2019) |
| "Hypertension is a common comorbidity in patients with heart failure and most drugs that have demonstrated to improve prognosis in this population have the potential to reduce blood pressure." | ( Pinho-Gomes, AC; Rahimi, K, 2019) |
| "Hypertension is one of the most common chronic diseases." | ( Irzmański, R; Kapusta, J; Kidawa, M; Kowalski, J; Rynkowska-Kidawa, M, 2018) |
| "Hypertension is considered the major modifiable risk factor for the development of cognitive impairment." | ( Don-Doncow, N; Meissner, A; Vanherle, L; Zhang, Y, 2019) |
| "Hypertension is a multifactorial disease associated with impaired nitric oxide (NO) production and bioavailability." | ( Oliveira-Paula, GH; Pinheiro, LC; Tanus-Santos, JE, 2019) |
| "Hypertension is the chronic medical condition and it affected billions of people worldwide." | ( Jaiswal, V; Khan, A; Khan, H; Kulshreshtha, S, 2019) |
| "Orthostatic hypertension is associated with future mortality risk, is easily detected, and can be used in refining cardiovascular risk assessment." | ( Cabrera, J; Cosgrove, NM; Cushman, WC; Davis, BR; Kostis, JB; Kostis, WJ; Mekkaoui, C; Moreyra, AE; Pantazopoulos, JS; Pressel, SL; Sargsyan, D; Sedjro, JE, 2019) |
| "Hypertension is an important risk factor that causes many deaths in the world every year." | ( Ghorbanzadeh, H; Mashhadi, FD; Salari, R, 2020) |
| "The occurrence of hypertension is influenced by combined actions of genetic and environmental factors." | ( Li, Y; Mu, J; Sun, N, 2019) |
| "Hypertension is a leading cause of cardiovascular and chronic renal disease." | ( Komnenov, D; Levanovich, PE; Rossi, NF, 2019) |
| "Hypertension is associated with increased risk of morbidity and mortality in adults." | ( Remington, J; Winters, K, 2019) |
| "Hypertension is more common in males while obesity and inadequate physical activity is more common in females." | ( Avasthi, A; Dua, D; Jain, S; Sharma, A; Shouan, A; Singh, SM; Surendran, I, 2019) |
| "Hypertension is a major health concern in the developed world, and its prevalence increases with advancing age." | ( Alexander, GE; Barnes, CA; Biwer, LA; Chawla, MK; Coleman, PD; De Both, M; Fitzhugh, MC; Hale, TM; Hoang, LT; Huentelman, M; Mitchell, KD; Trouard, TP; Uprety, AR; Willeman, MN; Zempare, MA, 2019) |
| "Refractory hypertension is defined as uncontrolled blood pressure despite use of ≥5 antihypertensive agents of different classes, including a long-acting thiazide-like diuretic and an MR (mineralocorticoid receptor) antagonist, at maximal or maximally tolerated doses." | ( Acelajado, MC; Calhoun, DA; Hughes, ZH; Oparil, S, 2019) |
| "Background Hypertension is a known risk factor for heart failure ( HF ), possibly via the mechanism of cardiac remodeling and left ventricular hypertrophy ( LVH )." | ( Davis, BR; Johnson, K; Oparil, S; Tereshchenko, LG, 2019) |
| "Pregnancy hypertension is common in less-developed settings." | ( Adetoro, OO; Bellad, MB; Bhutta, ZA; Goudar, S; Lee, T; Macuacua, SE; Magee, LA; Mallapur, A; Nathan, HL; Payne, BA; Qureshi, R; Sevene, E; Sharma, S; Shennan, AH; Sotunsa, J; Valá, A; Vidler, M; von Dadelszen, P, 2019) |
| "Hypertension is one of the major causes of mortality." | ( Shin, HM; Tettey, CO; Yang, IJ, 2019) |
| "Diabetes and hypertension are the two major causes of chronic kidney disease (CKD)." | ( Habib, A; Hussain, S; Najmi, AK, 2019) |
| "Hypertension is a major cause of death and morbidity worldwide and is increasing in prevalence." | ( Li, N; Ma, R; Yu, J; Yu, X; Zhao, X; Zhao, Y, 2019) |
| "Hypertension is considered as the most common risk factor for cardiovascular disease." | ( Barrows, IR; Raj, DS; Ramezani, A, 2019) |
| "Pregnancy-induced hypertension is a major cause of maternal and fetal morbidity and mortality." | ( Jim, B; Reddy, S, 2019) |
| "Hypertension is one of the most important risk factors and a leading cause of death from cardiovascular and cerebrovascular diseases." | ( Murakami, K; Takimoto-Ohnishi, E, 2019) |
| "High salt-induced hypertension is relevant to the levels of pro-inflammatory cytokines (PICs) and oxidative stress in the hypothalamic paraventricular nucleus (PVN)." | ( Chen, YM; Cui, W; Fu, LY; Gao, HL; Kang, KB; Kang, YM; Liang, YF; Liu, KL; Qi, J; Shi, XL; Xin, GR; Yu, XJ; Zhang, DD, 2019) |
| "Hypertension is the leading risk factor for global mortality and morbidity and remains the major preventable cause of cardiovascular diseases." | ( Chen, LX; Ma, Z; Song, JJ; Wang, J; Zhong, JC, 2020) |
| "Hypertension is the most important noncommunicable disease risk factor in India with an estimated burden of 200 million persons." | ( Gupta, R; Ram, CVS, 2019) |
| "Hypertension is more common in developed states of the country, urban populations and better socioeconomic status individuals." | ( Gupta, R; Ram, CVS, 2019) |
| "Hypertension is widely prevalent in India with large regional variation, greater prevalence in urban areas and the young." | ( Gupta, R; Ram, CVS, 2019) |
| "Background Hypertension is common among patients with Alzheimer disease." | ( Claassen, JAHR; de Heus, RAA; Donders, R; Lawlor, BA; Olde Rikkert, MGM; Santoso, AMM, 2019) |
| "Hypertension is the most dangerous factor linked to deaths caused by cardiovascular diseases." | ( Cai, Q; Huang, J; Li, D; Wan, X; Wang, R; Xie, Z; Yang, CS, 2019) |
| "Hypertension is a major independent risk factor for cardiovascular disease, stroke and renal failure; thus, elucidation of the etiopathology of hypertension merits further research." | ( Cerecedo, D; De la Mora-Mojica, B; Durán-Álvarez, C; García-Rubio, D; Martínez-Vieyra, V; Méndez-Méndez, J; Rodríguez-Varela, M, 2019) |
| "Hypertension is defined as systolic blood pressure ≥ 140 mm Hg or diastolic blood pressure ≥ 90 mm Hg, or taking antihypertensive medication." | ( Cao, J; Cui, Y; Guo, H; Huo, Y; Jiang, C; Li, J; Li, Y; Lin, T; Ling, W; Liu, C; Liu, L; Qin, X; Song, Y; Tang, G; Wang, B; Wang, X; Xu, X; Yang, J; Yang, Y; Zhang, H; Zhang, J; Zhang, Y; Zhou, Z, 2019) |
| "Hypertension is a common chronic disease, and it is the strongest risk factor for cardiovascular disease." | ( Lan, F; Liu, M; Peng, XD; Sun, JC; Tan, X; Wang, R; Wang, WZ; Wang, YK; Wu, Q; Xia, DM, 2019) |
| "Hypertension is a primary risk factor for cardiovascular diseases including myocardial infarction and stroke." | ( Albarrán-Juárez, J; Chen, M; Dancs, PT; Fleming, I; Graumann, J; Günther, S; Iring, A; Jin, YJ; Künne, C; Martínez, A; Nakayama, A; Offermanns, S; Siragusa, M; Sokol, AM; Tonack, S; Wang, S; Weinstein, LS; Wettschureck, N, 2019) |
| "Hypertension is now viewed as a disorder of blood vessels and treatment is directed at the vasculature rather than the blood pressure, with the latter currently serving as a biomarker for arterial injury." | ( Epstein, MR; Lazar, JM; Monaghan, TF; Weiss, JP, 2019) |
| "Intra-abdominal hypertension is known as a factor affecting cerebral haemodynamics." | ( Ardasheva, RG; Dobrev, HP; Kristev, AD; Turiyski, VI; Vassilev, PG, 2019) |
| "Hypertension is one of the major causes of chronic diseases." | ( Cho, SJ; Kim, HS; Lee, JW; Park, B; Park, EA; Park, H, 2019) |
| "Since hypertension is the most important cerebrovascular risk factor in populations prone to mild brain trauma, we induced mTBI in normotensive Wistar and spontaneously hypertensive rats (SHR) and we assessed BBB permeability, extravasation of blood-borne substances, neuroinflammation and cognitive function two weeks after trauma." | ( Amrein, K; Bali, ZK; Buki, A; Czeiter, E; Czigler, A; Hernadi, I; Kellermayer, Z; Koller, A; Szarka, N; Tadepalli, SA; Toth, L; Toth, P; Ungvari, Z; Wahr, M, 2019) |
| "Hypertension is one of the strongest risk factors for stroke in the general population, while systolic blood pressure has been shown to independently increase the risk of stroke in type 1 diabetes." | ( Dahlström, EH; Forsblom, CM; Groop, PH; Hägg-Holmberg, S; Harjutsalo, V; Liebkind, R; Putaala, J; Tatlisumak, T; Thorn, LM, 2019) |
| "Systemic hypertension is a major risk factor for the development of cardiovascular disease and is often associated with endothelial dysfunction." | ( Braun, AP; Kendrick, DJ; Khaddaj Mallat, R; Mathew John, C; Mishra, RC, 2019) |
| "Essential hypertension is the leading preventable cause of death in the world." | ( Baccarelli, AA; Barretta, F; Bollati, V; Ferrari, L; Guazzi, M; Sironi, S; Tarantini, L; Vicenzi, M, 2019) |
| "Hypertension is a risk factor for both stroke and bleeding in patients with atrial fibrillation." | ( Antman, EM; Bergmark, BA; Braunwald, E; Chung, N; Giugliano, RP; Lanz, HJ; Park, S; Ruff, CT; Shi, M, 2019) |
| "Hypertension is a common clinical problem, and increased aldosterone is the most prevalent underlying characteristic." | ( Geng, X; Hou, X; Li, L; Xu, Y, 2020) |
| "Obesity and hypertension are prevalent comorbidities in heart failure with preserved ejection fraction." | ( Brandt, MM; Cheng, C; Cramer, MJ; Duncker, DJ; Joles, JA; Krebber, MM; Mokry, M; Nguyen, ITN; van de Wouw, J; Verhaar, MC, 2019) |
| "Hypertension is considered a major public health issue due to its high prevalence and subsequent risk of cardiovascular and kidney diseases." | ( Bába, L; Boda, F; Ferencz, E; Péterfi, O; Szabó, Z, 2019) |
| "For instance, hypertension is found in 36-41% gout patients, and combined with metabolic syndrome it may reach 80%." | ( Bychkov, ОА; Bychkova, NG; Bychkova, SA; Kondratiuk, VE; Morozova, ZV; Tarasiuk, AP, 2019) |
| "Hypertension is a multifactorial disorder with serious complications and unknown etiology." | ( Evangelopoulos, ME; Evangelopoulou, A; Mavragani, CP; Sereti, E; Stamatelopoulos, KS; Zakopoulos, NA, 2020) |
| "Hypertension is common in peritoneal dialysis (PD) patients and associated with adverse outcomes." | ( Davenport, A; Vongsanim, S, 2020) |
| "Hypertension is a global public issue, and sleep status was regarded as its risk factor; however, the results were inconsistent." | ( Chen, J; Chen, WZ; Han, B; Li, YC; Zeng, ZQ, 2020) |
| "Hypertension is a global disease that has been combating the world health for ages." | ( Adejumobi, OA; Aluko, EO; Fasanmade, AA, 2019) |
| "Hypertension is associated with increased sympathetic activity." | ( de Morais, SDB; Gao, L; Shanks, J; Wang, HJ; Zucker, IH, 2019) |
| "Hypertension is the most commonly reported comorbidity among cancer patients." | ( Kozłowska, K; Kozłowski, L; Małyszko, J, 2019) |
| "Hypertension is the leading cause of cardiovascular disease globally." | ( Attaran, A; Bangdiwala, SI; Camacho, PA; Islam, S; Lamelas, P; Lopez-Jaramillo, P; Majid, F; McCready, T; McKee, M; Schwalm, JD; Thabane, L; Yusoff, K; Yusuf, S, 2019) |
| "Hypertension is one of the most common chronic diseases and an increasingly public-health challenge worldwide." | ( Chen, G; Luo, X; Shao, K; Wang, J; Yu, H; Zhang, Y, 2019) |
| "System hypertension is a major risk factor for cardiac hypertrophy and heart failure." | ( Chen, C; Fang, J; Geng, C; Guo, SB; Li, HH; Li, PB; Liu, Y; Yan, X; Yang, J; Zhang, YL; Zou, LX, 2019) |
| "Alcohol-related hypertension is in the causal pathway between alcohol use and increased risk for several cardiovascular outcomes." | ( Barden, AE; Beilin, LJ; Mori, TA; Puddey, IB, 2019) |
| "Hypertension is the most common modifiable risk factor for stroke, and understanding the underlying mechanisms of hypertension and hypertension-related stroke is crucial." | ( Booz, GW; Fan, F; Fan, L; Li, M; Roman, RJ; Shekhar, S; Varghese, K, 2019) |
| "Hypertension is one of the most common AEs related to MKI treatment." | ( Budolfsen, C; Bæk Møller, N; E Magnusson, N; Grimm, D; Infanger, M; Krüger, M; Wehland, M, 2019) |
| "Hypertension is associated with enzalutamide in the treatment of prostate cancer." | ( Wu, S; Zhu, X, 2019) |
| "Hypertension is one of the most challenging health problems in the world." | ( Agarwal, S; Aggarwal, A; Dabadghao, VS; Khese, VB; Malik, SK; Sharma, SK, 2019) |
| "Hypertension is a significant public health problem." | ( Bertelli, M; Dallavilla, T; Guerri, G; Krasi, G; Marinelli, C; Perrone, M; Precone, V; Romeo, F; Stuppia, L; Zulian, A, 2019) |
| "Hypertension is a complex syndrome of multiple hemodynamic, neuroendocrine, and metabolic abnormalities." | ( Dineva, S; Filipova, E; Kalinov, K; Pavlova, V; Uzunova, K; Vekov, T, 2019) |
| "Hypertension is one of the main causes of premature death in the world; also, it is associated with several bone alterations." | ( Antoniali, C; Faverani, LP; Mulinari-Santos, G; Okamoto, R; Palin, LP; Santos, JSD; Silva, ACED, 2019) |
| "Obesity-related hypertension is a common disorder, and attempts to combat the underlying obesity are often unsuccessful." | ( Banerjee, S; Chambliss, KL; Chu, H; Kifer, D; Lauc, G; Mineo, C; Peng, J; Polasek, O; Rohatgi, A; Sacharidou, A; Shaul, PW; Sundgren, NC; Tanigaki, K; Vongpatanasin, W; Yuhanna, IS, 2019) |
| "Hypertension is a risk factor for erectile dysfunction (ED) and both conditions are associated with oxidative stress." | ( Carneiro, FS; da Silva, CBP; do Vale, GT; Gonzaga, NA; Leite, LN; Pinheiro, LC; Tanus-Santos, JE; Tirapelli, CR, 2020) |
| "Hypertension is a chronic condition that can lead to several health problems, such as cardiovascular diseases, myocardial infarction, stroke, retinopathy and renal failure." | ( Ghaedi, E; Hadi, A; Pourmasoumi, M; Sahebkar, A, 2019) |
| "Resistant hypertension is a common clinical entity, defined as suboptimal blood pressure response to multiple therapies after excluding medication nonadherence and secondary forms of hypertension." | ( Gubbi, S; Hannah-Shmouni, F; Koch, CA; Spence, JD; Stratakis, CA, 2019) |
| "Hypertension is a health problem of global priority." | ( Datta, S; Niranjjan, R; Roy, G; Sahu, SK, 2019) |
| "Arterial hypertension is a condition associated with endothelial dysfunction, accompanied by an imbalance in the production of reactive oxygen species (ROS) and NO." | ( Aires, R; Campagnaro, BP; Campos-Toimil, M; Leal, MAS; Marques, VB; Meyrelles, SS; Pandolfi, T; Pereira, TMC; Vasquez, EC, 2020) |
| "Hypertension is common in the general population." | ( Bachmann, S; Mutig, K, 2019) |
| "Hypertension is highly prevalent in India but frequency of resistant hypertension has not been well studied." | ( Gupta, N; Gupta, R; Khedar, RS; Sharma, KK; Soni, S, 2019) |
| "Obesity-related hypertension is one of the world's leading causes of death and yet little is understood as to how it develops." | ( Baylie, RA; Csato, V; Eisner, DA; Greenstein, AS; Kadir, SZAS; Nelson, MT; Sugden, SA, 2020) |
| "Hypertension is present in more than 50% of patients with type 2 diabetes mellitus." | ( Fukui, M; Hamaguchi, M; Iwai, K; Kitae, A; Kitagawa, N; Oyabu, C; Shiraishi, M; Ushigome, E; Ushigome, H; Yamazaki, M; Yokota, I, 2019) |
| "Hypertension is associated with gut dysbiosis." | ( Algieri, F; de la Visitación, N; Duarte, J; Gálvez, J; Gómez-Guzmán, M; Jiménez, R; Muñoz, R; Redondo, JM; Robles-Vera, I; Romero, M; Sánchez, M; Toral, M; Vezza, T, 2020) |
| "Hypertension is a common cardiovascular disease in clinical scenario." | ( Chang, F; Gao, R; Huangfu, W; Wang, M, 2019) |
| "Perioperative hypertension is a common occurrence in the neurosurgical population, where 60% to 90% of the patients require treatment for blood pressure (BP) control." | ( Bergese, SD; Borrell-Vega, J; Palettas, M; Uribe, AA, 2020) |
| "Hypertension is highly prevalent in Black Africans and has been found to be associated with worse blood pressure (BP) control and more cardiovascular disease." | ( Jones, E; Rayner, B, 2021) |
| "Worldwide, hypertension is an important public health challenge because of its high prevalence and the concomitant risks of cardiovascular disease." | ( Huang, L; Jing, R; Li, L; Li, R; Liu, L; Qiao, J; Shi, H; Sun, R; Yang, D; Zhu, C, 2020) |
| "Hypertension is associated with renal immune cell accumulation and sodium retention." | ( Balasubbramanian, D; Baranwal, G; Clark, MC; Goodlett, BL; Mitchell, BM; Rutkowski, JM, 2020) |
| "Resistant hypertension is diagnosed if the blood pressure (BP) is not controlled despite optimum doses of 3 first-line classes of antihypertensive drugs including a thiazide diuretic or if adequate BP control needs 4 or more antihypertensive drugs from different classes." | ( Aronow, WS, 2020) |
| "Background Hypertension is a cardiovascular disease which has become a major health problem in Indonesia." | ( Hasmono, D; Hijriani, N; Yusetyani, L, 2020) |
| "Hypertension is a long-term medical condition in which the blood pressure is gradually elevated." | ( Esfahani, Z; Javadi, H; Mehdi Mirhashemi, S; Reza Memarzadeh, M; Yaghoobzadeh, H, 2019) |
| "Hypertension is a major risk factor for cardiovascular and cerebrovascular disease." | ( Annad, U; Balaraju, B; Bandaru, VS; Chaudhuri, JR; Kuchulakanti, PK; Samala, NR; Tallapaneni, L, 2020) |
| "Hypertension is a major cardiovascular illness worldwide with many underlying causes." | ( Bastola, MM; Fontelo, P; Locatis, C; Maisiak, R, 2020) |
| "Hypertension is one of the most common cardiovascular diseases in the world and is associated with oxidative stress." | ( Dobrzyńska, I; Figaszewski, ZA; Pędzińska-Betiuk, A; Skrzydlewska, E; Szachowicz-Petelska, B, 2020) |
| "Nocturnal hypertension is clinically important for patients with type 2 diabetes (T2D), considering its strong correlation with cardiovascular events." | ( Aoki, S; Atsumi, T; Cho, KY; Kameda, R; Kawata, S; Kurihara, Y; Miyoshi, H; Nagai, S; Nakamura, A; Nomoto, H; Omori, K; Takeuchi, J, 2020) |
| "Hypertension is a major public health problem among the aging population worldwide." | ( Aono, T; Arimoto, T; Goto, J; Kato, S; Kutsuzawa, D; Narumi, T; Nishiyama, S; Otaki, Y; Shishido, T; Sugai, T; Takahashi, H; Takahashi, T; Tamura, H; Toshima, T; Wanezaki, M; Watanabe, K; Watanabe, M; Watanabe, T, 2020) |
| "Hypertension is a complication of obstructive sleep apnea (OSA) syndrome in adults." | ( Amin, R; Brooks, DM; Brooks, LJ; Chng, SY; Dougherty, S; Gallagher, PR; Guo, R; Kelly, A; Koren, D; Marcus, CL; Sorkin, JD, 2020) |
| "Background Hypertension is a silent killer with no obvious signs and symptoms; thus, it is crucial to prevent its development." | ( Mahlakata, F; Nkeh-Chungag, BN; Oyedeji, OO; Sewani-Rusike, CR; Shauli, M; Tata, CM, 2020) |
| "Hypertension is commonly a quiet condition, and it expands the risk of heart diseases and stroke." | ( Chaudhari, SR; Shirkhedkar, AA, 2021) |
| "Essential hypertension is a prevalence chronic cardiovascular disease, which is treated by traditional Chinese medicine (TCM) in China." | ( Cong, H; Dong, H; Du, W; Zhang, L; Zhang, S, 2020) |
| "Global incidence of hypertension is estimated to be, in excess of, one billion people, and given the efficacy of soluble dietary fibers, in particular, Psyllium, to positively impact blood pressure in patients with hypertension, it is of clinical importance that consensus on its supplementation be established." | ( Aghabagheri, E; Clark, CCT; Jafarnejad, S; Salek, M, 2020) |
| "Hypertension is an important risk factor for cardiovascular diseases." | ( Bal, NB; Demirel-Yilmaz, E; Han, S; Kiremitci, S; Uludag, MO, 2020) |
| "Arterial hypertension is a major public health problem in sub-Saharan Africa due to its high frequency and to the cardiovascular risk that it entails." | ( Cissé, BM; de la Barca, JMC; Dembélé, KC; Denis, MC; Diakité, M; Diarra, MB; Dramé, BSI; Goïta, Y; Homedan, C; Joubaud, F; Kassogué, Y; Keita, A; Mirebeau-Prunier, D; Reynier, P; Simard, G, 2020) |
| "Hypertension is considered as a multifactorial disorder in which a numerous of physiological mechanism take part to raise blood pressure The present study is carried out to study the serum and red blood cell electrolytes disturbances in men and women patients of essential hypertension." | ( Samad, N; Yasmin, F, 2020) |
| "Essential hypertension is a significant risk factor for cardiovascular disease, renal disease, and mortality with increasing prevalence." | ( Buus, NH; Grimm, D; Krüger, M; Simonsen, U; Wehland, M, 2020) |
| "Hypertension is a major contributing factor to cardiovascular disease and is a leading cause of death in the world." | ( Ali, N; Haque, T; Islam, S; Kathak, RR; Rahman, S, 2020) |
| "Chronic hypertension is associated with adverse perinatal outcomes, although the optimal treatment is unclear." | ( Bellos, I; Daskalakis, G; Loutradis, D; Papapanagiotou, A; Pergialiotis, V, 2020) |
| "Hypertension is an important global public health problem." | ( Carreón-Torres, E; Castrejón-Téllez, V; Díaz-Díaz, E; Guarner-Lans, V; Pérez-Torres, I; Rubio-Ruiz, ME; Villegas-Romero, M, 2020) |
| "Hypertension is a diverse illness interlinked with cerebral, cardiovascular (CVS) and renal abnormalities." | ( Kumar, BRP; Kumar, HY; Murthy, NBS; Ramya, K; Suresh, R, 2020) |
| "Hypertension is an important cardiovascular disease, which need long-term medication." | ( Chen, B; Guo, M; Jin, C; Li, J; Peng, X; Song, X; Yang, J; Yu, T; Zeng, J; Zhang, Y; Zhao, S, 2020) |
| "Hypertension is an independent and preventable risk factor for the development of cardiovascular diseases, however, little is known about the impact of gut microbiota composition in its development." | ( Artacho, A; Calderón-Pérez, L; Companys, J; Gosalbes, MJ; Jimenez-Hernandez, N; Llauradó, E; Ludwig, I; Pedret, A; Pla-Pagà, L; Romero, MP; Rubió, L; Solà, R; Valls, RM; Yuste, S, 2020) |
| "Among them, hypertension is a leading cause for stroke, heart disease and kidney failure." | ( Batthyany, C; Bresque, M; Caggiani, M; Calliari, A; Colman, L; Contreras, P; Escande, C; Leyva, A; Liechocki, S; Maya-Monteiro, CM; Mazal, D, 2020) |
| "The causes of hypertension are complex and involve both genetic and environmental factors." | ( Byrne, CJ; Khaper, N; Khurana, S; Lamothe, J; Mercier, S; Tai, TC; Tharmalingam, S; Williamson, C, 2020) |
| "Hypertension is the most common risk factor for cardiovascular disease, causing over 18 million deaths a year." | ( Abdelbary, M; Baban, B; Belanger, KM; Brands, MW; Crislip, GR; Elmarakby, A; Gillis, EE; Mohamed, R; Musall, JB; Sullivan, JC, 2020) |
| "Essential hypertension is a major risk factor for cardiovascular disease that can lead eventually to structural and functional alterations in the brain." | ( Hou, Q; Jiang, H; Li, Y; Yang, W; Yu, R; Zhang, D, 2020) |
| "Hypertension is characteristically associated with vascular dysfunction, cardiovascular remodelling, renal dysfunction, and stimulation of the sympathetic nervous system." | ( Alves-Lopes, R; Camargo, LL; Montezano, AC; Neves, KB; Rios, FJ; Touyz, RM, 2020) |
| "Hypertension is the leading cause for the development of heart failure (HF)." | ( Engström, G; Fernandez, C; Melander, O; Nilsson, J; Orho-Melander, M; Ruskoaho, H; Rysä, J; Ström, K, 2020) |
| "Salt-sensitive (SS) hypertension is accompanied by impaired vasodilation in the systemic and renal circulation." | ( Agbor, LN; Fang, S; Grobe, JL; McCormick, JA; Morgan, DA; Mukohda, M; Nair, AR; Nakagawa, P; Rahmouni, K; Sharma, A; Sigmund, CD; Weiss, RM; Wu, J, 2021) |
| "Hypertension is a major public health problem of adult population across the globe that significantly increases the risk of heart attack, stroke, kidney failure and blindness." | ( Akter, N; Dipa, MI; Firoz, S; Islam, MF; Israt, S; Nessa, A; Rahman, HH; Sharmin, A, 2020) |
| "Hypertension is a condition in which blood pressure is elevated to an extent where benefit is obtained from blood pressure lowering." | ( Kavitha, J; Kokilambigai, KS; Lakshmi, KS; Sai Susmitha, A; Seetharaman, R, 2021) |
| "Systemic arterial hypertension is a public health problem associated with an increased risk of cardiovascular disease." | ( Amaral, JH; Bonacio, GF; Dellalibera-Joviliano, R; Franca, SC; Garcia, VT; Mattos, BR; Rizzi, E; Tanus-Santos, JE; Vitorino, TR, 2020) |
| "Hypertension is a common chronic disease and poses a huge burden to health care systems." | ( Fang, Z; Li, Y; Qian, L; Wang, Y; Wu, L; Yan, S; Zheng, Y, 2020) |
| "Hypertension is accompanied by oxidative stress, which can be modified by the functioning of the endocannabinoid system playing a prominent modulatory role in the brain." | ( Baranowska-Kuczko, M; Biernacki, M; Niklińska, GN; Skrzydlewska, E, 2020) |
| "Hypertension is common in black populations and is known to be associated with low nitric oxide (NO) bioavailability." | ( Bollenbach, A; Craig, A; Kruger, R; Mels, CMC; Schutte, AE; Schwedhelm, E; Tsikas, D, 2021) |
| "Women with chronic hypertension are an easily recognized group who are in touch with a wide variety of healthcare providers before, during, and after pregnancy, mandating that chronic hypertension in pregnancy be within the scope of many practitioners." | ( Kametas, N; Khalil, A; Magee, LA; von Dadelszen, P, 2022) |
| "Hypertension is a major risk factor for cardiovascular disease globally." | ( Talukdar, D; Teelucksingh, S; Tripathi, M; Tripathi, V, 2021) |
| "Hypertension is affected by both genetic and dietary factors." | ( Jeong, H; Jin, HS; Kim, SS; Shin, D, 2020) |
| "Hypertension is a public health concern that needs immediate attention upon diagnosis." | ( Badr, H; Elkafrawy, N; Kamal Zewain, S; Kamel, M; M El-Desoky, A; Mohamed, S; Naguib, A; Raoof, GFA; Younes, K, 2020) |
| "Non-dipper hypertension is prevalent in young and middle-aged adults; but the optimal antihypertensive strategy remains unclear." | ( Liu, J, 2020) |
| "Hypertension is a prevalent disease characterized by autonomic-induced elevated and sustained blood pressure levels and abnormal body core temperature (Tb) regulation." | ( Alberici, LC; Amorim, MR; Branco, LGS; de Deus, JL; Ferrari, GD; Moreira, DA; Nogueira, JE; Santos, BM, 2020) |
| "The incidence of hypertension is on the rise in India, and effective and sustainable interventions are needed." | ( Garner, SL; George, CE; Green, G; Hitchcock, J; Koch, H; Mahid, Z; Norman, G; Young, P, 2020) |
| "Hypertension is a highly prevalent disease marked by vascular and cardiac maladaptive remodelling induced mainly by renin-angiotensin system activation followed by oxidative stress." | ( Batista, RIM; Guimaraes, DA; Tanus-Santos, JE, 2021) |
| "Adequate control of hypertension is a global challenge and is the key to reduce cardiovascular disease risk factors." | ( Husin, M; Khamis, N; Lim, MT; Sivasampu, S; Teh, XR; Tong, SF, 2020) |
| "Hypertension is a known risk factor for stroke and low cardiac output in patients requiring mechanical circulatory support and a narrow therapeutic window of blood pressure is often targeted." | ( Jahadi, O; Kwiatkowski, DM; Moss, J; Rosenthal, DN; Ryan, KR; Wu, M, 2020) |
| "Hypertension is not uncommon in patients living with HIV." | ( Gebrie, A, 2020) |
| "Hypertension is a disease with significant clinical and socio-economic consequences." | ( Dineva, S; Filipova, E; Kalinov, K; Pavlova, V; Uzunova, K; Vekov, T, 2020) |
| "Malignant arterial hypertension is a clinical syndrome characterized by severe diastolic arterial hypertension with signs of ischemic damage to target organs - kidneys, heart, brain, eyes." | ( Kozlovskaya, NL; Krasnolutskaya, EI; Sheludchenko, VM; Smirnova, TV, 2020) |
| "Hypertension is one of the leading risk factors for cardiovascular diseases in India and Nepal." | ( Abe, SK; Nomura, S; Rahman, MM; Rahman, MS; Rauniyar, SK; Shibuya, K, 2020) |
| "Hypertension is a chronic condition leading to increased stress on the heart and blood vessels, a critical risk factor for clinically significant events such as myocardial infarction heart failure, stroke and death." | ( Dineva, S; Filipova, E; Kalinov, K; Pavlova, V; Uzunova, K; Vekov, T, 2021) |
| "Hypertension is one of the most important risk factors for cardiovascular diseases." | ( Ariaratnam, S; Ghazali, SS; Ho, BK; Krishnapillai, A; Majid, NLBA; Omar, MA; Sooryanarayana, R; Tohit, NM; Yusof, MFBM; Zainal Abidin, SBI, 2020) |
| "Hypertension is the most important risk factor for RVO." | ( Binder, H; Closs, EI; Gericke, A; Habermeier, A; Pfeiffer, N; Ponto, KA; Rosner, AK; Scharrer, I, 2021) |
| "Hypertension is one of the leading causes of cardiovascular mortality and morbidity." | ( Bhat, A; Dasari, D; Dhar, A; Goyal, SG; Jadhav, KB; Kalra, J; Mangali, S, 2020) |
| "systemic hypertension is a foremost risk factor for cardiovascular morbidity and mortality." | ( Adebayo, RA; Adewuya, OA; Ajayi, EA; Ojo, OE; Olaoye, OB, 2020) |
| "Hypertension is the biggest contributor to global burden of disease and mortality." | ( Chaudhary, G; Joseph, S; Konda Reddy, KM; Murthy, LS; Nikam, P; Rajarshi, M; Sawhney, JP; Shah, S; Thacker, H, 2020) |
| "Hypertension is one of the critical risk factors of cerebrovascular disease." | ( Ding, M; Guo, S; Lao, M; Li, L; Wang, Q; Xu, Z, 2020) |
| "The treatment for hypertension is particularly challenging in people undergoing dialysis." | ( Esterhuizen, TM; Mugendi, GA; Mutua, FM; Natale, P; Strippoli, GF, 2020) |
| "Hypertension is defined as the persistence of elevated blood pressure in the circulation system." | ( Ahemad, N; Goh, BH; Khan, SU; Looi, D; Palanisamy, UD, 2021) |
