gliclazide has been researched along with Hypertension in 21 studies
Gliclazide: An oral sulfonylurea hypoglycemic agent which stimulates insulin secretion.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report a case of exposure to gliclazide and ramipril during pregnancy in a patient with diabetes mellitus and hypertension." | 7.75 | Normal pregnancy and healthy child after continued exposure to gliclazide and ramipril during pregnancy. ( Akar, M; Kolagasi, O; Sari, F; Sari, R, 2009) |
| "The subject is a diabetic and hypertensive woman treated early during an unplanned pregnancy with a multi-drug regimen that included three drugs with no prior history for use in pregnant women (rosiglitazone, gliclazide, atorvastatin)." | 7.72 | Normal pregnancy outcome following inadvertent exposure to rosiglitazone, gliclazide, and atorvastatin in a diabetic and hypertensive woman. ( Kadioglu, M; Kalyoncu, NI; Kesim, M; Ulku, C; Yaris, E; Yaris, F, 2004) |
| "In type 2 diabetic patients, the vasodilating response to forearm ischemia was the same whether patients were treated with diet treatment alone or with glibenclamide or glimepiride at blood glucose-lowering equipotent closes." | 5.09 | Sulfonylurea treatment of type 2 diabetic patients does not reduce the vasodilator response to ischemia. ( Brunelli, C; Cordera, R; Cordone, S; Olivotti, L; Rossettin, P; Schiavo, M; Spallarossa, P, 2001) |
| "To report a case of exposure to gliclazide and ramipril during pregnancy in a patient with diabetes mellitus and hypertension." | 3.75 | Normal pregnancy and healthy child after continued exposure to gliclazide and ramipril during pregnancy. ( Akar, M; Kolagasi, O; Sari, F; Sari, R, 2009) |
| "The subject is a diabetic and hypertensive woman treated early during an unplanned pregnancy with a multi-drug regimen that included three drugs with no prior history for use in pregnant women (rosiglitazone, gliclazide, atorvastatin)." | 3.72 | Normal pregnancy outcome following inadvertent exposure to rosiglitazone, gliclazide, and atorvastatin in a diabetic and hypertensive woman. ( Kadioglu, M; Kalyoncu, NI; Kesim, M; Ulku, C; Yaris, E; Yaris, F, 2004) |
| "Weight loss is strongly recommended for overweight and obese adults with type 2 diabetes." | 2.94 | The Risks of Cardiovascular Disease and Mortality Following Weight Change in Adults with Diabetes: Results from ADVANCE. ( Chalmers, J; Hamet, P; Harrap, S; Lee, AK; Marre, M; Mcevoy, JW; Ohkuma, T; Selvin, E; Sharrett, AR; Wang, D; Warren, B; Williams, B; Woodward, M, 2020) |
| "A total of 11 140 patients with type 2 diabetes mellitus were randomly assigned to fixed combination of perindopril-indapamide (4/1." | 2.79 | Effects of combination of perindopril, indapamide, and calcium channel blockers in patients with type 2 diabetes mellitus: results from the Action In Diabetes and Vascular Disease: Preterax and Diamicron Controlled Evaluation (ADVANCE) trial. ( Arima, H; Chalmers, J; Harrap, S; Hirakawa, Y; Mancia, G; Patel, A; Poulter, N; Williams, B; Woodward, M; Zoungas, S, 2014) |
| "In patients with type 2 diabetes, moderate alcohol use, particularly wine consumption, is associated with reduced risks of cardiovascular events and all-cause mortality." | 2.79 | The relationship between alcohol consumption and vascular complications and mortality in individuals with type 2 diabetes. ( Blomster, JI; Chalmers, J; Chow, CK; Harrap, S; Hillis, GS; Li, Q; Mancia, G; Neal, B; Patel, A; Poulter, N; Williams, B; Woodward, M; Zoungas, S, 2014) |
