abscisic-acid and Hypertension

abscisic-acid has been researched along with Hypertension* in 2 studies

Other Studies

2 other study(ies) available for abscisic-acid and Hypertension

Article	Year
Abscisic acid priming confers salt tolerance in maize seedlings by modulating osmotic adjustment, bond energies, ROS homeostasis, and organic acid metabolism. Plant physiology and biochemistry : PPB, 2023, Volume: 202 This study aimed at investigating the influence of exogenous abscisic acid (ABA) on salt homeostasis under 100 mM NaCl stress in maize (Zea mays L. cv. Kaveri 50) through 3 and 5 days of exposure. The ratio of Na Topics: Abscisic Acid; Glutathione Reductase; Homeostasis; Hydrogen Peroxide; Hypertension; Reactive Oxygen Species; Salt Tolerance; Seedlings; Zea mays	2023
Abscisic acid ameliorates atherosclerosis by suppressing macrophage and CD4+ T cell recruitment into the aortic wall. The Journal of nutritional biochemistry, 2010, Volume: 21, Issue:12 Abscisic acid (ABA) is a natural phytohormone which improves insulin sensitivity and reduces adipose tissue inflammation when supplemented into diets of obese mice. The objective of this study was to investigate the mechanisms by which ABA prevents or ameliorates atherosclerosis. apolipoprotein E-deficient (ApoE(-/-)) mice were fed high-fat diets with or without ABA for 84 days. Systolic blood pressure was assessed on Days 0, 28, 56 and 72. Gene expression, immune cell infiltration and histological lesions were evaluated in the aortic root wall. Human aortic endothelial cells were used to examine the effect of ABA on 3',5'-cyclic adenosine monophosphate (cAMP) and nitric oxide (NO) production in vitro. We report that ABA-treated mice had significantly improved systolic blood pressure and decreased accumulation of F4/80(+)CD11b(+) macrophages and CD4(+) T cells in aortic root walls. At the molecular level, ABA significantly enhanced aortic endothelial nitric oxide synthase (eNOS) and tended to suppress aortic vascular cell adhesion molecule-1 (VCAM-1) and monocyte chemoattractant protein-1 (MCP-1) expression and plasma MCP-1 concentrations. ABA also caused a dose-dependent increase in intracellular concentrations of cAMP and NO and up-regulated eNOS mRNA expression in human aortic endothelial cells. This is the first report showing that ABA prevents or ameliorates atherosclerosis-induced hypertension, immune cell recruitment into the aortic root wall and up-regulates aortic eNOS expression in ApoE(-/-) mice. Topics: Abscisic Acid; Animals; Aorta; Atherosclerosis; Blood Pressure; CD4-Positive T-Lymphocytes; Cells, Cultured; Endothelium, Vascular; Humans; Hypertension; Inflammation; Macrophages; Mice; Mice, Knockout; Nitric Oxide Synthase Type III	2010

Article

Year

Abscisic acid priming confers salt tolerance in maize seedlings by modulating osmotic adjustment, bond energies, ROS homeostasis, and organic acid metabolism.

Plant physiology and biochemistry : PPB, 2023, Volume: 202

This study aimed at investigating the influence of exogenous abscisic acid (ABA) on salt homeostasis under 100 mM NaCl stress in maize (Zea mays L. cv. Kaveri 50) through 3 and 5 days of exposure. The ratio of Na

Topics: Abscisic Acid; Glutathione Reductase; Homeostasis; Hydrogen Peroxide; Hypertension; Reactive Oxygen Species; Salt Tolerance; Seedlings; Zea mays

2023

Abscisic acid ameliorates atherosclerosis by suppressing macrophage and CD4+ T cell recruitment into the aortic wall.

The Journal of nutritional biochemistry, 2010, Volume: 21, Issue:12

Abscisic acid (ABA) is a natural phytohormone which improves insulin sensitivity and reduces adipose tissue inflammation when supplemented into diets of obese mice. The objective of this study was to investigate the mechanisms by which ABA prevents or ameliorates atherosclerosis. apolipoprotein E-deficient (ApoE(-/-)) mice were fed high-fat diets with or without ABA for 84 days. Systolic blood pressure was assessed on Days 0, 28, 56 and 72. Gene expression, immune cell infiltration and histological lesions were evaluated in the aortic root wall. Human aortic endothelial cells were used to examine the effect of ABA on 3',5'-cyclic adenosine monophosphate (cAMP) and nitric oxide (NO) production in vitro. We report that ABA-treated mice had significantly improved systolic blood pressure and decreased accumulation of F4/80(+)CD11b(+) macrophages and CD4(+) T cells in aortic root walls. At the molecular level, ABA significantly enhanced aortic endothelial nitric oxide synthase (eNOS) and tended to suppress aortic vascular cell adhesion molecule-1 (VCAM-1) and monocyte chemoattractant protein-1 (MCP-1) expression and plasma MCP-1 concentrations. ABA also caused a dose-dependent increase in intracellular concentrations of cAMP and NO and up-regulated eNOS mRNA expression in human aortic endothelial cells. This is the first report showing that ABA prevents or ameliorates atherosclerosis-induced hypertension, immune cell recruitment into the aortic root wall and up-regulates aortic eNOS expression in ApoE(-/-) mice.

Topics: Abscisic Acid; Animals; Aorta; Atherosclerosis; Blood Pressure; CD4-Positive T-Lymphocytes; Cells, Cultured; Endothelium, Vascular; Humans; Hypertension; Inflammation; Macrophages; Mice; Mice, Knockout; Nitric Oxide Synthase Type III

2010