| "Hypertension is one of the major risk factors for arteriosclerosis." | ( Ohinata, K; Shobako, N, 2020) |
| "Hypertension is the most common cardiovascular disease that affects approximately 26% of adult population, worldwide." | ( Adedapo, AA; Adejumobi, OA; Ajani, OS; Ajibade, TO; Aro, AO; Bolaji-Alabi, FB; Emikpe, BO; Jarikre, TA; Kayoka-Kabongo, PN; McGaw, LJ; Nkadimeng, SM; Oguntibeju, OO; Ola-Davies, OE; Omobowale, TO; Oyagbemi, AA; Oyeyemi, MO; Saba, AB; Soetan, KO; Yakubu, MA, 2020) |
| "Hypertension is a major risk factor for cerebrovascular disease." | ( Gao, W; Liu, C; Liu, X; Liu, Y; Luo, C; Man, S, 2021) |
| "Hypertension is a growing clinical problem in pediatric population." | ( Dmitrzak-Węglarz, M; Neyman-Bartkowiak, A; Nowicki, M; Ostalska-Nowicka, D; Paszyńska, E; Rabiega, A; Zachwieja, J, 2021) |
| "Hypertension is associated with oxidative stress and perivascular inflammation, critical contributors to perivascular fibrosis and accelerated vascular ageing." | ( Guzik, TJ; Koziol, J; Maffia, P; Mikolajczyk, T; Nosalski, R; Saju, B; Siedlinski, M, 2020) |
| "Nocturnal hypertension is an important phenotype of abnormal diurnal blood pressure (BP) variability and a known risk marker for target organ damage and cardiovascular events." | ( Ito, S; Itoh, H; Kario, K; Okuda, Y; Rakugi, H; Yamakawa, S; Yoshimura, M, 2021) |
| "Hypertension is the most important cause of death and disability in the elderly." | ( Anastasi, E; Baumbach, J; De Mey, JGR; Elbatreek, MH; Guney, E; Hassan, AA; Hsu, CY; Huang, PH; Janssen, GM; Kacprowski, T; Kleikers, PWM; Nogales, C; Sadegh, S; Schiffers, PMH; Schmidt, HHHW; Teubner, A; Wipat, A, 2020) |
| "Hypertension is a risk factor of atrial fibrillation (AF), and a certain number of patients with hypertension were found with an enlarged left atrium." | ( An, X; Liu, Y; Liu, YJ; Lv, H; Niu, XH; Tan, R; Xia, YL; Yang, X; Yin, X, 2020) |
| "Hypertension is one of the dangerous health conditions prevalent in society, is a risk factor for several other diseases if left untreated and anti-hypertensives (AHs) are the approved drugs to treat it." | ( Sharma, R, 2020) |
| "Hypertension is the the primary cause of diastolic heart failure." | ( Guan, X; Lu, C; Meng, Y; Shang, B; Zhang, Z; Zhao, Y, 2020) |
| "Hypertension is often characterised by impaired vasodilation involving dysfunction of multiple vasodilatory mechanisms." | ( Bercea, CI; Cottrell, GS; McNeish, AJ; Tamagnini, F, 2021) |
| "Hypertension is an important risk factor for nonalcoholic steatohepatitis." | ( Asano, T; Hashimoto, S; Kitamori, K; Naito, H; Nakajima, T; Yuan, Y, 2020) |
| "Hypertension is a common condition that increases risk for future cardiovascular disease." | ( Arora, P; Cushman, M; Judd, SE; Long, DL; McClure, LA; Nicoli, CD; Plante, TB, 2021) |
| "Hypertension is a complex condition in which various actors and mechanisms combine, resulting in cardiovascular and cerebrovascular complications that today represent the most frequent causes of mortality, morbidity, disability, and health expenses worldwide." | ( Barbagallo, M; Dominguez, L; Veronese, N, 2020) |
| "Hypertension is an important worldwide public-health challenge because of its high frequency and concomitant risks of cardiovascular and kidney disease." | ( Akter, N; Dipa, MI; Firoz, S; Islam, MF; Israt, S; Nessa, A; Noor, F; Rahman, MH; Sharmin, A; Yeasmin, F, 2021) |
| "Hypertension is a complex disease and is the major cause of cardiovascular complications." | ( Bachi, A; Capasso, G; Lanzani, C; Manunta, P; Matafora, V; Simonini, M; Trepiccione, F; Zacchia, M; Zagato, L, 2021) |
| "While hypertension is an important contributor to cardiovascular disease (CVD) and its treatment has well-established mortality benefits, there is uncertainty as regards the management of isolated systolic hypertension (ISH)." | ( Ioannou, P; Papadakis, JA; Papanikolaou, K; Theodorakopoulou, V; Vrentzos, G, 2021) |
| "Hypertension is the highest risk factor for disease globally." | ( Atherton, I; Suadoni, MT, 2021) |
| "Hypertension is a multifaceted condition influenced by genetic and environmental factors and estimated to cause 9." | ( Collister, JP; Hartson, R; Johnson, TJ; Nahey, DB; Pestana-Oliveira, N; Weber, B, 2021) |
| "Hypertension is a common chronic disease that can lead to serious health problems." | ( An, J; Chen, M; Ma, Y; Ren, J; Yang, H, 2021) |
| "Hypertension is an important public health concern that affects millions globally, leading to a large number of morbidities and fatalities." | ( Aschner, M; Lopes, ACBA; Martins, AC; Paoliello, MMB; Santos, AAD; Skalny, AV; Tinkov, AA, 2021) |
| "Hypertension is characterized by endothelial dysfunction, vascular remodeling, and rearrangement of the extracellular matrix." | ( Bolor-Erdene, E; Mei, Y; Tian, D; Wang, L; Zhang, S; Zhou, L, 2020) |
| "Older age and hypertension are considered as risk factors for CKD among commercial drivers." | ( Akbarpour, S; Mahboobi, M; Mousavi Movahed, SM; Najafi, A; Saraei, M; Taghizadadeh, F, 2021) |
| "Hypertension is often associated with metabolic changes." | ( Consolim-Colombo, FM; Delle, H; Egan, BM; Lopes, HF; Motta E Motta, J; Souza, LN; Vieira, BB, 2021) |
| "Salt-sensitive hypertension is a risk factor for cardiovascular disease." | ( Chen, M; Chen, S; Chen, X; Jin, Y; Ouyang, Y; Tian, Z; Yang, P; Zeng, L; Zhao, X; Zheng, X; Zhou, L, 2021) |
| "Salt-sensitive (SS) hypertension is accompanied with severe cardiorenal complications." | ( Domondon, M; Ilatovskaya, DV; Polina, I; Sarsenova, E; Schibalski, RS; Spicer, MJ; Sultanova, RF, 2021) |
| "Hypertension is a major public health problem, affecting more than a quarter of the world's population causing serious cardiovascular problems." | ( Aguilar Aldrete, ME; Cabrera-Pivaral, CE; Flores-Alvarado, LJ; López-Toledo, S; Parada-Luna, F; Ramírez-García, SA; Ruiz, DM, 2022) |
| "Systemic arterial hypertension is considered the foremost cardiovascular risk factor, and it is important to examine different therapies that help prevent and treat it, especially when associated with other cardiovascular risk factors." | ( Borges, ACR; Costa, HA; da Silva, DP; de Araujo, SA; de Oliveira, MNS; Dias, CJM; Filho, NS; Martins, VA; Mendes, VS; Mostarda, CT; Ribeiro, RM, 2021) |
| "Hypertension is a leading cause of cardiovascular disease in adults; preclinical associations between hypertension and cardiovascular disease are seen in childhood." | ( Brathwaite, KE; Kaskel, FJ; Levy, RV; Melamed, ML; Reidy, K; Sarathy, H, 2021) |
| "Hypertension is a common disease found in 1." | ( Choi, YH; Huh, DA; Moon, KW, 2021) |
| "Hypertension is common in patients with atrial fibrillation (AF) and carries an additional risk for complications, most notably stroke and bleeding." | ( Harskamp, RE; Himmelreich, JCL; Lopes, RD; Lucassen, WAM; Parati, G; Weert, HCPMV, 2022) |
| "Hypertension is the most prevalent chronic disease and a risk factor for various diseases." | ( Ding, YJ; Jia, QJ; Li, YY; Lv, SC; Wang, YJ; Zhang, A; Zhang, JP; Zhang, WQ; Zhang, XN; Zhu, YP, 2021) |
| "Essential hypertension is the most common cardiovascular (CV) risk factor, being primarily involved in the pathogenesis of CV disease and mortality worldwide." | ( Battistoni, A; Citoni, B; Figliuzzi, I; Gallo, G; Presta, V; Tocci, G; Volpe, M, 2021) |
| "Hypertension is a very common cardiovascular disease." | ( Al-Darraji, AH; Jabbar, AS; Neamah, NF, 2021) |
| "Hypertension is a prevalent yet poorly understood feature of polycystic kidney disease." | ( Goodchild, AK; Hildreth, CM; McMullan, S; Phillips, JK; Underwood, CF, 2022) |
| "Hypertension is a serious public health problem worldwide." | ( Huang, YH; Liu, JG; Miao, CY; Qing, SL; Su, DF; Tian, JS; Wang, P; Wang, SN; Xu, JY; Xu, TY, 2021) |
| "Hypertension is a complex and multifactorial disorder caused by lifestyle and environmental factors, inflammation and disease-related genetic factors and is a risk factor for stroke, ischemic heart disease and renal failure." | ( Adler, J; Aïssi, D; Duque Escobar, J; Längst, N; Lukowski, R; Müller, C; Schweigert, O; Tong, T; Trégouët, DA; Zeller, T, 2021) |
| "Hypertension is a common disease of the cardiovascular system which may arise solely or as a comorbidity of other disorders." | ( Bhatt, LK; Hussain, T; Raut, D; Selokar, I, 2021) |
| "Hypertension is associated with chronic inflammation in the tissues and organs that are involved in the regulation of arterial pressure, such as kidneys and blood vessels." | ( Del Hierro Rada, M; Escobar Arregocés, FM; Hernández Meza, FJ; Latorre Uriza, C; Roa, NS; Sáenz Martinez, MJ; Velosa-Porras, J, 2021) |
| "Prehypertension is a state of above-normal blood pressure that does not meet the criteria for the diagnosis of hypertension and its prevalence estimated in population-based samples ranges from 22 to 52%." | ( Itrat, M; Khan, MI; Mobeen, A; Siddiqui, MA, 2021) |
| "Hypertension is one of the main cardiovascular risk factors." | ( Abad Pérez, D; Bellisco Roncal, S; García Polo, I; Ibáñez Sanz, P; Rodríguez Salvanés, FJ; Suárez Fernández, C, 2022) |
| "Hypertension is a common disease for human with high morbidity and mortality, and olmesartan medoxomil (OM) is widely used in the therapy of hypertension." | ( Dushkin, AV; Feng, Z; Ren, W; Su, W; Zhang, Q; Zhao, Y, 2022) |
| "Arterial hypertension is a common and life-threatening condition and poses a large global health burden." | ( Blankestijn, PJ; Fischell, TA; Kandzari, DE; Lobo, MD; Mahfoud, F; Parise, H; Pathak, A; Persu, A; Schmieder, RE; Weber, M, 2021) |
| "Hypertension is a prevalent condition among SARS-CoV-2 infected patients." | ( Amat-Santos, IJ; Antúnez-Muiños, P; Aparisi, Á; Cabezón-Villalba, G; Cacho Antonio, CE; Candela, J; Catalá, P; Dueñas, C; García-Granja, PE; Gil, JF; Gómez, I; González Ferrero, T; González-Juanatey, JR; Jiménez Ramos, V; López-Otero, D; López-Pais, J; Marcos-Mangas, M; Otero-García, O; Pérez-Poza, M; Revilla, A; Rojas, G; San Román, JA; Uribarri, A; Veras, C, 2022) |
| "Hypertension is the most prevalent and potentially modifiable risk factor for AF." | ( Feng, J; Gan, Y; Jiang, H; Ma, H, 2021) |
| "Hypertension is a leading risk factor for cerebrovascular disease and loss of brain health." | ( De Silva, TM; Faraci, FM; Grobe, JL; Modrick, ML, 2021) |
| "Hypertension is associated with excessive reactive oxygen species (ROS) production in vascular cells." | ( Champin, T; Chevrollier, A; Fassot, C; Grenier, C; Grimaud, L; Henni, S; Henrion, D; Lelièvre, E; Lenaers, G; Loufrani, L; Munier, M; Nguyen, PMC; Proux, C; Prunier, D; Reynier, P; Richard, A; Robert, P; Sarzi, E; Vessières, E, 2021) |
| "Hypertension is a chronic condition that requires lifelong therapeutic management." | ( Chua, CYX; Di Trani, N; Grattoni, A; Liu, HC; Liu, X; Qi, R; Viswanath, DI, 2021) |
| "Hypertension is a recognized comorbidity for COVID-19." | ( Gedara, NIM; Jaberi-Douraki, M; Kawakami, J; Meyer, E; Riviere, J; Wyckoff, GJ; Xu, X, 2021) |
| "Hypertension is a leading cause of chronic kidney disease worldwide." | ( Biederman, L; Brodsky, SV; Hebert, L; Hemminger, J; Ivanov, I; Medipally, A; Satoskar, AA; Scarl, R; Ware, K; Xiao, M; Yildiz, V, 2021) |
| "Hypertension is common in hemodialysis (HD) patients." | ( Li, P; Mc Causland, FR; Mothi, SS; Sabbisetti, V; Singh, AT; Waikar, SS, 2021) |
| "Essential hypertension is a pivotal risk factor for the development of cardiovascular disease (CVD)." | ( Ehlert, U; Gideon, A; Sauter, C; von Känel, R; Wirtz, PH, 2021) |
| "Accelerated hypertension is an issue with many targeted therapies for lung cancer." | ( Chen, G; Chen, W; Cheng, Y; Dong, J; Han, B; He, J; Jin, F; Li, B; Li, K; Liu, Z; Luo, Y; Nan, K; Shi, J; Shi, Y; Wang, H; Wang, Q; Wang, X; Wang, Z; Wu, L; Zhang, L, 2021) |
| "H type hypertension is defined as homocysteine (Hcy) ≥ 10 μmol/L in combination with primary hypertension." | ( Cao, H; Cui, ZQ; Ge, JB; Gu, ZH; Hong, B; Hu, JL; Jin, XJ; Lv, XC; Qian, XL; Shen, L; Tang, MN; Tang, WQ; Yao, ZF; Zhang, J; Zhang, L; Zhou, J, 2021) |
| "Hypertension is the major risk factor for SVDs, but how hypertension damages the brain microcirculation is unclear." | ( Dabertrand, F; Ferris, HR; Greenstein, AS; Harraz, OF; Hill-Eubanks, DC; Koide, M; Longden, TA; Nelson, MT; Wellman, GC, 2021) |
| ": Hypertension is a major risk factor for cardiovascular disease, kidney disease, and premature death." | ( Bakker, SJL; Connelly, MA; Dullaart, RPF; Franssen, CFM; Garcia, E; Groothof, D; Kema, IP; Kremer, D; Post, A; Sokooti, S; Swarte, JC; Vogelpohl, FA; Wallimann, T, 2022) |
| "The prevalence of hypertension is increasing globally, while strategies for prevention and treatment of hypertension remain limited." | ( Huang, S; Jia, Z; Niu, Y; Shi, W; Wang, S; Yu, J; Zhang, A; Zhang, Y; Zhou, W, 2021) |
| "Hypertension is thought to cause abnormal platelet activation and increases the risk of thrombosis, but the related mechanism is still vague." | ( Chen, X; Fu, W; Huang, W; Ji, C; Li, S; Li, Y; Ming, Y; Niu, H; Sun, Q; Wei, Z; Xin, G; Yuan, J; Zhao, W; Zhu, Y, 2021) |
| "Hypertension is one of the most common complications of chronic kidney disease (CKD)." | ( Chen, X; Chen, Y; Deng, C; Dong, W; Feng, Z; Hu, J; Ke, G; Kuang, S; Li, R; Li, S; Li, Z; Lian, Z; Liang, H; Liang, X; Liao, R; Lin, T; Liu, S; Ma, J; Shi, W; Yang, Z; Zhang, L, 2021) |
| "Hypertension is the most prevalent disease in both men and women." | ( Amiri-Nikpour, MR; Dindarian, S; Mohammadi, H; Mohammadi, S; Mosarrezaii, A; Rahimzadeh, S, 2021) |
| "Severe hypertension is a risk factor for sustained hypertension after pregnancy." | ( Damodaram, M; Frise, C; Wiles, K, 2021) |
| "Hypertension is a major risk factor for cardiovascular and renal diseases in the United States and worldwide." | ( Ard, JD; Cohen, JB; Egan, BM; Hall, JE; Hall, ME; Lavie, CJ; Ma, J; Ndumele, CE; Schauer, PR; Shimbo, D, 2021) |
| "Hypertension is a global public health problem." | ( Blinova, TV; Fomina, YN; Ivanova, YV; Kolesov, SA; Strakhova, LA; Troshin, VV; Umnyagina, IA, 2021) |
| "Therapy-resistant hypertension is a serious medical problem, causing end-organ damage, stroke, and heart failure if untreated." | ( Balitzki, J; Boden, K; Boehm, M; Boehme, P; Dinh, W; Homann, S; Hüser, J; Mondritzki, T; Sandner, P; Schütt, KA; Truebel, H; Vogel, J, 2021) |
| "Hypertension is one of the primary causes of morbidity and premature mortality among the working-age population in India." | ( Kothavale, A; Puri, P; Yadav, S, 2022) |
| "Hypertension is one of its most common adverse effects, leading to discontinuation of the drug and limited clinical usefulness." | ( Chen, J; Liu, XL; Lv, B, 2022) |
| "Hypertension is the leading preventable risk factor for cardiovascular disease and premature death worldwide." | ( Arai, KJ; Finizola, B; Finizola, RM; Flores, Y; Granero, R; Gutiérrez-Valencia, M; Infante, E; Leache, L; Pardo Pardo, J, 2021) |
| "Hypertension is associated with an unexpectedly high burden of cardiovascular mortality, and contributes to an increasing proportion of IHD deaths and a decreasing proportion of stroke deaths." | ( Gupta, R; Jha, P; Ke, C; Shah, BR; Stukel, TA; Xavier, D, 2021) |
| "Hypertension is a major public health problem that increases the risk of cardiovascular and kidney diseases." | ( Belizán, JM; Cafferata, ML; Ciapponi, A; Cormick, G; Cormick, MS, 2021) |
| "Hypertension is a well-known risk factor for RVO." | ( Bae, EH; Choi, HS; Han, KD; Kim, CS; Kim, SW; Ma, SK; Oh, TR, 2021) |
| "Hypertension is a common pathological condition predisposing to a higher occurrence of cardiovascular diseases and events." | ( Gallo, G; Rubattu, S, 2022) |
| "Hypertension is one of the important causes of cardiovascular diseases, and the imbalance of vascular homeostasis caused by oxidative stress and endothelial inflammation occurs throughout hypertension pathogenesis." | ( Cai, X; Deng, L; Fan, G; Guo, R; Li, L; Liu, W; Ni, J; Xu, Q; Zhang, D; Zhao, Y, 2022) |
| "Hypertension is a risk factor for cognitive decline and dementia." | ( Heizhati, M; Li, N; Liu, Y; Luo, Q; Wang, M; Yao, X; Yuan, Y; Zhu, Q, 2022) |
| "Hypertension is associated with more severe disease and adverse outcomes in COVID-19 patients." | ( Andreini, D; Bertini, M; Campo, G; Carugo, S; Cereda, A; Colombo, A; Elia, M; Esposito, A; Giannini, F; Iacovoni, A; Khokhar, A; Loffi, M; Palmisano, A; Patelli, G; Pontone, G; Rapezzi, C; Sangiorgi, GM; Toselli, M; Tumminello, G; Vignale, D, 2022) |
| "Hypertension is becoming increasingly prevalent among the elderly." | ( Auttama, N; Boonyathee, S; Bootsikeaw, S; Choowanthanapakorn, M; Dokpuang, D; Kantow, S; Ong-Artborirak, P; Panta, P; Seangpraw, K; Tonchoy, P, 2021) |
| "Hypertension is one of the major adverse effects of tyrosine kinase inhibitors (TKIs) targeting vascular endothelial growth factors." | ( Chen, J; Guo, L; Li, C; Ma, L; Shao, X; Wang, Q; Wang, W; Yu, J, 2022) |
| "Hypertension is the major public health concern; leading to cardiovascular disease." | ( Sileshi, B; Urgessa, F; Wordofa, M, 2021) |
| "Hypertension is a major risk factor for the pathogenesis of vascular dementia and Alzheimer's disease." | ( Kuruppu, S; Rajapakse, NW; Tran, S, 2022) |
| "Hypertension is the leading risk factor for cardiovascular disease in India, but less than 10% of the estimated people with hypertension have blood pressure under control." | ( Bhargava, B; Dhaliwal, RS; Durgad, K; Gill, S; Gopal, BK; Kaur, P; Kunwar, A; Mallela, M; Pathni, AK; Saxena, A; Sharma, M; Swasticharan, L; Tayade, S; Tullu, FT, 2021) |
| "Hypertension is a global public health challenge." | ( Kumma, WP; Lindtjørn, B; Loha, E, 2021) |
| "Hypertension is a major risk factor for intimal hyperplasia (IH) and re-stenosis following vascular and endovascular interventions." | ( Allagnat, F; Corpataux, JM; Déglise, S; Deslarzes-Dubuis, C; Lambelet, M; Longchamp, A; Macabrey, D; Ozaki, CK, 2022) |
| "Hypertension is the most important cardiovascular risk factor in India, and representative studies of middle-aged and older Indian adults have been lacking." | ( Bloom, DE; Hu, P; Lee, J; Meijer, E; Sekher, TV; Wilkens, J, 2022) |
| "Hypertension is common in patients with type 2 diabetes who carry increased cardiovascular risk; however, it is unknown how frequently they are tested for PA." | ( Libianto, R; Tan, SJ; Wong, J; Yang, J, 2023) |
| "Hypertension is a chronic disease associated with chronic inflammation involving activated macrophages." | ( Bryniarski, P; Marcinkiewicz, J; Nazimek, K, 2021) |
| "Hypertension is a major public health problem that increases the risk of cardiovascular and kidney diseases." | ( Belizán, JM; Cafferata, ML; Ciapponi, A; Cormick, G; Cormick, MS, 2022) |
| "Uncontrolled hypertension is an important cardiovascular risk factor and therefore requires effective approaches to patient management." | ( Abdullakutty, J; Abhyankar, M; Dalal, J; Das, MK; Fulwani, M; Guha, S; Gupta, R; Kahali, D; Mohan, JC; Mohanan, PP; Nair, T; Narasimhan, C; Ram, CVS; Ray, S; Revankar, S; Roy, DG, 2022) |
| "Hypertension is a common chronic disease, which leads to cardio-cerebrovascular diseases, and its prevalence is increasing." | ( Fan, T; Feng, X; Gao, R; Ge, W; Guo, W; Hou, Y; Song, X; Wang, J, 2022) |
| "Hypertension is one of the most challenging public health problems worldwide." | ( Cao, R; Chen, Y; Ding, R; Dong, G; Dong, Z; Du, J; Fan, J; Gao, Y; Hua, Q; Jiang, W; Lai, X; Li, Z; Mao, J; Wang, X; Wu, S; Wu, W; Wu, Z; Xiong, S; Xu, Y; Yuan, H; Zhang, G; Zhang, J; Zhen, H; Zhou, X, 2022) |
| "Hypertension is associated with higher morbidity and mortality burden, and is reported to pose severe repercussions on those above the age of 60 years." | ( Kothavale, A; Puri, P; Sangani, PG, 2022) |
| "Hypertension is a common condition that is a risk factor for cardiovascular disease, a primary cause of mortality worldwide." | ( Aloud, BM; Bouchard, J; Malunga, LN; Netticadan, T; Raj, P; Thandapilly, SJ; Valookaran, AF, 2022) |
| "Hypertension is a severe public health problem that induces cardiac injury with alterations of gene expressions." | ( Chen, H; Qiao, H; Wei, F; Zhao, Q, 2022) |
| "Hypertension is the leading risk factor for cardiovascular disorders." | ( Chen, Y; Dong, Z; Guo, Y; Jin, H; Li, X; Liu, X; Liu, Y; Song, J; Wang, N; Xu, Y; Zhang, M; Zhang, Z; Zhong, J, 2022) |
| "Hypertension is the leading cause of morbidity and mortality globally among all cardiovascular diseases." | ( Cao, X; Li, X; Lv, J; Zhu, LJ, 2023) |
| "Hypertension is one of the major causes of cardiac damage." | ( Bal, NB; Bostanci, A; Demirel-Yilmaz, E; Dönmez, MO; Sadi, G; Uludag, MO, 2022) |
| "Hypertension is one of the most prevalent cardiovascular disorders worldwide, affecting 1." | ( Chen, X; Gao, H; Li, F; Sun, Q; Wang, J; Wu, H; Xu, J; Yang, R; Yuan, S, 2022) |
| "Hypertension is a high-risk factor for developing coronary heart disease and stroke." | ( Bai, L; Chen, Y; Gao, J; Guo, X; Lai, B; Shang, F; Wang, C; Wen, E, 2022) |
| "Hypertension is highly prevalent and associated with the elevated risks of cardiovascular diseases, dementia, and physical disabilities among adults." | ( Chen, T; Jiang, H; Li, L; Lin, J; Lin, S; Lin, Y; Liu, L; Lu, Z; Shen, H; Su, Y; Tang, C; Wang, Y; Zhang, J; Zhang, Y; Zhao, B; Zhao, Z; Zhou, L, 2022) |
| "Hypertension is a major global health problem." | ( Gadallah, M; Khodir, SA; Shabaan, A; Sweed, E, 2022) |
| "Systemic arterial hypertension is the most common preventable risk factor for all causes of morbidity and mortality worldwide with a prevalence of 35-40% of the adults." | ( Abdelsattar, AT; Cherfaoui, O; Elmoursi, A; Farhat, AM; Habboush, S; Masoud, AT; Sofy, AA, 2022) |
| "Hypertension is considered one of the most persistent public health issues and the single largest contributor to avoidable morbidity and mortality in India." | ( Kannaujiya, AK; Rani, R; Sikarwar, A; Talukdar, P, 2023) |
| "The prevalence of hypertension is increasing among all ethnic groups across the globe with only a handful of studies from India addressing the prevalence of hypertension among tribal population." | ( Ali, SA; Ganie, MA; Nisar, S; Parvez, T; Ramakrishnan, L; Rashid, A; Robbani, I; Sahar, T; Sreenivas, V; Viswanath, SA; Wani, IA, 2021) |
| "Hypertension is a major risk factor of cardiovascular diseases, which is mainly caused due to over activation of renin-angiotensin system." | ( Gautam, S; Gupta, S; Tripathi, J, 2023) |
| "Hypertension is modeled as overactive renal sympathetic nervous activity." | ( Layton, AT; Leete, J; López-Hernández, FJ; Wang, C, 2022) |
| "Hypertension is the leading risk factor for endothelial dysfunction and the progression of dementia that is of vascular origin." | ( Gaur, N; Jayant, S; Kharkwal, H; Sharma, B; Sharma, BM; Sharma, P; Singh, B, 2022) |
| "While hypertension is associated with increased EAA in several tissues, many pathologies are associated with organ-specific age acceleration." | ( Horvath, S; Jamieson, BD; Kobor, MS; Levine, AJ; Lin, DTS; Morgello, S; Said, JW; Singer, E; Yong, WH; Zoller, JA, 2022) |
| "Hypertension is a major risk factor for cardiovascular disease (CVD) as well as a major contributor to all-cause mortality and disability worldwide." | ( Al Attar, AA; Bitto, A; Eid, AH; El-Yazbi, AF; Fahed, GI; Hoballah, MM; Nasser, SA; Orekhov, AN; Pedersen, S, 2022) |
| "Hypertension is a major cause of morbidity and mortality worldwide." | ( Gaciong, Z; Hostalek-Gottwald, U, 2022) |
| "Hypertension is a major risk factor for ischemic heart disease and stroke." | ( Amarchand, R; Krishnan, A; Kulothungan, V; Mathur, P, 2023) |
| "Hypertension is a leading cause of cardiovascular disease and chronic kidney disease, resulting in premature death and disability." | ( Balasubramanian, R; Mohamed Pakkir Maideen, N; Muthusamy, S; Nallasamy, V, 2022) |
| "Hypertension is a common comorbidity among severe COVID-19 patients." | ( A Alattar, R; A Elrayess, M; A Hssain, A; Abdelmajid, A; Abusriwil, H; Al Samawi, M; Al Suwaidi, J; Al-Maslamani, M; Al-Ruweidi, MKAA; Alhariri, B; Almuraikhy, S; Nair, A; Omar Saad, M; Omrani, AS; Parengal, J; T Zedan, H; Yalcin, HC; Yassine, HM, 2022) |
| "Hypertension is a vital risk factor for heart failure, while cardiac rehabilita-tion can effectively improve cardiac function of heart failure patients." | ( Huang, Y; Lan, B; Nong, W; Zhang, D; Zhang, Y, 2022) |
| "Hypertension is a highly prevalent disease with serious cardiovascular and renal complications." | ( Ahmadi, A; Heydarzadeh, R; Kojuri, J; Montaseri, M; Parizi, MM; Rahmani, M; Sharifi, F; Vafa, RG; Zamiri, B, 2022) |
| "Hypertension is a major risk factor for cardiovascular disease and Chinese herb monomers could provide new structural skeletons for anti-hypertension new drug development." | ( Bai, TT; Cao, HL; Chen, YL; He, CX; Li, AH; Li, HJ; Li, L; Li, PQ; Liu, JL; Liu, YX; Qin, W; Su, XL; Wang, JK; Wang, M; Wu, SP; Xing, L; Zhao, D; Zhou, X, 2022) |
| "Hypertension is a prominent representative of CVD." | ( Gu, Y; Xiao, H; Yan, Y; Zhang, Y, 2022) |
| "Hypertension is a leading risk factor for cardiovascular disease and all-cause mortality globally." | ( De Bhailis, ÁM; Kalra, PA, 2022) |
| "Hypertension is common in patients with heart failure (HF), but less is known about resistant hypertension." | ( Benson, L; Dahlström, U; Hage, C; Jackson, AM; Jhund, PS; Lund, LH; McMurray, JJV; Petrie, MC; Savarese, G, 2022) |
| "Hypertension is a risk factor of poor stroke outcomes and associated with antiplatelet resistance." | ( Bath, PM; Chen, G; Huang, P; Jiang, Y; Jing, J; Johnston, SC; Li, H; Li, Z; Lin, J; Liu, L; Meng, X; Tian, X; Wang, A; Wang, F; Wang, Y; Xie, X; Zhao, X; Zuo, Y, 2022) |
| "Hypertension is a major cardiovascular risk factor that is responsible for a heavy burden of morbidity and mortality worldwide." | ( Agabiti Rosei, C; Carollo, C; Cottone, S; De Ciuceis, C; Del Pinto, R; Ferri, C; Muiesan, ML; Mulè, G; Rizzoni, D; Vadalà, M, 2022) |
| "Hypertension is a key risk factor for ischemic heart disease and atherosclerosis." | ( El Mously, DA; El-Sayed, GM; Hassan, NY; Mostafa, NM, 2022) |
| "Arterial hypertension is one of the criteria for this diagnosis and a determinant of damage to major target organs." | ( Lozhkina, NG; Spiridonov, AN, 2022) |
| "Hypertension is a global public health problem." | ( Chakraborty, S; Dalal, K; Lee, MS; Ussatayeva, G, 2022) |
| "Hypertension is a common chronic cardiovascular disease reported among both men and women." | ( Baskaran, R; Chen, RJ; Day, CH; Ho, TJ; Huang, CY; Kuo, WW; Lin, JY; Lin, MY; Lin, YM; Padma, VV, 2022) |
| "Hypertension is one of the main factors of cardiovascular disease worldwide and is strongly related to the overall mortality." | ( Ahmad, H; Chen, M; Gao, D; Ouyang, Y; Tian, Z; Yang, P; Yang, Z; Zeng, L; Zheng, X, 2022) |
| "Hypertension is known as a major factor for global mortality." | ( Deng, H; Li, M; Li, Y; Li, Z; Liu, J; Shen, J; Xie, X, 2022) |
| "Hypertension is one of the major issues worldwide and one of the main factors involved in heart and kidney failure." | ( Ahmad, H; Khan, A; Khan, T; Tian, Z; Umbreen, S; Wei, DQ; Xuewei, Z, 2022) |
| "However, pain and hypertension are important side effects of conventional PDT (c-PDT)." | ( Enk, A; Gholam, P; Hartmann, J; Keller, A, 2022) |
| "Hypertension is a prevalent risk factor for cardiovascular disease." | ( Ihm, SH; Jeong, SH; Kim, BS; Seo, SM; Yi, JE, 2022) |
| "Hypertension is highly prevalent in patients with type II diabetes mellitus." | ( Hr, N; Metri, KG; Mohanty, S; Palukuru, S; Patil, SS; Raghuram, N; S Ram, CV; Singh, A, 2022) |
| "Hypertension is frequently comorbid with the disorders of glucose and lipid metabolism." | ( Chen, Z; Guo, J; Rong, X; Wang, Z; Yang, B; Zhu, Q, 2022) |
| "Hypertension is a common and serious adverse effect of calcineurin inhibitors, including cyclosporine and tacrolimus (FK506)." | ( Chen, SR; Pan, HL; Shao, JY; Zhou, JJ, 2022) |
| "Hypertension is a leading risk factor for cardiovascular disease mortality." | ( Armstrong, ND; Arnett, DK; Chekka, LMS; Claas, SA; Cooper-DeHoff, RM; Gong, Y; Hidalgo, BA; Irvin, MR; Johnson, JA; Jones, AC; Limdi, NA; McDonough, CW; Nahid, NA; Nguyen, NHK; Srinivasasainagendra, V; Tanner, RM; Tiwari, HK, 2022) |
| "Hypertension is a major public health concern and poses a significant risk for sudden cardiac death (SCD)." | ( Cooper, STE; Haines, ZHR; Malone, GO; Meijles, DN; Sheppard, MN; Westaby, JD, 2022) |
| "Hypertension is a public health issue touted as a "silent killer" worldwide." | ( Muhammad, T; Paul, R; Rashmi, R; Srivastava, S, 2022) |
| "Arterial hypertension is a global public health concern." | ( Perusquía, M, 2022) |
| "Hypertension is one of the most common chronic diseases, and dietary factors play an important role in hypertension." | ( Qian, Y; Wang, W; Wang, X; Wang, Y; Wu, J; Yang, B; Zheng, H, 2023) |
| "Hypertension is the leading single preventable risk factor for cardiovascular disease." | ( Bhargava, B; Durgad, K; Gupta, S; Kaur, P; Kunwar, A; Sharma, M, 2023) |