| "A post hoc analysis of patients with type 2 diabetes followed by the ADVANCE-ON (Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation - Observational Study)." | 1.72 | Cumulative Systolic Blood Pressure Load and Cardiovascular Risk in Patients With Diabetes. ( Chalmers, J; Hamet, P; Harrap, S; Harris, K; Mancia, G; Poulter, N; Rodgers, A; Wang, N; Williams, B; Woodward, M; Zoungas, S, 2022) |
| " Long-term use of metformin in complex multifactorial therapy of women with decompensated type 2 diabetes DM, AH and abdominal obesity provides improvement of carbohydrate and lipid metabolism, lowering of arterial pressure, diminishment of albuminuria, diastolic dysfunction, and stiffness of left ventricular myocardium." | 1.36 | [Dynamics of structural-functional parameters of cardiovascular system during use of complex therapy of women with type 2 diabetes mellitus]. ( Elsukova, OS; Onuchin, SG; Onuchina, EL; Solov'ev, OV, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 11 (52.38) | 29.6817 |
| 2010's | 7 (33.33) | 24.3611 |
| 2020's | 2 (9.52) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, N | 1 |
| Harris, K | 1 |
| Hamet, P | 5 |
| Harrap, S | 7 |
| Mancia, G | 5 |
| Poulter, N | 5 |
| Williams, B | 6 |
| Zoungas, S | 5 |
| Woodward, M | 7 |
| Chalmers, J | 10 |
| Rodgers, A | 2 |
| Lee, AK | 1 |
| Wang, D | 2 |
| Ohkuma, T | 1 |
| Warren, B | 1 |
| Sharrett, AR | 1 |
| Marre, M | 4 |
| Mcevoy, JW | 2 |
| Selvin, E | 2 |
| Raslan, IA | 1 |
| McDonald, EG | 1 |
| Lee, TC | 1 |
| Juraschek, SP | 1 |
| Lazo, M | 1 |
| Cooper, ME | 2 |
| Arima, H | 2 |
| Hirakawa, Y | 2 |
| Patel, A | 7 |
| Yamout, H | 1 |
| Bakris, GL | 1 |
| Blomster, JI | 1 |
| Li, Q | 2 |
| Chow, CK | 1 |
| Neal, B | 4 |
| Hillis, GS | 1 |
| Billot, L | 1 |
| Monaghan, H | 2 |
| Joshi, R | 3 |
| Colagiuri, S | 1 |
| Glasziou, P | 2 |
| Grobbee, D | 2 |
| Heller, S | 2 |
| Lisheng, L | 2 |
| Matthews, DR | 1 |
| Mogensen, CE | 1 |
| Perkovic, V | 4 |
| MacMahon, S | 2 |
| Kolagasi, O | 1 |
| Sari, F | 1 |
| Akar, M | 1 |
| Sari, R | 1 |
| Walker, J | 1 |
| White, R | 1 |
| Vale, A | 1 |
| Elliott, S | 1 |
| Wass, J | 1 |
| Reynolds, J | 1 |
| de Galan, BE | 1 |
| Ninomiya, T | 1 |
| Cass, A | 1 |
| Pillai, A | 1 |
| Travert, F | 1 |
| Onuchin, SG | 1 |
| Elsukova, OS | 1 |
| Solov'ev, OV | 1 |
| Onuchina, EL | 1 |
| Chaturvedi, V | 1 |
| Currie, R | 1 |
| Yaris, F | 1 |
| Yaris, E | 1 |
| Kadioglu, M | 1 |
| Ulku, C | 1 |
| Kesim, M | 1 |
| Kalyoncu, NI | 1 |
| Hartsleben, ChH | 1 |
| Battegay, E | 1 |
| Kengne, AP | 1 |
| Nagy, V | 1 |
| Davis, TM | 1 |
| Parsons, RW | 1 |
| Broadhurst, RJ | 1 |
| Hobbs, MS | 1 |
| Jamrozik, K | 1 |
| Spallarossa, P | 1 |
| Schiavo, M | 1 |
| Rossettin, P | 1 |
| Cordone, S | 1 |
| Olivotti, L | 1 |
| Cordera, R | 1 |
| Brunelli, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Action in Diabetes and Vascular Disease Preterax and Diamicron MR Controlled Evaluation Post Trial Observational Study[NCT00949286] | 8,494 participants (Actual) | Observational | 2010-01-31 | Completed | |||
| ADVANCE - Action in Diabetes and Vascular Disease: Preterax and Diamicron - MR Controlled Evaluation[NCT00145925] | Phase 3 | 11,140 participants (Actual) | Interventional | 2001-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for gliclazide and Hypertension
| Article | Year |
|---|---|
Diabetes and vascular disease: a new international trial.
Topics: Antihypertensive Agents; Developing Countries; Diabetes Complications; Diabetes Mellitus; Diabetic A | 2003 |
New insights from ADVANCE.
