malic acid has been researched along with Hypertension in 3 studies
malic acid : A 2-hydroxydicarboxylic acid that is succinic acid in which one of the hydrogens attached to a carbon is replaced by a hydroxy group.
2-hydroxydicarboxylic acid : Any dicarboxylic acid carrying a hydroxy group on the carbon atom at position alpha to the carboxy group.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Angiotensin II (AngII)-induced superoxide (O2(•-)) production by the NADPH oxidases and mitochondria has been implicated in the pathogenesis of endothelial dysfunction and hypertension." | 7.80 | Nox2-induced production of mitochondrial superoxide in angiotensin II-mediated endothelial oxidative stress and hypertension. ( Bikineyeva, A; Dikalov, SI; Dikalova, AE; Griendling, KK; Harrison, DG; Hilenski, L; Lassègue, B; Nazarewicz, RR, 2014) |
| "Angiotensin II (AngII)-induced superoxide (O2(•-)) production by the NADPH oxidases and mitochondria has been implicated in the pathogenesis of endothelial dysfunction and hypertension." | 3.80 | Nox2-induced production of mitochondrial superoxide in angiotensin II-mediated endothelial oxidative stress and hypertension. ( Bikineyeva, A; Dikalov, SI; Dikalova, AE; Griendling, KK; Harrison, DG; Hilenski, L; Lassègue, B; Nazarewicz, RR, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hou, E | 1 |
| Sun, N | 1 |
| Zhang, F | 1 |
| Zhao, C | 1 |
| Usa, K | 2 |
| Liang, M | 2 |
| Tian, Z | 2 |
| Dikalov, SI | 1 |
| Nazarewicz, RR | 1 |
| Bikineyeva, A | 1 |
| Hilenski, L | 1 |
| Lassègue, B | 1 |
| Griendling, KK | 1 |
| Harrison, DG | 1 |
| Dikalova, AE | 1 |
| Liu, Y | 1 |
| Mladinov, D | 1 |
| Fang, Y | 1 |
| Ding, X | 1 |
| Greene, AS | 1 |
| Cowley, AW | 1 |
3 other studies available for malic acid and Hypertension
| Article | Year |
|---|---|
Malate and Aspartate Increase L-Arginine and Nitric Oxide and Attenuate Hypertension.
Topics: Animals; Arginine; Aspartic Acid; Down-Regulation; Fumarate Hydratase; Gene Knockdown Techniques; Hy | 2017 |
Nox2-induced production of mitochondrial superoxide in angiotensin II-mediated endothelial oxidative stress and hypertension.
Topics: Angiotensin II; Animals; CSK Tyrosine-Protein Kinase; Cyclic N-Oxides; Cytoplasm; Disease Models, An | 2014 |
Novel role of fumarate metabolism in dahl-salt sensitive hypertension.
Topics: Analysis of Variance; Animals; Biomarkers; Blotting, Western; Disease Models, Animal; DNA, Complemen | 2009 |