| "Hypertension is a common feature in Cushing's syndrome and may persist after normalizing hormone excess and discontinuing steroid therapy." | ( Beuschlein, F; Biermasz, NR; Castinetti, F; Di Dalmazi, G; Elenkova, A; Fallo, F; Fassnacht, M; Isidori, AM; Kastelan, D; Korbonits, M; Newell-Price, J; Parati, G; Petersenn, S; Pivonello, R; Ragnarsson, O; Reincke, M; Tabarin, A; Theodoropoulou, M; Tsagarakis, S; Valassi, E; Witek, P, 2022) |
| "Hypertension is an important public health challenge, affecting up to 30-50% of adults worldwide." | ( Chang, YH; Chen, WH; Huang, LT; Sheen, JM; Su, CH; Tain, YL; Yu, HR, 2022) |
| "Hypertension is the most important risk factor for the development of terminal cardiovascular diseases, such as heart failure, chronic kidney disease, and atherosclerosis." | ( Costa, TJ; Fontes, M; Hester, S; Linder, BA; McCarthy, CG; Pernomian, L; Robinson, AT; Wenceslau, CF, 2022) |
| "Hypertension is a major cardiovascular risk factor that affects most countries including those of Africa." | ( Auger, C; Chaker, AB; Gbaguidi, FA; Heintz, D; Hounguè, U; Remila, L; Schini-Kerth, VB; Tokoudagba, JM; Villette, C, 2022) |
| "Systemic arterial hypertension is one of the leading causes of morbidity and mortality in the general population, being a risk factor for many cardiovascular diseases." | ( Jose, PA; Simões E Silva, AC; Vaz de Castro, PAS, 2022) |
| "Hypertension is a complex condition and a strong interplay of multiple genetic, epigenetic and environmental factors is involved in its etiology." | ( Ashfaq, UA; Aslam, S; Fatima, I; Ihsan, H; Kalsoom, S; Masoud, MS; Qasim, M; Rehman, A, 2022) |
| "Hypertension is a confirmed risk factor for cerebral hemorrhage in humans." | ( Ai, L; Di, YL; Fei, XC; He, RQ; Huang, N; Li, JJ; Lyu, JH; Tong, ZQ; Yao, DD; Yu, Y; Zhao, SJ, 2022) |
| "Hypertension is one of the risk factors for cerebro-cardiovascular and renal (CCR) diseases." | ( Minatoguchi, S, 2022) |
| "Hypertension is common in CKD patients and many mechanisms inducing it (upregulation of renin-angiotensin-aldosterone system, endothelial dysfunction and atherosclerosis) may be influenced by XOR products." | ( Battelli, MG; Bolognesi, A; Bortolotti, M; Polito, L, 2022) |
| "Hypertension is characterised by activation of the sympathetic nervous system from early to late phases, which makes beta-blockers an appropriate treatment seen from a pathophysiological viewpoint, especially in patients with an elevated heart rate." | ( Esler, M; Grassi, G; Kjeldsen, SE; Kreutz, R; Mancia, G; Pathak, A, 2022) |
| "Hypertension is linked to hyperpolarization-activated cyclic nucleotide-gated (HCN) function, expressed in excitable and non-excitable cells." | ( Cangussú, SD; Chianca-Jr, DA; Chírico, MTT; de Menezes, RCA; Gomes, FAR; Machado-Júnior, PA; Montano, N; Noronha, SISR; Ostolin, TLVP; Reis, AB; Ribeiro, MC; Silva, FC; Silva, SCA; Silva, VJD, 2022) |
| "Hypertension is a severe public health risk factor worldwide." | ( Chang, YC; Chen, RJ; Hong, WZ; Huang, CY; Kuo, CH; Kuo, WW; Lu, SY; Mhone, TG; Tsai, BC, 2022) |
| "Hypertension is a common cardiovascular disease that is related to genetic and environmental factors, but its mechanisms remain unclear." | ( Bai, C; Chen, J; Hui, R; Li, H; Lin, Y; Liu, J; Ping, J; Song, L; Su, M; Sun, Y; Wen, H; Xiao, N; Xu, H; Zhang, M; Zhang, Y, 2022) |
| "Hypertension is a major health problem common in the elderly people." | ( Akbari, A; Gao, J; Wang, T, 2022) |
| "Arterial hypertension is a major risk factor for cardiovascular disease." | ( Chen, CH; Cheng, HM; Chia, YC; Huang, WC; Kario, K; Lin, YH; Siddique, S; Sogunuru, G; Tay, JC; Wu, VC, 2022) |
| "Hypertension is a risk factor for neurodegenerative disorders involving inflammation and inflammatory cytokine-producing brain cells (microglia and astrocytes) in the hippocampus and medial prefrontal cortex (mPFC)." | ( Chen, RX; Contoreggi, NH; Glass, MJ; Johnson, MA; Marongiu, R; Marques-Lopes, J; Mazid, S; Milner, TA; Rubin, BR; Welington, D, 2022) |
| "Arterial hypertension is the most prevalent risk factor for stroke." | ( Nussbaumerová, B, 2022) |
| "Hypertension is a frequently occurring adverse effect caused by regorafenib regardless of previous treatment with vascular endothelial growth factor (VEGF) inhibitors in almost all patients." | ( Komatsu, Y; Saito, Y; Sugawara, M; Takekuma, Y, 2022) |
| "Essential arterial hypertension is not a disease that would significantly adversely affect patients in their daily activities." | ( Slíva, J, 2022) |
| "Hypertension is characterized by sympathetic hyperactivity, which is related to the overexcitation of the presympathetic neurons in the rostral ventrolateral medulla (RVLM)." | ( Duan, W; Gao, Y; Leng, YQ; Li, WY; Tan, X; Wang, WZ; Wang, YK; Ye, P, 2022) |
| "Salt-sensitive hypertension is a major risk factor for cardiovascular morbidity and mortality." | ( Ertuglu, LA; Kirabo, A, 2022) |
| "Hypertension is a major public health challenge in low- and middle-income countries (LMICs) and calls for large-scale effective hypertension control programs." | ( Cazabon, D; Hering, D; Krishna, A; Moran, AE; Pathni, AK; Sahoo, SK; Sharma, B, 2023) |
| "Arterial hypertension is among factors with the potential for increasing the risk of cognitive impairment in elderly subjects." | ( Hojnacki, D; Podolsky, R; Schaller, B; Sternberg, Z; Tian, M; Yu, J, 2022) |
| "Hypertension is a recognized risk factor for dementia." | ( Adesuyan, M; Alsugeir, D; Brauer, R; Cheung, ECL; Chui, CSL; Howard, R; Jani, YH; Wong, ICK, 2022) |
| "Hypertension is the most common chronic non-infectious disease and a severe problem for public health in China." | ( Chen, M; Di, B; Hou, C; Hu, C; Liu, M; Su, M; Wang, Y; Xu, P; Yan, F; Zhang, L; Zhong, Y, 2023) |
| "Hypertension is a leading preventable risk factor for cardiovascular disease in hemodialysis patients." | ( Gan, L; Li, W; Li, Z; Liang, Y; Ma, Y; Ren, J; Shen, Y; Wang, M; Xu, M; Zhang, D; Zhao, X; Zuo, L, 2022) |
| "Hypertension is classified into two types which are primary or essential hypertension and secondary hypertension." | ( Elmoursi, A; Kamel, IS; Kassem, A; Khalil, F; Mancy, IME; Mohamed, SED; Mostafa, S; Ramadan, IG; Shabana, H; Zedan, HA, 2022) |
| "Hypertension is the leading cause of cardiovascular affection and premature death worldwide." | ( Carmona-Calero, EM; Castañeyra-Perdomo, A; Castañeyra-Ruiz, L; González-Gómez, M; González-Marrero, I; Hernández-Abad, LG; Soto-Viera, M, 2022) |
| "Obesity and hypertension are closely interrelated as abdominal obesity interferes with the endocrine and immune systems and carries a greater risk for insulin resistance, diabetes, hypertension, and cardiovascular disease." | ( Allam, S; Chedid, R; El Meouchy, P; Karam, S; Karam, W; Wahoud, M, 2022) |
| "Salt-induced hypertension is one of the major issues worldwide and one of the main factors involved in heart and kidney failure." | ( Ahmad, H; Ahmad, N; Chen, M; Du, J; Jin, Y; Khan, A; Li, X; Ouyang, Y; Tian, Z; Yang, P; Yang, Z; Zeng, L; Zhao, X; Zheng, X, 2022) |
| "with hypertension) is associated with additional features including increased fibrosis and can lead to heart failure." | ( Alharbi, HO; Clerk, A; Cooper, STE; Cull, JJ; Fuller, SJ; Glennon, PE; Hardyman, MA; Markou, T; Sugden, PH, 2022) |
| "Hypertension is one of the leading causes of chronic kidney disease characterized with renal fibrosis." | ( Chen, YH; Li, XT; Liang, LR; Liu, XY; Liu, Y; Miao, R; Song, JW; Zhang, MW; Zhang, ZZ; Zhong, JC, 2022) |
| "Hypertension is associated with endothelial dysfunction and decreased nitric oxide (NO)." | ( Crowe-White, KM; DiNatale, JC, 2022) |
| "Hypertension is associated with increased risk of cardiovascular disease (CVD) events (coronary heart disease, heart failure, and stroke) and death." | ( Carey, RM; Moran, AE; Whelton, PK, 2022) |
| "Resistant hypertension is associated with increased cardiovascular risk." | ( Bakris, GL; Bellet, M; Danaietash, P; Dreier, RF; Flack, JM; Haskell, LP; Narkiewicz, K; Sassi-Sayadi, M; Schlaich, MP; Wang, JG; Weber, MA, 2022) |
| "VEGFI-induced hypertension is sodium-sensitive in animal studies." | ( Bins, S; Bovée, DM; de Hoop, EO; de Mik, AVE; Eskens, FALM; Garrelds, IM; Hoorn, EJ; Jan Danser, AH; Koolen, SLW; Mathijssen, RHJ; Mirabito Colafella, KM; van Doorn, L; van Dorst, DCH; Versmissen, J; Visser, WJ, 2023) |
| "Hypertension is a common risk factor for cardiovascular disease and mortality worldwide." | ( Aloud, BM; Bouchard, J; Netticadan, T; Thandapilly, SJ; Valookaran, AF, 2022) |
| "Hypertension is inheritable, and some candidate genes such as leptin and adiponectin have drawn special concerns." | ( Li, Y; Xing, X; Yang, J; Zhang, B; Zhang, Q; Zhang, Z; Zheng, H, 2023) |
| "Hypertension is inheritable, and some candidate genes such as leptin and adiponectin have drawn special concerns." | ( Li, Y; Xing, X; Yang, J; Zhang, B; Zhang, Q; Zhang, Z; Zheng, H, 2023) |
| "Hypertension is a significant public health problem that affects people all over the world." | ( Aldin, SZJ; Baker, LAA, 2022) |
| "Hypertension is a significant public health problem that affects people all over the world." | ( Aldin, SZJ; Baker, LAA, 2022) |
| "Hypertension is the definitive risk factor for cardiovascular disease." | ( Itoh, H; Kurihara, I; Shibata, H; Sone, M; Yokota, K, 2023) |
| "Hypertension is the definitive risk factor for cardiovascular disease." | ( Itoh, H; Kurihara, I; Shibata, H; Sone, M; Yokota, K, 2023) |
| "Hypertension is a well-established risk factor for cardiovascular (CV) events in patients with chronic kidney disease (CKD), heart failure, obesity, and diabetes." | ( Advani, A; Cherney, DZI; Dubrofsky, L; Kugathasan, L, 2023) |
| "Hypertension is a well-established risk factor for cardiovascular (CV) events in patients with chronic kidney disease (CKD), heart failure, obesity, and diabetes." | ( Advani, A; Cherney, DZI; Dubrofsky, L; Kugathasan, L, 2023) |
| "Hypertension is a significant risk factor of cardiovascular diseases (CVDs) with high prevalence worldwide, the current treatment has multiple adverse effects and requires continuous administration." | ( Chen, TT; Chen, WJ; Huang, H; Jin, R; Tang, YH; Wang, XL; Wei, J; Xu, X; Zou, CW, 2023) |
| "Hypertension is a significant risk factor of cardiovascular diseases (CVDs) with high prevalence worldwide, the current treatment has multiple adverse effects and requires continuous administration." | ( Chen, TT; Chen, WJ; Huang, H; Jin, R; Tang, YH; Wang, XL; Wei, J; Xu, X; Zou, CW, 2023) |
| "Hypertension is a complex disorder ensuing necessarily from alterations in the pressure-natriuresis relationship, the main determinant of long-term control of blood pressure." | ( Baranda-Alonso, EM; Díaz-Morales, N; López-Hernández, FJ; Martínez-Salgado, C, 2023) |
| "Hypertension is the most important modifiable risk factor for cardiovascular disease and a leading public health concern." | ( Bonalume Tacito, LH; Cestario, EDES; Cosenso-Martin, LN; da Silva Lopes, V; Fernandes, LAB; Moreno Junior, H; Rubio, TA; Uyemura, JRR; Vilela-Martin, JF; Yugar-Toledo, JC, 2022) |
| "Hypertension is the most common and modifiable risk factor for preventing adverse cardiovascular outcomes in patients with CKD." | ( Liang, L; Shimosawa, T, 2022) |
| "Hypertension is highly prevalent in postmenopausal women." | ( Dillon, KN; Figueroa, A; Fischer, SM; Kang, Y; Maharaj, A; Martinez, MA, 2022) |
| "Hypertension is a multifactorial disease that partially caused by genetic factors, including variation in genes related to lipid metabolism." | ( Jiang, X; Luo, N; Wang, H; Xia, Y; Yang, H; Zhou, T, 2022) |
| "Hypertension is a leading risk of coronary artery disease (CAD)." | ( Li, X; Pan, W; Ren, Y; Wang, M; Yang, F; Yin, D, 2023) |
| "Offspring hypertension is associated with increases in the plasma TMAO concentration and oxidative stress and shifts in gut microbiota." | ( Chang-Chien, GP; Hou, CY; Hsu, CN; Lin, S; Tain, YL, 2023) |
| "Hypertension is the leading risk factor for global disease burden." | ( An, W; Li, D; Qin, L; Zhang, H; Zhang, Y, 2023) |
| "The prevalence of hypertension is higher among Black adults than among White and Hispanic adults." | ( Bhatnagar, A; DeJarnett, N; Hall, ME; Keith, RJ; Konkle, SL; McGraw, KE; Oshunbade, A; Rai, SN; Riggs, DW; Shimbo, D; Xie, Z, 2023) |
| "Hypertension is a major risk factor for cardiovascular diseases, such as strokes and myocardial infarctions." | ( Arbatsky, M; Basalova, N; Chechekhin, V; Efimenko, A; Grigorieva, O; Ivanova, A; Kalinina, N; Karagyaur, M; Kulebyakin, K; Naida, D; Skryabina, M; Sysoeva, V; Tkachuk, V; Tyurin-Kuzmin, P, 2023) |
| "Midlife hypertension is an important risk factor for cognitive impairment and dementia, including Alzheimer's disease." | ( Bakker, ENTP; Coolen, BF; de Vos, J; Heijst, JA; Jongenelen, CAM; Naessens, DMP; Richard, E; Scholl, ER; Strijkers, GJ; Teunissen, CE; van der Wel, NN; VanBavel, E; Wilhelmus, MMM, 2023) |
| "Hypertension is a modifiable cardiovascular risk factor and cause of death worldwide." | ( Hui, J; Lin, Q; Liu, L; Qin, Y; Wang, B; Xu, F; Xue, B; Zhan, Q; Zhao, J, 2023) |
| "Hypertension is the most common cardiovascular disease, and its main harmful effect is chronic damage to target organs." | ( Ai, S; Ao, W; Chen, C; Kong, L; Li, J; Xiao, J; Xu, Y; Yang, Y; Zhang, Y, 2023) |
| "Early detection of hypertension is associated with improved blood pressure control and a reduced risk of cardiovascular diseases." | ( Atnafu, A; Ayele, TA; Balcha, SA; Gelaye, KA; Teshome, DF, 2023) |
| "Uncontrolled hypertension is a major risk factor for cardiovascular diseases (CVDs)." | ( Anandraj, J; Essakky, S; Kar, SS; Kumar, SM; Loganathan, V; Nain, J; Sivanatham, P; Talukdar, R, 2023) |
| "Hypertension is one of the most common disorders encountered, yet pharmacotherapy for resistant hypertension has limited effective options." | ( Dharmarajan, L; Grewal, D; Hussain, A; Khamosh, M; Mahfooz, K; Najeed, S; Ong, K; Tun, HN; Vasavada, A, 2023) |
| "Hypertension is a leading modifiable risk factor for cerebral small vessel disease." | ( Chambers, LC; Dorrance, AM; Jackson, WF; Yen, M, 2023) |
| "Hypertension is a key component of metabolic syndrome and is associated with an increase in morbidity and mortality due to stroke, cardiovascular ailments, and kidney disease." | ( Barone, S; Luo, H; Soleimani, M; Zahedi, K, 2023) |
| "Hypertension is the most common cause of left ventricular hypertrophy, contributing to heart failure progression." | ( Calleros, L; De Giusti, V; Ferrer, EG; Griera, M; Islas, MS; Jaquenod de Giusti, C; Martinez, VR; Martins Lima, A; Portiansky, EL; Rodriguez Puyol, M; Stergiopulos, N; Velez Rueda, JO; Williams, PAM, 2023) |
| "The pathogenesis of hypertension is not fully understood; endothelin 1 (EDN1) is involved in developing essential hypertension." | ( Chen, JY; Lu, MH; Wang, WJ; Yang, TC, 2023) |
| "In fact, hypertension is commonly associated with increased morbidity and mortality." | ( Chen, M; Du, X; Jiang, C; Jiang, Z; Li, X; Liu, J; Ma, Y; Mei, S; Qiao, X; Sun, N; Tang, K; Wang, X; Zhao, Y, 2023) |
| "Posttransplant hypertension is a complex problem requiring individualized management." | ( Kalil, RS; Singh, AP; Weir, MR, 2023) |
| "Hypertension is common in older individuals and is a major risk factor for cardiovascular disease." | ( Kresovich, JK; Sandler, DP; Taylor, JA, 2023) |
| "Hypertension is a most common health problem worldwide and its incidence seems to be increasing on global scale." | ( Israt, S; Nessa, A; Saki, SA, 2023) |
| "Essential hypertension is caused by the interaction of genetic, behavioral, and environmental factors." | ( Armando, I; Jose, PA; Yang, J; Zeng, C, 2023) |
| "Hypertension is a common toxicity in patients with CLL who receive ibrutinib but is manageable in most patients." | ( Burger, JA; Durand, JB; Ferrajoli, A; George, B; Gordon, MJ; Jain, N; Jones, JE; Keating, M; Peterson, C; Wierda, WG, 2023) |
| "Hypertension is one of the most prevalent chronic non-communicable diseases and affects more than 60% of individuals over 60 years of age." | ( Gadanec, LK; Homolka, P; Kovacovicova, P; Kruzliak, P; Kunzova, S; Novak, J; Prosecky, R; Skladana, M; Sochor, O; Soukup, L, 2023) |
| "Hypertension is the leading risk factor for premature death worldwide." | ( Hagström, E; Held, C; Lind, L; Lytsy, P; Marttala, K; Neal, B; Nowrouzi, S; Östlund, O; Sundström, J, 2023) |
| "Hypertension is the largest risk factor affecting global mortality." | ( Chakraborty, S; Cheng, X; Golonka, RM; Jia, W; Joe, B; Lulla, A; Mandal, J; Mei, X; Mell, B; Meyer, K; Piyarathna, DWB; Putluri, N; Putluri, V; Saha, P; Sreekumar, A; Vijay-Kumar, M; Yang, T; Yeo, JY; Yeoh, BS, 2023) |
| "Most patients with hypertension are complicated with insulin resistance (IR), which is one of the risk factors of hypertension and can increase the level of serum homocysteine (Hcy) by affecting Hcy's metabolic enzyme and insulin level." | ( Huang, W; Wen, C; Xu, R; Yu, X, 2023) |
| "Hypertension is one of the leading causes of human death and disability." | ( Hu, S; Lai, M; Liu, Y; Pu, G; Tao, P; Wang, Y; Wang, Z; Xu, C; Yang, C; Zhang, L, 2023) |
| "Chronic hypertension is a major risk factor for cerebral small vessel disease (cSVD)." | ( Blackwill, H; Chang, P; Chow, D; Lee, SJ; Qian, T; Shafie, M; Soun, JE; Stradling, D; Vanderschelden, B; Yu, W; Zhu, Z, 2023) |
| "Obesity and hypertension are major risk factors for cardiovascular diseases that affect millions of people worldwide." | ( Fang, H; Jiang, Z; Khederzadeh, S; Leng, J; Li, J; Liu, W; Liu, X; Lu, X; Wu, O; Xia, J; Yang, F; Yuan, C; Zhang, H; Zhang, X, 2023) |
| "Hypertension is a major healthcare issue that afflicts one in every three adults worldwide and contributes to cardiovascular diseases, morbidity and mortality." | ( Imig, JD, 2023) |
| "Hypertension is among the most prevalent medical conditions globally and a major contributor to chronic kidney disease, cardiovascular disease, and death." | ( Earle, W; Hiremath, S; Juraschek, SP; Morales-Alvarez, MC; Nissaisorakarn, V; Ormseth, G, 2023) |
| "Hypertension is the leading global cause of cardiovascular disease and premature mortality in women." | ( Ahmed, SB; Kalenga, CZ; MacRae, JM; Metcalfe, A; Nerenberg, KA; Robert, M, 2023) |
| "Management of hypertension is important for effective treatment with less burden; therefore, further evaluation is needed." | ( Komatsu, Y; Saito, Y; Sugawara, M; Takekuma, Y, 2023) |
| "Hypertension is a major contributor to global CVD burden." | ( Longkumer, I; Rajkumari, S; Saraswathy, KN; Yadav, S, 2023) |
| "Hypertension is very common and remains often poorly controlled in patients with chronic kidney disease (CKD)." | ( Agarwal, R; Georgianos, PI, 2023) |
| "Hypertension is a major risk factor for heart attack, produce atherosclerosis (hardening of the arteries), congestive heart failure, stroke, kidney infection, blindness, end-stage renal infection, and cardiovascular diseases." | ( Ahmad, H; Ahmad, S; Haque, S; Khan, A; Khan, H; Srivastava, N, 2023) |
| "Hypertension is the most prevalent chronic disease World-wide, and the leading preventable risk factor for cardiovascular disease (CVD)." | ( Baldi, S; Chen, P; Liu, H; Liu, S; Lu, F; Mohammed, SAD; Wang, Y, 2023) |
| "Arterial hypertension is associated with increased morbidity and mortality and research in the field is highly dynamic." | ( Böhm, M; Götzinger, F; Kunz, M; Lauder, L; Mahfoud, F, 2023) |
| "Hypertension is mainly regulated by the renin-angiotensin-aldosterone system (RAAS), with its main mediator being angiotensin II (ANG II)." | ( Adjaye, J; Erichsen, L; Thimm, C; Wruck, W, 2023) |
| "Hypertension is one of the most significant risk factors for many cardiovascular diseases." | ( Makovka, YV; Markel, AL; Oshchepkov, DY; Ponomarenko, MP; Redina, OE, 2023) |
| "Hypertension is the main risk factor of cardiovascular and cerebrovascular diseases." | ( Chen, Y; He, M; Hu, Y; Qin, B; Tan, X; Tang, Y; Wang, N; Wang, R; Yang, K; Yu, L; Zhang, B; Zhang, Y, 2023) |
| "Hypertension is a world-leading cause of cardiovascular disease and premature deaths." | ( Friederich-Persson, M; Marchetti, M; Persson, P, 2023) |
| "Hypertension is the leading cause of death worldwide, affecting 1." | ( Palmer, BF; Sever, P; Vogel Anderson, K; Wang, JG, 2023) |
| "Hypertension is a key risk factor for cardiovascular disease and the leading cause of mortality among Indian adults." | ( Dixit, P; Singh, A, 2023) |
| "Hypertension is a serious global public health issue." | ( Chen, J; Cong, Y; Cui, Y; Guo, J; Jin, T; Wang, H; Yu, R; Zhao, R; Zhou, Z, 2023) |
| "Arterial hypertension is the main preventable cause of premature mortality worldwide." | ( Alcocer, LA; Bryce, A; Cortes, JM; De Padua Brasil, D; Lara, J; Quesada, D; Rodriguez, P, 2023) |
| "Resistant hypertension is associated with increased mortality and morbidity." | ( Avcı, Y; Bıyık, İ; Çizgici, AY; Demir, AR; Özal, E; Püşüroğlu, H, 2023) |
| "Hypertension is associated with adverse maternal and perinatal outcomes, and as treatment improves maternal outcomes, antihypertensive treatment is recommended." | ( Ashworth, D; Battersby, C; Bick, D; Chappell, LC; Green, M; Hardy, P; Leighton, L; Magee, LA; Maher, A; McManus, RJ; Moakes, C; Morris, RK; Myers, J; Nelson-Piercy, C; Rivero-Arias, O; Sparkes, J; Webb, A; Wilson, H, 2023) |
| "Hypertension is characterized by endothelial dysfunction and arterial stiffness, which contribute to the pathogenesis of atherosclerotic cardiovascular diseases." | ( Chen, X; Dong, B; He, J; Huang, H; Liu, S; Liu, Z; Qiu, Y; Su, C; Tao, J; Tu, Q; Wu, X; Xia, W; Xu, S; Zhang, J; Zhang, X; Zhou, Z, 2023) |
| "Hypertension is a major risk factor for cardiovascular diseases." | ( Ampofo, AG; Boateng, EB, 2023) |
| "Hypertension is a major risk factor for cardiovascular disease (CVD) and is associated with increased bone loss due to excessive activity of the local renin-angiotensin system (RAS)." | ( Fan, Z; Kanou, K; Kitaura, H; Lin, A; Ma, J; Marahleh, A; Miura, M; Mizoguchi, I; Narita, K; Noguchi, T; Ohori, F; Ren, J, 2023) |
| "Hypertension is a major risk factor for cardiovascular disease (CVD) and is associated with increased bone loss due to excessive activity of the local renin-angiotensin system (RAS)." | ( Fan, Z; Kanou, K; Kitaura, H; Lin, A; Ma, J; Marahleh, A; Miura, M; Mizoguchi, I; Narita, K; Noguchi, T; Ohori, F; Ren, J, 2023) |
| "Essential arterial hypertension is a risk factor for stroke, myocardial infarction, heart failure, and arterial aneurysm, which are related to the activation of platelets." | ( Aneli, NM; Cardoso, AM; Corralo, VDS; De Sá, CA; Lammers, M; Maciel, SFVO; Mânica, A; Sévigny, J; Zanini, D, 2023) |
| "Newly presenting hypertension is much the same-hold off on first-order antihypertensive(s) and prescribe spironolactone 25 mg/day for 4 weeks." | ( Funder, JW, 2023) |
| "Postpartum hypertension is a common medical complication of pregnancy and is associated with increased healthcare use, including unplanned interactions with the medical system and readmission, which can add significant stress to both a newly postpartum patient and the medical care delivery system." | ( Celi, AC; McElrath, TF; Robinson, JN; Seely, EW; Yoselevsky, EM, 2023) |
| "Hypertension is highly prevalent in patients with polymyositis and dermatomyositis (PM/DM)." | ( Liu, M; Lu, K; Luo, Q; Wang, H; Zhao, T; Zhao, Z, 2023) |
| "Hypertension is the leading preventable risk factor for cardiovascular disease and all-cause mortality worldwide." | ( Behers, BJ; Behers, BM; Davis, JL; Gerhold, CJ; Melchor, J; Mendez Araque, SJ; Meng, Z; Mouratidis, RW; Patel, BS; Paterson, HI; Shah, RS; Swanson, PJ; Sweeney, MJ; Thompson, AJ, 2023) |
| "Hypertension care cascade in resource-limited settings is compromised with a majority of patients with hypertension remaining undiagnosed, untreated, non-adherent, and poorly controlled at every stage." | ( Basu, S; Garg, S; Lalwani, H; Maheshwari, V; Rao, S; Sharma, N; Singh, MM, 2023) |
| "Hypertension care cascade in urban slum-resettlement colony setting revealed a high burden of undiagnosed hypertension, low rates of medication adherence, and poor blood pressure control." | ( Basu, S; Garg, S; Lalwani, H; Maheshwari, V; Rao, S; Sharma, N; Singh, MM, 2023) |
| "Hypertension is the most common and chronic severe health problem globally." | ( Ho, TY; Hsiang, CY; Liao, PY; Lo, HY; Lu, GL, 2024) |
| "Hypertension is a risk factor for HF in patients with breast cancer undergoing DOX chemotherapy." | ( Hwang, HJ; Lee, TG, 2023) |
| "Hypertension is a common disease that affects human health and can lead to damage to the heart, kidneys, and other important organs." | ( Liu, J; Lyu, C; Sun, Z; Wang, W; Wei, Y; Yin, D; Yu, J; Zou, S, 2023) |
| "Hypertension is a serious complication linked to a higher risk for organs." | ( Abbas-Hashemi, SA; Asbaghi, O; Hosseininasab, D; Rastgoo, S; Shiraseb, F, 2023) |
| Excerpt | Reference |
|---|
| "Only recently approved for use in the treatment of hypertension in the US, the beta-adrenergic receptor blocking compound propranolol has been used elsewhere for this purpose since 1964." | ( Frohlich, ED, 1977) |
| "1 The stepped care approach for the treatment of hypertension was adopted in a study at Ain Shams Hospital using hydrochlorothiazide (HCT) and a new beta-blocker, nadolol." | ( El-Mehairy, MM; Hamza, S; Ramadan, M; Shaker, A; Tadros, SS, 1979) |
| "2 Following 12 weeks' treatment of hypertension with the object of reducing the supine BP to 150/90 mmHg or below, there was a reduction of wall thickness so that only two of the eight continued to show ASH." | ( Hill, LS; Monaghan, M; Richardson, PJ, 1979) |
| "The art of treatment of hypertension therefore appears to be in a healthy state and we should expect more advances in the future." | ( Freis, ED, 1979) |
| "Methyldopa is safe to use for the treatment of hypertension in pregnancy in the context of close medical and obstetric supervision." | ( Redman, CW, 1976) |
| "After six years of little or no treatment, the hypertension and mild hyperaldosteronism were promptly decreased by a small dose of dexamethasone." | ( Levine, LS; New, MI; Peterson, RE; Saenger, P, 1976) |
| "Adequate treatment of hypertension requires that the physician understand the pharmacologic actions of antihypertensive agents." | ( Goldberg, LI, 1975) |
| "The use of prostaglandins in the treatment of hypertension is being explored." | ( Slotkoff, LM, 1978) |
| "A special protocol was used to treat arterial hypertension in 21 subjects." | ( Bret, M; Fillastre, JP; Godin, M, 1978) |
| "105 patients with previously untreated hypertension entered the trial and 72 completed it." | ( Nissinen, A; Tuomilehto, J, 1979) |
| "Of these patients 16 had untreated hypertension and 28 had diabetic complications, which ranged from microaneurysms to renal failure and blindness." | ( Burden, AC; Thurston, H, 1979) |
| "Ticrynafen is useful in the treatment of hypertension and in selected cases of chronic congestive heart failure." | ( Kosman, ME, 1979) |
| "A patient treated for hypertension with labetalol developed left ventricular failure." | ( Bayley, TJ; Frais, MA, 1979) |
| "1 The efficacy of labetalol in the treatment of severe hypertension (diastolic greater than or equal to 115 mm Hg) was studied retrospectively." | ( Murphy, MJ; Parsons, V; Williams, LC, 1979) |
| "The effect of long-term treatment of hypertension with propranolol, alone or in combination with hydrochlorothiazide and/or dihydralazine, was investigated in 93 patients with various types of hypertension." | ( Ambrosio, G; Corgnati, A; Dal Palù, C; Palatini, P; Pessina, AC, 1978) |
| "1 Twelve men with untreated essential hypertension in WHO stage I were studied on an outpatient basis to evaluate the haemodynamic long-term effect of a new beta-adrenoceptor blocker, metoprolol." | ( Lund-Johansen, P; Ohm, OJ, 1977) |
| "The major reason for treating hypertension is to avoid complications of the disease as it affects "target organs." | ( Grissom, RL; Gust, WF, 1977) |
| "1 Thirteen men with untreated essential hypertension in WHO stage I were studied on an outpatient basis to evaluate the haemodynamic long-tern effect of a new beta-adrenoceptor blocker, atenolol." | ( Lund-Johansen, P, 1976) |
| "However, a group of subjects with untreated hypertension showed a significantly smaller initial inflow during the suction." | ( Fentem, PH; Yates, JM, 1975) |
| "Three different regimens of drug treatment for hypertension were compared with regard to the development of undesirable side-effects in a group of 53 patients attending a hypertension clinic." | ( Pillay, VK, 1976) |
| "The results confirm that effective treatment of hypertension significantly reduced basal [Ca2+]i in platelets but raise doubts whether elevated basal [Ca2+]i is necessarily the sole mechanism by which the sensitivity of platelets to aggregatory agents is increased in hypertension." | ( Baig, MW; Davies, JA; Lees, AD; Orchard, MA; Perrins, EJ; Prentice, CR; Wilson, J, 1992) |