Topics: Antihypertensive Agents; Blood Glucose; Blood Pressure; Diabetes Complications; Diabetes Mellitus, T | 2007 |
10 trials available for gliclazide and Hypertension
| Article | Year |
|---|---|
The Risks of Cardiovascular Disease and Mortality Following Weight Change in Adults with Diabetes: Results from ADVANCE.
Topics: Adult; Aged; Body-Weight Trajectory; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug Combin | 2020 |
Response of 1,5-anhydroglucitol level to intensive glucose- and blood-pressure lowering interventions, and its associations with clinical outcomes in the ADVANCE trial.
Topics: Aged; Antihypertensive Agents; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Type 2; Drug Therapy, | 2019 |
Effects of combination of perindopril, indapamide, and calcium channel blockers in patients with type 2 diabetes mellitus: results from the Action In Diabetes and Vascular Disease: Preterax and Diamicron Controlled Evaluation (ADVANCE) trial.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, T | 2014 |
The relationship between alcohol consumption and vascular complications and mortality in individuals with type 2 diabetes.
Topics: Aged; Alcohol Drinking; Antihypertensive Agents; Coronary Disease; Diabetes Mellitus, Type 2; Diabet | 2014 |
Follow-up of blood-pressure lowering and glucose control in type 2 diabetes.
Topics: Antihypertensive Agents; Blood Glucose; Diabetes Mellitus, Type 2; Drug Combinations; Female; Follow | 2014 |
Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trial.
Topics: Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; | 2009 |
ADVANCE: breaking new ground in type 2 diabetes.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diabetes Mellitus, Type 2; Diuretics | 2006 |
[Advanced credit: patient enrolling and therapy initiation in the ADVANCE trial].
Topics: Adult; Aged; Antihypertensive Agents; Blood Glucose; Blood Pressure; Diabetes Complications; Diabete | 2007 |
Sulfonylurea treatment of type 2 diabetic patients does not reduce the vasodilator response to ischemia.
Topics: Aged; Aged, 80 and over; Blood Pressure; Brachial Artery; Diabetes Mellitus, Type 2; Diet, Diabetic; | 2001 |
Study rationale and design of ADVANCE: action in diabetes and vascular disease--preterax and diamicron MR controlled evaluation.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Clinical Protocols; Diabetes Mellitus, Type 2; Diabe | 2001 |
9 other studies available for gliclazide and Hypertension
| Article | Year |
|---|---|
Cumulative Systolic Blood Pressure Load and Cardiovascular Risk in Patients With Diabetes.
Topics: Blood Pressure; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Gliclazide; Heart Disease Risk F | 2022 |
Missed Opportunities for Deprescription: A Teachable Moment.
Topics: Aged, 80 and over; Deprescriptions; Diabetes Complications; Diabetes Mellitus; Drug Therapy, Combina | 2017 |
Evidence-based triple antihypertensive therapy yields lower mortality in older patients with diabetes mellitus.
Topics: Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dihydropyridines; Drug Combinations; Female; Gl | 2014 |
Normal pregnancy and healthy child after continued exposure to gliclazide and ramipril during pregnancy.
Topics: Adult; Diabetes Mellitus, Type 2; Female; Gliclazide; Humans; Hypertension; Infant, Newborn; Live Bi | 2009 |
Unexplained severe hypoglycaemia in hospital: a difficult diagnostic challenge.
Topics: Aged; Cholecystectomy; Diabetes Mellitus, Type 2; Gliclazide; Humans; Hypertension; Hypoglycemia; Ma | 2009 |
[Dynamics of structural-functional parameters of cardiovascular system during use of complex therapy of women with type 2 diabetes mellitus].
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Chi-Square Distribution; Data Interpretation, Statis | 2010 |
Normal pregnancy outcome following inadvertent exposure to rosiglitazone, gliclazide, and atorvastatin in a diabetic and hypertensive woman.
Topics: Adult; Anxiety Disorders; Apgar Score; Atorvastatin; Chronic Disease; Diabetes Complications; Epilep | 2004 |
[54-year-old patient with type 2 diabetes mellitus and increased blood pressure values].
Topics: Antihypertensive Agents; Blood Pressure Determination; Combined Modality Therapy; Coronary Disease; | 2005 |
Arrhythmias and mortality after myocardial infarction in diabetic patients. Relationship to diabetes treatment.
Topics: Adult; Arrhythmias, Cardiac; Diabetes Complications; Diabetes Mellitus; Digitalis Glycosides; Diuret | 1998 |