temozolomide has been researched along with Hypertension in 7 studies
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cabozantinib inhibits mesenchymal-epithelial transition factor (MET) and vascular endothelial growth factor receptor 2 (VEGFR2) and has demonstrated activity in patients with recurrent glioblastoma, warranting evaluation of the addition of cabozantinib to radiotherapy (RT) and temozolomide (TMZ) for patients with newly diagnosed high-grade glioma." | 5.22 | Phase 1 dose escalation trial of the safety and pharmacokinetics of cabozantinib concurrent with temozolomide and radiotherapy or temozolomide after radiotherapy in newly diagnosed patients with high-grade gliomas. ( Chamberlain, MC; Cloughesy, T; Desjardins, A; Glantz, M; Mikkelsen, T; Reardon, DA; Schiff, D; Wen, PY, 2016) |
| "We evaluated clinical and survival data of glioblastoma patients who underwent treatment with bevacizumab after progression under temozolomide, at CHUSJ between 2010 and 2017." | 3.96 | Hypertension and proteinuria as clinical biomarkers of response to bevacizumab in glioblastoma patients. ( Caeiro, C; Carvalho, B; Costa, A; Fernandes, AC; Linhares, P; Lopes, RG; Osório, L; Tavares, N; Vaz, R, 2020) |
| "Despite surgery, radiotherapy (RT) and temozolomide (TMZ), the prognosis of glioblastoma (GBM) patients remains dismal." | 3.81 | Impact of renin-angiotensin system blockade on clinical outcome in glioblastoma. ( Alkhafaji, A; Belin, C; Carpentier, AF; Doridam, J; Januel, E; Levy-Piedbois, C; Marantidou, A; Ursu, R, 2015) |
| "Glioblastomas are rich in blood vessels (i." | 2.58 | Anti-angiogenic therapy for high-grade glioma. ( Ameratunga, M; Grant, R; Khasraw, M; Pavlakis, N; Simes, J; Wheeler, H, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Carvalho, B | 1 |
| Lopes, RG | 1 |
| Linhares, P | 1 |
| Costa, A | 1 |
| Caeiro, C | 1 |
| Fernandes, AC | 1 |
| Tavares, N | 1 |
| Osório, L | 1 |
| Vaz, R | 1 |
| Ameratunga, M | 1 |
| Pavlakis, N | 2 |
| Wheeler, H | 2 |
| Grant, R | 2 |
| Simes, J | 1 |
| Khasraw, M | 2 |
| Ameratunga, MS | 1 |
| Januel, E | 1 |
| Ursu, R | 1 |
| Alkhafaji, A | 1 |
| Marantidou, A | 1 |
| Doridam, J | 1 |
| Belin, C | 1 |
| Levy-Piedbois, C | 1 |
| Carpentier, AF | 1 |
| Schiff, D | 1 |
| Desjardins, A | 1 |
| Cloughesy, T | 1 |
| Mikkelsen, T | 1 |
| Glantz, M | 1 |
| Chamberlain, MC | 1 |
| Reardon, DA | 1 |
| Wen, PY | 1 |
| Inamasu, J | 1 |
| Kuramae, T | 1 |
| Nakatsukasa, M | 1 |
| Dixit, S | 1 |
| Salvage, D | 1 |
| Rajaraman, C | 1 |
| Hingorani, M | 1 |
| Rowland-Hill, C | 1 |
2 reviews available for temozolomide and Hypertension
| Article | Year |
|---|---|
Anti-angiogenic therapy for high-grade glioma.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brai | 2018 |
Antiangiogenic therapy for high-grade glioma.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brai | 2014 |
1 trial available for temozolomide and Hypertension
| Article | Year |
|---|---|
Phase 1 dose escalation trial of the safety and pharmacokinetics of cabozantinib concurrent with temozolomide and radiotherapy or temozolomide after radiotherapy in newly diagnosed patients with high-grade gliomas.
Topics: Adult; Aged; Alanine Transaminase; Anilides; Antineoplastic Combined Chemotherapy Protocols; Asparta | 2016 |
4 other studies available for temozolomide and Hypertension
| Article | Year |
|---|---|
Hypertension and proteinuria as clinical biomarkers of response to bevacizumab in glioblastoma patients.
Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Immu | 2020 |
Impact of renin-angiotensin system blockade on clinical outcome in glioblastoma.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antineoplas | 2015 |
Glioblastoma masquerading as a hypertensive putaminal hemorrhage: a diagnostic pitfall.
Topics: Antihypertensive Agents; Antineoplastic Agents, Alkylating; Biopsy; Brain Neoplasms; Dacarbazine; Di | 2009 |
Hypernatremia-associated myelinolysis following the management of sepsis in a patient with glioblastoma treated with radiotherapy and temozolomide.
Topics: Antineoplastic Agents; Brain Diseases; Brain Neoplasms; Carcinoma; Carcinoma, Papillary; Dacarbazine | 2013 |