| "Twelve patients with untreated essential hypertension." | ( Connell, JM; Davidson, G; Jardine, AG; O'Connell, JE, 1992) |
| "The drug has a place in the chronic treatment of hypertension and in the therapy of hypertensive emergencies." | ( Rahn, KH, 1992) |
| "Twenty-one patients with previously untreated essential hypertension were treated with a low dose combination of 50 mg of atenolol and 10 mg of enalapril once daily for 39 months." | ( Behr, U; Franz, IW; Ketelhut, R; Messerli, FH; Toennesmann, U, 1992) |
| "The effect of treatment of hypertension with nifedipine on plasma renin activity, blood serum level of aldosterone in the course of renin test, and cortisol and growth hormone concentrations after stimulation with insulin hypoglycemia was followed during two weeks of treatment in 40 patients with essential hypertension." | ( Kokot, F; Wnuk, R, 1991) |
| "Second, in the treatment of hypertension in pregnancy or preeclampsia, where, according literature, nifedipine would be a valuable therapeutic gun." | ( Palma-Aguirre, JA; Rodríguez-Palomares, C, 1992) |
| "Moreover, treatment of hypertension is critical to reduce morbidity and mortality of cardiovascular disease in these patients, who have an increased risk for such events." | ( Donker, AJ; ter Wee, PM, 1992) |
| "The value of pharmacologically treating mild hypertension and mild hypercholesterolemia is questioned, and the need for well-designed, randomized clinical trials with definitive endpoints to determine a drug's cardioprotective capability is emphasized." | ( Wikstrand, J, 1992) |
| "Diuretics have long been used in the treatment of hypertension and are outstandingly efficacious when used either alone or in combination with other antihypertensive compounds." | ( Papademetriou, V, 1992) |
| "The recently published MRC-trial on treatment of hypertension in older adults showed generally beneficial effects." | ( Osnes, JB, 1992) |
| "We conclude that captopril is useful in treating arterial hypertension associated to lupous nephropathy, but frequent leukocyte counting controls must be done during the first months." | ( de Paco, M; del Baño, MD; Molina Boix, M; Ortega, G; Ruiz, F; Vidal, JB, 1992) |
| "Hypercholesterolaemia and untreated hypertension were more prevalent in Dubbo (threefold and 1." | ( Friedlander, Y; McCallum, J; Simons, J; Simons, LA, 1992) |
| "Theoretically, the method used to treat hypertension can influence spinal cord perfusion pressure and neurologic outcome." | ( Clark, FJ; McCutcheon, K; Mutch, WA; Rosenbloom, M; Sutton, IR; Teskey, JM; Thiessen, DB; Thomson, IR, 1992) |
| "on pharmacologic treatment for hypertension, in the univariate analysis." | ( Kuller, LH; Markovitz, JH; Matthews, KA; Meilahn, EN; Wing, RR, 1991) |
| "Seven Indian patients with untreated cryptogenic hypertension had fewer sodium/potassium pumps than normotensive Indians without family history." | ( Goh, CR; Oh, VM; Taylor, EA, 1991) |
| "These results show that a first-step treatment of hypertension with converting enzyme inhibitors permits better left ventricular function and improves exercise tolerance by way of renin-angiotensin-aldosterone system inhibition." | ( Chen, CY; Chiang, HT; Lin, M, 1991) |
| "Diagnosis and treatment of hypertension need to be improved, especially in men and the Creole ethnic group." | ( Alberti, KG; Chitson, P; Dowse, G; Fareed, D; Gareeboo, H; Korhonen, HJ; Nan, L; Tuomilehto, J; Zimmet, P, 1991) |
| "Therefore the treatment of hypertension demands a multifactorial approach, one that takes into consideration all the risk factors for CHD." | ( Poulter, N, 1991) |
| "In the short-term treatment of mild hypertension where diastolic blood pressure is the sole consideration, drugs outperform diet, and weight loss is beneficial, especially with diuretics." | ( Blaufox, D; Davis, BR; Hawkins, M; Langford, HG; Oberman, A; Wassertheil-Smoller, S; Zimbaldi, N, 1991) |
| "Because beta-blockers are used to treat hypertension, angina, and myocardial infarction, it is important to determine the impact of beta-blockers on fibrinolysis." | ( Hjemdahl, P; Larsson, PT; Olsson, G; Teger-Nilsson, AC, 1991) |
| "Use of SP as a putative agent to treat essential hypertension in humans needs further studies." | ( Colditz, M; Faulhaber, HD; Gurk, C; Martin, G; Stechmesser, G; Urmantcheeva, TG; Wolter, F, 1990) |
| "Carvedilol is a novel treatment for hypertension, having a balanced pharmacology of vasodilation and beta-receptor blockade." | ( Ball, SG; Dixon, S; Hall, S; Hallman, RJ; Harvey, RE; Prescott, RI, 1991) |
| "In conclusion, short-term treatment of hypertension with ramipril has no influence on glucose metabolism in nondiabetic patients." | ( Brunnbauer, M; Kueenburg, E; Ludvik, B; Prager, R; Schernthaner, G, 1991) |
| "Modified stepped-care treatment for hypertension, prescribed without reference to the renin profile, was similar in the three renin groups." | ( Alderman, MH; Cohen, H; Laragh, JH; Madhavan, S; Ooi, WL; Sealey, JE, 1991) |
| "Ketanserin is effective in treating hypertension following coronary artery bypass grafting with an advantage of lack of reflex tachycardia." | ( Boey, WK; Kumar, A; Lee, CN; Lee, EJ; Lee, TL; Woo, M, 1991) |
| "Seven days after the STZ treatment, hypertension was initiated by subcutaneous implantation of deoxycorticosterone acetate and administration of 1% saline in the drinking water (DOCA-NaCl)." | ( Jirakulsomchok, S; Mozaffari, MS; Wyss, JM, 1991) |
| "The pharmacological treatment of hypertension raises not only the dilemma of the election of the most suitable drugs given to each patient, but also that of an effective control of the antihypertensive effect as well as undesirable reactions, including an accentuated hypotension." | ( Arenoso, HJ; Godoy, J; Soutric, JL; Yasky, J, 1991) |
| "First-year results from the Treatment of Mild Hypertension Study (TOMHS) have demonstrated expected reductions in blood pressure for all antihypertensive agents studied." | ( Pool, JL, 1991) |
| "It is concluded that treatment of hypertension with a compound that lowers blood pressure and inhibits platelet activation may be of clinical benefit when routinely applied in hypertensive patients." | ( Fitscha, P; Rauscha, F; Sinzinger, H; Virgolini, I, 1991) |
| "These results indicate that long-term treatment of hypertension with alacepril induces regression of cardiac hypertrophy without any change in cardiac contractile function." | ( Hatanaka, T; Iwai, T; Nagano, M; Nakamura, I; Obara, Y; Takeda, N; Tanamura, A, 1991) |
| "A nonpharmacological approach in the treatment of mild hypertension is often advocated." | ( Aurell, M; Grimby, G; Holm, G; Krotkiewski, M; Szczepanik, J, 1991) |
| "The most frequently drug used in treatment of hypertension in Warsaw were beta-blockers and diuretics, whereas in the Tarnobrzeg province among men diuretic and composed drug preparations; women in the last region used frequently composed drug preparations and smooth muscle relaxants." | ( Broda, G; Burkiet, B; Idzior-Waluś, B; Kurjata, P; Kuźmińska, A; Pajak, A; Polakowska, M; Rywik, S; Sznajd, J; Szuba, K, 1990) |
| "Patients with untreated hypertension have been shown to be resistant to insulin-stimulated glucose uptake and are more hyperinsulinemic and hypertriglyceridemic than matched groups of patients with normal blood pressure." | ( Reaven, GM, 1991) |
| "To evaluate treatment of mild hypertension using combinations of diet and low-dose pharmacologic therapies." | ( Blaufox, MD; Davis, BR; Hawkins, CM; Knerr, MO; Langford, HG; Oberman, A; Swencionis, C; Wassertheil-Smoller, S, 1991) |
| "The Modern Approach to the Treatment of Hypertension (MATH) trial was conducted to determine the therapeutic safety and efficacy of the once-a-day nifedipine gastrointestinal therapeutic system (GITS) formulation in a large and diverse cohort of patients with mild-to-moderate hypertension." | ( Bravo, EL; Friedman, CP; Krakoff, LR; Tuck, ML, 1990) |
| "The Modern Approach to the Treatment of Hypertension (MATH) trial was conducted to determine the efficacy and safety of the new once-daily nifedipine gastrointestinal therapeutic system (GITS) formulation in a large cohort of mild-to-moderate hypertensive patients overall, and to identify specific effects of therapy in the presence of complicating factors such as diabetes and obesity." | ( Bravo, EL; Friedman, CP; Krakoff, LR; Tuck, ML, 1990) |
| "A satisfactory treatment of hypertension by these drugs may require the addition of diuretics and/or beta-blockers." | ( Haeusler, G, 1990) |
| "Both drugs are useful to treat hypertension, although NF has the drawback of a high dropout rate and CL induces abnormalities in biochemical parameters." | ( Calderón de la Barca Gázquez, JM; de Diego Cabrera, MS; González Santos, C; Iribarren Marín, MA; Martínez de la Iglesia, J; Pérula Torres, L, 1990) |
| "Captopril, a promising drug for the treatment of hypertension in diabetics, may influence sodium metabolism and adrenergic pathways." | ( Antonini, P; Beretta-Piccoli, C; Bernasconi-Zapf, M; Kressebuch, H; Pianezzi, F; Ziegler, WH, 1990) |
| "Enalapril is effective in the long-term treatment of hypertension; no loss of antihypertensive agents." | ( Cameron, A; Long, C; Mannering, D; Mondal, BK; Ranasinha, KW; Strouthidis, TM, 1990) |
| "Whereas there is no doubt that non-drug treatment of hypertension, and modifications in life-style to prevent an age-associated rise in arterial pressure are attractive concepts, opinions vary as to what advice should be offered to hypertensive patients and to populations at large." | ( Nicholls, MG, 1990) |
| "It is therefore important to treat hypertension in these patients with drugs which do not have negative effects on lipid-, glucose, or electrolyte-metabolism, and ACE inhibition fulfills these requirements." | ( Grönhagen-Riska, C, 1990) |
| "The ongoing Treatment of Mild Hypertension Study, now in its third year, has evaluated 847 patients to date with regard to lipid profile." | ( Schnaper, HW, 1990) |
| "Both drugs were effective in the treatment of hypertension." | ( Featherston, W; Gonzalez, DG; Kaplan, NM; Lugo, C; Ralakis, J; Ram, CV, 1990) |
| "A major risk associated with the acute treatment of severe hypertension is a reduction in cerebral blood flow (CBF) with ischemic injury to the central nervous system." | ( Brown, FD; Cervenka, K; Greene, CS; Gretler, DD; McCoy, CE; Murphy, MB, 1990) |
| "Successful long-term treatment of hypertension must include consideration of individual patients' life-style interfaced with the potential for adverse drug events." | ( Bannon, JA; Brennan, WK; Ross, AD; Schoenberger, JA; Testa, M, 1990) |
| "Twenty-seven patients with untreated hypertension and/or intermittent claudication received a bolus intravenous (i." | ( Freitag, B; Pointel, JP; Schmitt, C; Stoltz, JF; Voisin, P; Zannad, F, 1985) |
| "They also have great potential for the treatment of hypertension, cerebrovascular disorders, and Raynaud's phenomenon." | ( Brill, DM; Fozzard, HA, 1985) |
| "Nevertheless, treating essential hypertension with alpha blockade has always been attractive to investigators." | ( Laragh, JH, 1986) |
| "In the treatment of hypertension, drugs with different mechanisms of action are frequently combined." | ( Rahn, KH, 1987) |
| "Several drugs used in the treatment of hypertension have been shown to affect lipid metabolism." | ( Cortese, C; Ferrara, LA; Gnasso, A; Mancini, M; Marotta, T; Pasanisi, F, 1988) |
| "Clinical trials demonstrate that treatment of hypertension in the elderly reduces overall cardiovascular mortality, cardiac mortality, nonfatal cardiovascular events, congestive heart failure, progression to severe hypertension, and strokes." | ( Byyny, RL, 1989) |
| "A stepped-care approach to the treatment of hypertension has been developed to provide some practical guidelines for practicing physicians." | ( Brunner, HR; Nussberger, J; Waeber, B, 1987) |
| "Although treatment of hypertension per se is important, blood pressure alone may not explain the course of the hypertrophic process." | ( Corbett, J; Gonzalez, D; Kaplan, NM; Kulkarni, P; Ram, CV; Sunderajan, P; Taylor, A; Zachariah, NY, 1989) |
| "Fourteen patients with previously untreated essential hypertension and left ventricular hypertrophy were treated with a fixed-dose combination of acebutolol 200 mg and nifedipine 20 mg once daily for a followup of 25." | ( Behr, U; Franz, IW; Ketelhut, R; Tönnesmann, U, 1989) |
| "Long-term treatment of hypertension and CHF with lisinopril for at least 3 years confirms that the drug is well tolerated." | ( Cameron, HA; Higgins, TJ, 1989) |
| "We describe the case of a patient treated for hypertension with the angiotensin converting enzyme inhibitor enalapril, who developed hypotension after recovery from anaesthesia." | ( Jones, RM; Russell, RM, 1989) |
| "In 6 patients with untreated hypertension of mild or moderate degree, dilevalol was infused in the brachial artery." | ( Cleroux, J; Giannattasio, C; Grassi, G; Mancia, G; Seravalle, G; Zanchetti, A, 1989) |
| "The drug treatment of mild hypertension has been shown to afford protection against fatal and nonfatal strokes, congestive heart failure, progression to more severe levels of hypertension, and all-cause mortality, but not against the complications of coronary artery disease." | ( Davey, MJ, 1989) |
| "A number of agents are now available to treat hypertension." | ( Grimm, RH, 1989) |
| "In 16 patients with untreated primary hypertension of mild to moderate degree, we have evaluated the possible correlations between echocardiographic left ventricular mass (LVMe) and sympathetic nervous system activity, using pressor response to exogenous noradrenaline infusion, measurement of 24-h catecholamine urinary excretion and pressure response to ergometric exercise." | ( Capone, D; de Simone, G; Fasano, ML; Ferrara, LA; Mancini, M; Pisanti, N, 1989) |
| "In this study, treatment of mild hypertension with prazosin led to lower blood pressures and changes in insulin and lipoprotein metabolism that are important in this patient population." | ( Chen, YD; Hoffman, BB; Reaven, GM; Sheu, WH; Swislocki, AL, 1989) |
| "All patients were treated for hypertension with propranolol monotherapy." | ( Day, R; Goodfriend, TL; Hiatt, JG; Kochar, M; Schuna, AA; Vejraska, BD, 1989) |
| "The results indicated that men with untreated hypertension had significantly elevated plasma glucose (P less than ." | ( Hoffman, BB; Reaven, GM; Swislocki, AL, 1989) |
| "Nondrug treatments for hypertension can be classified into three categories: nutrition, exercise, or behavior modification." | ( Black, HR, 1989) |
| "Nifedipine has been used to treat acute hypertension and in many cases it has proved superior to other antihypertensive drugs." | ( Fauth, U; Halmágyi, M; Heinrichs, W; Karim, S; Tzanova, I, 1989) |
| "Ketanserin may be a useful treatment for hypertension following coronary artery surgery as it reduced arterial pressure without reflex tachycardia." | ( Colvin, JR; Hodsman, NB; Kenny, GN, 1989) |
| "Erythrocytes from patients with untreated essential hypertension (WHO I, II) and secondary hypertension were compared with those from normotensive subjects, and E." | ( Iwahashi, H; Kimura, K; Minatogawa, Y; Nishio, I; Shima, H; Takeda, J; Tsuda, K; Tsuda, S; Ura, M; Yoshikawa, H, 1988) |
| "After the treatment of hypertension with the ACE inhibitor the responses to exercise were less restrictive than those after treatment with the cardioselective beta-blocker." | ( Goodman, C; Radford, HM; Rogers, GG; Rosendorff, C, 1988) |
| "More effective treatment of hypertension is probably a major reason for the 45 percent decrease in stroke mortality rates in the last 12 years alone and for the dramatic decrease in the number of hypertensive patients in whom renal failure or congestive heart failure develops." | ( Moser, M, 1986) |
| "In the patients with untreated essential hypertension, nifedipine counteracted the lowering effect of AII on left ventricular ejection fraction (LVEF), which was 67." | ( Battler, A; Blau, A; Cohen, D; Eldar, M; Eliahou, HE; Iaina, A; Kapuler, S; Neufeld, HN; Rath, S, 1986) |
| "Pharmacological treatment of hypertension can, cause clinically significant alterations in endocrine function and glucose homeostasis." | ( Ehmer, B; Rudorf, J; van der Does, R, 1988) |
| "The use of spironolactone in the treatment of hypertension has been limited by the occurrence of sexual side effects, mainly menstrual disturbances in women and gynaecomastia in men." | ( Corvol, P; de Gasparo, M; Jeunemaître, X; Ménard, J; Preiswerk, G; Whitebread, SE, 1989) |
| "To be considered ideal for the treatment of hypertension, a class of drugs should produce a maintained reduction of arterial pressure primarily through a fall in total peripheral resistance that is at least uniformly distributed through the organ circulations of the target organs of hypertensive vascular disease." | ( Frohlich, ED, 1985) |
| "Optimum treatment of hypertension and angina pectoris with metoprolol is achieved through dose titration within the therapeutic range." | ( Benfield, P; Brogden, RN; Clissold, SP, 1986) |
| "Twenty-five patients with untreated essential hypertension (WHO I and II) were classified as those with and without asymmetric hypertrophy (with AH, n = 7; without AH, n = 18) by their echocardiographic patterns." | ( Arita, M; Fujiwara, S; Hamada, M; Hano, T; Masuyama, Y; Nishio, I; Ueno, Y, 1986) |
| "Thus, middle-aged men with untreated essential hypertension have an increased blood platelet release reaction related to their concentrations of atherogenic blood lipids." | ( Eide, IK; Foss, OP; Gjesdal, K; Kjeldsen, SE; Lande, K; Leren, P; Westheim, A, 1987) |
| "It should be useful in the treatment of hypertension, and, considering its pattern of cardiac actions, perhaps also as an after-load-reducing agent for the treatment of heart failure." | ( Hof, RP; Salzmann, R; Siegl, H, 1987) |
| "Patients with untreated essential hypertension had significantly higher plasma atrial natriuretic factor (ANF) levels (92." | ( Arai, H; Itoh, H; Kono, T; Morii, N; Mukoyama, M; Nakao, K; Saito, Y; Shiono, S; Sugawara, A; Yamada, T, 1988) |
| "Hydralazine treatment prevented hypertension in DOCA + HYD but did not prevent development of cardiac hypertrophy (heart weight/body weight of DOCA + HYD 3." | ( Anderson, PG; Bishop, SP; Digerness, SB, 1988) |
| "The prior treatment of hypertension was achieved by administration of hydroflumethiazide (120 mg/kg/day) and captopril (15-30 mg/kg/day) orally for 4-6 weeks by mixing in drinking water." | ( Inamura, K; Katayama, Y; Nagazumi, A; Shimizu, J; Soeda, T; Sugimoto, S; Suzuki, S; Terashi, A, 1986) |
| "During chronic treatment of hypertension in animals, the 5HT2 antagonistic properties, or a combination of 5HT2 and alpha 1-antagonistic effects, seems to be responsible for ketanserin's hypotensive action." | ( Hedner, T; Persson, B, 1988) |
| "Erythrocytes from patients with untreated essential hypertension were examined and compared with age-matched normotensive subjects." | ( Kimura, K; Masuyama, Y; Nishio, I; Shima, H; Takeda, J; Tsuda, K; Ura, M, 1988) |
| "Foridon is not indicated for the treatment of renal hypertension." | ( Demidiuk, VT; Mikunis, RI; Monastyrskiĭ, IuI; Pshelutskiĭ, FF; Serkova, VK, 1988) |
| "A randomised trial of the treatment of hypertension in 884 patients aged 60 to 79 years at the onset showed a reduction of 18/11 mm Hg in blood pressure over a mean follow up period of 4." | ( Coope, J; Warrender, TS, 1986) |
| "ISDN was successful in treating hypertension in 63% of the events, whereas NTG had an 83% success." | ( Barash, PG; Cahalan, M; Durkin, MA; Kaplan, J; Morris, RB; Thys, D, 1988) |
| "The prevalence of treated hypertension was 37." | ( Blanc, MM; Costa, G; Ebagosti, A; Jouve, A; Jouve, R; Serradimigni, A, 1988) |
| "Thus, diltiazem could be used for treatment of hypertension in diabetic patients." | ( Andrén, L; Dotevall, A; Eggertsen, R; Höglund, P; Olson, SO; Svensson, A; Wadenvik, H, 1988) |
| "In the treatment of hypertension nicardipine has been shown to be as effective as drugs such as hydrochlorothiazide, cyclopenthiazide, propranolol and verapamil in short term studies although confirmation of its long term usefulness in well-designed clinical trials is still required." | ( Clissold, SP; Sorkin, EM, 1987) |
| "Nonpharmacologic recommendations in the treatment of hypertension for which there appear to be sufficient requisite data include weight reduction for the obese, moderate sodium restriction (although this is controversial) and restriction of alcohol consumption to less than 57 g of ethanol daily." | ( Horan, MJ; Roccella, EJ, 1987) |
| "Other drugs are available that can treat hypertension with no or beneficial influence on blood lipids." | ( Kaplan, NM, 1988) |
| "The patients with untreated hypertension had higher [Ca2+]i values in non-activated platelets (P = 0." | ( Akerström, G; Hvarfner, A; Larsson, R; Ljunghall, S; Mörlin, C; Rastad, J; Wide, L, 1988) |
| "Nifedipine was administered to treat arterial hypertension (greater than 180 mm Hg, systolic)." | ( Sano, T; Suzuki, T; Takeshita, H; Tateishi, A; Tokuno, H, 1988) |
| "The efficacy of bromocriptine in the treatment of hypertension was assessed in a double-blind placebo controlled cross-over study preceded by a dose titration phase." | ( Bhattacharjee, P; Graham, B; Hernandez, J; Prichard, BN; Walden, RJ, 1986) |
| "Today, at a time when we often wish to treat mild hypertension, the goal is to have patients feel as well on treatment as they do off it." | ( Hollenberg, NK, 1987) |
| "22 patients with untreated, essential hypertension (diastolic blood-pressure greater than or equal to 140 mmHg) and in most cases also showing neurological symptoms were given a single oral dose of 400 mg labetalol." | ( Frithz, G, 1987) |
| "Forty-five patients with previously untreated hypertension and 33 hypertensive patients previously treated with thiazides until 1 month before allocation to the present treatments, completed the trial." | ( Bredesgaard, P; Johansen, P; Jørgensen, F, 1986) |
| "The ultimate goal in the treatment of hypertension is, of course, reduction of cardiovascular morbidity and mortality, but normalization of structural cardiovascular changes is clearly the second most important therapeutic goal." | ( Dahlöf, B, 1987) |
| "All patients were treated in the same hypertension clinic with the beta 1-selective agent atenolol, administered either alone or more usually with a diuretic with or without a vasodilator or other agents." | ( Cruickshank, JM; Pennert, K; Sörman, AE; Thorp, JM; Zacharias, FJ; Zacharias, FM, 1987) |
| "Nine patients who had been treated for hypertension for many years with atenolol in a dose of 100 mg/day took part in this 18-month study, during which the dosage alternated between 50 and 100 mg/day for two-month periods." | ( Aberg, H; Lithell, H; Selinus, I, 1986) |
| "Forty-four males with treated essential hypertension and a moderate-to-heavy alcohol intake participated in a randomized controlled crossover trial of the effects of varying alcohol intake on blood pressure control." | ( Beilin, LJ; Puddey, IB; Vandongen, R, 1986) |
| "Intravenous clonidine was used to treat systolic hypertension (systolic blood pressure greater than 160 mm Hg) in 15 patients with acute myocardial infarction and documented sympathetic overactivity (high plasma norepinephrine)." | ( Bernard, R; Liebens, I; Renard, M; Waterschoot, P, 1986) |
| "Sixteen patients were being treated for hypertension and three for fluid retention; five hypertensive patients were also taking non-steroidal anti-inflammatory drugs (NSAID)." | ( Bailey, RR; Low, WI; Lynn, KL; Sainsbury, R; Swainson, CP, 1985) |
| "The results show the possibility of treating essential hypertension with a low dose of a beta-adrenergic blocking agent in combination with 10 mg nifedipine." | ( Gfrerer, G; Gunselmann, W; Hennies, L; Hess, K; Lejeune, P; Rittgerodt, K; Schreiber, U; Winn, K, 1985) |
| "These results reveal the possibility of treating essential hypertension with a low dose of beta-adrenergic blocking agents in combination with 10 mg nifedipine." | ( Gfrerer, G; Gunselmann, W; Hoppe, I; Lejeune, P; Mummel, P; Petersen, B; Schreiber, U; Winkler, E, 1985) |
| "Nine patients with untreated essential hypertension (random blood pressure 173/109 +/- 14/7 mmHg) were studied before and after 16 weeks' treatment with oral nifedipine 10 mg three times a day." | ( Littler, WA; McLeay, RA; Stallard, J; Watson, RD, 1985) |
| "Now that the benefits of treating diastolic hypertension in the elderly have been convincingly proved, attention is turning to the need for, and the choice of, treatment of isolated systolic hypertension in this age group." | ( Gifford, RW, 1986) |
| "Initially, the pharmacologic treatment of hypertension consisted mostly of thiazide diuretics, since they were the only agents generally available that were well-tolerated by most patients." | ( Grimm, RH; Hunninghake, DB, 1986) |
| "In 25 patients with untreated essential hypertension and 25 healthy controls, erythrocyte intracellular Cl- concentration and activity as well as Na+ activity were measured." | ( Lange-Asschenfeldt, H; Losse, H; Vetter, H; Zidek, W, 1985) |
| "Fifteen patients were being treated for acute hypertension with SNP, and in five patients hypotension was induced with SNP to minimize blood loss." | ( Applebaum, RA; Farnum, M; Hufstedler, SM; Konchigeri, HN; Tremper, KK; Waxman, KS; Zaccari, J, 1985) |
| "Nonpharmacological treatment of hypertension relies on modifications in the diet and lifestyle." | ( Sloan, RS, 1985) |
| "Clonidine, a drug used to treat hypertension in man, readily reversed the high blood pressure and heart rate in this experimental model of hypertension." | ( Fuentes, JA; Naranjo, JR, 1985) |
| "Bromocriptine may be useful in the treatment of hypertension in patients with Parkinson's disease." | ( Chamontin, B; Montastruc, JL; Rascol, A, 1985) |
| "Ten patients with untreated essential hypertension were compared with 10 age- and sex-matched normotensive subjects." | ( Favre, L; Lew, PD; Vallotton, MB; Waldvogel, FA, 1985) |
| "Once daily treatment of hypertension with metoprolol, even in 'long-acting' formulations, cannot be recommended because of waning antihypertensive effect which would be missed at routine clinic attendance." | ( Freestone, S; Lennard, MS; Ramsay, LE; Silas, JH, 1985) |
| "In order to examine the effect of treatment of mild hypertension of the aged, a 4 year prospective trial was performed in 41 placebo and 38 drug-treated patients with an average age of 76." | ( Kuramoto, K; Matsushita, S, 1985) |
| "When used in the treatment of hypertension propranolol is at least of similar potency to bethanidine, guanethidine, and methyldopa." | ( Gillam, PM; Prichard, BN, 1969) |
| "Their current status in the treatment of hypertension, congestive heart failure, and these other conditions is reviewed." | ( Ferguson, RK; Rotmensch, HH; Vlasses, PH, 1984) |
| "Lastly, unlike many other forms of treatment for hypertension, renal blood flow and renal function tend to be maintained with converting enzyme inhibitors." | ( Johnston, CI, 1984) |
| "In patients with sustained untreated essential hypertension, brachial artery diameter is increased, blood flow is normal and arterial compliance is reduced independently of the level of blood pressure." | ( Bouthier, JD; Levenson, JA; Safar, AM; Safar, ME; Simon, AC, 1984) |
| "In contrast, in patients with untreated essential hypertension the increases in both plasma and red cell rubidium concentrations following the oral load were significantly enhanced." | ( Aronson, JK; Boon, NA; Grahame-Smith, DD; Hallis, KF; Raine, AE, 1984) |
| "Finally, a general schedule for the treatment of hypertension, issued as a guideline by the Dutch Institution of General Practitioners, is presented." | ( van Zwieten, PA, 1980) |
| "Women with previously untreated arterial hypertension have been followed up during ten years of beta-blocker treatment, first for three years with alprenolol and then for seven years with the selective beta1-blocker metoprolol." | ( Bengtsson, C, 1981) |
| "Doca-salt treatment caused hypertension and depletion of atrial NA in SBH, but had no effect on either blood pressure or atrial NA in SBN rats." | ( Ben-Ishay, D; Devynck, MA; Feurstein, G; Kobrin, I; Le Quan-Bui, KH; Zamir, N, 1981) |
| "Pindolol was also found effective in treating renal hypertension (Germany) and was considered particularly useful in hypertensive patients with coexistent angina pectoris (South Africa)." | ( Fanchamps, A, 1982) |
| "This new method for treating hypertension was convenient and well tolerated, and may increase patient compliance." | ( Brewer, DD; Drayer, JI; Lipson, JL; Weber, MA, 1984) |
| "During the Oslo Study on the treatment of mild hypertension, which was not specifically designed to study the effect on lipids, a decrease in serum high-density lipoprotein cholesterol and an increase in serum triglycerides was observed with a combination of propranolol and hydrochlorothiazide." | ( Leren, P, 1984) |
| "Pharmacological treatment of hypertension can cause clinically significant alterations in endocrine function through effects on glucose homeostasis, thyroid and parathyroid hormones, adrenal steroid metabolism and reproductive/pituitary physiology." | ( Brass, EP, 1984) |
| "Initial use of dopamine agonists in the treatment of hypertension and its possible involvement in the etiology and maintenance of hypertension are discussed." | ( Goldberg, LI, 1984) |
| "The results of the treatment in hypertension with pregnancy by a alpha-beta blocker in 58 women show: the good tolerance of the drug and its lack of teratogenic effect, its quasi-constant efficiency (91%) in hypertension, its benefit repercussion on neonatal weight." | ( Blazquez, G; Gérard, J; Giraud, P; Jeuffroy, A; Lardoux, H; Mounac, M, 1984) |
| "Diuretic drugs, when used in the treatment of hypertension, cause an increase in the serum concentration of total cholesterol and sometimes of triglyceride." | ( Ames, RP; Hill, P, 1982) |
| "Twenty-three 50-year-old men with untreated, essential hypertension had elevated plasma concentrations of the platelet release product beta-thromboglobulin (BTG) compared to 14 age-matched control men (p less than 0." | ( Aakesson, I; Amundsen, R; Eide, I; Foss, OP; Gjesdal, K; Kjeldsen, SE; Leren, P, 1983) |
| "In the management of severe treatment-resistant hypertension, the response to captopril (alone or in combination with a diuretic and/or propranolol) was better than the response to standard triple therapy." | ( Rosendorff, C, 1982) |
| "Most patients now starting treatment have mild hypertension and the benefits, although significant, are small (two deaths prevented per 1000 patient-years of treatment)." | ( Dollery, CT, 1983) |
| "Its role in the treatment of hypertension has previously been reviewed in this journal." | ( Brogden, RN; Kellerman, D; Romankiewicz, JA; Stanaszek, WF, 1983) |
| "In untreated essential hypertension, head-up tilt increased diastolic blood pressure, heart rate, and plasma norepinephrine." | ( Bravo, EL, 1983) |
| "To evaluate its usefulness in the treatment of hypertension in patients with coexisting chronic obstructive pulmonary disease (COPD), labetalol was administered in gradually increasing doses to a group of 11 patients with mild-to-moderate hypertension and COPD with a mild reversible component." | ( Burford, JG; Conrad, SA; George, RB; Kinasewitz, GT; Manocha, K, 1983) |
| "Nine patients with untreated essential hypertension (mean casual blood pressure 173/109 +/- 14/7 mm Hg) (+/- SD) were studied in the control state and after 16 weeks of treatment with nifedipine, 10 mg orally every 8 hours." | ( Littler, WA; McLeay, RA; Stallard, TJ; Watson, RD, 1983) |
| "Clinical experience in the treatment of hypertension with this class of agents is confined to verapamil, nifedipine, and diltiazem." | ( Frishman, WH; Ocken, S; Spivack, C, 1983) |
| "Thirteen of the patients had drug treatment for hypertension." | ( Karttunen, P; Tuomilehto, J; Uusitupa, M; Wolf, E, 1984) |
| "Sixty-five out-patients on drug treatment for hypertension but with diastolic blood pressures greater than 95 mm Hg on two successive occasions were randomly allocated either to an index group on a 1 g Na (44 mmol) daily diet or to a reference group." | ( Bulpitt, CJ; Bulpitt, PF; Daymond, M; Dollery, CT; Ferrier, G; Harrison, R; Lewis, PJ, 1984) |
| "Mg may also be important in drug treatment of hypertension and diuretics may result in enhanced losses of magnesium." | ( Brady, HR; Ryan, MP, 1984) |
| "Those patients receiving long term treatment for their hypertension who continued to take thiazides had persistent hypokalaemia and hyperuricaemia." | ( Thomas, JP; Thomson, WH, 1983) |
| "The efficacy of nifedipine in the treatment of hypertension was assessed in 15 patients whose hypertension continued while being treated with atenolol 100 mg and bendrofluazide 5 mg daily." | ( Dollery, CT; Murphy, MB; Scriven, AJ, 1983) |
| "Atenolol can be used cautiously to treat hypertension in asthmatic patients under certain conditions." | ( Clement, S; Grizotzki, B; Krauss, A; Krauss, S; Spitz, E, 1984) |
| "Beta blockers are now widely used to treat hypertension during pregnancy." | ( Dubois, D; Klepper, A; Leboullenger, P; Petitcolas, J; Temperville, B, 1984) |
| "Ten males with previously untreated essential hypertension in WHO stage I, aged 35-55 years, were studied on an outpatient basis." | ( Lund-Johansen, P, 1984) |
| "Ten patients with untreated essential hypertension were compared to 10- age and sex-matched normotensive subjects." | ( Favre, L; Lew, PD; Vallotton, MB, 1984) |
| "These compounds could be useful in the treatment of hypertension as hypothalamic dopaminergic dysfunction has recently been suggested in these patients." | ( Elghozi, JL, 1983) |
| "Thiazide diuretics used alone to treat hypertension can cause hypokalaemia in a substantial proportion of patients." | ( Poole-Wilson, PA, 1983) |
| "Indapamide is safe and effective for treatment of hypertension in mild to severe renal impairment, but advantages over furosemide are questionable." | ( Conner, CS, 1983) |
| "Fifteen males with previously untreated essential hypertension in WHO stage I, aged 20-64 years were studied on an outpatient basis." | ( Lund-Johansen, P; Omvik, P, 1983) |
| "Care must be taken in treating hypertension in diabetic patients because the choice of antihypertensive agent may worsen the diabetic state or its complications or cause additional health problems for the patient." | ( Lipson, LG, 1984) |
| "Clonidine-treated hypertension was associated with decreased (0." | ( Kauppila, A; Puolakka, J; Vuori, J, 1984) |
| "In the treatment of severe hypertension the choice of vasodilator is limited by side-effects, of which the lupus erythematosus syndrome induced by hydralazine is potentially the most serious, particularly in patients with the slow acetylator phenotype." | ( Donnelly, RJ; Elliott, HL; McLean, K; Reid, JL; Sumner, DJ, 1982) |
| "Programmes for the treatment of hypertension are a major therapeutic challenge." | ( Seedat, YK, 1982) |
| "After an explanation of the treatment of hypertension the results of a clinical study using the combination product Cardiotensin are presented." | ( Petersmann, H, 1980) |
| "Labetalol has been successful in treating hypertension, and few side effects have been reported, although there have been cases of muscle pain during treatment." | ( Kissin, E; Rosenthal, T; Sarova, I; Teicher, A, 1981) |
| "In eight subjects with untreated essential hypertension, blood pressure was monitored intraarterially and the effects of baroreceptor stimulation or deactivation were assessed by measuring (1) the slopes of the relations between increase or reduction in systolic pressure (intravenous phenylephrine or nitroglycerin) and the resulting lengthening or shortening in R-R interval, and (2) the increase or decrease in mean arterial pressure induced by increasing and decreasing carotid transmural pressure (neck chamber)." | ( Bertinieri, G; Buccino, N; Ferrari, A; Grassi, G; Gregorini, L; Mancia, G; Parati, G; Pomidossi, G; Rupoli, L; Zanchetti, A, 1982) |
| "Labetalol seems to be suitable to treat hypertension perioperatively in neurosurgical patients but it is not a suitable drug for induced hypotension." | ( Anger, C; Hidding, J; Lawin, P; Puchstein, C; van Aken, H, 1983) |
| "Labetalol was used to treat systemic hypertension (systolic blood pressure above 150 mmHg) in 11 patients with acute myocardial infarction; its haemodynamic effects and tolerance were studied." | ( Bernard, R; Jacobs, P; Renard, M; Rivière, A, 1983) |
| "Other events, such as medical treatment of hypertension or changes in the case fatality rate, could have contributed to the decline in stroke mortality." | ( Cummins, RO, 1983) |
| "Nine patients with untreated, essential hypertension (mean casual blood pressure 173/109 +/- 14/7 mmHg (+/- s." | ( Littler, WA; McLeay, RA; Stallard, TJ; Watson, RD, 1983) |
| "Although drug treatment of hypertension is associated with improved survival and decreased vascular complications, drug compliance is a major problem in the control of hypertension." | ( Freed, CR; Gerber, JG; Nies, AS, 1980) |
| "Captopril was given for treatment of hypertension alone or in combination with diuretics to 32 patients for 1- to 4-mo periods." | ( Hata, T; Iwanaga, K; Kumahara, Y; Maruyama, A; Mikami, H; Naka, T; Nakamaru, M; Ogihara, T, 1980) |
| "Urapidil was found effective in the treatment of hypertension during extracorporeal circulation." | ( Barankay, A; Göb, E; Richter, JA, 1981) |
| "There is little excuse for not treating hypertension, including mild hypertension." | ( Kannel, WB, 1981) |
| "In 16 fo 20 patients with treatment-resistant hypertension endralazine, combined with beta-receptor blockers and diuretics, significantly lowered mean arterial blood pressure from 198/112 mmHg to 148/88 mmHg." | ( Glöckner, WM; Kindler, J; Konrads, A; Meurer, KA; Schulz, V; Sieberth, HG; Vaith, P, 1981) |
| "Beta-blockers are now well established treatment for hypertension." | ( Almatsier, M; Ranakusuma, TA; Soemargo, S; Tobing, SM, 1981) |
| "2 Seven subjects with untreated essential hypertension were studied before and 2 months after commencing treatment with propranolol LA once daily in the morning, results showing that smooth control of blood pressure and heart rate occurred throughout 24 h." | ( Balasubramanian, V; Craig, MW; Mann, S; Raftery, EB, 1980) |
| "Sixty women not on treatment for hypertension were selected from a defined population and examined, applying the duplicate portion technique, with respect to the relationships between BP and the intake of energy and nutrients." | ( Abdulla, M; Akesson, B; Dencker, I; Jägerstad, M; Melander, A; Nordén, A; Scherstén, B; Thulin, T, 1980) |
| "In a large group of patients with untreated hypertension, excretion rates of tetrahydrocorticosterone (THB), allotetrahydrocorticosterone (alloTHB) and tetrahydro-11-dehydrocorticosterone (THA) were all significantly higher than in a group of matched normotensive controls." | ( Fraser, R; Glorioso, N; Ingram, MC; Soro, A; Tonolo, G, 1995) |
| "78 persons with untreated hypertension recruited from a population survey." | ( Bønaa, KH; Ingebretsen, OC; Jenssen, T; Nordøy, A; Toft, I, 1995) |
| "Cilazapril is an effective treatment for hypertension in this model of progressive renal disease and may have benefits beyond the prevention of cardiovascular morbidity." | ( Ogborn, MR; Pinette, G; Sareen, S, 1995) |
| "An important role for diuretics in the treatment of hypertension is assured on the basis of the latest randomized, prospective trials." | ( Luft, FC, 1993) |
| "Studies in animals suggest that treatment of hypertension may restore the nitric oxide system towards normal." | ( Calver, A; Collier, J; Vallance, P, 1994) |
| "In the patients with treated essential hypertension, at the same doses, noradrenaline and L-NMMA also produced similar reductions in forearm blood flow." | ( Calver, A; Collier, J; Vallance, P, 1994) |
| "These results suggest that treatment of hypertension may restore NO mediated vasodilatation towards normal." | ( Calver, A; Collier, J; Vallance, P, 1994) |
| "After capsaicin treatment, 1K-WRAP hypertension was induced by removing the right kidney and wrapping the left kidney with a figure-8 ligature." | ( Burg, M; Knuepfer, MM; Zahm, DS, 1994) |
| "Having acknowledge the need to treat arterial Hypertension concomitantly effective, safe and easy to comply with." | ( Baptista, A; Rocha, E; Serra-Pinto, L, 1995) |
| "Diuretics are widely prescribed to treat hypertension and oedema." | ( Ferner, RE; Lip, GY, 1995) |
| "The effects of perindopril treatment on hypertension development and the lifespan of adult spontaneously hypertensive rats (SHR) were studied." | ( Delaney, KH; Lee, RM; Lu, M, 1995) |
| "Altogether, 17 patients with untreated primary hypertension were examined together with matched, healthy and normotensive controls with normal body-mass index." | ( Frithz, G; Ronquist, G; Scherstén, T; Soussi, B; Waldenström, A, 1995) |
| "The compound is used in the treatment of hypertension, primarily in the elderly." | ( Amenta, F; Sabbatini, M; Strocchi, P, 1995) |
| "Fourteen subjects with untreated essential hypertension were subjected to 2-h water immersion (WI) study." | ( Coruzzi, P; Mossini, GL; Musiari, L; Novarini, A, 1993) |
| "The drug is equally effective in treating hypertension in elderly and younger patients and does not appear to adversely affect glucose or lipid metabolism." | ( Brogden, RN; McTavish, D, 1995) |
| "In the treatment of hypertension in renally impaired patients, normalization of blood pressure alone may not be sufficient to prevent significant morbidity to the kidneys." | ( Frishman, WH, 1994) |
| "Subjects had medically treated essential hypertension for a minimum of 10 years (range = 10 to 24 yr) with no evidence of end-organ impairment from hypertension by routine clinical screening and by history." | ( Gonzalez-Aviles, A; Grady, C; Mentis, M; Rapoport, SI; Salerno, JA; Schapiro, MB; Wagner, E, 1995) |
| "ABPM is useful in the diagnosis and treatment of hypertension in children with end-stage renal disease." | ( Busch, C; Lemmer, B; Lingens, N; Loirat, C; Schärer, K; Soergel, M, 1995) |
| "Animal data suggest that treatment of hypertension may restore normal NO-mediated responses." | ( Benjamin, N; Lyons, D; Webster, J, 1994) |
| "ACE inhibitors are used world-wide for treatment of hypertension and cardiac failure; liver damage is a rare but potentially severe side-effect of these drugs." | ( de Vries, RA; Droste, HT, 1995) |
| "To study treatment of hypertension in pregnancy in Sweden and compare our results with a similar study published in 1981." | ( Ingemarsson, I; Montal, S; Wide-Swensson, D, 1994) |
| "The main target organ in untreated arterial hypertension (HTA) is the blood vessel wall (BVW) of the high pressure system (conductance and resistance arteries), which is primarily responsible for vital organ integrity." | ( Plante, GE, 1994) |
| "To study the effect of perindopril treatment on hypertension and stroke prevention in two genetic models of hypertensive rats." | ( Lee, RM; Smeda, JS; Wang, H, 1994) |
| "10 with mild uncomplicated and untreated essential hypertension, 10 with essential hypertension under chronic treatment with captopril, 50 mg bid, and 10 with essential hypertension under chronic treatment with atenolol, 100 mg oid, received aspirin, 100 mg oid, and the corresponding placebo for one month, according to a double blind randomized cross-over design." | ( Abdel-Haq, B; Favilla, S; Magagna, A; Salvetti, A; Taddei, S, 1994) |
| "The aim of this trial was to study the treatment of hypertension in the elderly, comparing a new oxazoline antihypertensive agent, rilmenidine, with the diuretic hydrochlorothiazide (HCZ)." | ( Corcoran, C; Coupez, G; Creytens, G; Opsomer, M; Pelemans, W; Van Dessel, A; Verhaeghe, J, 1994) |
| "Patients with documented and treated hypertension (systolic and diastolic blood pressure: 141 +/- 18 and 82 +/- 9 mmHg) exhaled 13." | ( Geroulanos, S; Guggenbach, M; Gyurech, D; Holzer, P; Marathia, K; Schilling, J, 1994) |
| "However, the treatment of hypertension in older patients is often complicated by the presence of concomitant disorders." | ( Lessem, JN; Weber, MA, 1993) |
| "It is concluded that the transdermal treatment of hypertension with a clonidine containing transdermal system is therapeutically effective and probably associated with a high acceptability and increased compliance." | ( , 1993) |
| "Effective treatment of hypertension in renal disease, particularly with converting enzyme inhibitors, is capable of slowing the rate of loss of function, both in animal models and in human disease, though in the latter case this benefit has so far been demonstrated unequivocally only in patients with diabetic nephropathy." | ( Raine, AE, 1994) |
| "In general the negative attitudes to treating hypertension in the elderly can no longer be upheld, although in certain sub-groups the benefits of treatment are as yet unproven." | ( Potter, JF, 1994) |
| "The prevalence of treated hypertension was higher (p < 0." | ( Bengtsson, BA; Edén, S; Larson, G; Rosén, T; Wilhelmsen, L, 1993) |
| "Increasing concern over long-term drug treatment of mild hypertension has stimulated several studies of weight reduction." | ( Blaufox, MD; Cutler, JA; Davis, BR; Kirchner, K; Langford, HG; Oberman, A; Wassertheil-Smoller, S; Zimbaldi, N, 1993) |
| "It is now well accepted that treatment of hypertension must extend beyond the mere control of blood pressure." | ( Bartenbach, S; Gohlke, P; Kuwer, I; Lamberty, V; Schnell, A; Unger, T, 1993) |
| "The impact of treating hypertension on coronary artery disease has been less than anticipated from epidemiologic studies of cardiovascular risk factors." | ( Carruthers, G; Dessain, P; Fodor, G; Newman, C; Palmer, W; Sim, D, 1993) |
| "Non drug treatment of hypertension is being given increasing attention." | ( Beard, TC; Gordon, RD, 1993) |
| "Hydralazine has been widely used in treatment of hypertension in eclampsia and preeclampsia, and its safety has been demonstrated in these patients." | ( Abdelwahab, W; Frishman, W; Landau, A, 1995) |
| "Low-dose L-NAME treatment induced hypertension only when associated with sodium overload." | ( De Nucci, G; Fujihara, CK; Malheiros, DM; Sassaki, AL; Yamada, SS; Zatz, R, 1996) |
| "The most important measures in dietary treatment of hypertension are: salt restriction, lowering body weight in obesity, decreasing alcohol consumption." | ( Zidek, W, 1996) |
| "Twenty-six patients with previously untreated essential hypertension took enalapril 20 mg twice daily for 5 years." | ( Amaro Gendón, A; Calvo Gómez, C; Castelo Fuentes, V; García Acuña, JM; Gil de la Peña, M; González-Juanatey, JR; Pose Reino, A, 1995) |
| "Sixty-three patients with untreated essential hypertension were randomly assigned in a placebo-controlled crossover comparison to atenolol 50 mg once daily, lisinopril 10 mg once daily and nifedipine SR 20 mg twice daily, and the effect on blood pressure was assessed by ambulatory blood pressure monitoring (ABPM)." | ( Bird, R; Casadei, B; Conway, J; Dudley, C; Keavney, B; Ratcliffe, P, 1996) |
| "Twenty patients with previously untreated hypertension who consecutively attended our outpatient hypertension clinic were included in this prospective, open, cross-over study." | ( Danielson, BG; Hägg, A; Linde, T; Mörlin, C; Sandhagen, B, 1996) |
| "A variety of therapies is available for treatment of hypertension in patients with metabolic complications." | ( Corry, DB; Tuck, ML, 1996) |
| "Patients with previously untreated diastolic hypertension were treated with antihypertensive drugs for one year; these were withdrawn in patients with well controlled blood pressure, who were then followed for one year." | ( Beltman, FW; de Graeff, PA; Havinga, TK; Heesen, WF; Kok, RH; Lie, KI; May, JF; Meyboom-de Jong, B; Schuurman, FH; Smit, AJ; van der Veur, E, 1996) |
| "Improved detection and treatment of hypertension is needed to slow the progression of renal disease in nondiabetics and diabetics, together with screening and treatment protocols for albuminuric diabetic patients." | ( Hoy, W; Jim, S; Light, A; Megill, D; Warrington, W, 1996) |
| "The data suggested that doxazosin treatment of hypertension attenuated much of the abnormalities of insulin resistance but had little effect on insulin-sensitive patients." | ( Huang, SH; Jeng, CY; Jeng, JR; Sheu, WH; Shieh, SM, 1996) |
| "These drugs, widely used in the treatment of hypertension, prevent the formation of angiotensin II and the generation of free radicals, as well as the hydrolysis of bradykinin, enkephalins and endorphins." | ( Govantes, C; Marín, J, 1996) |
| "Thiazide diuretics are commonly used to treat hypertension because of their demonstrated efficacy, favorable safety profile, low acquisition cost, and their proven ability to reduce blood pressure-related morbidity and mortality." | ( Cushman, WC; Flack, JM, 1996) |
| "These drugs may be recommended for the treatment of hypertension in patients with type 2 (non-insulin-dependent) diabetes." | ( Czyzyk, A; Jasik, M; Kasperska-Dworak, A, 1996) |
| "Six were treated for hypertension." | ( Andereassen, AK; Berg, KJ; Geiran, O; Hartmann, A; Holdaas, H; Simonsen, S, 1996) |
| "Use of enalapril is safe in the treatment of hypertension in dialysis patients." | ( Lai, KN; Lam, WK; Li, KT; Lui, SF; Nicholls, MG; Wong, KC; Woo, KS, 1995) |
| "Despite 63/77 (82%) being treated for hypertension, only 20 (26%) were controlled (< 140/< 90 mm Hg)." | ( Anapol, H; Materson, BJ; Preston, RA; Yoham, MA, 1996) |
| "Reasons for discontinuing treatment were hypertension, five; cardiac failure, four; depression, three; oedema, three; and unspecified, two." | ( Hussain, RM; Kenny, RA; Lawson, J; McIntosh, SJ, 1996) |
| "Drugs to treat hypertension must not only reduce blood pressure, but also modify the facts which lead to ventricular hypertrophy." | ( Hoyos, M; Justo, E; Moreno, R; Oliván, J; Pérez Cano, R; Pizarro, JL; Ramos, E; Rodríguez, A, 1996) |
| "Nifedipine is a commonly used agent in treating hypertension and angina because of its vasodilator properties." | ( Cunningham, SK; Fiad, TM; Hayes, FJ; McKenna, TJ, 1997) |
| "It is urgent to treat hypertension in these patients with drugs that do not further impair glucose control." | ( Lithell, HO, 1997) |
| "Eighteen subjects had untreated essential hypertension, and 10 were normotensive." | ( James, MA; Potter, JF; Swales, JD; Thurston, H; Watt, PA, 1997) |
| "Aggressive treatment of hypertension is therefore essential in early lupus nephritis in order to prevent further deterioration of renal function as the disease evolves." | ( Chrystal, V; Naiker, IP; Randeree, IG; Seedat, YK, 1997) |
| "Seventy-eight persons with untreated hypertension were included in a 16-week, double-blind, randomized, controlled intervention study with 4 g/d of eicosapentaenoic and docosahexaenoic acids or corn oil placebo." | ( Bønaa, KH; Ingebretsen, OC; Jenssen, T; Nordøy, A; Toft, I, 1997) |
| "Safety in the drug treatment of hypertension can only be seen in relation to efficacy, which has now come to mean not just blood pressure (BP) reduction but improvements in hard end points including mortality." | ( Opie, LH, 1997) |
| "Twenty-one were attending for treatment of hypertension and 17 were normotensive, attending for minor gastrointestinal complaints." | ( Galley, HF; Howdle, PD; Thornton, J; Walker, BE; Webster, NR, 1997) |
| "Centre for Prevention, Diagnosis and Treatment of Hypertension in Pregnancy, University of Turin, Italy." | ( Benedetto, C; Carandente, F; Chiarolini, L; Giarola, M; Maulà, V; Zonca, M, 1997) |
| "The consequences of untreated hypertension include myocardial infarction, stroke, congestive heart failure, peripheral vascular disease and renal disease." | ( Dubois, M; Wilson, TW, 1997) |
| "Indeed, drug treatment of hypertension with hydralazine does reduce blood pressure but not cardiovascular hypertrophy." | ( Ghisdal, P; Godfraind, T; Morel, N; Salomone, S, 1997) |
| "History of untreated hypertension prior to the initial stroke (RR = 1." | ( Baranska-Gieruszczak, M; Czlonkowska, A; Hier, DB; Lechowicz, W; Ryglewicz, D, 1997) |
| "Children attending the above centre for treatment of hypertension." | ( Dillon, MJ; Goonasekera, CD; Rees, DD; Shah, V, 1997) |
| "Therefore, it is very important to treat hypertension to reduce cardiovascular events as well as end-stage renal disease." | ( Katayama, S, 1997) |
| "Baseline data from the Treatment of Mild Hypertension Study (TOMHS) was used to assess differences in the urinary excretion of sodium and potassium, and the Na:K ratio between black and white participants, and also to explore the relationship of socioeconomic status (SES) and urinary electrolyte excretion within each ethnic group." | ( Elmer, PJ; Flack, JM; Ganguli, MC; Grandits, GA; Grimm, RH; Svendsen, KH, 1997) |
| "Evidence shows that treating hypertension effectively can have a major beneficial impact on some, but not all, forms of adult cardiovascular disease." | ( Deedwania, PC, 1997) |
| "Four-week DOCA-salt treatment induced hypertension associated with cardiac hypertrophy." | ( Fareh, J; Schiffrin, EL; Thibault, G; Touyz, RM, 1997) |
| "Eighteen previously untreated primary hypertension patients were selected for therapy either with 50-250 mg/day metoprolol (n = 11) or with 3-20 mg/day prazosin (n = 8)." | ( Gretzer, I; Hjemdahl, P, 1997) |
| "L-NAME treatment induced hypertension that was associated with increased plasma renin activity." | ( Brosnan, MJ; Devlin, AM; Dominiczak, AF; Graham, D; Hamilton, CA; McIntyre, M; McPhaden, AR; Morton, JJ; Reid, JL, 1998) |
| "Perindopril in treatment hypertension effectively reduces the level of blood pressure (systolic, diastolic and mean) without any effect on heart rate." | ( Cholewa, M; Cwetsch, A; Kamiński, G; Kubik, L; Skrobowski, A, 1997) |
| "MIBEFRADIL IN THE TREATMENT OF HYPERTENSION: The antihypertensive efficacy of mibefradil, a new selective transient (T)-channel calcium antagonist, was studied in eight randomized, double-blind, parallel-design trials: four placebo-controlled and four active drug-controlled versus other calcium antagonists." | ( Kobrin, I, 1997) |
| "For the treatment of hypertension, the combination of an angiotensin-converting enzyme (ACE) inhibitor and a thiazide diuretic is supported by multiple lines of evidence, because these drugs have synergistic action and are expected to cancel out each other's adverse side effects." | ( Doi, Y; Domae, A; Ebihara, A; Ishimitsu, T; Kimura, M; Murata, K; Sagara, E; Sakamaki, T; Shibata, A; Sugishita, Y; Yagi, S, 1997) |
| "L-NAME treatment induced hypertension (systolic blood pressure control 129." | ( Arribas, SM; Dominiczak, AF; González, C; Graham, D; McGrath, JC, 1997) |
| "During glucocorticoid treatment, hypertension was corrected in all." | ( Gartside, MG; Gordon, RD; Stowasser, M; Taylor, WL; Tunny, TJ, 1997) |
| "use of urapidil in the treatment of hypertension in pregnancy unresponsive to dihydralazine and one report which describes the oral use of urapidil." | ( Bastert, G; Wacker, J; Walter-Sack, I; Werner, P, 1998) |
| "The results from the Prevention and Treatment of Hypertension Study (PATHS) do not provide strong support for reducing alcohol consumption in nondependent moderate drinkers as a sole method for the prevention or treatment of hypertension." | ( Allender, PS; Bingham, SF; Burg, M; Collins, JF; Cushman, WC; Cutler, JA; Dubbert, P; Dufour, M; Felicetta, JV; Follmann, D; Hamburger, RJ; Hamilton, BP; Hanna, E; Harford, T; Katz, LA; Kirk, GF; Lakshman, R; Perry, HM; Walsh, SM; Willenbring, ML, 1998) |
| "It is expected that the treatment of hypertension in patients with renal disease decreases the risk of cardiovascular events, but the evidence in these patients is lacking." | ( Applegate, WB; Bailey, JE; Cushman, WC; Elam, JT; Ferrucci, L; Pahor, M; Shorr, RI; Somes, GW, 1998) |
| "In clinical practice, the treatment of hypertension in pregnancy may be delayed until the hypertension becomes severe." | ( , 1998) |
| "The benefit of treating hypertension has been proven, but cardiovascular morbidity and mortality rates remain high." | ( Julius, S; Mann, J, 1998) |
| "Indications for treatment were hypertension (75%), coronary artery disease with (12%) or without (3%) hypertension, or unknown (10%)." | ( Danser, AH; Hense, HW; Holmer, SR; Mayer, B; Riegger, GA; Schunkert, H, 1998) |
| "The recommended doses for treatment of hypertension and chronic stable angina pectoris are 50 or 100 mg." | ( Welker, HA, 1998) |
| "In the treatment of hypertension, nitroprusside and nitrates exert their actions via NO donation." | ( Dillon, MJ; Goonasekera, CD, 1998) |
| "The main goal of the treatment of hypertension is to decrease cardiovascular morbidity and mortality." | ( Heemann, U; Philipp, T, 1998) |
| "However, the frequency with which treated primary hypertension leads to renal failure is not known." | ( Andersson, OK; Ljungman, S; Siewert-Delle, A; Wilhelmsen, L, 1998) |
| "To determine if treated primary hypertension can lead to ESRD, we studied the development of serum creatinine levels in 686 white hypertensive men, recruited from a random third of the male population aged 47-55 years living in Göteborg, Sweden (n=9998; 7495 participants)." | ( Andersson, OK; Ljungman, S; Siewert-Delle, A; Wilhelmsen, L, 1998) |
| "Baseline data from the Treatment of Mild Hypertension Study (TOMHS) was used to assess urinary Na and K excretion profiles by race, clinic geographic area, and education." | ( Elmer, PJ; Flack, JM; Ganguli, MC; Grandits, GA; Grimm, RH; Svendsen, KH, 1999) |
| "It has been reported that insulin treatment improves hypertension in patients with diabetes mellitus." | ( Gonda, T; Kato, Y; Kawaguchi, M; Koshimura, K; Murakami, Y; Tsumori, M, 1999) |
| "Patients with newly discovered, never-treated, sustained hypertension were included in the study after a 1 month run-in, during which time their blood pressure was measured three times at 2 week intervals." | ( Celentano, A; Crivaro, M; Ferrara, LA; Gaeta, I; Guida, L; Iannuzzi, R; Marotta, T; Pasanisi, F, 1999) |
| "For the treatment of hypertension, the following recommendations are made." | ( Bolli, P; Burgess, E; Chockalingam, A; Cutler, H; Hamet, P; Lewanczuk, R; Taylor, G, 1999) |
| "In addition to their treatment of hypertension, ACE inhibitors are recognized as being effective in the management of heart failure, left ventricular hypertrophy, recurrent myocardial infarctions, and renal disease." | ( Ingenito, AJ; McConnaughey, JS; McConnaughey, MM, 1999) |
| "People treated for hypertension had nonsignificant odds ratios whatever the RHR categories." | ( Ferrières, J; Ruidavets, JB, 1999) |
| "More patients are being treated for hypertension, but blood pressures are not decreasing to target levels." | ( Neutel, JM, 1999) |
| "We still do not have an ideal drug to treat acute severe hypertension in pregnancy." | ( Mabie, WC, 1999) |
| "Current guidelines on the treatment of hypertension continue to emphasise the use of low dose diuretics as appropriate first-line therapy whenever pharmacological intervention is indicated, except where there are positive indications (e." | ( Hansson, L, 1999) |
| "Further studies of ascorbic acid to treat hypertension, with clinical endpoints, are warranted." | ( Duffy, SJ; Frei, B; Gokce, N; Holbrook, M; Huang, A; Keaney, JF; Vita, JA, 1999) |
| "We studied the effect of dihydralazine treatment of hypertension in spontaneously hypertensive stroke-prone rats in a model of permanent focal cerebral ischemia (stroke)." | ( Dirnagl, U; Einhäupl, KM; Harms, H; Megow, D; Prass, K; Wiegand, F, 2000) |
| "Therefore, for the treatment of hypertension it is important to understand the mechanism of cardiac hypertrophy and to establish effective pharmaceutical interventions." | ( Komuro, I; Yamazaki, T; Yazaki, Y, 1999) |
| "Twenty patients with untreated hypertension were classified into two groups: dippers (n = 9) and nondippers (n = 11)." | ( Ijiri, H; Ishihara, T; Kohno, I; Komori, S; Sano, S; Sawanobori, T; Takusagawa, M; Tamura, K; Yin, DF, 2000) |
| "Selection of beta-blockers for treatment of hypertension should be based on other factors." | ( Acree, M; Baron, RB; Coates, TJ; Gardiner, PS; Halliday, R; Hauck, WW; Pérez-Stable, EJ, 2000) |
| "When diagnosing or evaluating treatment in hypertension, this may have implications." | ( Enström, I; Lindholm, LH; Pennert, K, 2000) |
| "While nitroprusside is commonly used to treat severe hypertension, it is an extremely toxic drug that should only be used in rare circumstances." | ( Marik, PE; Varon, J, 2000) |
| "Ramipril is indicated in the treatment of hypertension, congestive cardiac failure (including that following acute myocardial infarction), nephropathy (with and without diabetes mellitus) and now, following the findings of the HOPE study, in the prevention of cardiovascular events (including myocardial infarction) in high risk individuals." | ( Ball, SG; Smith, WH, 2000) |
| "We conclude that the treatment of hypertension by combined therapy leads to a better normalisation of structural, contractile, and metabolic parameters in the SHR, than either treatment alone and that metabolic changes with the pathology are resolved with appropriate therapy." | ( Boehm, EA; Clark, JF; Radda, GK, 2000) |
| "Calcium antagonists are a first-line treatment for hypertension." | ( Dahlöf, B; de Faire, U; Hansson, L; Hedner, T; Karlberg, BE; Kjeldsen, SE; Lanke, J; Lindholm, LH; Lund-Johansen, P; Syvertsen, JO, 2000) |
| "Prevention is an important goal in the treatment of hypertension." | ( Julius, S; Nesbitt, SD, 2000) |
| "Calcium antagonists are used to treat hypertension because, owing to their mechanism of action, they can provoke systemic, as well as coronary vasodilatation." | ( Luca, S; Terranova, R, 2000) |
| "Thirty-two patients with untreated hypertension (BP 168/96) had significantly lower levels of both MMP-9 and TIMP-1 when compared to 24 matched normotensive controls (BP 123/80) (P<0." | ( Beevers, DG; Blann, AD; Edmunds, E; Li-Saw-Hee, FL; Lip, GY, 2000) |
| "The purpose of treating hypertension is prevention of cardiovascular diseases." | ( Ellekjaer, H; Gjelsvik, B; Hetlevik, I; Holmen, J; Kimsås, A; Meland, E, 2000) |
| "The prevention and treatment of hypertension both from the viewpoint of individual patient care and in terms of population health presents a considerable challenge to the medical profession." | ( Grassi, G; Mancia, G, 2000) |
| "In men, treated hypertension (OR, 2." | ( Hillbom, M; Juvela, S; Saloheimo, P, 2001) |
| "Other independent risk factors are untreated hypertension, previous ischemic stroke, epilepsy, and recent strenuous physical exertion." | ( Hillbom, M; Juvela, S; Saloheimo, P, 2001) |
| "Medical treatment of severe hypertension in pregnancy is required." | ( Bolte, AC; Dekker, GA; van Geijn, HP, 2001) |
| "There is no consensus on how best to treat hypertension among those with diabetes." | ( Barzilay, JI; Basile, JN; Ciocon, JO; Davis, BR; Goff, DC; Jones, CL; Randall, OS; Sweeney, ME, 2001) |
| "The drugs used to treat hypertension may cause ED." | ( Khan, MA; Mikhailidis, DP; Milionis, HJ; Morgan, RJ, 2000) |
| "Several trials have shown that treatment of hypertension in the elderly, including the 'old elderly', is highly beneficial in terms of reduced morbidity and mortality." | ( Zannad, F, 2000) |
| "In the treatment of hypertension, especially with hyperuricemia, it might be important to select the drug, which does not influence or reduce the concentration of uric acid." | ( Saito, Y; Tatsuno, I, 2001) |
| "We have compared 25 patients with nontreated essential hypertension (11 women, 14 men) with 14 healthy volunteers (7 women, 7 men) matched for age." | ( Buczkowski, K; Klucz, K; Kretowicz, M; Manitius, J; Odrowaz-Sypniewska, G; Strózecki, P; Ukleja-Adamowicz, M, 2000) |
| "Lack of efficacy in the treatment of hypertension with only one drug presents a problem in general practice and often requires switching to another type of drug, because higher dosage of currently used antihypertensives increases the frequency of side effects." | ( Baumgart, P; Düsing, R; Pohlmeyer, H; Reismann, J, 2001) |
| "The aggressive treatment of hypertension in patients with impaired renal autoregulation may be associated with an increase in the serum creatinine concentration." | ( Palmer, BF, 2001) |
| "Despite their efficacy in treating hypertension, diuretics, beta-blockers, and calcium channel blockers have all been associated with numerous side effects, including increased serum lipid levels, insulin resistance, and edema." | ( Gavras, HP, 2001) |
| "The usefulness of carvedilol in the treatment of hypertension, ischemic heart disease, and congestive heart failure is based on a combination of hemodynamic benefits and cardiovascular protection." | ( Cheng, J; Kamiya, K; Kodama, I, 2001) |
| "Diabetes and treatment for hypertension were present in 3 and 22% among Turner syndrome women vs." | ( Bryman, I; Landin-Wilhelmsen, K; Wilhelmsen, L, 2001) |
| "The fixed combination V + H used for treatment of hypertension, after failure of monotherapy, is very effective in reducing pulse pressure, systolic and diastolic blood pressure, over 24 hours, homogeneously, and is as well tolerated as placebo." | ( Asmar, R; Ghobrial, H; Herpin, D; Mallion, JM; Poncelet, P; Vaïsse, B; Vaur, L, 2001) |
| "For the treatment of hypertension, this idea has the potential for a therapeutic paradigm shift." | ( Prisant, LM, 2001) |
| "This may represent an advantage in the treatment of hypertension with risk of brain damage." | ( Amenta, F; Sabbatini, M; Tomassoni, D, 2001) |
| "The primary aim in the medical treatment of hypertension is to lower blood pressure (BP)." | ( McVeigh, GE, 2001) |
| "The cost of treating hypertension represents a substantial percentage of total pharmacy expenditures at medical centers and by managed care organizations in the United States." | ( Yanchick, JK, 2001) |
| "Sixty-eight percent of patients treated for hypertension demonstrated clinical benefit (improved or cured hypertension)." | ( Caps, MT; Davies, MG; Glickerman, DJ; Harley, JD; Hatsukami, T; Kohler, TR; Yutan, E, 2001) |
| "To explore how well physicians who treat hypertension know the indications and contraindications for particular antihypertensive therapies, and how closely their opinions and practice of hypertension treatment agree with national guidelines." | ( Alpert, JS; Hartz, SC; Huse, DM; Roht, LH, 2001) |
| "The cost of treatment of hypertension was substantial and imparted a significant economic burden on the patients." | ( Jain, S; Karan, RS; Malhotra, S; Pandhi, P, 2001) |
| "The prevalence of treated hypertension in patients from the four groups was 16%, 12%, 2%, 10%, respectively." | ( Bull, SB; Honey, JD; Logan, AG; Pierratos, A; Rosivall, L; Tisler, A, 2002) |
| "Combined ET(B) blockade/DOCA-salt treatment worsened hypertension, increased left ventricular hypertrophy and induced right ventricular hypertrophy." | ( Bianciotti, LG; de Bold, AJ, 2002) |
| "In summary, the present information on treating hypertension in the diabetic overwhelmingly indicates a compelling need to lower BP to target diastolic BP of 80 mmHg or less, to be less concerned about the types of drugs used than the blood pressures achieved and the concordance with therapy and to rely on two or more antihypertensive drugs in the majority of cases." | ( Carruthers, SG, 2001) |
| "In 92 patients with chronically treated essential hypertension, two-dimensional and Doppler echocardiographic examinations were performed and LV inflow velocities were measured for evaluation of LV diastolic function." | ( Horio, T; Iwashima, Y; Kawano, Y; Kuroda, S; Takishita, S, 2002) |
| "Forty patients with untreated essential hypertension were given benidipine at a dose of 6 mg a day." | ( Fatema, K; Hirono, O; Kaneko, K; Kubota, I; Nitobe, J; Shiga, R; Takeishi, Y, 2002) |
| "Men and women (n = 88) being treated for hypertension with a mean baseline BP below 160/100." | ( Cherney, LM; Frazel, C; Geleva, D; Keenan, JM; O'Connor, PJ; Pins, JJ, 2002) |
| "Raloxifene treatment improves hypertension-induced endothelial dysfunction by increased bioavailability of NO." | ( Ahlbory, K; Böhm, M; Laufs, U; Linz, W; Nickenig, G; Rösen, R; Stamenkovic, D; Stasch, JP; Wassmann, S, 2002) |
| "Despite progress in the detection and treatment of hypertension the percentage of patients with controlled hypertension has failed to increase." | ( Abellan, J; Cucalón, JM; Fernández-Vega, F; Gómez de la Cámara, A; Maceira, B; Sanz de Castro, S, 2001) |
| "They should be considered for the treatment of hypertension in patients with heart failure, previous myocardial infarction, diabetes, or proteinuria." | ( Cheung, BM, 2002) |
| "Patients with treated hypertension should be monitored regularly when conventional NSAIDs or COX-2 inhibitors are administered." | ( Dijkmans, BA; Nurmohamed, MT; van Halm, VP, 2002) |
| "However, treating hypertension in the acute phase may cause further neurological deterioration." | ( Bacellar, AS; Jesus, PA; Oliveira-Filho, J; Pedreira, BB; Souza, PE, 2002) |
| "In patients with untreated hypertension, there is evidence of increased collagen synthesis, degradation, and inhibition of degradation resulting in fibrosis." | ( Dunn, FG; Lindsay, MM; Maxwell, P, 2002) |
| "Despite widespread use to treat childhood hypertension, enalapril has never been studied systematically to determine effectiveness, dose response, and safety in a pediatric population." | ( Frame, V; Herrera, P; Shahinfar, S; Shaw, W; Soffer, B; Wells, T; Zhang, Z, 2002) |
| "In addition to its effectiveness in the treatment of hypertension, CHF, and AMI, imidapril has beneficial effects in the treatment of diabetic nephropathy and asymptomatic dysphagia." | ( Hosoya, K; Ishimitsu, T, 2002) |
| "Clonidine is a medication long used to treat hypertension, and it is still used in the treatment of refractory hypertension." | ( Backo, AL; Clause, SL; Gibbs, KA; Triller, DM, 2002) |
| "With the use of ACE-inhibitors in the treatment of hypertension and heart failure, less attention has been paid to aldosterone." | ( Duprez, D, 2002) |
| "The drug may be approved for treatment of hypertension in 2002." | ( Carter, BL; Zillich, AJ, 2002) |
| "Medicinal herbs are used to treat burns, hypertension, and cancer and, although the herbs are readily available and inexpensive, they work slowly." | ( Wen, W, 1979) |
| "Factors that must be considered for the treatment of hypertension in patients, particularly with type 2 diabetes." | ( Dubourg, O; Forette, F; Hanon, O; Mallion, JM; Marre, M, 2002) |
| "Therapeutic agents for the treatment of hypertension may differ in their efficacy during the early-morning period, a time when both morbid and mortal cardiovascular events are increased compared with other times of the day." | ( Anders, RJ; Calhoun, D; Mansoor, GA; Sica, DA; White, WB, 2002) |
| "Guidelines for the treatment of hypertension underline the central importance of strenuous efforts to reduce the prevalence of smoking, as epidemiological studies consistently have demonstrated that smoking increases the risk of cardiovascular disease and death by some two- or three-fold." | ( Agewall, S; Fagerberg, B; Lindstedt, G; Persson, B, 2002) |
| "Aim of the study was treatment of hypertension in patients with DM of both types by the ACE inhibitor trandolapril in dose of 2-4 mg, possibly in combination with the calcium channel blocker verapamil--240 mg." | ( Cech, F; Rosolová, H; Sefrna, F, 2002) |
| "For now, the goals and methods of treating hypertension and dyslipidemia are the same in people with the metabolic syndrome as in the general population." | ( Hoogwerf, BJ; Nambi, V; Sprecher, DL, 2002) |
| "It may be useful for treating hypertension and angina pectoris, and may also have a cardiac protective function." | ( Harada, K; Ito, S; Nakaya, Y; Nishikado, A; Nomura, M; Uehara, K, 2003) |
| "Successful treatment of hypertension consisted of beta-adrenergic blockers, angiotensin converting enzyme inhibitors, and Ca channel blockers as monotherapy or in combination." | ( Alon, US; Geffner, ME; Lilien, M; Monzavi, R; Rasoulpour, M; Yadin, O, 2003) |
| "Pharmacologic treatment countered hypertension-dependent left ventricle and coronary artery changes in SHRs." | ( Amenta, F; Sabbatini, M; Tomassoni, D, 2003) |
| "Awareness and treatment of hypertension was slightly higher among the diabetic hypertensive subjects." | ( Deepa, R; Mohan, V; Pradeepa, R; Shanthirani, CS, 2003) |
| "A higher proportion of patients treated for hypertension for at least three months was found in the Slovak group (99." | ( Balazovjech, I; Jezek, T, 2003) |
| "Omapatrilat was targeted to treat patients with hypertension and congestive heart failure." | ( Burnier, M; Maillard, M; Zanchi, A, 2003) |
| "When deciding on treatment in human hypertension these results have important clinical implications." | ( Morgan, T, 2003) |
| "Fifteen patients with untreated arterial hypertension were enrolled." | ( Hussein, O; Radan, A; Reuven, V, 2003) |
| "Three treatments for hypertension patients with type 2 diabetes mellitus and nephropathy were assessed: (1) irbesartan, (2) amlodipine, and (3) placebo." | ( Annemans, L; Borenstein, J; Chen, RS; Chiou, CF; Lewis, EJ; Palmer, AJ; Rodby, RA; Roze, S; Sengupta, N; Simon, TA; Smitten, A, 2003) |
| "Twenty-one patients have been treated for hypertension with oral doses of hexamethonium salts, Apresoline(R) or combinations of both." | ( STUPPY, LJ, 1954) |
| "One month of drug treatment of hypertension significantly reduced systolic and diastolic blood pressure by 21." | ( Hesse, IF, 2003) |
| "In adults with treated hypertension, hypokalemia in the year before a stroke was associated with an increased risk of incident ischemic and hemorrhagic stroke independent of diuretic use when compared to normal serum K(+) levels." | ( Heckbert, SR; Kaplan, RC; Lemaitre, RN; Longstreth, WT; Psaty, BM; Smith, NL; Tirschwell, DL, 2003) |
| "LHC is safe in treating hypertension grade I and II with no adverse reaction." | ( Cui, L; Yu, XD; Zhou, WQ, 2003) |
| "Therefore, treatment for hypertension must be compatible with the symptoms of PAD." | ( Lip, GY; Makin, AJ, 2003) |
| "One of the current challenges in the treatment of hypertension is the variation in the incidence and morbidity among ethnic populations." | ( Ferdinand, KC, 2003) |
| "New guidelines for the treatment of hypertension were recently released both in Europe and the United States (see article by J." | ( Kulbertus, H, 2003) |
| "The risks and benefits of treating hypertension in individuals older than 80 years are uncertain." | ( Beckett, NS; Bulpitt, CJ; Cooke, J; Dumitrascu, DL; Gil-Extremera, B; Nachev, C; Nunes, M; Peters, R; Staessen, JA; Thijs, L, 2003) |
| "This study describes the treatment of hypertension and assesses the association between mortality and class of antihypertensive medication among a cohort of dialysis patients." | ( Allen, AS; Chua, BS; Griffith, TF; Klassen, PS; Reddan, DN; Szczech, LA, 2003) |
| "In vehicle-treated rats, hypertension was accompanied by tachycardia and marked increments in angiotensinogen and AT1A mRNA expression in the cardiovascular system-controlling brainstem areas." | ( Crescenzi, A; Michelini, LC; Sangaleti, CT, 2004) |
| "The authors conclude that treatment of hypertension with doxazosin in adults with glucose disorders incurs the same risk of coronary heart disease as treatment with chlorthalidone; however, treatment with doxazosin increases the risk of combined cardiovascular disease and heart failure despite lower glucose levels." | ( Barzilay, JI; Basile, JN; Bettencourt, J; Black, H; Ciocon, JO; Davis, BR; Ellsworth, A; Force, RW; Goff, DC; Habib, G; Margolis, KL; Wiegmann, T, 2004) |
| "Amlodipine is an effective treatment for hypertension." | ( Alexander, GJ; Brown, MJ; Byrne, CD; Neal, DA; Wilkinson, IB, 2004) |
| "The optimal first-line treatment of hypertension has been a contentious issue." | ( Fuchs, FD, 2003) |
| "In the treatment of hypertension in subjects of African origins, although hydrochlorothiazide (HCTZ) is not as effective as calcium channel blockers, indapamide is superior to HCTZ." | ( Candy, GP; Essop, MR; Hlatshwayo, NM; Kachope, J; Libhaber, CD; Libhaber, EN; Norton, GR; Puane, MO; Sareli, P; Sliwa, K; Woodiwiss, AJ, 2004) |
| "In untreated TGRs severe hypertension was associated with inward eutrophic remodelling of small arteries." | ( Agabiti-Rosei, E; Bianchi, R; De Ciuceis, C; Nussdorfer, GG; Paiardi, S; Porteri, E; Rezzani, R; Rizzoni, D; Rodella, L; Rossi, GP; Sleiman, I; Sticchi, D, 2004) |
| "The new guidelines for treatment of hypertension by the JNC VII in 2003 permit the initial use of a combination therapy, if blood pressure has to be lowered more than 20/10 mmHg." | ( Bönner, G; Fuchs, W, 2004) |
| "Patients with untreated hypertension (n=30, mean age 46." | ( Anisimova, LP; Ivanenko, VV; Legkiĭ, AV; Lopatin, IuM; Riazantseva, NV; Semenova, NV, 2004) |
| "Overall, 22 patients (27%) received treatment for hypertension following clozapine initiation." | ( Daley, TB; Hayden, D; Henderson, DC; Koul, P; Kunkel, L; Rodrigues-Scott, M, 2004) |
| "In conclusion, treatment of hypertension with irbesartan resulted in a significant reduction in the voltage criteria for LVH, although an effect on LVM was only seen in subjects with high baseline LVM." | ( Delles, C; Klingbeil, AU; Kolloch, RE; Krekler, M; Ludwig, M; Schmieder, RE; Schneider, MP; Stumpe, KO, 2004) |
| "Early treatment of hypertension minimizes damage to vital organs." | ( Thompson, J, 2004) |
| "LHC has quite a promising effect in treating essential hypertension of Phlegm-stasis blocking Collateral type, the mechanism might be related with the improvement of hemorrheological parameters, increasing blood NO level and decreasing ET and Ang II levels." | ( Kim, R; Zhou, WQ, 2004) |
| "Chronic rosiglitazone treatment retards hypertension development, but the associated prohypertrophy effect calls for a cautious use of this thiazolidinedindione in the treatment of insulin resistance syndrome associated with hypertension." | ( De Champlain, J; Wang, R; Wilson, TW; Wu, L, 2004) |
| "Therapeutic agents for the treatment of hypertension may differ in their efficacy during the early morning period, a time when both morbid and mortal cardiovascular events are increased compared to other times of the day." | ( Albert, KS; Gana, T; Lacourciere, Y; Pascual, MG; Smith, DH; White, WB, 2004) |
| "It has been approved for the treatment of hypertension, and may be used alone or in combination with other antihypertensive agents." | ( Devereux, RB; Lyle, PA, 2004) |
| "All patients started on ACE or ARB for treatment of hypertension within 90 days of their transplant were included in the analysis (n = 17)." | ( Bia, MJ; Formica, RN; Friedman, AL; Lorber, MI, 2004) |
| "Its indication is the treatment of hypertension." | ( Krzesinski, JM; Scheen, AJ, 2004) |
| "Our data indicate that (a) the ANT treatment prevented hypertension, cardiac hypertrophy, and production of ROS, (b) the PRO treatment prevented insulin resistance, hypertriglyceridemia, and overproduction of ROS but had only minor effects on hypertension or hypertrophy, while (c) Vitaflavan prevented hypertension, cardiac hypertrophy, and overproduction of ROS." | ( Al-Awwadi, NA; Araiz, C; Azay, J; Bornet, A; Cristol, JP; Cros, G; Delbosc, S; Linck, N; Teissedre, PL, 2005) |
| "Preliminary data suggest that treatment of hypertension with eplerenone may provide protective effects against end-organ disease; further work is needed to elucidate the clinical significance of these findings, and to evaluate the outcome of treatment of hypertension in terms of cardiovascular morbidity and mortality and quality of life." | ( Croom, KF; Perry, CM, 2005) |
| "Candesartan cilexetil is a possible treatment for hypertension in renal allograft recipients." | ( Birkel, M; Kiel, G; Philipp, T; Pietruck, F; Stahlheber-Dilg, B, 2005) |
| "Both drugs are used to treat hypertension, but only verapamil can be used to produce atrioventricular block in patients with atrial fibrillation." | ( Barrett, TD; Maurice, DH; Triggle, DJ; Walker, MJ, 2005) |
| "We reviewed non-pharmacological treatment of hypertension in the elderly." | ( Ohta, T; Suzuki, S, 2005) |
| "Losartan is a safe, effective long-term treatment for hypertension or posttransplant erythrocytosis (PTE) in renal transplant recipients." | ( Cift, A; Dilek, K; Ersoy, A; Ersoy, C; Kahvecioglu, S, 2005) |
| "In conclusion the diagnosis and treatment of hypertension in the population of Kosovo during the post war period had certain particularities." | ( Hatzitolios, AI; Koutsopoulos, D; Markoglou, NCh; Metallidis, S; Savopoulos, ChG; Ziakas, AG, 2005) |
| "CT-1 levels in matched patients with treated hypertension (THT, 618+/-10 pmol/L, n=35) were similar to those in UTH patients, but higher than in NT controls (P<0." | ( Cameron, VA; Pemberton, CJ; Raudsepp, SD; Richards, AM; Yandle, TG, 2005) |
| "We have shown that treatment of hypertension with ACE inhibitors (ACE-I) enhances relaxation to acetylcholine in human internal thoracic artery (ITA) above this in nonhypertensive patients receiving no ACE-I." | ( Biernat, J; Deja, MA; Gołba, KS; Kolowca, M; Malinowski, M; Mrozek, R; Widenka, K; Woś, S, 2005) |
| "Although the treatment of hypertension in diabetics reduces cardiovascular and microvascular complications, the ideal strategy for treating hypertension in diabetics has not been well defined and warrants a combination approach." | ( Kumar, AH; Ramarao, P, 2005) |
| "ARBs are first-line agents for the treatment of hypertension and cardiovascular diseases." | ( de la Sierra, A; Sierra, C, 2005) |
| "It is indicated for the treatment of hypertension in patients who require more than one agent to achieve blood pressure (BP) targets." | ( Keam, SJ; Reynolds, NA; Wagstaff, AJ, 2005) |
| "These drugs are commonly used for the treatment of hypertension and cardiac failure." | ( Kauffmann, R; Orozco, R; Venegas, JC, 2005) |
| "Therefore, future treatments for hypertension may require a combination of drugs performing complimentary tasks in lowering arterial pressure and reversing maladaptive physiologic and genetic processes causing hypertensive heart disease." | ( Diamond, JA; Phillips, RA, 2005) |
| "New therapeutic strategies for treatment of hypertension are suggested by this hypothesis." | ( Phillips, WT, 2006) |
| "Guidelines for the treatment of hypertension recommend reducing blood pressure to below 140/90 mmHg." | ( Waeber, B, 2005) |
| "The indication for treatment was hypertension in about 90% of cases." | ( Delabar, U; Eichelbaum, M; Fux, R; Gleiter, CH; Kivistö, KT; Lorenz, G; Mörike, K; Pröhmer, AM; Schaeffeler, E; Schwab, M, 2005) |
| "We examined the prevalence and medical treatment of hypertension among 15,904 ACS patients randomized in the SYMPHONY and 2nd SYMPHONY trials." | ( Armstrong, PW; Aylward, PE; Bhapkar, MV; Frazier, CG; Klein, WW; Kristinsson, A; McGuire, DK; Newby, LK; Sadowski, Z; Shah, SH; Weaver, WD, 2005) |
| "Without treatment, the hypertension prevalence as well as mean systolic BP decline over time demonstrating the statistical phenomenon of regression to the mean." | ( Agarwal, M; Gupta, R; Gupta, VP; Tongia, R, 2005) |
| "Despite efforts to diagnose and treat hypertension effectively, the goal of lowering blood pressure (BP) levels is rarely achieved, as treatment is often initiated with a single antihypertensive agent." | ( Bida, M; Dörffel, Y; Hansen, A; Juncken, D; Rangoonwala, B; Ritz, A; Schnitker, J; Scholze, J, 2006) |
| "We investigated whether pharmacologic treatment of prehypertension prevents or postpones stage 1 hypertension." | ( Black, HR; Egan, BM; Grimm, RH; Julius, S; Kaciroti, N; Messerli, FH; Michelson, EL; Nesbitt, SD; Oparil, S; Schork, MA; Weber, MA, 2006) |
| "Thus, treatment of prehypertension appears to be feasible." | ( Black, HR; Egan, BM; Grimm, RH; Julius, S; Kaciroti, N; Messerli, FH; Michelson, EL; Nesbitt, SD; Oparil, S; Schork, MA; Weber, MA, 2006) |
| "This has important implications for the treatment of hypertension, congestive heart failure, renal insufficiency and metabolic syndrome." | ( Dell'Oro, R; Grassi, G; Mancia, G; Quarti-Trevano, F; Scopelliti, F, 2006) |
| "Six patients with SDB and treated arterial hypertension, six normotensive patients with SDB, and six healthy controls received sleep studies and an assessment of venodilation using the dorsal hand vein technique." | ( Duchna, HW; Guilleminault, C; Orth, M; Schultze-Werninghaus, G; Stoohs, RA, 2006) |
| "L-NAME treatment leads to hypertension, proteinuria and renal fibrosis." | ( Feng, Y; Lang, F; Liu, Z; Wang, Y; Xiong, J; Yard, B, 2006) |
| "This was also the case in STRAtegies of Treatment in Hypertension: Evaluation, a postregistration study versus current monotherapies and stepped-care therapy with different classes of antihypertensive agents." | ( Gosse, P, 2006) |
| "Chronic ouabain treatment produces hypertension acting on the central nervous system and at vascular levels." | ( Amanso, AM; Carvalho, CR; Falcochio, D; Moreira, CM; Rossoni, LV; Tanoue, CU; Vassallo, DV; Xavier, FE, 2006) |
| "Pharmacological treatment of hypertension represents a cost-effective way of preventing cardiovascular and renal complications." | ( Waeber, B, 2006) |
| "It is predicted that future treatment of hypertension will be increasingly tailored to the epidemiologic profiles and medical costs of individual communities." | ( Ikeda, S; Ikegami, N; Sakamaki, Y; Saruta, T; Sasamura, H, 2006) |
| "Fosinopril was effective in treating hypertension, but black children required a higher dose per body weight in order to achieve adequate control." | ( Benjamin, DK; Berezny, KY; Califf, RM; Deitchman, D; Hazan, L; Hogg, R; Kay, JD; Kilaru, R; Li, JS; Menon, S; Portman, R, 2006) |
| "5,369 individuals (> or =20 years) with treated hypertension delivered three morning urine samples for microalbuminuria analysis." | ( Hallan, H; Holmen, J; Krüger, O; Kvenild, K; Midthjell, K; Romundstad, S, 2006) |
| "Patients with treated hypertension, lipid-lowering therapy, renal insufficiency or structural heart disease other than left ventricular hypertrophy were excluded." | ( Conen, D; Dieterle, T; Martina, B; Rimner, M; Utech, K, 2006) |
| "Subjects with treated hypertension (N = 299) were excluded from analyses of SBP and DBP but included in analyses of hypertension prevalence." | ( Bremner, AP; Bulsara, MK; Feddema, P; Leedman, PJ; Michelangeli, V; O'Leary, P; Walsh, JP, 2006) |
| "However, when formally indicated to treat hypertension in a specific patient, they should not be switched to another antihypertensive agent." | ( Baptista, A; Carrasqueira, H; Faísca, M; Iglesias, A; Morgado, E; Neves, PL; Silva, AP; Soares, C, 2007) |
| "Forty-three patients with untreated essential hypertension were randomized to receive amlodipine (n=22) or telmisartan (n=21), which were respectively administered at doses of 5 mg and 40 mg once daily in the morning for 24 weeks." | ( Maki, K; Morimoto, S; Sawada, K; Yano, Y, 2006) |
| "Beta-blockers have been widely used to treat hypertension and are still recommended as first-line drugs in guidelines." | ( Athyros, VG; Kakafika, AI; Karagiannis, A; Mikhailidis, DP; Tziomalos, K, 2007) |
| "Lercanidipine may be an option in the treatment of hypertension, as current literature suggests comparable antihypertensive efficacy and better tolerability." | ( Beckey, C; Lundy, A; Lutfi, N, 2007) |
| "There are profound benefits of treating hypertension: antihypertensive therapy has been associated with large reductions in stroke, myocardial infarction and heart failure." | ( Preston, RA, 2007) |
| "One third of patients treated for hypertension attain adequate blood pressure (BP) control, and multidrug regimens are often required." | ( Alvarado, R; Glazer, R; Graff, A; Huang, J; Pool, JL; Weinberger, M, 2007) |
| "The efficacy and safety of aliskiren in treating hypertension has been studied in clinical trials both as monotherapy, comparing it with existing antihypertensive therapies, and in combination with other antihypertensive agents, including the diuretic hydrochlorothiazide, the angiotensin-converting enzyme inhibitor ramipril, and the calcium channel blocker amlodipine." | ( Gradman, AH; Traub, D, 2007) |
| "Current guidelines for the treatment of hypertension do not provide specific recommendations for obese hypertensive patients." | ( Grimm, E; Herrmann, D; Kintscher, U; Scholze, J; Unger, T, 2007) |
| "Hence treating hypertension with specific aldosterone antagonists may be a better approach in this group of patients." | ( Alhashmi, K; Connell, JM; Ford, I; MacDonald, TM; McInnes, GT; McMahon, AD; Parthasarathy, HK; Struthers, AD, 2007) |
| "As combination therapy for the treatment of hypertension, Ca channel blockers (CCBs), angiotensin II (AII) receptor blockers (ARBs), and/or AII-converting enzyme (ACE) inhibitors are mainly prescribed, while the efficacy of alpha(1)-blockers in such combination therapy remains unknown." | ( Eto, K; Ohta, Y; Onaka, U; Tsuchihashi, T; Ueno, M, 2007) |
| "Pharmacological treatment of hypertension represents a cost-effective way for preventing cardiovascular and renal complications." | ( Ambrosioni, E; Holzgreve, H; Laurent, S; Mancia, G; Ruilope, LM; Struijker-Boudier, HA; Waeber, B, 2007) |
| "Twenty-six patients with untreated essential hypertension were prospectively assigned to treatment with either olmesartan (27." | ( Fujii, S; Furumoto, T; Katoh, C; Morita, K; Naya, M; Tamaki, N; Tsukamoto, T; Tsutsui, H, 2007) |
| "The majority of infants do not require treatment for hypertension by 6 months of age." | ( Falk, MC; Kent, AL; Seliem, WA; Shadbolt, B, 2007) |
| "Fifty patients with untreated essential hypertension were randomized to receive 5 mg of amlodipine (n = 25) or 10 mg of cilnidipine (n = 25) once daily in the morning for 24 weeks." | ( Iwasaka, T; Maki, K; Morimoto, S; Yano, Y, 2007) |
| "Finally, current medications used in treating hypertension in ACS will be compared with regards to their mode of action and prognostic value." | ( Kühl, M; Lip, GY; Varma, C, 2007) |
| "Beta blockers used for the treatment of hypertension may be associated with increased risk for new-onset diabetes mellitus (DM)." | ( Bangalore, S; Grossman, E; Messerli, FH; Parkar, S, 2007) |
| "However, timely detection and treatment of hypertension seems to contribute to the preservation of cognition." | ( Birkenhäger, WH; de Leeuw, PW; Richart, T; Staessen, JA, 2007) |
| "Oral hydralazine treatment to reduce hypertension reduced SHR UCCR7." | ( Chalifour, LE; Huynh, H; Servant, N, 2007) |
| "Nondiabetic patients with treated or untreated hypertension were evaluated if they did not take diuretics and their office systolic BP (SBP) >140 mm Hg or diastolic BP (DBP) >90 mm Hg." | ( Chen, JW; Huang, CC; Leu, HB; Lin, SJ; Wu, TC, 2008) |
| "Concerning drug treatment of hypertension associated with other cardiometabolic risk factors, many results of head-to-head studies have demonstrated a reduction in new-onset Type 2 diabetes in hypertensive patients treated with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers, when compared with conventional antihypertensive therapy." | ( Celoria, BM; Francischetti, A; Francischetti, EA; Genelhu, VA, 2008) |
| "In 2007, it was approved for the treatment of hypertension by the US Food and Drug Administration and the European Medicines Agency." | ( Brunner, HR; Herold, P; Jensen, C, 2008) |
| "Our results demonstrate that treatment of hypertension with eprosartan normalizes blood pressure and corrects oxidative disturbances, suggesting that leucocytes could be a target for this drug." | ( Beltrán, B; Gabriel, F; Guiral, V; Labiós, M; Martínez, M; Muñoz, A; Ruiz-Aja, S, 2008) |
| "Pharmacological treatment of hypertension is effective in preventing cardiovascular and renal complications." | ( Feihl, F; Gojanovic, B; Liaudet, L; Waeber, B, 2008) |
| "Both agents effectively treat hypertension and heart failure but comparisons are complicated by the deficiency of head-to-head trials and differences between patient populations." | ( Krum, H; Struthers, A; Williams, GH, 2008) |
| "Thus, the treatment of hypertension and hyperlipidemia associated with hyperuricemia is also important." | ( Hisatome, I; Igawa, O; Ogino, K, 2008) |
| "Potentiation of NO could be used in the treatment of supine hypertension, and its inhibition offers a novel approach to improve orthostatic hypotension." | ( Biaggioni, I; Christman, B; Diedrich, A; Farley, G; Gamboa, A; Paranjape, SY; Raj, SR; Robertson, D; Shibao, C, 2008) |
| "We randomized 40 subjects with untreated hypertension (mean +/- s." | ( Feely, J; Mahmud, A, 2008) |
| "At doses used to treat hypertension, there is no evidence of inflammatory parameters being modified by ARBs in patients with more advanced kidney disease due to T2D." | ( Böger, RH; Galle, J; Pinnetti, S; Schwedhelm, E; Wanner, C, 2008) |
| "We investigated the effect of treatment of hypertension on cognition with the angiotensin-receptor-blocker, candesartan, in a placebo-controlled, double-blind, randomized controlled trial at one center participating in the Study on Cognition and Prognosis in the Elderly." | ( Ford, GA; Harrington, F; McKeith, IG; Saxby, BK; Wesnes, KA, 2008) |
| "Here, we test whether pharmacological treatment of hypertension normalizes regional cerebral blood flow responses and whether it does so differentially according to drug class." | ( Christie, IC; Jennings, JR; Meltzer, CC; Muldoon, MF; Price, J, 2008) |
| "The role of doxazosin in treatment of hypertension remains controversial." | ( Chang, CL; Chapman, N; Dahlöf, B; Poulter, NR; Sever, PS; Wedel, H, 2008) |
| "We think that to gain success in the treatment of hypertension educating the society is important and there should be clinical studies about the effect of lemon juice on blood pressure, which is one of the most common alternative therapies in our country." | ( Adibelli, Z; Akpolat, T; Dilek, M, 2009) |
| "Despite advances in the prevention and treatment of hypertension over the past decade, hypertension remains an important public health challenge." | ( Harper, KJ; Houston, MC, 2008) |
| "Aliskiren is approved for the treatment of hypertension at once-daily doses of 150 mg and 300 mg." | ( Dieterich, HA; Dole, WP; Howard, D; Jarugula, V; Vaidyanathan, S, 2008) |
| "Beta-blockers have been used to treat hypertension for decades, either as monotherapy or combined with other antihypertensive agents, primarily diuretics, often as fixed-dose combination products." | ( Black, HR; Sica, DA, 2008) |
| "Adequate monitoring and treatment of hypertension is recommended." | ( Stergiopoulos, K; Wu, S; Zhu, X, 2009) |
| "Current treatments for hypertension and its co-morbidities that work by manipulating this system will be discussed." | ( Huang, J; Lieb, DC; Siragy, H, 2008) |
| "Calcium antagonists are used in the treatment of hypertension and angina." | ( Coca, A; Sierra, C, 2008) |
| "CLV is a safe and effective treatment for acute hypertension in patients undergoing cardiac surgery." | ( Aronson, S; Cheung, AT; Dyke, CM; Kereiakes, DJ; Levy, JH; Lumb, PD; Newman, MF; Stierer, KA, 2008) |
| "The concomitant use of medication to treat hypertension or dyslipidaemia was not associated with an increase in adverse events following vardenafil treatment." | ( Eardley, I; Guay, AT; Lee, JC, 2008) |
| "Patients had either untreated hypertension or treated hypertension." | ( Beevers, G; Caulfield, M; Collins, R; Dahlöf, B; Kjeldsen, SE; Kristinsson, A; McInnes, GT; Mehlsen, J; Nieminen, M; O'Brien, E; Ostergren, J; Poulter, NR; Sever, PS; Wedel, H, 2008) |
| "Therefore, the use of l-arginine in the treatment of hypertension warrants investigation." | ( Mattson, DL; Rajapakse, NW, 2009) |
| "Of 2221 patients with untreated hypertension who received OM (mainly 10 or 20 mg), 331 patients whose blood pressure (BP) was measured at 1 week after initiation of treatment were defined as the "early BP determination group,'' whereas the remaining 1890 patients were defined as the ;;standard BP determination group." | ( Hiramatsu, K; Ishikawa, M; Komiya, M; Kushiro, T; Matsushita, Y; Sagawa, K; Saito, I, 2008) |
| "Adding amlodipine to valsartan for treatment of hypertension results in clinically meaningful reductions in blood pressure, on an overall basis and in high-risk subgroups who may benefit the most from blood pressure control." | ( Edelsberg, J; Kartashov, A; Keskinaslan, A; Levy, DG; Oster, G; Weycker, D, 2008) |
| "Patients receiving treatment for hypertension or dyslipidemia were also included in the study and these were considered in the diagnosis of MetS even if the parameters were normal." | ( Gala, K; Gill, N; Hoskote, SS; Joshi, SR; Panikar, V; Shah, DB; Surana, SP; Susheja, S, 2008) |
| "CYT-006-AngQb was designed to treat hypertension with the benefit of relatively long-lasting effects that do not require daily dosing." | ( Phisitkul, S, 2009) |
| "Pharmacological treatment of hypertension is effective in preventing cardiovascular and renal complications." | ( Ruilope, LM; Waeber, B, 2009) |
| "However, the significance of treatment of hypertension with high-dose ARB remains to be defined." | ( Arakawa, K; Jinnouchi, T; Kim-Mitsuyama, S; Matsui, K; Ogawa, H, 2009) |
| "Thus, in treatment of hypertension with ARBs, a new possibility for personalized medicine has been shown." | ( Aoyama, C; Fuchs, S; Inoki, I; Kato, N; Konoshita, T; Makino, Y; Miyamori, I; Mizuno, S; Motomura, M; Pinet, F; Wakahara, S, 2009) |
| "This translates into an impact of never-treated hypertension on LVMI in centrally obese, but not in lean people in groups of African descent in South Africa." | ( Libhaber, C; Libhaber, E; Majane, OH; Makaula, S; Maseko, MJ; Norton, GR; Woodiwiss, AJ, 2009) |
| "It is indicated for the treatment of hypertension (including as initial therapy in severe hypertension) and for stroke risk reduction in patients with hypertension and left ventricular hypertrophy (LVH)." | ( Keating, GM, 2009) |
| "It was launched in 1998 for the treatment of hypertension." | ( Mendis, B; Page, SR, 2009) |
| "Aggressive BP monitoring and treatment of hypertension may achieve uninterrupted, full-dose therapy in most patients treated with sunitinib." | ( Bamias, A; Dimopoulos, MA; Gyftaki, R; Koroboki, E; Lainakis, G; Manios, E; Zakopoulos, N, 2009) |
| "A 29-year-old man had been treated for hypertension for 10 years." | ( Amano, T; Imao, T; Takemae, K; Yamauchi, K, 2009) |
| "In the last years, the treatment of hypertension in children and adolescents has been characterized by an improvement in the definition of hypertension and the more widespread use of the 24-h blood pressure monitor to define the hypertension pattern and assess efficacy of the therapy." | ( Araya, CE; Garin, EH, 2009) |
| "As a consequence prolonged antioxidant treatment in human hypertension may fail to provide the expected clinical profit." | ( Pechanova, O; Simko, F, 2009) |
| "A major adverse effect of these treatments is hypertension, suggesting a critical role for VEGF in blood pressure (BP) regulation." | ( Coffman, TM; Facemire, CS; Griffiths, R; Hurwitz, H; Nixon, AB, 2009) |
| "However, when considering the costs of treating hypertension in a population it is also necessary to assess the adverse effects that diuretics produce, particularly in elderly people." | ( Domínguez-Gil, A; Gregori, JA; Nuñez, JF, 2009) |
| "Current treatments for hypertension and heart failure have proven beneficial but are not highly specific and associated with side effects." | ( Anderson, HD; Behbahani, J; Juric, D; Kopilas, MA; Louis, XL; Netticadan, T; Thandapilly, SJ; Wojciechowski, P; Yu, L, 2010) |
| "To show that rapid successful treatment of hypertension leads to improvement in cardiac morphology and function regardless of the pharmacological agents used." | ( Day, AG; Ogunyankin, KO, 2009) |
| "Tempol treatment improved hypertension and renal injury, and reduced ET-1 concentrations and superoxide anion production." | ( Agharazii, M; Larivière, R; Lebel, M; Rancourt, ME; Rodrigue, ME, 2010) |
| "Chronic L-NAME treatment induced hypertension, elevated the oxidative load and inhibited NOS activity." | ( Barta, A; Celec, P; Gardlik, R; Kunes, J; Paulis, L; Pechanova, O; Simko, F; Zicha, J, 2010) |
| "Aliskiren is approved for the treatment of hypertension at once-daily doses of 150 or 300 mg by the US Food and Drug Administration and the European Commission." | ( Boye, S; Jin, J; Keefe, DL; Puig, JG; Schunkert, H; Taylor, AA, 2009) |
| "In patients with untreated essential hypertension, increased hs-CRP and ADMA levels are associated with microalbuminuria, suggesting the involvement of inflammation and endothelial dysfunction in vascular and kidney damage." | ( Andrikou, E; Dimitriadis, K; Mihas, C; Miliou, A; Papademetriou, V; Stefanadi, E; Stefanadis, C; Thomopoulos, C; Tsiachris, D; Tsioufis, C, 2010) |
"Eligible patients had treated or untreated hypertension, >or=3 additional cardiovascular risk factors, and baseline total cholesterol| ( Al Khadra, A; Erdine, S; Kim, JH; Lopez, AP; Sutradhar, S; Westergaard, M; Yunis, C; Zamorano, J, 2010) | |
| "The optimal combination treatment for hypertension has not been established." | ( Doi, M; Hirohata, S; Kaji, Y; Kamikawa, S; Kusachi, S; Miyoshi, T; Ninomiya, Y; Ogawa, H; Sakane, K; Usui, S, 2010) |
| "In 1112 never-treated essential hypertension patients and 203 normotensive controls, tightly linked SNPs of beta-adrenergic receptors (ADRB1 - Ser49Gly and Arg389Gly; ADRB2 - Cys19Arg, Gly16Arg and Gln27Glu) and the G-protein beta3-subunit (GNB3 - A3882C, G5249A and C825T) were genotyped." | ( Argiolas, G; Bulla, E; Bulla, P; Degortes, S; Filigheddu, F; Frau, F; Glorioso, N; Pitzoi, S; Troffa, C; Zaninello, R, 2010) |
| "We studied 130 men and 186 women with untreated mild hypertension, 44." | ( Ayala, DE; Hermida, RC, 2010) |
| "We investigated the effect of vitamin D treatment on hypertension in a three-arm randomized placebo controlled pilot and feasibility study." | ( Judd, SE; Kumari, M; Raiser, SN; Tangpricha, V, 2010) |
| "Participants treated for hypertension but who had BP > or = 140/90 mm Hg had the greatest amount of WML volumes." | ( Bryan, NR; Gaussoin, SA; Kerwin, D; Kuller, LH; Limacher, M; Margolis, KL; Robinson, JG; Wassertheil-Smoller, S; Williamson, J, 2010) |
| "Six subjects with treatment-resistant hypertension were included, and their usual antihypertensive medication was continued during the study." | ( Dear, JW; Hughes, VE; Oliver, JJ; Webb, DJ, 2010) |
| "A common recommendation for the treatment of hypertension is dietary salt intake restriction." | ( Jourdan, K; Tayie, FA, 2010) |
| "In young untreated TGR, severe hypertension rapidly evolved." | ( Cervenka, L; Husková, Z; Kramer, HJ; Kujal, P; Mrázová, I; Rakusan, D; Thumová, M; Vanecková, I; Vanourková, Z; Vernerová, Z, 2010) |
| "In conclusion, untreated hypertension was associated with a reduced risk of bladder cancer." | ( Castelao, JE; Coetzee, GA; Conti, DV; Cortessis, VK; Gago-Dominguez, M; Groshen, S; Jiang, X; Pike, MC; Stern, MC; Yuan, JM, 2010) |
| "Triple therapy is recommended in the treatment of hypertension in those patients not adequately controlled with two antihypertensive drugs." | ( Barrios, V; Escobar, C, 2010) |
| "CIVN, used to treat post-KTX hypertension, may inhibit TAC metabolism resulting in overexposure and potential toxicity." | ( Carle, AC; Goebel, J; Hooper, DK; Schuchter, J, 2011) |
| "Although ouabain treatment induced hypertension in all groups, a larger noradrenaline induced contraction was observed over 20 weeks of treatment." | ( Davel, AP; Rossoni, LV; Wenceslau, CF; Xavier, FE, 2011) |
| "NEP inhibitors were effective in the treatment of hypertension and heart failure but the relatively high incidence of angioedema stopped their widespread use." | ( Cuculi, F; Erne, P, 2011) |
| "Patients with treatment-resistant hypertension usually have OSA and have had a good antihypertensive response to spironolactone." | ( Milic, M; Sun, P; Ziegler, MG, 2011) |
| "Carvedilol is an effective treatment in hypertension and chronic heart failure." | ( Brockmöller, J; Gültepe, S; Meineke, I; Sehrt, D; Tzvetkov, M, 2011) |
| "It may be useful in treating severe hypertension with elevated heart rate in metabolic syndrome." | ( Satou, Y; Ueno, N, 2011) |
| "Efforts to increase the awareness and treatment of hypertension in the population at large may lower the incidence of hypertensive crisis and its complications." | ( Beutler, JJ; de Gooijer, A; Gaillard, CA; Kroon, AA; van den Born, BJ; van den Meiracker, AH, 2011) |
| "Twenty-five subjects with untreated mild hypertension received in random order 250 g of study product (25 mg peptides and 2 g plant sterols) or placebo." | ( Ehlers, PI; Filler, I; Jähnchen, E; Järvenpää, S; Kivimäki, AS; Korpela, R; Turpeinen, AM; Vapaatalo, H; Wagner, F; Wiegert, E, 2011) |
| "This review provides an update of ESA treatment, hypertension and LVH in the CKD patient, indicating that pathogenesis of LVH in this population is currently not completely understood." | ( Lederer, SR; Schiffl, H; Schmid, H, 2011) |
| "It has been used to treat hypertension and angina pectoris." | ( Cui, WD; Ding, BP; Huang, ZG; Zhang, NB, 2011) |
| "The patient was not given any treatment of hypertension, psychosis or seizures, except vitamin B(12) injections." | ( Akbayram, S; Ariyuca, S; Cesur, Y; Dogan, M; Dogan, ŞZ; Ozdemir, O; Peker, E, 2012) |
| "Traditional treatment of hypertension including angiotensin converting enzyme inhibitors, calcium antagonists, diuretics and beta-blockers was prescribed to controls." | ( Skotnikov, AS; Skotnikova, EV; Vertkin, AL; Vilkovyskiĭ, FA; Zviagintseva, EI, 2011) |
| "Polytherapy was the norm for treating hypertension." | ( Bhandari, SK; Kalantar-Zadeh, K; Laragh, JH; Rasgon, SA; Sealey, JE; Shi, J; Sim, JJ, 2012) |
| "Patients with untreated systemic hypertension and normal left ventricular systolic function in sinus rhythm (n = 20; six males/14 females; age 35 - 69 years, mean ± SD 52." | ( Asker, M; Asker, S; Karadag, MF; Timucin, OB, 2011) |
| "A 41-yr-old Japanese male was treated for hypertension and hypokalemia for 5 yr." | ( Demura, M; Karashima, S; Kometani, M; Takata, H; Takeda, Y; Yamagishi, M; Yoneda, T, 2012) |
| "Nifedipine as a pharmacologic agent for treating hypertension and angina pectoris has been available worldwide since the early 1980's." | ( Elliott, HL; Meredith, PA; Toal, CB, 2012) |
| "Patients with treatment resistant hypertension are at increased risk of developing cardiovascular end organ damage." | ( Harazny, JM; Michelson, G; Raff, U; Schmidt, BM; Schmieder, RE; Titze, SI, 2012) |
| "Eighty-eight patients with POAG and treated, controlled hypertension were examined." | ( Głuszek, J; Karolczak-Kulesza, M; Krasińska, B; Krasiński, Z; Lopatka, P; Pawlaczyk-Gabriel, K; Tykarski, A, 2012) |
| "The utility of β-blockers in the treatment of hypertension has created much speculation as to their efficacy in patients with comorbid conditions, and there are concerns regarding their adverse metabolic effects." | ( Fares, H; Lavie, CJ; Ventura, HO, 2012) |
| "470 subjects (aged 68 yrs) neither treated for hypertension nor diagnosed for SRBD were included." | ( Achour-Crawford, E; Barthélémy, JC; Celle, S; Chouchou, F; Lévy, P; Maudoux, D; Ntougou-Assoumou, HG; Pépin, JL; Pichot, V; Roche, F; Tamisier, R, 2012) |
| "The drug is indicated for the treatment of hypertension and renal impairment in patients with type 2 diabetes mellitus (T2D) and hypertension, and its tolerability and safety profile have been extensively investigated and reported to be similar to placebo." | ( Borghi, C; Cicero, AF, 2012) |
| "Addition of MR antagonists to standard treatment for hypertension and cardiac or renal disease decreases end-organ pathology and sympathetic nerve activation (SNA), and increases quality of life indices." | ( Gomez-Sanchez, CE; Gomez-Sanchez, CM; Gomez-Sanchez, EP; Hawkins, UA, 2012) |
| "Twenty patients with untreated essential hypertension (M/F = 13/7, aged 55." | ( Adachi, H; Hoshizaki, H; Kasama, S; Kawaguchi, R; Koyama, K; Murakami, J; Oshima, S; Sato, C; Toyama, T; Yamashita, E, 2012) |
| "Thirteen patients with treated hypertension and compensated HFPEF consumed the DASH/SRD for 21 days (all food/most beverages provided)." | ( Brook, RD; Hummel, SL; Kolias, TJ; Rosenblum, HR; Seymour, EM; Sheth, SS; Weder, AB; Wells, JM, 2012) |
| "In the treatment of hypertension, prior knowledge of the level of plasma PTX3 could be important in antihypertensive drug choice." | ( Arslan, E; Ay, SA; Balta, S; Bulucu, F; Cakar, M; Celik, T; Demirbas, S; Demirkol, S; Karaman, M; Sağlam, K; Turker, T; Unlu, M; Yaman, H, 2013) |
| "Initiating treatment of hypertension with beta-blockers leads to modest reductions in cardiovascular disease and no significant effects on mortality." | ( Bradley, HA; Mayosi, BM; Mbewu, A; Opie, LH; Volmink, J; Wiysonge, CS, 2012) |
| "Effective treatment of hypertension is a key strategy for preventing and reducing the burden of hypertension-related cardiovascular diseases." | ( Paneni, F; Passerini, J; Tocci, G; Volpe, M, 2012) |
| "In the treatment of hypertension, prior knowledge of the plasma cholesterol levels can be important in antihypertensive drug choice." | ( Akhan, M; Arslan, E; Arslan, Z; Ay, SA; Balta, S; Bulucu, F; Cakar, M; Celik, T; Demirbas, S; Demirkol, S; Karaman, M; Saglam, K; Sarlak, H, 2013) |
| "In 205 patients with untreated essential hypertension, we measured components of the renin-angiotensin-aldosterone system, plasma levels of fibrinogen, D-dimer, prothrombin fragment 1 + 2 (F1 + 2), and plasminogen activator inhibitor-1 (PAI-1), and assessed cardiac characteristics with standard echocardiography." | ( Catena, C; Colussi, G; Sechi, LA; Valeri, M, 2013) |
| "However, these associations in untreated hypertension remain unknown." | ( Androulakis, E; Chatzistamatiou, E; Kallikazaros, I; Miliou, A; Moustakas, G; Oikonomou, E; Papageorgiou, N; Stefanadis, C; Tousoulis, D, 2013) |
| "We conducted the Azelnidipine Treatment for Hypertension Open-label Monitoring in the Early morning (At-HOME) Study by surveying patients who were taking azelnidipine." | ( Hiramatsu, K; Kario, K; Komiya, M; Sato, Y; Shimada, K; Shiosakai, K; Shirayama, M; Takahashi, M, 2013) |
| "Since AT1R blockers are widely used to treat hypertension, we undertook a detailed analysis of potential miRNAs involved in Angiotensin II (AngII) mediated hypertension in rats and hypertensive patients, using miRNA microarray and qPCR analysis." | ( Andersen, DC; Bie, P; Eskildsen, TV; Hansen, ML; Hansen, PB; Jensen, CH; Jeppesen, PL; Marcussen, N; Nossent, AY; Rasmussen, LM; Sandberg, MB; Schneider, M; Sheikh, SP, 2013) |
| "L-NAME-treated rats had hypertension, lower urinary and renal NO indices, higher renal cortical levels of TBARS, GSSG and GSSG/GSH." | ( Joo Turoni, C; Juncos, LA; Karbiner, S; Marañon, RO; Peral de Bruno, M; Romero, D, 2014) |
| "Pirfenidone may be useful in the treatment of hypertension-induced myocardial fibrosis by inhibiting NLRP3-induced inflammation and fibrosis." | ( Chen, J; Li, H; Wang, Y; Wu, Y; Zhao, S, 2013) |
| "Effective treatment of hypertension is imperative for primary care." | ( Alajbegovic, A; Alajbegovic, L; Alajbegovic, S; Ambeskovic, M; Deljo, D; Sukalo, A; Vranic, JD, 2013) |
| "Apparent treatment-resistant hypertension is defined as systolic/diastolic BP ≥ 140/90 mmHg with concurrent use of three or more antihypertensive medication classes or use of four or more antihypertensive medication classes regardless of BP level." | ( Bell, EK; Bowling, CB; Calhoun, DA; Gutiérrez, OM; Irvin, MR; Lackland, DT; Muntner, P; Oparil, S; Tanner, RM; Warnock, D, 2013) |
| "The prevalence of apparent treatment-resistant hypertension among Reasons for Geographic and Racial Differences in Stroke study participants treated for hypertension (n=10,700) was determined by level of estimated GFR and albumin-to-creatinine ratio, and correlates of apparent treatment-resistant hypertension among those participants with CKD were evaluated." | ( Bell, EK; Bowling, CB; Calhoun, DA; Gutiérrez, OM; Irvin, MR; Lackland, DT; Muntner, P; Oparil, S; Tanner, RM; Warnock, D, 2013) |
| "The prevalence of apparent treatment-resistant hypertension was 15." | ( Bell, EK; Bowling, CB; Calhoun, DA; Gutiérrez, OM; Irvin, MR; Lackland, DT; Muntner, P; Oparil, S; Tanner, RM; Warnock, D, 2013) |
| "Pharmacologic therapy is a mainstay of treatment for hypertension, with angiotensin-converting enzyme (ACE) inhibitors being a frequently prescribed class of drugs." | ( Thoma, A, 2013) |
| "In the treatment of hypertension, once-daily administration of long-acting antihypertensive drugs has been recommended for the improvement of treatment adherence; however, it is unclear whether dividing daily doses has the additional benefit of more ideal blood pressure (BP) control over a 24-hour period." | ( Higaki, J; Irita, J; Masanori, J; Miyoshi, K; Nagao, T; Okura, T, 2013) |
| "In case of non-treated hypertension several medications and their combinations were studied (captopril, and moxonidine as such, captopril + nifedipine, captopril + moxonidine)." | ( Chiritso, MM; Grishin, OV; Ruksin, VV, 2013) |
| "A total of 48 patients with untreated hypertension were randomly assigned to irbesartan (ARB group, n=26) and amlodipine (CCB group, n=22)." | ( Fujiwara, S; Fukui, M; Goda, A; Hirotani, S; Komamura, K; Koshiba, M; Lee-Kawabata, M; Masaki, M; Masuyama, T; Nakabo, A; Otsuka, M; Sugahara, M; Tsujino, T, 2014) |
| "In 198 patients with untreated essential hypertension free of clinically relevant cardiovascular complications, we measured plasma levels of fibrinogen, prothrombin fragment 1 + 2, D-dimer, plasminogen activator inhibitor-1, and tissue plasminogen activator, and performed conventional echocardiography and TDI." | ( Catena, C; Colussi, G; Fedrizzi, S; Sechi, LA, 2013) |
| "Increasingly, apparent treatment-resistant hypertension has been recognized." | ( Bangalore, S; Deedwania, P; Demicco, DA; Fayyad, R; Kostis, JB; Laskey, R; Messerli, FH, 2014) |
| "Apparent treatment-resistant hypertension was defined as blood pressure ≥ 140 mm Hg despite 3 antihypertensive agents or <140 mm Hg with ≥ 4 antihypertensive agents." | ( Bangalore, S; Deedwania, P; Demicco, DA; Fayyad, R; Kostis, JB; Laskey, R; Messerli, FH, 2014) |
| "In addition, patients with apparent treatment-resistant hypertension had a 71% increase in major coronary event (P < ." | ( Bangalore, S; Deedwania, P; Demicco, DA; Fayyad, R; Kostis, JB; Laskey, R; Messerli, FH, 2014) |
| "To report a case of difficult-to-treat hypertension ultimately managed with triple antirenin (anti-R) therapy using plasma renin activity (PRA) to guide medication selection." | ( Coakley, C; Hough, A; Parra, D; Shah, S, 2014) |
| "To report a case of difficult-to-treat hypertension ultimately managed with triple antirenin (anti-R) therapy using plasma renin activity (PRA) to guide medication selection." | ( Coakley, C; Hough, A; Parra, D; Shah, S, 2013) |
| "UCP2 could be a useful target in treating hypertension-related vascular events." | ( Gao, Y; Huang, Y; Lau, CW; Liu, J; Liu, L; Ng, CF; Tian, XY; Wong, WT; Xu, A; Xu, G; Yao, X, 2014) |
| "Active treatment of hypertension with adequate control of blood pressure (BP) can prevent complications, improve life quality and increase life expectancy." | ( Bregvadze, TR; Mishchuk, NE; Tseluĭko, VI, 2013) |
| "Two-thirds of women treated had their hypertension controlled, irrespective of urban/rural setting or wealth." | ( Agrawal, S; Davey Smith, G; Ebrahim, S; Moser, KA, 2014) |
| "Chronic hydroxychloroquine treatment reduced hypertension, endothelial dysfunction, and organ damage in severe lupus mice, despite the persistent elevation of anti-double-stranded DNA, suggesting the involvement of new additional mechanisms to improve cardiovascular complications." | ( Algieri, F; Duarte, J; Gálvez, J; Gómez-Guzmán, M; Gómez-Morales, M; Jiménez, R; López-Farré, AJ; O'Valle, F; Pérez-Vizcaino, F; Romero, M; Sabio, JM; Sánchez, M; Zarzuelo, MJ, 2014) |
| "(Nitrariaceae) is used to treat hypertension." | ( Aisa, HA; Bakri, M; Chen, LD; Wang, MH; Yi, Y, 2014) |
| "However, the clinical application to treat hypertension was disappointing because of the side effects, including liver toxicity and fluid retention." | ( Emoto, N; Miyagawa, K, 2014) |
| "Apparent treatment-resistant hypertension (aTRH), defined as uncontrolled blood pressure using 3 or more antihypertensive medications or controlled using 4 or more antihypertensive medications, affects approximately 30% of uncontrolled and 12% of controlled blood pressure (BP) patients." | ( Egan, BM; Li, J, 2014) |
| "Other than treatment for weight loss, treatment of hypertension with specific antihypertensive medications that block or reduce aldosterone action are appropriate in obese patients." | ( Flynn, C, 2014) |
| "Spironolactone is often used to treat hypertension caused by hyperaldosteronism, and as a result, can form concentrically laminated electron dense spironolactone body inclusions within the adrenal gland." | ( Calomeni, EP; Nadasdy, T; Patel, KA; Zynger, DL, 2014) |
| "In patients with newly diagnosed untreated grade I-II hypertension, EEG oscillations were recorded under conditions activation of the two basic motivational systems, defensive motivational system and positive reinforcement system, evoked by recall of personally meaningful emotional events." | ( Aftanas, LI; Brak, IV; Gilinskaya, OM; Korenek, VV; Pavlov, SV; Reva, NV, 2014) |
| "A possible treatment choice used to treat acute hypertension is nitroglycerin ointment." | ( Brower, KA; Garcia, NA; Smith, HL; Wall, GC, 2015) |
| "Although, several drugs are used to treat hypertension, the success of the antihypertensive therapy is limited." | ( Akcali, KC; Ayaloglu-Butun, F; Demirel-Yilmaz, E; Han, S; Uludag, MO; Usanmaz, SE, 2015) |
| "A total of 182 individuals with never-treated essential hypertension and 182 age-matched healthy controls were studied." | ( Wang, X; Xia, W; Xu, L; Xu, W; Yao, Y, 2015) |
| "In the treatment of hypertension, berberine with lifestyle intervention tended to lower the level of blood pressure more than the lifestyle intervention alone or placebo did; The same occurred when berberine combined with oral hypotensor was compared to the same hypotensor." | ( Dong, F; Fan, J; Lan, J; Sun, G; Yan, Z; Zhao, Y; Zheng, W, 2015) |
| "Combination treatments for hypertension most often include a renin-angiotensin-aldosterone system (RAAS) inhibitor." | ( Boully, C; Caillard, L; Chaussade, E; Cochiello, S; Hanon, O; Labourée, F, 2015) |
| "In patients with uncontrolled or untreated hypertension, alfuzosin 10 mg alone or combined with antihypertensive therapy significantly decreased systolic and diastolic BP." | ( Chung, WS; Hyun, JS; Kim, SW; Lee, SW; Min, KS; Moon, DG; Moon, KH; Park, JK; Park, K; Ryu, JK; Yang, DY; Yang, SK; Zhang, LT, 2015) |
| "For example, Chinese medical treatment of hypertension, high blood lipids, increased transaminase, and so on candirectly use Chinese recipes, but no longer with syndrome differentiation." | ( Zheng, ZJ, 2015) |
| "In elderly persons with treated hypertension, a rapid decline in eGFR is associated with a higher risk of mortality." | ( Ademi, Z; Chowdhury, EK; Krum, H; Langham, RG; Nelson, MR; Owen, A; Reid, CM; Wing, LM, 2015) |
| "Oral clonidine is used to treat hypertension but often produces sedation and severe dry mouth; intrathecal clonidine is used to treat chronic pain but may produce hypotension." | ( D'Angelo, R; Hildebrand, KR; Hong, KS; Komanski, CB; North, JM; Rauck, RL, 2015) |
| "Future development of DNA vaccine to treat hypertension may provide a new therapeutic option to treat hypertension." | ( Katsuya, T; Koriyama, H; Kurinami, H; Kyutoku, M; Morishita, R; Nakagami, F; Nakagami, H; Osako, MK; Rakugi, H; Shimamura, M, 2015) |
| "This agent could be useful for the treatment of hypertension, cardiovascular and renal disorders." | ( Aoki, K; Arai, K; Homma, T; Ishikawa, H; Mizuno, M; Morikawa, Y; Sada, T; Tsuruoka, H; Ubukata, N, 2015) |
| "It is important to know how to treat hypertension in patients with coronary artery disease (CAD)." | ( Aronow, WS, 2016) |
| "Ninety-one patients with untreated hypertension underwent a home sleep study (55 were found to have OSA; 36 were not)." | ( Manhem, K; Peker, Y; Rosengren, A; Thunström, E, 2016) |
| "In long-term hemodialysis patients, treating hypertension using home BP measurements may improve well-being." | ( Agarwal, R, 2016) |
| "ROPC for medications to treat hypertension and hyperlipidemia is effective in increasing medication adherence, and, thus, improving blood pressure and cholesterol outcomes." | ( Acharya, SD; Braun, LT; Finnie, RK; Goetzel, RZ; Hopkins, DP; Jacob, V; Kottke, TE; Lackland, DT; Njie, GJ; Proia, KK; Pronk, NP; Rask, KJ, 2015) |
| "widely used in southeastern Asia for treating hypertension." | ( Chen, L; Gao, XM; Geng, X; Li, CX; Liu, F; Ma, YK; Mao, HP; Qiu, LZ; Qu, JT; Wang, H; Yang, Y; Zhang, DX; Zhang, JM, 2015) |
| "Baseline prevalence of apparent treatment-resistant hypertension and of controlled and uncontrolled nonresistant hypertension, were 6." | ( Berr, C; Helmer, C; Kaboré, J; Massy, ZA; Metzger, M; Stengel, B; Tzourio, C, 2016) |
| "We studied 62 patients with untreated hypertension, randomly assigned to cilnidipine or amlodipine for 48 weeks." | ( Eguchi, A; Fujiwara, S; Hirotani, S; Komamura, K; Koshiba, M; Mano, T; Masaki, M; Masuyama, T; Sugahara, M; Tsujino, T, 2016) |
| "Patients with treatment-naïve hypertension or uncontrolled hypertension who were on non-ARB therapy were eligible for inclusion." | ( Chin, AM; Sule, AA; Tay, JC; Teong, HH, 2016) |
| "Aggressive treatment of hypertension resulted in complete resolution of the clinical and radiologic features of the syndrome." | ( Argyropoulou, MI; Christopoulou, F; Elisaf, M; Kosta, P; Rizos, EC, 2016) |
| "The dilemmas involved in treating hypertension caused by dexmedetomidine are discussed." | ( Balaji, S; Mathews, L; Moni, A; Muthiah, T, 2016) |
| "Uncontrolled treatment-resistant hypertension (TRH), i." | ( Cook, AG; Davis, RA; Egan, BM; Fleming, DO; Hester, WH; Jebaily, GC; Jones, KW; Laken, MA; Qanungo, S; Sutherland, SE; Valainis, GT; Way, CF; Wright, MB, 2016) |
| "Thus, potential pharmacological treatments for hypertension should be examined as modulators of these two metabolic systems." | ( Bielawska, K; Biernacki, M; Gęgotek, A; Skrzydlewska, E; Toczek, M; Łuczaj, W, 2016) |
| "Evidence for treating hypertension in patients with asymptomatic aortic valve stenosis is scarce." | ( Boman, K; Greve, AM; Kesäniemi, YA; Nielsen, OW; Nienaber, CA; Olsen, MH; Pedersen, TR; Sabbah, M; Sajadieh, A; Wachtell, K; Willenheimer, R, 2016) |
| "Among the treatments for hypertension, O." | ( Ahmad, M; Ruan, S; Tan, CS; Yam, MF, 2016) |
| "Barriers to diagnosis and treatment of hypertension may differ regionally according to economic development." | ( Alim, M; Arabshahi, S; Chow, C; D'Esposito, F; Evans, RG; Guggilla, RK; Joshi, R; Kalyanram, K; Kartik, K; Mahal, A; Maulik, PK; Mini, GK; Oldenburg, B; Riddell, MA; Sathish, T; Srikanth, VK; Suresh, O; Thankappan, KR; Thomas, N; Thrift, AG; Varma, RP, 2016) |
| "A 69-year-old woman undergoing treatment for hypertension and epilepsy was scheduled to undergo cataract surgery." | ( Furuichi, Y; Hamada, A; Kobayashi, K; Nakazato, K; Sakamoto, A, 2016) |
| "Exercise is a major nonpharmacological treatment for hypertension, but its underlying mechanisms are still not completely elucidated." | ( Fu, J; Han, Y; Jose, PA; Liu, Y; Wang, J; Zeng, C; Zheng, S; Zhou, L, 2016) |
| "The costs of drug treatment for hypertension were calculated and general estimation, whereas effectiveness was measured as a reduction in SBP and DBP at the end of a 24-week study period." | ( Chen, Z; Hao, G; Li, Y; Ma, L; Wang, X; Wang, Z; Zhang, L; Zhao, X; Zhu, M, 2017) |
| "Although hypertension guidelines define treatment-resistant hypertension as blood pressure uncontrolled by ≥3 antihypertensive medications, including a diuretic, it is unknown whether patient prognosis differs when a diuretic is included." | ( Bangalore, S; Black, HR; Calhoun, DA; Cushman, WC; Davis, BR; Kostis, JB; Muntner, PM; Pressel, SL; Probstfield, JL; Rahman, M; Whelton, PK, 2017) |
| "The prevalence of treatment-resistant hypertension and its association with ALLHAT primary (combined fatal coronary heart disease or nonfatal myocardial infarction) and secondary (all-cause mortality, stroke, heart failure, combined coronary heart disease, and combined cardiovascular disease) outcomes were identified for each treatment group." | ( Bangalore, S; Black, HR; Calhoun, DA; Cushman, WC; Davis, BR; Kostis, JB; Muntner, PM; Pressel, SL; Probstfield, JL; Rahman, M; Whelton, PK, 2017) |
| "However, prognoses in those with treatment-resistant hypertension were similar across treatment groups." | ( Bangalore, S; Black, HR; Calhoun, DA; Cushman, WC; Davis, BR; Kostis, JB; Muntner, PM; Pressel, SL; Probstfield, JL; Rahman, M; Whelton, PK, 2017) |
| "The high burden of undetected and undertreated hypertension and diabetes mellitus is a major health challenge worldwide." | ( Ajay, VS; Jindal, D; Kinra, S; Pawar, A; Prabhakaran, D; Roy, A; Sharma, R; Tandon, N; Venugopal, V, 2016) |
| "The patients received routine treatment for hypertension and CAD." | ( Asadikaram, G; Ebrahimi, N; Kazemi Arababadi, M; Kiani, Z; Kohan, F; Masoumi, M; Nasiri, AA; Sepehri, Z; Sheikh Fathollahi, M, 2016) |
| "Factors associated with treatment of hypertension were having had BP measured within the previous year (OR 6." | ( Arabshahi, S; Busingye, D; Evans, RG; Kalyanram, K; Kartik, K; Riddell, MA; Srikanth, VK; Suresh, O; Thrift, AG; Zhu, X, 2017) |
| "Diuretics have been used for years to treat hypertension as both a monotherapy and in combination." | ( Asil, S; Atalar, E, 2017) |
| "Pharmacological treatment of prehypertension may ameliorate hypertension and improve vascular structure and function." | ( He, DH; Lin, JX; Xie, Q; Xu, CS; Zhang, LM, 2017) |
| "Participants with untreated hypertension were enrolled from four centres in the community of western Sydney, NSW, Australia, mainly by general practitioners." | ( Atkins, E; Bennett, A; Burke, M; Chalmers, J; Chou, M; Chow, CK; Dehbi, HM; Hillis, G; Hilmer, S; Krum, H; Neal, B; Nelson, M; Patel, A; Peiris, D; Reid, CM; Rodgers, A; Rogers, K; Salam, A; Thakkar, J; Thom, S; Usherwood, T; Vo, K; Webster, R; Woodward, M, 2017) |
| "In patients with newly diagnosed, untreated hypertension, regular fish consumption was accompanied by lower blood pressure." | ( Bagge, CN; Christensen, JH; Schmidt, EB; Skov, CM; Strandhave, C; Svensson, M, 2017) |
| "To assess the compliance to treatment of hypertension and diabetes amongst the diagnosed patients from rural area and to study reasons of non-compliance and knowledge and attitude." | ( Kakumani, KV; Waingankar, P, 2016) |
| "Unsuccessfully treated hypertension was defined as daytime ambulatory BP of at least 135/85 mm Hg and was further divided into masked and sustained hypertension." | ( Brisson, C; Dalens, V; Duchaine, C; Gilbert-Ouimet, M; Guénette, L; Milot, A; Trudel, X, 2017) |
| ": To treat hypertension, combining two or more antihypertensive drugs from different classes is often necessary." | ( Cockcroft, JR; Giles, TD; Jakate, A; Pitt, B; Wright, HM, 2017) |
| "Indeed, treatment of hypertension represents a key strategy for preventing coronary artery disease, stroke, congestive heart failure and cardiovascular death." | ( Battistoni, A; Coluccia, R; Mastromarino, V; Santolamazza, C; Tocci, G; Volpe, M, 2017) |
| "A novel therapeutic approach for treating resistant hypertension could be the use of bioelectronic medicines to achieve blood pressure (BP) control in implanted patients by closed-loop stimulation of the left vagus nerve (LVN)." | ( Nielsen, TN; Sevcencu, C; Struijk, JJ, 2017) |
| "Adults seeking treatment for hypertension were recruited." | ( Paradkar, SG; Sinha, SR, 2018) |
| "Enalapril is a common drug for the treatment of hypertension in Ethiopia." | ( Alemayehu, C; Aseffa, A; Clavarino, A; McGree, J; Mitchell, G; Nikles, J, 2017) |
| "In the treatment of hypertension avoiding adverse cardiovascular complications to achieve target blood pressure is essential." | ( Ferenci, T; Simonyi, G, 2017) |
| "Diazoxide is a drug used in the treatment of hypertension however, its effect on 5-hydroxyindole acetic acid (5-HIAA) and dopamine amines in adult animal models remains unclear." | ( Brizuela, NO; Guzmán, DC; Herrera, MO; Mejía, GB; Olguín, HJ; Peraza, AV, 2017) |
| "NaHS treatment decreased hypertension-induced Cx40/Cx43 expressions in T lymphocytes from SHR." | ( Li, L; Li, XZ; Ma, KT; Ni, X; Peng, M; Shan, LY; Shen, TW; Si, JQ; Yu, XS; Zhang, L, 2018) |
| "Nicardipine is frequently used in the treatment of hypertension for patients with acute stroke; however, its dosing is complicated by a high risk of phlebitis." | ( Kawada, K; Miyamoto, N; Ohta, T; Tanaka, K, 2018) |
| "This exploratory analysis examined treatment-emergent hypertension (TE-HTN) and its relation with lenvatinib efficacy and safety in SELECT." | ( Brose, MS; Dutcus, CE; Francis, S; Guo, M; Habra, MA; Kiyota, N; Mathias, E; Newbold, K; Robinson, B; Schlumberger, M; Sherman, SI; Tahara, M; Wirth, LJ, 2018) |
| "Choosing a method of treating arterial hypertension remains an urgent problem today." | ( Davydenko, I; Maruschak, A; Shorikov, E; Slobodyan, K; Timofiichuk, I, 2018) |
| "Several options are available for the treatment of hypertension; however, many treated patients are still not below blood pressure (BP) target." | ( Abreu, P; Beckerman, B; Burgess, E; Fernet, M; Lins, K; Vincent, J, 2018) |
| "One common AE of this treatment is hypertension, known to be associated with cardiovascular disease and can therefore potentially worsen the well-being of the treated patients." | ( Bauer, J; Grimm, D; Grosse, J; Infanger, M; Kopp, S; Krüger, M; Milling, RV; Wehland, M, 2018) |
| "Of these 300 patients, 201 (67%) were treated with hypertension induction and 99 were not." | ( Coert, BA; Gathier, CS; Haegens, NM; Horn, J; van den Bergh, WM; Verbaan, D, 2018) |
| "All physicians who treat hypertension should routinely screen appropriate patients for PA." | ( Auchus, RJ; Byrd, JB; Turcu, AF, 2018) |
| "Immediate vasodilator treatment for the hypertension and non-invasive posi- tive pressure ventilation for the hypoxia were commenced." | ( Kakinohana, M; Nakamura, S; Noguchi, N; Tobaru, S, 2016) |
| "Acute treatment of severe hypertension produced unpredictable and potentially dangerous responses in SBP." | ( Afshartous, D; Arciniegas, R; Bernstein, J; DeGraff, S; Materson, BJ; Preston, RA, 2019) |
| "Efficacy of telmisartan in treating hypertension (HT) in cats has not been largely investigated." | ( Albrecht, B; Elliott, J; Glaus, TM; Herberich, E; Zimmering, T, 2019) |
| "The main objective of treatment against hypertension is not only to reduce blood pressure levels, but also to reduce vascular risk in general." | ( Aguilar, MI; Alegría-Herrera, E; Avilés-Flores, M; Fuentes-Mata, M; Herrera-Ruiz, M; Jiménez-Ferrer, E; Román-Ramos, R; Santillán-Urquiza, MA; Zamilpa, A, 2019) |
| "Successful prevention and treatment of hypertension depend on the appropriate combination of antihypertensive drug therapy and nondrug lifestyle modification." | ( Chen, H; Guo, XY; Higashino, H; Huang, TL; Liu, YH; Liu, YX; Lu, Q; Okamura, H; Wang, SM; Yamanishi, H; Yamanishi, K; Zhang, R; Zhang, SQ; Zhang, WH; Zhang, Y; Zhou, JW; Zou, YY, 2019) |
| "Evidence related to the treatment of hypertension through sources of inorganic nitrate has been presented." | ( Remington, J; Winters, K, 2019) |
| "S-amlodipine has been broadly used to treat hypertension, but its protective effects and underlying mechanism remain controversial." | ( He, C; Si, D; Yang, J; Yang, P; Zhao, Y, 2019) |
| "To prevent and treat hypertension, it is important to restrict salt in one's diet since adolescence." | ( Enjoji, M; Horita, N; Morita, R; Murata, Y; Ohe, K; Tsuchihashi, T; Umeki, Y; Yasutake, K, 2019) |
| "Background Amlodipine is used for the treatment of hypertension, but reports on its use in early pregnancy are limited." | ( Arata, N; Ito, S; Kamiya, CA; Mikami, M; Mito, A; Miyasato-Isoda, M; Murashima, A; Suzuki, T; Wada, Y; Waguri, M; Watanabe, O; Yakuwa, N; Yoshimatsu, J, 2019) |
| "9 weeks of dapagliflozin treatment decreases hypertension and reverses LV concentric remodeling in HFpEF pigs partly by restraining sympathetic tone in the aorta, leading to inhibition of the inflammatory response and NO-cGMP-PKG pathway activation." | ( Feng, B; Ma, X; Sun, K; Xu, G; Zhang, N; Zhou, Y, 2019) |
| "We can treat hypertension more effectively by getting the blood pressure measurement right, understanding the link between albuminuria and hypertension, enabling the use of spironolactone to treat resistant hypertension through the use of drugs that bind potassium in the gut, and addressing the structural determinants of health." | ( Agarwal, R, 2019) |
| "The goals of treatment in hypertension are to optimally control high blood pressure and to reduce associated cardiovascular morbidity and mortality using the most suitable therapy available." | ( Dineva, S; Filipova, E; Kalinov, K; Pavlova, V; Uzunova, K; Vekov, T, 2019) |
| "In SA, >50% of patients treated for hypertension are not controlled." | ( Bryer, A; Mpe, MT; Rayner, BL; Spence, JD, 2019) |
| "Among those treated for hypertension, 73." | ( Angell, SY; Bartley, K; Chamany, S; Elfassy, T; Yi, SS, 2020) |
| "Efficient treatment of hypertension is vital." | ( Wang, L; Wu, W, 2019) |
| "In particular, apparent treatment-resistant hypertension (systolic blood pressure ≥140 mm Hg or diastolic blood pressure ≥90 mm Hg on 3 antihypertensive medications or use of ≥4 antihypertensive medications) and the count of antihypertensive medication classes significantly reduced the effect of hyperuricemia on ischemic stroke." | ( Bridges, SL; Chaudhary, NS; Colantonio, LD; Curtis, JR; Cushman, M; Flaherty, ML; Gaffo, A; Howard, G; Irvin, MR; Judd, S; Levitan, EB; Limdi, NA; Rahn, EJ; Reynolds, RJ; Saag, KG; Singh, JA, 2020) |
| "Diuretics are pivotal drugs for the treatment of hypertension." | ( Bottino, LG; Ferrari, F; Fuchs, FD; Fuchs, SC; Helal, L; Martins, VM, 2019) |
| "Response to acute treatment of severe hypertension during pregnancy in Asian women was not known." | ( Chera-Aree, P; Leetheeragul, J; Sampaojarean, U; Surasereewong, S; Tengtrakulcharoen, P; Wataganara, T, 2020) |
| "In addition, treating chronic hypertension neither reduces nor increases fetal or newborn death or morbidity, regardless of the gestational age at which the antihypertensive treatment is started." | ( Kametas, N; Khalil, A; Magee, LA; von Dadelszen, P, 2022) |
| "Traditional short-acting infusions to treat hypertension, such as sodium nitroprusside, may lead to accumulation of toxic metabolites in patients with renal dysfunction." | ( Jahadi, O; Kwiatkowski, DM; Moss, J; Rosenthal, DN; Ryan, KR; Wu, M, 2020) |
| "Esaxerenone was approved for the treatment of hypertension in Japan in January 2019." | ( Homma, T; Igawa, Y; Yamada, M; Yamakawa, S; Yoshimura, M, 2020) |
| "Beta-blockers are commonly used in the treatment of hypertension." | ( Dormuth, C; Musini, VM; Soufi, S; Zhang, XY, 2020) |
| "Drugs used in the treatment of hypertension and diabetes influence the risk of development of COVID-19, but, not its severity." | ( Aithal, GP; Cai, T; Du, J; Hu, Y; Huang, K; Jiang, F; Jin, S; Liang, L; Tan, X; Valdes, AM; Vijay, A; Wang, H; Wang, S; Yan, H; Yang, S; Zhang, S; Zheng, N, 2020) |
| "Triplixam is used to treat systemic hypertension and contains amlodipine, indapamide and perindopril arginine as active ingredients which might have induced the sudden myopia." | ( Jaruseviciene, R; Sirvydyte, G, 2020) |
| "The Quadruple UltrA-low-dose tReaTment for hypErTension (QUARTET) double-blind, active-controlled, randomized clinical trial will examine whether ultra-low-dose quadruple combination therapy is more effective than guideline-recommended standard care in lowering blood pressure." | ( Atkins, ER; Billot, L; Chalmers, J; Chow, CK; Hay, P; Hillis, GS; Neal, B; Nelson, M; Patel, A; Reid, CM; Rodgers, A; Schlaich, M; Usherwood, T; Webster, R, 2021) |
| "In each study, patients already treated for hypertension were switched to Per/Ind 10/2." | ( Brzozowska-Villatte, R; Dézsi, CA; Farsang, C; Glezer, M; Karpov, Y, 2021) |
| "All major guidelines on treatment of hypertension recommend weight loss; anti-obesity drugs may be able to help in this respect." | ( Berghold, A; Horvath, K; Jeitler, K; Krenn, C; Semlitsch, T; Siebenhofer, A; Winterholer, S, 2021) |
| "(Lamiaceae) leaves are used to treat hypertension in Ethiopian folk medicine." | ( Abebe, A; Degu, A; Engidawork, E, 2021) |
| "These gaps in the available treatment for hypertension require further investigation of the development of safe and effective therapies." | ( Bhat, A; Dhar, A; Ghatage, T; Goyal, SG, 2021) |
| "In 20 non-diabetic patients with true treatment-resistant hypertension, ambulatory and office BP were measured after witnessed intake of medications prior to, six and 24 months after RDN." | ( Fuskevåg, OM; Gjessing, PF; Hanssen, TA; Miroslawska, AK; Norvik, JV; Solbu, MD; Steigen, TK, 2021) |
| "is used in folk medicine to treat hypertension." | ( Alamgeer, -; Alharbi, KS; Alotaibi, NH; Bukhari, SNA; Irfan, HM; Saleem, M; Sharif, A; Younis, W, 2020) |
| "is used traditionally to treat hypertension but no scientific literature supports this claim." | ( Alamgeer, -; Alharbi, KS; Alotaibi, NH; Irfan, HM; Nasir Abbas, SB; Saleem, M; Sharif, A, 2020) |
| "Unless convincing studies on treatment of hypertension after renal transplantation are available, the ESC/ESH Guidelines 2018 should apply for these patients." | ( Chatzikyrkou, C; Schiffer, M; Schmieder, RE, 2021) |
| "Finding the right medical therapy in treating hypertension, especially RH, is commonly onerous when it comes to achieving BP targets, avoiding medication side effects, and aiming for the best outcomes." | ( Alqudsi, M; Navarrete, J; Velez, JCQ, 2021) |
| "To decide whether to apply an ARNI to treat hypertension clinically, it is important to understand the potential properties of the drug in modulating multiple factors inside and outside the cardiovascular system beyond its effect on reducing peripheral blood pressure." | ( Rakugi, H; Yamamoto, K, 2021) |
| "Unfortunately, treatment of hypertension is still suboptimal worldwide." | ( Gallo, G; Rubattu, S, 2022) |
| "In the treatment of hypertension and chronic heart failure, sacubitril valsartan can improve the clinical symptoms of patients to the greatest extent and can significantly improve the levels of LVEF, LVEDD, NT-proBNP, heart function, and other indicators." | ( Du, H; Jiang, N; Li, X; Zhao, W, 2022) |
| "SAC/VAL treatment improved hypertension-induced sexual dysfunction, exhibited as a prolonged estrus phase, increased receptivity and proceptive events, and decreased aggressive events, compared with those of VAL treatment and control SHRs without treatments." | ( Qi, M; Sun, R; Wang, W; Yi, G; Yu, J; Zhuang, C, 2022) |
| "Awareness and treatment of hypertension in high-risk occupation are recommended." | ( Goyal, AK; Mohanty, SK; Shekhar, P, 2022) |
| "CCBs are an important modality in treating hypertension." | ( Matok, I; Rabkin, N; Rotshild, V, 2023) |
| "Although awareness and treatment rates of hypertension have significantly improved in recent years, the prevalence of undiagnosed and untreated hypertension remains a major public health concern for Indian policymakers." | ( Banerjee, S; Boro, B, 2022) |
| "In the case of undertreated hypertension, education, comorbidities, and tobacco consumption were the major contributors to the urban-rural inequality, which accounted for 12." | ( Banerjee, S; Boro, B, 2022) |
| "Yet, in particular, for the treatment of hypertension, the number of patients with uncontrolled hypertension continues to rise, either due to patient noncompliance or because of the significant renin rises that may, at least partially, overcome the effect of RAS blockade (RAS escape)." | ( Cruz-López, EO; Danser, AHJ; Lu, HS; Mirabito Colafella, KM; Uijl, E; Wu, C; Ye, D, 2022) |
| "In the context of nonpharmacological treatment of hypertension, sodium restriction plays an important role." | ( Zidek, W, 2022) |
| "Hydralazine is a vasodilator used to treat hypertension, pre-eclampsia, and heart failure." | ( Alqahtani, F; Ashraf, W; Hussain, I; Imran, I; Khalid, S; Majeed, A; Rasool, MF; Rehman, AU; Saeed, H; Shahzad Qamar, A; Zamir, A, 2022) |
| "Patients with treatment-resistant hypertension who received baxdrostat had dose-related reductions in blood pressure." | ( Alp, N; Bhatt, DL; Brown, MJ; Freeman, MW; Halvorsen, YD; Isaacsohn, J; Marshall, W; Murphy, B; Pater, M; Pearce, C; Srivastava, A, 2023) |
| "Butyric acid is a potential target in treating hypertension." | ( Chen, TT; Chen, WJ; Huang, H; Jin, R; Tang, YH; Wang, XL; Wei, J; Xu, X; Zou, CW, 2023) |
| "Butyric acid is a potential target in treating hypertension." | ( Chen, TT; Chen, WJ; Huang, H; Jin, R; Tang, YH; Wang, XL; Wei, J; Xu, X; Zou, CW, 2023) |
| "The mechanism of isorhynchophylline treating hypertension is not only the regulation of serum neurotransmitters rhythm, but also acting on rhythm genes in the feedback loop of the central biological clock." | ( Jiang, H; Li, C; Li, Y; Liu, Y; Sun, M; Wang, D; Wang, L, 2023) |
| "Diuretics are commonly used for the treatment of hypertension." | ( Cheung, BMY; Lin, Z; Tang, V; Tsoi, MF, 2023) |
| "We conclude that using indapamide to treat hypertension is safe, even in the elderly, especially if the sustained-release formulation is used and electrolytes are monitored periodically." | ( Cheung, BMY; Lin, Z; Tang, V; Tsoi, MF, 2023) |
| "Apparent treatment-resistant hypertension (aTRH) was defined as a SBP ≥ 140 mmHg or DBP ≥ 90 mmHg with concurrent use of three classes of antihypertensive medications, or taking four or more classes of antihypertensive medication regardless of BP level." | ( Bridges, SL; Chaudary, N; Colantonio, LD; Cushman, M; Howard, G; Irvin, MR; Limdi, N; Merriman, TR; Muntner, P; Reynolds, RJ; Saag, K; Tanner, RM, 2023) |
| "Although true treatment resistant hypertension is relatively rare (about 7." | ( Anđelković, B; Cvjetan, R; Gocić Petrović, R; Janković, SM; Kostić, T; Petrović, M; Radovanović, S; Ratković, N; Rihor, B; Spiroski, D; Stanković, A; Stojković, S; Zdravković, M, 2023) |
| "For patients with treatment-resistant hypertension, guidelines recommend the addition of spironolactone to the baseline antihypertensive regimen." | ( Agarwal, R; Georgianos, PI, 2023) |
| "Although various agents for treatment of hypertension exert significant effects, there is currently no effective treatment for hypertensive nephropathy." | ( Du, J; Fang, Q; He, J; Long, X; Tan, F; Wang, J; Wang, Y; Wei, J; Yuan, X, 2023) |
| "Participants with ADPKD and treated hypertension (n = 60) will be randomly allocated (1:1) to receive a daily dose of either nitrate-replete (400 mg nitrate/day) or nitrate-deplete BRJ for 4 weeks." | ( Chau, K; Elhindi, J; Harris, DC; Lee, V; Munt, A; Nguyen, B; Rangan, GK; Sagar, PS; Saravanabavan, S; Sud, K; Vahedi, FA; Wong, N, 2023) |
| "Patients with treatment resistant hypertension (TRH) are at particular risk of cardiovascular disease." | ( Bech, JN; Hoffmann-Petersen, N; Hornstrup, BG; Lauridsen, TG, 2023) |
| "T2D patients on treatment without hypertension (n = 172), with hypertension (n = 177) and 191 healthy volunteers were recruited for the study." | ( Nanda, N; Pal, GK; Sailaja, AN; Suryanarayana, BS, 2023) |
| "Moreover, the pathology that is being treated (e." | ( Ak, HY; Haberal, İ; Koyuncu, AO; Yeşiltaş, MA, 2023) |
| "However, the RAS inhibitors used to treat hypertension may contribute to decreased mortality and improved clinical outcomes." | ( Hwang, HJ; Lee, TG, 2023) |